Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_017788291.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017796493.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017790559.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_017793734.1 16 Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176412 "APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C" XP_017795300.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017787436.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_017798339.1 7 MetaCyc: PWY-7818;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886 "Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Plasmalogen biosynthesis";"Synthesis of PC";"Synthesis of PE";"Choline biosynthesis I";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" XP_017789238.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4 "Vitamin K-epoxide cycle";"Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_017793500.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017795475.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_017794917.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism" XP_017789462.1 5 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017799283.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" XP_017792582.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017791215.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_017793845.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017797266.1 5 Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013 "Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_017794845.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017792076.1 24 Reactome: R-HSA-420092;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-163359 "Glucagon-type ligand receptors";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation" XP_017789497.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Nitrogen metabolism" XP_017798786.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017788523.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017799320.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017794468.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017791472.1 8 MetaCyc: PWY-8086;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism" XP_017789339.1 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" XP_017794276.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66 "3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_017797619.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017791947.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_017795999.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017788842.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017791100.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-180746 "SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein" XP_017788349.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017790021.1 10 Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-7328;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344 "Galactose catabolism";"D-galactose detoxification";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis" XP_017789495.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"NCAM signaling for neurite out-growth" XP_017798241.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" XP_017791306.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017791235.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_017789649.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017798377.1 12 Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-73762;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RNA Polymerase I Transcription Initiation";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Notch-HLH transcription pathway" XP_017796871.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017788260.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_017795495.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017793130.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017793433.1 11 Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"RORA activates gene expression";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_017790772.1 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017790233.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_017791589.1 8 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017795927.1 7 MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1 "L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism" XP_017794653.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017794232.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" XP_017790798.1 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_017788694.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Glyoxylate metabolism and glycine degradation";"Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport" XP_017789871.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017793015.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017798200.1 3 Reactome: R-HSA-5576893;Reactome: R-HSA-5576890;Reactome: R-HSA-1296072 "Phase 2 - plateau phase";"Phase 3 - rapid repolarisation";"Voltage gated Potassium channels" XP_017795697.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_017796816.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017799045.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017799061.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017798639.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_017795336.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017794956.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_017794393.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017792292.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_017793283.1 12 KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171 "Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_017788482.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" XP_017798602.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017788987.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_017798744.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017792048.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_017796097.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017794020.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_017795158.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017789962.1 5 MetaCyc: PWY-6168;MetaCyc: PWY-5523;Reactome: R-HSA-196843;MetaCyc: PWY-7863;KEGG: 00740+2.7.1.26 "Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"Riboflavin metabolism" XP_017790647.1 2 Reactome: R-HSA-73621;Reactome: R-HSA-500753 "Pyrimidine catabolism";"Pyrimidine biosynthesis" XP_017794545.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_017797790.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017796576.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017788150.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_017790407.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017797337.1 4 KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" XP_017796405.1 3 Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial protein import" XP_017796743.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017791890.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017788957.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017796619.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017788512.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017798834.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017793368.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_017791220.1 3 Reactome: R-HSA-8939902;Reactome: R-HSA-6785807;Reactome: R-HSA-8878166 "Regulation of RUNX2 expression and activity";"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2" XP_017790173.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression" XP_017798247.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017795590.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017791739.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017792129.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_017797157.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017799597.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017791088.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017790451.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017795609.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017797763.1 4 Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710 "Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Aggrephagy";"Late endosomal microautophagy" XP_017790653.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_017792011.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017793815.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794886.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300 "G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_017790459.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279 "Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer" XP_017796910.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017788261.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017799008.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017796818.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017789787.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_017797665.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017788065.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017789371.1 10 Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903 "WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Signal transduction by L1";"Synthesis of PC";"Receptor Mediated Mitophagy" XP_017794191.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_017797600.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" XP_017789029.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017795243.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_017794655.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017788549.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" XP_017797232.1 19 Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825 "Chylomicron remodeling";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"LDL remodeling";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"VLDL assembly";"Regulation of TLR by endogenous ligand";"LDL clearance";"Retinoid metabolism and transport";"VLDL clearance";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis" XP_017787862.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25 "Inositol phosphate metabolism";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system" XP_017793739.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017790925.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017791447.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017796440.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017794410.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017788240.1 7 Reactome: R-HSA-5685939;Reactome: R-HSA-5696395;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400 "HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER" XP_017789322.1 14 MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7587 "Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_017787723.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_017794465.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017796457.1 5 KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7 "Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism" XP_017792840.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017789329.1 8 Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism" XP_017787600.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017795149.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017797562.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14 "Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation" XP_017797523.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017796281.1 26 Reactome: R-HSA-3371497;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-9646399 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Aggrephagy" XP_017792537.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017798169.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-450408 "Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Hedgehog 'on' state";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017798410.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017792446.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Orc1 removal from chromatin";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases" XP_017799085.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017791815.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017795925.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_017792515.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_017798032.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_017791552.1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017788117.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017792293.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_017788213.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017789492.1 6 KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124 "Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II" XP_017794654.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017790878.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017797822.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-176034;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167290 "Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Interactions of Tat with host cellular proteins";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" XP_017796362.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017794477.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017790263.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis" XP_017791399.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017789595.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017788379.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_017787539.1 14 Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-5250924;Reactome: R-HSA-877300;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-2132295;Reactome: R-HSA-73863 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"B-WICH complex positively regulates rRNA expression";"Interferon gamma signaling";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"MHC class II antigen presentation";"RNA Polymerase I Transcription Termination" XP_017796179.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017792391.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017795236.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017791396.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" XP_017795539.1 4 MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_017791889.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017793362.1 4 Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511 "Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination" XP_017787644.1 9 KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00130+2.6.1.5 "Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_017793445.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017798703.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_017790269.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017796360.1 4 Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962 "G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex" XP_017790394.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017789654.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017795346.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_017798446.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017793607.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017794910.1 3 Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17 "Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" XP_017791280.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017792954.1 18 KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-6803 "Linoleic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing" XP_017788526.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017791331.1 5 KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201 "One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I" XP_017798246.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794458.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017789141.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017787660.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017793622.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_017788600.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017798202.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_017789085.1 16 Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-975138;Reactome: R-HSA-5602498;Reactome: R-HSA-1257604;Reactome: R-HSA-3134963;Reactome: R-HSA-166058;Reactome: R-HSA-5603041;Reactome: R-HSA-209543;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-6811558;Reactome: R-HSA-1810476;Reactome: R-HSA-975110;Reactome: R-HSA-5603037;Reactome: R-HSA-5602680 "ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR2/4)";"PIP3 activates AKT signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"p75NTR recruits signalling complexes";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR5)" XP_017798095.1 24 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Aggrephagy";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs" XP_017792588.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017798899.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017798193.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017790796.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017794184.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_017793486.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_017787777.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_017797264.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017798781.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017795686.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017788995.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017788991.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_017793487.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_017796864.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017791250.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017797847.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017789622.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_017795584.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017795466.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017794382.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261 "Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_017798721.1 56 Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-9010553 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs" XP_017797206.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017787877.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017799371.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017795608.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017788064.1 5 MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32 "Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Pyruvate metabolism" XP_017794283.1 3 KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis" XP_017795411.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017790463.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_017791958.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_017791716.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_017792211.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017799390.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017787829.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017796427.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017793369.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017793207.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017797192.1 10 Reactome: R-HSA-913709;MetaCyc: PWY-7979;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-4717374;MetaCyc: PWY-7921 "O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation I (yeast)" XP_017797441.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_017793094.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017793616.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017799468.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_017789541.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870 "Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins" XP_017791402.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017795810.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_017796779.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017788609.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_017790748.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;Reactome: R-HSA-3656253 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_017787811.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017792455.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_017795884.1 6 KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11 "Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism" XP_017798926.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017799046.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017793647.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_017796955.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017792893.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017788550.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017792655.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017792511.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017787422.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017790350.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription" XP_017798314.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017796780.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017796038.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_017791970.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017788067.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_017790787.1 10 MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism" XP_017794953.1 4 KEGG: 00900+2.5.1.87;Reactome: R-HSA-446199;Reactome: R-HSA-4755609;MetaCyc: PWY-6129 "Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis" XP_017791182.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" XP_017799549.1 15 Reactome: R-HSA-5358751;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-111465 "S45 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins" XP_017788678.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017788538.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017791463.1 8 KEGG: 00270+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086 "Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_017796628.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_017792201.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017788228.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017798689.1 3 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"One carbon pool by folate";"Glycine degradation" XP_017789751.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_017793303.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017798363.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis" XP_017799569.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017797069.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_017791923.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation" XP_017791262.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017790149.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation" XP_017790615.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_017787478.1 4 Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-8856825 "Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis" XP_017797700.1 15 Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017791936.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017791796.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017793722.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017792424.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_017788757.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017795161.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017790834.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017790022.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017792067.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017788874.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_017792192.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017787972.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" XP_017796917.1 6 KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290 "Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis" XP_017796216.1 16 MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-6142;Reactome: R-HSA-70263;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-7218 "1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_017794638.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_017788844.1 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_017794500.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017799130.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_017789058.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017796767.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_017788394.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017794561.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017796624.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017790318.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017797396.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790554.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_017796958.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017798809.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017789807.1 18 Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-1221632;MetaCyc: PWY-7511;Reactome: R-HSA-6804756;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648 "SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic synapsis";"Protein ubiquitination";"Regulation of TP53 Activity through Phosphorylation";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes" XP_017798716.1 18 KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis I" XP_017791843.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017790962.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017794987.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017787825.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017788229.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_017795385.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_017794952.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017795451.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017797716.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017792773.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017787464.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_017795517.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_017797769.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017795267.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_017796857.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017794330.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_017788163.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017791074.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017788104.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017794914.1 23 Reactome: R-HSA-8964315;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-418592 "G beta:gamma signalling through BTK";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1" XP_017797088.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017798376.1 4 Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017797984.1 5 Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism" XP_017794305.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017799402.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_017792303.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_017796769.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017799187.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017791278.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017789255.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_017790290.1 10 Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape" XP_017798679.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017796912.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017799023.1 6 Reactome: R-HSA-5632927;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH3";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_017797524.1 10 Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_017789540.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017788827.1 16 Reactome: R-HSA-167590;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-190873;Reactome: R-HSA-177504;Reactome: R-HSA-164939;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-196025;Reactome: R-HSA-5140745 "Nef Mediated CD4 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Gap junction degradation";"Retrograde neurotrophin signalling";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_017790479.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_017787540.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" XP_017799050.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017794924.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017790905.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_017794631.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168276 "Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"HCMV Early Events";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways" XP_017793677.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_017796361.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017794525.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_017793159.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017792388.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_017795223.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017795179.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017792647.1 3 KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_017793498.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_017796677.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017794875.1 5 MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism" XP_017788637.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017789470.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017799547.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017793732.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017792459.1 12 Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-205043 "Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus" XP_017799233.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017794350.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_017787406.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017788023.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017789372.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-445144;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-201688 "Receptor Mediated Mitophagy";"Synthesis of PC";"Signal transduction by L1";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"WNT mediated activation of DVL" XP_017793491.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017790665.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_017790423.1 18 Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167158 "TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex" XP_017793209.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017791640.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_017789678.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017788951.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_017790594.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017798462.1 10 Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3 "Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis" XP_017793831.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017799211.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_017788236.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017790782.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA" XP_017789155.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516 "Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin" XP_017792532.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017792822.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_017788843.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017788432.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017797543.1 6 KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1 "Pentose phosphate pathway";"Rubisco shunt";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms" XP_017797498.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-6782315;Reactome: R-HSA-156581;Reactome: R-HSA-6790901 "Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol";"Methylation";"rRNA modification in the nucleus and cytosol" XP_017799527.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_017798967.1 2 Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_017790719.1 7 Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71064;MetaCyc: PWY-5084 "Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_017792882.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615 "Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation" XP_017798851.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017797900.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017797518.1 10 Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-9613354 "Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Lipophagy" XP_017789944.1 10 Reactome: R-HSA-2151201;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-611105;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685 "Transcriptional activation of mitochondrial biogenesis";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species" XP_017792113.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017796135.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017788546.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017791468.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_017798616.1 13 Reactome: R-HSA-2871837;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-5607764;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-975163;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-937042 "FCERI mediated NF-kB activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"CLEC7A (Dectin-1) signaling";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex" XP_017795616.1 17 Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-110314 "HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex" XP_017797973.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997 "ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion" XP_017792711.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_017796612.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017797642.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-166208;Reactome: R-HSA-198323;Reactome: R-HSA-165159 "HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTORC1-mediated signalling";"AKT phosphorylates targets in the cytosol";"mTOR signalling" XP_017793609.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017788436.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017788409.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017789445.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017796650.1 3 MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis" XP_017788242.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" XP_017790601.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_017794930.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017794075.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_017793359.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017791317.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_017794301.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017791126.1 10 KEGG: 00670+2.1.1.45;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;Reactome: R-HSA-69205;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-3841 "One carbon pool by folate";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)" XP_017791697.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017791722.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794862.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017793928.1 11 KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-5659;KEGG: 00520+5.3.1.8;MetaCyc: PWY-6992;MetaCyc: PWY-882;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-3881;Reactome: R-HSA-4043916 "Fructose and mannose metabolism";"Mannitol degradation II";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)" XP_017796127.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_017798012.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017790875.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017794209.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017790069.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017788817.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_017797473.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" XP_017795635.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_017789385.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017799280.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017795206.1 5 MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-6692 "Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation" XP_017792263.1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_017787893.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017790289.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events" XP_017795598.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017798391.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017793916.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017792535.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017796969.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017789672.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_017791077.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017798885.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017789370.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Signal transduction by L1";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017796589.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_017788773.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827 "Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex" XP_017793250.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017789561.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017798369.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017795534.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017791885.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017789930.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017794586.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017795410.1 2 Reactome: R-HSA-196843;Reactome: R-HSA-6782861 "Vitamin B2 (riboflavin) metabolism";"Synthesis of wybutosine at G37 of tRNA(Phe)" XP_017798015.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017787650.1 13 Reactome: R-HSA-4085001;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Sialic acid metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation" XP_017794725.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017791709.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017796983.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017793793.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017795813.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017791424.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017787474.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_017790072.1 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" XP_017795687.1 42 Reactome: R-HSA-9610379;Reactome: R-HSA-912446;Reactome: R-HSA-5625886;Reactome: R-HSA-73772;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-8939236;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847;Reactome: R-HSA-1912408;Reactome: R-HSA-427359;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-110329;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222 "HCMV Late Events";"Meiotic recombination";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Escape";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"DNA methylation";"Cleavage of the damaged purine";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones";"Pre-NOTCH Transcription and Translation";"SIRT1 negatively regulates rRNA expression";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis" XP_017788675.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017792423.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_017792904.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794516.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_017792527.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_017790888.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017799267.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_017799027.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017792963.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017796376.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017792544.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017789447.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_017796170.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017789779.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017799296.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017798738.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_017793996.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017794361.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017794793.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification" XP_017794757.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017798477.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017791539.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017792765.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017797504.1 3 Reactome: R-HSA-420029;Reactome: R-HSA-2173791;Reactome: R-HSA-4608870 "Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Asymmetric localization of PCP proteins" XP_017796873.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1" XP_017793959.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_017792621.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017794565.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_017789003.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017788106.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017790713.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_017791871.1 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" XP_017789956.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017799319.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017797905.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8053 "Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II" XP_017788737.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017796206.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017797156.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017794890.1 6 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-6811440 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network" XP_017799038.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017797267.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism" XP_017797430.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017789702.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017788963.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_017795736.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017791254.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017792612.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_017788092.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017790812.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017795949.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_017789514.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017798162.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_017787843.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017790699.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017792581.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017789253.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017787592.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017797065.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_017787475.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017787985.1 24 Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-416482 "G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events" XP_017793878.1 6 Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Dual incision in TC-NER" XP_017793140.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_017788674.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017795617.1 3 Reactome: R-HSA-9639288;Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Amino acids regulate mTORC1";"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_017787976.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017793407.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017791273.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_017792573.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017799346.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017787634.1 13 Reactome: R-HSA-416572;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04150+2.7.11.1 "Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"Thermogenesis";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"mTOR signaling pathway" XP_017797571.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017788012.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-186763;Reactome: R-HSA-8875555 "MET receptor recycling";"Regulation of signaling by CBL";"Downstream signal transduction";"MET activates RAP1 and RAC1" XP_017799326.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017793701.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" XP_017793885.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_017792350.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_017790698.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_017790305.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_017798274.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017797915.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_017796933.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017796495.1 11 Reactome: R-HSA-1834949;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571 "Cytosolic sensors of pathogen-associated DNA";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)" XP_017795572.1 5 Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688 "Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Proline catabolism" XP_017793984.1 6 MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-4261 "Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol degradation I" XP_017799251.1 33 Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531 "HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus" XP_017790737.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017795865.1 17 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_017797752.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_017794303.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017790771.1 10 MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;Reactome: R-HSA-1989781;KEGG: 00072+2.3.3.10;KEGG: 00280+2.3.3.10;KEGG: 00900+2.3.3.10 "Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Butanoate metabolism";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"PPARA activates gene expression";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Terpenoid backbone biosynthesis" XP_017791903.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017796062.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017793096.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880 "Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases" XP_017789806.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017798483.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166 "Processive synthesis on the lagging strand";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate" XP_017790460.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017791304.1 9 MetaCyc: PWY-8086;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism" XP_017796663.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017798464.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017790835.1 14 MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;Reactome: R-HSA-75109;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;MetaCyc: PWY-7782 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"Sphingolipid metabolism";"Synthesis of PC";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis" XP_017798507.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017788962.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017794612.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis" XP_017792466.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017798478.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017794293.1 18 MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7227 "CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_017787656.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_017797956.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017791183.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_017795074.1 57 Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-68949 "Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"UCH proteinases";"Orc1 removal from chromatin" XP_017798356.1 6 MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-7761 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)" XP_017794918.1 5 KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism" XP_017797241.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837 "CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases" XP_017788421.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_017791994.1 4 MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181 "Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" XP_017793971.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_017795156.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017787991.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017794919.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22 "Sphingolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism" XP_017793908.1 3 MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78 "D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" XP_017789191.1 26 Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497 "Aggrephagy";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017799138.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017797911.1 5 Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" XP_017796357.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_017795441.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_017795803.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_017796167.1 1 MetaCyc: PWY-6938 "NADH repair" XP_017797236.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017789296.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017798925.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017796778.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017791777.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017793935.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017797666.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017795416.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017797824.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017798773.1 1 Reactome: R-HSA-419771 "Opsins" XP_017798766.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434 "Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017795442.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017795230.1 18 MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00710+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Arginine biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_017793390.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017796476.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017794345.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017799361.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017797955.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017789778.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017793092.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017790854.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_017791755.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_017792024.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_017796750.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017795340.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017795750.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_017796952.1 3 Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1" XP_017788955.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017792415.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017799507.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_017791559.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017798060.1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_017795625.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_017796433.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017788398.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_017796785.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017787799.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_017790163.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017795817.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017787529.1 5 Reactome: R-HSA-4793954;MetaCyc: PWY-7918;Reactome: R-HSA-532668;MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106 "Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis" XP_017793579.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_017798107.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017796611.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017791948.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017788797.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017795048.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_017792902.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017799316.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017790913.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_017796379.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_017791231.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017793200.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_017794192.1 4 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"ECM proteoglycans";"Non-integrin membrane-ECM interactions" XP_017794432.1 15 Reactome: R-HSA-8863795;Reactome: R-HSA-9634285;Reactome: R-HSA-9665247;Reactome: R-HSA-1227986;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-1236382;Reactome: R-HSA-5637810;Reactome: R-HSA-9665251;Reactome: R-HSA-9665245;Reactome: R-HSA-9665249;Reactome: R-HSA-9665250;Reactome: R-HSA-9664565;Reactome: R-HSA-9665233;Reactome: R-HSA-9665244 "Downregulation of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to AEE788";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to sapitinib" XP_017796382.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_017799160.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017796596.1 26 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_017787468.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382 "Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex" XP_017797442.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017792943.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017791025.1 2 Reactome: R-HSA-442660;Reactome: R-HSA-352230 "Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane" XP_017798439.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017793551.1 13 MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_017799310.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017796050.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017792152.1 13 Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "mTORC1-mediated signalling";"mTOR signalling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" XP_017792813.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017791309.1 4 KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism" XP_017799217.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_017793462.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017795083.1 6 MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I" XP_017789825.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_017795769.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017793005.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017788283.1 3 KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" XP_017796401.1 26 Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-983189 "RHO GTPases activate IQGAPs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins" XP_017790379.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_017797395.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_017796017.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017788357.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017795676.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_017789262.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_017789593.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_017790398.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017797495.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017794199.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017791435.1 4 Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607 "Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Ub-specific processing proteases";"Processing of DNA double-strand break ends" XP_017788631.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722 "Glycine, serine and threonine metabolism";"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)" XP_017798633.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_017798543.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017794879.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017790428.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_017794041.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017795605.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017799035.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017788563.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017789351.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017795685.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_017788586.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017792058.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "Josephin domain DUBs";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_017787798.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017793262.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017799335.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_017792232.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017788724.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017798479.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017791703.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_017794344.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017795245.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017787659.1 3 MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96 "L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis" XP_017798402.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017795712.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017788876.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017788049.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017798673.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_017792414.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017793674.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569 "HCMV Early Events";"Regulation of MECP2 expression and activity";"PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_017792534.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017790222.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017796542.1 5 Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-5221030 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"TET1,2,3 and TDG demethylate DNA" XP_017796828.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_017789261.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017791415.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017799497.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017790046.1 7 KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;Reactome: R-HSA-174403;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;MetaCyc: PWY-6840;MetaCyc: PWY-8043 "Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Homoglutathione biosynthesis";"Ophthalmate biosynthesis" XP_017794131.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017793958.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017787484.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_017798212.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_017798522.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017798400.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_017797016.1 13 Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5 "Citric acid cycle (TCA cycle)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes" XP_017795347.1 32 Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152 "Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017793298.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_017792149.1 19 Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-983231 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"Rho GTPase cycle";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"Myogenesis";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"Factors involved in megakaryocyte development and platelet production" XP_017798371.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017790651.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017793001.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-416993;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-76005 "G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+" XP_017788171.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017789851.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_017789343.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_017789293.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017798424.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" XP_017788433.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017788989.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_017797384.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_017797784.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017790468.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-165054 "HCMV Early Events";"ISG15 antiviral mechanism";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA" XP_017796604.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis" XP_017794230.1 9 MetaCyc: PWY-7411;MetaCyc: PWY-7385;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166 "Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA" XP_017789947.1 5 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin" XP_017797617.1 13 MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7198;KEGG: 00983+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_017789140.1 8 Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828 "Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis" XP_017796506.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_017798704.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_017796169.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017795270.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790224.1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827 "Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex" XP_017789434.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017796718.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017797933.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692 "Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity" XP_017794347.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163615 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation" XP_017797848.1 6 Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_017790590.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_017790023.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_017797938.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;MetaCyc: PWY-7511 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"Protein ubiquitination" XP_017791727.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_017798605.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903 "Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy" XP_017790448.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017798934.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017794267.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017787921.1 7 Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-2894862 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017792210.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017796813.1 7 Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2 "TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism" XP_017795869.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017787796.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017796945.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017798983.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017792717.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_017799588.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_017787606.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724 "MAP2K and MAPK activation";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription" XP_017789437.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" XP_017789723.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017790354.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017799250.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017793019.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017793562.1 3 MetaCyc: PWY-0;MetaCyc: PWY-6117;KEGG: 00330+2.3.1.57 "Putrescine degradation III";"Spermine and spermidine degradation I";"Arginine and proline metabolism" XP_017797429.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_017791439.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_017788358.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017797372.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017796575.1 6 MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" XP_017798174.1 10 MetaCyc: PWY-6317;MetaCyc: PWY-7328;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6397 "D-galactose degradation I (Leloir pathway)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Galactose catabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis" XP_017796600.1 6 MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183 "D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_017796113.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017796666.1 6 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_017795365.1 17 Reactome: R-HSA-975163;Reactome: R-HSA-9014325;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-9645460;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-937072;Reactome: R-HSA-937042;Reactome: R-HSA-450302;Reactome: R-HSA-5689880;Reactome: R-HSA-4086398;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956 "IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Downstream TCR signaling";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"Alpha-protein kinase 1 signaling pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IRAK2 mediated activation of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Ub-specific processing proteases";"Ca2+ pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway" XP_017797947.1 18 MetaCyc: PWY-7205;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-7224 "CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage" XP_017798116.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_017799028.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017792844.1 13 Reactome: R-HSA-8876725;Reactome: R-HSA-532668;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-3371511;Reactome: R-HSA-5689877;Reactome: R-HSA-110320;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896 "Protein methylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Aggrephagy";"ABC-family proteins mediated transport";"Neutrophil degranulation";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"HSF1 activation";"Josephin domain DUBs";"Translesion Synthesis by POLH";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases" XP_017799237.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017794306.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017796863.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_017789301.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex" XP_017787766.1 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_017787758.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017796762.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017789146.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017796798.1 11 Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-68962 "PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex" XP_017799253.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017794899.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017790231.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_017798927.1 8 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Recycling pathway of L1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_017798364.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017796249.1 4 KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerol degradation I" XP_017793972.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_017794771.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017792191.1 6 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-264876;Reactome: R-HSA-6811438 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Insulin processing";"Intra-Golgi traffic" XP_017791128.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017794425.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017793340.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017791175.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_017792107.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017798475.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017794320.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017790773.1 4 Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017790303.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017796045.1 37 Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-983170;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9639288;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-204005;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295 "Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Amino acids regulate mTORC1";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"COPII-mediated vesicle transport";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"ISG15 antiviral mechanism";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"MHC class II antigen presentation" XP_017788105.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017794557.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017796100.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_017792949.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_017792354.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017797161.1 12 Reactome: R-HSA-2691232;Reactome: R-HSA-982772;Reactome: R-HSA-1442490;Reactome: R-HSA-1251985;Reactome: R-HSA-75893;Reactome: R-HSA-2122948;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Growth hormone receptor signaling";"Collagen degradation";"Nuclear signaling by ERBB4";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017790535.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" XP_017789684.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_017795246.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017793139.1 3 Reactome: R-HSA-420029;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017794751.1 3 Reactome: R-HSA-727802;Reactome: R-HSA-5619078;Reactome: R-HSA-6787639 "Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis" XP_017793827.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017789853.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017794134.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_017794348.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231 "PKA activation";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production" XP_017792339.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017796010.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017797108.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_017799351.1 16 Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530 "G alpha (q) signalling events";"Interleukin-7 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Rho GTPase cycle";"PIP3 activates AKT signaling";"RET signaling";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_017790132.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017787581.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017791136.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017798929.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017796378.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017788162.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017798278.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017795600.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017795557.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-2129379 "ECM proteoglycans";"Syndecan interactions";"Integrin cell surface interactions";"Molecules associated with elastic fibres" XP_017794096.1 4 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin" XP_017791673.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017791981.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" XP_017790497.1 2 Reactome: R-HSA-69231;Reactome: R-HSA-8934593 "Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity" XP_017792031.1 24 Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-2871837;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1 "Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"FCERI mediated NF-kB activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"mTOR signaling pathway";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"RSK activation";"Thermogenesis";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Relaxin signaling pathway" XP_017798056.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017790024.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017791147.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017789494.1 5 MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6 "Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism" XP_017797210.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_017793930.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-72163 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_017799386.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017793906.1 26 Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-174414;Reactome: R-HSA-1362277;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-4615885;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-69205;Reactome: R-HSA-6782210;Reactome: R-HSA-8866654;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-6804114;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606 "Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"SUMOylation of DNA replication proteins";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"G1/S-Specific Transcription";"Gap-filling DNA repair synthesis and ligation in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_017790690.1 18 Reactome: R-HSA-1482922;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Ether lipid metabolism" XP_017795349.1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944 "Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2" XP_017790020.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_017794799.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017793859.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination" XP_017799213.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017795759.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_017788682.1 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex" XP_017799227.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017789012.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_017794895.1 14 MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51 "CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Glycerophospholipid metabolism" XP_017795483.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_017788803.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_017794475.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism" XP_017797522.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-9619483;Reactome: R-HSA-200425;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Activation of AMPK downstream of NMDARs";"Carnitine metabolism";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017789647.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017790165.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017792321.1 8 MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-66 "GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)" XP_017797242.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017796089.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017794457.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017796733.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_017793455.1 9 MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-7411;MetaCyc: PWY-7385;MetaCyc: PWY-5981 "Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III" XP_017795588.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017798559.1 56 Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664 "Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Degradation of DVL";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation" XP_017799462.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017797775.1 52 Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-5250924;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-749476;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167243 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"B-WICH complex positively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcriptional regulation by small RNAs";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery" XP_017793322.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017798403.1 3 KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942 "Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism" XP_017799112.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_017792155.1 4 Reactome: R-HSA-2408557;Reactome: R-HSA-379716;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_017787460.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017797961.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_017796635.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017793681.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_017797464.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_017795225.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017798026.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017794508.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_017787802.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_017791758.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_017787495.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_017797517.1 7 MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_017794748.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_017791114.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170670 "G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway" XP_017798238.1 4 MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism" XP_017788778.1 13 KEGG: 00230+3.6.1.66;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine catabolism";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Pyrimidine metabolism" XP_017796560.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017787879.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism" XP_017788978.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017792054.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017796846.1 15 MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_017797282.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017797637.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" XP_017795595.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017795351.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017796957.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017796299.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017798898.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017792186.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_017796214.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_017790597.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017792852.1 13 Reactome: R-HSA-5689896;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-8866654;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-9646399;Reactome: R-HSA-532668;Reactome: R-HSA-8876725 "Ovarian tumor domain proteases";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Translesion Synthesis by POLH";"HSF1 activation";"E3 ubiquitin ligases ubiquitinate target proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Aggrephagy";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein methylation" XP_017790067.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017797481.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_017793812.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017790777.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017796601.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912 "XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane" XP_017798159.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_017795264.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_017795491.1 1 Reactome: R-HSA-419771 "Opsins" XP_017795785.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017788811.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_017794384.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017796317.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_017798152.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_017790813.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_017797189.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017787413.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017789137.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017789049.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017794980.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017788045.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017790002.1 29 Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-77075 "Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE" XP_017788294.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017793400.1 12 MetaCyc: PWY-6672;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5132;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1 "Cis-genanyl-coa degradation";"Glyoxylate and dicarboxylate metabolism";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Methane metabolism";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Propanoate metabolism" XP_017795487.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017789174.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017791132.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017796693.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017798045.1 12 MetaCyc: PWY-3801;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9 "Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism" XP_017795823.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017798630.1 10 Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017789235.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017796155.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017793567.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017798099.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_017796336.1 11 Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation" XP_017789516.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_017792183.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017798655.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017797722.1 17 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017792514.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_017794830.1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-195253 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex" XP_017797199.1 16 Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290 "RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation" XP_017792801.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017789065.1 7 Reactome: R-HSA-446193;KEGG: 00510+2.7.8.15;MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6470;Reactome: R-HSA-4549356 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2" XP_017798129.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017790216.1 7 MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183 "Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_017796944.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017788499.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017788372.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_017795566.1 6 Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_017796529.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017793613.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017795085.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus" XP_017798432.1 3 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis" XP_017792068.1 3 Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760 "RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation" XP_017787496.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017791744.1 10 MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001 "4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_017795414.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017799101.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017797924.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_017789598.1 7 Reactome: R-HSA-6798695;KEGG: 00510+2.4.1.142;KEGG: 00790+3.4.19.9;KEGG: 00513+2.4.1.142;Reactome: R-HSA-6791226;MetaCyc: PWY-2161B;Reactome: R-HSA-6790901 "Neutrophil degranulation";"N-Glycan biosynthesis";"Folate biosynthesis";"Various types of N-glycan biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Glutamate removal from folates";"rRNA modification in the nucleus and cytosol" XP_017794640.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_017799179.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017797623.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017798309.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017789653.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017790140.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-165054 "HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA" XP_017791989.1 14 Reactome: R-HSA-112043;Reactome: R-HSA-418217;MetaCyc: PWY-7039;Reactome: R-HSA-399997;KEGG: 00562+3.1.4.11;Reactome: R-HSA-4086398;MetaCyc: PWY-8052;Reactome: R-HSA-500657;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-434316 "PLC beta mediated events";"G beta:gamma signalling through PLC beta";"Phosphatidate metabolism, as a signaling molecule";"Acetylcholine regulates insulin secretion";"Inositol phosphate metabolism";"Ca2+ pathway";"2-arachidonoylglycerol biosynthesis";"Presynaptic function of Kainate receptors";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_017792928.1 6 Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1" XP_017787377.1 16 Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176412 "APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C" XP_017788063.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_017793513.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017793645.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_017790843.1 14 Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053;Reactome: R-HSA-4419969 "Synthesis of PE";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Synthesis of PC";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina" XP_017791622.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_017790541.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_017791775.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017790506.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017797935.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017792580.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017798984.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017791288.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017796537.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017797247.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5987;MetaCyc: PWY-5996 "Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)" XP_017788443.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017794262.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_017792863.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017798144.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017789237.1 3 KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle" XP_017799391.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017787725.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_017793507.1 20 Reactome: R-HSA-9639288;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"Human papillomavirus infection";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"mTOR signalling";"mTORC1-mediated signalling";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_017788520.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)" XP_017792891.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017792091.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_017793345.1 57 Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481 "Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints" XP_017798328.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis" XP_017793296.1 4 MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450 "Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"tRNA modification in the mitochondrion" XP_017789926.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017789254.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017798097.1 24 Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Aggrephagy" XP_017799327.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017793941.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017798176.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_017793271.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_017794888.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017794851.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport" XP_017787916.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_017797869.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017788468.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017788828.1 16 Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-190873;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-164939;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-416993 "MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"Gap junction degradation";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"Nef mediated downregulation of CD28 cell surface expression";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Trafficking of GluR2-containing AMPA receptors" XP_017789850.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" XP_017790246.1 18 Reactome: R-HSA-1482839;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051 "Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis I" XP_017788857.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_017799352.1 16 Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-1433557;Reactome: R-HSA-9009391 "G alpha (q) signalling events";"Interleukin-7 signaling";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Rho GTPase cycle";"Regulation of signaling by CBL";"RET signaling";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by SCF-KIT";"Extra-nuclear estrogen signaling" XP_017788297.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017798774.1 1 Reactome: R-HSA-419771 "Opsins" XP_017792406.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017797459.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_017790117.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_017791433.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017798291.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-9609523;Reactome: R-HSA-6807878 "Cargo concentration in the ER";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"COPI-mediated anterograde transport" XP_017788994.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_017792288.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_017792865.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017793201.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_017797761.1 9 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" XP_017789021.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_017789080.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_017790892.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1474228;Reactome: R-HSA-1442490 "Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix";"Collagen degradation" XP_017796533.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_017798637.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases" XP_017797468.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017791707.1 5 MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism" XP_017793987.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017793738.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017795797.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017793940.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_017791547.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017789876.1 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" XP_017789564.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017797182.1 12 Reactome: R-HSA-205043;Reactome: R-HSA-9017802;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-977225 "NRIF signals cell death from the nucleus";"Noncanonical activation of NOTCH3";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation" XP_017789490.1 5 KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817 "Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis" XP_017789320.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017797171.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017791721.1 11 Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017797263.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017790299.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_017799540.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017796603.1 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis" XP_017792849.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_017793948.1 4 KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" XP_017789257.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_017797946.1 20 Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169 "Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis" XP_017794202.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_017790367.1 13 MetaCyc: PWY-6969;Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7384 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_017799328.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017795326.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017799410.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017799276.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017787458.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017796358.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_017797497.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_017795073.1 57 Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-450408 "Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017790375.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017793267.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase" XP_017792203.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017792367.1 7 KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336;MetaCyc: PWY-8004;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Chitin derivatives degradation" XP_017794279.1 6 KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane" XP_017790127.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_017790757.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination" XP_017796842.1 15 MetaCyc: PWY-6142;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-8004;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Rubisco shunt";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycolysis";"Glycolysis / Gluconeogenesis";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)" XP_017798857.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017793434.1 11 Reactome: R-HSA-9018519;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_017795354.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_017799254.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017794540.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017794210.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017799362.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017793284.1 12 Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861 "Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_017790738.1 12 MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5871;MetaCyc: PWY-7233;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-7230;Reactome: R-HSA-2142789 "Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis" XP_017789982.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017792719.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017790764.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017789382.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex" XP_017790666.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017795101.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017792495.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_017798098.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-983189 "RHO GTPases activate IQGAPs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Kinesins" XP_017796090.1 52 Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152 "PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Transcriptional regulation by small RNAs";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017790593.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017790964.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017788435.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017795130.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-450408 "Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_017790154.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017798173.1 10 KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-7328;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317 "Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)" XP_017795325.1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847 "UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones" XP_017797436.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017787383.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017793134.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_017793435.1 11 Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519 "Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression" XP_017798388.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017793530.1 13 Reactome: R-HSA-71403;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5538;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5 "Citric acid cycle (TCA cycle)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes" XP_017790469.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3371453 "HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response" XP_017792727.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017798276.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017789064.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_017795086.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187 "tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing" XP_017798165.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017799207.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017795202.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism" XP_017795778.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_017788894.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017799002.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017798672.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_017787443.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017799169.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017790010.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_017795895.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017799259.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017790478.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017795774.1 3 Reactome: R-HSA-948021;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_017799272.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017793366.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_017793432.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108 "PPARA activates gene expression";"RORA activates gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_017792478.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017789788.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017794317.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017799240.1 3 KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17 "Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism" XP_017794985.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017789862.1 5 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation" XP_017794239.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_017798447.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017790837.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_017791963.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_017797804.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017787971.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell" XP_017793740.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017796461.1 6 MetaCyc: PWY-5651;Reactome: R-HSA-71240;MetaCyc: PWY-7765;MetaCyc: PWY-6309;KEGG: 00380+1.14.13.9;MetaCyc: PWY-7717 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I" XP_017791950.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017798449.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017798058.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017789491.1 5 MetaCyc: PWY-6124;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6 "Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism" XP_017789889.1 7 Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-201681;Reactome: R-HSA-4086400 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"Degradation of DVL";"TCF dependent signaling in response to WNT";"PCP/CE pathway" XP_017796067.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017798729.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-6605;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Neutrophil degranulation";"Adenine salvage";"Purine salvage";"Adenine and adenosine salvage II";"Purine metabolism";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_017795120.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression" XP_017796441.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_017789932.1 4 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017793431.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017795135.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017796036.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_017789342.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_017796705.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017797648.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105 "Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation" XP_017791490.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017792233.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017796713.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017795718.1 8 Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Photosynthesis";"Insulin receptor recycling";"ATP biosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes" XP_017794464.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017799302.1 42 Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-110331;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-912446;Reactome: R-HSA-5625886;Reactome: R-HSA-73772;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-171306;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-73728;Reactome: R-HSA-110329;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815 "PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged purine";"DNA methylation";"HCMV Late Events";"Meiotic recombination";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RNA Polymerase I Promoter Escape";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Packaging Of Telomere Ends";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"RNA Polymerase I Promoter Opening";"Cleavage of the damaged pyrimidine";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones" XP_017789305.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends" XP_017789643.1 4 Reactome: R-HSA-9033241;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9 "Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"beta-Alanine metabolism" XP_017790397.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017790351.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017795891.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017798393.1 6 Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5673001;Reactome: R-HSA-9028731 "FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"RAF/MAP kinase cascade";"Activated NTRK2 signals through FRS2 and FRS3" XP_017799066.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-180534 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4" XP_017796007.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017794271.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_017788061.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017798825.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017799314.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017790364.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_017797155.1 33 MetaCyc: PWY-5082;MetaCyc: PWY-7111;MetaCyc: PWY-7013;MetaCyc: PWY-6871;MetaCyc: PWY-1801;MetaCyc: PWY-6342;MetaCyc: PWY-6313;MetaCyc: PWY-5078;KEGG: 00626+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-7396;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-5751;MetaCyc: PWY-6802;KEGG: 00625+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5057;KEGG: 00071+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00592+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-7118;MetaCyc: PWY-7798;MetaCyc: PWY-5076;KEGG: 00350+1.1.1.1;KEGG: 00680+1.1.1.284;KEGG: 00260+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-6333;MetaCyc: PWY-5486;KEGG: 00010+1.1.1.1 "L-methionine degradation III";"Pyruvate fermentation to isobutanol (engineered)";"(S)-propane-1,2-diol degradation";"3-methylbutanol biosynthesis (engineered)";"Formaldehyde oxidation II (glutathione-dependent)";"Noradrenaline and adrenaline degradation";"Serotonin degradation";"L-isoleucine degradation II";"Naphthalene degradation";"Pyruvate fermentation to ethanol III";"Butanol and isobutanol biosynthesis (engineered)";"Retinol metabolism";"Pyruvate fermentation to ethanol I";"Phenylethanol biosynthesis";"Salidroside biosynthesis";"Chloroalkane and chloroalkene degradation";"Drug metabolism - cytochrome P450";"L-valine degradation II";"Fatty acid degradation";"Metabolism of xenobiotics by cytochrome P450";"L-phenylalanine degradation III";"alpha-Linolenic acid metabolism";"L-tryptophan degradation V (side chain pathway)";"Chitin degradation to ethanol";"Protein S-nitrosylation and denitrosylation";"L-leucine degradation III";"Tyrosine metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism";"Ethanol oxidation";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to ethanol II";"Glycolysis / Gluconeogenesis" XP_017789590.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017795981.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017791010.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_017795494.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017796153.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-4086400 "Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"PCP/CE pathway" XP_017793564.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017799067.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017791483.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017792283.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_017792330.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017797329.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168 "Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017788961.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017793997.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017793332.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017791047.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_017791267.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017799271.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5632684 "Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"UCH proteinases";"Orc1 removal from chromatin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Hedgehog 'on' state" XP_017797667.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_017788800.1 2 KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23 "Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_017797084.1 4 Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"DNA methylation" XP_017798399.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_017787616.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_017797303.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_017788729.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69183 "Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Processive synthesis on the lagging strand" XP_017790049.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017798366.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_017794907.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_017793000.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597 "Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events" XP_017789268.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017791818.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017794840.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312 "Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1" XP_017791334.1 3 KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_017799051.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-202040 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G-protein activation" XP_017794101.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-8937144;Reactome: R-HSA-211981;Reactome: R-HSA-211976 "PPARA activates gene expression";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling";"Xenobiotics";"Endogenous sterols" XP_017787978.1 3 Reactome: R-HSA-2024101;Reactome: R-HSA-2206296;Reactome: R-HSA-2024096 "CS/DS degradation";"MPS II - Hunter syndrome";"HS-GAG degradation" XP_017792198.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_017787596.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_017793224.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017798488.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017790070.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017792703.1 6 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-3878781;MetaCyc: PWY-7900;Reactome: R-HSA-3322077 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen synthesis" XP_017794229.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion" XP_017798675.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017790856.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs" XP_017789273.1 2 MetaCyc: PWY-7802;MetaCyc: PWY-7799 "N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)" XP_017798667.1 17 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6783310;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-1221632 "mTOR signaling pathway";"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"Thermogenesis";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Meiotic synapsis" XP_017787851.1 8 KEGG: 00950+1.14.16.2;MetaCyc: PWY-6133;Reactome: R-HSA-209905;MetaCyc: PWY-3581;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-5394;KEGG: 00790+1.14.16.2 "Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Tyrosine metabolism";"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"Folate biosynthesis" XP_017791419.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108 "Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_017798896.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017789024.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017791614.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288 "Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1" XP_017789484.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017797634.1 10 Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756 "SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation" XP_017789673.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720 "Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_017788157.1 15 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167287 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery" XP_017791600.1 29 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-69541;Reactome: R-HSA-5693565;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5693548;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-6803204;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-6804760;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Relaxin signaling pathway";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Stabilization of p53";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Degradation";"mTOR signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Sensing of DNA Double Strand Breaks";"Human immunodeficiency virus 1 infection";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Methylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017798268.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_017789360.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450321;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580 "FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Oxidative Stress Induced Senescence" XP_017789410.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017792243.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017792258.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_017793577.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_017791090.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017794843.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_017788022.1 52 Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-167161;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-167287 "RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"HIV Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery" XP_017794582.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_017794743.1 7 KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017788541.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017799238.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017796770.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017791949.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017795338.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017799225.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017796124.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_017793829.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017792467.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017797632.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017798003.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017796228.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017792944.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017794894.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-110314;Reactome: R-HSA-6783310 "Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway" XP_017796771.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017792033.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017788369.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017795843.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_017793788.1 5 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_017789983.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017788684.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017797704.1 19 KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;Reactome: R-HSA-163765;KEGG: 00720+2.3.3.8;Reactome: R-HSA-6798695;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00020+2.3.3.8;Reactome: R-HSA-75105;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5172;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913 "Propanoate metabolism";"Citric acid cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Acetyl-coa biosynthesis III (from citrate)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)" XP_017791643.1 5 KEGG: 00533+2.4.1.68;KEGG: 00513+2.4.1.68;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578 "Glycosaminoglycan biosynthesis - keratan sulfate";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway" XP_017798209.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017788765.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017799031.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017788739.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017796044.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017798047.1 12 KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801 "Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Galactose metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)" XP_017797540.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_017797268.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017798887.1 4 Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-3359462 "HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1" XP_017798767.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017789153.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_017787590.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017788411.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017791971.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017798133.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017795350.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017789922.1 8 Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017798006.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51 "Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerophospholipid metabolism" XP_017789927.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" XP_017791107.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)" XP_017791617.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017795049.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_017788040.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017797104.1 1 Reactome: R-HSA-196757 "Metabolism of folate and pterines" XP_017790528.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017796891.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_017797859.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017787767.1 4 Reactome: R-HSA-209931;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4 "Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis" XP_017794364.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017792666.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017798817.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017790026.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_017788689.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_017787681.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017793715.1 5 Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_017798092.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017790104.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_017797967.1 12 KEGG: 00920+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4 "Sulfur metabolism";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Purine metabolism";"Purine metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Selenocompound metabolism" XP_017799409.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017787440.1 5 KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95;KEGG: 00270+1.1.1.95;MetaCyc: PWY-8010 "Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)" XP_017793338.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017787439.1 5 Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00260+1.1.1.95;KEGG: 00270+1.1.1.95;KEGG: 00680+1.1.1.95 "Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Methane metabolism" XP_017793771.1 4 MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_017790446.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin" XP_017790277.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017789440.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_017791504.1 42 MetaCyc: PWY-6583;MetaCyc: PWY-7094;MetaCyc: PWY-5136;MetaCyc: PWY-6883;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-6863;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5177;MetaCyc: PWY-7216;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6944;MetaCyc: PWY-1361;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-7007;MetaCyc: PWY-5138;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00592+4.2.1.17 "Pyruvate fermentation to butanol I";"Fatty acid salvage";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to butanol II (engineered)";"Propanoate metabolism";"2-methylpropene degradation";"Tryptophan metabolism";"Geraniol degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to hexanol (engineered)";"Lysine degradation";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"beta-Alanine metabolism";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Benzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Limonene and pinene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Glutaryl-coa degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Androstenedione degradation";"Benzoyl-coa degradation I (aerobic)";"Caprolactam degradation";"Aminobenzoate degradation";"Spodoptera littoralis pheromone biosynthesis";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Toluene degradation";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"alpha-Linolenic acid metabolism" XP_017792135.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017798615.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017788982.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_017798993.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_017788931.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001 "Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism" XP_017799100.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017790470.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-180746 "SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein" XP_017791292.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis" XP_017793801.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017788673.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017788494.1 2 Reactome: R-HSA-216083;Reactome: R-HSA-913709 "Integrin cell surface interactions";"O-linked glycosylation of mucins" XP_017788619.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_017789387.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017792110.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017792255.1 3 Reactome: R-HSA-202433;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Generation of second messenger molecules";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017794696.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_017790649.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_017787818.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_017792539.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017795771.1 3 Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "Rap1 signalling";"cGMP effects";"Ca2+ pathway" XP_017794585.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017792497.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017789905.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017795482.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_017794559.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017791794.1 7 MetaCyc: PWY-31;Reactome: R-HSA-70635;MetaCyc: PWY-46;MetaCyc: PWY-4984;MetaCyc: PWY-6922;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1 "Canavanine degradation";"Urea cycle";"Putrescine biosynthesis III";"Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine biosynthesis";"Arginine and proline metabolism" XP_017793208.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017791437.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017799372.1 16 Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154 "Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin" XP_017794509.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER" XP_017799317.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017790937.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017790324.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017789865.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_017797917.1 22 KEGG: 00520+5.3.1.9;KEGG: 00500+5.3.1.9;Reactome: R-HSA-6798695;MetaCyc: PWY-5384;MetaCyc: PWY-622;KEGG: 00010+5.3.1.9;MetaCyc: PWY-6992;MetaCyc: PWY-5514;MetaCyc: PWY-8013;Reactome: R-HSA-70171;MetaCyc: PWY-621;MetaCyc: PWY-7347;Reactome: R-HSA-5628897;MetaCyc: PWY-5054;MetaCyc: PWY-7385;MetaCyc: PWY-6981;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-5659;Reactome: R-HSA-70263;MetaCyc: PWY-3801;MetaCyc: PWY-6142 "Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neutrophil degranulation";"Sucrose degradation IV (sucrose phosphorylase)";"Starch biosynthesis";"Glycolysis / Gluconeogenesis";"1,5-anhydrofructose degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Glycolysis";"Sucrose degradation III (sucrose invertase)";"Sucrose biosynthesis III";"TP53 Regulates Metabolic Genes";"D-sorbitol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Chitin biosynthesis";"Pentose phosphate pathway";"Sucrose biosynthesis II";"GDP-mannose biosynthesis";"Gluconeogenesis";"Sucrose degradation II (sucrose synthase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017791459.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017789259.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017788355.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_017790803.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017794982.1 17 KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383 "Methane metabolism";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_017794887.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017797959.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_017795471.1 5 MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_017799308.1 42 Reactome: R-HSA-427413;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-912446;Reactome: R-HSA-5625886;Reactome: R-HSA-9610379;Reactome: R-HSA-171306;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-5250924;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-110329;Reactome: R-HSA-73728;Reactome: R-HSA-3214815;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-5693565;Reactome: R-HSA-977225;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5578749;Reactome: R-HSA-5693607 "NoRC negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"Meiotic recombination";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HCMV Late Events";"Packaging Of Telomere Ends";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"DNA methylation";"Cleavage of the damaged purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Opening";"HDACs deacetylate histones";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Transcriptional regulation by small RNAs";"Processing of DNA double-strand break ends" XP_017790836.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017798742.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017788401.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017789078.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017796915.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017790908.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_017799369.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949664 "Mitochondrial protein import";"Processing of SMDT1" XP_017788264.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017795811.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017796258.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017797381.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017793468.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017789760.1 27 Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-180910 "Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs" XP_017788336.1 17 Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167200;KEGG: 04660+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167152;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167287;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167242 "Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"T cell receptor signaling pathway";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_017796502.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017790477.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017794584.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017790045.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017797828.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_017792194.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_017790501.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017798520.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017787708.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017798022.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017791929.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_017796338.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017791456.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017791434.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017795677.1 17 Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-69183;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-110314 "Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex" XP_017794370.1 6 MetaCyc: PWY-7238;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-6731 "Sucrose biosynthesis II";"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Starch degradation III" XP_017791853.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017793350.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017796745.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_017788647.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017792278.1 17 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5358565;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-174417 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis" XP_017791708.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017792570.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017796492.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_017796128.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_017788769.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017792421.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_017795079.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_017796459.1 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7 "Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis" XP_017798953.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "Syndecan interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_017798319.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017790794.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_017793973.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_017798494.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_017799205.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_017788677.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017795075.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017794975.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-3232142;Reactome: R-HSA-1234176 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"SUMOylation of ubiquitinylation proteins";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_017788051.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017792531.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" XP_017787426.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017793818.1 2 Reactome: R-HSA-416482;Reactome: R-HSA-456926 "G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017792983.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_017793591.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017794780.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_017793173.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_017794066.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017795993.1 9 KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.25;KEGG: 00604+3.2.1.23;Reactome: R-HSA-8853383;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Sphingolipid metabolism";"Galactose metabolism";"Neutrophil degranulation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Lysosomal oligosaccharide catabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation" XP_017798353.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017793559.1 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017795000.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_017797909.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017797367.1 6 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Triglyceride catabolism";"Circadian Clock";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling" XP_017792123.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_017794563.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017798882.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_017798465.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017797327.1 4 Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_017790230.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_017797304.1 4 Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-381033 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones" XP_017793450.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_017799321.1 19 Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-5663213;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-5625970;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-194840;Reactome: R-HSA-3928662 "RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate WASPs and WAVEs";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"RHO GTPases activate KTN1";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"Rho GTPase cycle";"EPHB-mediated forward signaling" XP_017794797.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_017788403.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017791009.1 33 Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-180746 "Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein" XP_017792097.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_017790435.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017788992.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017797116.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" XP_017787555.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017794562.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_017791284.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017791466.1 3 MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315 "Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol" XP_017789303.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_017794656.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017789247.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017797352.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017799041.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790596.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017789615.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017794599.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017792973.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017791567.1 4 Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-6798695 "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation" XP_017790733.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_017794207.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_017799172.1 6 KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism" XP_017798131.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017792567.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017788639.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017793569.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017796442.1 7 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70268 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Pyruvate metabolism" XP_017791004.1 5 KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;MetaCyc: PWY-7782;Reactome: R-HSA-75896;Reactome: R-HSA-9033500 "Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins" XP_017791782.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017798248.1 3 Reactome: R-HSA-2514859;Reactome: R-HSA-8876725;KEGG: 00310+2.1.1.60 "Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation";"Lysine degradation" XP_017792892.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017793261.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017795958.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_017788666.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017793188.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_017789609.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_017789902.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017796477.1 4 Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_017796918.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Meiotic synapsis";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_017789251.1 7 Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017797154.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_017789504.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_017796058.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017787819.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_017788630.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_017796339.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017791257.1 14 Reactome: R-HSA-3371497;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5620924;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-141444 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Macroautophagy";"HCMV Early Events";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intraflagellar transport";"Mitotic Prometaphase";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017791812.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017792318.1 8 Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids" XP_017799049.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017798932.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017798971.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017788585.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017794842.1 7 KEGG: 00860+6.1.1.17;Reactome: R-HSA-6782315;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716 "Porphyrin and chlorophyll metabolism";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017795801.1 8 Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017796889.1 17 Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176412 "APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C" XP_017787594.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_017793370.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017791551.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-4551638 "HCMV Early Events";"Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins" XP_017790166.1 29 Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-73863 "Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Termination" XP_017793496.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017788434.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017788816.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_017796426.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017795277.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_017795821.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_017799266.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017795449.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017788557.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_017788093.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017794132.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017792590.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_017789874.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_017798663.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_017793713.1 4 MetaCyc: PWY-6823;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_017787930.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_017796963.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017796985.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017799553.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017788498.1 6 MetaCyc: PWY-622;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900 "Starch biosynthesis";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_017798106.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017795412.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017794349.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615 "PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation" XP_017789083.1 12 KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-6978;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-5870 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_017787684.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017795501.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017793461.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017789594.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017793191.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_017794274.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66 "3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_017788830.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_017797477.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017797324.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_017794741.1 6 KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes" XP_017789004.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-418889 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand" XP_017797122.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017796267.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017788560.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017790412.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017794963.1 11 Reactome: R-HSA-9614657;Reactome: R-HSA-163680;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972 "FOXO-mediated transcription of cell death genes";"AMPK inhibits chREBP transcriptional activation activity";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017796651.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_017791968.1 8 Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354 "Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy" XP_017794669.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017795882.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_017797309.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017794501.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017796532.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_017798720.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017792019.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_017796849.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_017797659.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_017791554.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_017792604.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_017794740.1 6 KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism" XP_017792144.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_017788985.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017793744.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017797626.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation" XP_017796817.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_017792457.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017798867.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017791072.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017791768.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_017797245.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-3371571;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"HSF1-dependent transactivation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_017788301.1 7 KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202 "Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Metabolism of polyamines" XP_017792015.1 4 Reactome: R-HSA-4717374;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-162699 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of dolichyl-phosphate mannose" XP_017792146.1 56 Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-983168 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017787685.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017791315.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_017792441.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017787757.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017788071.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017798547.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017794929.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017791227.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017792207.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017794189.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017787642.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5656169 "Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Termination of translesion DNA synthesis" XP_017798091.1 8 Reactome: R-HSA-163754;MetaCyc: PWY-1861;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;Reactome: R-HSA-6791055;MetaCyc: PWY-5723;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_017794609.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017791676.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017793444.1 17 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-174178;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9648025;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2500257;Reactome: R-HSA-9022692;KEGG: 04714+2.7.11.1;Reactome: R-HSA-141444;KEGG: 04926+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human cytomegalovirus infection";"EML4 and NUDC in mitotic spindle formation";"mTOR signaling pathway";"Resolution of Sister Chromatid Cohesion";"Regulation of MECP2 expression and activity";"Thermogenesis";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Relaxin signaling pathway" XP_017797246.1 3 MetaCyc: PWY-5996;MetaCyc: PWY-5987;Reactome: R-HSA-75105 "Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis" XP_017789679.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017798801.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017789808.1 9 MetaCyc: PWY-7003;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12 "Glycerol degradation to butanol";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms" XP_017788722.1 7 KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-3841;Reactome: R-HSA-69205 "One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate transformations II (plants)";"G1/S-Specific Transcription" XP_017787561.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017796914.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017798203.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017789386.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017789395.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_017788314.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_017793076.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017789987.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017795183.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017798157.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017797725.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017799030.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017798960.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017791627.1 8 Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-4661;MetaCyc: PWY-6664;MetaCyc: PWY-6372;MetaCyc: PWY-2301 "Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis" XP_017791259.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_017799252.1 9 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation" XP_017794304.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017788144.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_017789006.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017789946.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017791946.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017789260.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017797056.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017789088.1 7 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.14 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes" XP_017795492.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017789805.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017793349.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017793351.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_017791714.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017791207.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017793229.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_017790909.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_017795772.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017798870.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation";"S-adenosyl-L-methionine cycle II" XP_017789861.1 5 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109;Reactome: R-HSA-1482883 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG" XP_017790945.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_017788476.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017798918.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017792651.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017793821.1 3 Reactome: R-HSA-429958;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "mRNA decay by 3' to 5' exoribonuclease";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017796975.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017790877.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017792022.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_017788528.1 7 KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11 "Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis / Gluconeogenesis" XP_017788766.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017788910.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017798782.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017794792.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017795521.1 9 Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol" XP_017796579.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017799325.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_017793315.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_017794351.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664 "Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation" XP_017793802.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017795612.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017790700.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017797868.1 18 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017789687.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017797098.1 8 MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.9 "Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism" XP_017791874.1 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_017793844.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017793692.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590 "Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation" XP_017797188.1 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_017795833.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017794861.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017798069.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation" XP_017789143.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1" XP_017791204.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017789280.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017799353.1 16 Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-912526;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604;Reactome: R-HSA-912631;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-512988;Reactome: R-HSA-1433557 "Interleukin-7 signaling";"G alpha (q) signalling events";"Interleukin receptor SHC signaling";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RET signaling";"PIP3 activates AKT signaling";"Regulation of signaling by CBL";"Rho GTPase cycle";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by SCF-KIT" XP_017787918.1 29 Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781823 "mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex" XP_017792966.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017796541.1 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism" XP_017790174.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017792265.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017795806.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_017797772.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017795218.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_017794921.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism" XP_017796075.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017790283.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_017798282.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs" XP_017790366.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017798830.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017790758.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017789510.1 27 Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-4570464 "Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"ISG15 antiviral mechanism";"HCMV Early Events";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins" XP_017797072.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017793393.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_017797344.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017796031.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606 "Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017793921.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017791852.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017797364.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_017789087.1 7 KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14 "Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism" XP_017795457.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017787928.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017796776.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017792609.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017797851.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_017792215.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017796263.1 3 Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex" XP_017797228.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017796636.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_017794744.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis" XP_017793936.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_017788344.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017788484.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017796499.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176 "Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_017792526.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_017797159.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017796424.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_017791491.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_017788832.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_017793312.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_017791587.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Activation of RAC1" XP_017787532.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017789936.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_017798599.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017793610.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017793023.1 3 Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3;Reactome: R-HSA-5657562 "Fructose catabolism";"Fructose and mannose metabolism";"Essential fructosuria" XP_017789977.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-9020702 "Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling" XP_017790298.1 33 Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-2500257 "Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"HCMV Late Events";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion" XP_017792465.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017793488.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017790750.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_017795819.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_017797939.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "Protein ubiquitination";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_017794259.1 3 Reactome: R-HSA-1358803;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017790044.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_017794718.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_017797858.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_017791842.1 10 Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5684264 "Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation" XP_017788170.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017788688.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_017788480.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017798184.1 16 Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-180585;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery" XP_017795315.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017796123.1 4 MetaCyc: PWY-7919;KEGG: 00513+3.2.1.113;Reactome: R-HSA-901032;KEGG: 00510+3.2.1.113 "Protein N-glycosylation processing phase (plants and animals)";"Various types of N-glycan biosynthesis";"ER Quality Control Compartment (ERQC)";"N-Glycan biosynthesis" XP_017796432.1 4 Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation" XP_017792992.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_017790938.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017788492.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_017793528.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017790546.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035 "RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_017796714.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017788738.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017797457.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017798009.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017795748.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_017798804.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017790326.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_017794564.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_017793014.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_017795110.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017793689.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017799592.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017798784.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017794878.1 5 MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism" XP_017792089.1 11 Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170670 "G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway" XP_017798607.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017792985.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017792824.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_017792744.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_017793234.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020 "Regulation of HSF1-mediated heat shock response";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import" XP_017794995.1 40 Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcriptional regulation by small RNAs";"mRNA Capping";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_017787955.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017797470.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017790429.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_017798380.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_017788244.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017791251.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017798601.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017795420.1 6 KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987 "Biotin metabolism";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_017789369.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"Synthesis of PC";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017791190.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017795671.1 9 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis" XP_017788804.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017793688.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017793679.1 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" XP_017787813.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017793792.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017794753.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_017795753.1 31 MetaCyc: PWY-8047;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5367;MetaCyc: PWY-5989;Reactome: R-HSA-2426168;MetaCyc: PWY-4381;MetaCyc: PWY-5973;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-5142;MetaCyc: PWY-7723;MetaCyc: PWY-5971;MetaCyc: PWY-6113;MetaCyc: PWY-5994;Reactome: R-HSA-199220;Reactome: R-HSA-75105;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-7746;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-6519 "Bryostatin biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Petroselinate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Bacterial bioluminescence";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Pederin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"8-amino-7-oxononanoate biosynthesis I" XP_017787776.1 3 Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807 "Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_017791611.1 8 MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5743 "Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle" XP_017794814.1 15 Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398 "Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway" XP_017788096.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017789079.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017787562.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017795820.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_017798113.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion" XP_017789984.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017791357.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_017787840.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex" XP_017793939.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_017799590.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-72163 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_017796119.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_017788268.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017793155.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017795328.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017795477.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_017787910.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017797534.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017790007.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_017790587.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_017788481.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription" XP_017797322.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_017793281.1 7 MetaCyc: PWY-7625;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11 "Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Glycerophospholipid metabolism" XP_017796149.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" XP_017787487.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_017793699.1 8 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;MetaCyc: PWY-7922 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_017798293.1 16 Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-2467813 "APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids" XP_017793947.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_017791685.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_017793255.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017797360.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_017796224.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017787471.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_017787878.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017796638.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_017799099.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_017798828.1 17 KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115 "Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_017789608.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of PTEN localization" XP_017793489.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017799529.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_017788515.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_017798611.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_017791320.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_017790704.1 10 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-437239 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"RSK activation";"Recycling pathway of L1" XP_017797881.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017792051.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_017799564.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017797695.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_017794047.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" XP_017798398.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_017791218.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination" XP_017788100.1 13 Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04150+2.7.11.1 "Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling downstream of RAS mutants";"mTOR signaling pathway" XP_017792111.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017787979.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_017793374.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_017790630.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_017799242.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017790139.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017798141.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017798194.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017789705.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017798275.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017793081.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017797100.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017788640.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017797415.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017793138.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017787564.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017798643.1 6 Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-6722 "Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis" XP_017788173.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017796323.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017792261.1 13 KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-156590;Reactome: R-HSA-196836 "Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione conjugation";"Vitamin C (ascorbate) metabolism" XP_017789573.1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_017797837.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017798699.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_017797987.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017794155.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017790229.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017799400.1 7 KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017794745.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_017789730.1 9 Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTORC1-mediated signalling";"mTOR signalling" XP_017793501.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_017791964.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017794604.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017793643.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017793124.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_017788751.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_017788088.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-6794361 "RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Neurexins and neuroligins" XP_017796934.1 14 Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167246 "Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript" XP_017798996.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017799568.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_017797766.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017791266.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017790237.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017797874.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_017788406.1 30 Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-69231;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-1170546;Reactome: R-HSA-2644607;Reactome: R-HSA-983168 "Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Cyclin D associated events in G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"Neddylation";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Prolactin receptor signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017799574.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017791386.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017790454.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017788496.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017795887.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230 "RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA" XP_017791841.1 10 Reactome: R-HSA-5676590;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-2565942 "NIK-->noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition" XP_017793741.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017796901.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017797425.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017799196.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_017798375.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_017788602.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_017793205.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361 "Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins" XP_017791761.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-201722 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex" XP_017793204.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_017798980.1 6 MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5664 "Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_017792363.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_017788980.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins" XP_017793464.1 20 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis" XP_017797153.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_017790112.1 11 Reactome: R-HSA-72163;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-210744;Reactome: R-HSA-8941856 "mRNA Splicing - Major Pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling" XP_017789708.1 4 MetaCyc: PWY-7383;MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism" XP_017795456.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017799086.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_017791239.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017791564.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_017796233.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017795001.1 10 KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895;MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-7996;MetaCyc: PWY-5839;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-5892;MetaCyc: PWY-5891 "Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-7 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis" XP_017796884.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017796929.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" XP_017794099.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_017791642.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017795976.1 7 MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;MetaCyc: PWY-6471;MetaCyc: PWY-5265;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_017799043.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017796282.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017791269.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017789695.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017797091.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532 "Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" XP_017790667.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017792200.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017792663.1 9 Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events" XP_017791409.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_017792507.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017787907.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017795462.1 5 KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;MetaCyc: PWY-7766;MetaCyc: PWY-5531;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis" XP_017796245.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794727.1 7 KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-7234;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-6124 "Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II" XP_017794739.1 6 Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import" XP_017788430.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017791405.1 3 Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271 "GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_017798518.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017794798.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017790341.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017795890.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_017787909.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017795749.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_017798707.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017796687.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017798051.1 12 Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9 "Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Galactose metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Starch and sucrose metabolism" XP_017789675.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024 "Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events" XP_017798875.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017789887.1 10 Reactome: R-HSA-983231;Reactome: R-HSA-427413;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-8936459;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692 "Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity" XP_017790916.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017798404.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017798408.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017793909.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_017798295.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017797810.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition" XP_017796909.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017796264.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017794581.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_017791260.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-164378 "G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Hedgehog 'off' state";"PKA activation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling" XP_017794081.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017796613.1 1 Reactome: R-HSA-419771 "Opsins" XP_017797223.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017792823.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017788826.1 57 Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8939236 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_017792280.1 12 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery" XP_017794145.1 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_017794742.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017791155.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017798856.1 5 Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;Reactome: R-HSA-376172 "p38MAPK events";"mTOR signaling pathway";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions" XP_017793352.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_017795862.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" XP_017793036.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_017792642.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_017792608.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017793125.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_017795249.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_017794217.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017791478.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_017797862.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017788174.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017797724.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017793737.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017792825.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017793570.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017795665.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_017789102.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017797664.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017791268.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017787744.1 6 KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-5497 "Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine nucleobases degradation II (anaerobic)" XP_017798878.1 4 KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II" XP_017794542.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017798930.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport" XP_017788851.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017787852.1 8 MetaCyc: PWY-5049;KEGG: 00350+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-3581;KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394 "Rosmarinic acid biosynthesis II";"Tyrosine metabolism";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis";"(S)-reticuline biosynthesis I";"Folate biosynthesis";"Betalamic acid biosynthesis" XP_017796061.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017788249.1 52 Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-5250924;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"B-WICH complex positively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Transcriptional regulation by small RNAs";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_017788664.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-174430 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"DNA replication initiation";"Telomere C-strand synthesis initiation" XP_017798187.1 16 Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-983168 "Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017799150.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" XP_017787890.1 24 Reactome: R-HSA-9010642;Reactome: R-HSA-381676;Reactome: R-HSA-5621575;Reactome: R-HSA-163358;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-422356;Reactome: R-HSA-8853659;Reactome: R-HSA-5687128;Reactome: R-HSA-111931;Reactome: R-HSA-5610783;Reactome: R-HSA-164378;Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-442720;Reactome: R-HSA-5610785;Reactome: R-HSA-9634600;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780;Reactome: R-HSA-432040;Reactome: R-HSA-8963896;Reactome: R-HSA-4420097;Reactome: R-HSA-163615 "ROBO receptors bind AKAP5";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of key metabolic factors";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"Regulation of insulin secretion";"RET signaling";"MAPK6/MAPK4 signaling";"PKA-mediated phosphorylation of CREB";"Degradation of GLI2 by the proteasome";"PKA activation in glucagon signalling";"Triglyceride catabolism";"Rap1 signalling";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"GLI3 is processed to GLI3R by the proteasome";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"mTOR signaling pathway";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"HDL assembly";"VEGFA-VEGFR2 Pathway";"PKA activation" XP_017791672.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_017794765.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-445355 "Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction" XP_017791167.1 19 Reactome: R-HSA-2408557;Reactome: R-HSA-3214858;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"RMTs methylate histone arginines";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_017790273.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017797972.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316 "G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_017798600.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_017792519.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017787579.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_017799347.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_017788025.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017792784.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017797010.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017792065.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017790853.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628 "ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_017793742.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017790697.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_017789496.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6798695 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Neutrophil degranulation" XP_017795943.1 3 Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320 "Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH" XP_017789016.1 10 Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563 "RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription" XP_017795578.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_017798492.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017793872.1 32 Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-8851708;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-72203 "Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"mRNA Capping";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA" XP_017789873.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017794538.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017790135.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_017796747.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_017797313.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017798114.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_017798894.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841 "Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines" XP_017791339.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_017798180.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_017793039.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_017792030.1 24 KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;Reactome: R-HSA-392451;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5625740;Reactome: R-HSA-5674400;Reactome: R-HSA-5218921 "Thermogenesis";"RSK activation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"CLEC7A (Dectin-1) signaling";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"mTOR signaling pathway";"Regulation of TP53 Degradation";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"G beta:gamma signalling through PI3Kgamma";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"RHO GTPases activate PKNs";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated cell proliferation" XP_017788956.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017795826.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017795722.1 13 Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_017788390.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017791861.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_017790715.1 9 MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017796930.1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation" XP_017788216.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017797762.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017799180.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017794933.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_017794687.1 25 Reactome: R-HSA-416476;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-381771;Reactome: R-HSA-428930;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-456926 "G alpha (q) signalling events";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_017799158.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017791891.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017789289.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_017788654.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_017789483.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017797434.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017794072.1 5 Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409 "Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation" XP_017790600.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_017790948.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017799273.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017793069.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017792970.1 5 Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017790857.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105 "Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation" XP_017799113.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017797957.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017797101.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017792584.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017787990.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017788426.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017792057.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_017795597.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017789937.1 8 MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "Cardiolipin biosynthesis II";"Synthesis of PG";"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017794915.1 5 MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism" XP_017791286.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017795077.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017787698.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_017795148.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017796597.1 7 Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system" XP_017795403.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry" XP_017793363.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017794161.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_017791189.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017799102.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017788252.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_017792316.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017788848.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017792145.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-8001 "Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_017794255.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017797258.1 4 Reactome: R-HSA-71737;MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Pyrophosphate hydrolysis";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_017791715.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017797643.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_017798546.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_017794630.1 4 KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603 "Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine" XP_017792586.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017791839.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017788474.1 14 Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781 "Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)" XP_017798751.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-9639288 "Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1" XP_017796865.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017789523.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017793021.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017791570.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017791626.1 5 KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation" XP_017791937.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_017798807.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_017798818.1 8 KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway" XP_017793603.1 7 KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7198;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;MetaCyc: PWY-7184 "Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_017791020.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_017799389.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017798330.1 18 Reactome: R-HSA-71064;KEGG: 00260+1.8.1.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00640+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-71403;KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00010+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00380+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00310+1.8.1.4 "Lysine catabolism";"Glycine, serine and threonine metabolism";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Propanoate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Signaling by Retinoic Acid";"Tryptophan metabolism";"Glycine degradation";"Lysine degradation" XP_017789389.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017795879.1 5 KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33 "Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" XP_017792757.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017791358.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_017796309.1 5 Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785 "Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome" XP_017793611.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017793422.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017792789.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017796364.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017794365.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017787785.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017796397.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_017788319.1 5 Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948 "RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants" XP_017789686.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017788473.1 5 KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556 "Arginine biosynthesis";"Arginine and proline metabolism";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes" XP_017788581.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017787998.1 12 KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972 "PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"Macroautophagy";"mTOR signaling pathway";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017799133.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017792229.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017793608.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_017789733.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_017796960.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017790816.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" XP_017793481.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_017788676.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017794976.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_017789748.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017795599.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017799132.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_017797644.1 34 Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-8939236;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-69656;Reactome: R-HSA-112382 "Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of RNA Pol II elongation complex" XP_017788855.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" XP_017793391.1 5 Reactome: R-HSA-3232118;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" XP_017790793.1 34 Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-9639288;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-3232142;Reactome: R-HSA-180746 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amino acids regulate mTORC1";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein" XP_017796013.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_017793719.1 7 Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-5620922 "Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium" XP_017788536.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017789988.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752 "S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RAF activation";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated" XP_017795332.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017794524.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_017795758.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017788169.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017791711.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_017798890.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" XP_017789605.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519 "Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression" XP_017798010.1 4 Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656 "Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry" XP_017796268.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464 "SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins" XP_017799300.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017787465.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017797771.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017793923.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_017789985.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7177;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I" XP_017788863.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_017793547.1 5 Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017799368.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017793540.1 11 Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783 "Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type" XP_017792141.1 5 Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046 "Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA" XP_017793589.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017798810.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_017795335.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017788668.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017787756.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_017798808.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_017792585.1 7 Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472 "HCMV Early Events";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017788850.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017794925.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017792845.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping" XP_017793406.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017799349.1 16 Reactome: R-HSA-512988;Reactome: R-HSA-1433557;Reactome: R-HSA-9009391;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-912526;Reactome: R-HSA-1266695;Reactome: R-HSA-416476 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signaling by SCF-KIT";"Extra-nuclear estrogen signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"Rho GTPase cycle";"Regulation of signaling by CBL";"RET signaling";"PIP3 activates AKT signaling";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin receptor SHC signaling";"Interleukin-7 signaling";"G alpha (q) signalling events" XP_017790285.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_017795314.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion" XP_017790511.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_017792289.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_017795606.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017796916.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017795953.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017796322.1 7 Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838 "Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO" XP_017797867.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017788444.1 26 Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606;Reactome: R-HSA-201722;Reactome: R-HSA-1989781;Reactome: R-HSA-3899300;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-9617629;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408 "HATs acetylate histones";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"PPARA activates gene expression";"SUMOylation of transcription cofactors";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Regulation of FOXO transcriptional activity by acetylation";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation" XP_017799047.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790968.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017792946.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017797809.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_017790825.1 5 MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_017798837.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_017793615.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017788389.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017795259.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017790307.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017792661.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017798569.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_017788899.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_017792861.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017793253.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_017788348.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_017795272.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_017796870.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017792864.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017789053.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_017791282.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017795136.1 52 Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-5250924;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-72163;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-427413;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-1834949;Reactome: R-HSA-6781823;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-72203;Reactome: R-HSA-5601884 "Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Major Pathway";"Transcriptional regulation by small RNAs";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"NoRC negatively regulates rRNA expression";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Cytosolic sensors of pathogen-associated DNA";"Formation of TC-NER Pre-Incision Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis" XP_017795454.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017789909.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50 "HS-GAG degradation";"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation" XP_017798977.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_017789657.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017789156.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017793381.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017788795.1 4 Reactome: R-HSA-73817;MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2 "Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism" XP_017790971.1 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359471;KEGG: 00860+2.5.1.17 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Porphyrin and chlorophyll metabolism" XP_017794292.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" XP_017793494.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017792320.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017799184.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling" XP_017788986.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening" XP_017798288.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017797197.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" XP_017793902.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_017793305.1 3 KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_017792572.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017796437.1 6 Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16 "Circadian Clock";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation" XP_017792579.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017797295.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017787637.1 5 Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017793133.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017791851.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017797788.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017787410.1 33 Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464 "Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins" XP_017788289.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017791263.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017796768.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017791706.1 5 KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)" XP_017799318.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017790806.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_017795808.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_017789287.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017790425.1 18 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_017793938.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_017789400.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017788933.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017793981.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9 "Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_017790257.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_017798939.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017791884.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" XP_017790753.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017789690.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_017788988.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_017792153.1 13 Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-380972;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757 "mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"Energy dependent regulation of mTOR by LKB1-AMPK";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Regulation of TP53 Degradation" XP_017793295.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_017793897.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017798642.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017796485.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017799313.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017799472.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017793543.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017793035.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_017788820.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017798768.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017798544.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017793203.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958 "Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)" XP_017791618.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_017789281.1 25 Reactome: R-HSA-8936459;Reactome: R-HSA-8940973;Reactome: R-HSA-8951911;Reactome: R-HSA-8939236;Reactome: R-HSA-8935964;Reactome: R-HSA-8939245;Reactome: R-HSA-8939256;Reactome: R-HSA-8941332;Reactome: R-HSA-8939242;Reactome: R-HSA-8949275;Reactome: R-HSA-8939243;Reactome: R-HSA-8877330;Reactome: R-HSA-9018519;Reactome: R-HSA-8941284;Reactome: R-HSA-8941326;Reactome: R-HSA-8934593;Reactome: R-HSA-8931987;Reactome: R-HSA-8951936;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902;Reactome: R-HSA-9616222;Reactome: R-HSA-8941858;Reactome: R-HSA-8939247;Reactome: R-HSA-8939246;Reactome: R-HSA-8941333 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX2 regulates osteoblast differentiation";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Estrogen-dependent gene expression";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates bone development";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX3 regulates p14-ARF";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity";"Transcriptional regulation of granulopoiesis";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in differentiation of myeloid cells" XP_017795513.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017788597.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017793168.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_017797362.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017796247.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017789103.1 14 MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;Reactome: R-HSA-70895;MetaCyc: PWY-5104;MetaCyc: PWY-5101;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5076;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108 "L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis II";"Cysteine and methionine metabolism";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"L-leucine degradation III";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V" XP_017798572.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017797243.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-442982 "Phase 0 - rapid depolarisation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017793070.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017791536.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017789061.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-437239;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295 "Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"Recycling pathway of L1";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation" XP_017795779.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_017787896.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017795854.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-2559585;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593 "Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Oncogene Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity" XP_017789270.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017792285.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_017787795.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017790921.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017799490.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_017789824.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017791066.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017791883.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017792187.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_017791393.1 5 Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability" XP_017792147.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_017787618.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" XP_017791638.1 15 Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-9603505 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"NTRK3 as a dependence receptor" XP_017796246.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017799248.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_017787518.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017798000.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017788601.1 13 Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"LDL clearance";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis" XP_017799392.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017797173.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017799600.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017798680.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017799565.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017793424.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017796936.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_017792026.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_017799557.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017792281.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017789350.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_017797480.1 6 KEGG: 00520+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346 "Amino sugar and nucleotide sugar metabolism";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_017793240.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_017791819.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017789133.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_017796375.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols" XP_017796417.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017792327.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017799486.1 3 Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511 "Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination" XP_017799229.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017789839.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017793676.1 6 Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781 "HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HCMV Early Events";"Regulation of MECP2 expression and activity";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression" XP_017787437.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_017792029.1 24 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-5607764;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;Reactome: R-HSA-392451 "mTOR signaling pathway";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"Relaxin signaling pathway";"Thermogenesis";"RSK activation";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"Human papillomavirus infection";"Human cytomegalovirus infection";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma" XP_017793127.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_017797587.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_017793192.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017788779.1 3 Reactome: R-HSA-447043;Reactome: R-HSA-3928664;Reactome: R-HSA-6798695 "Neurofascin interactions";"Ephrin signaling";"Neutrophil degranulation" XP_017796547.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017797764.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_017790563.1 19 Reactome: R-HSA-8964026;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497 "Chylomicron clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"LDL remodeling";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Platelet sensitization by LDL";"VLDL assembly";"Retinoid metabolism and transport";"LDL clearance";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors" XP_017791732.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017794461.1 4 MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189 "Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)" XP_017795228.1 18 MetaCyc: PWY-7115;KEGG: 00270+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_017789396.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_017789365.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_017791151.1 2 Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Formation of apoptosome" XP_017794391.1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" XP_017792351.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017789860.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_017793702.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017790047.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017796856.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_017794672.1 4 Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis" XP_017797985.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017792125.1 5 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-917937 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Iron uptake and transport" XP_017798239.1 4 Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_017798234.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017788787.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017788215.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017797774.1 6 Reactome: R-HSA-1483166;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;MetaCyc: PWY-7817;Reactome: R-HSA-1483148;MetaCyc: PWY-5269 "Synthesis of PA";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"Cardiolipin biosynthesis II" XP_017794788.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017792957.1 1 Reactome: R-HSA-156581 "Methylation" XP_017787435.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017797519.1 10 Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-200425;Reactome: R-HSA-9619483 "AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs" XP_017795855.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017791954.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_017797976.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-434316 "Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_017796300.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017795327.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017795564.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017798431.1 3 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism" XP_017796205.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017799511.1 8 MetaCyc: PWY-7980;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "ATP biosynthesis";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_017790507.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017797975.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017795886.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017793568.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017797478.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017788866.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_017793994.1 57 Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442 "ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs" XP_017799552.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017788727.1 19 Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-381426 "VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Chylomicron assembly";"Retinoid metabolism and transport";"LDL clearance";"Post-translational protein phosphorylation";"LDL remodeling";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Platelet sensitization by LDL";"VLDL assembly";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_017797884.1 3 KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_017795571.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017788556.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790383.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017794668.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9604323 "Orc1 removal from chromatin";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling" XP_017787414.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_017798473.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017797572.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_017790264.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017791134.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;MetaCyc: PWY-7511 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination" XP_017791116.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017791484.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_017788188.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017793337.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_017798661.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017793003.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_017795373.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017790417.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_017796654.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017788777.1 57 Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome" XP_017796800.1 13 MetaCyc: PWY-5030;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-6613 "L-histidine degradation III";"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate transformations II (plants)";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate" XP_017796752.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017794505.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017793865.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017795604.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017797991.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017795455.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017794916.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Galactose metabolism";"Sphingolipid metabolism" XP_017798871.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_017798164.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017792634.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017790680.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017791792.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_017789139.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-196025 "WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_017791176.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_017795185.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017795203.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017792413.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017796967.1 8 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Neutrophil degranulation";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_017791052.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_017794702.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017792574.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017789894.1 19 KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00710+1.1.1.37;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-70263;MetaCyc: PWY-6728;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622 "Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)" XP_017797740.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017793999.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017792374.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017793007.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_017791639.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation" XP_017794366.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_017787754.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017791588.1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017790598.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017789890.1 8 Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6611;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-6798695 "Surfactant metabolism";"Purine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Neutrophil degranulation" XP_017791216.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017796073.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017793703.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_017795520.1 9 Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway" XP_017792442.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017789272.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_017796616.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017797941.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-8948751 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN";"Protein ubiquitination";"Regulation of PTEN stability and activity" XP_017793421.1 33 Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-168333;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-9648025;Reactome: R-HSA-168271;Reactome: R-HSA-9610379 "tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events" XP_017798975.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_017794700.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs" XP_017797044.1 18 MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5690;Reactome: R-HSA-70263;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37 "Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Methane metabolism" XP_017798678.1 14 Reactome: R-HSA-975634;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783 "Retinoid metabolism and transport";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation" XP_017787614.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" XP_017799171.1 6 Reactome: R-HSA-70370;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317 "Galactose catabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_017797041.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017797366.1 6 Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"Circadian Clock";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017797255.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_017790522.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3769402;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472 "Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Deactivation of the beta-catenin transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017798776.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" XP_017796486.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017799559.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_017792968.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_017792839.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017788569.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_017799307.1 42 Reactome: R-HSA-110329;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-606279;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-427359;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-110330;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-5625886;Reactome: R-HSA-912446;Reactome: R-HSA-73772;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-110331;Reactome: R-HSA-5334118 "Cleavage of the damaged pyrimidine";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Deposition of new CENPA-containing nucleosomes at the centromere";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"SIRT1 negatively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Amyloid fiber formation";"Recognition and association of DNA glycosylase with site containing an affected purine";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"HCMV Late Events";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic recombination";"RNA Polymerase I Promoter Escape";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged purine";"DNA methylation" XP_017788155.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)" XP_017787752.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-112043 "Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events" XP_017795114.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582 "Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)" XP_017792077.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_017793903.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_017796157.1 12 KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-7901;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6936;KEGG: 00450+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-6842;MetaCyc: PWY-2821 "Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Tryptophan metabolism";"Seleno-amino acid biosynthesis (plants)";"Selenocompound metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine" XP_017792462.1 14 Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Neutrophil degranulation";"Nuclear signaling by ERBB4" XP_017796168.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017787528.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_017792218.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017799385.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017797863.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017799521.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017792464.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017793665.1 22 Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340 "APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"RAF activation";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex" XP_017787566.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204 "Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_017789640.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_017797165.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017794372.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex" XP_017794943.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA" XP_017794823.1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_017791704.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017796040.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_017793700.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017797738.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017789729.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017788493.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_017792841.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017798050.1 12 MetaCyc: PWY-7238;MetaCyc: PWY-3801;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343 "Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I" XP_017798701.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_017791252.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017794016.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017788288.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017796839.1 5 MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-7761 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)" XP_017795121.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73762 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_017797877.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_017787559.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017798149.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017787686.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017789674.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615 "PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation" XP_017793022.1 3 Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3 "Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism" XP_017789121.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_017789995.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_017798294.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174178 "Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017796164.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017798049.1 12 KEGG: 00052+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9 "Galactose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Stachyose degradation";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_017798688.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017791291.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017791892.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017791156.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_017795318.1 14 Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781 "Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)" XP_017793091.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_017788788.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017790396.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_017792381.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation" XP_017791222.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017792561.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017791397.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017793154.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_017793828.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_017790214.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017791520.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017787504.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_017789838.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017797866.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_017790073.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-936440;Reactome: R-HSA-1169408 "Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling";"ISG15 antiviral mechanism" XP_017790819.1 12 MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053 "Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II" XP_017788679.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794138.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017795607.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017794791.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017788547.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017799044.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790746.1 9 Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135 "Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER" XP_017795807.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_017788540.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_017788041.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" XP_017790186.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_017798357.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017790852.1 14 MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;MetaCyc: PWY-7782 "Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Triglyceride biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PC";"Plasmalogen biosynthesis" XP_017794265.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017787617.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_017799108.1 8 Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Activation of RAC1";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_017795858.1 11 Reactome: R-HSA-8943724;Reactome: R-HSA-450341;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8862803;Reactome: R-HSA-6796648;Reactome: R-HSA-5687128;Reactome: R-HSA-2871796 "Regulation of PTEN gene transcription";"Activation of the AP-1 family of transcription factors";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"TP53 Regulates Transcription of DNA Repair Genes";"MAPK6/MAPK4 signaling";"FCERI mediated MAPK activation" XP_017794287.1 12 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"Rho GTPase cycle";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017797974.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997 "Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion" XP_017789169.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017790692.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017798210.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_017798783.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017797502.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017793316.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_017798266.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017792223.1 6 MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-446199;KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" XP_017797423.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017796615.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017799404.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_017790557.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017793061.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017788330.1 17 Reactome: R-HSA-9616222;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-69656;Reactome: R-HSA-8953750;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-111448;Reactome: R-HSA-69205;Reactome: R-HSA-2559585;Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-113501;Reactome: R-HSA-139915 "Transcriptional regulation of granulopoiesis";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Activation of NOXA and translocation to mitochondria";"G1/S-Specific Transcription";"Oncogene Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of PUMA and translocation to mitochondria" XP_017789059.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017790391.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017797745.1 3 MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695 "Glutamate removal from folates";"Folate biosynthesis";"Neutrophil degranulation" XP_017792313.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017795097.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_017790833.1 9 Reactome: R-HSA-9656255;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-110357;Reactome: R-HSA-5649702;Reactome: R-HSA-9656256;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Defective OGG1 Substrate Binding";"Cleavage of the damaged purine";"Defective OGG1 Localization";"Displacement of DNA glycosylase by APEX1";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_017795395.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017797067.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017797906.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017793882.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017787479.1 4 Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440 "Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" XP_017787845.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017797414.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_017794999.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_017792732.1 11 KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9 "Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism" XP_017795569.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017792730.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_017796692.1 6 MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_017795238.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017799388.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017791799.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-8053 "Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II" XP_017791497.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017788438.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017793871.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_017791001.1 2 MetaCyc: PWY-6502;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins" XP_017788680.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017793297.1 11 Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519 "Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Generic Transcription Pathway";"PPARA activates gene expression";"RORA activates gene expression";"Estrogen-dependent gene expression" XP_017790745.1 9 Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation" XP_017798986.1 42 Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5693607;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-9609690;Reactome: R-HSA-427359;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-5250924;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-73728;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-110328;Reactome: R-HSA-2559586;Reactome: R-HSA-2299718;Reactome: R-HSA-3214815;Reactome: R-HSA-5693571;Reactome: R-HSA-3214841;Reactome: R-HSA-8939236;Reactome: R-HSA-8936459;Reactome: R-HSA-3214842;Reactome: R-HSA-110331;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-73772;Reactome: R-HSA-5625886;Reactome: R-HSA-912446;Reactome: R-HSA-2559580;Reactome: R-HSA-427389;Reactome: R-HSA-171306;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-110330;Reactome: R-HSA-5617472;Reactome: R-HSA-427413 "Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Processing of DNA double-strand break ends";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"HCMV Early Events";"SIRT1 negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"B-WICH complex positively regulates rRNA expression";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase I Promoter Opening";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Condensation of Prophase Chromosomes";"HDACs deacetylate histones";"Nonhomologous End-Joining (NHEJ)";"PKMTs methylate histone lysines";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"HDMs demethylate histones";"Cleavage of the damaged purine";"DNA methylation";"HCMV Late Events";"RNA Polymerase I Promoter Escape";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Meiotic recombination";"Oxidative Stress Induced Senescence";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Packaging Of Telomere Ends";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Recognition and association of DNA glycosylase with site containing an affected purine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression" XP_017788253.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017796639.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017788014.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017797674.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017794701.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_017787780.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434 "Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017791975.1 8 KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1 "Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis" XP_017792244.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_017796882.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_017791804.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7587 "Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)" XP_017788629.1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism" XP_017792311.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017792769.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465;Reactome: R-HSA-1660499 "T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane" XP_017789591.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400 "Macroautophagy";"AKT phosphorylates targets in the cytosol";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer" XP_017787794.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017794877.1 5 MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" XP_017794291.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;Reactome: R-HSA-3214847 "Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"HATs acetylate histones" XP_017790809.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017792329.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" XP_017793684.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017789468.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-381183;Reactome: R-HSA-114608;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-381042 "Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression" XP_017793529.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017798073.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017787727.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-9033241 "Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Peroxisomal protein import" XP_017787665.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017795966.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_017795777.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_017789646.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017792353.1 57 Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577 "Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21" XP_017788813.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017793484.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_017787447.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_017789009.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_017791657.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_017789138.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017794128.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017787585.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017791499.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_017788325.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_017794871.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017795282.1 57 Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949 "Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin" XP_017797699.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357 "Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1" XP_017799016.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_017789154.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-4615885 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"SUMOylation of DNA replication proteins" XP_017794876.1 5 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)" XP_017798451.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017799407.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017791557.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017797754.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_017791984.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_017795570.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_017791458.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790300.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017791837.1 11 MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-2029485 "2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Role of phospholipids in phagocytosis" XP_017792451.1 17 Reactome: R-HSA-200425;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1 "Carnitine metabolism";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Glyoxylate assimilation";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Pyruvate metabolism";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" XP_017796065.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017790989.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017794528.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017790595.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017795558.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170 "Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions" XP_017791826.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" XP_017798593.1 10 Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1 "Ub-specific processing proteases";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"HATs acetylate histones";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"mTOR signaling pathway" XP_017795124.1 8 KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Galactose metabolism" XP_017797803.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017793723.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017788960.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017799003.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-69273;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "HuR (ELAVL1) binds and stabilizes mRNA";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017799039.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017799560.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017795481.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827 "Regulation of RUNX2 expression and activity";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"UCH proteinases";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex" XP_017797743.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" XP_017799232.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017795463.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017790646.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_017790756.1 5 MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_017790599.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_017793527.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017793857.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_017795942.1 7 MetaCyc: PWY-7158;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1 "L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism" XP_017791530.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-881907;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events" XP_017794085.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017797839.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_017794086.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_017788230.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017792375.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017792664.1 9 MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Inositol phosphate metabolism";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule" XP_017797102.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017795478.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017787859.1 13 MetaCyc: PWY-7118;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7857;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1 "Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Pyruvate metabolism";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Ethanol oxidation";"Adlupulone and adhumulone biosynthesis";"Propanoate metabolism";"Glycolysis / Gluconeogenesis" XP_017791977.1 8 Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1 "Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis" XP_017797271.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811434 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017796913.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017789455.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017797960.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-3249367 "STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines" XP_017787746.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_017794130.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_017794523.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017793113.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017789460.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017791974.1 8 KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1 "Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_017798466.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_017790424.1 18 Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-112382 "Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex" XP_017794602.1 7 Reactome: R-HSA-1483166;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4 "Synthesis of PA";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PG";"Glycerophospholipid metabolism" XP_017791449.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676 "Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle" XP_017797588.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017798094.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_017795465.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017795305.1 8 MetaCyc: PWY-5154;MetaCyc: PWY-4983;MetaCyc: PWY-5;Reactome: R-HSA-70635;KEGG: 00250+6.3.4.5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-7400 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Canavanine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)" XP_017790581.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria" XP_017788605.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017789967.1 9 Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166 "Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"G1/S-Specific Transcription";"DNA replication initiation";"Polymerase switching";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate" XP_017791261.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_017791042.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_017795337.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_017798284.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017796171.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_017794778.1 18 MetaCyc: PWY-5913;MetaCyc: PWY-6642;MetaCyc: PWY-7383;KEGG: 00710+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7117;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Carbon fixation in photosynthetic organisms";"Isoquinoline alkaloid biosynthesis";"Sulfolactate degradation III";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism" XP_017790145.1 6 MetaCyc: PWY-6749;MetaCyc: PWY-5514;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906 "CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation" XP_017793777.1 4 Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_017797174.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017788168.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_017788212.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017798249.1 3 KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859 "Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade" XP_017799270.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Regulation of PTEN stability and activity" XP_017795540.1 10 MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-7909 "Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations II (plants)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)" XP_017797962.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017792302.1 2 Reactome: R-HSA-1433559;Reactome: R-HSA-8951664 "Regulation of KIT signaling";"Neddylation" XP_017790562.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_017793266.1 5 KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403 "Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling" XP_017789572.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_017788548.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017798635.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017789650.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571 "mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation" XP_017795974.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017787743.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_017788818.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017799214.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_017791264.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017792219.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017795283.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017798374.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017798039.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_017796988.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017789945.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017790319.1 6 Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902 "Downregulation of ERBB2 signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity" XP_017787690.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_017789870.1 33 Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-69202;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-6782135 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER" XP_017787473.1 24 Reactome: R-HSA-392170;Reactome: R-HSA-500657;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-418597;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-8964616 "ADP signalling through P2Y purinoceptor 12";"Presynaptic function of Kainate receptors";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"G alpha (z) signalling events";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"G beta:gamma signalling through CDC42" XP_017790432.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_017788269.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017789299.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017796147.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_017791171.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_017791887.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017788746.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017791668.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017791503.1 6 KEGG: 04070+3.1.3.36;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-1855204 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol" XP_017795205.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082 "Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_017788322.1 5 Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+4.2.1.109 "Formation of apoptosome";"Regulation of the apoptosome activity";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_017792256.1 8 Reactome: R-HSA-70635;MetaCyc: PWY-5;MetaCyc: PWY-5154;MetaCyc: PWY-4983;KEGG: 00250+4.3.2.1;KEGG: 00220+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-7400 "Urea cycle";"Canavanine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)" XP_017793079.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017788377.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_017794315.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017788243.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017791544.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_017794554.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017798900.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_017795406.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_017797801.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017791870.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017791177.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_017787915.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017796407.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017789292.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017792362.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" XP_017799573.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017795163.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017791290.1 7 KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017796530.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017790339.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_017792235.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017797618.1 13 MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_017789148.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_017795058.1 26 Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate IQGAPs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017795461.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017796019.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017796717.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017790150.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017795273.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017797107.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017795237.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017789709.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_017794439.1 12 KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-383280;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097 "mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Nuclear Receptor transcription pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway" XP_017795715.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_017797170.1 4 Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590 "Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling" XP_017788363.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_017793153.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017789041.1 6 Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7077;KEGG: 00052+3.5.1.25 "Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetyl-D-galactosamine degradation";"Galactose metabolism" XP_017790928.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017791888.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017794496.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017789337.1 56 Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481 "Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints" XP_017794455.1 30 Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-2564830;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167246 "RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript" XP_017789458.1 5 MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Neutrophil degranulation" XP_017796572.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017787560.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017796645.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_017792804.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017791987.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_017798506.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_017797230.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017795157.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017789314.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017790161.1 19 KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7227;Reactome: R-HSA-380270;MetaCyc: PWY-7205;MetaCyc: PWY-7222;Reactome: R-HSA-380320;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7220 "Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"CMP phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_017798592.1 10 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;Reactome: R-HSA-5689880;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722 "Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"HATs acetylate histones";"Ub-specific processing proteases";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex" XP_017788641.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017796006.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_017789388.1 5 Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;Reactome: R-HSA-6798695;MetaCyc: PWY-7180;MetaCyc: PWY-8060 "Pentose phosphate pathway";"Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I" XP_017794815.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_017793033.1 10 KEGG: 04151+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05170+2.7.1.153;KEGG: 05163+2.7.1.153 "PI3K-Akt signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system";"mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Human papillomavirus infection";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_017798205.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017794280.1 6 Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66 "Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_017797857.1 4 MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_017791180.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_017797778.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017791655.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794236.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017795193.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_017793408.1 29 Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-75955;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73863 "Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Elongation";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination" XP_017796946.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017790929.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017792948.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_017796014.1 5 Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017797770.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017787398.1 9 Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11 "G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Inositol phosphate metabolism" XP_017797982.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER" XP_017797821.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-176034;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Interactions of Tat with host cellular proteins";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_017791945.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017789538.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017790320.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017792427.1 3 KEGG: 00790+1.1.1.153;Reactome: R-HSA-1474151;Reactome: R-HSA-203615 "Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation" XP_017799323.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017788030.1 12 Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980 "RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination" XP_017792637.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_017787451.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017787761.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017791146.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017789294.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017790443.1 6 Reactome: R-HSA-2046106;Reactome: R-HSA-9603798;Reactome: R-HSA-2046105;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-390247 "alpha-linolenic acid (ALA) metabolism";"Class I peroxisomal membrane protein import";"Linoleic acid (LA) metabolism";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids" XP_017793231.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017794352.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017788094.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017798712.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017788180.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017795658.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_017793202.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis" XP_017792039.1 6 Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Photosynthesis";"Cristae formation" XP_017794437.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017792962.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017795754.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_017795991.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_017791941.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_017789734.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_017788862.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017799144.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017789935.1 5 Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation" XP_017797506.1 4 KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_017791859.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_017797854.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_017790934.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017796738.1 8 Reactome: R-HSA-2022377;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949 "Metabolism of Angiotensinogen to Angiotensins";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA" XP_017799285.1 6 Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_017791877.1 26 Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-389977 "Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Post-chaperonin tubulin folding pathway" XP_017788770.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_017792620.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_017795423.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_017792282.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_017797765.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017797052.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017792683.1 13 MetaCyc: PWY-7709;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-7410;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7102;MetaCyc: PWY-7659 "(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis" XP_017791226.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017795945.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_017787828.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582 "Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)" XP_017793798.1 4 Reactome: R-HSA-189483;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937 "Heme degradation";"Heme degradation I";"Porphyrin and chlorophyll metabolism";"Iron uptake and transport" XP_017789993.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017795825.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017792550.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415 "Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling" XP_017792071.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2468052 "SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Establishment of Sister Chromatid Cohesion" XP_017793791.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017797070.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_017792513.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_017792148.1 19 Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-5626467;Reactome: R-HSA-525793;Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-5663213;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505 "Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"RHO GTPases activate IQGAPs";"Myogenesis";"MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"Rho GTPase cycle";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"RHO GTPases Activate WASPs and WAVEs";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_017795208.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279 "Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)" XP_017790765.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017797520.1 10 Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-163680 "Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity" XP_017794151.1 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism" XP_017789742.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017796896.1 9 MetaCyc: PWY-7533;Reactome: R-HSA-156590;MetaCyc: PWY-6842;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18 "Gliotoxin biosynthesis";"Glutathione conjugation";"Glutathione-mediated detoxification II";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism" XP_017787442.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017796707.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_017797306.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-8061 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification II" XP_017791196.1 5 KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660499;MetaCyc: PWY-6368 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation" XP_017788959.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_017799531.1 10 KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5357905;Reactome: R-HSA-5357956;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1 "T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis" XP_017796845.1 15 Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-8004 "Glycolysis";"Glycolysis / Gluconeogenesis";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I" XP_017792842.1 57 Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257 "NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN" XP_017787517.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017795935.1 7 Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134 "Phenylalanine metabolism";"Phenylketonuria";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV" XP_017791057.1 5 Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630222 "Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding" XP_017796201.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017787527.1 6 MetaCyc: PWY-7285;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6785470 "Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion" XP_017793985.1 6 Reactome: R-HSA-1483166;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-163560;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118 "Synthesis of PA";"Glycerol degradation I";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle" XP_017799020.1 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606 "TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_017789278.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017796321.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017789297.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017795152.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_017799330.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017787482.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017795310.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017789897.1 31 MetaCyc: PWY-6519;Reactome: R-HSA-163765;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-5147;MetaCyc: PWY-7664;MetaCyc: PWY-7388;Reactome: R-HSA-199220;Reactome: R-HSA-75105;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-5142;MetaCyc: PWY-6113;MetaCyc: PWY-7723;MetaCyc: PWY-5994;MetaCyc: PWY-5973;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-6282;MetaCyc: PWY-5989;MetaCyc: PWY-5367;MetaCyc: PWY-4381;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-8047 "8-amino-7-oxononanoate biosynthesis I";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"";"Oleate biosynthesis I (plants)";"Oleate biosynthesis IV (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Biotin metabolism";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Superpathway of mycolate biosynthesis";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Stearate biosynthesis II (bacteria and plants)";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis";"Bryostatin biosynthesis" XP_017789656.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017792335.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017787689.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017792157.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017794263.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017793093.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017793549.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_017798044.1 12 KEGG: 00520+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Galactose metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)" XP_017798458.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017793873.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_017798527.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_017789330.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017796503.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_017796076.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017794591.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017788518.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017797748.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_017791867.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_017791143.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_017788900.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_017789585.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_017790933.1 15 Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends" XP_017791479.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017790844.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017794850.1 7 MetaCyc: PWY-7238;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-70221 "Sucrose biosynthesis II";"Neutrophil degranulation";"Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation II";"Starch degradation V";"Glycogen breakdown (glycogenolysis)" XP_017791951.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017788984.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_017794810.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017791265.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_017791329.1 3 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017799567.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017790635.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)" XP_017797676.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017793806.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_017792741.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017799355.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017796539.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_017794367.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_017791976.1 8 KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_017788671.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017793065.1 30 Reactome: R-HSA-198323;Reactome: R-HSA-8941332;Reactome: R-HSA-1358803;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-198693;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-69202;Reactome: R-HSA-5628897;Reactome: R-HSA-389513;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-392451;Reactome: R-HSA-111447;Reactome: R-HSA-8876198;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-69656;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-199418;Reactome: R-HSA-8948751;Reactome: R-HSA-5674400;Reactome: R-HSA-6804759;Reactome: R-HSA-9634638 "AKT phosphorylates targets in the cytosol";"RUNX2 regulates genes involved in cell migration";"Downregulation of ERBB2:ERBB3 signaling";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PIP3 activates AKT signaling";"AKT phosphorylates targets in the nucleus";"Thermogenesis";"Regulation of TP53 Activity through Acetylation";"Cyclin E associated events during G1/S transition";"TP53 Regulates Metabolic Genes";"CTLA4 inhibitory signaling";"mTOR signaling pathway";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"G beta:gamma signalling through PI3Kgamma";"Activation of BAD and translocation to mitochondria";"RAB GEFs exchange GTP for GDP on RABs";"Human cytomegalovirus infection";"Human papillomavirus infection";"Regulation of localization of FOXO transcription factors";"Cyclin A:Cdk2-associated events at S phase entry";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AKT-mediated inactivation of FOXO1A";"Negative regulation of the PI3K/AKT network";"Regulation of PTEN stability and activity";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Activity through Association with Co-factors";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_017797739.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_017787537.1 25 Reactome: R-HSA-380270;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Recruitment of mitotic centrosome proteins and complexes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017799322.1 19 Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-182971;Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-525793;Reactome: R-HSA-5626467;Reactome: R-HSA-389359;Reactome: R-HSA-983231 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"EGFR downregulation";"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"Rho GTPase cycle";"MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"Myogenesis";"RHO GTPases activate IQGAPs";"CD28 dependent Vav1 pathway";"Factors involved in megakaryocyte development and platelet production" XP_017792165.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017792000.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_017790121.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464 "Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins" XP_017792428.1 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_017797802.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017789099.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017792635.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017798423.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis" XP_017798476.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017795453.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017793426.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017798587.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017793009.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_017793457.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017797850.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017794979.1 11 MetaCyc: PWY-7821;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6596;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7185;MetaCyc: PWY-6608;MetaCyc: PWY-6606 "Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II" XP_017795039.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_017793443.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-9010553;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768 "GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Regulation of expression of SLITs and ROBOs";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_017791444.1 2 Reactome: R-HSA-4641262;Reactome: R-HSA-196299 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade" XP_017791506.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_017792961.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168271 "SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus" XP_017793006.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017790480.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017795908.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724 "mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription" XP_017795954.1 6 KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;MetaCyc: PWY-8010;Reactome: R-HSA-977347 "Methane metabolism";"Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis" XP_017787499.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_017793331.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017789276.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464 "Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins" XP_017799306.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017792224.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017788793.1 4 Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;MetaCyc: PWY-7250 "Molybdenum cofactor biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis" XP_017795040.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320 "Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Anchoring fibril formation" XP_017789256.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017795217.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017791767.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_017798928.1 8 Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Recycling pathway of L1";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_017791566.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_017791500.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_017799228.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_017787402.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017794865.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_017793230.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_017798969.1 5 KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-7536;MetaCyc: PWY-5189 "Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" XP_017794893.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017795489.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017794714.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017798340.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_017790386.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017789913.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017791582.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017799243.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_017795263.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017794449.1 9 MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-6703;MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-5663 "Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I" XP_017789300.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017791289.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017791075.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017790143.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_017789415.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017789040.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017789419.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903 "Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy" XP_017798358.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017789423.1 7 KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121 "Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" XP_017798548.1 20 Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616 "Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_017797205.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017793355.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788 "TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_017799202.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_017790232.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_017787669.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017794874.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017788774.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577 "Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of DVL";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21" XP_017790304.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017787449.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_017790926.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017790845.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_017797238.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673001 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF/MAP kinase cascade" XP_017791256.1 14 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-1632852;Reactome: R-HSA-2467813;Reactome: R-HSA-5620924;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Macroautophagy";"Separation of Sister Chromatids";"Intraflagellar transport";"Aggrephagy";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017793960.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017797071.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_017791125.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017795394.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_017790831.1 5 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation" XP_017799137.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_017798945.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017797353.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017793918.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017794717.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_017799009.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017792995.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017799139.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation" XP_017797521.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_017789536.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_017798726.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_017792206.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_017793866.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017788440.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017796656.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_017795476.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017799149.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_017797200.1 16 Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-167287;Reactome: R-HSA-180585 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G" XP_017791081.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_017793211.1 9 Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-381340 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_017790151.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757 "HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation" XP_017794225.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017788579.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_017791467.1 13 Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-7254;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2 "Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes" XP_017792568.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_017797265.1 5 KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16 "Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism" XP_017797759.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_017793937.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_017794699.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017798148.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_017787641.1 8 Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis" XP_017798743.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017795160.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017790960.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_017791411.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21 "Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism" XP_017793499.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_017797910.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis" XP_017792538.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_017792832.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_017789020.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017787808.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017796016.1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate" XP_017787450.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017798517.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017796481.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017794485.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_017787433.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_017797635.1 11 Reactome: R-HSA-1632852;Reactome: R-HSA-168138;Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;MetaCyc: PWY-6352;Reactome: R-HSA-5668599;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-109704 "Macroautophagy";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"PI3K Cascade" XP_017787549.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017799082.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_017787541.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_017796023.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" XP_017792477.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017795319.1 14 Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-6969;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00650+1.3.5.1 "Respiratory electron transport";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Butanoate metabolism" XP_017793506.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017793969.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017799360.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_017797542.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017792450.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_017798137.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017791760.1 22 MetaCyc: PWY-7053;MetaCyc: PWY-6433;MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7606;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7592;MetaCyc: PWY-7601;MetaCyc: PWY-7728;MetaCyc: PWY-6598;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-5080;MetaCyc: PWY-7726 "Docosahexaenoate biosynthesis I (lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_017791906.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017794275.1 6 Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_017787467.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017796742.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_017789162.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_017798835.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_017788608.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017788644.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017798556.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_017790625.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017788296.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_017793115.1 28 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-5696395;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-5358606;Reactome: R-HSA-69166;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-5656169 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"Dual incision in TC-NER";"HSF1 activation";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"Formation of Incision Complex in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Removal of the Flap Intermediate";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis" XP_017787913.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_017793523.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_017791550.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017795656.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017787543.1 6 MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017787844.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation" XP_017798525.1 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" XP_017796517.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017798710.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_017790213.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Protein ubiquitination";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017799350.1 16 Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-912631;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557;Reactome: R-HSA-512988 "G alpha (q) signalling events";"Interleukin-7 signaling";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"PIP3 activates AKT signaling";"RET signaling";"Regulation of signaling by CBL";"Rho GTPase cycle";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT";"Interleukin-3, Interleukin-5 and GM-CSF signaling" XP_017787565.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017794522.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_017797703.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017798279.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017794234.1 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_017787833.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017794946.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_017789336.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_017794820.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_017793887.1 24 Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"RHO GTPases activate IQGAPs";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_017787663.1 13 Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-3000171 "Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"ECM proteoglycans";"Signaling by PDGF";"Collagen chain trimerization";"Collagen degradation";"NCAM1 interactions";"Integrin cell surface interactions";"Extracellular matrix organization";"Anchoring fibril formation";"Non-integrin membrane-ECM interactions" XP_017795123.1 8 KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1 "Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_017798879.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_017797311.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_017793594.1 2 Reactome: R-HSA-162791;Reactome: R-HSA-189085 "Attachment of GPI anchor to uPAR";"Digestion of dietary carbohydrate" XP_017792169.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017795883.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017795197.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017795389.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_017797860.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017791243.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017792756.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_017789550.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_017798735.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017789539.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_017794661.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017789868.1 14 Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-174411 "Polymerase switching";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere" XP_017792279.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017788571.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017796614.1 1 Reactome: R-HSA-419771 "Opsins" XP_017798245.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017795735.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_017792802.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_017792468.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_017792630.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017798011.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017793986.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017787858.1 13 MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;Reactome: R-HSA-71384;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108 "Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Ethanol oxidation";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Pyruvate metabolism";"Methane metabolism";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V" XP_017798440.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017798676.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017787519.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017793064.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_017792870.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017792417.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461 "Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation" XP_017791436.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328 "TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_017789965.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-166208 "Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTORC1-mediated signalling" XP_017796739.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_017794926.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017787476.1 11 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-5689880 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases" XP_017798638.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_017787687.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017790614.1 7 MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445 "Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation" XP_017796408.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" XP_017789738.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_017788417.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017796015.1 5 Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_017798048.1 12 MetaCyc: PWY-3801;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9 "Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism" XP_017797949.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_017791186.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_017798090.1 179 Reactome: R-HSA-180585;Reactome: R-HSA-450321;Reactome: R-HSA-9013507;Reactome: R-HSA-2559580;Reactome: R-HSA-5357905;Reactome: R-HSA-5696395;Reactome: R-HSA-5684264;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-2559585;Reactome: R-HSA-6781827;Reactome: R-HSA-5610785;Reactome: R-HSA-8866652;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-5205685;Reactome: R-HSA-917729;Reactome: R-HSA-209543;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-532668;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5668541;Reactome: R-HSA-975957;Reactome: R-HSA-5607764;Reactome: R-HSA-72706;Reactome: R-HSA-69541;Reactome: R-HSA-2565942;Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-5654726;Reactome: R-HSA-9645460;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-5654727;Reactome: R-HSA-179409;Reactome: R-HSA-5655862;Reactome: R-HSA-5689896;Reactome: R-HSA-9613829;Reactome: R-HSA-8941858;Reactome: R-HSA-3769402;Reactome: R-HSA-6804756;Reactome: R-HSA-174154;Reactome: R-HSA-975144;Reactome: R-HSA-6804757;Reactome: R-HSA-6783310;Reactome: R-HSA-5656169;Reactome: R-HSA-2173788;Reactome: R-HSA-1236382;Reactome: R-HSA-192823;Reactome: R-HSA-4641263;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-5675482;Reactome: R-HSA-450408;Reactome: R-HSA-936440;Reactome: R-HSA-937042;Reactome: R-HSA-182971;Reactome: R-HSA-174490;Reactome: R-HSA-1253288;Reactome: R-HSA-9637628;Reactome: R-HSA-1169408;Reactome: R-HSA-3134975;Reactome: R-HSA-5607761;Reactome: R-HSA-5654732;Reactome: R-HSA-2173795;Reactome: R-HSA-917937;Reactome: R-HSA-5689901;Reactome: R-HSA-1295596;Reactome: R-HSA-382556;Reactome: R-HSA-6782210;Reactome: R-HSA-6807004;Reactome: R-HSA-2672351;Reactome: R-HSA-5696394;Reactome: R-HSA-349425;Reactome: R-HSA-2871837;Reactome: R-HSA-937039;Reactome: R-HSA-9014325;Reactome: R-HSA-9615710;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-8875360;Reactome: R-HSA-2691232;Reactome: R-HSA-450302;Reactome: R-HSA-1236974;Reactome: R-HSA-5685942;Reactome: R-HSA-5689877;Reactome: R-HSA-205043;Reactome: R-HSA-187577;Reactome: R-HSA-5656121;Reactome: R-HSA-5357956;Reactome: R-HSA-9633012;Reactome: R-HSA-1358803;Reactome: R-HSA-3785653;Reactome: R-HSA-2173791;Reactome: R-HSA-5654733;Reactome: R-HSA-975163;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-975110;Reactome: R-HSA-5610780;Reactome: R-HSA-8849469;Reactome: R-HSA-175474;Reactome: R-HSA-9636383;Reactome: R-HSA-2894862;Reactome: R-HSA-110312;Reactome: R-HSA-72764;Reactome: R-HSA-168928;Reactome: R-HSA-2559582;Reactome: R-HSA-4641257;Reactome: R-HSA-5693607;Reactome: R-HSA-8876493;Reactome: R-HSA-2122948;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-174048;Reactome: R-HSA-8866654;Reactome: R-HSA-4608870;Reactome: R-HSA-901032;Reactome: R-HSA-2644606;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-2122947;Reactome: R-HSA-209560;Reactome: R-HSA-6804760;Reactome: R-HSA-5610783;Reactome: R-HSA-8856825;Reactome: R-HSA-5696397;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9013973;Reactome: R-HSA-5689603;Reactome: R-HSA-9033241;Reactome: R-HSA-937041;Reactome: R-HSA-68949;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-8948747;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-937072;Reactome: R-HSA-202424;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-5676590;Reactome: R-HSA-6791226;Reactome: R-HSA-201681;Reactome: R-HSA-156902;Reactome: R-HSA-2173796;Reactome: R-HSA-110314;Reactome: R-HSA-8856828;Reactome: R-HSA-168927;Reactome: R-HSA-174113;Reactome: R-HSA-5675221;Reactome: R-HSA-180534;Reactome: R-HSA-5693565;Reactome: R-HSA-445989;Reactome: R-HSA-211733;Reactome: R-HSA-9646399;Reactome: R-HSA-912631;Reactome: R-HSA-5362768;Reactome: R-HSA-8863795;Reactome: R-HSA-6782135;Reactome: R-HSA-3322077;Reactome: R-HSA-2979096;Reactome: R-HSA-9020702;Reactome: R-HSA-162588;Reactome: R-HSA-168638;Reactome: R-HSA-8939902;Reactome: R-HSA-936964;Reactome: R-HSA-1799339;Reactome: R-HSA-400253 "Vif-mediated degradation of APOBEC3G";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Oxidative Stress Induced Senescence";"Regulation of TNFR1 signaling";"Formation of Incision Complex in GG-NER";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Oncogene Induced Senescence";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"GLI3 is processed to GLI3R by the proteasome";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Degradation of DVL";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Pink/Parkin Mediated Mitophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"p75NTR recruits signalling complexes";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"TNFR2 non-canonical NF-kB pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"CLEC7A (Dectin-1) signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Stabilization of p53";"Regulation of PLK1 Activity at G2/M Transition";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR1 signaling";"Alpha-protein kinase 1 signaling pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of FGFR2 signaling";"APC-Cdc20 mediated degradation of Nek2A";"Translesion synthesis by POLK";"Ovarian tumor domain proteases";"Chaperone Mediated Autophagy";"Regulation of RUNX3 expression and activity";"Deactivation of the beta-catenin transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"APC/C:Cdc20 mediated degradation of Securin";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of TP53 Degradation";"Fanconi Anemia Pathway";"Termination of translesion DNA synthesis";"Downregulation of TGF-beta receptor signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Viral mRNA Translation";"Regulation of FZD by ubiquitination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Regulation of necroptotic cell death";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Negative regulators of DDX58/IFIH1 signaling";"IRAK2 mediated activation of TAK1 complex";"EGFR downregulation";"Membrane binding and targetting of GAG proteins";"Downregulation of ERBB4 signaling";"Modulation by Mtb of host immune system";"ISG15 antiviral mechanism";"Regulation of innate immune responses to cytosolic DNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of FGFR3 signaling";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Iron uptake and transport";"Metalloprotease DUBs";"Spry regulation of FGF signaling";"ABC-family proteins mediated transport";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Negative regulation of MET activity";"Stimuli-sensing channels";"DNA Damage Recognition in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"FCERI mediated NF-kB activation";"IRAK1 recruits IKK complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Late endosomal microautophagy";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"activated TAK1 mediates p38 MAPK activation";"ER-Phagosome pathway";"HDR through Homologous Recombination (HRR)";"Josephin domain DUBs";"NRIF signals cell death from the nucleus";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion synthesis by POLI";"TNFR1-induced NFkappaB signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Downregulation of ERBB2:ERBB3 signaling";"Myoclonic epilepsy of Lafora";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Negative regulation of FGFR4 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Degradation of GLI1 by the proteasome";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Assembly Of The HIV Virion";"Prevention of phagosomal-lysosomal fusion";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Translesion synthesis by REV1";"Eukaryotic Translation Termination";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Senescence-Associated Secretory Phenotype (SASP)";"Degradation of AXIN";"Processing of DNA double-strand break ends";"InlA-mediated entry of Listeria monocytogenes into host cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"E3 ubiquitin ligases ubiquitinate target proteins";"Asymmetric localization of PCP proteins";"ER Quality Control Compartment (ERQC)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOTCH1 Intracellular Domain Regulates Transcription";"NF-kB is activated and signals survival";"Regulation of TP53 Activity through Methylation";"Degradation of GLI2 by the proteasome";"Cargo recognition for clathrin-mediated endocytosis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"TICAM1-dependent activation of IRF3/IRF7";"UCH proteinases";"Peroxisomal protein import";"IKK complex recruitment mediated by RIP1";"Orc1 removal from chromatin";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Regulation of PTEN localization";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Downstream TCR signaling";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"NIK-->noncanonical NF-kB signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"TCF dependent signaling in response to WNT";"Peptide chain elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Recognition of DNA damage by PCNA-containing replication complex";"Clathrin-mediated endocytosis";"TICAM1, RIP1-mediated IKK complex recruitment";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of MAPK pathway";"Vpu mediated degradation of CD4";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Aggrephagy";"Regulation of signaling by CBL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2 signaling";"Dual incision in TC-NER";"Glycogen synthesis";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Interleukin-1 signaling";"Budding and maturation of HIV virion";"NOD1/2 Signaling Pathway";"Regulation of RUNX2 expression and activity";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"SRP-dependent cotranslational protein targeting to membrane";"Circadian Clock" XP_017797489.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_017792569.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017797787.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017791305.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017791653.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017789697.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017792523.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_017796797.1 56 Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184 "Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Orc1 removal from chromatin";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_017789570.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017797269.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_017794758.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_017795968.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_017792688.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017797944.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_017795458.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017799512.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017796042.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017789681.1 14 MetaCyc: PWY-5497;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2201;KEGG: 00680+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00670+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-1622 "Purine nucleobases degradation II (anaerobic)";"Cyanoamino acid metabolism";"Folate transformations I";"Methane metabolism";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Metabolism of folate and pterines";"Folate transformations II (plants)";"One carbon pool by folate";"Folate polyglutamylation";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation I";"Formaldehyde assimilation I (serine pathway)" XP_017788539.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_017794889.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017798409.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_017791584.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017796680.1 26 Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-6807878 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Mitotic Prometaphase";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-mediated anterograde transport" XP_017793454.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058 "Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_017797622.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017798383.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_017789348.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017790895.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753 "Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions" XP_017788837.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017795634.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_017790761.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-6596 "Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Adenosine nucleotides degradation I" XP_017789228.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017796843.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_017792678.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017799129.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_017792947.1 8 Reactome: R-HSA-6791461;Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00710+5.3.1.6;MetaCyc: PWY-1861;KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996 "RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P" XP_017796413.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" XP_017788016.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_017791094.1 3 Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168 "SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017791651.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_017792611.1 11 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" XP_017798933.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_017788345.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017794474.1 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268 "Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017790212.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017791602.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Aggrephagy";"Separation of Sister Chromatids";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_017797983.1 5 MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine catabolism";"Pyrimidine salvage" XP_017798175.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_017792020.1 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" XP_017794489.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017790755.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017793330.1 8 MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-7181;Reactome: R-HSA-73614;Reactome: R-HSA-6798695;MetaCyc: PWY-7199 "Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage" XP_017787847.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_017794990.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-349425 "G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1" XP_017790340.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_017791084.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_017793750.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017790815.1 7 KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;MetaCyc: PWY-2541;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;MetaCyc: PWY-7154;Reactome: R-HSA-191273 "Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Phytosterol biosynthesis (plants)";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Ergosterol biosynthesis II";"Cholesterol biosynthesis" XP_017793832.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_017792702.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_017790754.1 29 Reactome: R-HSA-5358565;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-110312 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"HSF1 activation";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Translesion synthesis by REV1" XP_017796732.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017798406.1 10 KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00562+5.3.1.1 "Fructose and mannose metabolism";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Inositol phosphate metabolism" XP_017798609.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017799208.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017790893.1 14 MetaCyc: PWY-5695;MetaCyc: PWY-6607;Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6538;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6999;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00232+1.17.3.2;MetaCyc: PWY-6596;Reactome: R-HSA-8851680;MetaCyc: PWY-5497;KEGG: 00983+1.17.3.2 "Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation I";"Purine catabolism";"Purine metabolism";"Caffeine degradation III (bacteria, via demethylation)";"Purine metabolism";"Theophylline degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Caffeine metabolism";"Adenosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Purine nucleobases degradation II (anaerobic)";"Drug metabolism - other enzymes" XP_017795113.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-983168 "APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017796587.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017799578.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017797624.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017797023.1 6 MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017797080.1 6 MetaCyc: PWY-7111;MetaCyc: PWY-5101;KEGG: 00290+4.2.1.9;MetaCyc: PWY-5104;MetaCyc: PWY-5103;KEGG: 00770+4.2.1.9 "Pyruvate fermentation to isobutanol (engineered)";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III";"Pantothenate and CoA biosynthesis" XP_017798869.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017790096.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" XP_017793180.1 12 KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-1042;MetaCyc: PWY-6142 "Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017796020.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_017793493.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_017787536.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017792378.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994 "PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017791330.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_017792154.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation" XP_017792193.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_017795184.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017789084.1 7 KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7176 "Drug metabolism - other enzymes";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis" XP_017797158.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017787556.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017794652.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017799029.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_017798425.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_017788343.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017792079.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017799084.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_017799181.1 5 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_017787682.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017793152.1 33 Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-2500257;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-68877;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9648025;Reactome: R-HSA-9610379 "tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Mitotic Prometaphase";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"EML4 and NUDC in mitotic spindle formation";"HCMV Late Events" XP_017796274.1 5 Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695 "Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation" XP_017797875.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828 "InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis" XP_017792377.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017793495.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_017791791.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017790572.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" XP_017798588.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_017791967.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_017788590.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017792199.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017789135.1 3 MetaCyc: PWY-7210;KEGG: 00240+3.5.4.12;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017791969.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_017798038.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_017791654.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_017796801.1 13 MetaCyc: PWY-6613;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-5030 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate polyglutamylation";"L-histidine degradation III" XP_017799401.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_017792614.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017790917.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017794923.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017792440.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017787441.1 5 KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00680+1.1.1.95 "Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Methane metabolism" XP_017799570.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017798322.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_017797042.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017790636.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017796903.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017795822.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017792286.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_017797742.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017790588.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017789152.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017787926.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017789359.1 5 Reactome: R-HSA-450321;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway" XP_017789750.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017792287.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_017790343.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_017798117.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_017792021.1 3 KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1 "Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway" XP_017794383.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017797548.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_017796134.1 17 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-1834949 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Cytosolic sensors of pathogen-associated DNA" XP_017787875.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_017789164.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_017790874.1 3 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation" XP_017791271.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_017798183.1 16 Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat" XP_017799331.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017798265.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_017792933.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017797902.1 5 MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;Reactome: R-HSA-193048;Reactome: R-HSA-4755579 "Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ" XP_017798659.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017794530.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017788983.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_017795957.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_017789655.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017787427.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_017797356.1 11 Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_017795880.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_017798554.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_017789699.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017794472.1 8 Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity" XP_017787457.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_017797496.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017787988.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017790414.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017796948.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017787445.1 5 MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7210 "UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Neutrophil degranulation";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_017799566.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_017798338.1 7 MetaCyc: PWY-7782;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886 "Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Choline biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis" XP_017795666.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_017788439.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017793575.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-389957 "Transcriptional Regulation by E2F6";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_017796898.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-6837;Reactome: R-HSA-9033241 "(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import" XP_017798979.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017794989.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_017796393.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017789074.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017789966.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_017792903.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017796588.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32 "Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" XP_017792284.1 6 Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-110373;Reactome: R-HSA-110362;Reactome: R-HSA-110357 "PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1" XP_017793235.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017798167.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis" XP_017796144.1 7 Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72662 "Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S" XP_017794278.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66 "3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_017798216.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_017791713.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017790547.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017790855.1 7 Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105 "Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation" XP_017793675.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_017797516.1 12 Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1169408;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"ISG15 antiviral mechanism";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017787472.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_017788126.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017797876.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_017792818.1 60 KEGG: 00592+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;Reactome: R-HSA-77310;MetaCyc: PWY-5109;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7007;Reactome: R-HSA-77350;MetaCyc: PWY-7656;KEGG: 00280+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00720+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-6944;KEGG: 00362+4.2.1.17;MetaCyc: PWY-7606;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-7726;Reactome: R-HSA-77348;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6435;Reactome: R-HSA-77285;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7779;KEGG: 00410+4.2.1.17;KEGG: 00310+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7401;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;Reactome: R-HSA-77346;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00650+4.2.1.17;KEGG: 00640+4.2.1.17;Reactome: R-HSA-77305;MetaCyc: PWY-6883;MetaCyc: PWY-5136;Reactome: R-HSA-1482798;Reactome: R-HSA-77288;MetaCyc: PWY-7094;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17 "alpha-Linolenic acid metabolism";"Fatty acid elongation";"Carbon fixation pathways in prokaryotes";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fermentation to 2-methylbutanoate";"Phenylalanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Toluene degradation";"Methyl ketone biosynthesis (engineered)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Spodoptera littoralis pheromone biosynthesis";"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Aminobenzoate degradation";"Carbon fixation pathways in prokaryotes";"Caprolactam degradation";"Benzoyl-coa degradation I (aerobic)";"Androstenedione degradation";"Benzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"Glutaryl-coa degradation";"Tryptophan metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Limonene and pinene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Benzoate degradation";"Butanoate metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl tert-butyl ether degradation";"beta-Alanine metabolism";"Lysine degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Pyruvate fermentation to hexanol (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Fatty acid degradation";"Geraniol degradation";"Tryptophan metabolism";"2-methylpropene degradation";"Butanoate metabolism";"Propanoate metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Acyl chain remodeling of CL";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fatty acid salvage";"Pyruvate fermentation to butanol I";"Caprolactam degradation" XP_017795295.1 14 KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00020+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-6969;Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Citrate cycle (TCA cycle)";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_017797889.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_017798005.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_017799146.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017791615.1 4 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism" XP_017793126.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_017788036.1 2 KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_017789086.1 7 KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Drug metabolism - other enzymes";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017792151.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_017790988.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017791450.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736 "Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors" XP_017788441.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017789895.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017795818.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017798414.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017799055.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017795484.1 10 KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6365;MetaCyc: PWY-6554;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.159;Reactome: R-HSA-1855204;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6366;Reactome: R-HSA-983231 "Inositol phosphate metabolism";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production" XP_017792028.1 24 Reactome: R-HSA-202424;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-5218921;KEGG: 05170+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;Reactome: R-HSA-392451;Reactome: R-HSA-389357;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5607764;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1257604 "Downstream TCR signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"VEGFR2 mediated cell proliferation";"Human immunodeficiency virus 1 infection";"GPVI-mediated activation cascade";"PI3K-Akt signaling pathway";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"G beta:gamma signalling through PI3Kgamma";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"Regulation of TP53 Degradation";"CLEC7A (Dectin-1) signaling";"RSK activation";"Thermogenesis";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PIP3 activates AKT signaling" XP_017788665.1 8 Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6" XP_017795242.1 12 Reactome: R-HSA-196780;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;KEGG: 00670+2.1.2.9;Reactome: R-HSA-73817;MetaCyc: PWY-6277 "Biotin transport and metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_017790592.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017797890.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017790227.1 11 MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2 "Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrogen metabolism" XP_017790616.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824 "Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis" XP_017795344.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_017799058.1 8 MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-1989781 "Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression" XP_017791942.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017794657.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017795720.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_017794613.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017793876.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-191859 "PPARA activates gene expression";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly" XP_017794763.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017798570.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017788298.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_017790860.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017795162.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017799111.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017790785.1 3 Reactome: R-HSA-111471;Reactome: R-HSA-9645722;Reactome: R-HSA-140837 "Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation" XP_017791556.1 4 KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III" XP_017795269.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_017797363.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_017795221.1 14 MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-6969;MetaCyc: PWY-7254;Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1 "Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)" XP_017795642.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_017799203.1 56 Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902 "CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity" XP_017798242.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_017798186.1 16 Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-1234176 "HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_017799599.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_017798780.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_017790164.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" XP_017789517.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017797063.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_017794967.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_017796478.1 3 MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_017799081.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_017794898.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017788128.1 5 Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5610787 "BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog 'off' state" XP_017797132.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017796055.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017792997.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017792718.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_017791886.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017790883.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017792536.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017787593.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" XP_017794529.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_017799429.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017787448.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017787438.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_017791281.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017798700.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_017788821.1 4 KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20 "Cysteine and methionine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism" XP_017794129.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_017788532.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_017797027.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" XP_017790730.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017798511.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017797777.1 5 Reactome: R-HSA-9646399;Reactome: R-HSA-983168;Reactome: R-HSA-5205685;Reactome: R-HSA-977225;Reactome: R-HSA-5689877 "Aggrephagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation";"Josephin domain DUBs" XP_017789422.1 3 KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5 "Styrene degradation";"Tyrosine catabolism";"Tyrosine metabolism" XP_017787480.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_017792529.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_017791426.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_017787615.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_017794519.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_017790447.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_017793998.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017794153.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017789792.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_017797844.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_017792358.1 33 Reactome: R-HSA-8939236;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-69231;Reactome: R-HSA-6781823;Reactome: R-HSA-112382;Reactome: R-HSA-69656;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-69273;Reactome: R-HSA-73776;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-6782135 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Cyclin D associated events in G1";"Formation of TC-NER Pre-Incision Complex";"Formation of RNA Pol II elongation complex";"Cyclin A:Cdk2-associated events at S phase entry";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER" XP_017798077.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017798964.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017790525.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)" XP_017787520.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_017787860.1 14 MetaCyc: PWY-6886;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-1042;MetaCyc: PWY-6142 "1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017790262.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017788342.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017793522.1 13 MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)" XP_017790682.1 57 Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-532668;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541 "Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway" XP_017794826.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_017791940.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994 "Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_017789515.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_017797019.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017794544.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_017792721.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017792150.1 19 Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-983231;Reactome: R-HSA-389359;Reactome: R-HSA-5626467;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-3928662;Reactome: R-HSA-194840;Reactome: R-HSA-5625970 "G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"EGFR downregulation";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production";"CD28 dependent Vav1 pathway";"RHO GTPases activate IQGAPs";"Myogenesis";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"EPHB-mediated forward signaling";"Rho GTPase cycle";"RHO GTPases activate KTN1" XP_017799062.1 7 Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-8856828;KEGG: 04070+3.1.3.36 "Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Clathrin-mediated endocytosis";"Phosphatidylinositol signaling system" XP_017797030.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017788385.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017789811.1 2 Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis" XP_017796980.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017787356.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_017789114.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" XP_017788607.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017794336.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017789097.1 44 Reactome: R-HSA-5675221;Reactome: R-HSA-456926;Reactome: R-HSA-5654732;Reactome: R-HSA-2559582;Reactome: R-HSA-198753;Reactome: R-HSA-6802955;Reactome: R-HSA-1295596;Reactome: R-HSA-5654726;Reactome: R-HSA-6802948;Reactome: R-HSA-881907;Reactome: R-HSA-444257;Reactome: R-HSA-74749;Reactome: R-HSA-112409;Reactome: R-HSA-879415;Reactome: R-HSA-170968;Reactome: R-HSA-6811558;Reactome: R-HSA-9627069;Reactome: R-HSA-5654727;Reactome: R-HSA-8943724;Reactome: R-HSA-6802946;Reactome: R-HSA-2871796;Reactome: R-HSA-5674135;Reactome: R-HSA-9635465;Reactome: R-HSA-5663213;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2029482;Reactome: R-HSA-5673001;Reactome: R-HSA-445144;Reactome: R-HSA-2559580;Reactome: R-HSA-9649948;Reactome: R-HSA-450341;Reactome: R-HSA-5674499;Reactome: R-HSA-6802952;Reactome: R-HSA-8940973;Reactome: R-HSA-8939211;Reactome: R-HSA-2559585;Reactome: R-HSA-5654733;Reactome: R-HSA-162658;Reactome: R-HSA-9634638;Reactome: R-HSA-5668599;Reactome: R-HSA-202670;Reactome: R-HSA-3371453;Reactome: R-HSA-375165;Reactome: R-HSA-982772 "Negative regulation of MAPK pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Negative regulation of FGFR3 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"ERK/MAPK targets";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Spry regulation of FGF signaling";"Negative regulation of FGFR1 signaling";"Signaling by high-kinase activity BRAF mutants";"Gastrin-CREB signalling pathway via PKC and MAPK";"RSK activation";"Signal attenuation";"RAF-independent MAPK1/3 activation";"Advanced glycosylation endproduct receptor signaling";"Frs2-mediated activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of the apoptosome activity";"Negative regulation of FGFR2 signaling";"Regulation of PTEN gene transcription";"Signaling by moderate kinase activity BRAF mutants";"FCERI mediated MAPK activation";"MAP2K and MAPK activation";"Suppression of apoptosis";"RHO GTPases Activate WASPs and WAVEs";"mTOR signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"RAF/MAP kinase cascade";"Signal transduction by L1";"Oxidative Stress Induced Senescence";"Signaling downstream of RAS mutants";"Activation of the AP-1 family of transcription factors";"Negative feedback regulation of MAPK pathway";"Signaling by BRAF and RAF fusions";"RUNX2 regulates osteoblast differentiation";"ESR-mediated signaling";"Oncogene Induced Senescence";"Negative regulation of FGFR4 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate NADPH Oxidases";"ERKs are inactivated";"Regulation of HSF1-mediated heat shock response";"NCAM signaling for neurite out-growth";"Growth hormone receptor signaling" XP_017790271.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_017793170.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017796398.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017799345.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017795985.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_017796003.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_017797099.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017789631.1 7 Reactome: R-HSA-3214842;Reactome: R-HSA-983231;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-5625886 "HDMs demethylate histones";"Factors involved in megakaryocyte development and platelet production";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_017796555.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex" XP_017796784.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017792562.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017793913.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017799458.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017794044.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_017795404.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017790074.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_017790097.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017795091.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017796715.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_017795596.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017797662.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017790267.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880 "Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Orc1 removal from chromatin";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases" XP_017793735.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017795034.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_017789644.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017788466.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017799477.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017789923.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_017799000.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017798652.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017794997.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_017796618.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017797239.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-936837;Reactome: R-HSA-399719 "Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion transport by P-type ATPases";"Trafficking of AMPA receptors" XP_017788767.1 11 KEGG: 00240+6.3.5.5;Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;MetaCyc: PWY-7791 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"UMP biosynthesis III" XP_017797865.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" XP_017789607.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757 "Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation" XP_017798362.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-5080 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I" XP_017790814.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)" XP_017789332.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_017789082.1 12 KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-6708;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-6978;MetaCyc: PWY-5855;MetaCyc: PWY-5873;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5871 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)" XP_017794479.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_017790510.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939 "POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)" XP_017788361.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_017789683.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017791865.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_017796146.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017787759.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017794615.1 13 MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-9027277;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491 "2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"Erythropoietin activates Phospholipase C gamma (PLCG)";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"DAP12 signaling" XP_017791913.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017795010.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_017799042.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017799528.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_017799343.1 7 KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4 "Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Butanoate metabolism";"Peroxisomal protein import";"Synthesis of Ketone Bodies";"Geraniol degradation" XP_017788299.1 5 Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex" XP_017790071.1 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" XP_017793339.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497 "Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017795345.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017792384.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_017792204.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017798441.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_017798182.1 16 Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-6796648 "Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"TP53 Regulates Transcription of DNA Repair Genes" XP_017790009.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_017788384.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017797940.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017799236.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017789367.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695 "Signal transduction by L1";"Receptor Mediated Mitophagy";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation" XP_017797237.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-442982 "Assembly and cell surface presentation of NMDA receptors";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Ras activation upon Ca2+ influx through NMDA receptor" XP_017795624.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-9013973 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7" XP_017789784.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017796872.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" XP_017790701.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017790275.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017788612.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017795312.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_017791249.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_017797428.1 7 Reactome: R-HSA-70268;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_017796841.1 15 MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6886;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40 "Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Purine metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_017790832.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_017796288.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_017796740.1 7 Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;MetaCyc: PWY-7511 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination" XP_017789163.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_017793706.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_017788250.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_017796528.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_017795233.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017796819.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Fanconi Anemia Pathway" XP_017799159.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017789616.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_017788313.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017789693.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_017794087.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_017794616.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" XP_017790223.1 57 Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-174154;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-983168;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553 "Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Orc1 removal from chromatin";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdc20 mediated degradation of Securin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs" XP_017787466.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017793447.1 5 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_017792993.1 3 Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062 "HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis" XP_017789571.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017798312.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017787726.1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241 "Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"Peroxisomal protein import" XP_017792858.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_017788847.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017798456.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017794882.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_017797118.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_017788323.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017789042.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017798664.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017789416.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017794448.1 9 MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-5663;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-6703 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis" XP_017790604.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_017797599.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017788781.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_017796595.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017788367.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017796438.1 6 Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16 "Circadian Clock";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation" XP_017792606.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_017797531.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_017795118.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017798459.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017799336.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway" XP_017796585.1 9 Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827 "Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex" XP_017789405.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796 "GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation" XP_017794665.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017789463.1 15 Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-176412;Reactome: R-HSA-174178 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_017793439.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events" XP_017794100.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_017787382.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017789986.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017788554.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_017794549.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_017799127.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_017790292.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_017788321.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017794885.1 7 Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1" XP_017788437.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017793327.1 20 Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-6804756;Reactome: R-HSA-176187 "HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress" XP_017796610.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017790500.1 10 Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-381042;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9648895;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PERK regulates gene expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK1 (HRI) to heme deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017790586.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017793901.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Intraflagellar transport";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017788634.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_017793649.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017787810.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_017798427.1 4 Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583 "Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)" XP_017799518.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_017795762.1 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_017793392.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017793919.1 16 Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-201722;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-5693568;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends" XP_017794715.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017795165.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017793104.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_017793629.1 57 Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-174113;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-9010553;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-174184;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of expression of SLITs and ROBOs";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Degradation of GLI1 by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Orc1 removal from chromatin";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_017793357.1 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788 "TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_017788643.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017797616.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017790684.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017798145.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-975957 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017798017.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017790993.1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_017796423.1 3 Reactome: R-HSA-8955332;Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Carboxyterminal post-translational modifications of tubulin";"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_017798138.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017788645.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017794779.1 18 MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00220+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism";"Arginine and proline metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_017790395.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017793796.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_017790966.1 11 Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-174430 "Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation" XP_017794483.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-975634;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-8964046 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Platelet sensitization by LDL";"LDL remodeling";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Retinoid metabolism and transport";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Scavenging by Class A Receptors";"Chylomicron assembly";"VLDL clearance" XP_017788393.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_017797096.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017799403.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_017791233.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-983168 "APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017795789.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017787563.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017792894.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_017791406.1 3 KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle" XP_017798397.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017790028.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-432040 "Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"PKA activation";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_017791671.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399 "Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_017790156.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017798396.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_017792648.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_017788598.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_017792025.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017787477.1 11 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-5689880 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Ub-specific processing proteases" XP_017799562.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017795215.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_017795226.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017792412.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" XP_017791922.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation" XP_017791366.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017793055.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017789252.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964 "Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_017798455.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017795775.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_017788267.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017790611.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_017795575.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_017799606.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017793651.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017794091.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_017791086.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_017789632.1 22 MetaCyc: PWY-7049;MetaCyc: PWY-7602;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7726;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7606;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7728;MetaCyc: PWY-6958;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_017788690.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_017793373.1 11 MetaCyc: PWY-7124;MetaCyc: PWY-6549;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7254;Reactome: R-HSA-71403;MetaCyc: PWY-7268 "Ethylene biosynthesis V (engineered)";"L-glutamine biosynthesis III";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_017791372.1 6 MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017798102.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017792812.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_017795502.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017798111.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_017788320.1 5 Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000 "Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation" XP_017793550.1 13 MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7198;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Drug metabolism - other enzymes" XP_017789443.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017792787.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017790335.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification" XP_017793038.1 7 Reactome: R-HSA-203927;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-6784531 "MicroRNA (miRNA) biogenesis";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus" XP_017797456.1 5 Reactome: R-HSA-380994;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012 "ATF4 activates genes in response to endoplasmic reticulum stress";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_017788429.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017789406.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_017798859.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017794873.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_017792308.1 5 Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897 "TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes" XP_017787381.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017798555.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_017791363.1 17 MetaCyc: PWY-7179;MetaCyc: PWY-6620;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-5695 "Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Guanosine nucleotides degradation III";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Purine catabolism";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation" XP_017787481.1 4 Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440 "Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" XP_017791408.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017795507.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017798240.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation" XP_017791232.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_017790450.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_017793141.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017794004.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017790504.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_017792016.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017795046.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017796649.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_017797321.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_017792217.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017793678.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_017792167.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017797358.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_017792729.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_017790068.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017790113.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017796129.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_017787498.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017797172.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_017799309.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017797097.1 10 MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7187;MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;KEGG: 00240+2.1.1.45;Reactome: R-HSA-69205;MetaCyc: PWY-7199 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine metabolism";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage" XP_017787651.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_017789352.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017794237.1 10 Reactome: R-HSA-975634;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-977225;Reactome: R-HSA-2453902;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;Reactome: R-HSA-3000171;MetaCyc: PWY-5691 "Retinoid metabolism and transport";"Urate conversion to allantoin III";"Purine metabolism";"Amyloid fiber formation";"The canonical retinoid cycle in rods (twilight vision)";"Neutrophil degranulation";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I" XP_017798360.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017791178.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_017798243.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_017793282.1 12 KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00030+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13 "Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Methane metabolism" XP_017794147.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017794331.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_017799026.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_017797066.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398 "Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway" XP_017797800.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017795415.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_017791071.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017790644.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017792605.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_017791585.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_017792907.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_017795809.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_017792814.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017798730.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017792754.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6554;MetaCyc: PWY-6361;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158 "Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" XP_017789482.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_017795235.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017796531.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_017799396.1 10 KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41 "Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_017789864.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017794071.1 5 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation" XP_017793646.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017796103.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017795601.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_017792770.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_017791217.1 12 MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5856 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_017791766.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_017798474.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017798463.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017788114.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017796869.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017795824.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017798166.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_017793307.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017793420.1 27 Reactome: R-HSA-72163;Reactome: R-HSA-159227;Reactome: R-HSA-77595;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-975956;Reactome: R-HSA-73856;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72203;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-191859;Reactome: R-HSA-9010553;Reactome: R-HSA-6807505;Reactome: R-HSA-72086;Reactome: R-HSA-159230;Reactome: R-HSA-167242 "mRNA Splicing - Major Pathway";"Transport of the SLBP independent Mature mRNA";"Processing of Intronless Pre-mRNAs";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Processing of Capped Intron-Containing Pre-mRNA";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"snRNP Assembly";"Regulation of expression of SLITs and ROBOs";"RNA polymerase II transcribes snRNA genes";"mRNA Capping";"Transport of the SLBP Dependant Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_017796781.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017794892.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017795904.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017792064.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017796694.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_017788089.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017787742.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_017792699.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_017797878.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_017797846.1 5 Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ophthalmate biosynthesis" XP_017788214.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_017793717.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017787485.1 7 Reactome: R-HSA-3214847;Reactome: R-HSA-171319;Reactome: R-HSA-5689603;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-5689880;Reactome: R-HSA-606279 "HATs acetylate histones";"Telomere Extension By Telomerase";"UCH proteinases";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_017798444.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_017797914.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_017797840.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_017797826.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017795452.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_017796627.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017787923.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_017793169.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_017792541.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_017792862.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017790732.1 5 Reactome: R-HSA-381038;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-5358346;Reactome: R-HSA-901032 "XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)" XP_017792938.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017791145.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017793218.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017794048.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852 "Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Macroautophagy" XP_017787999.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_017793428.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017794811.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_017799596.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_017790485.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_017788172.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_017790728.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_017795816.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017792682.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017797805.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_017793268.1 4 Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497 "Attenuation phase";"Estrogen-dependent gene expression";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_017791307.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_017791333.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_017798263.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-983168;Reactome: R-HSA-8866427 "Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation" XP_017792731.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017791694.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_017790120.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017797929.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_017789648.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_017793548.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_017790958.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_017795556.1 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_017795790.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_017797838.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017795397.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017799221.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279 "Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)" XP_017796535.1 19 Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-381426 "VLDL clearance";"Scavenging by Class A Receptors";"Chylomicron assembly";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"LDL remodeling";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Chylomicron clearance";"Scavenging by Class B Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_017792331.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_017790008.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017798018.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_017792173.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017788420.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017789176.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017796947.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017794257.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_017798526.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_017794470.1 1 MetaCyc: PWY-6938 "NADH repair" XP_017789215.1 4 Reactome: R-HSA-4570464;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-9610379 "SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"HCMV Late Events" XP_017797244.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946 "Signaling downstream of RAS mutants";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"RAF activation";"Signaling by moderate kinase activity BRAF mutants" XP_017788621.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017793693.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-156590;Reactome: R-HSA-204174 "Tyrosine catabolism";"Glutathione conjugation";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_017797696.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_017793822.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_017799298.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017798043.1 12 KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9 "Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism" XP_017790927.1 10 MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2024096 "Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Other glycan degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Neutrophil degranulation";"HS-GAG degradation" XP_017790274.1 3 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN" XP_017788872.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_017789706.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017798909.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017793016.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_017798454.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017792355.1 7 MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;KEGG: 00230+3.5.2.5 "UMP biosynthesis II";"UMP biosynthesis III";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Pyrimidine metabolism";"UMP biosynthesis I";"Purine metabolism" XP_017794853.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_017792112.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis" XP_017798235.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_017790560.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_017799234.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017797825.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017794769.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017793477.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7836;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism" XP_017790681.1 18 Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4 "Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism" XP_017790048.1 9 Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475 "HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_017795473.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-983231 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production" XP_017792047.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_017790807.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_017796277.1 5 Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Dual incision in TC-NER" XP_017796949.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_017791423.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_017797882.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_017791553.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" XP_017791403.1 5 Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21 "Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_017799563.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017798624.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_017795234.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017790376.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017790272.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_017799572.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_017799091.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017795111.1 16 Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-983168 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017792694.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017793388.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_017790491.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_017793223.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_017787954.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017795224.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017788259.1 7 Reactome: R-HSA-140837;Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-381426 "Intrinsic Pathway of Fibrin Clot Formation";"Platelet degranulation";"Post-translational protein phosphorylation";"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_017795986.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017794368.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_017791168.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_017787411.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_017791034.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_017788235.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_017798416.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_017794821.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017798732.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_017799603.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_017798634.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_017791253.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_017794838.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017793542.1 20 MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-5136;KEGG: 00071+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid degradation";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism" XP_017789954.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017788129.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" XP_017796226.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_017789160.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_017788392.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017796711.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_017792530.1 4 Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-9615017 "AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_017793920.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_017790387.1 18 MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Synthesis of PA";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism" XP_017787548.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_017796644.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017788130.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_017799523.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017796272.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017798551.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017792272.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017790410.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017791058.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017790380.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_017799200.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_017791560.1 12 KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6683;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00920+2.7.1.25;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4 "Selenocompound metabolism";"Sulfite oxidation III";"Assimilatory sulfate reduction III";"Selenate reduction";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Sulfur metabolism" XP_017793654.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_017795099.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" XP_017791787.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017788062.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_017795146.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_017794102.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" XP_017798881.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_017791371.1 17 KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-5695;MetaCyc: PWY-5532;MetaCyc: PWY-7179;MetaCyc: PWY-6620;Reactome: R-HSA-74217;MetaCyc: PWY-6608;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1 "Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage V";"Neutrophil degranulation";"Purine catabolism";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Purine deoxyribonucleosides degradation I";"Guanine and guanosine salvage";"Purine salvage";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Purine metabolism" XP_017798191.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_017796561.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters" XP_017798172.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" XP_017798841.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_017798889.1 14 MetaCyc: PWY-8053;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416 "Anandamide biosynthesis II";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_017793728.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_017798384.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_017797971.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_017794387.1 13 KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism" XP_017794605.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017796471.1 5 Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471 "VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" XP_017787452.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017798504.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844 "Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_017794782.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_017789368.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243 "Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Signal transduction by L1";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017797131.1 5 MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-7902 "CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Synthesis of PA";"Glucosylglycerol biosynthesis" XP_017794556.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017794920.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017796681.1 26 Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467 "Kinesins";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Cilium Assembly";"HCMV Early Events";"RHO GTPases activate IQGAPs" XP_017798803.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_017789298.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_017798460.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017796215.1 16 MetaCyc: PWY-6886;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-7218 "1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" XP_017795309.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_017796458.1 5 MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis" XP_017798598.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_017796793.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017795784.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017797928.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_017798343.1 40 Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-6803529;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-5617472;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-8851708 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"FGFR2 alternative splicing";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcriptional regulation by small RNAs";"mRNA Capping";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Signaling by FGFR2 IIIa TM" XP_017788037.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_017797782.1 7 Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23 "Pyrimidine biosynthesis";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine metabolism" XP_017788725.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_017791142.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017791613.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852 "Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy" XP_017788167.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017792301.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017788318.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948 "Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants" XP_017798665.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_017790918.1 10 KEGG: 00410+2.6.1.19;MetaCyc: PWY-4321;MetaCyc: PWY-6535;MetaCyc: PWY-6536;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-6537;Reactome: R-HSA-916853 "beta-Alanine metabolism";"L-glutamate degradation IV";"4-aminobutanoate degradation I";"4-aminobutanoate degradation III";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation V";"4-aminobutanoate degradation II";"Degradation of GABA" XP_017797614.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_017793280.1 7 KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625 "Glycerophospholipid metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)" XP_017795721.1 13 Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902 "Keratan sulfate degradation";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)" XP_017791387.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017799539.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_017791279.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017789574.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_017797753.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_017789100.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017795641.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017787470.1 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;MetaCyc: PWY-2221 "Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_017799126.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_017791952.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_017790632.1 52 Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-349425;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-5610785 "Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"UCH proteinases";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RAS by GAPs";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"GLI3 is processed to GLI3R by the proteasome" XP_017793379.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017793644.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017793270.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_017795946.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_017798100.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_017798936.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_017795244.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017796777.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_017793090.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017792158.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_017791110.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_017797702.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017790741.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_017790659.1 4 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" XP_017788618.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017794902.1 7 Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017798052.1 12 MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Galactose metabolism";"Sucrose biosynthesis II";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism" XP_017793423.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_017798062.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017796844.1 15 MetaCyc: PWY-6886;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-1042 "1-butanol autotrophic biosynthesis (engineered)";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Rubisco shunt";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)" XP_017788544.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_017788424.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017787558.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_017798223.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_017799216.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_017793279.1 7 MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-6352;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11 "Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"3-phosphoinositide biosynthesis";"Synthesis of PI";"Phosphatidylinositol signaling system" XP_017798880.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_017796500.1 29 Reactome: R-HSA-5696400;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-73772;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-167172 "Dual Incision in GG-NER";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome" XP_017788543.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" XP_017795229.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-1799339 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane" XP_017796367.1 58 Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-1234176;Reactome: R-HSA-174184;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5610783;Reactome: R-HSA-195253;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5689901;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-983168;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-382556 "Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of GLI1 by the proteasome";"Neddylation";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog 'on' state";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of GLI2 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Metalloprotease DUBs";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport" XP_017794452.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_017792214.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_017790251.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_017787613.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_017794738.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_017787538.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_017792540.1 6 MetaCyc: PWY-6908;MetaCyc: PWY-6898;MetaCyc: PWY-6907;MetaCyc: PWY-7356;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2 "Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism" XP_017792319.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_017795275.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_017790842.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017794194.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017799554.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017788825.1 4 Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_017797579.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_017798085.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_017795733.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017796653.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017791184.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017795216.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017787664.1 13 Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-2214320;Reactome: R-HSA-216083;Reactome: R-HSA-419037;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"Anchoring fibril formation";"Integrin cell surface interactions";"NCAM1 interactions";"Collagen chain trimerization";"Collagen degradation";"ECM proteoglycans";"Signaling by PDGF";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Laminin interactions" XP_017787469.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017789823.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_017792305.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-165054 "HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA" XP_017793683.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017787574.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017790887.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017789584.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_017795776.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_017797035.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_017797746.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_017791123.1 6 Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins" XP_017789132.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_017798390.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017799286.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_017796114.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017793617.1 6 Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"ESR-mediated signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_017795339.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017798499.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_017798422.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017798580.1 7 Reactome: R-HSA-163210;MetaCyc: PWY-7980;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Oxidative phosphorylation";"Photosynthesis";"Cristae formation" XP_017794098.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_017792338.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-2995383;Reactome: R-HSA-4419969 "Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina" XP_017789976.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_017797110.1 17 Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_017799555.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017798224.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_017787683.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017796194.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_017794446.1 3 MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_017799312.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_017790011.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_017792400.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_017788577.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_017789449.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_017793810.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_017796577.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_017796881.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_017793954.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_017795577.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_017788053.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_017796156.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_017794670.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_017795071.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_017791308.1 4 Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27 "Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Valine, leucine and isoleucine degradation";"Propanoate metabolism" XP_017791624.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_017793627.1 11 MetaCyc: PWY-6859;MetaCyc: PWY-7391;MetaCyc: PWY-7560;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2 "All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)";"Methylerythritol phosphate pathway II";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_017788702.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-389661 "Mitochondrial Fatty Acid Beta-Oxidation";"Respiratory electron transport";"Complex I biogenesis";"Glyoxylate metabolism and glycine degradation" XP_017792792.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation" XP_017795159.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_017798489.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_017791283.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017795219.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_017798244.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017794497.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" XP_017789789.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_017791311.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_017794097.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_017795967.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_017798185.1 16 Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-8951664;Reactome: R-HSA-167246 "Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript" XP_017798025.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_017795798.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_017795047.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_017790703.1 10 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"RSK activation";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" XP_017792758.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_017792975.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_017794903.1 10 MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587 "CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)" XP_017793394.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_017791163.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017795147.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_017787680.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017787707.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_017791362.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_017794796.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017792439.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017793585.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_017788614.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017795468.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017787709.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017789295.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" XP_017796582.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_017798168.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis" XP_017787982.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017797952.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017791471.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_017795959.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_017792788.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017789662.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379 "Late endosomal microautophagy";"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events" XP_017796370.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017799303.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_017788599.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_017792533.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_017799556.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_017796602.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_017791287.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017794159.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_017791138.1 4 Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6 "Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_017791513.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972 "Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" XP_017795166.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_017788662.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_017791398.1 56 Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-5668541;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-2467813;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-1234176;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-8939236 "Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"TNFR2 non-canonical NF-kB pathway";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Separation of Sister Chromatids";"Degradation of GLI1 by the proteasome";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Orc1 removal from chromatin";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog 'on' state";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_017795827.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_017796172.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_017789979.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111464 "Respiratory electron transport";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_017793778.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_017799256.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_017790889.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_017796403.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_017798378.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_017795232.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_017793518.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_017798824.1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-6142 "Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_017796275.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_017789158.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_017793839.1 4 KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4 "Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_017790452.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_017787814.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_017794242.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_017789964.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_017799456.1 4 KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_017796039.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_017796699.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017792575.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_017788575.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_017795239.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_017791778.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_017799128.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_017799040.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_017788075.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_017798457.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_017796093.1 5 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_017798096.1 24 Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-983189 "RHO GTPases activate IQGAPs";"Cilium Assembly";"HCMV Early Events";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"Recycling pathway of L1";"Kinesins" XP_017788442.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_017794901.1 11 Reactome: R-HSA-388841;Reactome: R-HSA-391160;Reactome: R-HSA-9008059;Reactome: R-HSA-909733;Reactome: R-HSA-389948;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-877312;Reactome: R-HSA-912694;Reactome: R-HSA-210990;Reactome: R-HSA-432142 "Costimulation by the CD28 family";"Signal regulatory protein family interactions";"Interleukin-37 signaling";"Interferon alpha/beta signaling";"PD-1 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Regulation of IFNG signaling";"Regulation of IFNA signaling";"PECAM1 interactions";"Platelet sensitization by LDL" XP_017789950.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_017789131.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_017799311.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_017790466.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-180746 "SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"ISG15 antiviral mechanism";"HCMV Early Events";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein" XP_017788740.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_017789048.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_017792393.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_017788841.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_017788324.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_017799289.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_017794770.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_017788981.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_017793254.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_017794527.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_017793485.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_017797736.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_017789306.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017794476.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism" XP_017796691.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_017787547.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_017787357.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_017788303.1 11 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"Myogenesis" XP_017794594.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017798121.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_017791440.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_017794583.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_017792385.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_017790907.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_017793182.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_017798445.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_017789627.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_017788146.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_017789645.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_017795509.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_017790286.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_017798854.1 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_017796765.1 10 Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880;Reactome: R-HSA-432720 "Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis" XP_017798800.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_017788990.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation" XP_017788735.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_017789586.1 7 KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;Reactome: R-HSA-446205 "Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose" XP_017790361.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_017788083.1 12 KEGG: 04150+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1839117 "mTOR signaling pathway";"Signaling by FGFR1 in disease";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling by cytosolic FGFR1 fusion mutants" XP_017789773.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_017797315.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic"