Accession_ID Pathway_Count Pathway_IDs Pathway_Names PCG81036.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" PCG70338.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" PCG77017.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by REV1" PCG65250.1 5 KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging" PCG71055.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG76223.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG68508.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" PCG78662.1 8 MetaCyc: PWY-6901;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;KEGG: 00270+1.1.1.27 "Superpathway of glucose and xylose degradation";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Cysteine and methionine metabolism" PCG69081.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" PCG72532.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" PCG62568.1 4 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" PCG76487.1 24 KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-202424 "Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Thermogenesis";"Regulation of TP53 Degradation";"Human papillomavirus infection";"CLEC7A (Dectin-1) signaling";"Integrin signaling";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"RHO GTPases activate PKNs";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"mTOR signaling pathway";"G beta:gamma signalling through PI3Kgamma";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling" PCG79272.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" PCG81128.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" PCG67472.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG77793.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG68853.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes" PCG69735.1 6 Reactome: R-HSA-446199;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33 "Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis" PCG72777.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG80399.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" PCG79315.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG77050.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" PCG70751.1 6 KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" PCG65576.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" PCG69595.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG71623.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" PCG74511.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG67506.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG64683.1 6 Reactome: R-HSA-69166;Reactome: R-HSA-162594;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-174437 "Removal of the Flap Intermediate";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand" PCG78171.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" PCG75884.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG80810.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69231 "G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1" PCG80062.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" PCG67894.1 15 MetaCyc: PWY-5723;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901 "Rubisco shunt";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"Purine metabolism";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation" PCG65998.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG66616.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG73498.1 4 KEGG: 00010+3.1.3.9;Reactome: R-HSA-70263;KEGG: 00500+3.1.3.9;KEGG: 00052+3.1.3.9 "Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism" PCG73888.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" PCG67753.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG65132.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG79142.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" PCG65346.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG66831.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG81024.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" PCG70412.1 7 MetaCyc: PWY-5941;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-7238 "Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Starch degradation II";"Starch degradation V";"Neutrophil degranulation";"Sucrose biosynthesis II" PCG67414.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" PCG64048.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" PCG78595.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG79803.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition" PCG77101.1 5 MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine" PCG75365.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG74704.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG79628.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" PCG74888.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" PCG63723.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" PCG70716.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" PCG71218.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" PCG74227.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG75815.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" PCG67607.1 11 MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;MetaCyc: PWY-7206 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Starch and sucrose metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation" PCG69770.1 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" PCG63537.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" PCG71402.1 14 Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-113418 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex" PCG70429.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG79782.1 56 Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562 "Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)" PCG69168.1 9 KEGG: 00564+1.1.1.8;MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Glycerol-3-phosphate shuttle" PCG80856.1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" PCG74553.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG68416.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" PCG73159.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG65431.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" PCG74594.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" PCG76861.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG66486.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" PCG80793.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG64501.1 6 MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" PCG78571.1 3 Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-5621575 "Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"CD209 (DC-SIGN) signaling" PCG71843.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG73219.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" PCG67511.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" PCG72800.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" PCG70188.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-975634 "LDL remodeling";"VLDL assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"LDL clearance";"VLDL clearance";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Retinoid metabolism and transport" PCG63733.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG80480.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG80270.1 14 Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025 "COPI-mediated anterograde transport";"Macroautophagy";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation" PCG63826.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG73267.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" PCG80726.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" PCG68752.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG69808.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG75061.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" PCG68824.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG77832.1 13 Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320 "Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Collagen chain trimerization";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"NCAM1 interactions";"Extracellular matrix organization";"Collagen degradation";"Anchoring fibril formation" PCG78238.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG63740.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG79281.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" PCG62796.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-113501 "Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Polymerase switching";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" PCG72456.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG63149.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG78048.1 24 Reactome: R-HSA-4420097;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-163560;Reactome: R-HSA-422356;Reactome: R-HSA-5610780;Reactome: R-HSA-9010642;Reactome: R-HSA-180024;Reactome: R-HSA-163358;Reactome: R-HSA-5687128;Reactome: R-HSA-9634600;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5621575;Reactome: R-HSA-8963896;Reactome: R-HSA-111931;Reactome: R-HSA-5610785;Reactome: R-HSA-8853659;Reactome: R-HSA-983231;Reactome: R-HSA-392517;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "VEGFA-VEGFR2 Pathway";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Triglyceride catabolism";"Regulation of insulin secretion";"Degradation of GLI1 by the proteasome";"ROBO receptors bind AKAP5";"DARPP-32 events";"PKA-mediated phosphorylation of key metabolic factors";"MAPK6/MAPK4 signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"mTOR signaling pathway";"CD209 (DC-SIGN) signaling";"HDL assembly";"PKA-mediated phosphorylation of CREB";"GLI3 is processed to GLI3R by the proteasome";"RET signaling";"Factors involved in megakaryocyte development and platelet production";"Rap1 signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" PCG72013.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG63977.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" PCG71311.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" PCG68709.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG73802.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG73248.1 26 Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-8852276 "RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint" PCG75488.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" PCG76932.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601 "FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" PCG80545.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" PCG79184.1 1 Reactome: R-HSA-1296061 "HCN channels" PCG65458.1 4 Reactome: R-HSA-5679001;Reactome: R-HSA-382556;Reactome: R-HSA-189483;MetaCyc: PWY-6972 "Defective ABCC2 causes Dubin-Johnson syndrome";"ABC-family proteins mediated transport";"Heme degradation";"Oleandomycin activation/inactivation" PCG71821.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" PCG78849.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG77422.1 13 Reactome: R-HSA-1855204;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-9027277;Reactome: R-HSA-202433;Reactome: R-HSA-2029485;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871809;MetaCyc: PWY-8052;Reactome: R-HSA-2871796 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Generation of second messenger molecules";"Role of phospholipids in phagocytosis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Inositol phosphate metabolism";"FCERI mediated Ca+2 mobilization";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation" PCG75693.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" PCG79328.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" PCG64863.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" PCG77747.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" PCG79801.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" PCG74271.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG76464.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-5649702;Reactome: R-HSA-110381;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939 "Gap-filling DNA repair synthesis and ligation in TC-NER";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Resolution of AP sites via the single-nucleotide replacement pathway";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)" PCG69942.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG67821.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG77795.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG72618.1 10 MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660514;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517 "3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the Golgi membrane";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Toll Like Receptor 9 (TLR9) Cascade";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane" PCG69875.1 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" PCG68411.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" PCG71185.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG70088.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG65240.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" PCG78142.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG74399.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" PCG65822.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" PCG64643.1 7 Reactome: R-HSA-196757;Reactome: R-HSA-1474151;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-6614 "Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis" PCG69816.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG78326.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG71819.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" PCG74858.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG79283.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" PCG79329.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" PCG66378.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4551638 "HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins" PCG74406.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" PCG64838.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG71958.1 5 Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" PCG80193.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" PCG75470.1 31 MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-5367;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-6113;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-8049 "Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis" PCG68239.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG76713.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" PCG71586.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG78702.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" PCG62748.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG73352.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" PCG66918.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" PCG77304.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG78369.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG69347.1 12 MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-5873;KEGG: 00130+1.14.99.60 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis" PCG78233.1 18 Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242 "RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat" PCG70598.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" PCG76618.1 57 Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Ub-specific processing proteases";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling" PCG70842.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619 "2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN" PCG63165.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5972 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" PCG78906.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG67896.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5723 "Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Rubisco shunt" PCG74656.1 5 KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3 "Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes" PCG74872.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG79231.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" PCG78527.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG77418.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" PCG72918.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" PCG78692.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685 "Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy";"Pink/Parkin Mediated Mitophagy" PCG77284.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" PCG70450.1 18 KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-6798695;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5537;Reactome: R-HSA-163765;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5172;MetaCyc: PWY-6969 "Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Neutrophil degranulation";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Acetyl-coa biosynthesis III (from citrate)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" PCG62760.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis" PCG64339.1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" PCG62702.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" PCG67329.1 56 Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837 "Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Neddylation";"FCERI mediated NF-kB activation" PCG68197.1 4 KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism" PCG64425.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" PCG78248.1 3 Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" PCG72980.1 17 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" PCG67191.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" PCG75453.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" PCG77307.1 1 Reactome: R-HSA-6805567 "Keratinization" PCG70539.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" PCG68653.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174184 "Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" PCG72351.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG64158.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis" PCG77087.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG64819.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" PCG64779.1 1 Reactome: R-HSA-525793 "Myogenesis" PCG73874.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG68864.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG63396.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG78205.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG63154.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" PCG72341.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" PCG62638.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430 "Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex" PCG76296.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" PCG70994.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG74213.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG72943.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG77507.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones" PCG62621.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG66133.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" PCG78363.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" PCG67343.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG80171.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG76481.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG64116.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG79641.1 10 Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579 "Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange" PCG67871.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG78358.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG76506.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" PCG66330.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" PCG74363.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG77812.1 4 MetaCyc: PWY-7382;MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism" PCG65152.1 14 Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200 "RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" PCG78421.1 6 MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36 "Mevalonate pathway I";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis" PCG74937.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG74585.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG75679.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" PCG73567.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG78672.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" PCG81117.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" PCG62923.1 4 Reactome: R-HSA-72731;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" PCG64893.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" PCG64568.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" PCG76944.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" PCG68449.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" PCG70915.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG62708.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" PCG78599.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" PCG72950.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG71517.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG69912.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" PCG66607.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" PCG74666.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling" PCG76833.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362277 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex" PCG70969.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" PCG72274.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" PCG72262.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG76359.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922 "Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog 'off' state";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium" PCG77866.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" PCG74647.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG70563.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" PCG74597.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG66282.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" PCG77318.1 1 Reactome: R-HSA-5689603 "UCH proteinases" PCG74524.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG78231.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097 "Activation of RAC1";"Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway" PCG64832.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" PCG76245.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG75766.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" PCG62782.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG73269.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" PCG63558.1 6 MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-622;Reactome: R-HSA-189085 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Digestion of dietary carbohydrate" PCG73832.1 5 KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983 "Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)" PCG68591.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" PCG73361.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" PCG75356.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" PCG79922.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG78281.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG77957.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG67555.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG69650.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" PCG69963.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG68244.1 8 Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Amino acids regulate mTORC1";"Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" PCG69032.1 5 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-427413 "DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression" PCG65108.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG63780.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" PCG73659.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG77375.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" PCG69653.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" PCG67992.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG62414.1 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;Reactome: R-HSA-1483166;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4 "Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Synthesis of PA";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism" PCG78168.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" PCG76293.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" PCG76715.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" PCG66278.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" PCG79417.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" PCG77203.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" PCG78504.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG77000.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG73405.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" PCG77161.1 1 Reactome: R-HSA-3295583 "TRP channels" PCG70873.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" PCG63161.1 1 Reactome: R-HSA-191859 "snRNP Assembly" PCG71174.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG75900.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG77486.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG74373.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" PCG69574.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" PCG65888.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" PCG78613.1 10 Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-2644606 "Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" PCG65644.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" PCG74002.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "Cytosolic tRNA aminoacylation";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" PCG66837.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" PCG67924.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" PCG79182.1 4 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" PCG69551.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG78882.1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" PCG78558.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG78822.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG65016.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" PCG73831.1 5 Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes" PCG67050.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG71205.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" PCG78130.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG78660.1 12 KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"mTOR signaling pathway";"Thermogenesis";"NRAGE signals death through JNK";"Human papillomavirus infection";"Rho GTPase cycle";"Relaxin signaling pathway";"G alpha (q) signalling events";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"PI3K-Akt signaling pathway" PCG73296.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" PCG68565.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" PCG78192.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG78556.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG65011.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7338 "beta-Alanine metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" PCG71486.1 3 Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271 "GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism" PCG75742.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" PCG62666.1 14 MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041 "Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis" PCG77863.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" PCG63754.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG78887.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858 "Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity" PCG79172.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG67522.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG79723.1 3 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" PCG64525.1 1 Reactome: R-HSA-156581 "Methylation" PCG72411.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG65512.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG79039.1 7 MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates" PCG78348.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" PCG66603.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG74244.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" PCG72018.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG80339.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG68321.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG67610.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG77080.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG79752.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion" PCG80438.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" PCG69414.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" PCG75509.1 18 KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416 "alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" PCG66894.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" PCG77044.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG70302.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG75006.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" PCG80395.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation" PCG79097.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" PCG62565.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins" PCG81118.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis" PCG64606.1 16 MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-7124;MetaCyc: PWY-7003;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-2221;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1042 "Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol";"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Methane metabolism";"Glycolysis IV (plant cytosol)" PCG76682.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG80336.1 3 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" PCG76178.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" PCG76319.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" PCG63137.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG76613.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" PCG67232.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG78528.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG74035.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" PCG78499.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG64511.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" PCG78913.1 8 MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217 "Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine salvage" PCG72506.1 13 KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-1722;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-6613;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-7909;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-2201 "Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"L-histidine degradation III";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate transformations I" PCG79711.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG69975.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion" PCG74378.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" PCG80134.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" PCG78406.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" PCG78391.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG73214.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG79624.1 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" PCG78598.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" PCG72703.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638 "RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" PCG72474.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527 "Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation" PCG63037.1 3 MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51 "Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation" PCG73861.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG69663.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG79319.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" PCG75088.1 10 Reactome: R-HSA-5620912;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-380259;Reactome: R-HSA-3108214;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Loss of Nlp from mitotic centrosomes";"SUMOylation of DNA damage response and repair proteins";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" PCG64225.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8951664 "Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Neddylation" PCG67398.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" PCG72328.1 4 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation" PCG62904.1 5 Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619 "Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN" PCG71011.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" PCG73487.1 10 KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41 "Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis" PCG76705.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" PCG79318.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" PCG72492.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" PCG67803.1 5 Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-381426 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" PCG66241.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG79597.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG77874.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG63080.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" PCG75448.1 18 KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;MetaCyc: PWY-5913;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1 "Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Novobiocin biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis" PCG76891.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG77630.1 10 MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484 "Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" PCG66110.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" PCG74456.1 3 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-383280 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway" PCG62960.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" PCG66680.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins" PCG74861.1 19 Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-8876725;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-3214858 "rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Protein methylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"RMTs methylate histone arginines" PCG71487.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" PCG79521.1 12 Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-205043 "Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus" PCG78832.1 5 MetaCyc: PWY-6129;Reactome: R-HSA-4755579;Reactome: R-HSA-446199;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94 "Dolichol and dolichyl phosphate biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Synthesis of Dolichyl-phosphate";"Androgen biosynthesis";"N-Glycan biosynthesis" PCG79015.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway" PCG73250.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" PCG66344.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" PCG79748.1 10 Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8934903 "WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"Receptor Mediated Mitophagy" PCG75845.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" PCG72897.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" PCG80547.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG75393.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG73454.1 5 MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981 "L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)" PCG63172.1 13 MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403 "TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)" PCG66147.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" PCG73635.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" PCG73030.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" PCG79067.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" PCG66597.1 20 Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607 "Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends" PCG74610.1 30 Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-2122947;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-917937;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-2644607;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-1170546;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-69231;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-400253;Reactome: R-HSA-2644606 "Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"NOTCH1 Intracellular Domain Regulates Transcription";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Iron uptake and transport";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Prolactin receptor signaling";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Cyclin D associated events in G1";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" PCG63445.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" PCG65302.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)" PCG70085.1 7 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG63499.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG79409.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG70769.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG72361.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG71527.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" PCG72793.1 4 MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22 "Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism" PCG79751.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion" PCG74768.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" PCG78634.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG77501.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG77745.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG75067.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" PCG62503.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG75434.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG64277.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" PCG81031.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265 "Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes" PCG68596.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" PCG80135.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" PCG67950.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" PCG79856.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" PCG66969.1 7 KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6471;Reactome: R-HSA-4549356;MetaCyc: PWY-6470;MetaCyc: PWY-5265 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)" PCG80069.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG65824.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" PCG79639.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" PCG80599.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG70044.1 7 KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36 "Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism" PCG63702.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" PCG71204.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" PCG71503.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG65565.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG69575.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" PCG70262.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" PCG62563.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG64484.1 5 Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" PCG70753.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG77660.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" PCG78856.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" PCG73917.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" PCG72737.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" PCG72470.1 5 MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism";"Galactose metabolism" PCG70446.1 5 Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3 "Pyrimidine catabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism" PCG66524.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG70127.1 14 MetaCyc: PWY-4302;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-3781 "Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Respiratory electron transport";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)" PCG68592.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" PCG77376.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" PCG66031.1 7 KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism" PCG80979.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" PCG69423.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" PCG69343.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" PCG71252.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" PCG79461.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG79953.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG79730.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-373753 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Nephrin family interactions" PCG64378.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis" PCG74912.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" PCG72841.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" PCG70530.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" PCG66393.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" PCG77461.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" PCG74648.1 6 Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.66 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" PCG70970.1 6 MetaCyc: PWY-7238;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;Reactome: R-HSA-70221;MetaCyc: PWY-5941 "Sucrose biosynthesis II";"Starch degradation III";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II" PCG62416.1 9 KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744 "Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation" PCG63294.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" PCG62443.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG67233.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG79114.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" PCG78365.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" PCG75313.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" PCG75093.1 7 Reactome: R-HSA-375276;Reactome: R-HSA-140837;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-381426 "Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation";"Platelet degranulation";"G alpha (i) signalling events";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" PCG69612.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG71714.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" PCG66263.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG68155.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" PCG67352.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation" PCG79739.1 7 Reactome: R-HSA-381070;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381033 "IRE1alpha activates chaperones";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones" PCG69845.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG65617.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" PCG72287.1 5 KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism" PCG78394.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG63852.1 14 MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" PCG79771.1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation" PCG75171.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" PCG72623.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG77109.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" PCG78076.1 6 Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796;Reactome: R-HSA-381426 "RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" PCG67199.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" PCG63866.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG69585.1 3 Reactome: R-HSA-72764;Reactome: R-HSA-156581;Reactome: R-HSA-432722 "Eukaryotic Translation Termination";"Methylation";"Golgi Associated Vesicle Biogenesis" PCG67714.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" PCG71256.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG77687.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" PCG78149.1 4 Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228 "Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix" PCG68937.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG74576.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG79512.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG75238.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG79189.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" PCG62885.1 3 Reactome: R-HSA-159740;MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90 "Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" PCG70468.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG65014.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-6837 "alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" PCG68593.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" PCG71605.1 1 Reactome: R-HSA-71288 "Creatine metabolism" PCG73351.1 5 KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" PCG75794.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" PCG76236.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" PCG76396.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG77043.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG70592.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG64655.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG68769.1 26 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint" PCG68617.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822 "Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein" PCG80637.1 10 KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Ub-specific processing proteases";"Relaxin signaling pathway" PCG78298.1 4 Reactome: R-HSA-4549349;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132 "Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" PCG72792.1 4 MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22 "Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism" PCG68466.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG80668.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG77948.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" PCG67989.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG77947.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG75901.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG71535.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" PCG74843.1 1 Reactome: R-HSA-191859 "snRNP Assembly" PCG63500.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG74857.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG78643.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG70045.1 7 KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36 "Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism" PCG64084.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG68331.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" PCG69304.1 56 Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541 "Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Interleukin-1 signaling";"Ub-specific processing proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway" PCG74566.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG71228.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG68646.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-165054 "HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA" PCG77419.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" PCG73297.1 52 Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813 "Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids" PCG78195.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG75630.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG62841.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" PCG72282.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG76299.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" PCG74253.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" PCG65817.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" PCG79727.1 9 Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5218920 "G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"Rho GTPase cycle";"NRAGE signals death through JNK";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability" PCG75220.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" PCG79213.1 1 Reactome: R-HSA-191859 "snRNP Assembly" PCG62514.1 2 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" PCG79117.1 4 MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18 "Heme degradation I";"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism" PCG70470.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG69867.1 11 MetaCyc: PWY-6607;KEGG: 00760+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6596;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-6606;MetaCyc: PWY-7185;MetaCyc: PWY-6608;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5695 "Guanosine nucleotides degradation I";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)";"Guanosine nucleotides degradation II";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation III";"Purine metabolism";"Inosine 5'-phosphate degradation" PCG64025.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" PCG79983.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG72063.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" PCG72968.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG75336.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" PCG64010.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" PCG78329.1 5 Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" PCG62634.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG79102.1 9 Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-113501 "Polymerase switching";"DNA replication initiation";"G1/S-Specific Transcription";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" PCG76224.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" PCG66276.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" PCG69274.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" PCG68142.1 56 Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949 "The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin" PCG80669.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG70950.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" PCG79853.1 14 MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-6453;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;Reactome: R-HSA-1483191 "Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PE";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC" PCG74229.1 33 Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-69656;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-69202;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-73762;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-69273;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-69231 "Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"Cyclin E associated events during G1/S transition";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin D associated events in G1" PCG71045.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG75502.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" PCG62446.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" PCG62496.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG67888.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" PCG78057.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG68122.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG63335.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-113418 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex" PCG69322.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" PCG74021.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" PCG69839.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" PCG66834.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG64940.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG80126.1 3 Reactome: R-HSA-727802;Reactome: R-HSA-5619078;Reactome: R-HSA-6787639 "Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis" PCG72359.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" PCG64938.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG74588.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG74353.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" PCG65018.1 20 MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6 "Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation" PCG67382.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG75340.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" PCG71607.1 1 Reactome: R-HSA-71288 "Creatine metabolism" PCG67790.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" PCG65930.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" PCG79419.1 4 Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156581;Reactome: R-HSA-6782315 "rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation";"tRNA modification in the nucleus and cytosol" PCG65954.1 6 MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3 "Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate" PCG76456.1 6 KEGG: 00511+3.2.1.25;Reactome: R-HSA-2160916;Reactome: R-HSA-8853383;Reactome: R-HSA-6798695;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096 "Other glycan degradation";"Hyaluronan uptake and degradation";"Lysosomal oligosaccharide catabolism";"Neutrophil degranulation";"MPS VII - Sly syndrome";"HS-GAG degradation" PCG73238.1 8 KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" PCG71489.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" PCG64460.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" PCG62766.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" PCG69803.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" PCG63703.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" PCG70581.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG75436.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG65444.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG64846.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG62567.1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" PCG73932.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG75242.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG72645.1 25 Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148 "Aggrephagy";"Gap junction assembly";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG80382.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism" PCG66088.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG77722.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" PCG78187.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" PCG70802.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG62472.1 14 MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-6886 "Rubisco shunt";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)" PCG77420.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" PCG73078.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" PCG73658.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG81056.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG79829.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG73118.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG78457.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017;Reactome: R-HSA-198693 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"AKT phosphorylates targets in the nucleus" PCG77379.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" PCG78917.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG76936.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG69592.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG73129.1 3 KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662;MetaCyc: PWY-7277 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)" PCG80167.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" PCG71511.1 8 KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5740;MetaCyc: PWY-7573;Reactome: R-HSA-6787639;MetaCyc: PWY-66;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739 "Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis" PCG79869.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG62546.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG80035.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG77644.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" PCG75637.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG72084.1 9 Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-8004 "Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I" PCG77202.1 6 Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253 "Triglyceride catabolism";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Circadian Clock" PCG74382.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG68282.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" PCG74204.1 17 KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1 "Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"Propanoate metabolism";"Carnitine metabolism";"Biotin transport and metabolism";"Pyruvate metabolism";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" PCG68067.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" PCG69558.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" PCG64827.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912399 "Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum" PCG72778.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" PCG64707.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-975957;Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-159227;Reactome: R-HSA-8851708;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-159231;Reactome: R-HSA-6803529;Reactome: R-HSA-975956;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-159236;Reactome: R-HSA-77588 "snRNP Assembly";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP independent Mature mRNA";"Signaling by FGFR2 IIIa TM";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" PCG78165.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG80560.1 4 Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism" PCG70469.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG67130.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" PCG80104.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" PCG69428.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" PCG67118.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" PCG67928.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" PCG77916.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG68488.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG78151.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" PCG80656.1 9 MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency" PCG70893.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" PCG74680.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" PCG72496.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122 "Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" PCG63969.1 3 KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Effects of PIP2 hydrolysis" PCG73800.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping" PCG80057.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" PCG67664.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" PCG63388.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG74203.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946 "Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" PCG63299.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG66164.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K Cascade" PCG66042.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG71346.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" PCG69446.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG64764.1 20 MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7007;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6 "Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation" PCG69155.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" PCG73598.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" PCG72588.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" PCG78361.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG75664.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG67087.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" PCG62566.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG67193.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" PCG80360.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG75225.1 20 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-166208;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of TP53 Degradation";"Human papillomavirus infection";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"Thermogenesis";"mTORC1-mediated signalling";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Macroautophagy" PCG69708.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" PCG69730.1 15 MetaCyc: PWY-5723;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40 "Rubisco shunt";"Entner-Doudoroff pathway I";"Purine metabolism";"Glycerol degradation to butanol";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism" PCG62709.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" PCG71727.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG64644.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" PCG78129.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG81115.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" PCG75266.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG73324.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG68995.1 2 KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" PCG62560.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG68149.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG70582.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG67460.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" PCG73929.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" PCG76966.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG74004.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG65488.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" PCG74856.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" PCG66697.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG78197.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG72628.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" PCG65104.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" PCG73541.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG74083.1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)" PCG77502.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG69019.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" PCG78557.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG71823.1 5 Reactome: R-HSA-2173789;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-917937 "TGF-beta receptor signaling activates SMADs";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"Iron uptake and transport" PCG78706.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG75014.1 16 Reactome: R-HSA-5693554;Reactome: R-HSA-9018519;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-201722;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Formation of the beta-catenin:TCF transactivating complex";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence" PCG78629.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" PCG80370.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG64505.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" PCG67192.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" PCG65425.1 4 MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975 "Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate" PCG68734.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" PCG70945.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" PCG68587.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" PCG72797.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-2467813;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-195253 "Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Separation of Sister Chromatids";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"RHO GTPases Activate Formins";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex" PCG69958.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG63451.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" PCG75504.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG76668.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway" PCG78434.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" PCG74974.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG75432.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG66165.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K Cascade" PCG64347.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" PCG76955.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" PCG68264.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" PCG74059.1 13 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3928663 "Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"Thermogenesis";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"EPHA-mediated growth cone collapse" PCG71070.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG76458.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG72001.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" PCG77717.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" PCG67197.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG73160.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG67151.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" PCG79210.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" PCG64549.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG77629.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG78435.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" PCG66559.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG64979.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" PCG77807.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG64070.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis" PCG73040.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG79632.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" PCG70885.1 8 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-380972 "mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK" PCG75659.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG80448.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" PCG65034.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" PCG76201.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG72650.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" PCG79686.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG69829.1 1 Reactome: R-HSA-400253 "Circadian Clock" PCG69712.1 7 Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;MetaCyc: PWY-5084 "Lysine catabolism";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" PCG78817.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG69888.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" PCG68676.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-445989;Reactome: R-HSA-1810476 "TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1" PCG71036.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" PCG67502.1 11 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614657 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"FOXO-mediated transcription of cell death genes" PCG72104.1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813 "Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids" PCG66413.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" PCG73694.1 4 Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841 "Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" PCG74917.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" PCG69149.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG75433.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG77396.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" PCG78754.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG71429.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" PCG70126.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" PCG78567.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG73206.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" PCG77174.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" PCG77990.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" PCG63861.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG69661.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG66346.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889 "CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes" PCG77462.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER" PCG69614.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG69074.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" PCG79656.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG64913.1 6 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" PCG73934.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG79642.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG64138.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" PCG68677.1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" PCG64114.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG69536.1 17 Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-176408 "APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase" PCG67032.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" PCG76832.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-156711 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Polo-like kinase mediated events" PCG74476.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG65732.1 31 MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-5973;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-6113;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-5994;MetaCyc: PWY-6519;MetaCyc: PWY-8049 "Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis" PCG71276.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG71880.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG71455.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG76287.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG67804.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG71056.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG75214.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" PCG62684.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG72843.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" PCG75421.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG67698.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" PCG66948.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" PCG73576.1 14 MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)" PCG77921.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" PCG63572.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG78498.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG65292.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" PCG72741.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG80600.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG75066.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG79035.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG63970.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" PCG77387.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG75232.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG63148.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG64103.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG79517.1 8 MetaCyc: PWY-4983;MetaCyc: PWY-5154;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;MetaCyc: PWY-5;Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5 "Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Arginine biosynthesis";"Urea cycle";"Canavanine biosynthesis";"Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism" PCG80612.1 5 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-3341 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)" PCG63674.1 14 MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7725;MetaCyc: PWY-7724 "Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" PCG76698.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination" PCG70190.1 19 Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8964046 "Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL assembly";"LDL remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"VLDL clearance" PCG73631.1 179 Reactome: R-HSA-4608870;Reactome: R-HSA-9636383;Reactome: R-HSA-69481;Reactome: R-HSA-4641263;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-975956;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-936964;Reactome: R-HSA-917937;Reactome: R-HSA-2122948;Reactome: R-HSA-937042;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5685942;Reactome: R-HSA-6781823;Reactome: R-HSA-5689896;Reactome: R-HSA-8849469;Reactome: R-HSA-1169408;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-2122947;Reactome: R-HSA-532668;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-9613829;Reactome: R-HSA-2871837;Reactome: R-HSA-8875360;Reactome: R-HSA-2173791;Reactome: R-HSA-5693607;Reactome: R-HSA-1236382;Reactome: R-HSA-68949;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-110320;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-3322077;Reactome: R-HSA-5632684;Reactome: R-HSA-5654727;Reactome: R-HSA-2559580;Reactome: R-HSA-1253288;Reactome: R-HSA-450321;Reactome: R-HSA-205043;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-72764;Reactome: R-HSA-68827;Reactome: R-HSA-2691232;Reactome: R-HSA-9014325;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-975163;Reactome: R-HSA-5689901;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5689877;Reactome: R-HSA-2672351;Reactome: R-HSA-8866654;Reactome: R-HSA-209560;Reactome: R-HSA-3769402;Reactome: R-HSA-6781827;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-168638;Reactome: R-HSA-174490;Reactome: R-HSA-5654732;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-1295596;Reactome: R-HSA-9013507;Reactome: R-HSA-156902;Reactome: R-HSA-162588;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-2565942;Reactome: R-HSA-450408;Reactome: R-HSA-6804760;Reactome: R-HSA-3134975;Reactome: R-HSA-6783310;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-2979096;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-912631;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-2173795;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948747;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-192823;Reactome: R-HSA-8863795;Reactome: R-HSA-5656169;Reactome: R-HSA-5357905;Reactome: R-HSA-6791226;Reactome: R-HSA-5656121;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-975144;Reactome: R-HSA-174048;Reactome: R-HSA-69541;Reactome: R-HSA-182971;Reactome: R-HSA-977225;Reactome: R-HSA-168927;Reactome: R-HSA-5696394;Reactome: R-HSA-2467813;Reactome: R-HSA-6804756;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-8876493;Reactome: R-HSA-2173796;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-937041;Reactome: R-HSA-1358803;Reactome: R-HSA-2173788;Reactome: R-HSA-3785653;Reactome: R-HSA-983168;Reactome: R-HSA-9013973;Reactome: R-HSA-5696397;Reactome: R-HSA-175474;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-901032;Reactome: R-HSA-72689;Reactome: R-HSA-5357956;Reactome: R-HSA-936440;Reactome: R-HSA-201681;Reactome: R-HSA-174154;Reactome: R-HSA-209543;Reactome: R-HSA-445989;Reactome: R-HSA-174113;Reactome: R-HSA-72706;Reactome: R-HSA-2559585;Reactome: R-HSA-5655862;Reactome: R-HSA-6804757;Reactome: R-HSA-937072;Reactome: R-HSA-8866652;Reactome: R-HSA-5693565;Reactome: R-HSA-8852276;Reactome: R-HSA-5675221;Reactome: R-HSA-2559582;Reactome: R-HSA-110312;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-2408557;Reactome: R-HSA-110314;Reactome: R-HSA-69231;Reactome: R-HSA-6807004;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-5696395;Reactome: R-HSA-5654733;Reactome: R-HSA-9615710;Reactome: R-HSA-8951664;Reactome: R-HSA-1799339;Reactome: R-HSA-9637628;Reactome: R-HSA-6782135;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-156827;Reactome: R-HSA-9033241;Reactome: R-HSA-975957 "Asymmetric localization of PCP proteins";"Prevention of phagosomal-lysosomal fusion";"G2/M Checkpoints";"Regulation of FZD by ubiquitination";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Iron uptake and transport";"Activated NOTCH1 Transmits Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"HDR through Homologous Recombination (HRR)";"Formation of TC-NER Pre-Incision Complex";"Ovarian tumor domain proteases";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"ISG15 antiviral mechanism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Chaperone Mediated Autophagy";"FCERI mediated NF-kB activation";"InlB-mediated entry of Listeria monocytogenes into host cell";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Processing of DNA double-strand break ends";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Orc1 removal from chromatin";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Translesion Synthesis by POLH";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Glycogen synthesis";"Hedgehog 'on' state";"Negative regulation of FGFR2 signaling";"Oxidative Stress Induced Senescence";"Downregulation of ERBB4 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NRIF signals cell death from the nucleus";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Eukaryotic Translation Termination";"CDT1 association with the CDC6:ORC:origin complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"Degradation of AXIN";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Metalloprotease DUBs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Josephin domain DUBs";"Stimuli-sensing channels";"E3 ubiquitin ligases ubiquitinate target proteins";"NF-kB is activated and signals survival";"Deactivation of the beta-catenin transactivating complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NOD1/2 Signaling Pathway";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR3 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Spry regulation of FGF signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Peptide chain elongation";"Budding and maturation of HIV virion";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of PLK1 Activity at G2/M Transition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of TP53 Activity through Methylation";"Regulation of innate immune responses to cytosolic DNA";"Fanconi Anemia Pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of signaling by CBL";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN localization";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"Viral mRNA Translation";"Downregulation of ERBB2 signaling";"Termination of translesion DNA synthesis";"Regulation of TNFR1 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translesion synthesis by POLI";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Stabilization of p53";"EGFR downregulation";"Amyloid fiber formation";"TICAM1, RIP1-mediated IKK complex recruitment";"DNA Damage Recognition in GG-NER";"Separation of Sister Chromatids";"Regulation of TP53 Activity through Phosphorylation";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"InlA-mediated entry of Listeria monocytogenes into host cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"IKK complex recruitment mediated by RIP1";"Downregulation of ERBB2:ERBB3 signaling";"Downregulation of TGF-beta receptor signaling";"Myoclonic epilepsy of Lafora";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1-dependent activation of IRF3/IRF7";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Assembly Of The HIV Virion";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"ER Quality Control Compartment (ERQC)";"Formation of a pool of free 40S subunits";"TNFR1-induced NFkappaB signaling pathway";"Negative regulators of DDX58/IFIH1 signaling";"TCF dependent signaling in response to WNT";"APC/C:Cdc20 mediated degradation of Securin";"p75NTR recruits signalling complexes";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"SCF-beta-TrCP mediated degradation of Emi1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Oncogene Induced Senescence";"Translesion synthesis by POLK";"Regulation of TP53 Degradation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of MAPK pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Translesion synthesis by REV1";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Selenocysteine synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Cyclin D associated events in G1";"Negative regulation of MET activity";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Formation of Incision Complex in GG-NER";"Negative regulation of FGFR4 signaling";"Late endosomal microautophagy";"Neddylation";"SRP-dependent cotranslational protein targeting to membrane";"Modulation by Mtb of host immune system";"Dual incision in TC-NER";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peroxisomal protein import";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG68835.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG71531.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG79712.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG69443.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" PCG78756.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG66450.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" PCG78811.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" PCG80835.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG70949.1 3 Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695 "Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation" PCG70946.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" PCG78592.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG75128.1 56 Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733 "ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation" PCG68135.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" PCG70787.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG80048.1 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG75057.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" PCG77218.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" PCG67283.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" PCG79098.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" PCG71420.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" PCG68081.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-202433 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules" PCG74297.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG75235.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" PCG67501.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG76360.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080 "Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)" PCG74625.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" PCG73817.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG70546.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-209560;Reactome: R-HSA-209543;Reactome: R-HSA-5205685 "Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy" PCG71063.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG80018.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG62828.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG73246.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" PCG78387.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" PCG68459.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG66048.1 9 MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6147;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-6983 "Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis" PCG62493.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" PCG69310.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" PCG63900.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG74236.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" PCG79260.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" PCG75375.1 7 Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2 "Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism" PCG68383.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG79919.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" PCG68238.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG70766.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG73387.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG74441.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" PCG63647.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" PCG73961.1 13 Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-4086398 "PLC beta mediated events";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway" PCG68889.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" PCG79621.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG69645.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG74467.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG69970.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" PCG73510.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" PCG74657.1 5 KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)" PCG69646.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" PCG71530.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG80418.1 7 KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-7625;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11 "Inositol phosphate metabolism";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Phosphatidylinositol signaling system" PCG74328.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" PCG80163.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG75604.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG78026.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG76599.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" PCG73913.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG66244.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG75956.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex" PCG80268.1 14 Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Macroautophagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids" PCG72742.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" PCG68166.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG68909.1 13 KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52 "Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" PCG66713.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG78134.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG69684.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG75400.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG66251.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG78704.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" PCG78591.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG80628.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG62959.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" PCG64428.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG71469.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" PCG64164.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG74988.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG71841.1 52 Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-76061;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-167243;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-113418 "HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex" PCG67616.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG66387.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" PCG68046.1 58 Reactome: R-HSA-5689901;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837 "Metalloprotease DUBs";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Neddylation";"FCERI mediated NF-kB activation" PCG78538.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG69866.1 11 KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-6596;MetaCyc: PWY-7185;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-5695;KEGG: 00230+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7821 "Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Inosine 5'-phosphate degradation";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Tunicamycin biosynthesis" PCG79163.1 7 Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" PCG78354.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG64423.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" PCG63452.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" PCG72398.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" PCG67746.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" PCG74765.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" PCG71145.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" PCG78174.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" PCG77185.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG77789.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG64770.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" PCG63472.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG68823.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG73279.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG77386.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG76902.1 3 KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" PCG68206.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG79220.1 5 MetaCyc: PWY-7782;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500;Reactome: R-HSA-75896 "Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis" PCG63300.1 10 KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Galactose metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series" PCG75469.1 31 KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-6113;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5973;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7664 "Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Superpathway of mycolate biosynthesis";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Cis-vaccenate biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)" PCG75239.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG78641.1 33 Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159230 "Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA" PCG73239.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification" PCG79666.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" PCG72977.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" PCG67730.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" PCG75814.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG76093.1 12 Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-6978;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5873;MetaCyc: PWY-5856;Reactome: R-HSA-1268020 "Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Mitochondrial protein import" PCG69870.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation" PCG76794.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" PCG79871.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" PCG64132.1 11 Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-400253;Reactome: R-HSA-212436;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2426168 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"Circadian Clock";"Generic Transcription Pathway";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)" PCG75948.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" PCG64201.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-9020702 "Neutrophil degranulation";"Interleukin-1 signaling" PCG67887.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" PCG73632.1 179 Reactome: R-HSA-6804760;Reactome: R-HSA-6783310;Reactome: R-HSA-3134975;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-2565942;Reactome: R-HSA-450408;Reactome: R-HSA-1295596;Reactome: R-HSA-9013507;Reactome: R-HSA-156902;Reactome: R-HSA-5696400;Reactome: R-HSA-162588;Reactome: R-HSA-8856825;Reactome: R-HSA-174490;Reactome: R-HSA-5654732;Reactome: R-HSA-5684264;Reactome: R-HSA-195253;Reactome: R-HSA-5689877;Reactome: R-HSA-2672351;Reactome: R-HSA-8866654;Reactome: R-HSA-209560;Reactome: R-HSA-3769402;Reactome: R-HSA-6781827;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-1236974;Reactome: R-HSA-5205685;Reactome: R-HSA-4641257;Reactome: R-HSA-975163;Reactome: R-HSA-5689901;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-72764;Reactome: R-HSA-68827;Reactome: R-HSA-2691232;Reactome: R-HSA-450321;Reactome: R-HSA-205043;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-3322077;Reactome: R-HSA-5654727;Reactome: R-HSA-2559580;Reactome: R-HSA-1253288;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-110320;Reactome: R-HSA-5610783;Reactome: R-HSA-8941858;Reactome: R-HSA-9613829;Reactome: R-HSA-8875360;Reactome: R-HSA-2871837;Reactome: R-HSA-5693607;Reactome: R-HSA-2173791;Reactome: R-HSA-1236382;Reactome: R-HSA-68949;Reactome: R-HSA-5689896;Reactome: R-HSA-5685942;Reactome: R-HSA-6781823;Reactome: R-HSA-8849469;Reactome: R-HSA-1169408;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-2122947;Reactome: R-HSA-532668;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-2894862;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-937042;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-2122948;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-917937;Reactome: R-HSA-936964;Reactome: R-HSA-4608870;Reactome: R-HSA-9636383;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-4641263;Reactome: R-HSA-975956;Reactome: R-HSA-5675482;Reactome: R-HSA-156827;Reactome: R-HSA-9033241;Reactome: R-HSA-975957;Reactome: R-HSA-9637628;Reactome: R-HSA-5668541;Reactome: R-HSA-6782135;Reactome: R-HSA-917729;Reactome: R-HSA-5654733;Reactome: R-HSA-5696395;Reactome: R-HSA-9615710;Reactome: R-HSA-8951664;Reactome: R-HSA-1799339;Reactome: R-HSA-6807004;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-8856828;Reactome: R-HSA-2559582;Reactome: R-HSA-110312;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-2408557;Reactome: R-HSA-110314;Reactome: R-HSA-69231;Reactome: R-HSA-8852276;Reactome: R-HSA-5675221;Reactome: R-HSA-209543;Reactome: R-HSA-445989;Reactome: R-HSA-174113;Reactome: R-HSA-72706;Reactome: R-HSA-2559585;Reactome: R-HSA-6804757;Reactome: R-HSA-5655862;Reactome: R-HSA-8866652;Reactome: R-HSA-937072;Reactome: R-HSA-5693565;Reactome: R-HSA-201681;Reactome: R-HSA-174154;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-901032;Reactome: R-HSA-72689;Reactome: R-HSA-5357956;Reactome: R-HSA-936440;Reactome: R-HSA-937041;Reactome: R-HSA-1358803;Reactome: R-HSA-3785653;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-9013973;Reactome: R-HSA-5696397;Reactome: R-HSA-175474;Reactome: R-HSA-8876493;Reactome: R-HSA-2173796;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-6804756;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-975144;Reactome: R-HSA-69541;Reactome: R-HSA-174048;Reactome: R-HSA-182971;Reactome: R-HSA-977225;Reactome: R-HSA-168927;Reactome: R-HSA-5696394;Reactome: R-HSA-2467813;Reactome: R-HSA-5656169;Reactome: R-HSA-6791226;Reactome: R-HSA-5357905;Reactome: R-HSA-5656121;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948747;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-192823;Reactome: R-HSA-8863795;Reactome: R-HSA-2979096;Reactome: R-HSA-6782210;Reactome: R-HSA-8939236;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-912631;Reactome: R-HSA-2173795;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590 "Regulation of TP53 Activity through Methylation";"Fanconi Anemia Pathway";"Regulation of innate immune responses to cytosolic DNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of PLK1 Activity at G2/M Transition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Spry regulation of FGF signaling";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Peptide chain elongation";"Dual Incision in GG-NER";"Budding and maturation of HIV virion";"Cargo recognition for clathrin-mediated endocytosis";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR3 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Degradation of beta-catenin by the destruction complex";"Josephin domain DUBs";"Stimuli-sensing channels";"E3 ubiquitin ligases ubiquitinate target proteins";"NF-kB is activated and signals survival";"Deactivation of the beta-catenin transactivating complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"ER-Phagosome pathway";"Pink/Parkin Mediated Mitophagy";"Degradation of AXIN";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Metalloprotease DUBs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Eukaryotic Translation Termination";"CDT1 association with the CDC6:ORC:origin complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NRIF signals cell death from the nucleus";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Glycogen synthesis";"Negative regulation of FGFR2 signaling";"Oxidative Stress Induced Senescence";"Downregulation of ERBB4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Translesion Synthesis by POLH";"Degradation of GLI2 by the proteasome";"Regulation of RUNX3 expression and activity";"Chaperone Mediated Autophagy";"InlB-mediated entry of Listeria monocytogenes into host cell";"FCERI mediated NF-kB activation";"Processing of DNA double-strand break ends";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Orc1 removal from chromatin";"Ovarian tumor domain proteases";"HDR through Homologous Recombination (HRR)";"Formation of TC-NER Pre-Incision Complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"ISG15 antiviral mechanism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"IRAK2 mediated activation of TAK1 complex";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Activated NOTCH1 Transmits Signal to the Nucleus";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"Iron uptake and transport";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Asymmetric localization of PCP proteins";"Prevention of phagosomal-lysosomal fusion";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of necroptotic cell death";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peroxisomal protein import";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Modulation by Mtb of host immune system";"TNFR2 non-canonical NF-kB pathway";"Dual incision in TC-NER";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of FGFR4 signaling";"Formation of Incision Complex in GG-NER";"Late endosomal microautophagy";"Neddylation";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of MET activity";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Clathrin-mediated endocytosis";"Senescence-Associated Secretory Phenotype (SASP)";"Translesion synthesis by REV1";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Selenocysteine synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Cyclin D associated events in G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of MAPK pathway";"p75NTR recruits signalling complexes";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"SCF-beta-TrCP mediated degradation of Emi1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Oncogene Induced Senescence";"Regulation of TP53 Degradation";"Translesion synthesis by POLK";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TCF dependent signaling in response to WNT";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"ER Quality Control Compartment (ERQC)";"Formation of a pool of free 40S subunits";"TNFR1-induced NFkappaB signaling pathway";"Negative regulators of DDX58/IFIH1 signaling";"IKK complex recruitment mediated by RIP1";"Downregulation of ERBB2:ERBB3 signaling";"Myoclonic epilepsy of Lafora";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1-dependent activation of IRF3/IRF7";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Assembly Of The HIV Virion";"InlA-mediated entry of Listeria monocytogenes into host cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Regulation of TP53 Activity through Phosphorylation";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Stabilization of p53";"APC/C:Cdc20 mediated degradation of Cyclin B";"EGFR downregulation";"Amyloid fiber formation";"TICAM1, RIP1-mediated IKK complex recruitment";"DNA Damage Recognition in GG-NER";"Separation of Sister Chromatids";"Termination of translesion DNA synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of TNFR1 signaling";"Translesion synthesis by POLI";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN localization";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"Viral mRNA Translation";"Downregulation of ERBB2 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Regulation of signaling by CBL";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling" PCG65041.1 57 Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577 "CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Degradation of DVL";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Neddylation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21" PCG71081.1 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism" PCG80101.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG69109.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" PCG80549.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG77872.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG63952.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-9610379 "Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events" PCG69749.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" PCG76435.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" PCG74706.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG67469.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" PCG70606.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" PCG68229.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" PCG78525.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG74274.1 34 Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-69656;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-69202;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-69273;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-69231 "Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Cyclin E associated events during G1/S transition";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin D associated events in G1" PCG73623.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG69851.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" PCG80846.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG70442.1 13 MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-6383 "(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" PCG67080.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" PCG79013.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" PCG80879.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" PCG73107.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" PCG78596.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG67196.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG72119.1 19 Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041 "Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"VLDL clearance";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"VLDL assembly";"LDL remodeling" PCG67175.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG68795.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" PCG65178.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" PCG68231.1 1 Reactome: R-HSA-8856825 "Cargo recognition for clathrin-mediated endocytosis" PCG66792.1 57 Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs" PCG68287.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" PCG81099.1 3 MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol" PCG75366.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597 "Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (z) signalling events" PCG80107.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" PCG77139.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade" PCG77614.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG66678.1 7 MetaCyc: PWY-5188;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" PCG79619.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG75695.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG74762.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" PCG76912.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" PCG79927.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG79320.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" PCG70644.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG68767.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG72814.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" PCG73738.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" PCG74001.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion" PCG79326.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" PCG63226.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Photosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ATP biosynthesis";"Oxidative phosphorylation" PCG66424.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" PCG77969.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG72791.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" PCG77596.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" PCG76888.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG77285.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" PCG70073.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG66767.1 5 Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214 "TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins" PCG64709.1 6 Reactome: R-HSA-9022692;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9022537 "Regulation of MECP2 expression and activity";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex" PCG72200.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG79241.1 13 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206308;KEGG: 00604+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Galactose metabolism";"MPS IV - Morquio syndrome B";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Keratan sulfate degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"HS-GAG degradation";"Other glycan degradation";"Glycosaminoglycan degradation" PCG74218.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG72357.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG66614.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG63312.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-450408 "Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA" PCG76161.1 10 MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6535;MetaCyc: PWY-6536;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;Reactome: R-HSA-916853;KEGG: 00410+2.6.1.19;KEGG: 00650+2.6.1.19 "4-aminobutanoate degradation V";"Propanoate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation I";"4-aminobutanoate degradation III";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"Degradation of GABA";"beta-Alanine metabolism";"Butanoate metabolism" PCG72743.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" PCG74209.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG70623.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" PCG70424.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" PCG66615.1 1 Reactome: R-HSA-70171 "Glycolysis" PCG74542.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" PCG80380.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" PCG70675.1 1 Reactome: R-HSA-3295583 "TRP channels" PCG75038.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG68045.1 58 Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017 "MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Metalloprotease DUBs";"Downstream TCR signaling";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6" PCG71512.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG74269.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG65126.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG78967.1 31 MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-5973;MetaCyc: PWY-5367;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-5147;MetaCyc: PWY-6113;MetaCyc: PWY-5366;MetaCyc: PWY-7858;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41 "Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Gondoate biosynthesis (anaerobic)";"";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Cis-vaccenate biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism" PCG76972.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG73951.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG78386.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG80489.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG63948.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG75839.1 17 Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5696400 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER" PCG77987.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" PCG73889.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" PCG77498.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214841;Reactome: R-HSA-2299718 "Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes" PCG75661.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG65179.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG72189.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" PCG70870.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" PCG76240.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" PCG63932.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG80604.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG81028.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Repression of WNT target genes" PCG67391.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG67152.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG79262.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG63223.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" PCG69915.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG69649.1 8 Reactome: R-HSA-74217;MetaCyc: PWY-6609;Reactome: R-HSA-6798695;MetaCyc: PWY-7179;Reactome: R-HSA-5683826;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611 "Purine salvage";"Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V" PCG76921.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2 "Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism" PCG76282.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" PCG74737.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" PCG76795.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" PCG63039.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-8939243;Reactome: R-HSA-2559580 "Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence" PCG71423.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" PCG66380.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" PCG67755.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG76860.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG64880.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" PCG80446.1 14 MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II" PCG77557.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" PCG67195.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG68678.1 10 MetaCyc: PWY-7921;MetaCyc: PWY-7661;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4717374;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.83 "Protein O-mannosylation I (yeast)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"O-linked glycosylation of mucins";"N-Glycan biosynthesis" PCG79673.1 5 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;Reactome: R-HSA-901032;MetaCyc: PWY-7511 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Protein ubiquitination" PCG66650.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" PCG71422.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" PCG77104.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" PCG63863.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG76935.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG77365.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA" PCG69690.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG68601.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4551638 "HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins" PCG67416.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" PCG75822.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" PCG80626.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" PCG67246.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG76222.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG65017.1 20 MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-735;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Propanoyl-coa degradation II" PCG73337.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946 "Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants" PCG66465.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" PCG71044.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG79371.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" PCG69528.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" PCG68894.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG78073.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG78419.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG74583.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG70599.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription" PCG74448.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-5653 "Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" PCG63726.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" PCG80127.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" PCG80834.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG79014.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" PCG73042.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG68902.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG73372.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" PCG71768.1 10 Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-163680;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-9619483 "Macroautophagy";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"AMPK inhibits chREBP transcriptional activation activity";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs" PCG69760.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" PCG74547.1 11 KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-7124;MetaCyc: PWY-6728;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-7268;MetaCyc: PWY-6549;KEGG: 00720+1.1.1.42;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969 "Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"L-glutamine biosynthesis III";"Carbon fixation pathways in prokaryotes";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" PCG75525.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG67846.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG80711.1 14 KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-5981;MetaCyc: PWY-7587 "Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)" PCG65426.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" PCG78848.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" PCG75253.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" PCG75305.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" PCG74455.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" PCG78111.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG74763.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" PCG63937.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG74564.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG76649.1 56 Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128 "CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling" PCG70659.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" PCG74398.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" PCG73505.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG77061.1 14 Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis" PCG65952.1 6 MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" PCG74595.1 3 Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105 "Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation" PCG79651.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG70121.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" PCG76489.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG63904.1 12 Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4 "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Monobactam biosynthesis";"Sulfur metabolism";"Purine metabolism";"Selenate reduction";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Selenocompound metabolism" PCG77324.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG78701.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" PCG79407.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG67679.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG72036.1 2 Reactome: R-HSA-1299308;Reactome: R-HSA-5576886 "Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)";"Phase 4 - resting membrane potential" PCG78710.1 7 MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" PCG65487.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" PCG64000.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG79048.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" PCG80073.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" PCG80701.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" PCG69118.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase" PCG80390.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG75121.1 4 MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" PCG79174.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG73189.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" PCG62599.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG74379.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" PCG69101.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" PCG71765.1 11 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571 "Human papillomavirus infection";"Thermogenesis";"E3 ubiquitin ligases ubiquitinate target proteins";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Cytosolic sensors of pathogen-associated DNA";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)" PCG79516.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG74586.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG63597.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" PCG81059.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" PCG73587.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" PCG67198.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" PCG76887.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG74426.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG72154.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG65835.1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110329 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" PCG73918.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" PCG69264.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" PCG73619.1 33 Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Separation of Sister Chromatids";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus" PCG63133.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" PCG79850.1 14 MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-75109 "2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Anandamide biosynthesis I";"Synthesis of PE";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Triglyceride biosynthesis" PCG63646.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" PCG76488.1 24 Reactome: R-HSA-5625740;KEGG: 04150+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-389357;Reactome: R-HSA-202424;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-5607764;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "RHO GTPases activate PKNs";"mTOR signaling pathway";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"CD28 dependent PI3K/Akt signaling";"Downstream TCR signaling";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"RSK activation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"Human papillomavirus infection";"Integrin signaling";"CLEC7A (Dectin-1) signaling";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG75163.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway" PCG73331.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" PCG73430.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG70621.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG69115.1 18 MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1 "Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis" PCG64254.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG77042.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG64335.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG78607.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" PCG68279.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG68295.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG68747.1 6 Reactome: R-HSA-6811440;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005 "Retrograde transport at the Trans-Golgi-Network";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport" PCG70056.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" PCG72462.1 4 Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463;Reactome: R-HSA-196741 "Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism" PCG80340.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG63722.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" PCG78682.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG74390.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG80169.1 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" PCG64835.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG76507.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" PCG71861.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG75083.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" PCG75774.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG63814.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" PCG71459.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" PCG74944.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" PCG69124.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" PCG68504.1 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" PCG79327.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" PCG77380.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" PCG72305.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" PCG78179.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" PCG74804.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" PCG63066.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" PCG67940.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-5620912 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Anchoring of the basal body to the plasma membrane" PCG80238.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" PCG80342.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" PCG65222.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG74911.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" PCG63885.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" PCG66046.1 9 MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-6983 "Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis" PCG69688.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG63501.1 1 Reactome: R-HSA-264876 "Insulin processing" PCG71490.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG67100.1 3 Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" PCG66480.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" PCG73609.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG78703.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" PCG64059.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-936440 "Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling" PCG67109.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG66226.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" PCG69425.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" PCG71111.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" PCG77729.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" PCG77808.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" PCG77138.1 5 Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" PCG64139.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" PCG69810.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" PCG77227.1 15 Reactome: R-HSA-6811558;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-1433557;Reactome: R-HSA-912631;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-388841;Reactome: R-HSA-9009391;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"Signaling by SCF-KIT";"Regulation of signaling by CBL";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Costimulation by the CD28 family";"Extra-nuclear estrogen signaling";"Interleukin-7 signaling";"RET signaling" PCG68302.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG64867.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG78658.1 13 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-5687128;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"EPHB-mediated forward signaling";"Human papillomavirus infection";"NRAGE signals death through JNK";"Rho GTPase cycle";"Relaxin signaling pathway";"G alpha (q) signalling events";"MAPK6/MAPK4 signaling";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events" PCG69085.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" PCG76983.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857 "Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Keratan sulfate degradation" PCG74897.1 17 Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-2559580;Reactome: R-HSA-111448;Reactome: R-HSA-1912408;Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-9616222;Reactome: R-HSA-69656;Reactome: R-HSA-113501;Reactome: R-HSA-1538133;Reactome: R-HSA-139915;Reactome: R-HSA-8953750 "G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"Oxidative Stress Induced Senescence";"Activation of NOXA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcriptional regulation of granulopoiesis";"Cyclin A:Cdk2-associated events at S phase entry";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G0 and Early G1";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6" PCG79757.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" PCG71477.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" PCG75981.1 5 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" PCG65457.1 4 Reactome: R-HSA-189483;MetaCyc: PWY-6972;Reactome: R-HSA-5679001;Reactome: R-HSA-382556 "Heme degradation";"Oleandomycin activation/inactivation";"Defective ABCC2 causes Dubin-Johnson syndrome";"ABC-family proteins mediated transport" PCG68425.1 7 Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-1221632 "Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic synapsis" PCG63782.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" PCG77097.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Activation of RAC1";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG74451.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG79293.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" PCG67774.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424 "FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling" PCG69643.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" PCG66489.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" PCG62682.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG72226.1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005 "Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport" PCG78923.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG68029.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" PCG70365.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG79325.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" PCG75980.1 30 Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6782210 "TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER" PCG68332.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG71688.1 18 MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7227;MetaCyc: PWY-7197 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation" PCG66452.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" PCG77377.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG81045.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG79261.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape" PCG69691.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" PCG65597.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG63665.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" PCG75011.1 16 Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-9018519 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression" PCG68101.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG62600.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG63138.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG66491.1 4 Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75 "tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis" PCG67505.1 6 MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709 "Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins" PCG75944.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128 "Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling" PCG65793.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG63237.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG62817.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG72654.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG77273.1 9 Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Neutrophil degranulation" PCG76779.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG67722.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" PCG78392.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" PCG77506.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG69911.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" PCG72589.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" PCG64300.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" PCG68660.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG79532.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" PCG77766.1 5 MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" PCG65107.1 5 Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC" PCG71818.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" PCG74514.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4551638 "HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins" PCG66552.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" PCG78787.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" PCG76194.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG65316.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG77662.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" PCG74206.1 17 MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6679;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Propanoate metabolism";"Carnitine metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Biotin transport and metabolism";"Jadomycin biosynthesis";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"3-hydroxypropanoate cycle";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)" PCG71230.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG65140.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-8853884 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX" PCG68392.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG63241.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" PCG79469.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" PCG74447.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" PCG75118.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" PCG76918.1 4 KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" PCG63506.1 1 MetaCyc: PWY-7379 "Mrna capping II" PCG75807.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG68406.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG66181.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" PCG67697.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" PCG78455.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG67752.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG64089.1 5 Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00630+4.2.1.3 "Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism" PCG71208.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" PCG75422.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" PCG74989.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG68064.1 15 Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939 "HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)" PCG80906.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" PCG79187.1 1 Reactome: R-HSA-1296061 "HCN channels" PCG76494.1 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases" PCG64882.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" PCG76808.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" PCG66631.1 5 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Neutrophil degranulation" PCG62744.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" PCG72868.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation" PCG69100.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG77100.1 5 MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16 "UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" PCG78167.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" PCG80272.1 14 Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-5620924;Reactome: R-HSA-1632852;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Macroautophagy";"COPI-mediated anterograde transport";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" PCG66502.1 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" PCG64160.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" PCG62444.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG70364.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG65584.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" PCG69824.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" PCG64942.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG65164.1 8 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway" PCG65533.1 9 MetaCyc: PWY-6549;MetaCyc: PWY-6963;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964 "L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II" PCG78501.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG72637.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" PCG63411.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" PCG77205.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG80677.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis" PCG79814.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG80132.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" PCG72353.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG72051.1 24 Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-9009391 "Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling" PCG72597.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" PCG67242.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" PCG81066.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" PCG62907.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" PCG65096.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920 "Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability" PCG76017.1 9 Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis" PCG66679.1 7 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-379716;Reactome: R-HSA-6782315 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"tRNA modification in the nucleus and cytosol" PCG75710.1 12 MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-801 "Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion" PCG65334.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6807505 "Protein ubiquitination";"RNA polymerase II transcribes snRNA genes" PCG78344.1 13 KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52 "Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" PCG71191.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis" PCG74431.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" PCG74212.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" PCG71271.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" PCG73268.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" PCG73412.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" PCG74616.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" PCG73336.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-445355 "Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction" PCG63739.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG70234.1 1 Reactome: R-HSA-211981 "Xenobiotics" PCG81071.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG69033.1 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300 "DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA" PCG67952.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" PCG76863.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" PCG78101.1 15 Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" PCG70951.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG67744.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" PCG70896.1 1 Reactome: R-HSA-400253 "Circadian Clock" PCG71073.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6807505 "Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes" PCG75570.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG72507.1 13 KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-7909;KEGG: 00720+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030 "One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"L-histidine degradation III" PCG68052.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" PCG75984.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG78926.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG69031.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" PCG79370.1 34 Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-9639288;Reactome: R-HSA-159227;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-159231 "NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"HCMV Early Events";"snRNP Assembly";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Amino acids regulate mTORC1";"Transport of the SLBP independent Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript" PCG75995.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51 "Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism" PCG79186.1 1 Reactome: R-HSA-1296061 "HCN channels" PCG68034.1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287 "RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery" PCG72872.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG77102.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" PCG78040.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859 "Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly" PCG67101.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" PCG74409.1 14 KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-4302;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254 "Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Respiratory electron transport";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"TCA cycle VII (acetate-producers)" PCG76695.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" PCG75429.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG78546.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499 "RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane" PCG67705.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" PCG79402.1 17 KEGG: 00230+2.4.2.1;MetaCyc: PWY-7179;Reactome: R-HSA-74259;MetaCyc: PWY-6627;KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;MetaCyc: PWY-6644;Reactome: R-HSA-74217;MetaCyc: PWY-6620;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6608 "Purine metabolism";"Purine deoxyribonucleosides degradation I";"Purine catabolism";"Salinosporamide A biosynthesis";"Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Fluoroacetate and fluorothreonine biosynthesis";"Purine salvage";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Guanosine nucleotides degradation III" PCG80710.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis" PCG71769.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" PCG68379.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG63387.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" PCG71409.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" PCG63083.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8964208 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Phenylalanine metabolism" PCG72598.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" PCG63296.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" PCG77483.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG77395.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG80522.1 4 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-383280 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Nuclear Receptor transcription pathway" PCG81017.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" PCG67415.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" PCG66356.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG76557.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG79596.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" PCG77865.1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" PCG76476.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG76814.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG64658.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" PCG80109.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Attenuation phase";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor" PCG65054.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142 "snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins" PCG72842.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" PCG63765.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG79816.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" PCG78625.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG64093.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG80999.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG74368.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" PCG74049.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" PCG78935.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" PCG67237.1 10 Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-611105 "Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport" PCG76203.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG66247.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG67231.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG65941.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" PCG63734.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG67002.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG72022.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG62578.1 15 Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167242 "Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat" PCG69194.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" PCG69815.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG76744.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG71844.1 1 Reactome: R-HSA-8963901 "Chylomicron remodeling" PCG76372.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" PCG73703.1 1 Reactome: R-HSA-1483255 "PI Metabolism" PCG79714.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG74407.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" PCG72135.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG74310.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" PCG69591.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG80425.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis" PCG67082.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG70923.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG74909.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" PCG64259.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress" PCG67030.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription" PCG67434.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" PCG67949.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" PCG78221.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG72478.1 4 KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;Reactome: R-HSA-1614558 "Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Degradation of cysteine and homocysteine" PCG63761.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG63103.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" PCG79929.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" PCG64634.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG65333.1 2 Reactome: R-HSA-6807505;MetaCyc: PWY-7511 "RNA polymerase II transcribes snRNA genes";"Protein ubiquitination" PCG69718.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation" PCG79984.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" PCG67956.1 1 Reactome: R-HSA-3295583 "TRP channels" PCG81119.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" PCG71186.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG65012.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-6837;MetaCyc: PWY-7007 "alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)" PCG65929.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" PCG78691.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG74591.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG80930.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" PCG71488.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" PCG76893.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG64493.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG78444.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG63242.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" PCG73504.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG65979.1 5 Reactome: R-HSA-3134975;Reactome: R-HSA-6798695;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619 "Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN" PCG70104.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" PCG68588.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" PCG73369.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" PCG70454.1 6 MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5789 "Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle" PCG80214.1 5 MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279 "Fe(II) oxidation";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)" PCG72290.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG64569.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG75458.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667 "Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I" PCG75374.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2 "TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate and glutamine metabolism";"Arginine biosynthesis" PCG69233.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG76162.1 10 KEGG: 00650+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;Reactome: R-HSA-916853;MetaCyc: PWY-5022;KEGG: 00640+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6535 "Butanoate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation III";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"Degradation of GABA";"4-aminobutanoate degradation V";"Propanoate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation I" PCG80346.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Formation of Incision Complex in GG-NER";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" PCG77913.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG70625.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" PCG66086.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG69167.1 9 MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-7385;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism" PCG63760.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG73594.1 20 Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616 "Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange" PCG66004.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" PCG76078.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG76368.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG65109.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG68335.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG67926.1 11 MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7254;MetaCyc: PWY-7268;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7124;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)" PCG63491.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG64931.1 10 Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756 "Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation" PCG73085.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG80551.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG63395.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG72895.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" PCG63229.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" PCG76164.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901 "Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs" PCG74590.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG63419.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" PCG69424.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579 "Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange" PCG69020.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" PCG70944.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" PCG66370.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG63145.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG77303.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG65574.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG62763.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5358749;Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-389513;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-2500257 "Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"S37 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"CTLA4 inhibitory signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion" PCG68569.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" PCG63958.1 8 MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;MetaCyc: PWY-6174 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)" PCG78637.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG78059.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG79875.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" PCG79282.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG66348.1 4 Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-381033 "CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones" PCG68668.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" PCG69173.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" PCG80550.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG67845.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG75663.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG63544.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" PCG74273.1 34 Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-8939236;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-73762;Reactome: R-HSA-69273;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-69231;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827 "Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Cyclin D associated events in G1";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" PCG76170.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" PCG79047.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" PCG66135.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" PCG80674.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" PCG76521.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" PCG78199.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG64937.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG64301.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" PCG63526.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" PCG66911.1 4 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" PCG73872.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" PCG64885.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" PCG70641.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-901042;Reactome: R-HSA-983170 "ER-Phagosome pathway";"Calnexin/calreticulin cycle";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" PCG80685.1 17 Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801 "Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair" PCG80690.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" PCG67923.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" PCG79012.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" PCG71154.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG75530.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" PCG78114.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG75254.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2" PCG62803.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9609736;Reactome: R-HSA-3371571 "Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Long-term potentiation";"Signaling downstream of RAS mutants";"RAF activation";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Assembly and cell surface presentation of NMDA receptors";"HSF1-dependent transactivation" PCG78484.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436 "Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic" PCG69800.1 11 Reactome: R-HSA-428890;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-525793 "Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis" PCG66132.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" PCG73125.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG80490.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" PCG75212.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" PCG66422.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG75213.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" PCG74242.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" PCG66684.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG73299.1 10 Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167172 "Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome" PCG74480.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG80473.1 7 KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-6363 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation" PCG69981.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG64147.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG63288.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" PCG74541.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" PCG68330.1 15 Reactome: R-HSA-9665250;Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-5637810;Reactome: R-HSA-9634285;Reactome: R-HSA-8863795;Reactome: R-HSA-9665247;Reactome: R-HSA-1236382;Reactome: R-HSA-9665245;Reactome: R-HSA-9665251;Reactome: R-HSA-9665249;Reactome: R-HSA-9665244;Reactome: R-HSA-9664565 "Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Overexpressed ERBB2";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Signaling by ERBB2 KD Mutants" PCG75971.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" PCG69404.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" PCG71336.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" PCG78808.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8869496 "Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" PCG79256.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286 "tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" PCG76985.1 5 Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14 "Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation" PCG76053.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG80460.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" PCG73557.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" PCG64011.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" PCG78098.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" PCG72999.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" PCG72747.1 9 Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-380972 "Amino acids regulate mTORC1";"Neutrophil degranulation";"mTOR signalling";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK" PCG77977.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" PCG77768.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" PCG69731.1 15 KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-6142 "Purine metabolism";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" PCG69830.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" PCG68843.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" PCG68798.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG63625.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" PCG70102.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" PCG70830.1 11 MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;MetaCyc: PWY-882 "1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)" PCG74246.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" PCG63766.1 1 MetaCyc: PWY-7379 "Mrna capping II" PCG73999.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" PCG66879.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG74150.1 3 Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I" PCG76658.1 9 Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" PCG73119.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG79191.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG76677.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" PCG79625.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG73251.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" PCG80653.1 9 KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-196780;MetaCyc: PWY-6146;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263 "Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Biotin transport and metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Gluconeogenesis" PCG66874.1 8 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway" PCG68964.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604 "Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling" PCG73320.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" PCG70159.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG72840.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" PCG68551.1 7 Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-168333 "Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery" PCG77489.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG80892.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG69112.1 18 MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;MetaCyc: PWY-7383 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Anaerobic energy metabolism (invertebrates, cytosol)" PCG73289.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" PCG65928.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG64088.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" PCG67041.1 9 KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation" PCG72326.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG66377.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168325 "NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis" PCG62725.1 179 Reactome: R-HSA-72689;Reactome: R-HSA-901032;Reactome: R-HSA-936440;Reactome: R-HSA-5357956;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-5696397;Reactome: R-HSA-983168;Reactome: R-HSA-9013973;Reactome: R-HSA-175474;Reactome: R-HSA-937041;Reactome: R-HSA-1358803;Reactome: R-HSA-3785653;Reactome: R-HSA-2173788;Reactome: R-HSA-2173796;Reactome: R-HSA-8876493;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-5687128;Reactome: R-HSA-168927;Reactome: R-HSA-977225;Reactome: R-HSA-2467813;Reactome: R-HSA-5696394;Reactome: R-HSA-174048;Reactome: R-HSA-69541;Reactome: R-HSA-975144;Reactome: R-HSA-182971;Reactome: R-HSA-202424;Reactome: R-HSA-6791226;Reactome: R-HSA-5357905;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-174178;Reactome: R-HSA-192823;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-8863795;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-8948747;Reactome: R-HSA-9646399;Reactome: R-HSA-912631;Reactome: R-HSA-2173795;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-6782210;Reactome: R-HSA-2979096;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-5675482;Reactome: R-HSA-9033241;Reactome: R-HSA-5668541;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-8951664;Reactome: R-HSA-1799339;Reactome: R-HSA-5696395;Reactome: R-HSA-5654733;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9020702;Reactome: R-HSA-8856828;Reactome: R-HSA-937039;Reactome: R-HSA-6807004;Reactome: R-HSA-2408557;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-110314;Reactome: R-HSA-69231;Reactome: R-HSA-110312;Reactome: R-HSA-2559582;Reactome: R-HSA-5675221;Reactome: R-HSA-8852276;Reactome: R-HSA-6804757;Reactome: R-HSA-5655862;Reactome: R-HSA-2559585;Reactome: R-HSA-937072;Reactome: R-HSA-8866652;Reactome: R-HSA-5693565;Reactome: R-HSA-209543;Reactome: R-HSA-174113;Reactome: R-HSA-72706;Reactome: R-HSA-445989;Reactome: R-HSA-174154;Reactome: R-HSA-201681;Reactome: R-HSA-5632684;Reactome: R-HSA-3322077;Reactome: R-HSA-5654727;Reactome: R-HSA-1253288;Reactome: R-HSA-2559580;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-110320;Reactome: R-HSA-5610783;Reactome: R-HSA-5693607;Reactome: R-HSA-2173791;Reactome: R-HSA-68949;Reactome: R-HSA-1236382;Reactome: R-HSA-9613829;Reactome: R-HSA-2871837;Reactome: R-HSA-8875360;Reactome: R-HSA-532668;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1169408;Reactome: R-HSA-5685942;Reactome: R-HSA-6781823;Reactome: R-HSA-8849469;Reactome: R-HSA-5689896;Reactome: R-HSA-2122947;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-937042;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9010553;Reactome: R-HSA-936964;Reactome: R-HSA-917937;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-4641263;Reactome: R-HSA-975956;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9636383;Reactome: R-HSA-5607761;Reactome: R-HSA-6783310;Reactome: R-HSA-3134975;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-6804760;Reactome: R-HSA-450408;Reactome: R-HSA-2565942;Reactome: R-HSA-8856825;Reactome: R-HSA-162588;Reactome: R-HSA-5696400;Reactome: R-HSA-156902;Reactome: R-HSA-9013507;Reactome: R-HSA-1295596;Reactome: R-HSA-195253;Reactome: R-HSA-5654732;Reactome: R-HSA-174490;Reactome: R-HSA-5684264;Reactome: R-HSA-6781827;Reactome: R-HSA-3769402;Reactome: R-HSA-168638;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-2672351;Reactome: R-HSA-5689877;Reactome: R-HSA-209560;Reactome: R-HSA-8866654;Reactome: R-HSA-975163;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5689901;Reactome: R-HSA-1236974;Reactome: R-HSA-5205685;Reactome: R-HSA-9014325;Reactome: R-HSA-4641257;Reactome: R-HSA-2691232;Reactome: R-HSA-68827;Reactome: R-HSA-72764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-450321;Reactome: R-HSA-205043 "Formation of a pool of free 40S subunits";"ER Quality Control Compartment (ERQC)";"Negative regulators of DDX58/IFIH1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1-dependent activation of IRF3/IRF7";"Assembly Of The HIV Virion";"IKK complex recruitment mediated by RIP1";"Downregulation of ERBB2:ERBB3 signaling";"Myoclonic epilepsy of Lafora";"Downregulation of TGF-beta receptor signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"InlA-mediated entry of Listeria monocytogenes into host cells";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"MAPK6/MAPK4 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Amyloid fiber formation";"Separation of Sister Chromatids";"DNA Damage Recognition in GG-NER";"APC/C:Cdc20 mediated degradation of Cyclin B";"Stabilization of p53";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"EGFR downregulation";"Downstream TCR signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of TNFR1 signaling";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Viral mRNA Translation";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"Downregulation of ERBB2 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of PTEN localization";"Aggrephagy";"Regulation of signaling by CBL";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of necroptotic cell death";"Peroxisomal protein import";"TNFR2 non-canonical NF-kB pathway";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"Neddylation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of Incision Complex in GG-NER";"Negative regulation of FGFR4 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Interleukin-1 signaling";"Clathrin-mediated endocytosis";"IRAK1 recruits IKK complex";"Negative regulation of MET activity";"Selenocysteine synthesis";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Recognition of DNA damage by PCNA-containing replication complex";"Cyclin D associated events in G1";"Translesion synthesis by REV1";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of MAPK pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of TP53 Degradation";"Translesion synthesis by POLK";"Oncogene Induced Senescence";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"p75NTR recruits signalling complexes";"SCF-beta-TrCP mediated degradation of Emi1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"APC/C:Cdc20 mediated degradation of Securin";"TCF dependent signaling in response to WNT";"Hedgehog 'on' state";"Glycogen synthesis";"Negative regulation of FGFR2 signaling";"Downregulation of ERBB4 signaling";"Oxidative Stress Induced Senescence";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Translesion Synthesis by POLH";"Degradation of GLI2 by the proteasome";"Processing of DNA double-strand break ends";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Orc1 removal from chromatin";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Chaperone Mediated Autophagy";"FCERI mediated NF-kB activation";"InlB-mediated entry of Listeria monocytogenes into host cell";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"ISG15 antiviral mechanism";"HDR through Homologous Recombination (HRR)";"Formation of TC-NER Pre-Incision Complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ovarian tumor domain proteases";"NOTCH1 Intracellular Domain Regulates Transcription";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"IRAK2 mediated activation of TAK1 complex";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of expression of SLITs and ROBOs";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Iron uptake and transport";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Prevention of phagosomal-lysosomal fusion";"Dectin-1 mediated noncanonical NF-kB signaling";"Fanconi Anemia Pathway";"Regulation of innate immune responses to cytosolic DNA";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Regulation of TP53 Activity through Methylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PLK1 Activity at G2/M Transition";"Cargo recognition for clathrin-mediated endocytosis";"Budding and maturation of HIV virion";"Dual Incision in GG-NER";"Peptide chain elongation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Spry regulation of FGF signaling";"Degradation of beta-catenin by the destruction complex";"Negative regulation of FGFR3 signaling";"Membrane binding and targetting of GAG proteins";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Deactivation of the beta-catenin transactivating complex";"NOD1/2 Signaling Pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Stimuli-sensing channels";"Josephin domain DUBs";"NF-kB is activated and signals survival";"E3 ubiquitin ligases ubiquitinate target proteins";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Metalloprotease DUBs";"ER-Phagosome pathway";"Pink/Parkin Mediated Mitophagy";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Degradation of AXIN";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"CDT1 association with the CDC6:ORC:origin complex";"Eukaryotic Translation Termination";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NRIF signals cell death from the nucleus" PCG74205.1 17 MetaCyc: PWY-5966-1;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5743;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-3371599;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Pyruvate metabolism";"Carnitine metabolism";"Propanoate metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes" PCG77239.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" PCG76586.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" PCG63638.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" PCG76809.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" PCG72846.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" PCG65269.1 24 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239 "Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1" PCG68041.1 8 Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-9639288 "Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Amino acids regulate mTORC1" PCG79173.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG77173.1 9 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-113507 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" PCG68216.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" PCG72919.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG66919.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG81030.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265 "RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"Repression of WNT target genes" PCG68272.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662 "TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism" PCG65909.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG78809.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465 "Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins" PCG79086.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG68060.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826 "4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis" PCG71600.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG62718.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" PCG72856.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" PCG72317.1 6 Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110362 "Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair" PCG76286.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG79972.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG68740.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" PCG62727.1 179 Reactome: R-HSA-3769402;Reactome: R-HSA-6781827;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-168638;Reactome: R-HSA-2672351;Reactome: R-HSA-5689877;Reactome: R-HSA-8866654;Reactome: R-HSA-209560;Reactome: R-HSA-975163;Reactome: R-HSA-5689901;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-9014325;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-2691232;Reactome: R-HSA-72764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-450321;Reactome: R-HSA-205043;Reactome: R-HSA-6783310;Reactome: R-HSA-3134975;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-6804760;Reactome: R-HSA-450408;Reactome: R-HSA-2565942;Reactome: R-HSA-5696400;Reactome: R-HSA-162588;Reactome: R-HSA-8856825;Reactome: R-HSA-1295596;Reactome: R-HSA-156902;Reactome: R-HSA-9013507;Reactome: R-HSA-195253;Reactome: R-HSA-174490;Reactome: R-HSA-5654732;Reactome: R-HSA-5684264;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-937042;Reactome: R-HSA-2122948;Reactome: R-HSA-9010553;Reactome: R-HSA-917937;Reactome: R-HSA-936964;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-4641263;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-975956;Reactome: R-HSA-4608870;Reactome: R-HSA-9636383;Reactome: R-HSA-69481;Reactome: R-HSA-5654727;Reactome: R-HSA-3322077;Reactome: R-HSA-5632684;Reactome: R-HSA-2559580;Reactome: R-HSA-1253288;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-110320;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-2173791;Reactome: R-HSA-5693607;Reactome: R-HSA-68949;Reactome: R-HSA-1236382;Reactome: R-HSA-9613829;Reactome: R-HSA-8875360;Reactome: R-HSA-2871837;Reactome: R-HSA-532668;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-2894862;Reactome: R-HSA-5685942;Reactome: R-HSA-6781823;Reactome: R-HSA-5689896;Reactome: R-HSA-8849469;Reactome: R-HSA-1169408;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-2122947;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2408557;Reactome: R-HSA-69231;Reactome: R-HSA-110314;Reactome: R-HSA-2559582;Reactome: R-HSA-110312;Reactome: R-HSA-5675221;Reactome: R-HSA-8852276;Reactome: R-HSA-2559585;Reactome: R-HSA-5655862;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-937072;Reactome: R-HSA-5693565;Reactome: R-HSA-209543;Reactome: R-HSA-445989;Reactome: R-HSA-72706;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-201681;Reactome: R-HSA-975957;Reactome: R-HSA-5675482;Reactome: R-HSA-156827;Reactome: R-HSA-9033241;Reactome: R-HSA-5668541;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-8951664;Reactome: R-HSA-1799339;Reactome: R-HSA-917729;Reactome: R-HSA-5654733;Reactome: R-HSA-5696395;Reactome: R-HSA-9615710;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-977225;Reactome: R-HSA-168927;Reactome: R-HSA-5696394;Reactome: R-HSA-2467813;Reactome: R-HSA-975144;Reactome: R-HSA-69541;Reactome: R-HSA-174048;Reactome: R-HSA-182971;Reactome: R-HSA-202424;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-6791226;Reactome: R-HSA-5357905;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-192823;Reactome: R-HSA-8863795;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-8948747;Reactome: R-HSA-8939236;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-2173795;Reactome: R-HSA-912631;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-2979096;Reactome: R-HSA-6782210;Reactome: R-HSA-901032;Reactome: R-HSA-72689;Reactome: R-HSA-5357956;Reactome: R-HSA-936440;Reactome: R-HSA-168928;Reactome: R-HSA-5654726;Reactome: R-HSA-9013973;Reactome: R-HSA-983168;Reactome: R-HSA-5696397;Reactome: R-HSA-175474;Reactome: R-HSA-937041;Reactome: R-HSA-3785653;Reactome: R-HSA-1358803;Reactome: R-HSA-2173788;Reactome: R-HSA-8876493;Reactome: R-HSA-2173796;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-5687128 "Deactivation of the beta-catenin transactivating complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NOD1/2 Signaling Pathway";"Stimuli-sensing channels";"Josephin domain DUBs";"E3 ubiquitin ligases ubiquitinate target proteins";"NF-kB is activated and signals survival";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Metalloprotease DUBs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Eukaryotic Translation Termination";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NRIF signals cell death from the nucleus";"Fanconi Anemia Pathway";"Regulation of innate immune responses to cytosolic DNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Regulation of TP53 Activity through Methylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PLK1 Activity at G2/M Transition";"Dual Incision in GG-NER";"Budding and maturation of HIV virion";"Cargo recognition for clathrin-mediated endocytosis";"Spry regulation of FGF signaling";"Peptide chain elongation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of beta-catenin by the destruction complex";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR3 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"IRAK2 mediated activation of TAK1 complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of expression of SLITs and ROBOs";"Iron uptake and transport";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of FZD by ubiquitination";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Asymmetric localization of PCP proteins";"Prevention of phagosomal-lysosomal fusion";"G2/M Checkpoints";"Negative regulation of FGFR2 signaling";"Glycogen synthesis";"Hedgehog 'on' state";"Oxidative Stress Induced Senescence";"Downregulation of ERBB4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion Synthesis by POLH";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Processing of DNA double-strand break ends";"Orc1 removal from chromatin";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Chaperone Mediated Autophagy";"InlB-mediated entry of Listeria monocytogenes into host cell";"FCERI mediated NF-kB activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDR through Homologous Recombination (HRR)";"Formation of TC-NER Pre-Incision Complex";"Ovarian tumor domain proteases";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"ISG15 antiviral mechanism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Selenocysteine synthesis";"Cyclin D associated events in G1";"Recognition of DNA damage by PCNA-containing replication complex";"Senescence-Associated Secretory Phenotype (SASP)";"Translesion synthesis by REV1";"Negative regulation of MAPK pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oncogene Induced Senescence";"Translesion synthesis by POLK";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"p75NTR recruits signalling complexes";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"TCF dependent signaling in response to WNT";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of necroptotic cell death";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peroxisomal protein import";"TNFR2 non-canonical NF-kB pathway";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"Neddylation";"SRP-dependent cotranslational protein targeting to membrane";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of FGFR4 signaling";"Formation of Incision Complex in GG-NER";"Late endosomal microautophagy";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Amyloid fiber formation";"TICAM1, RIP1-mediated IKK complex recruitment";"DNA Damage Recognition in GG-NER";"Separation of Sister Chromatids";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Stabilization of p53";"APC/C:Cdc20 mediated degradation of Cyclin B";"EGFR downregulation";"Downstream TCR signaling";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of TNFR1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Viral mRNA Translation";"Downregulation of ERBB2 signaling";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of PTEN localization";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of signaling by CBL";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Gap-filling DNA repair synthesis and ligation in TC-NER";"ER Quality Control Compartment (ERQC)";"Formation of a pool of free 40S subunits";"TNFR1-induced NFkappaB signaling pathway";"Negative regulators of DDX58/IFIH1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Negative regulation of FGFR1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Antigen processing: Ubiquitination & Proteasome degradation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Assembly Of The HIV Virion";"IKK complex recruitment mediated by RIP1";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB2:ERBB3 signaling";"Downregulation of TGF-beta receptor signaling";"InlA-mediated entry of Listeria monocytogenes into host cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"MAPK6/MAPK4 signaling" PCG73298.1 52 Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442 "Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs" PCG71140.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" PCG68303.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG71562.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG70464.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG70694.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG75945.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" PCG78912.1 8 Reactome: R-HSA-5683826;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;Reactome: R-HSA-74217;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1 "Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Purine salvage";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II" PCG66561.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG78396.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG77769.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" PCG76080.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-2173796;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-176034;Reactome: R-HSA-674695 "Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Interactions of Tat with host cellular proteins";"RNA Polymerase II Pre-transcription Events" PCG66228.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" PCG76933.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827 "SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex" PCG70112.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG79838.1 5 MetaCyc: PWY-5074;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00281+4.1.3.4 "Mevalonate degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Synthesis and degradation of ketone bodies";"Geraniol degradation" PCG67315.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" PCG77828.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG69437.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG73577.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724 "Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" PCG63779.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" PCG78301.1 10 Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6804756 "HATs acetylate histones";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" PCG70339.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" PCG76889.1 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" PCG69348.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" PCG76322.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" PCG72421.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG80117.1 26 Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-5617472 "Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Circadian Clock";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" PCG68179.1 11 Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565 "Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" PCG75251.1 13 MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5538 "Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI" PCG73480.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" PCG80544.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" PCG68384.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation" PCG80160.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG64071.1 14 MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7589 "Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)" PCG76862.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG62432.1 17 KEGG: 05170+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1221632;Reactome: R-HSA-5685938;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616 "Human immunodeficiency virus 1 infection";"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Meiotic synapsis";"HDR through Single Strand Annealing (SSA)";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange" PCG79747.1 10 Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-1483191;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695 "Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Synthesis of PC";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Receptor Mediated Mitophagy";"Neutrophil degranulation" PCG73115.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG74783.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG71715.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG78110.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG78022.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" PCG68822.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG70223.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" PCG72114.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG70042.1 179 Reactome: R-HSA-192823;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-8863795;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-8948747;Reactome: R-HSA-912631;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-2173795;Reactome: R-HSA-8939236;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-6782210;Reactome: R-HSA-2979096;Reactome: R-HSA-168927;Reactome: R-HSA-977225;Reactome: R-HSA-2467813;Reactome: R-HSA-5696394;Reactome: R-HSA-174048;Reactome: R-HSA-69541;Reactome: R-HSA-975144;Reactome: R-HSA-182971;Reactome: R-HSA-202424;Reactome: R-HSA-6791226;Reactome: R-HSA-5357905;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-174178;Reactome: R-HSA-2173796;Reactome: R-HSA-8876493;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-5687128;Reactome: R-HSA-72689;Reactome: R-HSA-901032;Reactome: R-HSA-936440;Reactome: R-HSA-5357956;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-5696397;Reactome: R-HSA-983168;Reactome: R-HSA-9013973;Reactome: R-HSA-175474;Reactome: R-HSA-937041;Reactome: R-HSA-2173788;Reactome: R-HSA-1358803;Reactome: R-HSA-3785653;Reactome: R-HSA-5655862;Reactome: R-HSA-6804757;Reactome: R-HSA-2559585;Reactome: R-HSA-937072;Reactome: R-HSA-5693565;Reactome: R-HSA-8866652;Reactome: R-HSA-209543;Reactome: R-HSA-72706;Reactome: R-HSA-174113;Reactome: R-HSA-445989;Reactome: R-HSA-174154;Reactome: R-HSA-201681;Reactome: R-HSA-2408557;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-69231;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-2559582;Reactome: R-HSA-5675221;Reactome: R-HSA-8852276;Reactome: R-HSA-8951664;Reactome: R-HSA-1799339;Reactome: R-HSA-5654733;Reactome: R-HSA-5696395;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9020702;Reactome: R-HSA-8856828;Reactome: R-HSA-937039;Reactome: R-HSA-6807004;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-5675482;Reactome: R-HSA-9033241;Reactome: R-HSA-6782135;Reactome: R-HSA-5668541;Reactome: R-HSA-9637628;Reactome: R-HSA-9010553;Reactome: R-HSA-917937;Reactome: R-HSA-936964;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-4641263;Reactome: R-HSA-975956;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9636383;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-400253;Reactome: R-HSA-937042;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2173791;Reactome: R-HSA-5693607;Reactome: R-HSA-68949;Reactome: R-HSA-1236382;Reactome: R-HSA-9613829;Reactome: R-HSA-8875360;Reactome: R-HSA-2871837;Reactome: R-HSA-532668;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1169408;Reactome: R-HSA-5685942;Reactome: R-HSA-6781823;Reactome: R-HSA-8849469;Reactome: R-HSA-5689896;Reactome: R-HSA-2122947;Reactome: R-HSA-975110;Reactome: R-HSA-9633012;Reactome: R-HSA-3322077;Reactome: R-HSA-5632684;Reactome: R-HSA-5654727;Reactome: R-HSA-1253288;Reactome: R-HSA-2559580;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-110320;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-2691232;Reactome: R-HSA-68827;Reactome: R-HSA-72764;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-450321;Reactome: R-HSA-205043;Reactome: R-HSA-6781827;Reactome: R-HSA-3769402;Reactome: R-HSA-168638;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-2672351;Reactome: R-HSA-5689877;Reactome: R-HSA-209560;Reactome: R-HSA-8866654;Reactome: R-HSA-975163;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-9014325;Reactome: R-HSA-4641257;Reactome: R-HSA-8856825;Reactome: R-HSA-162588;Reactome: R-HSA-5696400;Reactome: R-HSA-9013507;Reactome: R-HSA-156902;Reactome: R-HSA-1295596;Reactome: R-HSA-195253;Reactome: R-HSA-5654732;Reactome: R-HSA-174490;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-6783310;Reactome: R-HSA-3134975;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-6804760;Reactome: R-HSA-450408;Reactome: R-HSA-2565942 "Viral mRNA Translation";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Downregulation of ERBB2 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Regulation of PTEN localization";"Regulation of signaling by CBL";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"TICAM1, RIP1-mediated IKK complex recruitment";"Amyloid fiber formation";"Separation of Sister Chromatids";"DNA Damage Recognition in GG-NER";"APC/C:Cdc20 mediated degradation of Cyclin B";"Stabilization of p53";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"EGFR downregulation";"Downstream TCR signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of TNFR1 signaling";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"InlA-mediated entry of Listeria monocytogenes into host cells";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"MAPK6/MAPK4 signaling";"Formation of a pool of free 40S subunits";"ER Quality Control Compartment (ERQC)";"Negative regulators of DDX58/IFIH1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1-dependent activation of IRF3/IRF7";"Assembly Of The HIV Virion";"IKK complex recruitment mediated by RIP1";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2:ERBB3 signaling";"Myoclonic epilepsy of Lafora";"Translesion synthesis by POLK";"Regulation of TP53 Degradation";"Oncogene Induced Senescence";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"p75NTR recruits signalling complexes";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SCF-beta-TrCP mediated degradation of Emi1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"APC/C:Cdc20 mediated degradation of Securin";"TCF dependent signaling in response to WNT";"Selenocysteine synthesis";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Cyclin D associated events in G1";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulation of MAPK pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neddylation";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR4 signaling";"Formation of Incision Complex in GG-NER";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Interleukin-1 signaling";"Clathrin-mediated endocytosis";"IRAK1 recruits IKK complex";"Negative regulation of MET activity";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of necroptotic cell death";"Peroxisomal protein import";"Dual incision in TC-NER";"TNFR2 non-canonical NF-kB pathway";"Modulation by Mtb of host immune system";"Regulation of expression of SLITs and ROBOs";"Iron uptake and transport";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of FZD by ubiquitination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Prevention of phagosomal-lysosomal fusion";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Circadian Clock";"IRAK2 mediated activation of TAK1 complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Processing of DNA double-strand break ends";"Orc1 removal from chromatin";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Chaperone Mediated Autophagy";"InlB-mediated entry of Listeria monocytogenes into host cell";"FCERI mediated NF-kB activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"ISG15 antiviral mechanism";"HDR through Homologous Recombination (HRR)";"Formation of TC-NER Pre-Incision Complex";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ovarian tumor domain proteases";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Glycogen synthesis";"Hedgehog 'on' state";"Negative regulation of FGFR2 signaling";"Downregulation of ERBB4 signaling";"Oxidative Stress Induced Senescence";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion Synthesis by POLH";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"CDT1 association with the CDC6:ORC:origin complex";"Eukaryotic Translation Termination";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NRIF signals cell death from the nucleus";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Deactivation of the beta-catenin transactivating complex";"NOD1/2 Signaling Pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Stimuli-sensing channels";"Josephin domain DUBs";"NF-kB is activated and signals survival";"E3 ubiquitin ligases ubiquitinate target proteins";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Metalloprotease DUBs";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Degradation of AXIN";"Cargo recognition for clathrin-mediated endocytosis";"Budding and maturation of HIV virion";"Dual Incision in GG-NER";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Peptide chain elongation";"Spry regulation of FGF signaling";"Degradation of beta-catenin by the destruction complex";"Negative regulation of FGFR3 signaling";"Membrane binding and targetting of GAG proteins";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Fanconi Anemia Pathway";"Regulation of innate immune responses to cytosolic DNA";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Regulation of TP53 Activity through Methylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PLK1 Activity at G2/M Transition" PCG70479.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG80108.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" PCG76114.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" PCG73554.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG79832.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG62754.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG76395.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG62717.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG76765.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" PCG80472.1 7 KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-6363;MetaCyc: PWY-2301 "Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis" PCG69654.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" PCG72442.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG71732.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" PCG74550.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG69402.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" PCG77148.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" PCG63823.1 8 Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-163754;Reactome: R-HSA-6791055;Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2 "TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" PCG66118.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" PCG73208.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" PCG80706.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" PCG76214.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Ub-specific processing proteases";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"TCF dependent signaling in response to WNT" PCG73495.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" PCG73876.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG79959.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG72364.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG75616.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG80890.1 11 Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912 "MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane" PCG72920.1 11 Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631 "ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility" PCG63168.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" PCG77897.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" PCG66756.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826 "4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis" PCG65427.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" PCG75856.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG75287.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" PCG79009.1 7 KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" PCG68550.1 7 Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-203927;Reactome: R-HSA-168333 "Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery" PCG79264.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG63231.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" PCG73882.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277 "G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex" PCG70519.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG67190.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" PCG65121.1 4 MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation" PCG62819.1 4 MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20 "Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism" PCG78398.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG81049.1 7 Reactome: R-HSA-5362517;KEGG: 00020+2.3.1.12;KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268 "Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism" PCG75947.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" PCG76339.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes" PCG75068.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG75027.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG72847.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" PCG78500.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG75028.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG69548.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG69262.1 3 KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669;Reactome: R-HSA-1483213 "Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE" PCG67128.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" PCG66094.1 1 Reactome: R-HSA-191859 "snRNP Assembly" PCG76300.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" PCG74085.1 7 KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7295;MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7294 "Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"D-xylose degradation IV" PCG72624.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG73359.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG66101.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" PCG66643.1 9 Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry" PCG65211.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" PCG67582.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" PCG80833.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG76477.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG74255.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG72981.1 17 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG78196.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG63259.1 6 MetaCyc: PWY-622;Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1 "Starch biosynthesis";"Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism" PCG65220.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" PCG65239.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" PCG74910.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" PCG68413.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit" PCG77985.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" PCG74079.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6 "Tryptophan metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism" PCG63236.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" PCG75302.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" PCG81042.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG66353.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" PCG69229.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" PCG69255.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" PCG73716.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" PCG71442.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" PCG71426.1 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol" PCG67680.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG75065.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG65310.1 3 Reactome: R-HSA-195399;Reactome: R-HSA-114608;Reactome: R-HSA-194313 "VEGF binds to VEGFR leading to receptor dimerization";"Platelet degranulation";"VEGF ligand-receptor interactions" PCG67613.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" PCG65441.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG72360.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG63725.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" PCG74681.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" PCG68319.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" PCG65106.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" PCG73173.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695 "Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation" PCG78553.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG69005.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" PCG73353.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport" PCG68410.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG74850.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" PCG72505.1 13 MetaCyc: PWY-7909;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722 "Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"One carbon pool by folate";"L-histidine degradation III";"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate" PCG70861.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG66557.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG69098.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG64436.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" PCG64650.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" PCG73158.1 3 Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins" PCG70482.1 7 MetaCyc: PWY-5129;MetaCyc: PWY-7836;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-7841;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism" PCG65530.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG70114.1 37 Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-9639288;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-204005;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-983170;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168333 "Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Amino acids regulate mTORC1";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"COPII-mediated vesicle transport";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery" PCG75053.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" PCG73854.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" PCG71360.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG64781.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-399997 "G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion" PCG73742.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG72839.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" PCG79506.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG73404.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG75452.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" PCG73785.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)" PCG68259.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" PCG74278.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG72677.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" PCG68589.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" PCG68174.1 12 KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476 "Human papillomavirus infection";"NRAGE signals death through JNK";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"G alpha (q) signalling events" PCG76963.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" PCG62850.1 7 MetaCyc: PWY-7198;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Thiamine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" PCG71895.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" PCG78788.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" PCG71310.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" PCG68506.1 3 Reactome: R-HSA-6806664;KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999 "Metabolism of vitamin K";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle" PCG81000.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG68120.1 40 Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-167243;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-5601884;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" PCG67419.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" PCG69403.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" PCG69416.1 5 Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-9627069 "SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity" PCG72294.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" PCG77569.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG67288.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090 "Collagen degradation";"MHC class II antigen presentation";"Neutrophil degranulation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures" PCG63600.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" PCG72021.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG69166.1 4 KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;Reactome: R-HSA-419771 "One carbon pool by folate";"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"Opsins" PCG66252.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG65417.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" PCG67484.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" PCG75958.1 7 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-140837;Reactome: R-HSA-375276;Reactome: R-HSA-8957275 "G alpha (i) signalling events";"G alpha (q) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors";"Post-translational protein phosphorylation" PCG64845.1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" PCG75709.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG67412.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" PCG72991.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG73715.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" PCG78502.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG66920.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG65349.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG64797.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG63232.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" PCG78169.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" PCG71951.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG66103.1 19 Reactome: R-HSA-194840;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-3928662;Reactome: R-HSA-182971;Reactome: R-HSA-8964616;Reactome: R-HSA-5627123;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-8950505;Reactome: R-HSA-114604 "Rho GTPase cycle";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"EPHB-mediated forward signaling";"EGFR downregulation";"G beta:gamma signalling through CDC42";"RHO GTPases activate PAKs";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade" PCG78232.1 18 Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-77075 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE" PCG70790.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" PCG66431.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG74222.1 12 MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Starch and sucrose metabolism";"Stachyose degradation" PCG74193.1 5 MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201 "Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate transformations I" PCG81078.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG74551.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG65044.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" PCG80237.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" PCG62751.1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-8862803 "Detoxification of Reactive Oxygen Species";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" PCG74249.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" PCG71646.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" PCG74580.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG65583.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" PCG64242.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" PCG67413.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" PCG78850.1 6 MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13 "L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" PCG73552.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG78427.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" PCG76676.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" PCG71528.1 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus" PCG63738.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG63677.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG80724.1 10 KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239 "Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"RSK activation";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Recycling pathway of L1" PCG79254.1 8 Reactome: R-HSA-70635;MetaCyc: PWY-7400;KEGG: 00220+4.3.2.1;MetaCyc: PWY-5154;MetaCyc: PWY-4983;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-5 "Urea cycle";"L-arginine biosynthesis IV (archaebacteria)";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Canavanine biosynthesis" PCG79776.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG75605.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" PCG72133.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG76202.1 11 Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801 "Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA replication initiation";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair" PCG68687.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG79909.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Ub-specific processing proteases";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation" PCG74918.1 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex" PCG71638.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" PCG64273.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829 "Aggrephagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy" PCG64333.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG78270.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG66932.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG77212.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG78148.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" PCG78439.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" PCG75062.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976;Reactome: R-HSA-2395516 "Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin" PCG79103.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" PCG78006.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" PCG63254.1 57 Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562 "Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FCERI mediated NF-kB activation";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)" PCG74071.1 1 Reactome: R-HSA-390696 "Adrenoceptors" PCG73833.1 5 MetaCyc: PWY-4983;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39 "Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"ROS and RNS production in phagocytes";"Arginine and proline metabolism" PCG62880.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG78855.1 6 MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-4981 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)" PCG64292.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG63092.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG69794.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG73620.1 33 Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-159230 "Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA" PCG79223.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG70122.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG72235.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-180024 "Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"DARPP-32 events" PCG79617.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" PCG75160.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Signaling by Hippo" PCG66988.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG68955.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG69363.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" PCG63654.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" PCG64657.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" PCG80111.1 26 Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-381340 "Attenuation phase";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Circadian Clock";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Transcriptional regulation of white adipocyte differentiation" PCG68487.1 4 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" PCG80114.1 26 Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3899300 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"Circadian Clock";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors" PCG68414.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG79627.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" PCG65056.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG63947.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG80242.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" PCG78869.1 2 Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" PCG76274.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" PCG68974.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG74932.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" PCG80122.1 26 Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862 "Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" PCG63519.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG70430.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" PCG63322.1 5 Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "Ub-specific processing proteases";"Protein ubiquitination";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN" PCG73253.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG65019.1 20 MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis" PCG72399.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" PCG75129.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG72475.1 10 MetaCyc: PWY-6174;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7571;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391 "Mevalonate pathway II (archaea)";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Butanoate metabolism";"Ferrichrome A biosynthesis";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)" PCG63230.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" PCG79852.1 14 MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8052 "Plasmalogen biosynthesis";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis" PCG67902.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" PCG65340.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG69070.1 7 KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-6855;Reactome: R-HSA-71336;MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6 "Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" PCG63567.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG75524.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG69493.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" PCG62899.1 13 Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52 "Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" PCG79780.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG76770.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" PCG72121.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952 "Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions" PCG79205.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG73207.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG72385.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" PCG77142.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1" PCG78128.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG81029.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-8951430 "Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling" PCG71608.1 1 Reactome: R-HSA-71288 "Creatine metabolism" PCG74076.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685 "Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species" PCG68442.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG79847.1 14 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-75109;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053 "Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Sphingolipid metabolism";"Anandamide biosynthesis II" PCG69353.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" PCG68958.1 5 Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7177;MetaCyc: PWY-7185 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I" PCG62608.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-8939236 "HDR through Single Strand Annealing (SSA)";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" PCG68971.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" PCG79399.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" PCG72307.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG73662.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG81005.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG71842.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG76604.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG74786.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG76501.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-6798695 "SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Neutrophil degranulation" PCG64735.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG79408.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG79744.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG68739.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429 "Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" PCG68426.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-8951664;Reactome: R-HSA-349425 "Protein ubiquitination";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1" PCG68422.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" PCG68844.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG64121.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142 "snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins" PCG79917.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" PCG79985.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG79234.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-9610379 "SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events" PCG69209.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" PCG80553.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG75546.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG62447.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" PCG70601.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" PCG78835.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG70500.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" PCG81069.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG74958.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230 "Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane" PCG71335.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" PCG80631.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" PCG75224.1 20 KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of TP53 Degradation";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" PCG73834.1 5 Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556 "Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Arginine and proline metabolism";"ROS and RNS production in phagocytes" PCG67120.1 16 Reactome: R-HSA-164939;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-190873;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-167590;Reactome: R-HSA-437239 "Nef mediated downregulation of CD28 cell surface expression";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"LDL clearance";"Gap junction degradation";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1" PCG69475.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-9609690 "Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events" PCG79154.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG64993.1 6 KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;MetaCyc: PWY-6368;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol" PCG70883.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG62935.1 6 MetaCyc: PWY-6907;MetaCyc: PWY-6908;MetaCyc: PWY-7356;Reactome: R-HSA-196819;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine metabolism" PCG72209.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG76054.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG66968.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG71957.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" PCG72419.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" PCG67144.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" PCG67307.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG76769.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" PCG63939.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG78220.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway" PCG78852.1 6 MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism" PCG78055.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG73484.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG71110.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" PCG64586.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG71902.1 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" PCG76834.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-9610379 "Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events" PCG77781.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG68513.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" PCG72982.1 17 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG75123.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG71865.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG72471.1 5 KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22 "Galactose metabolism";"Sphingolipid metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" PCG70460.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" PCG71878.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG74470.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG70204.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" PCG63084.1 5 MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-5269 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Synthesis of PG";"Cardiolipin biosynthesis II" PCG79466.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG76248.1 1 Reactome: R-HSA-211981 "Xenobiotics" PCG73597.1 5 MetaCyc: PWY-5514;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)" PCG65046.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG77611.1 16 MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.4;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II" PCG67750.1 8 Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724 "SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription" PCG74018.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" PCG68548.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" PCG74254.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" PCG74526.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG78290.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" PCG71479.1 16 Reactome: R-HSA-6796648;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167238 "TP53 Regulates Transcription of DNA Repair Genes";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation" PCG80520.1 4 Reactome: R-HSA-383280;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Nuclear Receptor transcription pathway";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" PCG69892.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG79979.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG78095.1 9 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" PCG69826.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5972 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)" PCG64092.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG78437.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG63289.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" PCG75051.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG75286.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" PCG74957.1 8 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" PCG74924.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025 "Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Aggrephagy";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation" PCG76873.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG69685.1 8 MetaCyc: PWY-7733;MetaCyc: PWY-7717;MetaCyc: PWY-5651;KEGG: 00630+3.5.1.9;MetaCyc: PWY-6309;MetaCyc: PWY-7765;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7734 "3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism";"Quinoxaline-2-carboxylate biosynthesis" PCG65731.1 31 MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-8047;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-6113;MetaCyc: PWY-5366;MetaCyc: PWY-7858;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5973;MetaCyc: PWY-5367;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;MetaCyc: PWY-6282 "8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Cis-vaccenate biosynthesis";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)" PCG78562.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG72178.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" PCG69433.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG64865.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG72817.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" PCG73693.1 4 KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183 "Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol" PCG63641.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" PCG74425.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG77477.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001 "MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism" PCG69025.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG71213.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG64884.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" PCG80047.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" PCG73041.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" PCG76917.1 57 Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785 "Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Neddylation";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome" PCG79815.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport" PCG80267.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG66916.1 12 Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-75955 "Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation" PCG70105.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" PCG75082.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" PCG79977.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG66433.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" PCG75435.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG70562.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" PCG81070.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG68042.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590 "Amino acids regulate mTORC1";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation" PCG65236.1 1 Reactome: R-HSA-5689603 "UCH proteinases" PCG66749.1 12 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-381038;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"XBP1(S) activates chaperone genes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane" PCG66642.1 9 Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1" PCG76230.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" PCG75236.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG75943.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-426496 "MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs" PCG64793.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG73317.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-210744 "RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" PCG71876.1 1 Reactome: R-HSA-191859 "snRNP Assembly" PCG72130.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG63118.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" PCG67852.1 22 Reactome: R-HSA-9648025;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-2500257;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337 "EML4 and NUDC in mitotic spindle formation";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"Resolution of Sister Chromatid Cohesion";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding" PCG81007.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs" PCG80948.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" PCG71172.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG64763.1 20 KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7291 "Fatty acid degradation";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)" PCG66104.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" PCG64447.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG76225.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" PCG78229.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" PCG73661.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG71847.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling" PCG73143.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG78379.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" PCG77478.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662 "MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism" PCG74758.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG77143.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade" PCG76495.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" PCG78016.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" PCG69847.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG76680.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" PCG67951.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" PCG70571.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" PCG80987.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG77999.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" PCG77533.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG73591.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG76663.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" PCG66014.1 12 KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4 "Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" PCG77586.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" PCG68635.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" PCG73610.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" PCG76082.1 9 Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-75955 "Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation" PCG74892.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG71095.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG69308.1 8 Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-8941284;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838 "Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"RUNX2 regulates chondrocyte maturation";"Ligand-receptor interactions";"Hedgehog 'on' state";"Activation of SMO" PCG77840.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" PCG62448.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" PCG76878.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG70939.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG65865.1 5 Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661 "Proline catabolism";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation" PCG69971.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" PCG79777.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG74898.1 17 Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-1912408;Reactome: R-HSA-111448;Reactome: R-HSA-69231;Reactome: R-HSA-2559580;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-8953750;Reactome: R-HSA-139915;Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-69656;Reactome: R-HSA-9616222;Reactome: R-HSA-2173796;Reactome: R-HSA-2559585 "Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"Pre-NOTCH Transcription and Translation";"Activation of NOXA and translocation to mitochondria";"Cyclin D associated events in G1";"Oxidative Stress Induced Senescence";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcriptional Regulation by E2F6";"Activation of PUMA and translocation to mitochondria";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional regulation of granulopoiesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oncogene Induced Senescence" PCG80826.1 13 Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-2261;MetaCyc: PWY-6370 "Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)" PCG63418.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG79996.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" PCG70300.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" PCG70393.1 7 Reactome: R-HSA-2470946;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Cohesin Loading onto Chromatin";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" PCG69346.1 12 KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-5870;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-7230 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)" PCG77124.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG64051.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" PCG75526.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG74270.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG79928.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG80528.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" PCG80872.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" PCG68157.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" PCG64542.1 11 MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;MetaCyc: PWY-381;MetaCyc: PWY-6963;MetaCyc: PWY-6549;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2 "Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism" PCG79800.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" PCG65442.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG76984.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D" PCG77984.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" PCG62944.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" PCG70568.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" PCG70071.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG73801.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" PCG63143.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG68417.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" PCG77859.1 1 Reactome: R-HSA-525793 "Myogenesis" PCG63837.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" PCG75241.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG64792.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG66917.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events" PCG78189.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG76601.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG70334.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG68794.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" PCG68758.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" PCG79105.1 9 Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783 "Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type" PCG63862.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG70089.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" PCG70101.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" PCG65224.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG76999.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" PCG64839.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG67958.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" PCG68276.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" PCG66571.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG69655.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" PCG68685.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG70698.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" PCG79623.1 2 KEGG: 00500+3.2.1.26;KEGG: 00052+3.2.1.26 "Starch and sucrose metabolism";"Galactose metabolism" PCG63032.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG73350.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG72342.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" PCG69886.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG74790.1 7 Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724 "Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription" PCG74050.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" PCG75203.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" PCG65505.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785 "Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome" PCG63033.1 22 MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7727;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7606 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" PCG79921.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG63113.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277 "Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" PCG64334.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG74191.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG62628.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" PCG74462.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG75949.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" PCG76937.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG67784.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-450520;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion" PCG78009.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" PCG62756.1 6 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-622 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Starch biosynthesis" PCG73389.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-110329;Reactome: R-HSA-9630222;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" PCG79918.1 8 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-5689880;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" PCG63203.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination" PCG63593.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" PCG69077.1 11 Reactome: R-HSA-2173796;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-72163;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription" PCG69023.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG72363.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG77214.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" PCG69435.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG76858.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG79810.1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507 "Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" PCG66074.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG65267.1 6 MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686 "UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis I" PCG71203.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" PCG66507.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG76139.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG76112.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" PCG63825.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG76919.1 4 KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" PCG78847.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG65188.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685;Reactome: R-HSA-5628897 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes" PCG80883.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG71537.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG72017.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG65418.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase" PCG77509.1 12 MetaCyc: PWY-6142;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-1861 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" PCG74795.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG70674.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG69905.1 11 Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation" PCG79849.1 14 MetaCyc: PWY-6453;Reactome: R-HSA-75109;MetaCyc: PWY-7782;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8052;Reactome: R-HSA-1483191 "Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis I";"Synthesis of PE";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC" PCG65908.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" PCG70084.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" PCG79143.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" PCG66618.1 57 Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178 "Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Ub-specific processing proteases";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" PCG72621.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" PCG71587.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" PCG73614.1 29 Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6782210 "RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER" PCG79202.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" PCG75737.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG67654.1 6 MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151 "Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" PCG65361.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG77746.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" PCG65601.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG63243.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" PCG75781.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" PCG78963.1 31 MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-6113;MetaCyc: PWY-7746;MetaCyc: PWY-5147;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;MetaCyc: PWY-8047;MetaCyc: PWY-7663;MetaCyc: PWYG-321;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-6519;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14 "(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Superpathway of mycolate biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Bryostatin biosynthesis";"Gondoate biosynthesis (anaerobic)";"";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis" PCG72473.1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527 "Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Stachyose degradation" PCG70068.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG70478.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG74600.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" PCG74563.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG63311.1 3 Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096 "MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation" PCG80105.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG76593.1 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol" PCG78594.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG79074.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG77283.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" PCG65513.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" PCG67471.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG77627.1 40 Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167242 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat" PCG79646.1 8 Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" PCG79374.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG66150.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" PCG69763.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" PCG77484.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG72633.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" PCG80974.1 5 Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-936440 "ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling" PCG70932.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG69941.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG74453.1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" PCG63940.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG79519.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG64911.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG76242.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" PCG80775.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG66677.1 7 Reactome: R-HSA-6782315;Reactome: R-HSA-379716;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15 "tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" PCG75227.1 8 KEGG: 00240+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7199;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-6556 "Pyrimidine metabolism";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II" PCG68586.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG66423.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG70471.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" PCG62572.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" PCG64086.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" PCG72472.1 5 MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22 "Stachyose degradation";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism" PCG74889.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" PCG72260.1 29 Reactome: R-HSA-73772;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167200 "RNA Polymerase I Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat" PCG74845.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG70863.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" PCG73806.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" PCG66975.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" PCG80207.1 5 KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;Reactome: R-HSA-532668 "N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" PCG73765.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" PCG78264.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" PCG68915.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG62470.1 14 MetaCyc: PWY-7003;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5484 "Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)" PCG67627.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG79536.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" PCG67857.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" PCG71812.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG75711.1 12 MetaCyc: PWY-6309;KEGG: 00450+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-2821;MetaCyc: PWY-1187;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Selenocompound metabolism";"Tryptophan catabolism";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II";"Tryptophan metabolism" PCG63791.1 7 Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "UCH proteinases";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" PCG68642.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" PCG72995.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG80180.1 10 MetaCyc: PWY-7909;MetaCyc: PWY-5030;MetaCyc: PWY-6613;MetaCyc: PWY-3841;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722 "Formaldehyde oxidation VII (THF pathway)";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Folate transformations I";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate" PCG65025.1 3 Reactome: R-HSA-71262;MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8 "Carnitine synthesis";"L-carnitine biosynthesis";"Lysine degradation" PCG74961.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" PCG66562.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG77497.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-3214841;Reactome: R-HSA-6804760 "Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation" PCG75769.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" PCG79471.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG75641.1 10 MetaCyc: PWY-7587;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-5667 "Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I" PCG65251.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging" PCG80627.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG68953.1 6 MetaCyc: PWY-5514;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" PCG72926.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG64053.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" PCG73595.1 20 Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121 "Dual Incision in GG-NER";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI" PCG68246.1 8 Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Photosynthesis";"ATP biosynthesis";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" PCG63283.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" PCG66123.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG78681.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG62471.1 14 MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11 "1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Methane metabolism";"Rubisco shunt";"Glycolysis / Gluconeogenesis" PCG68385.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" PCG76276.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG77796.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" PCG65927.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG77141.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964 "MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" PCG70249.1 14 Reactome: R-HSA-418217;Reactome: R-HSA-112043;Reactome: R-HSA-416476;Reactome: R-HSA-399997;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-434316;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-500657;Reactome: R-HSA-4086398 "G beta:gamma signalling through PLC beta";"PLC beta mediated events";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"Ca2+ pathway" PCG80172.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" PCG76048.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG75342.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG76527.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" PCG70862.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG64113.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG75635.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG67066.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68689 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex" PCG72927.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG70602.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" PCG72355.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG66704.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG78384.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" PCG63513.1 10 MetaCyc: PWY-6613;KEGG: 00670+2.1.2.2;KEGG: 00970+2.1.2.9;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6277 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" PCG78705.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" PCG75247.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-6502 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I" PCG78941.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG79115.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" PCG63663.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" PCG76174.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG79855.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG75013.1 16 Reactome: R-HSA-69473;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-9018519;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568 "G2/M DNA damage checkpoint";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates" PCG65821.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" PCG68357.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" PCG65186.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" PCG71564.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG67025.1 8 MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" PCG74554.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG71059.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" PCG64662.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" PCG79244.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG70086.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis" PCG67353.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG80040.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG68837.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG81094.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" PCG67677.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)" PCG66522.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG77364.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" PCG62451.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG73813.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" PCG65113.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" PCG74375.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" PCG71543.1 1 Reactome: R-HSA-376172 "DSCAM interactions" PCG78627.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" PCG79667.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" PCG78008.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" PCG69662.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG63902.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" PCG73427.1 5 KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome" PCG79230.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG73117.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG80191.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG71480.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" PCG72276.1 9 Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791 "TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"UCH proteinases";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" PCG78468.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436 "Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic" PCG74215.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" PCG78077.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" PCG68290.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG74380.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG71954.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG73814.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" PCG81060.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" PCG72443.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG64245.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" PCG80837.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG79978.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG72553.1 8 KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1 "Glycolysis / Gluconeogenesis";"Glycolysis";"Galactose metabolism";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis" PCG64936.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG75508.1 12 MetaCyc: PWY-8051;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783 "Anandamide biosynthesis I";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation" PCG67882.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG80836.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG75280.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" PCG72316.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" PCG81114.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" PCG65671.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" PCG68389.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" PCG78786.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" PCG78516.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG63147.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG62648.1 4 Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" PCG72386.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" PCG68125.1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG69063.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG67687.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG75503.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" PCG77873.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG77830.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" PCG68634.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" PCG64443.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG78186.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" PCG64947.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG77838.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG65290.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG66151.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG79773.1 4 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69205 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"G1/S-Specific Transcription" PCG74475.1 14 Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-6798695;Reactome: R-HSA-1474228;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2122948 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Neutrophil degranulation";"Degradation of the extracellular matrix";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus" PCG78428.1 7 KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" PCG76552.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG69552.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG75683.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-442982 "RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor" PCG75084.1 5 MetaCyc: PWY-5531;MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37 "3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism" PCG77864.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" PCG75228.1 20 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Regulation of TP53 Degradation";"mTOR signalling";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"Thermogenesis";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG78102.1 1 Reactome: R-HSA-191859 "snRNP Assembly" PCG74555.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG79661.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" PCG67570.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" PCG62581.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" PCG74250.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" PCG68516.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG69269.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" PCG80880.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" PCG74764.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" PCG65002.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" PCG70585.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG70171.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Insulin receptor recycling";"ROS and RNS production in phagocytes" PCG74913.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" PCG72291.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" PCG79873.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG66199.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199 "Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation" PCG80530.1 11 MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-6999;Reactome: R-HSA-8851680;MetaCyc: PWY-6596;MetaCyc: PWY-6538;MetaCyc: PWY-5695;MetaCyc: PWY-6608;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;Reactome: R-HSA-74259 "Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Theophylline degradation";"Butyrophilin (BTN) family interactions";"Adenosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation I";"Purine catabolism" PCG72105.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8951664 "Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Neddylation" PCG70330.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" PCG74063.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG65166.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG78397.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" PCG73857.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" PCG80813.1 10 Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" PCG79503.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG75454.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" PCG73859.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG64570.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG70501.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" PCG80081.1 6 Reactome: R-HSA-5632684;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654 "Hedgehog 'on' state";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins" PCG74846.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" PCG64513.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG79504.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG79745.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6804756;Reactome: R-HSA-445144 "Neutrophil degranulation";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1" PCG74709.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" PCG63129.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG65733.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" PCG63313.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" PCG77971.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation" PCG74381.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG63996.1 8 Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;Reactome: R-HSA-9619483 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs" PCG67900.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG71647.1 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism" PCG68745.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG71771.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG80921.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" PCG64675.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling" PCG75549.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" PCG79375.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG66931.1 3 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;KEGG: 00970+6.3.5.7 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Aminoacyl-tRNA biosynthesis" PCG65753.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG64193.1 6 Reactome: R-HSA-5358606;Reactome: R-HSA-5632928;Reactome: R-HSA-6796648;Reactome: R-HSA-5632968;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" PCG74628.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG67253.1 33 Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-8939236;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-69231;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-69273;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-6782135 "Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Cyclin D associated events in G1";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"Dual incision in TC-NER" PCG78079.1 5 MetaCyc: PWY-5532;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614 "Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage" PCG76910.1 8 MetaCyc: PWY-6664;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-2301;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4 "Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis" PCG67290.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695 "MHC class II antigen presentation";"Collagen degradation";"Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation" PCG71202.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" PCG63284.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" PCG64639.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG71689.1 15 Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174048 "APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B" PCG78566.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG72648.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" PCG75638.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG72880.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" PCG77269.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG74760.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" PCG77463.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" PCG70161.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG77301.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG67901.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" PCG69968.1 8 MetaCyc: PWY-7198;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" PCG69891.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG66243.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG68378.1 4 Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781 "tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis" PCG66117.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" PCG67161.1 6 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" PCG77074.1 19 Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7220 "Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II" PCG73962.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-139853;Reactome: R-HSA-5607763 "DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Ion homeostasis";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation" PCG72707.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG69736.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" PCG80301.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432720 "Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" PCG68469.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" PCG71170.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG69786.1 20 Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801 "Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair" PCG64080.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" PCG62469.1 14 MetaCyc: PWY-6886;MetaCyc: PWY-1622;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-8004;KEGG: 00680+4.2.1.11;MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11 "1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway I";"Methane metabolism";"Rubisco shunt";"Glycolysis / Gluconeogenesis" PCG75070.1 13 Reactome: R-HSA-6802955;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"PI3K-Akt signaling pathway";"Signaling downstream of RAS mutants";"Relaxin signaling pathway";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"mTOR signaling pathway";"Thermogenesis" PCG74022.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" PCG76198.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" PCG63930.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" PCG71798.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG77750.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids" PCG78211.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG68570.1 52 Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-5578749;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-749476;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-5601884;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-6807505;Reactome: R-HSA-73762;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-112382;Reactome: R-HSA-73780;Reactome: R-HSA-9018519;Reactome: R-HSA-167200 "MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Transcriptional regulation by small RNAs";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"PIWI-interacting RNA (piRNA) biogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Chain Elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat" PCG70057.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" PCG75803.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG62657.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG73234.1 10 Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-983231;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017 "Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" PCG70640.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" PCG64115.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG72455.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG64646.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" PCG69728.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG65015.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7007;MetaCyc: PWY-6837 "alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)" PCG63758.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG64454.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" PCG76153.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG71471.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" PCG70265.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG63552.1 5 MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7 "Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis" PCG76579.1 1 Reactome: R-HSA-400253 "Circadian Clock" PCG66216.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG69600.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG71199.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" PCG63412.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" PCG66644.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG74135.1 8 KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1 "Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" PCG64713.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG76714.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" PCG74573.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG79737.1 5 MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation" PCG65064.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG71080.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG78791.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG64818.1 19 Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041 "Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Chylomicron remodeling";"VLDL clearance";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"VLDL assembly";"LDL remodeling" PCG71086.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG66976.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" PCG76823.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" PCG64453.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" PCG79023.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" PCG76939.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG69088.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG64724.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG72252.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG73647.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" PCG75449.1 18 KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1 "Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Tyrosine metabolism";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism" PCG74118.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG65136.1 6 KEGG: 04070+3.1.3.64;Reactome: R-HSA-1660517;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)" PCG80036.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG67805.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG64214.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis" PCG72365.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" PCG78207.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" PCG81064.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" PCG79139.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" PCG68190.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG71217.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" PCG65607.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" PCG79144.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" PCG77406.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG71554.1 27 Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-9610379 "SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events" PCG69759.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" PCG74842.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG72997.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" PCG62477.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG79629.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" PCG78046.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG71668.1 6 MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221 "Sorbitol biosynthesis II";"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)" PCG81016.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" PCG75719.1 1 Reactome: R-HSA-5635838 "Activation of SMO" PCG71501.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG67381.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG71200.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" PCG81130.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" PCG66057.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8957275 "LDL remodeling";"VLDL assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"LDL clearance";"VLDL clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Chylomicron remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation" PCG72426.1 1 Reactome: R-HSA-912446 "Meiotic recombination" PCG76305.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" PCG67448.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II" PCG81101.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" PCG79185.1 1 Reactome: R-HSA-1296061 "HCN channels" PCG77099.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG63185.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG63945.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG80151.1 10 MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-6886;Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-1042 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)" PCG78438.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" PCG77389.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG74920.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" PCG65761.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" PCG64402.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" PCG79317.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" PCG79914.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Dual incision in TC-NER";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex" PCG65456.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG76486.1 24 Reactome: R-HSA-6804757;Reactome: R-HSA-354192;Reactome: R-HSA-5607764;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5625740;Reactome: R-HSA-9634635;Reactome: R-HSA-165158;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-2730905;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1 "Regulation of TP53 Degradation";"Integrin signaling";"CLEC7A (Dectin-1) signaling";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"RSK activation";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"FCERI mediated NF-kB activation";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"RHO GTPases activate PKNs";"Estrogen-stimulated signaling through PRKCZ";"Activation of AKT2";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway" PCG73527.1 16 Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-1963640;Reactome: R-HSA-6811558;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-1251985;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565 "Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"GRB2 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"Nuclear signaling by ERBB4";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants" PCG64864.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" PCG79582.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" PCG65374.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" PCG80556.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG64403.1 6 MetaCyc: PWY-6606;MetaCyc: PWY-5497;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259 "Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism" PCG74100.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" PCG78191.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG67062.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" PCG69549.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG64049.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" PCG64269.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" PCG72536.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG79938.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" PCG66912.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" PCG74051.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" PCG76616.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" PCG71500.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" PCG74603.1 14 KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5101;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5108;Reactome: R-HSA-70895;MetaCyc: PWY-5104;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5103;KEGG: 00966+2.6.1.42;KEGG: 00290+2.6.1.42 "Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis IV";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"L-isoleucine degradation II";"L-isoleucine biosynthesis III";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine biosynthesis" PCG70308.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG70147.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG74184.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG76254.1 26 Reactome: R-HSA-8852276;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Post-chaperonin tubulin folding pathway";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins" PCG63931.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG64052.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" PCG63824.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG71410.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" PCG79772.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295 "Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation" PCG80206.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG68759.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" PCG76589.1 29 Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648 "RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes" PCG72224.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG62662.1 28 Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-912446;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-3371511;Reactome: R-HSA-5358606;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400 "Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Meiotic recombination";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HSF1 activation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER" PCG68643.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" PCG77226.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG80251.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" PCG76407.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" PCG75324.1 6 Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;Reactome: R-HSA-5693565;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "ESR-mediated signaling";"Negative regulation of MAPK pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG76391.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" PCG69689.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG62914.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" PCG75610.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" PCG69069.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" PCG80417.1 5 Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC" PCG78166.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" PCG74981.1 14 Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-6969 "Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" PCG63253.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG63184.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG73031.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" PCG80110.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Circadian Clock";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation" PCG67322.1 9 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG66451.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" PCG74400.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" PCG77896.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" PCG72155.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG71785.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)" PCG76699.1 6 Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" PCG74887.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" PCG73805.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" PCG66708.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" PCG69349.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" PCG71576.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" PCG63017.1 1 Reactome: R-HSA-3295583 "TRP channels" PCG69576.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG67407.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG77831.1 13 Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-3000171 "NCAM1 interactions";"ECM proteoglycans";"Extracellular matrix organization";"Collagen degradation";"Anchoring fibril formation";"Laminin interactions";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Collagen chain trimerization";"Signaling by PDGF";"Non-integrin membrane-ECM interactions" PCG73796.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG72457.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG80905.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" PCG63829.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG75405.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" PCG76394.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG77993.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG71660.1 182 Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5656169;Reactome: R-HSA-5357905;Reactome: R-HSA-5656121;Reactome: R-HSA-6791226;Reactome: R-HSA-5696394;Reactome: R-HSA-2467813;Reactome: R-HSA-977225;Reactome: R-HSA-168927;Reactome: R-HSA-182971;Reactome: R-HSA-975144;Reactome: R-HSA-174048;Reactome: R-HSA-69541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-8939236;Reactome: R-HSA-2173795;Reactome: R-HSA-912631;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-2979096;Reactome: R-HSA-6782210;Reactome: R-HSA-8863795;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-192823;Reactome: R-HSA-8948747;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-175474;Reactome: R-HSA-9013973;Reactome: R-HSA-983168;Reactome: R-HSA-5696397;Reactome: R-HSA-1358803;Reactome: R-HSA-2173788;Reactome: R-HSA-3785653;Reactome: R-HSA-937041;Reactome: R-HSA-5357956;Reactome: R-HSA-936440;Reactome: R-HSA-901032;Reactome: R-HSA-72689;Reactome: R-HSA-5654726;Reactome: R-HSA-72649;Reactome: R-HSA-168928;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-6804756;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-72702;Reactome: R-HSA-8876493;Reactome: R-HSA-2173796;Reactome: R-HSA-5675221;Reactome: R-HSA-8852276;Reactome: R-HSA-69231;Reactome: R-HSA-110314;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-2408557;Reactome: R-HSA-2559582;Reactome: R-HSA-110312;Reactome: R-HSA-174154;Reactome: R-HSA-201681;Reactome: R-HSA-5693565;Reactome: R-HSA-937072;Reactome: R-HSA-8866652;Reactome: R-HSA-2559585;Reactome: R-HSA-6804757;Reactome: R-HSA-5655862;Reactome: R-HSA-445989;Reactome: R-HSA-174113;Reactome: R-HSA-72706;Reactome: R-HSA-209543;Reactome: R-HSA-5668541;Reactome: R-HSA-6782135;Reactome: R-HSA-9637628;Reactome: R-HSA-975957;Reactome: R-HSA-9033241;Reactome: R-HSA-5675482;Reactome: R-HSA-156827;Reactome: R-HSA-937039;Reactome: R-HSA-8856828;Reactome: R-HSA-9020702;Reactome: R-HSA-72695;Reactome: R-HSA-6807004;Reactome: R-HSA-1799339;Reactome: R-HSA-8951664;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-5696395;Reactome: R-HSA-5654733;Reactome: R-HSA-2122948;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-937042;Reactome: R-HSA-975956;Reactome: R-HSA-4641263;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-9636383;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-936964;Reactome: R-HSA-917937;Reactome: R-HSA-9010553;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-110320;Reactome: R-HSA-187577;Reactome: R-HSA-1253288;Reactome: R-HSA-2559580;Reactome: R-HSA-5632684;Reactome: R-HSA-5654727;Reactome: R-HSA-3322077;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-2894862;Reactome: R-HSA-532668;Reactome: R-HSA-975110;Reactome: R-HSA-9633012;Reactome: R-HSA-2122947;Reactome: R-HSA-8849469;Reactome: R-HSA-5685942;Reactome: R-HSA-5689896;Reactome: R-HSA-6781823;Reactome: R-HSA-1169408;Reactome: R-HSA-1236382;Reactome: R-HSA-68949;Reactome: R-HSA-5693607;Reactome: R-HSA-2173791;Reactome: R-HSA-2871837;Reactome: R-HSA-8875360;Reactome: R-HSA-9613829;Reactome: R-HSA-5689901;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-975163;Reactome: R-HSA-4641257;Reactome: R-HSA-9014325;Reactome: R-HSA-1236974;Reactome: R-HSA-5205685;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-168638;Reactome: R-HSA-3769402;Reactome: R-HSA-6781827;Reactome: R-HSA-8866654;Reactome: R-HSA-209560;Reactome: R-HSA-2672351;Reactome: R-HSA-5689877;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-205043;Reactome: R-HSA-450321;Reactome: R-HSA-68827;Reactome: R-HSA-2691232;Reactome: R-HSA-72764;Reactome: R-HSA-450408;Reactome: R-HSA-2565942;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-6783310;Reactome: R-HSA-3134975;Reactome: R-HSA-5607761;Reactome: R-HSA-6804760;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-174490;Reactome: R-HSA-5654732;Reactome: R-HSA-162588;Reactome: R-HSA-5696400;Reactome: R-HSA-8856825;Reactome: R-HSA-1295596;Reactome: R-HSA-156902;Reactome: R-HSA-9013507 "Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Termination of translesion DNA synthesis";"Regulation of TNFR1 signaling";"Translesion synthesis by POLI";"Major pathway of rRNA processing in the nucleolus and cytosol";"DNA Damage Recognition in GG-NER";"Separation of Sister Chromatids";"Amyloid fiber formation";"TICAM1, RIP1-mediated IKK complex recruitment";"EGFR downregulation";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Stabilization of p53";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of signaling by CBL";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Downregulation of ERBB2 signaling";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Viral mRNA Translation";"Regulation of PTEN localization";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Assembly Of The HIV Virion";"TICAM1-dependent activation of IRF3/IRF7";"Antigen processing: Ubiquitination & Proteasome degradation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Downregulation of ERBB2:ERBB3 signaling";"Downregulation of TGF-beta receptor signaling";"Myoclonic epilepsy of Lafora";"IKK complex recruitment mediated by RIP1";"TNFR1-induced NFkappaB signaling pathway";"Negative regulators of DDX58/IFIH1 signaling";"ER Quality Control Compartment (ERQC)";"Formation of a pool of free 40S subunits";"Negative regulation of FGFR1 signaling";"Translation initiation complex formation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of TP53 Activity through Phosphorylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Ribosomal scanning and start codon recognition";"InlA-mediated entry of Listeria monocytogenes into host cells";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulation of MAPK pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cyclin D associated events in G1";"Recognition of DNA damage by PCNA-containing replication complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Selenocysteine synthesis";"Senescence-Associated Secretory Phenotype (SASP)";"Translesion synthesis by REV1";"APC/C:Cdc20 mediated degradation of Securin";"TCF dependent signaling in response to WNT";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Oncogene Induced Senescence";"Regulation of TP53 Degradation";"Translesion synthesis by POLK";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"SCF-beta-TrCP mediated degradation of Emi1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"p75NTR recruits signalling complexes";"TNFR2 non-canonical NF-kB pathway";"Dual incision in TC-NER";"Modulation by Mtb of host immune system";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peroxisomal protein import";"Regulation of necroptotic cell death";"L13a-mediated translational silencing of Ceruloplasmin expression";"IRAK1 recruits IKK complex";"Clathrin-mediated endocytosis";"Interleukin-1 signaling";"Formation of the ternary complex, and subsequently, the 43S complex";"Negative regulation of MET activity";"SRP-dependent cotranslational protein targeting to membrane";"Neddylation";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Formation of Incision Complex in GG-NER";"Negative regulation of FGFR4 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"IRAK2 mediated activation of TAK1 complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of FZD by ubiquitination";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Prevention of phagosomal-lysosomal fusion";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Iron uptake and transport";"Regulation of expression of SLITs and ROBOs";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Translesion Synthesis by POLH";"SCF(Skp2)-mediated degradation of p27/p21";"Downregulation of ERBB4 signaling";"Oxidative Stress Induced Senescence";"Hedgehog 'on' state";"Negative regulation of FGFR2 signaling";"Glycogen synthesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"NOTCH1 Intracellular Domain Regulates Transcription";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"HDR through Homologous Recombination (HRR)";"Ovarian tumor domain proteases";"Formation of TC-NER Pre-Incision Complex";"ISG15 antiviral mechanism";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Orc1 removal from chromatin";"Processing of DNA double-strand break ends";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"FCERI mediated NF-kB activation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Chaperone Mediated Autophagy";"Metalloprotease DUBs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of AXIN";"TICAM1,TRAF6-dependent induction of TAK1 complex";"ER-Phagosome pathway";"Pink/Parkin Mediated Mitophagy";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"NOD1/2 Signaling Pathway";"Deactivation of the beta-catenin transactivating complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"E3 ubiquitin ligases ubiquitinate target proteins";"NF-kB is activated and signals survival";"Stimuli-sensing channels";"Josephin domain DUBs";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"NRIF signals cell death from the nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"CDT1 association with the CDC6:ORC:origin complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Eukaryotic Translation Termination";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PLK1 Activity at G2/M Transition";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Fanconi Anemia Pathway";"Regulation of innate immune responses to cytosolic DNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of TP53 Activity through Methylation";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR3 signaling";"Budding and maturation of HIV virion";"Dual Incision in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Spry regulation of FGF signaling";"Peptide chain elongation";"NOTCH3 Activation and Transmission of Signal to the Nucleus" PCG67754.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG73914.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG72779.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" PCG72354.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG66871.1 7 Reactome: R-HSA-8950505;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" PCG65492.1 4 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" PCG69719.1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300 "Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors" PCG78183.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" PCG71249.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-975138;Reactome: R-HSA-6799198;Reactome: R-HSA-975871 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane" PCG73038.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG67223.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-912446 "Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination" PCG65957.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG80531.1 14 MetaCyc: PWY-6607;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;KEGG: 00232+1.17.3.2;MetaCyc: PWY-5497;Reactome: R-HSA-8851680;MetaCyc: PWY-6596;MetaCyc: PWY-6538;MetaCyc: PWY-6999;KEGG: 00230+1.17.1.4+1.17.3.2;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00983+1.17.3.2;MetaCyc: PWY-5695 "Guanosine nucleotides degradation I";"Purine metabolism";"Purine catabolism";"Caffeine metabolism";"Purine nucleobases degradation II (anaerobic)";"Butyrophilin (BTN) family interactions";"Adenosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Theophylline degradation";"Purine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Drug metabolism - other enzymes";"Inosine 5'-phosphate degradation" PCG76664.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" PCG78417.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" PCG78526.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway" PCG73709.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG70617.1 6 MetaCyc: PWY-2942;KEGG: 00300+4.3.3.7;MetaCyc: PWY-8088;KEGG: 00261+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-5097 "L-lysine biosynthesis III";"Lysine biosynthesis";"Dipicolinate biosynthesis";"Monobactam biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis VI" PCG69869.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG71196.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" PCG67793.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" PCG68475.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" PCG69307.1 7 Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-373080 "Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Activation of SMO";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)" PCG64117.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG76226.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" PCG75773.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG62611.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" PCG72103.1 2 Reactome: R-HSA-211945;Reactome: R-HSA-3299685 "Phase I - Functionalization of compounds";"Detoxification of Reactive Oxygen Species" PCG81041.1 17 Reactome: R-HSA-5357956;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-975163;Reactome: R-HSA-202424;Reactome: R-HSA-9014325;Reactome: R-HSA-4086398;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-937072;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-450321 "TNFR1-induced NFkappaB signaling pathway";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Downstream TCR signaling";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ca2+ pathway";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" PCG68825.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG78624.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation" PCG76442.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG65252.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinamide salvaging" PCG72535.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" PCG66481.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" PCG70183.1 13 MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7721 "Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis" PCG79249.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition" PCG74036.1 6 Reactome: R-HSA-71403;KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Mitochondrial protein import" PCG75912.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" PCG73410.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" PCG75639.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG80903.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" PCG79851.1 14 Reactome: R-HSA-1483191;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00561+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;Reactome: R-HSA-75109 "Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Ether lipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Synthesis of PE";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Triglyceride biosynthesis" PCG75301.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG71832.1 32 Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6803529;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-73779 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" PCG79207.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG68804.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG79263.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG72533.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" PCG74243.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" PCG64935.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG79036.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" PCG72350.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG65790.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" PCG73333.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport" PCG71176.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG68450.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897;Reactome: R-HSA-198323 "Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol" PCG76433.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG70113.1 11 Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174430 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation" PCG77209.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG67235.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG75307.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG75221.1 2 Reactome: R-HSA-71336;KEGG: 00710+2.7.1.14 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms" PCG73114.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG65146.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG75144.1 10 Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111457 "Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria" PCG72815.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" PCG78445.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG72495.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" PCG72293.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" PCG71725.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" PCG71097.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" PCG74833.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" PCG72708.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG63018.1 12 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6804756;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-674695 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events" PCG78676.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG64215.1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-8053 "Synthesis of PA";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II" PCG77410.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG65945.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" PCG78141.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG77510.1 12 MetaCyc: PWY-7385;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms" PCG80853.1 13 KEGG: 00740+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00240+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9 "Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Purine catabolism";"Starch and sucrose metabolism" PCG75602.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" PCG80202.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG78853.1 6 MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344 "L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" PCG72306.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG68464.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG70394.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" PCG67895.1 15 MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6901;KEGG: 00010+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-7003 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Rubisco shunt";"Purine metabolism";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol" PCG80776.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG69125.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG66591.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Photosynthesis" PCG76328.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG74223.1 12 MetaCyc: PWY-3801;MetaCyc: PWY-7817;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077 "Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Starch and sucrose metabolism";"Glycogen synthesis" PCG65758.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" PCG73277.1 11 Reactome: R-HSA-3299685;Reactome: R-HSA-111463;Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-111458 "Detoxification of Reactive Oxygen Species";"SMAC (DIABLO) binds to IAPs";"Mitochondrial protein import";"Respiratory electron transport";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome" PCG78092.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG78193.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG80383.1 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism" PCG79303.1 8 KEGG: 00950+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5394;MetaCyc: PWY-6133;MetaCyc: PWY-5049;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2 "Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Rosmarinic acid biosynthesis II";"Catecholamine biosynthesis";"Folate biosynthesis";"Tyrosine metabolism" PCG72352.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG63030.1 4 MetaCyc: PWY-7805;Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation" PCG64281.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" PCG64821.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" PCG78019.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG80993.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" PCG68106.1 30 Reactome: R-HSA-9614399;Reactome: R-HSA-111447;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-69656;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-9634638;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-69202;Reactome: R-HSA-211163;Reactome: R-HSA-5674400;Reactome: R-HSA-1358803;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-198323;Reactome: R-HSA-5628897;Reactome: R-HSA-392451;Reactome: R-HSA-389513;Reactome: R-HSA-8876198;Reactome: R-HSA-6804759;Reactome: R-HSA-199418;KEGG: 04150+2.7.11.1 "Regulation of localization of FOXO transcription factors";"Activation of BAD and translocation to mitochondria";"Human cytomegalovirus infection";"Regulation of PTEN stability and activity";"Cyclin A:Cdk2-associated events at S phase entry";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the nucleus";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Human papillomavirus infection";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of TP53 Activity through Acetylation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Cyclin E associated events during G1/S transition";"AKT-mediated inactivation of FOXO1A";"Constitutive Signaling by AKT1 E17K in Cancer";"Downregulation of ERBB2:ERBB3 signaling";"Relaxin signaling pathway";"RUNX2 regulates genes involved in cell migration";"AKT phosphorylates targets in the cytosol";"TP53 Regulates Metabolic Genes";"G beta:gamma signalling through PI3Kgamma";"CTLA4 inhibitory signaling";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TP53 Activity through Association with Co-factors";"Negative regulation of the PI3K/AKT network";"mTOR signaling pathway" PCG67602.1 44 Reactome: R-HSA-982772;Reactome: R-HSA-9634638;Reactome: R-HSA-9649948;Reactome: R-HSA-445144;Reactome: R-HSA-5668599;Reactome: R-HSA-2559585;Reactome: R-HSA-9627069;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-444257;Reactome: R-HSA-5675221;Reactome: R-HSA-2871796;Reactome: R-HSA-879415;Reactome: R-HSA-8939211;Reactome: R-HSA-6802955;Reactome: R-HSA-170968;Reactome: R-HSA-6802948;Reactome: R-HSA-5663213;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5673001;Reactome: R-HSA-74749;Reactome: R-HSA-6802946;Reactome: R-HSA-2559582;Reactome: R-HSA-450341;Reactome: R-HSA-162658;Reactome: R-HSA-112409;Reactome: R-HSA-6811558;Reactome: R-HSA-5654732;Reactome: R-HSA-6802952;Reactome: R-HSA-3371453;Reactome: R-HSA-1295596;Reactome: R-HSA-198753;Reactome: R-HSA-375165;Reactome: R-HSA-9635465;Reactome: R-HSA-5654733;Reactome: R-HSA-5674499;Reactome: R-HSA-8940973;Reactome: R-HSA-202670;Reactome: R-HSA-456926;Reactome: R-HSA-2559580;Reactome: R-HSA-5654727;Reactome: R-HSA-881907;Reactome: R-HSA-2029482;Reactome: R-HSA-5654726 "Growth hormone receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling downstream of RAS mutants";"Signal transduction by L1";"RHO GTPases Activate NADPH Oxidases";"Oncogene Induced Senescence";"Regulation of the apoptosome activity";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"RSK activation";"Negative regulation of MAPK pathway";"FCERI mediated MAPK activation";"Advanced glycosylation endproduct receptor signaling";"ESR-mediated signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Frs2-mediated activation";"Signaling by high-kinase activity BRAF mutants";"RHO GTPases Activate WASPs and WAVEs";"mTOR signaling pathway";"RAF/MAP kinase cascade";"Signal attenuation";"Signaling by moderate kinase activity BRAF mutants";"Senescence-Associated Secretory Phenotype (SASP)";"Activation of the AP-1 family of transcription factors";"Golgi Cisternae Pericentriolar Stack Reorganization";"RAF-independent MAPK1/3 activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of FGFR3 signaling";"Signaling by BRAF and RAF fusions";"Regulation of HSF1-mediated heat shock response";"Spry regulation of FGF signaling";"ERK/MAPK targets";"NCAM signaling for neurite out-growth";"Suppression of apoptosis";"Negative regulation of FGFR4 signaling";"Negative feedback regulation of MAPK pathway";"RUNX2 regulates osteoblast differentiation";"ERKs are inactivated";"Thrombin signalling through proteinase activated receptors (PARs)";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR2 signaling";"Gastrin-CREB signalling pathway via PKC and MAPK";"Regulation of actin dynamics for phagocytic cup formation";"Negative regulation of FGFR1 signaling" PCG71356.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" PCG74442.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" PCG68973.1 4 KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Metabolism of polyamines" PCG67189.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" PCG73706.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" PCG65265.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399 "SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy" PCG67530.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" PCG74054.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" PCG72578.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG75125.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG75942.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-203927 "Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis" PCG70959.1 4 KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" PCG78933.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" PCG63293.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" PCG79323.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" PCG75165.1 8 KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" PCG73931.1 7 Reactome: R-HSA-2160456;MetaCyc: PWY-6134;MetaCyc: PWY-7158;KEGG: 00400+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1 "Phenylketonuria";"L-tyrosine biosynthesis IV";"L-phenylalanine degradation V";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism" PCG76354.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" PCG69716.1 5 Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-983231 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production" PCG72007.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" PCG72790.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" PCG72649.1 13 MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I" PCG77413.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" PCG77291.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG66750.1 12 Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane" PCG69066.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135 "Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER" PCG77480.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" PCG70067.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG64149.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG64099.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG64567.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG70961.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" PCG78294.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" PCG72011.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" PCG70005.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG78113.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG78945.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG68281.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" PCG76462.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-110381;Reactome: R-HSA-5649702 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" PCG67653.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" PCG69276.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG76079.1 15 Reactome: R-HSA-674695;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167200 "RNA Polymerase II Pre-transcription Events";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat" PCG81044.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG73049.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" PCG80562.1 4 Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-7546;MetaCyc: PWY-6482 "Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)" PCG78466.1 4 KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261 "Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" PCG76580.1 1 Reactome: R-HSA-400253 "Circadian Clock" PCG73608.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" PCG76866.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" PCG63551.1 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891 "Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)" PCG76472.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane" PCG64216.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis" PCG73922.1 3 Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801 "Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)" PCG76325.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" PCG66797.1 4 Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-77075 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE" PCG75519.1 4 MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" PCG66676.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG71400.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG71421.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" PCG68435.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" PCG76961.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" PCG66929.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG71770.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG80175.1 1 Reactome: R-HSA-3295583 "TRP channels" PCG79848.1 14 MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-6453;Reactome: R-HSA-4419969;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4 "Anandamide biosynthesis II";"Sphingolipid metabolism";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Depolymerisation of the Nuclear Lamina";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"Ether lipid metabolism" PCG73604.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" PCG64703.1 4 Reactome: R-HSA-446199;Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108 "Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis" PCG67825.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG75609.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" PCG66240.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" PCG80173.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG63318.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" PCG66443.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-170660 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (i) signalling events";"Adenylate cyclase activating pathway" PCG67823.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" PCG66628.1 8 Reactome: R-HSA-2467813;Reactome: R-HSA-6783310;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-606279 "Separation of Sister Chromatids";"Fanconi Anemia Pathway";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere" PCG78545.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation" PCG81026.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-8951430 "Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling" PCG63324.1 5 Reactome: R-HSA-5610780;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783 "Degradation of GLI1 by the proteasome";"Hedgehog 'off' state";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome" PCG74377.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" PCG67129.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" PCG70639.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG74598.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG74835.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG79831.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" PCG73596.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II" PCG67105.1 11 KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-381;MetaCyc: PWY-6963;MetaCyc: PWY-6549;MetaCyc: PWY-6964;KEGG: 00630+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675 "Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Glyoxylate and dicarboxylate metabolism";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)" PCG75080.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174084 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C" PCG69534.1 4 KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260 "Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" PCG62683.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG63579.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" PCG63252.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" PCG63111.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG79620.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG80730.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" PCG72638.1 3 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" PCG78966.1 31 MetaCyc: PWY-7388;MetaCyc: PWY-5142;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWYG-321;MetaCyc: PWY-7663;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-5973;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7746;MetaCyc: PWY-5147 "Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"";"Gondoate biosynthesis (anaerobic)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)" PCG80508.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" PCG74900.1 25 Reactome: R-HSA-8940973;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-8941326;Reactome: R-HSA-8949275;Reactome: R-HSA-8941858;Reactome: R-HSA-8939243;Reactome: R-HSA-8878166;Reactome: R-HSA-8931987;Reactome: R-HSA-8941284;Reactome: R-HSA-8939256;Reactome: R-HSA-8935964;Reactome: R-HSA-8951911;Reactome: R-HSA-8941332;Reactome: R-HSA-8941333;Reactome: R-HSA-8939247;Reactome: R-HSA-8939246;Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8939236;Reactome: R-HSA-8939242;Reactome: R-HSA-9616222;Reactome: R-HSA-8939245;Reactome: R-HSA-8934593;Reactome: R-HSA-8877330 "RUNX2 regulates osteoblast differentiation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"RUNX2 regulates bone development";"RUNX3 Regulates Immune Response and Cell Migration";"Regulation of RUNX3 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional regulation by RUNX2";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX1 regulates expression of components of tight junctions";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX1 Expression and Activity";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)" PCG65967.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" PCG77782.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG71648.1 2 KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5 "Fructose and mannose metabolism";"Pentose and glucuronate interconversions" PCG78458.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-9615017 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" PCG66602.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG68552.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" PCG63470.1 13 Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-139853;Reactome: R-HSA-5607763 "DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Ion homeostasis";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation" PCG77485.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG66629.1 8 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6783310;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Fanconi Anemia Pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation" PCG76015.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-416476;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"G alpha (q) signalling events";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism" PCG67214.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408 "snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism" PCG69633.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG70768.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG76229.1 8 Reactome: R-HSA-6804115;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" PCG70700.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" PCG79987.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG66003.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" PCG74149.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG80422.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG80602.1 4 MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268 "Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" PCG81120.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels" PCG79121.1 19 Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484 "VLDL clearance";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Chylomicron remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"VLDL assembly";"LDL remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors" PCG74003.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG75505.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" PCG64883.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" PCG68928.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG74522.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" PCG73816.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG76583.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation" PCG77388.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG64704.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" PCG79513.1 14 MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453 "Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis" PCG63714.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" PCG73935.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" PCG67479.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" PCG71498.1 3 MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3 "Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism" PCG79860.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG77979.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" PCG72871.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG65670.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG68733.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429 "Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" PCG78965.1 31 MetaCyc: PWY-8047;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-6519;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-7388;MetaCyc: PWY-5142;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-6113;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-7746;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-7723;MetaCyc: PWY-5973;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989 "Bryostatin biosynthesis";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"";"Gondoate biosynthesis (anaerobic)";"Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Bacterial bioluminescence";"Cis-vaccenate biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)" PCG75451.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG78884.1 18 Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG75069.1 13 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 04926+2.7.11.1;Reactome: R-HSA-9649948 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Relaxin signaling pathway";"Signaling downstream of RAS mutants" PCG62537.1 15 Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5689896;Reactome: R-HSA-195253;Reactome: R-HSA-111465;Reactome: R-HSA-5358751 "S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex";"Apoptotic cleavage of cellular proteins";"S45 mutants of beta-catenin aren't phosphorylated" PCG81116.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels" PCG80507.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" PCG80850.1 4 Reactome: R-HSA-2129379;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170 "Molecules associated with elastic fibres";"Integrin cell surface interactions";"ECM proteoglycans";"Syndecan interactions" PCG78753.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG78289.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" PCG78127.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination" PCG64946.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG71408.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" PCG65129.1 4 KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" PCG68738.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" PCG69216.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-400253 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock" PCG73763.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG62641.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" PCG77065.1 6 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" PCG76436.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events" PCG62436.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG80075.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" PCG63238.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" PCG63307.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693568 "Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates" PCG77981.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" PCG71649.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG79089.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG70155.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG74837.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG63892.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG71383.1 4 MetaCyc: PWY-6309;MetaCyc: PWY-5651;Reactome: R-HSA-71240;KEGG: 00380+3.7.1.3 "L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan catabolism";"Tryptophan metabolism" PCG80449.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" PCG74689.1 7 MetaCyc: PWY-7791;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7790 "UMP biosynthesis III";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"UMP biosynthesis I";"UMP biosynthesis II" PCG67663.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" PCG71144.1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" PCG80085.1 7 MetaCyc: PWY-4984;KEGG: 00330+3.5.3.1;MetaCyc: PWY-46;MetaCyc: PWY-6922;MetaCyc: PWY-31;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1 "Urea cycle";"Arginine and proline metabolism";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Canavanine degradation";"Urea cycle";"Arginine biosynthesis" PCG68925.1 7 MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" PCG72745.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" PCG72420.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG70995.1 18 Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-3108214;Reactome: R-HSA-5693554;MetaCyc: PWY-7511;Reactome: R-HSA-5693616;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-1221632 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Protein ubiquitination";"Presynaptic phase of homologous DNA pairing and strand exchange";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Meiotic synapsis" PCG67201.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II" PCG66484.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" PCG70916.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG75281.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" PCG68051.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" PCG63648.1 5 KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22 "Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism";"Galactose metabolism" PCG80521.1 4 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;Reactome: R-HSA-383280 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Nuclear Receptor transcription pathway" PCG71399.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG62582.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG68102.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG64058.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG67099.1 3 KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" PCG80792.1 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-7328 "Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" PCG78385.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG72508.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" PCG69924.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" PCG65491.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG69498.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG79726.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"NRAGE signals death through JNK";"Rho GTPase cycle" PCG76911.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" PCG62886.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" PCG74415.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" PCG63124.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" PCG78322.1 13 MetaCyc: PWY-2261;MetaCyc: PWY-6370;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-196836;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112 "Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification" PCG67098.1 3 Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" PCG67328.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG68126.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG79242.1 11 KEGG: 00250+2.1.3.2;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5686;KEGG: 00240+2.1.3.2;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7400;Reactome: R-HSA-500753;MetaCyc: PWY-7790;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3 "Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine biosynthesis";"UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism" PCG65114.1 5 Reactome: R-HSA-9609523;Reactome: R-HSA-5694530;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-204005 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Cargo concentration in the ER";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPII-mediated vesicle transport" PCG75124.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG66248.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG76285.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG70246.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG73079.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" PCG72634.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG80971.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" PCG77287.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" PCG69675.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG66146.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" PCG64858.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" PCG70622.1 4 KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" PCG72922.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" PCG76582.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG68949.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" PCG75166.1 8 Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Signaling by Hippo";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" PCG73086.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG65375.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" PCG79378.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" PCG72370.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG76478.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG69838.1 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" PCG77421.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" PCG68737.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-264642 "Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" PCG72083.1 2 Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis" PCG71035.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" PCG78319.1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962 "G1/S-Specific Transcription";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex" PCG78362.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG65983.1 17 MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7221;MetaCyc: PWY-7205 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation" PCG76523.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" PCG81032.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4641265 "RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes" PCG70548.1 5 Reactome: R-HSA-5205685;Reactome: R-HSA-209543;Reactome: R-HSA-209560;Reactome: R-HSA-205043;Reactome: R-HSA-9020702 "Pink/Parkin Mediated Mitophagy";"p75NTR recruits signalling complexes";"NF-kB is activated and signals survival";"NRIF signals cell death from the nucleus";"Interleukin-1 signaling" PCG73880.1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation" PCG70803.1 6 Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" PCG63339.1 6 KEGG: 00562+3.1.3.64+3.1.3.95;KEGG: 04070+3.1.3.64+3.1.3.95;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;MetaCyc: PWY-6367;MetaCyc: PWY-6580 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)" PCG66651.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" PCG70075.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG76925.1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"FCERI mediated NF-kB activation";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Degradation of DVL" PCG62753.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG80601.1 4 MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway";"Glutathione metabolism";"Entner-Doudoroff pathway I" PCG71192.1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661 "Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation" PCG77613.1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" PCG79915.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG77337.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG70910.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" PCG63014.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG75075.1 8 MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P" PCG75753.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG73245.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" PCG72115.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG80381.1 3 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" PCG74890.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" PCG64120.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" PCG63763.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG74148.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" PCG72423.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex" PCG76288.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG78843.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG72652.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG79728.1 9 Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-2871809 "VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"NRAGE signals death through JNK";"Rho GTPase cycle";"GPVI-mediated activation cascade";"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization" PCG72723.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" PCG72044.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" PCG69193.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway" PCG77016.1 13 Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52 "CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Other glycan degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis" PCG73566.1 33 Reactome: R-HSA-141444;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"snRNP Assembly";"Separation of Sister Chromatids";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins" PCG75161.1 8 KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" PCG74007.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis" PCG64831.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG72818.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG79654.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" PCG80529.1 11 Reactome: R-HSA-74259;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-6999;MetaCyc: PWY-6596;Reactome: R-HSA-8851680;MetaCyc: PWY-6538;MetaCyc: PWY-5497 "Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Theophylline degradation";"Adenosine nucleotides degradation I";"Butyrophilin (BTN) family interactions";"Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)" PCG79809.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG67063.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" PCG77935.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG72928.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG64881.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" PCG67029.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208 "Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling" PCG65454.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG63287.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" PCG80063.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" PCG76341.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" PCG71207.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" PCG71835.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG68333.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" PCG78159.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG77907.1 5 MetaCyc: PWY-5981;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)" PCG68245.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1" PCG64868.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG63655.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" PCG70448.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" PCG79770.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295 "Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Glycosphingolipid metabolism";"MHC class II antigen presentation" PCG76956.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" PCG69908.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" PCG63364.1 14 KEGG: 00680+2.1.2.1;KEGG: 00670+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-181;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;Reactome: R-HSA-196757;MetaCyc: PWY-3841 "Methane metabolism";"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine betaine degradation I";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Photorespiration ";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Metabolism of folate and pterines";"Folate transformations II (plants)" PCG78752.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG78867.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" PCG74967.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" PCG79235.1 27 Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-180910 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"snRNP Assembly";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs" PCG63141.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG65782.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" PCG71060.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG68030.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" PCG71061.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG80901.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" PCG74153.1 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" PCG66829.1 20 MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism" PCG63155.1 3 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" PCG62458.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" PCG62986.1 57 Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-4608870 "Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Asymmetric localization of PCP proteins" PCG66324.1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" PCG80133.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" PCG79500.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG81073.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG71992.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" PCG71082.1 4 KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism" PCG74509.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases" PCG65115.1 13 MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7198;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates" PCG81110.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG67959.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG64921.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG79954.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG78961.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG78773.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" PCG76295.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" PCG73915.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG73341.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG63486.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG78732.1 19 MetaCyc: PWY-5392;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622 "Reductive TCA cycle II";"Pyruvate metabolism";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)" PCG80723.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" PCG76404.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG79643.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG74133.1 8 KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1 "Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" PCG80902.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" PCG69263.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG70531.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" PCG74841.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG74707.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG71002.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG80554.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG68989.1 9 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-69017;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" PCG74893.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG79746.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6804756 "Receptor Mediated Mitophagy";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"WNT mediated activation of DVL";"Regulation of TP53 Activity through Phosphorylation" PCG74584.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG77213.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276 "Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint" PCG63595.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG71428.1 4 Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807062;MetaCyc: PWY-8026 "Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)" PCG66154.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG80555.1 8 MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis" PCG71720.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG65553.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" PCG77187.1 9 KEGG: 05165+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"AKT phosphorylates targets in the cytosol";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway" PCG78783.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" PCG65520.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695 "Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation" PCG67124.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" PCG73276.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG66080.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" PCG79410.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" PCG69510.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway" PCG77749.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids" PCG78626.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Gap junction degradation" PCG66087.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG73278.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG76050.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" PCG66221.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" PCG69648.1 8 MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;Reactome: R-HSA-74217;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-6609;Reactome: R-HSA-6798695 "Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Purine salvage";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Adenine and adenosine salvage III";"Neutrophil degranulation" PCG77442.1 2 KEGG: 00760+2.7.1.173+2.7.1.22;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" PCG75521.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" PCG67991.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG73927.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" PCG65563.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" PCG62997.1 57 Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-349425 "Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ub-specific processing proteases";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1" PCG64757.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" PCG67284.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" PCG73679.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" PCG68412.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG79687.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" PCG78373.1 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" PCG64492.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG70298.1 56 Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5362768 "APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ub-specific processing proteases";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" PCG74020.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" PCG67600.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" PCG78940.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG77986.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" PCG79598.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" PCG71985.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG63570.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG67715.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG64377.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG73795.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG69947.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG68686.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG70933.1 7 Reactome: R-HSA-73817;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219 "Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" PCG69113.1 18 KEGG: 00350+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;MetaCyc: PWY-7383;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00401+2.6.1.1 "Tyrosine metabolism";"Sulfolactate degradation III";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Novobiocin biosynthesis" PCG75615.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG78818.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG74113.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" PCG64102.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG68387.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" PCG68746.1 6 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network" PCG72966.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG77166.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" PCG63553.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG74819.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" PCG72575.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG70800.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" PCG79589.1 17 MetaCyc: PWY-7198;MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7221;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I" PCG63423.1 9 KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00270+2.6.1.5 "Phenylalanine metabolism";"Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Cysteine and methionine metabolism" PCG65232.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" PCG78543.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1445148;Reactome: R-HSA-1660499 "Neutrophil degranulation";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane" PCG71381.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG63011.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG70313.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5362768;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050 "Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Ub-specific processing proteases";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" PCG75343.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" PCG76890.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG75346.1 3 KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041 "Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle" PCG74029.1 6 KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2 "Oxidative phosphorylation";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import";"Photosynthesis" PCG69715.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" PCG68509.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" PCG68247.1 8 KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Photosynthesis";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ATP biosynthesis";"Oxidative phosphorylation";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes" PCG77723.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG71024.1 57 Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562 "Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)" PCG72227.1 12 MetaCyc: PWY-7118;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1 "Chitin degradation to ethanol";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes" PCG75535.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG74984.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG75855.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG68038.1 13 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-389357 "Macroautophagy";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling" PCG74569.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" PCG67581.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG71969.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" PCG77382.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation" PCG77899.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG77062.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG71522.1 3 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism" PCG73506.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" PCG68403.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG65004.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" PCG79255.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol" PCG64705.1 27 Reactome: R-HSA-111367;Reactome: R-HSA-159231;Reactome: R-HSA-6803529;Reactome: R-HSA-975956;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-77588;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-167242;Reactome: R-HSA-72187;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-77595;Reactome: R-HSA-113418 "SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"FGFR2 alternative splicing";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA 3'-end processing";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Intronless Pre-mRNAs";"Formation of the Early Elongation Complex" PCG64836.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG67611.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" PCG70156.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG62510.1 32 Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167290;Reactome: R-HSA-167161;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-6803529 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of HIV elongation";"HIV Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"FGFR2 alternative splicing" PCG66483.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" PCG64878.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" PCG69565.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" PCG78851.1 6 MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism" PCG80211.1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" PCG72752.1 15 Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-2559586 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"DNA Damage/Telomere Stress Induced Senescence" PCG74252.1 3 KEGG: 00511+3.2.1.45;KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid metabolism" PCG69699.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG73249.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" PCG64972.1 11 Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation" PCG78762.1 1 Reactome: R-HSA-71064 "Lysine catabolism" PCG73403.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG65003.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" PCG66432.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" PCG65886.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" PCG74582.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG65401.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" PCG66253.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG77103.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" PCG63490.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy" PCG77839.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Regulation of TP53 Activity through Phosphorylation" PCG72612.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" PCG79011.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" PCG67461.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" PCG74844.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG71333.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" PCG77765.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" PCG66079.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" PCG80603.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG75373.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis" PCG77936.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG64563.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG78020.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG64451.1 3 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;KEGG: 00480+3.4.11.2 "VLDL assembly";"Chylomicron assembly";"Glutathione metabolism" PCG78236.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" PCG65311.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase" PCG80700.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones" PCG74725.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG71339.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" PCG77286.1 5 MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757 "Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Folate biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines" PCG80469.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG79515.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis" PCG73997.1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" PCG78021.1 7 MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" PCG80838.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG73701.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785 "Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome" PCG75735.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1 "Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" PCG70090.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" PCG69594.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG69974.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG80356.1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG76678.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" PCG78936.1 33 Reactome: R-HSA-141444;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-168271 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"snRNP Assembly";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus" PCG77018.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG78792.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG66621.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" PCG69880.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG76960.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" PCG76962.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" PCG70547.1 5 Reactome: R-HSA-9020702;Reactome: R-HSA-209543;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-209560 "Interleukin-1 signaling";"p75NTR recruits signalling complexes";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"NF-kB is activated and signals survival" PCG70948.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" PCG68478.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" PCG70125.1 1 Reactome: R-HSA-8964038 "LDL clearance" PCG63642.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" PCG63353.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" PCG76447.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG65227.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG70699.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" PCG66794.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135 "Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER" PCG65606.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" PCG76344.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" PCG78541.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG76197.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" PCG67289.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1442490;Reactome: R-HSA-6798695;Reactome: R-HSA-2022090;Reactome: R-HSA-1679131 "MHC class II antigen presentation";"Collagen degradation";"Neutrophil degranulation";"Assembly of collagen fibrils and other multimeric structures";"Trafficking and processing of endosomal TLR" PCG78529.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG77849.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG80857.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG76667.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway" PCG71401.1 14 Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-113418 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex" PCG71846.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690 "SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events" PCG72931.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" PCG70996.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG72441.1 1 Reactome: R-HSA-8876725 "Protein methylation" PCG79081.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG74261.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG69204.1 25 Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-416482;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-381771;Reactome: R-HSA-9009391 "Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G alpha (12/13) signalling events";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Extra-nuclear estrogen signaling" PCG77105.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" PCG66554.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" PCG65171.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG72494.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" PCG67217.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" PCG77330.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG78125.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination" PCG73551.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG74482.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG80990.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" PCG70752.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" PCG72340.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" PCG79501.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" PCG65264.1 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710 "Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy" PCG71589.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" PCG76199.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG70431.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" PCG63465.1 5 Reactome: R-HSA-211976;Reactome: R-HSA-8937144;Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-211945 "Endogenous sterols";"Aryl hydrocarbon receptor signalling";"PPARA activates gene expression";"Xenobiotics";"Phase I - Functionalization of compounds" PCG77171.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" PCG70805.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG63741.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG70645.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG66744.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway" PCG72622.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" PCG64922.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG76171.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" PCG66227.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" PCG79738.1 7 Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381070 "ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones" PCG66029.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" PCG66175.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG67406.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" PCG65958.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG77221.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG64684.1 22 KEGG: 00500+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-5514;KEGG: 00010+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-6992;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-621;MetaCyc: PWY-6981;Reactome: R-HSA-6798695;MetaCyc: PWY-5384;Reactome: R-HSA-70263;MetaCyc: PWY-5659;MetaCyc: PWY-8013;MetaCyc: PWY-7385;KEGG: 00030+5.3.1.9;MetaCyc: PWY-622;MetaCyc: PWY-5054;Reactome: R-HSA-5628897;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9 "Starch and sucrose metabolism";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis / Gluconeogenesis";"Sucrose degradation II (sucrose synthase)";"1,5-anhydrofructose degradation";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Sucrose degradation III (sucrose invertase)";"Chitin biosynthesis";"Neutrophil degranulation";"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Starch biosynthesis";"D-sorbitol biosynthesis I";"TP53 Regulates Metabolic Genes";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism" PCG78673.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG71315.1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" PCG69571.1 1 Reactome: R-HSA-912446 "Meiotic recombination" PCG70902.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" PCG65062.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG78393.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG77140.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade" PCG66000.1 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" PCG74454.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway" PCG80300.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG75339.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" PCG78919.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG72231.1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239 "Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1" PCG72313.1 9 Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates" PCG71636.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" PCG71745.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" PCG65208.1 3 Reactome: R-HSA-5660489;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781 "MTF1 activates gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression" PCG76922.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" PCG63405.1 13 MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1 "Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis" PCG78623.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" PCG72148.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG79913.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135 "Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Dual incision in TC-NER" PCG64796.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG75543.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" PCG65023.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification" PCG76076.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" PCG76998.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693579 "Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange" PCG76532.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" PCG70962.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG76503.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" PCG73719.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG63864.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG77001.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG69550.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG67635.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG79112.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" PCG73710.1 22 MetaCyc: PWY-6958;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7728;MetaCyc: PWY-7724;MetaCyc: PWY-5353;MetaCyc: PWY-7049;MetaCyc: PWY-7592;MetaCyc: PWY-7606;MetaCyc: PWY-7727;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-7725 "Icosapentaenoate biosynthesis I (lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)" PCG79131.1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167238 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation" PCG63666.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" PCG79411.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" PCG76292.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG71784.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" PCG65435.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972 "(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)" PCG78228.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" PCG77712.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" PCG64510.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" PCG75740.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG63199.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG80323.1 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" PCG73434.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-164378 "Adenylate cyclase activating pathway";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling" PCG62571.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG76708.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG65843.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" PCG76343.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" PCG66454.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" PCG65105.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" PCG64101.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG63527.1 6 KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6123;MetaCyc: PWY-6124;Reactome: R-HSA-73817;MetaCyc: PWY-7234 "Purine metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III" PCG71098.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" PCG78422.1 3 KEGG: 00510+2.4.1.267;Reactome: R-HSA-446193;Reactome: R-HSA-4724289 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)" PCG73588.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching" PCG70565.1 12 MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7233;MetaCyc: PWY-5856 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" PCG78367.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-5140745 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" PCG74891.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" PCG71637.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" PCG62427.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG77980.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" PCG65966.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" PCG69599.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG63680.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG80676.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG65559.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis" PCG78844.1 5 Reactome: R-HSA-171007;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097 "p38MAPK events";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway" PCG69432.1 27 Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453 "SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response" PCG71331.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" PCG67272.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "Release of Hh-Np from the secreting cell";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" PCG70318.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" PCG73639.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG71733.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" PCG76475.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG65504.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG76581.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG73087.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG69110.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG68615.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" PCG80192.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG81103.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" PCG64395.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG79384.1 7 Reactome: R-HSA-201681;Reactome: R-HSA-201688;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-5368598;Reactome: R-HSA-4086400;Reactome: R-HSA-5663220 "TCF dependent signaling in response to WNT";"WNT mediated activation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"PCP/CE pathway";"RHO GTPases Activate Formins" PCG71596.1 17 Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-113418 "HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex" PCG72705.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" PCG67889.1 6 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" PCG68914.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG79920.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5689880 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases" PCG74895.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG67141.1 29 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-69541;Reactome: R-HSA-6804760;Reactome: R-HSA-5685938;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-6803207;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-349425;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;Reactome: R-HSA-5693579;Reactome: R-HSA-6803204;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693565 "Relaxin signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"Stabilization of p53";"Regulation of TP53 Activity through Methylation";"HDR through Single Strand Annealing (SSA)";"mTOR signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Autodegradation of the E3 ubiquitin ligase COP1";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Human papillomavirus infection";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" PCG66047.1 9 MetaCyc: PWY-6147;MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-7442 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis" PCG66310.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1368082 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RORA activates gene expression" PCG67995.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763 "MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction" PCG78194.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" PCG68895.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG72031.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG63333.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG65916.1 24 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239 "Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1" PCG71057.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG74593.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" PCG69123.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" PCG79766.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" PCG78190.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG79277.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" PCG73028.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" PCG78854.1 6 MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13 "L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" PCG78259.1 29 Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-112382 "Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex" PCG71799.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG77842.1 13 Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-216083 "Collagen degradation";"Anchoring fibril formation";"NCAM1 interactions";"ECM proteoglycans";"Extracellular matrix organization";"Collagen chain trimerization";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions" PCG78600.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" PCG78047.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG73142.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" PCG73124.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" PCG67655.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" PCG72996.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG68409.1 11 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane" PCG73211.1 5 Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)" PCG74743.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG66737.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG68947.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" PCG69485.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" PCG64681.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-5628897 "RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes" PCG69737.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG70416.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-6798695;Reactome: R-HSA-6785631 "RHO GTPases Activate Formins";"Neutrophil degranulation";"ERBB2 Regulates Cell Motility" PCG80881.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" PCG70029.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837 "UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"FCERI mediated NF-kB activation" PCG65893.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG65471.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG71953.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG66308.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" PCG64976.1 1 Reactome: R-HSA-5676934 "Protein repair" PCG73563.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" PCG68169.1 6 MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3 "Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophospholipid metabolism" PCG77384.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" PCG70657.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG65883.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching" PCG72967.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG67287.1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1442490 "Trafficking and processing of endosomal TLR";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation";"Collagen degradation" PCG66347.1 4 Reactome: R-HSA-8963889;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829 "Assembly of active LPL and LIPC lipase complexes";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" PCG64941.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG76047.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG79858.1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" PCG80953.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG78537.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG72400.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" PCG65362.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG79412.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG81027.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"RUNX3 regulates WNT signaling" PCG75562.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" PCG65795.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" PCG64798.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG80482.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" PCG69148.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578998 "Glutathione synthesis and recycling";"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)" PCG63651.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" PCG64083.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168 "Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)" PCG66318.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-918233 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway" PCG71427.1 4 Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047;MetaCyc: PWY-8026 "Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol";"Sterol biosynthesis (methylotrophs)" PCG64424.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" PCG76127.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG80904.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" PCG63530.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" PCG75741.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" PCG64422.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" PCG71412.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700 "Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus" PCG64125.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" PCG76959.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" PCG77833.1 13 Reactome: R-HSA-1650814;Reactome: R-HSA-3000157;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-2022090;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1474244;Reactome: R-HSA-3000178;Reactome: R-HSA-419037;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Laminin interactions";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Assembly of collagen fibrils and other multimeric structures";"Signaling by PDGF";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Extracellular matrix organization";"ECM proteoglycans";"NCAM1 interactions";"Collagen degradation";"Anchoring fibril formation" PCG71901.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" PCG66237.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG71171.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG62520.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG70124.1 1 Reactome: R-HSA-8964038 "LDL clearance" PCG64340.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" PCG75782.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" PCG75245.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG67143.1 15 MetaCyc: PWY-5723;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-7218;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886 "Rubisco shunt";"Entner-Doudoroff pathway I";"Purine metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)" PCG71209.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" PCG72721.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" PCG68741.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG64661.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG77610.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" PCG72366.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" PCG68743.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" PCG76569.1 1 Reactome: R-HSA-419771 "Opsins" PCG65262.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" PCG73240.1 3 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205;Reactome: R-HSA-6798163 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Choline catabolism" PCG79742.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG70134.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" PCG72733.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" PCG67599.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG72042.1 6 KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia" PCG62669.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG66934.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG68154.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" PCG67978.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" PCG69644.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis" PCG75739.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" PCG72368.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" PCG64296.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516 "Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation" PCG74761.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" PCG76716.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" PCG75243.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG68391.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG68418.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" PCG75489.1 14 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-2022377;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Metabolism of Angiotensinogen to Angiotensins";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG72240.1 4 KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis" PCG70436.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-113418 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex" PCG74306.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism" PCG72038.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" PCG74361.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG74510.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG70440.1 13 MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7721;MetaCyc: PWY-7410 "Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Ipsdienol biosynthesis" PCG65808.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68689 "Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex" PCG79741.1 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" PCG77920.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" PCG78861.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" PCG71173.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG62512.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560801 "Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B3GAT3 causes JDSSDHD" PCG73877.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG66663.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG68647.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG75158.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway" PCG66171.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" PCG70465.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG75441.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" PCG77015.1 13 KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis" PCG73949.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG65823.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" PCG68744.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" PCG68899.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG63144.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG67865.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG78131.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG76289.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" PCG76155.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" PCG66957.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" PCG65061.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG78185.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG63001.1 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4 "Ether lipid metabolism";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Arachidonic acid metabolism" PCG72493.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" PCG74636.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG73338.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952 "Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions" PCG80120.1 26 Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Attenuation phase";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling" PCG74037.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG78796.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway" PCG72112.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG70872.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" PCG80897.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG77871.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG79440.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" PCG78014.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG73928.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" PCG81043.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG75120.1 4 Reactome: R-HSA-947581;MetaCyc: PWY-7887;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12 "Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" PCG80064.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG66619.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" PCG80112.1 26 Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-918233;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568 "Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Attenuation phase" PCG75407.1 1 Reactome: R-HSA-419771 "Opsins" PCG76265.1 8 Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-432720 "Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis" PCG79061.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG65831.1 2 Reactome: R-HSA-5687128;KEGG: 04150+2.7.11.24 "MAPK6/MAPK4 signaling";"mTOR signaling pathway" PCG67258.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG71321.1 5 Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948 "RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants" PCG76920.1 4 KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" PCG71671.1 6 KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165 "Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)" PCG78436.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG73220.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" PCG80123.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508 "RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Circadian Clock";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription" PCG72229.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG67661.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG76957.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" PCG68614.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" PCG69601.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG72120.1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-202733;Reactome: R-HSA-432142;Reactome: R-HSA-8963901 "Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"VLDL assembly";"LDL remodeling";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Cell surface interactions at the vascular wall";"Platelet sensitization by LDL";"Chylomicron remodeling" PCG64789.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG69848.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG75708.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG78176.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG64727.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG64341.1 18 KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-70268;KEGG: 00280+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00260+1.8.1.4;KEGG: 00020+1.8.1.4;KEGG: 00620+1.8.1.4;Reactome: R-HSA-71403;Reactome: R-HSA-204174;Reactome: R-HSA-6783984;MetaCyc: PWY-5046;Reactome: R-HSA-70895;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-5362517;MetaCyc: PWY-5084 "Propanoate metabolism";"Lysine catabolism";"Pyruvate metabolism";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"Glycine, serine and threonine metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Tryptophan metabolism";"Signaling by Retinoic Acid";"2-oxoglutarate decarboxylation to succinyl-CoA" PCG67380.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG74617.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" PCG72740.1 2 KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201 "Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis" PCG77748.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Separation of Sister Chromatids" PCG62649.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane" PCG77752.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG69344.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" PCG77970.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation" PCG77073.1 19 MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II" PCG63432.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG67145.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG77033.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" PCG72467.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" PCG68595.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG66320.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG62719.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG63781.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" PCG77233.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG66766.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG65708.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)" PCG75496.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" PCG77408.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" PCG78164.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG70660.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" PCG68898.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG68419.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG70103.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" PCG65912.1 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" PCG74851.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG72010.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469 "Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis" PCG77220.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" PCG79740.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" PCG66386.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG75587.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" PCG74420.1 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" PCG70869.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" PCG65804.1 6 MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00270+2.6.1.52 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"Cysteine and methionine metabolism" PCG66319.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" PCG71854.1 17 Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-1834949;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-3270619;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616 "DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Cytosolic sensors of pathogen-associated DNA";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"IRF3-mediated induction of type I IFN";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" PCG64246.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG71743.1 7 MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456 "L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation" PCG76377.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" PCG69139.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG70324.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" PCG74224.1 12 KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801 "Starch and sucrose metabolism";"Stachyose degradation";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)" PCG64760.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" PCG69089.1 1 Reactome: R-HSA-110357 "Displacement of DNA glycosylase by APEX1" PCG65482.1 3 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism" PCG78606.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323 "HSF1-dependent transactivation";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol" PCG67948.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" PCG72327.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" PCG76216.1 57 Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603 "FCERI mediated NF-kB activation";"Neddylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Interleukin-1 signaling";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases" PCG68044.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" PCG67399.1 4 Reactome: R-HSA-373753;Reactome: R-HSA-114608;Reactome: R-HSA-446388;Reactome: R-HSA-3000170 "Nephrin family interactions";"Platelet degranulation";"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components";"Syndecan interactions" PCG75074.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" PCG66692.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8854214 "RAB geranylgeranylation";"TBC/RABGAPs" PCG78953.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG67782.1 14 Reactome: R-HSA-68877;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-168333 "Mitotic Prometaphase";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery" PCG80131.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" PCG75208.1 13 Reactome: R-HSA-110320;Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-532668;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695 "Translesion Synthesis by POLH";"Protein methylation";"Ovarian tumor domain proteases";"HSF1 activation";"Hedgehog ligand biogenesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation" PCG73712.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" PCG65212.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG78812.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" PCG73601.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" PCG69232.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" PCG76483.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG70570.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" PCG72050.1 24 Reactome: R-HSA-418555;Reactome: R-HSA-456926;Reactome: R-HSA-163359;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-8964616;Reactome: R-HSA-418594;Reactome: R-HSA-8964315;Reactome: R-HSA-500657;Reactome: R-HSA-432040;Reactome: R-HSA-420092;Reactome: R-HSA-6814122;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-202040 "G alpha (s) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through CDC42";"G alpha (i) signalling events";"G beta:gamma signalling through BTK";"Presynaptic function of Kainate receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-type ligand receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"G alpha (q) signalling events";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"G-protein activation" PCG77949.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG78013.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" PCG63298.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG68355.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" PCG66683.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG69946.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG73708.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG80121.1 26 Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-9013508;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-2644606 "PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH3 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"Attenuation phase";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"HATs acetylate histones";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" PCG64866.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG80891.1 11 Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-380320 "COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes" PCG80561.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)" PCG65443.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG64919.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" PCG74941.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG62805.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG80548.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG62802.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" PCG62726.1 179 Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-6804756;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-2173796;Reactome: R-HSA-8876493;Reactome: R-HSA-175474;Reactome: R-HSA-5696397;Reactome: R-HSA-983168;Reactome: R-HSA-9013973;Reactome: R-HSA-3785653;Reactome: R-HSA-1358803;Reactome: R-HSA-2173788;Reactome: R-HSA-937041;Reactome: R-HSA-936440;Reactome: R-HSA-5357956;Reactome: R-HSA-72689;Reactome: R-HSA-901032;Reactome: R-HSA-168928;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-9646399;Reactome: R-HSA-912631;Reactome: R-HSA-5678895;Reactome: R-HSA-2173795;Reactome: R-HSA-8939236;Reactome: R-HSA-6782210;Reactome: R-HSA-2979096;Reactome: R-HSA-8863795;Reactome: R-HSA-192823;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-8948747;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-6791226;Reactome: R-HSA-5357905;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-2467813;Reactome: R-HSA-5696394;Reactome: R-HSA-168927;Reactome: R-HSA-977225;Reactome: R-HSA-182971;Reactome: R-HSA-69541;Reactome: R-HSA-174048;Reactome: R-HSA-975144;Reactome: R-HSA-8856828;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-6807004;Reactome: R-HSA-1799339;Reactome: R-HSA-8951664;Reactome: R-HSA-9615710;Reactome: R-HSA-5696395;Reactome: R-HSA-5654733;Reactome: R-HSA-917729;Reactome: R-HSA-6782135;Reactome: R-HSA-5668541;Reactome: R-HSA-9637628;Reactome: R-HSA-975957;Reactome: R-HSA-9033241;Reactome: R-HSA-156827;Reactome: R-HSA-5675482;Reactome: R-HSA-174154;Reactome: R-HSA-201681;Reactome: R-HSA-937072;Reactome: R-HSA-8866652;Reactome: R-HSA-5693565;Reactome: R-HSA-6804757;Reactome: R-HSA-5655862;Reactome: R-HSA-2559585;Reactome: R-HSA-72706;Reactome: R-HSA-174113;Reactome: R-HSA-445989;Reactome: R-HSA-209543;Reactome: R-HSA-5675221;Reactome: R-HSA-8852276;Reactome: R-HSA-110314;Reactome: R-HSA-69231;Reactome: R-HSA-2408557;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-110312;Reactome: R-HSA-2559582;Reactome: R-HSA-2894862;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-532668;Reactome: R-HSA-2122947;Reactome: R-HSA-9633012;Reactome: R-HSA-975110;Reactome: R-HSA-1169408;Reactome: R-HSA-6781823;Reactome: R-HSA-5685942;Reactome: R-HSA-8849469;Reactome: R-HSA-5689896;Reactome: R-HSA-68949;Reactome: R-HSA-1236382;Reactome: R-HSA-2173791;Reactome: R-HSA-5693607;Reactome: R-HSA-8875360;Reactome: R-HSA-2871837;Reactome: R-HSA-9613829;Reactome: R-HSA-8941858;Reactome: R-HSA-110320;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-2559580;Reactome: R-HSA-1253288;Reactome: R-HSA-5654727;Reactome: R-HSA-3322077;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-975956;Reactome: R-HSA-4641263;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-69481;Reactome: R-HSA-9636383;Reactome: R-HSA-4608870;Reactome: R-HSA-917937;Reactome: R-HSA-936964;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-9645460;Reactome: R-HSA-2122948;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-937042;Reactome: R-HSA-400253;Reactome: R-HSA-2644606;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-5654732;Reactome: R-HSA-174490;Reactome: R-HSA-8856825;Reactome: R-HSA-5696400;Reactome: R-HSA-162588;Reactome: R-HSA-9013507;Reactome: R-HSA-156902;Reactome: R-HSA-1295596;Reactome: R-HSA-450408;Reactome: R-HSA-2565942;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-3134975;Reactome: R-HSA-6783310;Reactome: R-HSA-6804760;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-205043;Reactome: R-HSA-450321;Reactome: R-HSA-2691232;Reactome: R-HSA-68827;Reactome: R-HSA-72764;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5689901;Reactome: R-HSA-975163;Reactome: R-HSA-4641257;Reactome: R-HSA-5205685;Reactome: R-HSA-1236974;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-6781827;Reactome: R-HSA-3769402;Reactome: R-HSA-209560;Reactome: R-HSA-8866654;Reactome: R-HSA-2672351;Reactome: R-HSA-5689877 "Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Regulation of TP53 Activity through Phosphorylation";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"InlA-mediated entry of Listeria monocytogenes into host cells";"Assembly Of The HIV Virion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1-dependent activation of IRF3/IRF7";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB2:ERBB3 signaling";"Downregulation of TGF-beta receptor signaling";"IKK complex recruitment mediated by RIP1";"Negative regulators of DDX58/IFIH1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Formation of a pool of free 40S subunits";"ER Quality Control Compartment (ERQC)";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Aggrephagy";"Regulation of signaling by CBL";"Defective CFTR causes cystic fibrosis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Downregulation of ERBB2 signaling";"Viral mRNA Translation";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Regulation of PTEN localization";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of TNFR1 signaling";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Separation of Sister Chromatids";"DNA Damage Recognition in GG-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"Amyloid fiber formation";"EGFR downregulation";"Stabilization of p53";"APC/C:Cdc20 mediated degradation of Cyclin B";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Clathrin-mediated endocytosis";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Negative regulation of MET activity";"SRP-dependent cotranslational protein targeting to membrane";"Neddylation";"Late endosomal microautophagy";"Formation of Incision Complex in GG-NER";"Negative regulation of FGFR4 signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Dual incision in TC-NER";"TNFR2 non-canonical NF-kB pathway";"Modulation by Mtb of host immune system";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peroxisomal protein import";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of necroptotic cell death";"APC/C:Cdc20 mediated degradation of Securin";"TCF dependent signaling in response to WNT";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Degradation";"Translesion synthesis by POLK";"Oncogene Induced Senescence";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SCF-beta-TrCP mediated degradation of Emi1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"p75NTR recruits signalling complexes";"Negative regulation of MAPK pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recognition of DNA damage by PCNA-containing replication complex";"Cyclin D associated events in G1";"Selenocysteine synthesis";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Translesion synthesis by REV1";"Senescence-Associated Secretory Phenotype (SASP)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"NOTCH1 Intracellular Domain Regulates Transcription";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ISG15 antiviral mechanism";"Formation of TC-NER Pre-Incision Complex";"HDR through Homologous Recombination (HRR)";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ovarian tumor domain proteases";"Orc1 removal from chromatin";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Processing of DNA double-strand break ends";"InlB-mediated entry of Listeria monocytogenes into host cell";"FCERI mediated NF-kB activation";"Chaperone Mediated Autophagy";"Regulation of RUNX3 expression and activity";"Translesion Synthesis by POLH";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Oxidative Stress Induced Senescence";"Downregulation of ERBB4 signaling";"Negative regulation of FGFR2 signaling";"Glycogen synthesis";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of FZD by ubiquitination";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"G2/M Checkpoints";"Prevention of phagosomal-lysosomal fusion";"Asymmetric localization of PCP proteins";"Iron uptake and transport";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"Alpha-protein kinase 1 signaling pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"IRAK2 mediated activation of TAK1 complex";"Circadian Clock";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of FGFR3 signaling";"Membrane binding and targetting of GAG proteins";"Cargo recognition for clathrin-mediated endocytosis";"Dual Incision in GG-NER";"Budding and maturation of HIV virion";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Peptide chain elongation";"Spry regulation of FGF signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PLK1 Activity at G2/M Transition";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of innate immune responses to cytosolic DNA";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Methylation";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"NRIF signals cell death from the nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"CDT1 association with the CDC6:ORC:origin complex";"Eukaryotic Translation Termination";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Metalloprotease DUBs";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of AXIN";"Pink/Parkin Mediated Mitophagy";"ER-Phagosome pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Deactivation of the beta-catenin transactivating complex";"NF-kB is activated and signals survival";"E3 ubiquitin ligases ubiquitinate target proteins";"Stimuli-sensing channels";"Josephin domain DUBs" PCG68337.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" PCG68336.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" PCG70184.1 13 MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7182;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7721 "Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Linalool biosynthesis I";"Terpenoid backbone biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis" PCG81058.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" PCG78535.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG73272.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" PCG68309.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG69434.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG71334.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" PCG69492.1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-171306 "Meiotic synapsis";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Packaging Of Telomere Ends" PCG67396.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" PCG79925.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG63256.1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-75815;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880 "Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Ubiquitin-dependent degradation of Cyclin D";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Neddylation";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases" PCG80328.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" PCG70149.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" PCG75649.1 5 Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383 "Gluconeogenesis";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" PCG74729.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" PCG68228.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" PCG74785.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG73179.1 3 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III" PCG62521.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG64470.1 16 Reactome: R-HSA-975155;Reactome: R-HSA-9020702;Reactome: R-HSA-975110;Reactome: R-HSA-6811558;Reactome: R-HSA-5603037;Reactome: R-HSA-166058;Reactome: R-HSA-1257604;Reactome: R-HSA-3134963;Reactome: R-HSA-209543;Reactome: R-HSA-1236974;Reactome: R-HSA-1810476;Reactome: R-HSA-975871;Reactome: R-HSA-5602680;Reactome: R-HSA-5603041;Reactome: R-HSA-5602498;Reactome: R-HSA-975138 "MyD88 dependent cascade initiated on endosome";"Interleukin-1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"p75NTR recruits signalling complexes";"ER-Phagosome pathway";"RIP-mediated NFkB activation via ZBP1";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR5)";"IRAK4 deficiency (TLR2/4)";"MyD88 deficiency (TLR2/4)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" PCG65953.1 6 MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3 "Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"One carbon pool by folate" PCG72430.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG72362.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG68205.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" PCG72836.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG77467.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG73786.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" PCG62933.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis" PCG69707.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" PCG68624.1 17 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG68076.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG73177.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape" PCG74307.1 3 MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" PCG73722.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" PCG68622.1 17 Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG77319.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG74578.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" PCG63518.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" PCG66102.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" PCG74225.1 12 MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801 "Stachyose degradation";"Starch and sucrose metabolism";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)" PCG64902.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" PCG67064.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" PCG76043.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" PCG68854.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" PCG79998.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" PCG68505.1 3 Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4 "Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" PCG70626.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" PCG73431.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG74214.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" PCG72292.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" PCG78580.1 5 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" PCG68870.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" PCG79593.1 18 KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-7115;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-5690 "Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Methane metabolism";"Reductive TCA cycle II";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)" PCG74589.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG71744.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" PCG73607.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG70686.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" PCG78237.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" PCG75442.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" PCG78188.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" PCG71882.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG67812.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" PCG72113.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG68842.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG62947.1 5 KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121 "Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I" PCG74058.1 13 Reactome: R-HSA-416482;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1 "G alpha (12/13) signalling events";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"EPHA-mediated growth cone collapse";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"EPHB-mediated forward signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection" PCG64844.1 7 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism" PCG64544.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" PCG62415.1 9 KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241 "Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" PCG73992.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG73739.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG78467.1 24 Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-3371497 "Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"Recycling pathway of L1";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" PCG77383.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation" PCG80481.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" PCG74801.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" PCG66499.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG78198.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation" PCG70301.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" PCG73762.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG75226.1 20 Reactome: R-HSA-5628897;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "TP53 Regulates Metabolic Genes";"mTOR signaling pathway";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of PTEN gene transcription";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"Thermogenesis";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG68723.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG75614.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG70620.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG66136.1 4 MetaCyc: PWY-7849;MetaCyc: PWY-5691;MetaCyc: PWY-7394;KEGG: 00230+4.1.1.97 "Urate conversion to allantoin III";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Purine metabolism" PCG63355.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" PCG76700.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" PCG71734.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" PCG72616.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" PCG70583.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" PCG76306.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" PCG72875.1 4 Reactome: R-HSA-879415;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "Advanced glycosylation endproduct receptor signaling";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" PCG65141.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-983168 "Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation" PCG69190.1 33 Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-4085377 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"snRNP Assembly";"HCMV Early Events";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins" PCG79581.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960 "BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC" PCG74078.1 6 Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685 "Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species" PCG66703.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG63142.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG77431.1 9 Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"UCH proteinases";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer" PCG64370.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG77934.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG69806.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" PCG64685.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" PCG66442.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway" PCG64826.1 5 Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-350054 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway" PCG76691.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG64085.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" PCG80636.1 10 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722 "Relaxin signaling pathway";"Ub-specific processing proteases";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HATs acetylate histones";"Thermogenesis";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex" PCG65999.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling" PCG71319.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" PCG67003.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" PCG78905.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" PCG69982.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG75230.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" PCG80845.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG74228.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG68834.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG65729.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" PCG73127.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG75246.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-141444 "Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"snRNP Assembly";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG66242.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG63286.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" PCG78096.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)" PCG63525.1 4 Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48 "Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes" PCG66337.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" PCG80949.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG80372.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" PCG63601.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" PCG68320.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG74852.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" PCG62945.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" PCG79240.1 13 MetaCyc: PWY-6807;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206308;KEGG: 00604+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-4085001 "Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Other glycan degradation";"HS-GAG degradation";"Sphingolipid metabolism";"Galactose metabolism";"MPS IV - Morquio syndrome B";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Sialic acid metabolism" PCG79857.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria" PCG66173.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG71280.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" PCG65591.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" PCG79140.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" PCG77645.1 3 MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes" PCG68541.1 6 MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5789 "Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle" PCG75127.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" PCG69102.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" PCG68680.1 22 KEGG: 00010+5.3.1.9;MetaCyc: PWY-5514;MetaCyc: PWY-3801;MetaCyc: PWY-6992;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-621;KEGG: 00500+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-5384;Reactome: R-HSA-70263;MetaCyc: PWY-5659;MetaCyc: PWY-8013;MetaCyc: PWY-6981;Reactome: R-HSA-6798695;MetaCyc: PWY-5054;MetaCyc: PWY-7385;KEGG: 00030+5.3.1.9;MetaCyc: PWY-622;Reactome: R-HSA-5628897;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9 "Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation II (sucrose synthase)";"1,5-anhydrofructose degradation";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Sucrose degradation III (sucrose invertase)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Chitin biosynthesis";"Neutrophil degranulation";"D-sorbitol biosynthesis I";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Starch biosynthesis";"TP53 Regulates Metabolic Genes";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism" PCG64548.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" PCG70889.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG78661.1 8 KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00640+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;MetaCyc: PWY-6901 "Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation" PCG80000.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" PCG76324.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG79735.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG66220.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG75299.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG77709.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG68954.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" PCG78372.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)" PCG76398.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-112043 "Ion homeostasis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"PLC beta mediated events" PCG67207.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-180746 "SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein" PCG64886.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" PCG80884.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript" PCG76270.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" PCG65297.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" PCG75754.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" PCG78085.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" PCG62765.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" PCG75694.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG76704.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG72134.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG63889.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG79997.1 7 KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" PCG67215.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168271 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus" PCG76173.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" PCG69598.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG68284.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" PCG72599.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation" PCG62564.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG71470.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" PCG68040.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" PCG75029.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG63683.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" PCG75988.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7587;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis" PCG70894.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" PCG66058.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-8957275 "LDL remodeling";"VLDL assembly";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"LDL clearance";"VLDL clearance";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Retinoid metabolism and transport";"Post-translational protein phosphorylation" PCG62976.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG71999.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" PCG77156.1 10 Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-382556 "GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport" PCG72436.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG73759.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" PCG65195.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG71188.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG68735.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500 "Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" PCG76016.1 9 MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-416476 "D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"G alpha (q) signalling events" PCG72789.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" PCG65119.1 4 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" PCG74192.1 5 MetaCyc: PWY-2201;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841 "Folate transformations I";"Metabolism of folate and pterines";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)" PCG75712.1 12 MetaCyc: PWY-6936;MetaCyc: PWY-801;KEGG: 00270+4.4.1.13;MetaCyc: PWY-601;Reactome: R-HSA-71240;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6309;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-7901 "Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Selenocompound metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine" PCG80347.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG68175.1 12 Reactome: R-HSA-416476;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05170+2.7.11.1;Reactome: R-HSA-418885;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (q) signalling events";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"G alpha (12/13) signalling events";"Human immunodeficiency virus 1 infection";"DCC mediated attractive signaling";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"NRAGE signals death through JNK";"Rho GTPase cycle" PCG73605.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions" PCG77378.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG68888.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" PCG77715.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" PCG65196.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" PCG71827.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" PCG80197.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" PCG63424.1 9 Reactome: R-HSA-8963684;KEGG: 00400+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5 "Tyrosine catabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Tyrosine metabolism";"Cysteine and methionine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis" PCG70467.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG77115.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG70441.1 13 KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-7659;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-6383;MetaCyc: PWY-7410 "Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Viridicatumtoxin biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis" PCG69275.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" PCG76707.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" PCG76355.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG72329.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG75743.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG79861.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5743;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle" PCG66989.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG79911.1 8 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Ub-specific processing proteases";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation" PCG73120.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG74272.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG80552.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG74443.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG74134.1 8 KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Galactose metabolism" PCG70459.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" PCG69326.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" PCG75660.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG80767.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG73436.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" PCG75736.1 6 MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" PCG78067.1 52 Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-6807505;Reactome: R-HSA-73780;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-72165;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-76071;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-167290;Reactome: R-HSA-167161;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-167243;Reactome: R-HSA-427413;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-76066;Reactome: R-HSA-6781823;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-6803529 "RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Chain Elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Minor Pathway";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"Pausing and recovery of HIV elongation";"HIV Transcription Initiation";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"Tat-mediated HIV elongation arrest and recovery";"NoRC negatively regulates rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"FGFR2 alternative splicing" PCG67717.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG68990.1 9 Reactome: R-HSA-1362277;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-69017;Reactome: R-HSA-69205 "Transcription of E2F targets under negative control by DREAM complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"G1/S-Specific Transcription" PCG63838.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" PCG66793.1 8 MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis" PCG63375.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG79836.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" PCG72785.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG80361.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" PCG75164.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" PCG64877.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG78907.1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5362768;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257 "Neddylation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN" PCG72356.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" PCG69278.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG77989.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" PCG72358.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" PCG79398.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-2161B;KEGG: 00790+3.4.19.9 "Neutrophil degranulation";"Glutamate removal from folates";"Folate biosynthesis" PCG73280.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG68788.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-141444 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG80241.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" PCG62926.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG74577.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG75285.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" PCG78574.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700 "Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus" PCG77011.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG75064.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG78418.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG70538.1 56 Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-4608870 "Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"Interleukin-1 signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"Asymmetric localization of PCP proteins" PCG81061.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" PCG69938.1 6 MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" PCG76193.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG69268.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG77482.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG76018.1 9 MetaCyc: PWY-7039;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-416476 "Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"G alpha (q) signalling events" PCG68356.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" PCG79580.1 6 Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" PCG81006.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-6791226 "Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG68021.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG79653.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" PCG80613.1 5 MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981 "L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)" PCG80611.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" PCG80988.1 7 KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection" PCG75550.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" PCG74226.1 12 KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-3801;Reactome: R-HSA-3322077;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343 "Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Stachyose degradation";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I" PCG75347.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" PCG75646.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG69195.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic" PCG72371.1 7 MetaCyc: PWY-5484;KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00051+3.1.3.11 "Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism" PCG66875.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" PCG71201.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" PCG71017.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG80969.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" PCG63013.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG72845.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" PCG65045.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" PCG69776.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" PCG62688.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" PCG64298.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" PCG68420.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG72610.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG79902.1 83 Reactome: R-HSA-182971;Reactome: R-HSA-5654700;Reactome: R-HSA-9664565;Reactome: R-HSA-2871796;Reactome: R-HSA-5655291;Reactome: R-HSA-2179392;Reactome: R-HSA-5673001;Reactome: R-HSA-1250347;Reactome: R-HSA-5654712;Reactome: R-HSA-9026519;Reactome: R-HSA-109704;Reactome: R-HSA-179812;Reactome: R-HSA-912631;Reactome: R-HSA-8865999;Reactome: R-HSA-2219530;Reactome: R-HSA-512988;Reactome: R-HSA-5654727;Reactome: R-HSA-8853659;Reactome: R-HSA-5654726;Reactome: R-HSA-9028335;Reactome: R-HSA-5654706;Reactome: R-HSA-2730905;Reactome: R-HSA-8983432;Reactome: R-HSA-354194;Reactome: R-HSA-8853334;Reactome: R-HSA-1236382;Reactome: R-HSA-8875360;Reactome: R-HSA-375165;Reactome: R-HSA-112412;Reactome: R-HSA-389359;Reactome: R-HSA-210993;Reactome: R-HSA-9607240;Reactome: R-HSA-9034864;Reactome: R-HSA-5654719;Reactome: R-HSA-1250196;Reactome: R-HSA-5654695;Reactome: R-HSA-391160;Reactome: R-HSA-5654720;Reactome: R-HSA-180292;Reactome: R-HSA-388841;Reactome: R-HSA-1433559;Reactome: R-HSA-2871809;Reactome: R-HSA-1433557;Reactome: R-HSA-5663213;Reactome: R-HSA-5637810;Reactome: R-HSA-74749;Reactome: R-HSA-5654710;Reactome: R-HSA-983695;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-5655302;Reactome: R-HSA-1963640;Reactome: R-HSA-8853338;Reactome: R-HSA-167044;Reactome: R-HSA-9634285;Reactome: R-HSA-8851805;Reactome: R-HSA-2029482;Reactome: R-HSA-186763;Reactome: R-HSA-1839117;Reactome: R-HSA-2424491;Reactome: R-HSA-5654689;Reactome: R-HSA-5654693;Reactome: R-HSA-180336;Reactome: R-HSA-2428933;Reactome: R-HSA-1963642;Reactome: R-HSA-5654699;Reactome: R-HSA-9027284;Reactome: R-HSA-8856825;Reactome: R-HSA-74751;Reactome: R-HSA-8875656;Reactome: R-HSA-1295596;Reactome: R-HSA-5654688;Reactome: R-HSA-5654733;Reactome: R-HSA-8856828;Reactome: R-HSA-5655253;Reactome: R-HSA-5654704;Reactome: R-HSA-9028731;Reactome: R-HSA-8851907;Reactome: R-HSA-9645135;Reactome: R-HSA-8875555;Reactome: R-HSA-6811558;Reactome: R-HSA-6807004;Reactome: R-HSA-5654732 "EGFR downregulation";"FRS-mediated FGFR2 signaling";"Signaling by ERBB2 KD Mutants";"FCERI mediated MAPK activation";"Signaling by FGFR4 in disease";"EGFR Transactivation by Gastrin";"RAF/MAP kinase cascade";"SHC1 events in ERBB4 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through RAS";"PI3K Cascade";"GRB2 events in EGFR signaling";"Regulation of signaling by CBL";"MET activates PTPN11";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Negative regulation of FGFR2 signaling";"RET signaling";"Negative regulation of FGFR1 signaling";"Activated NTRK2 signals through PI3K";"FRS-mediated FGFR3 signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Interleukin-15 signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by FGFR3 fusions in cancer";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"InlB-mediated entry of Listeria monocytogenes into host cell";"NCAM signaling for neurite out-growth";"SOS-mediated signalling";"CD28 dependent Vav1 pathway";"Tie2 Signaling";"FLT3 Signaling";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR4";"SHC1 events in ERBB2 signaling";"PI-3K cascade:FGFR2";"Signal regulatory protein family interactions";"PI-3K cascade:FGFR4";"GAB1 signalosome";"Costimulation by the CD28 family";"Regulation of KIT signaling";"FCERI mediated Ca+2 mobilization";"Signaling by SCF-KIT";"RHO GTPases Activate WASPs and WAVEs";"Constitutive Signaling by EGFRvIII";"Signal attenuation";"PI-3K cascade:FGFR3";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Signaling by FGFR1 in disease";"GRB2 events in ERBB2 signaling";"Signaling by FGFR3 point mutants in cancer";"Signalling to RAS";"Constitutive Signaling by Overexpressed ERBB2";"MET activates RAS signaling";"Regulation of actin dynamics for phagocytic cup formation";"Downstream signal transduction";"Signaling by cytosolic FGFR1 fusion mutants";"DAP12 signaling";"PI-3K cascade:FGFR1";"FRS-mediated FGFR1 signaling";"SHC1 events in EGFR signaling";"SHC-related events triggered by IGF1R";"PI3K events in ERBB2 signaling";"SHC-mediated cascade:FGFR2";"Erythropoietin activates RAS";"Cargo recognition for clathrin-mediated endocytosis";"Insulin receptor signalling cascade";"MET receptor recycling";"Spry regulation of FGF signaling";"SHC-mediated cascade:FGFR1";"Negative regulation of FGFR4 signaling";"Clathrin-mediated endocytosis";"Signaling by FGFR2 in disease";"SHC-mediated cascade:FGFR3";"Activated NTRK2 signals through FRS2 and FRS3";"MET activates PI3K/AKT signaling";"STAT5 Activation";"MET activates RAP1 and RAC1";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Negative regulation of MET activity";"Negative regulation of FGFR3 signaling" PCG63664.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" PCG77133.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG69028.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" PCG72932.1 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch biosynthesis" PCG72243.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" PCG79092.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG72786.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG67364.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG63158.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG73401.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG69893.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG67194.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" PCG73236.1 10 Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-983231;Reactome: R-HSA-427413 "Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"Factors involved in megakaryocyte development and platelet production";"NoRC negatively regulates rRNA expression" PCG70095.1 26 Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-9646399;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1";"Aggrephagy";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins" PCG78561.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" PCG68377.1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" PCG72132.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG77757.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG76463.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-5649702 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" PCG72735.1 4 Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030 "Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Folate biosynthesis";"Serotonin and melatonin biosynthesis" PCG67330.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway" PCG62561.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG79232.1 7 KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5697;MetaCyc: PWY-7791;MetaCyc: PWY-5698 "Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)";"UMP biosynthesis III";"Allantoin degradation to ureidoglycolate II (ammonia producing)" PCG67181.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG76227.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" PCG78140.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG67681.1 13 MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-561 "Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation" PCG78132.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" PCG77608.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" PCG74077.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695 "Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation" PCG66609.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" PCG78426.1 7 MetaCyc: PWY-8052;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039 "2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" PCG78323.1 13 MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;Reactome: R-HSA-196836;MetaCyc: PWY-7112;MetaCyc: PWY-6370;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-156590;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842 "Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Vitamin C (ascorbate) metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Ascorbate glutathione cycle";"Glutathione metabolism";"Glutathione conjugation";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II" PCG79936.1 18 Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417 "Synthesis of PA";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)" PCG77137.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" PCG78180.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" PCG69210.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" PCG75967.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG80115.1 26 Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-201722 "TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex" PCG75426.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" PCG69159.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG78597.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG63153.1 14 KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4 "Arachidonic acid metabolism";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Ether lipid metabolism" PCG75001.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG74552.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG66930.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG67171.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" PCG67990.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG68269.1 10 MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7199;MetaCyc: PWY-3841;MetaCyc: PWY-7187;Reactome: R-HSA-69205;MetaCyc: PWY-7210;KEGG: 00670+2.1.1.45;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleosides salvage";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"One carbon pool by folate";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" PCG75941.1 14 Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-203927 "Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis" PCG73744.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG70160.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG80929.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" PCG80016.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG69814.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" PCG76813.1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neddylation";"Formation of Incision Complex in GG-NER" PCG71093.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG71320.1 3 KEGG: 00230+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00240+3.6.1.17 "Purine metabolism";"Detoxification of Reactive Oxygen Species";"Pyrimidine metabolism" PCG66089.1 3 MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531 "Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus" PCG77116.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG71085.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG63132.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" PCG74579.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" PCG73486.1 10 KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41 "Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism" PCG75303.1 17 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" PCG67549.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" PCG70744.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" PCG72604.1 4 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" PCG70600.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes" PCG73323.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" PCG75887.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" PCG79700.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-6811436;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"COPI-independent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" PCG62502.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG69411.1 7 Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"Lysine degradation";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" PCG80174.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG78223.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG63383.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG63157.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" PCG76825.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG74546.1 11 MetaCyc: PWY-6549;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7124;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;MetaCyc: PWY-7268;MetaCyc: PWY-5913 "L-glutamine biosynthesis III";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Partial TCA cycle (obligate autotrophs)" PCG69664.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG71824.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG63399.1 1 Reactome: R-HSA-71288 "Creatine metabolism" PCG81129.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" PCG70642.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" PCG69056.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" PCG70892.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG80429.1 12 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Macroautophagy";"Thermogenesis";"Human papillomavirus infection";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"Activation of AMPK downstream of NMDARs";"PI3K-Akt signaling pathway" PCG73332.1 5 Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170 "COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" PCG73254.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" PCG73339.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" PCG70714.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" PCG79016.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection" PCG62435.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" PCG63789.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG65083.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" PCG73624.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" PCG77412.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" PCG76077.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG67927.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" PCG69996.1 3 KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" PCG79057.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" PCG80766.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG80811.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG78868.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" PCG68797.1 4 Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I" PCG71708.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" PCG68136.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" PCG68640.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" PCG76326.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" PCG75240.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG63546.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG76719.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG69596.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG79912.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880 "Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Ub-specific processing proteases" PCG78632.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG75117.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" PCG72372.1 27 Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-77595;Reactome: R-HSA-113418;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-159236;Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-159231;Reactome: R-HSA-975956;Reactome: R-HSA-6803529;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-159227;Reactome: R-HSA-8851708;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-167152 "RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Processing of Intronless Pre-mRNAs";"Formation of the Early Elongation Complex";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"FGFR2 alternative splicing";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Transport of the SLBP independent Mature mRNA";"Signaling by FGFR2 IIIa TM";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat" PCG71316.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-606279 "Fanconi Anemia Pathway";"Deposition of new CENPA-containing nucleosomes at the centromere" PCG71661.1 5 KEGG: 00640+1.2.4.4;Reactome: R-HSA-389661;Reactome: R-HSA-70895;MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4 "Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation" PCG68493.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG76505.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" PCG62870.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" PCG66453.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" PCG79622.1 2 KEGG: 00052+3.2.1.26;KEGG: 00500+3.2.1.26 "Galactose metabolism";"Starch and sucrose metabolism" PCG79233.1 3 MetaCyc: PWY-5698;MetaCyc: PWY-5697;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate II (ammonia producing)";"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" PCG69632.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG77978.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" PCG66245.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG71054.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG72367.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" PCG68353.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" PCG69405.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" PCG72744.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" PCG79257.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" PCG65677.1 4 KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" PCG76629.1 19 MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II" PCG63867.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG65852.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" PCG63127.1 1 Reactome: R-HSA-8949613 "Cristae formation" PCG75603.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG72799.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" PCG73235.1 10 Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-983231 "Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"Factors involved in megakaryocyte development and platelet production" PCG80998.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG73807.1 24 Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-9646399 "COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1";"Aggrephagy" PCG72006.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" PCG81102.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" PCG71563.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG67534.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG66409.1 3 Reactome: R-HSA-3065678;Reactome: R-HSA-983168;Reactome: R-HSA-3065676 "SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)" PCG64604.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" PCG74072.1 1 Reactome: R-HSA-390696 "Adrenoceptors" PCG65165.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination" PCG75372.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5921 "D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation" PCG70569.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" PCG69325.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG68897.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG77823.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" PCG65069.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" PCG68121.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG76706.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" PCG74618.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" PCG65946.1 2 Reactome: R-HSA-442660;Reactome: R-HSA-352230 "Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane" PCG72884.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" PCG75368.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG66219.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" PCG79119.1 4 Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;Reactome: R-HSA-189483;MetaCyc: PWY-5874 "Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation";"Heme degradation I" PCG77919.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" PCG65767.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" PCG64812.1 42 MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5109;MetaCyc: PWY-7654;MetaCyc: PWY-6583;MetaCyc: PWY-5138;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6945;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-6883;MetaCyc: PWY-7778;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656 "4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Aminobenzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to butanol I";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Fatty acid degradation";"Pyruvate fermentation to hexanol (engineered)";"Caprolactam degradation";"Butanoate metabolism";"Fatty acid salvage";"Benzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Phenylalanine metabolism";"Fatty acid elongation";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Limonene and pinene degradation";"Lysine degradation";"Toluene degradation";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Carbon fixation pathways in prokaryotes";"Glutaryl-coa degradation";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol II (engineered)";"2-methylpropene degradation";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis" PCG80210.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" PCG77182.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" PCG70179.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" PCG79674.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277 "Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex" PCG67822.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" PCG75159.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" PCG71595.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG75315.1 4 Reactome: R-HSA-6809583;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864 "Retinoid metabolism disease events";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events" PCG78544.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"Neutrophil degranulation";"RAB geranylgeranylation" PCG62420.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG78628.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" PCG77381.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation" PCG64710.1 6 Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-9022692 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"HCMV Early Events";"Regulation of MECP2 expression and activity" PCG62418.1 10 Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-432720;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383 "Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion" PCG72008.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" PCG76651.1 7 Reactome: R-HSA-2029485;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4 "Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Synthesis of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism" PCG67007.1 1 Reactome: R-HSA-977443 "GABA receptor activation" PCG64717.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" PCG66987.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG78964.1 31 Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5147;MetaCyc: PWY-7746;MetaCyc: PWY-6113;MetaCyc: PWY-5366;MetaCyc: PWY-7858;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5367;MetaCyc: PWY-5973;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWY-6519;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-8047;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6799 "Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Oleate biosynthesis I (plants)";"Mycobacterial sulfolipid biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)" PCG63125.1 9 KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00604+3.2.1.52 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - ganglio series" PCG76437.1 11 Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418594 "Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (i) signalling events" PCG63627.1 2 Reactome: R-HSA-1482798;Reactome: R-HSA-1268020 "Acyl chain remodeling of CL";"Mitochondrial protein import" PCG77219.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" PCG77898.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG79886.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG77628.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG79400.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" PCG70882.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG72878.1 4 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)" PCG77992.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG75116.1 8 MetaCyc: PWY-5269;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668 "Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I" PCG75229.1 20 Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8943724;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-165159 "Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"Macroautophagy";"mTOR signaling pathway";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of PTEN gene transcription";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Thermogenesis";"Regulation of TP53 Degradation";"Human papillomavirus infection";"Amino acids regulate mTORC1";"mTOR signalling" PCG78534.1 3 KEGG: 00970+6.1.1.7;Reactome: R-HSA-5368286;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"Cytosolic tRNA aminoacylation" PCG71083.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG63295.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" PCG72308.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" PCG69779.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" PCG66105.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" PCG63827.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG72867.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" PCG75370.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG73342.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG75928.1 7 Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG71069.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG64817.1 19 Reactome: R-HSA-8964046;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888 "VLDL clearance";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"LDL remodeling";"VLDL assembly";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"LDL clearance";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Regulation of TLR by endogenous ligand";"Chylomicron assembly" PCG78960.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" PCG73483.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" PCG71606.1 1 Reactome: R-HSA-71288 "Creatine metabolism" PCG69923.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" PCG70917.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG76353.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" PCG72635.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG71411.1 57 Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689880;Reactome: R-HSA-532668;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-450408;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-8939236;Reactome: R-HSA-382556;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-69017 "MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Ub-specific processing proteases";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ABC-family proteins mediated transport";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6" PCG63012.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG66748.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-381038 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"XBP1(S) activates chaperone genes" PCG74207.1 17 MetaCyc: PWY-6679;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2 "Jadomycin biosynthesis";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"3-hydroxypropanoate cycle";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"Propanoate metabolism";"Biotin transport and metabolism";"Pyruvate metabolism" PCG70603.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription" PCG78789.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit" PCG78459.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" PCG71345.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" PCG63478.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG62925.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG71747.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG73603.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" PCG73088.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG75628.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7279 "Aerobic respiration I (cytochrome c)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)" PCG65013.1 20 MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7858;MetaCyc: PWY-735;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;Reactome: R-HSA-9033241 "10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid degradation";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import" PCG79729.1 7 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-6798695 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation" PCG77292.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG68868.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG80084.1 7 Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-46;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984 "Urea cycle";"Arginine biosynthesis";"Canavanine degradation";"Putrescine biosynthesis III";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Urea cycle" PCG69330.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG64603.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" PCG64656.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" PCG74587.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG68062.1 29 Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-912446;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-3371511;Reactome: R-HSA-5651801;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-6782210;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Meiotic recombination";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HSF1 activation";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response" PCG76602.1 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" PCG80113.1 26 Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-918233;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-5617472 "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"TRAF3-dependent IRF activation pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" PCG74199.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG72930.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" PCG76859.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG80546.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG80275.1 10 KEGG: 00130+2.1.1.163;MetaCyc: PWY-5892;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5895;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5849;MetaCyc: PWY-5844;MetaCyc: PWY-5890 "Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-10 biosynthesis" PCG77456.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-977225;MetaCyc: PWY-7394;KEGG: 00230+3.5.2.17;MetaCyc: PWY-5691;Reactome: R-HSA-2453864;Reactome: R-HSA-2453902;MetaCyc: PWY-7849;Reactome: R-HSA-3000171 "Neutrophil degranulation";"Retinoid metabolism and transport";"Amyloid fiber formation";"Urate conversion to allantoin II";"Purine metabolism";"Urate conversion to allantoin I";"Retinoid cycle disease events";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions" PCG80502.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG70386.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" PCG80158.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG80072.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" PCG76480.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG62883.1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" PCG79153.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state" PCG68863.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" PCG76166.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901 "Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs" PCG63198.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" PCG73438.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG80887.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-1234176;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-9020702;Reactome: R-HSA-5689880;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768 "Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"Interleukin-1 signaling";"Ub-specific processing proteases";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Orc1 removal from chromatin";"Neddylation";"FCERI mediated NF-kB activation";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" PCG77385.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG65685.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism" PCG67498.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" PCG77110.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" PCG80273.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Macroautophagy";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" PCG70041.1 179 Reactome: R-HSA-6782210;Reactome: R-HSA-2979096;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-2173795;Reactome: R-HSA-912631;Reactome: R-HSA-8939236;Reactome: R-HSA-8948747;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-8863795;Reactome: R-HSA-192823;Reactome: R-HSA-450302;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-5656121;Reactome: R-HSA-6791226;Reactome: R-HSA-5357905;Reactome: R-HSA-5656169;Reactome: R-HSA-202424;Reactome: R-HSA-182971;Reactome: R-HSA-69541;Reactome: R-HSA-174048;Reactome: R-HSA-975144;Reactome: R-HSA-2467813;Reactome: R-HSA-5696394;Reactome: R-HSA-168927;Reactome: R-HSA-977225;Reactome: R-HSA-5687128;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-2173796;Reactome: R-HSA-8876493;Reactome: R-HSA-3785653;Reactome: R-HSA-1358803;Reactome: R-HSA-2173788;Reactome: R-HSA-937041;Reactome: R-HSA-175474;Reactome: R-HSA-5696397;Reactome: R-HSA-9013973;Reactome: R-HSA-983168;Reactome: R-HSA-5654726;Reactome: R-HSA-168928;Reactome: R-HSA-936440;Reactome: R-HSA-5357956;Reactome: R-HSA-72689;Reactome: R-HSA-901032;Reactome: R-HSA-201681;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-72706;Reactome: R-HSA-445989;Reactome: R-HSA-209543;Reactome: R-HSA-937072;Reactome: R-HSA-8866652;Reactome: R-HSA-5693565;Reactome: R-HSA-6804757;Reactome: R-HSA-5655862;Reactome: R-HSA-2559585;Reactome: R-HSA-8852276;Reactome: R-HSA-5675221;Reactome: R-HSA-110312;Reactome: R-HSA-2559582;Reactome: R-HSA-110314;Reactome: R-HSA-69231;Reactome: R-HSA-2408557;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-9615710;Reactome: R-HSA-5654733;Reactome: R-HSA-5696395;Reactome: R-HSA-917729;Reactome: R-HSA-1799339;Reactome: R-HSA-8951664;Reactome: R-HSA-9637628;Reactome: R-HSA-5668541;Reactome: R-HSA-6782135;Reactome: R-HSA-9033241;Reactome: R-HSA-156827;Reactome: R-HSA-5675482;Reactome: R-HSA-975957;Reactome: R-HSA-69481;Reactome: R-HSA-9636383;Reactome: R-HSA-4608870;Reactome: R-HSA-975956;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-4641263;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-917937;Reactome: R-HSA-936964;Reactome: R-HSA-9010553;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-937042;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-2122947;Reactome: R-HSA-975110;Reactome: R-HSA-9633012;Reactome: R-HSA-1169408;Reactome: R-HSA-6781823;Reactome: R-HSA-5685942;Reactome: R-HSA-8849469;Reactome: R-HSA-5689896;Reactome: R-HSA-2894862;Reactome: R-HSA-1169091;Reactome: R-HSA-8948751;Reactome: R-HSA-532668;Reactome: R-HSA-2871837;Reactome: R-HSA-8875360;Reactome: R-HSA-9613829;Reactome: R-HSA-68949;Reactome: R-HSA-1236382;Reactome: R-HSA-5693607;Reactome: R-HSA-2173791;Reactome: R-HSA-110320;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-5362768;Reactome: R-HSA-1253288;Reactome: R-HSA-2559580;Reactome: R-HSA-3322077;Reactome: R-HSA-5632684;Reactome: R-HSA-5654727;Reactome: R-HSA-205043;Reactome: R-HSA-450321;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-72764;Reactome: R-HSA-2691232;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-1236974;Reactome: R-HSA-5205685;Reactome: R-HSA-9014325;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-975163;Reactome: R-HSA-209560;Reactome: R-HSA-8866654;Reactome: R-HSA-2672351;Reactome: R-HSA-5689877;Reactome: R-HSA-168638;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-6781827;Reactome: R-HSA-3769402;Reactome: R-HSA-5684264;Reactome: R-HSA-5654732;Reactome: R-HSA-174490;Reactome: R-HSA-195253;Reactome: R-HSA-9013507;Reactome: R-HSA-156902;Reactome: R-HSA-1295596;Reactome: R-HSA-8856825;Reactome: R-HSA-162588;Reactome: R-HSA-5696400;Reactome: R-HSA-2565942;Reactome: R-HSA-450408;Reactome: R-HSA-6804760;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-6783310;Reactome: R-HSA-3134975 "Gap-filling DNA repair synthesis and ligation in TC-NER";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of signaling by CBL";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN localization";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Downregulation of ERBB2 signaling";"Viral mRNA Translation";"activated TAK1 mediates p38 MAPK activation";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Translesion synthesis by POLI";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of TNFR1 signaling";"Termination of translesion DNA synthesis";"Downstream TCR signaling";"EGFR downregulation";"Stabilization of p53";"APC/C:Cdc20 mediated degradation of Cyclin B";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Separation of Sister Chromatids";"DNA Damage Recognition in GG-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"Amyloid fiber formation";"MAPK6/MAPK4 signaling";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"InlA-mediated entry of Listeria monocytogenes into host cells";"Myoclonic epilepsy of Lafora";"Downregulation of ERBB2:ERBB3 signaling";"Downregulation of TGF-beta receptor signaling";"IKK complex recruitment mediated by RIP1";"Assembly Of The HIV Virion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"TICAM1-dependent activation of IRF3/IRF7";"Antigen processing: Ubiquitination & Proteasome degradation";"Negative regulation of FGFR1 signaling";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Negative regulators of DDX58/IFIH1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Formation of a pool of free 40S subunits";"ER Quality Control Compartment (ERQC)";"TCF dependent signaling in response to WNT";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"p75NTR recruits signalling complexes";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Degradation";"Translesion synthesis by POLK";"Oncogene Induced Senescence";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of MAPK pathway";"Translesion synthesis by REV1";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition of DNA damage by PCNA-containing replication complex";"Cyclin D associated events in G1";"Selenocysteine synthesis";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"Late endosomal microautophagy";"Negative regulation of FGFR4 signaling";"Formation of Incision Complex in GG-NER";"Endosomal Sorting Complex Required For Transport (ESCRT)";"SRP-dependent cotranslational protein targeting to membrane";"Neddylation";"Modulation by Mtb of host immune system";"TNFR2 non-canonical NF-kB pathway";"Dual incision in TC-NER";"Peroxisomal protein import";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of necroptotic cell death";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"G2/M Checkpoints";"Prevention of phagosomal-lysosomal fusion";"Asymmetric localization of PCP proteins";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of FZD by ubiquitination";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Iron uptake and transport";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of expression of SLITs and ROBOs";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"IRAK2 mediated activation of TAK1 complex";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ISG15 antiviral mechanism";"Formation of TC-NER Pre-Incision Complex";"HDR through Homologous Recombination (HRR)";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Ovarian tumor domain proteases";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of NF-kappaB in B cells";"Regulation of PTEN stability and activity";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"FCERI mediated NF-kB activation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Chaperone Mediated Autophagy";"Orc1 removal from chromatin";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Processing of DNA double-strand break ends";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Translesion Synthesis by POLH";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB4 signaling";"Oxidative Stress Induced Senescence";"Glycogen synthesis";"Hedgehog 'on' state";"Negative regulation of FGFR2 signaling";"NRIF signals cell death from the nucleus";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Eukaryotic Translation Termination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"ER-Phagosome pathway";"Pink/Parkin Mediated Mitophagy";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Metalloprotease DUBs";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"NF-kB is activated and signals survival";"E3 ubiquitin ligases ubiquitinate target proteins";"Stimuli-sensing channels";"Josephin domain DUBs";"NOD1/2 Signaling Pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Deactivation of the beta-catenin transactivating complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of FGFR3 signaling";"Membrane binding and targetting of GAG proteins";"Degradation of beta-catenin by the destruction complex";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Peptide chain elongation";"Spry regulation of FGF signaling";"Cargo recognition for clathrin-mediated endocytosis";"Budding and maturation of HIV virion";"Dual Incision in GG-NER";"Regulation of PLK1 Activity at G2/M Transition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of TP53 Activity through Methylation";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Fanconi Anemia Pathway";"Regulation of innate immune responses to cytosolic DNA" PCG71987.1 1 Reactome: R-HSA-203615 "eNOS activation" PCG79141.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" PCG68170.1 6 MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6118 "Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Synthesis of PA";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle" PCG71062.1 7 Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-6840;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255 "Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Homoglutathione biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)" PCG72225.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG71197.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" PCG80898.1 4 KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis" PCG72131.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" PCG67048.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" PCG80384.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-170660 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Adenylate cyclase activating pathway" PCG66466.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG71526.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" PCG66152.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" PCG74279.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG79024.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" PCG74599.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG67024.1 8 MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle" PCG78565.1 8 Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" PCG77414.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" PCG69850.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG77222.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG75304.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" PCG76092.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" PCG71313.1 13 MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism" PCG70833.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG72234.1 52 Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-5578749;Reactome: R-HSA-76066;Reactome: R-HSA-167243;Reactome: R-HSA-427413;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-167238;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-72165;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-9018519;Reactome: R-HSA-73780;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6807505;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-73776 "FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated HIV elongation arrest and recovery";"NoRC negatively regulates rRNA expression";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Estrogen-dependent gene expression";"RNA Polymerase III Chain Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape" PCG68388.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" PCG74784.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG71255.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG77902.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" PCG66482.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" PCG76271.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" PCG66909.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" PCG71322.1 5 Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948 "Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants" PCG72236.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase" PCG77308.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" PCG75371.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG65980.1 5 Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695 "STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation" PCG78610.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" PCG81121.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" PCG74284.1 12 Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-75893;Reactome: R-HSA-5362798;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-2122948;Reactome: R-HSA-193692;Reactome: R-HSA-2894862 "Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"TNF signaling";"Release of Hh-Np from the secreting cell";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" PCG68334.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG75306.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" PCG72016.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG78908.1 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" PCG77335.1 5 Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-6798695 "Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Neutrophil degranulation" PCG70688.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" PCG67225.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" PCG78810.1 4 Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" PCG78523.1 3 Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-4608870 "Class B/2 (Secretin family receptors)";"PCP/CE pathway";"Asymmetric localization of PCP proteins" PCG71845.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG75380.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" PCG79647.1 8 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG70185.1 13 MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-6383;MetaCyc: PWY-7410;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7659;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7102 "Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)" PCG62410.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG72369.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG63755.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG70697.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG66652.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" PCG69593.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG80394.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination" PCG76718.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG68327.1 6 KEGG: 00052+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7395;MetaCyc: PWY-7077 "Galactose metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation" PCG76446.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG66449.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" PCG67512.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" PCG75542.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" PCG75115.1 8 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;Reactome: R-HSA-1483148 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Synthesis of PG" PCG68594.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG71993.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" PCG80629.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" PCG69973.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" PCG79837.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" PCG64087.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" PCG78007.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" PCG75055.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-3238698 "Neutrophil degranulation";"WNT ligand biogenesis and trafficking" PCG70263.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" PCG63688.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" PCG75973.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" PCG72736.1 4 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "UCH proteinases";"HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" PCG68230.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG66555.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" PCG75424.1 1 Reactome: R-HSA-5689603 "UCH proteinases" PCG71418.1 12 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" PCG71198.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" PCG76950.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" PCG64537.1 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817 "Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis" PCG66485.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" PCG73606.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG75475.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids" PCG76588.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" PCG69058.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" PCG67188.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" PCG74483.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane" PCG68296.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG64945.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" PCG72706.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG65055.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168333 "Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery" PCG70154.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" PCG75207.1 13 Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-5689877;Reactome: R-HSA-8866654;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-110320 "Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Josephin domain DUBs";"E3 ubiquitin ligases ubiquitinate target proteins";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"HSF1 activation";"Ovarian tumor domain proteases";"Protein methylation";"Translesion Synthesis by POLH" PCG64910.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG74013.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG75930.1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Regulation of HSF1-mediated heat shock response";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Cristae formation" PCG62569.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" PCG78888.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG78184.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"MHC class II antigen presentation" PCG77211.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" PCG67637.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" PCG74362.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG74190.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" PCG74525.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG67647.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" PCG77106.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" PCG66211.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" PCG64016.1 3 Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569 "ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" PCG69024.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG70839.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" PCG63047.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" PCG72629.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" PCG65494.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" PCG66910.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG74005.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG76294.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" PCG76066.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" PCG75976.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" PCG68590.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" PCG68278.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG75857.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG76868.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG77063.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" PCG71347.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" PCG70624.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" PCG79842.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling" PCG78889.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" PCG65509.1 4 Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6 "Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" PCG78834.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"Ion channel transport" PCG69064.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" PCG66122.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG77046.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" PCG65470.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing" PCG73721.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG75463.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG72577.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG76479.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG78065.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG71087.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG71499.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" PCG77471.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG70069.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" PCG69732.1 15 MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-6901;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5723;KEGG: 00230+2.7.1.40;MetaCyc: PWY-8004;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-7003 "Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Purine metabolism";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol" PCG69907.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" PCG68308.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" PCG66246.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG63398.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" PCG78581.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" PCG65783.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" PCG69422.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" PCG64111.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG73867.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001 "MHC class II antigen presentation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sialic acid metabolism" PCG62874.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-350562 "Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of DVL";"Hedgehog ligand biogenesis";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of ornithine decarboxylase (ODC)" PCG76051.1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" PCG65661.1 5 MetaCyc: PWY-7185;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6 "UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine metabolism" PCG63443.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" PCG65757.1 26 Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-174414;Reactome: R-HSA-174411;Reactome: R-HSA-4615885;Reactome: R-HSA-69183;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-6804114;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-1362277 "Translesion synthesis by POLK";"Dual Incision in GG-NER";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere";"SUMOylation of DNA replication proteins";"Processive synthesis on the lagging strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"G1/S-Specific Transcription";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Transcription of E2F targets under negative control by DREAM complex" PCG73996.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG71065.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" PCG66250.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG67312.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" PCG76141.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG79531.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" PCG63146.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG72159.1 13 KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883 "Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II" PCG68285.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG68167.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG80947.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" PCG73875.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG62692.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG72829.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG67408.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" PCG66673.1 7 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" PCG71955.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" PCG74766.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" PCG75206.1 13 Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-382556;Reactome: R-HSA-9646399;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-8876725;Reactome: R-HSA-110320;Reactome: R-HSA-5689896;Reactome: R-HSA-6798695;Reactome: R-HSA-8866654;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768 "Hedgehog ligand biogenesis";"HSF1 activation";"ABC-family proteins mediated transport";"Aggrephagy";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein methylation";"Translesion Synthesis by POLH";"Ovarian tumor domain proteases";"Neutrophil degranulation";"E3 ubiquitin ligases ubiquitinate target proteins";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" PCG64240.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG66134.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" PCG76679.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" PCG80130.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" PCG68887.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" PCG79754.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion" PCG68415.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" PCG79595.1 18 MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Reductive TCA cycle II";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes" PCG69410.1 7 MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71403;KEGG: 00380+2.3.1.61 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism" PCG67088.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" PCG77508.1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8963901 "Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"LDL remodeling";"VLDL assembly";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Scavenging by Class B Receptors";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"Chylomicron remodeling" PCG63762.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG71514.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG77933.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" PCG68784.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" PCG67556.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG74000.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit" PCG63280.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" PCG70385.1 6 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427359 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression" PCG70687.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" PCG79406.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG73174.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695 "Tryptophan metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation" PCG75036.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" PCG78126.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG70309.1 1 Reactome: R-HSA-420029 "Tight junction interactions" PCG66367.1 5 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis" PCG80702.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" PCG70074.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG67090.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" PCG65285.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" PCG67058.1 16 Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-674695 "Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events" PCG74759.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" PCG71862.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG79404.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" PCG70072.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" PCG69611.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" PCG79010.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway" PCG78112.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG77677.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway" PCG71068.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" PCG63566.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG68736.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500 "Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" PCG73067.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" PCG71510.1 8 MetaCyc: PWY-5740;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5739;KEGG: 00051+4.2.1.47 "GDP-L-colitose biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-D-perosamine biosynthesis";"Fructose and mannose metabolism" PCG64939.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" PCG79138.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" PCG69717.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" PCG70888.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" PCG78902.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG72437.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" PCG79148.1 4 KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;MetaCyc: PWY-7250;Reactome: R-HSA-1362409 "Thiamine metabolism";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" PCG66255.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism" PCG65225.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" PCG76892.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG78399.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" PCG75642.1 15 Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519 "TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression" PCG66808.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG71206.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" PCG79505.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" PCG76110.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.1;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1 "Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms" PCG78068.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" PCG76958.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" PCG65193.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG79910.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Dual incision in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" PCG80458.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" PCG81051.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG75846.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" PCG70924.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" PCG68578.1 3 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984 "One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation" PCG71669.1 6 MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530 "L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Pentose phosphate pathway";"Sorbitol biosynthesis II" PCG67548.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" PCG72988.1 6 MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis" PCG79753.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" PCG68168.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" PCG74484.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG64527.1 4 Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695 "Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation" PCG78793.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" PCG72477.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG64161.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)" PCG76896.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" PCG70584.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" PCG73474.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG63568.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG74376.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" PCG79025.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" PCG73330.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-204005 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport" PCG70843.1 8 Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" PCG75300.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG67400.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" PCG65654.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG66608.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG75586.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG74248.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" PCG73881.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" PCG69267.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" PCG68061.1 29 Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-912446;Reactome: R-HSA-5651801;Reactome: R-HSA-3371511;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Meiotic recombination";"PCNA-Dependent Long Patch Base Excision Repair";"HSF1 activation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" PCG78524.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-983168 "Transcriptional Regulation by VENTX";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation" PCG80854.1 57 Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-1236978;Reactome: R-HSA-5687128;Reactome: R-HSA-5689880;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-8939902;Reactome: R-HSA-174084;Reactome: R-HSA-1234176;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-69481;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-75815;Reactome: R-HSA-382556;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Neddylation";"Orc1 removal from chromatin";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"MAPK6/MAPK4 signaling";"Ub-specific processing proteases";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Regulation of RUNX2 expression and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"G2/M Checkpoints";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin-dependent degradation of Cyclin D";"ABC-family proteins mediated transport";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling" PCG66005.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" PCG77010.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG68682.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" PCG80451.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" PCG79775.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG64136.1 1 Reactome: R-HSA-211981 "Xenobiotics" PCG68180.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" PCG64490.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" PCG72085.1 9 Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;KEGG: 00010+1.2.1.12;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-8004 "Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I" PCG63420.1 18 KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483166 "Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA" PCG68659.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG63946.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG66223.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG76405.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG69846.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG79923.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG64500.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" PCG79736.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" PCG77183.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" PCG75390.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" PCG71707.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-7214 "Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)" PCG65402.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" PCG71792.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" PCG80825.1 11 KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-7782;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8053 "Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis II" PCG76269.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" PCG77741.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" PCG76012.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG73858.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" PCG80331.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" PCG66661.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG62963.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" PCG63255.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG75244.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG64050.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" PCG62826.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG80970.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" PCG67221.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" PCG67504.1 40 KEGG: 00623+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6945;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-5177;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-5789;MetaCyc: PWY-6883;MetaCyc: PWY-7778;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00360+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-6583;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7401;MetaCyc: PWY-6435;MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5109;MetaCyc: PWY-7654 "Toluene degradation";"Methyl ketone biosynthesis (engineered)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Glutaryl-coa degradation";"Carbon fixation pathways in prokaryotes";"Androstenedione degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Pyruvate fermentation to butanol II (engineered)";"2-methylpropene degradation";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Phenylalanine metabolism";"Fatty acid elongation";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Limonene and pinene degradation";"Lysine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Pyruvate fermentation to butanol I";"Caprolactam degradation";"Pyruvate fermentation to hexanol (engineered)";"Butanoate metabolism";"Fatty acid salvage";"Benzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"4-hydroxybenzoate biosynthesis III (plants)";"Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"alpha-Linolenic acid metabolism";"Tryptophan metabolism";"Aminobenzoate degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"(8E,10E)-dodeca-8,10-dienol biosynthesis" PCG77136.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964 "MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" PCG71179.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" PCG75223.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG73319.1 6 Reactome: R-HSA-6803205;Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-139915;Reactome: R-HSA-6803207 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases" PCG80226.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" PCG69177.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG72644.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" PCG73555.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG71445.1 2 KEGG: 00970+6.1.1.9;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" PCG79988.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" PCG77407.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation" PCG81100.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" PCG77476.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001 "MHC class II antigen presentation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism" PCG77014.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion" PCG76196.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" PCG71187.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG77096.1 1 Reactome: R-HSA-5676934 "Protein repair" PCG64977.1 1 Reactome: R-HSA-5676934 "Protein repair" PCG65221.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG69723.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" PCG68338.1 9 Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-3928662;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066 "Long-term potentiation";"RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"EPHB-mediated forward signaling";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation" PCG63639.1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-400206 "RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha" PCG73815.1 3 KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129;Reactome: R-HSA-1660661 "Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis" PCG77135.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" PCG63152.1 13 Reactome: R-HSA-380972;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757 "Energy dependent regulation of mTOR by LKB1-AMPK";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Macroautophagy";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation" PCG68065.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" PCG76587.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" PCG74195.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517 "Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II" PCG73660.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG62603.1 14 MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724 "Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" PCG63662.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" PCG65162.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-162658 "COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization" PCG69910.1 1 Reactome: R-HSA-5689603 "UCH proteinases" PCG63865.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG74110.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" PCG65977.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA" PCG78420.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG63261.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" PCG66006.1 6 Reactome: R-HSA-3878781;MetaCyc: PWY-7900;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;Reactome: R-HSA-3322077 "Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen synthesis" PCG73784.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7619 "Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Juniperonate biosynthesis" PCG79750.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG76450.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG73134.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" PCG65268.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811436 "Cilium Assembly";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-independent Golgi-to-ER retrograde traffic" PCG80124.1 26 Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-3899300;Reactome: R-HSA-918233 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"TRAF3-dependent IRF activation pathway" PCG72813.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" PCG73116.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG80074.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" PCG64198.1 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" PCG65978.1 5 Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695 "STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation" PCG68043.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" PCG71121.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" PCG77646.1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation" PCG64853.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG76376.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" PCG71903.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG77125.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" PCG63528.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" PCG62626.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" PCG65725.1 1 Reactome: R-HSA-211981 "Xenobiotics" PCG80116.1 26 Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-400253;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-9614657 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Circadian Clock";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"FOXO-mediated transcription of cell death genes" PCG70960.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane" PCG71502.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" PCG71820.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" PCG67092.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" PCG77758.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG64575.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-5972 "Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)" PCG72775.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921 "EPHB-mediated forward signaling";"Downstream signal transduction";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation" PCG80625.1 1 Reactome: R-HSA-1632852 "Macroautophagy" PCG76234.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" PCG67791.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" PCG66254.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" PCG63361.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" PCG71670.1 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17 "Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Caprolactam degradation" PCG63162.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" PCG75506.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" PCG77031.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" PCG71506.1 2 Reactome: R-HSA-9627069;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"Formation of apoptosome" PCG72504.1 13 MetaCyc: PWY-7909;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722 "Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"L-histidine degradation III";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Folate transformations I";"Folate polyglutamylation";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate" PCG76550.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" PCG78593.1 1 Reactome: R-HSA-6798163 "Choline catabolism" PCG75869.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" PCG73406.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" PCG74859.1 1 Reactome: R-HSA-74217 "Purine salvage" PCG65632.1 12 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-975956;Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-72662 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S" PCG71357.1 19 MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136 "(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)" PCG67731.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" PCG63414.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG63285.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" PCG67783.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638 "Separation of Sister Chromatids";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" PCG78395.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" PCG68851.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" PCG62811.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG66068.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" PCG77821.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" PCG67251.1 6 Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346;MetaCyc: PWY-7820 "Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Teichuronic acid biosynthesis (B. subtilis 168)" PCG65851.1 11 Reactome: R-HSA-168138;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137 "Toll Like Receptor 9 (TLR9) Cascade";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism" PCG73720.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG69429.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" PCG79017.1 7 KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway" PCG80017.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" PCG63233.1 13 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Retrograde neurotrophin signalling";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" PCG62434.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG65001.1 20 MetaCyc: PWY-7007;MetaCyc: PWY-6837;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7340;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7726 "Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Propanoyl-coa degradation II";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"beta-Alanine metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" PCG76111.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis" PCG71988.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" PCG75471.1 31 MetaCyc: PWY-8012;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-5994;MetaCyc: PWY-6519;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-7388;MetaCyc: PWY-5142;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-4381;MetaCyc: PWY-6799;MetaCyc: PWY-7664;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-7746;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-5966-1;MetaCyc: PWY-5989;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5367;MetaCyc: PWY-5973;MetaCyc: PWY-7723 "Mupirocin biosynthesis";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"Pederin biosynthesis";"";"Gondoate biosynthesis (anaerobic)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Stearate biosynthesis II (bacteria and plants)";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence" PCG66407.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" PCG65773.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" PCG80269.1 14 Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Macroautophagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" PCG71848.1 3 Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590 "Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation" PCG80119.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-5621575;Reactome: R-HSA-9614657;Reactome: R-HSA-9617629;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508 "RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"CD209 (DC-SIGN) signaling";"FOXO-mediated transcription of cell death genes";"Regulation of FOXO transcriptional activity by acetylation";"Circadian Clock";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription" PCG66872.1 7 Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" PCG65366.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG64430.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" PCG74767.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" PCG64502.1 6 KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364 "Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis" PCG80455.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" PCG74053.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" PCG69734.1 6 MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391 "Mevalonate pathway I";"Cholesterol biosynthesis";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" PCG77760.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" PCG77653.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" PCG75701.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG74440.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" PCG71513.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" PCG66257.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403 "Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling" PCG72833.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" PCG72228.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" PCG69713.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" PCG67257.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" PCG71115.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG64096.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" PCG66153.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG65241.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" PCG75414.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" PCG79594.1 18 MetaCyc: PWY-6728;MetaCyc: PWY-7383;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115 "Methylaspartate cycle";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Reductive TCA cycle II";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" PCG65820.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" PCG63788.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" PCG73402.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG64543.1 11 MetaCyc: PWY-5675;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6964;Reactome: R-HSA-8964539;KEGG: 00910+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6549;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2 "Nitrate reduction V (assimilatory)";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle II";"Glutamate and glutamine metabolism";"Nitrogen metabolism";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism" PCG64024.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" PCG63692.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" PCG74052.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" PCG79799.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" PCG80271.1 14 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5620924;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-1632852 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"Intraflagellar transport";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Macroautophagy" PCG74535.1 24 Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-416482;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-6814122;Reactome: R-HSA-420092;Reactome: R-HSA-432040;Reactome: R-HSA-500657;Reactome: R-HSA-8964315;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-418555 "G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G alpha (12/13) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-type ligand receptors";"Vasopressin regulates renal water homeostasis via Aquaporins";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through BTK";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (s) signalling events" PCG77744.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids" PCG70133.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG73502.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" PCG69157.1 2 KEGG: 00230+3.5.3.4;MetaCyc: PWY-5697 "Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)" PCG77612.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-1268020 "Processing of SMDT1";"Mitochondrial protein import" PCG65756.1 26 Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-1362277;Reactome: R-HSA-5656121;Reactome: R-HSA-6804114;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-69205;Reactome: R-HSA-110312;Reactome: R-HSA-8866654;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-69183;Reactome: R-HSA-4615885;Reactome: R-HSA-174414;Reactome: R-HSA-174411 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLI";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Termination of translesion DNA synthesis";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"G1/S-Specific Transcription";"Translesion synthesis by REV1";"E3 ubiquitin ligases ubiquitinate target proteins";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Processive synthesis on the lagging strand";"SUMOylation of DNA replication proteins";"Processive synthesis on the C-strand of the telomere";"Polymerase switching on the C-strand of the telomere" PCG67907.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" PCG76551.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG66256.1 5 KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3 "Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism" PCG81072.1 1 Reactome: R-HSA-8951664 "Neddylation" PCG76390.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" PCG68386.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" PCG62693.1 6 Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205 "Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" PCG76773.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" PCG78503.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" PCG65653.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" PCG72422.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" PCG72491.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" PCG75012.1 16 Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-201722;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Formation of the beta-catenin:TCF transactivating complex";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence" PCG72702.1 5 Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;MetaCyc: PWY-6558 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)" PCG80477.1 1 Reactome: R-HSA-6783984 "Glycine degradation" PCG75982.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" PCG67205.1 6 KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-7356;MetaCyc: PWY-6908 "Thiamine metabolism";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)" PCG71153.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" PCG70756.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" PCG63675.1 14 MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-6433 "Sciadonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)" PCG69619.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" PCG67682.1 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-561 "Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation" PCG74581.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" PCG74087.1 11 Reactome: R-HSA-450302;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "activated TAK1 mediates p38 MAPK activation";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"p38MAPK events";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" PCG77045.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG77329.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG75617.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG69967.1 8 MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7197;MetaCyc: PWY-7198;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates" PCG78469.1 24 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-380320;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-5663220;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-9646399;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-437239 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases Activate Formins";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Aggrephagy";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1" PCG76434.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" PCG73933.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" PCG76672.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-2024096;Reactome: R-HSA-2206291 "Neutrophil degranulation";"HS-GAG degradation";"MPS IIIC - Sanfilippo syndrome C" PCG77470.1 18 KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6642;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7383 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Tyrosine metabolism";"Coenzyme M biosynthesis II";"Cysteine and methionine metabolism";"Sulfolactate degradation III";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"(R)-cysteate degradation";"Isoquinoline alkaloid biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)" PCG69750.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" PCG64480.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" PCG70643.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" PCG76277.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG67532.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" PCG73613.1 29 Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-6796648;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167246;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73772;Reactome: R-HSA-167172;Reactome: R-HSA-167160 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Promoter Escape";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" PCG64873.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG69114.1 18 KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1 "Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Sulfolactate degradation III";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Novobiocin biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis" PCG81004.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" PCG68706.1 3 Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport" PCG68803.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" PCG76522.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" PCG65510.1 4 KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;Reactome: R-HSA-196757 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Metabolism of folate and pterines" PCG69026.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" PCG70148.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" PCG75249.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" PCG62940.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" PCG68456.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" PCG78611.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" PCG76412.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" PCG64241.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" PCG77848.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" PCG72466.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" PCG75237.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" PCG72552.1 8 KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1 "Starch and sucrose metabolism";"Galactose metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" PCG77234.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" PCG75472.1 31 KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-7664;MetaCyc: PWY-4381;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-8012;MetaCyc: PWY-6519;MetaCyc: PWY-5994;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-8047;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-7723;MetaCyc: PWY-5367;MetaCyc: PWY-5973;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7746;MetaCyc: PWY-5147;MetaCyc: PWY-6113;MetaCyc: PWY-7858;MetaCyc: PWY-5366 "Fatty acid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Mupirocin biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"";"Gondoate biosynthesis (anaerobic)";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Bacterial bioluminescence";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis I (plants)";"Superpathway of mycolate biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)" PCG72983.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-7328;MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2 "Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism" PCG62812.1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)" PCG80118.1 26 Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-201722;Reactome: R-HSA-381340;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-2894862;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-9614657;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9013695;Reactome: R-HSA-918233;Reactome: R-HSA-3899300;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Formation of the beta-catenin:TCF transactivating complex";"Transcriptional regulation of white adipocyte differentiation";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"Circadian Clock";"FOXO-mediated transcription of cell death genes";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"SUMOylation of transcription cofactors";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression" PCG77184.1 1 Reactome: R-HSA-156588 "Glucuronidation" PCG70656.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" PCG79874.1 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis" PCG64268.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" PCG63167.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" PCG72281.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" PCG72030.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" PCG69686.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" PCG63391.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation"