Accession_ID Pathway_Count Pathway_IDs Pathway_Names maker-scaffold2size2657229-augustus-gene-13.3-mRNA-1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" maker-scaffold39size909063-augustus-gene-1.2-mRNA-1 5 MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391 "Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" maker-scaffold5size1727520-augustus-gene-4.4-mRNA-1 5 MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" maker-scaffold886size39735-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-189200 "SRP-dependent cotranslational protein targeting to membrane";"Cellular hexose transport" maker-scaffold75size670735-augustus-gene-1.5-mRNA-1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" maker-scaffold275size262729-augustus-gene-1.1-mRNA-1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" maker-scaffold169size953240-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" maker-scaffold80size1421260-augustus-gene-9.2-mRNA-1 1 Reactome: R-HSA-70921 "Histidine catabolism" augustus-scaffold4866size3213-processed-gene-0.0-mRNA-1 6 Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold22size1201825-augustus-gene-5.6-mRNA-1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" maker-scaffold85size629767-augustus-gene-5.1-mRNA-1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" maker-scaffold10size1426409-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold30size1054049-augustus-gene-0.0-mRNA-1 6 Reactome: R-HSA-189085;MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18 "Digestion of dietary carbohydrate";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism" maker-scaffold24size1136029-augustus-gene-9.0-mRNA-1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" maker-scaffold382size176025-augustus-gene-0.4-mRNA-1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" augustus-scaffold1196size24650-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold42size1661181-augustus-gene-1.4-mRNA-1 3 Reactome: R-HSA-525793;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220 "Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins" maker-scaffold25size1130848-augustus-gene-7.4-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold105size529344-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold120size483217-augustus-gene-3.4-mRNA-1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" maker-scaffold1size2756217-augustus-gene-6.6-mRNA-1 6 Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-73930;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-110362 "PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"POLB-Dependent Long Patch Base Excision Repair" maker-scaffold22size1201825-augustus-gene-7.6-mRNA-1 17 Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-176412 "Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C" maker-scaffold602size77912-augustus-gene-0.8-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold122size477764-augustus-gene-1.5-mRNA-1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" maker-scaffold24size1136029-augustus-gene-3.11-mRNA-1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" maker-scaffold484size118506-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold20size1234842-augustus-gene-8.3-mRNA-1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" maker-scaffold45size832949-augustus-gene-3.3-mRNA-1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" maker-scaffold18size2240851-augustus-gene-4.8-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold50size801739-augustus-gene-7.10-mRNA-1 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" maker-scaffold869size42088-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" augustus-scaffold343size209053-processed-gene-1.1-mRNA-1 22 Reactome: R-HSA-6790901;Reactome: R-HSA-6799198;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-110357;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-611105;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-110330;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-110331;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "rRNA modification in the nucleus and cytosol";"Complex I biogenesis";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Displacement of DNA glycosylase by APEX1";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Respiratory electron transport";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Recognition and association of DNA glycosylase with site containing an affected purine";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Cleavage of the damaged purine";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" maker-scaffold629size81683-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold36size1013817-augustus-gene-4.23-mRNA-1 3 Reactome: R-HSA-381038;Reactome: R-HSA-72163;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"mRNA Splicing - Major Pathway";"SRP-dependent cotranslational protein targeting to membrane" maker-scaffold455size140735-augustus-gene-0.8-mRNA-1 5 Reactome: R-HSA-71336;Reactome: R-HSA-6798695;MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060 "Pentose phosphate pathway";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I" maker-scaffold42size1661181-augustus-gene-15.8-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold1232size23669-augustus-gene-0.1-mRNA-1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" maker-scaffold22size1201825-augustus-gene-7.9-mRNA-1 14 KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5076;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5103;MetaCyc: PWY-5108;MetaCyc: PWY-5078 "Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"L-leucine degradation III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis V";"L-isoleucine degradation II" maker-scaffold65size703589-augustus-gene-1.3-mRNA-1 3 Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation" maker-scaffold80size1421260-augustus-gene-9.0-mRNA-1 4 Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6782315 "rRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol" maker-scaffold73size681921-augustus-gene-5.5-mRNA-1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold28size1079920-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" maker-scaffold59size767954-augustus-gene-3.11-mRNA-1 19 Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-975634 "Post-translational protein phosphorylation";"VLDL assembly";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL remodeling";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class H Receptors";"Retinoid metabolism and transport" maker-scaffold110size515606-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" maker-scaffold8086size1447-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" maker-scaffold9size1444705-augustus-gene-11.0-mRNA-1 6 Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-5632684 "RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state" maker-scaffold78size655360-augustus-gene-5.2-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold2906size7753-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold214size663695-augustus-gene-3.1-mRNA-1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" maker-scaffold5size1727520-augustus-gene-13.5-mRNA-1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" maker-scaffold37size976698-augustus-gene-7.0-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold11size1424826-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" maker-scaffold1size2756217-augustus-gene-26.5-mRNA-1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" maker-scaffold2853size7944-augustus-gene-0.1-mRNA-1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" maker-scaffold513size110971-augustus-gene-0.4-mRNA-1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-166208 "Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling" maker-scaffold145size712617-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-352230;Reactome: R-HSA-442660 "Amino acid transport across the plasma membrane";"Na+/Cl- dependent neurotransmitter transporters" maker-scaffold1879size21166-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" maker-scaffold342size295439-augustus-gene-1.10-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold37size976698-augustus-gene-0.3-mRNA-1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" maker-scaffold6size1916839-augustus-gene-14.3-mRNA-1 4 Reactome: R-HSA-3371453;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613 "Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation" maker-scaffold5132size3087-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" maker-scaffold70size694644-augustus-gene-5.5-mRNA-1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" maker-scaffold76size663279-augustus-gene-5.15-mRNA-1 18 Reactome: R-HSA-1482922;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4 "Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Arachidonic acid metabolism" maker-scaffold1size2756217-augustus-gene-12.9-mRNA-1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" maker-scaffold246size295413-augustus-gene-2.6-mRNA-1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" maker-scaffold1251size23169-augustus-gene-0.1-mRNA-1 7 Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-203927 "NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis" maker-scaffold1size2756217-augustus-gene-6.9-mRNA-1 22 MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-7727;MetaCyc: PWY-7606;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-5353;MetaCyc: PWY-6433;MetaCyc: PWY-7049;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601;MetaCyc: PWY-6958;MetaCyc: PWY-7592;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)" maker-scaffold20size1234842-augustus-gene-4.6-mRNA-1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" maker-scaffold389size171159-augustus-gene-0.0-mRNA-1 11 Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418597 "G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events" maker-scaffold441size150191-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" maker-scaffold214size663695-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold913size38062-augustus-gene-0.0-mRNA-1 22 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;KEGG: 00970+6.1.1.7;Reactome: R-HSA-5419276;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-2408557;Reactome: R-HSA-1660662;Reactome: R-HSA-1663150;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Selenocysteine synthesis";"Glycosphingolipid metabolism";"The activation of arylsulfatases";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane" maker-scaffold963size35603-augustus-gene-0.0-mRNA-1 11 MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-7586 "GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" maker-scaffold350size203295-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" maker-scaffold5098size9449-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" maker-scaffold169size953240-augustus-gene-8.23-mRNA-1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" maker-scaffold36size1013817-augustus-gene-4.0-mRNA-1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585 "Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G" maker-scaffold70size694644-augustus-gene-3.0-mRNA-1 7 KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-6969;MetaCyc: PWY-7118;MetaCyc: PWY-7854;MetaCyc: PWY-7295;KEGG: 00630+2.3.3.9 "Pyruvate metabolism";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Chitin degradation to ethanol";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"L-arabinose degradation IV";"Glyoxylate and dicarboxylate metabolism" maker-scaffold371size186194-augustus-gene-0.1-mRNA-1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis" maker-scaffold43size857109-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" maker-scaffold213size330819-augustus-gene-0.0-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold18size2240851-augustus-gene-14.0-mRNA-1 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" maker-scaffold1517size21030-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" maker-scaffold242size299879-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" maker-scaffold367size190875-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold102size543958-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" maker-scaffold3390size5729-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" maker-scaffold31size1053862-augustus-gene-2.10-mRNA-1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" maker-scaffold522size99678-augustus-gene-0.10-mRNA-1 13 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-389357;Reactome: R-HSA-165159;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling";"mTOR signalling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1" maker-scaffold2size2657229-augustus-gene-18.3-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold23size1161859-augustus-gene-0.3-mRNA-1 4 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)" maker-scaffold264size273138-augustus-gene-1.11-mRNA-1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" maker-scaffold189size362018-augustus-gene-1.0-mRNA-1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" maker-scaffold4size1754260-augustus-gene-16.0-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold85size629767-augustus-gene-1.4-mRNA-1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" maker-scaffold80size1421260-augustus-gene-6.0-mRNA-1 3 Reactome: R-HSA-5678771;Reactome: R-HSA-1989781;Reactome: R-HSA-382556 "Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression";"ABC-family proteins mediated transport" maker-scaffold10size1426409-augustus-gene-10.6-mRNA-1 12 MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5871;MetaCyc: PWY-5873 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)" maker-scaffold11size1424826-augustus-gene-2.1-mRNA-1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" augustus-scaffold704size55912-processed-gene-0.0-mRNA-1 79 MetaCyc: PWY-2221;MetaCyc: PWY-5436;MetaCyc: PWY-7346;MetaCyc: PWY-5278;MetaCyc: PWY-1042;MetaCyc: PWY-6587;MetaCyc: PWY-7218;KEGG: 00040+1.1.1.22;KEGG: 00621+1.2.1.10;KEGG: 00620+1.2.1.10;MetaCyc: PWY-5162;KEGG: 00650+1.2.1.10;Reactome: R-HSA-5368286;KEGG: 00450+2.7.7.4;KEGG: 00362+1.2.1.10;MetaCyc: PWY-8004;KEGG: 00360+4.1.3.39;Reactome: R-HSA-6790901;MetaCyc: PWY-5154;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-5419276;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;KEGG: 00362+4.1.3.39;KEGG: 00240+6.3.5.5;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-70263;Reactome: R-HSA-5389840;Reactome: R-HSA-70171;KEGG: 00622+4.1.3.39;Reactome: R-HSA-192823;KEGG: 00010+4.2.1.11;KEGG: 00621+4.1.3.39;KEGG: 00360+1.2.1.10;KEGG: 00250+6.3.5.5;KEGG: 00920+2.7.7.4;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-196843;Reactome: R-HSA-71403;Reactome: R-HSA-156902;MetaCyc: PWY-7124;MetaCyc: PWY-6886;MetaCyc: PWY-6683;Reactome: R-HSA-72702;MetaCyc: PWY-7790;MetaCyc: PWY-7820;MetaCyc: PWY-7180;MetaCyc: PWY-8062;KEGG: 00053+1.1.1.22;Reactome: R-HSA-1268020;MetaCyc: PWY-7003;Reactome: R-HSA-173599;MetaCyc: PWY-7400;Reactome: R-HSA-1236974;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-7791;MetaCyc: PWY-6932;MetaCyc: PWY-5686;Reactome: R-HSA-72764;MetaCyc: PWY-7085;MetaCyc: PWY-5480;MetaCyc: PWY-5723;KEGG: 00520+1.1.1.22;KEGG: 00261+2.7.7.4;KEGG: 00622+1.2.1.10;Reactome: R-HSA-975956;KEGG: 00230+2.7.7.4;MetaCyc: PWY-8060;MetaCyc: PWY-5340 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-threonine degradation IV";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Sulfite oxidation III";"Glycolysis IV (plant cytosol)";"Pyruvate fermentation to ethanol III";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pentose and glucuronate interconversions";"Dioxin degradation";"Pyruvate metabolism";"2-hydroxypenta-2,4-dienoate degradation";"Butanoate metabolism";"Mitochondrial translation initiation";"Selenocompound metabolism";"Benzoate degradation";"Entner-Doudoroff pathway I";"Phenylalanine metabolism";"rRNA modification in the nucleus and cytosol";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Mitochondrial translation termination";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Benzoate degradation";"Pyrimidine metabolism";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Gluconeogenesis";"Mitochondrial translation elongation";"Glycolysis";"Xylene degradation";"Viral mRNA Translation";"Glycolysis / Gluconeogenesis";"Dioxin degradation";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Sulfur metabolism";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Vitamin B2 (riboflavin) metabolism";"Citric acid cycle (TCA cycle)";"Peptide chain elongation";"Ethylene biosynthesis V (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Assimilatory sulfate reduction III";"Ribosomal scanning and start codon recognition";"UMP biosynthesis II";"Teichuronic acid biosynthesis (B. subtilis 168)";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Sulfoacetaldehyde degradation IV";"Ascorbate and aldarate metabolism";"Mitochondrial protein import";"Glycerol degradation to butanol";"Formation of the active cofactor, UDP-glucuronate";"L-arginine biosynthesis IV (archaebacteria)";"ER-Phagosome pathway";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"UMP biosynthesis III";"Selenate reduction";"UMP biosynthesis I";"Eukaryotic Translation Termination";"Triethylamine degradation";"Pyruvate fermentation to ethanol I";"Rubisco shunt";"Amino sugar and nucleotide sugar metabolism";"Monobactam biosynthesis";"Xylene degradation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Purine metabolism";"2-deoxy-D-ribose degradation I";"Sulfate activation for sulfonation" maker-scaffold5size1727520-augustus-gene-15.0-mRNA-1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" maker-scaffold39size909063-augustus-gene-6.0-mRNA-1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" maker-scaffold18size2240851-augustus-gene-2.0-mRNA-1 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)" maker-scaffold13size1375079-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold100size555673-augustus-gene-3.14-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold1size2756217-augustus-gene-26.9-mRNA-1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" maker-scaffold9size1444705-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold552size88858-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" maker-scaffold32size1041436-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" augustus-scaffold1456size19310-processed-gene-0.0-mRNA-1 7 MetaCyc: PWY-6351;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514;MetaCyc: PWY-6352 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis" maker-scaffold4466size21598-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold141size440309-augustus-gene-1.0-mRNA-1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" maker-scaffold13size1375079-augustus-gene-4.16-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold22size1201825-augustus-gene-9.3-mRNA-1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" maker-scaffold285size253012-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" maker-scaffold154size420078-augustus-gene-3.21-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold284size253718-augustus-gene-1.14-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold32size1041436-augustus-gene-2.4-mRNA-1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" maker-scaffold20size1234842-augustus-gene-11.6-mRNA-1 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" maker-scaffold7105size7848-augustus-gene-0.0-mRNA-1 6 MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391;Reactome: R-HSA-446199;Reactome: R-HSA-2426168;Reactome: R-HSA-191273 "Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis" maker-scaffold20size1234842-augustus-gene-3.1-mRNA-1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" maker-scaffold80size1421260-augustus-gene-6.4-mRNA-1 6 Reactome: R-HSA-418597;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005 "G alpha (z) signalling events";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+" maker-scaffold149size424757-augustus-gene-1.0-mRNA-1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034 "Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np" maker-scaffold200size345481-augustus-gene-2.9-mRNA-1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3214815 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"HDACs deacetylate histones" maker-scaffold229size310297-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" maker-scaffold223size319359-augustus-gene-2.2-mRNA-1 18 Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243 "Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery" maker-scaffold54size1273868-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" maker-scaffold361size197669-augustus-gene-1.2-mRNA-1 4 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-425561 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination";"Sodium/Calcium exchangers" maker-scaffold110size515606-augustus-gene-3.8-mRNA-1 24 Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-5621575;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610780;Reactome: R-HSA-8853659;KEGG: 04150+2.7.11.11;Reactome: R-HSA-111931;Reactome: R-HSA-9010642;Reactome: R-HSA-5610783;Reactome: R-HSA-180024;Reactome: R-HSA-8963896;Reactome: R-HSA-422356;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-4420097;Reactome: R-HSA-9634600 "Triglyceride catabolism";"Rap1 signalling";"CD209 (DC-SIGN) signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI1 by the proteasome";"RET signaling";"mTOR signaling pathway";"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"Degradation of GLI2 by the proteasome";"DARPP-32 events";"HDL assembly";"Regulation of insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"VEGFA-VEGFR2 Pathway";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" maker-scaffold2size2657229-augustus-gene-14.1-mRNA-1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" maker-scaffold19size1242042-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" maker-scaffold50size801739-augustus-gene-7.8-mRNA-1 3 KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" maker-scaffold293size245513-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5689603 "UCH proteinases" maker-scaffold2size2657229-augustus-gene-25.3-mRNA-1 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" maker-scaffold14size1670589-augustus-gene-15.23-mRNA-1 4 MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation" maker-scaffold58size769326-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold72size687670-augustus-gene-4.0-mRNA-1 7 MetaCyc: PWY-7234;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2 "Inosine-5'-phosphate biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism" maker-scaffold55size783029-augustus-gene-1.0-mRNA-1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes" maker-scaffold169size953240-augustus-gene-8.15-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold90size602833-augustus-gene-0.1-mRNA-1 6 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation" maker-scaffold1676size22910-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" maker-scaffold278size260935-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-1632852 "Macroautophagy" maker-scaffold36size1013817-augustus-gene-9.2-mRNA-1 10 MetaCyc: PWY-6613;MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201;MetaCyc: PWY-7909;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate" maker-scaffold31size1053862-augustus-gene-2.14-mRNA-1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" maker-scaffold28size1079920-augustus-gene-1.7-mRNA-1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" maker-scaffold51size814512-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold248size292329-augustus-gene-1.19-mRNA-1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942 "Translesion synthesis by POLI";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)" maker-scaffold6size1916839-augustus-gene-13.0-mRNA-1 4 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold38size924328-augustus-gene-8.2-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" maker-scaffold160size414734-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" maker-scaffold38size924328-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold148size437419-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold25size1130848-augustus-gene-10.2-mRNA-1 3 Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway" maker-scaffold12046size14431-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-5620922;Reactome: R-HSA-6782315 "BBSome-mediated cargo-targeting to cilium";"tRNA modification in the nucleus and cytosol" maker-scaffold4size1754260-augustus-gene-6.2-mRNA-1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" augustus-scaffold2539size9219-processed-gene-0.0-mRNA-1 6 MetaCyc: PWY-101;Reactome: R-HSA-6782315;Reactome: R-HSA-5362517;KEGG: 00195+1.18.1.2;Reactome: R-HSA-5657655;Reactome: R-HSA-204174 "Photosynthesis light reactions";"tRNA modification in the nucleus and cytosol";"Signaling by Retinoic Acid";"Photosynthesis";"MGMT-mediated DNA damage reversal";"Regulation of pyruvate dehydrogenase (PDH) complex" maker-scaffold6size1916839-augustus-gene-18.3-mRNA-1 10 Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6554;MetaCyc: PWY-6372 "Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" maker-scaffold122size477764-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold1366size20909-augustus-gene-0.0-mRNA-1 10 Reactome: R-HSA-4717374;MetaCyc: PWY-7661;MetaCyc: PWY-7922;Reactome: R-HSA-162699;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360;MetaCyc: PWY-7921;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;Reactome: R-HSA-913709 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein N-glycosylation (Haloferax volcanii)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation I (yeast)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation of mucins" maker-scaffold1744size15393-augustus-gene-0.0-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" maker-scaffold1size2756217-augustus-gene-7.8-mRNA-1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" maker-scaffold1size2756217-augustus-gene-25.1-mRNA-1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases" augustus-scaffold1332size21382-processed-gene-0.0-mRNA-1 3 Reactome: R-HSA-6791226;Reactome: R-HSA-3371453;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of HSF1-mediated heat shock response";"rRNA modification in the nucleus and cytosol" maker-scaffold99size561911-augustus-gene-2.2-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold18size2240851-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" maker-scaffold48size811354-augustus-gene-7.9-mRNA-1 5 Reactome: R-HSA-5083635;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination";"O-glycosylation of TSR domain-containing proteins" maker-scaffold13size1375079-augustus-gene-5.4-mRNA-1 8 Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.67;Reactome: R-HSA-2022377;MetaCyc: PWY-6351;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.67 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Metabolism of Angiotensinogen to Angiotensins";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system" maker-scaffold255size285696-augustus-gene-1.5-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold2716size8427-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" maker-scaffold13size1375079-augustus-gene-4.10-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold353size206126-augustus-gene-0.4-mRNA-1 5 MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)" maker-scaffold22size1201825-augustus-gene-9.5-mRNA-1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" maker-scaffold65size703589-augustus-gene-6.11-mRNA-1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" maker-scaffold318size381727-augustus-gene-2.6-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold15size1261043-augustus-gene-11.5-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression" maker-scaffold1098size28945-augustus-gene-0.2-mRNA-1 6 MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;Reactome: R-HSA-70221 "Glycogen degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)" maker-scaffold20size1234842-augustus-gene-6.0-mRNA-1 29 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-73772;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-75953 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Promoter Escape";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation" maker-scaffold12071size7481-augustus-gene-0.2-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold58size769326-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold2size2657229-augustus-gene-25.30-mRNA-1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1" maker-scaffold20size1234842-augustus-gene-4.9-mRNA-1 57 Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761 "Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Neutrophil degranulation";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Orc1 removal from chromatin";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"ER-Phagosome pathway";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling" maker-scaffold5size1727520-augustus-gene-13.4-mRNA-1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" maker-scaffold131size455331-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold378size180454-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" maker-scaffold67size700687-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" maker-scaffold53size789746-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" maker-scaffold3size2782310-augustus-gene-21.0-mRNA-1 3 Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" maker-scaffold5size1727520-augustus-gene-1.3-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold2579size9016-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" maker-scaffold17size1249603-augustus-gene-11.10-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold55246size7190-augustus-gene-0.1-mRNA-1 9 MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842 "4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II" maker-scaffold352size202783-augustus-gene-1.6-mRNA-1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" maker-scaffold77size662763-augustus-gene-5.7-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold6size1916839-augustus-gene-8.5-mRNA-1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" maker-scaffold89size602897-augustus-gene-5.13-mRNA-1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" maker-scaffold48size811354-augustus-gene-4.8-mRNA-1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" maker-scaffold884size39766-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" maker-scaffold24size1136029-augustus-gene-9.2-mRNA-1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" maker-scaffold4785size3257-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" maker-scaffold1640size16902-augustus-gene-0.0-mRNA-1 6 KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series" maker-scaffold9size1444705-augustus-gene-12.5-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold71size686415-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-173623;Reactome: R-HSA-166663;Reactome: R-HSA-977606 "Classical antibody-mediated complement activation";"Initial triggering of complement";"Regulation of Complement cascade" maker-scaffold2size2657229-augustus-gene-25.15-mRNA-1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" maker-scaffold50size801739-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" maker-scaffold75size670735-augustus-gene-5.10-mRNA-1 4 Reactome: R-HSA-8866910;Reactome: R-HSA-3232118;Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "TFAP2 (AP-2) family regulates transcription of growth factors and their receptors";"SUMOylation of transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" maker-scaffold84size638750-augustus-gene-5.13-mRNA-1 32 Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-77075;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-72203 "Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA" maker-scaffold409size152889-augustus-gene-0.3-mRNA-1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis" maker-scaffold1size2756217-augustus-gene-9.3-mRNA-1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" maker-scaffold1313size21806-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-381426;Reactome: R-HSA-5662702;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Melanin biosynthesis";"VLDLR internalisation and degradation";"LDL clearance";"Post-translational protein phosphorylation" maker-scaffold4size1754260-augustus-gene-13.7-mRNA-1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" maker-scaffold351size203122-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold29size1057726-augustus-gene-3.1-mRNA-1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" maker-scaffold154size420078-augustus-gene-3.5-mRNA-1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" maker-scaffold36size1013817-augustus-gene-9.1-mRNA-1 7 MetaCyc: PWY-7790;KEGG: 00230+3.5.2.5;MetaCyc: PWY-5697;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5698;MetaCyc: PWY-5686;MetaCyc: PWY-7791 "UMP biosynthesis II";"Purine metabolism";"Allantoin degradation to ureidoglycolate I (urea producing)";"Pyrimidine metabolism";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"UMP biosynthesis I";"UMP biosynthesis III" maker-scaffold153size420471-augustus-gene-3.0-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold254size288410-augustus-gene-1.6-mRNA-1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" maker-scaffold3size2782310-augustus-gene-24.0-mRNA-1 8 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold80size1421260-augustus-gene-4.5-mRNA-1 12 Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" maker-scaffold73size681921-augustus-gene-4.2-mRNA-1 14 Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis" maker-scaffold335size212668-augustus-gene-1.13-mRNA-1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" maker-scaffold876size40673-augustus-gene-0.2-mRNA-1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52 "Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis" maker-scaffold4926size20599-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" maker-scaffold1370size20743-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-913709;KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "O-linked glycosylation of mucins";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" maker-scaffold293size245513-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold49size896674-augustus-gene-6.7-mRNA-1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3 "Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism" maker-scaffold170size397864-augustus-gene-0.2-mRNA-1 18 Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" maker-scaffold580size82153-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Gap junction degradation";"Cargo recognition for clathrin-mediated endocytosis" maker-scaffold45size832949-augustus-gene-7.8-mRNA-1 28 Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-6798163;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4085377 "HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Choline catabolism";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins" maker-scaffold163size408523-augustus-gene-0.1-mRNA-1 7 Reactome: R-HSA-9020265;Reactome: R-HSA-2142691;Reactome: R-HSA-9018896;Reactome: R-HSA-9018681;Reactome: R-HSA-6798695;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661 "Biosynthesis of aspirin-triggered D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of protectins";"Neutrophil degranulation";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins" maker-scaffold18size2240851-augustus-gene-12.4-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold135size449244-augustus-gene-3.2-mRNA-1 6 Reactome: R-HSA-9029558;Reactome: R-HSA-9640463;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Wax biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression" maker-scaffold1588size17117-augustus-gene-0.0-mRNA-1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" maker-scaffold209size335547-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" maker-scaffold87size608750-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" maker-scaffold7683size8306-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold59size767954-augustus-gene-4.6-mRNA-1 12 Reactome: R-HSA-9013700;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells" maker-scaffold5size1727520-augustus-gene-12.1-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold31size1053862-augustus-gene-9.0-mRNA-1 3 KEGG: 00511+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45 "Other glycan degradation";"Glycosphingolipid metabolism";"Sphingolipid metabolism" maker-scaffold6size1916839-augustus-gene-13.2-mRNA-1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" maker-scaffold150size559075-augustus-gene-4.0-mRNA-1 4 Reactome: R-HSA-1362409;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581 "Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis" maker-scaffold470size124269-augustus-gene-0.8-mRNA-1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-1268020 "Processing of SMDT1";"Mitochondrial protein import" maker-scaffold254size288410-augustus-gene-1.18-mRNA-1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state" maker-scaffold23size1161859-augustus-gene-10.12-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold23size1161859-augustus-gene-10.10-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold24size1136029-augustus-gene-8.4-mRNA-1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" maker-scaffold243size299871-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" maker-scaffold2size2657229-augustus-gene-0.2-mRNA-1 4 Reactome: R-HSA-3359478;Reactome: R-HSA-196741;Reactome: R-HSA-71032;Reactome: R-HSA-3359475 "Defective MUT causes methylmalonic aciduria mut type";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Propionyl-CoA catabolism";"Defective MMAA causes methylmalonic aciduria type cblA" maker-scaffold73size681921-augustus-gene-3.0-mRNA-1 7 MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism" maker-scaffold20size1234842-augustus-gene-11.1-mRNA-1 4 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions" maker-scaffold2size2657229-augustus-gene-4.5-mRNA-1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" maker-scaffold6size1916839-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" maker-scaffold1size2756217-augustus-gene-6.3-mRNA-1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" maker-scaffold216size329809-augustus-gene-0.1-mRNA-1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" maker-scaffold21size1197050-augustus-gene-8.9-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold18size2240851-augustus-gene-3.5-mRNA-1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" maker-scaffold948size36209-augustus-gene-0.0-mRNA-1 5 MetaCyc: PWY-5067;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11 "Glycogen biosynthesis II (from UDP-D-Glucose)";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Glycogen synthesis";"Starch and sucrose metabolism" maker-scaffold1size2756217-augustus-gene-11.4-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold80size1421260-augustus-gene-10.1-mRNA-1 9 Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-438066 "Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation" maker-scaffold8size1945031-augustus-gene-11.7-mRNA-1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" maker-scaffold34size991984-augustus-gene-3.17-mRNA-1 5 Reactome: R-HSA-194840;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "Rho GTPase cycle";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I" maker-scaffold228size313446-augustus-gene-2.8-mRNA-1 14 Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-2979096 "Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NOTCH2 Activation and Transmission of Signal to the Nucleus" maker-scaffold382size176025-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" maker-scaffold271size267669-augustus-gene-1.13-mRNA-1 6 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-9640463;Reactome: R-HSA-2426168;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Wax biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis" maker-scaffold122size477764-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" maker-scaffold5size1727520-augustus-gene-8.14-mRNA-1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "Neutrophil degranulation";"Nephrin family interactions";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" maker-scaffold20size1234842-augustus-gene-10.1-mRNA-1 8 MetaCyc: PWY-7187;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.9;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" maker-scaffold1size2756217-augustus-gene-5.0-mRNA-1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-432040 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins" maker-scaffold281size259073-augustus-gene-1.11-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" augustus-scaffold5965size2822-processed-gene-0.1-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold47size1319914-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" maker-scaffold76size663279-augustus-gene-5.4-mRNA-1 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" augustus-scaffold657size63075-processed-gene-0.1-mRNA-1 57 Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-4608870;Reactome: R-HSA-350562 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"G2/M Checkpoints";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Neutrophil degranulation";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)" maker-scaffold72size687670-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold121size481755-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold227size314013-augustus-gene-1.5-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold8587size14839-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" maker-scaffold44size860316-augustus-gene-5.2-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold312size267838-augustus-gene-0.1-mRNA-1 5 KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" maker-scaffold559size87523-augustus-gene-0.2-mRNA-1 10 KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-6855;Reactome: R-HSA-5675221;Reactome: R-HSA-8939211;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Chitin degradation I (archaea)";"Negative regulation of MAPK pathway";"ESR-mediated signaling";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" maker-scaffold22size1201825-augustus-gene-4.23-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold1205size24461-augustus-gene-0.0-mRNA-1 5 MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;MetaCyc: PWY-5188 "Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" maker-scaffold1168size25805-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-70921;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5030;MetaCyc: PWY-5028 "Histidine catabolism";"Histidine metabolism";"L-histidine degradation III";"L-histidine degradation II" maker-scaffold3655size7574-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-71403;Reactome: R-HSA-5628897;Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"TP53 Regulates Metabolic Genes";"Mitochondrial protein import";"Respiratory electron transport" maker-scaffold21size1197050-augustus-gene-5.2-mRNA-1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" maker-scaffold157size419459-augustus-gene-3.17-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold608size111783-augustus-gene-0.2-mRNA-1 26 Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-389977;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins" maker-scaffold14size1670589-augustus-gene-0.4-mRNA-1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-381676;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509 "Ion homeostasis";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling" maker-scaffold22size1201825-augustus-gene-3.1-mRNA-1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6 "D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism" maker-scaffold4509size3448-augustus-gene-0.0-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold10size1426409-augustus-gene-10.0-mRNA-1 2 Reactome: R-HSA-3772470;Reactome: R-HSA-201681 "Negative regulation of TCF-dependent signaling by WNT ligand antagonists";"TCF dependent signaling in response to WNT" maker-scaffold19size1242042-augustus-gene-11.10-mRNA-1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" maker-scaffold10size1426409-augustus-gene-9.8-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" maker-scaffold31109size7281-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold342size295439-augustus-gene-1.7-mRNA-1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" maker-scaffold19size1242042-augustus-gene-11.8-mRNA-1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081 "Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling" maker-scaffold9size1444705-augustus-gene-8.1-mRNA-1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" maker-scaffold231size308180-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" maker-scaffold16size1255579-augustus-gene-11.3-mRNA-1 26 Reactome: R-HSA-5685942;Reactome: R-HSA-4615885;Reactome: R-HSA-5696397;Reactome: R-HSA-8866654;Reactome: R-HSA-5358565;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-69205;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-174414 "HDR through Homologous Recombination (HRR)";"SUMOylation of DNA replication proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"G1/S-Specific Transcription";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Processive synthesis on the C-strand of the telomere" maker-scaffold1size2756217-augustus-gene-26.7-mRNA-1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold680size59312-augustus-gene-0.2-mRNA-1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" maker-scaffold507size105377-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" maker-scaffold246size295413-augustus-gene-1.1-mRNA-1 10 Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-163680 "Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity" maker-scaffold45size832949-augustus-gene-7.16-mRNA-1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" maker-scaffold28size1079920-augustus-gene-0.4-mRNA-1 7 Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-69205 "Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription" maker-scaffold234size306624-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold238size302402-augustus-gene-1.1-mRNA-1 4 Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-166058 "Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" maker-scaffold157size419459-augustus-gene-3.16-mRNA-1 6 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-9640463;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Wax biosynthesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)" maker-scaffold21size1197050-augustus-gene-6.2-mRNA-1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" maker-scaffold229size310297-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" maker-scaffold145size712617-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" maker-scaffold1size2756217-augustus-gene-25.5-mRNA-1 7 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" maker-scaffold514size105244-augustus-gene-0.6-mRNA-1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" augustus-scaffold1273size22681-processed-gene-0.0-mRNA-1 57 Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858 "Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity" maker-scaffold54size1273868-augustus-gene-8.0-mRNA-1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" maker-scaffold14size1670589-augustus-gene-9.5-mRNA-1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" maker-scaffold92size586643-augustus-gene-4.25-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold1310size21844-augustus-gene-0.2-mRNA-1 13 MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;Reactome: R-HSA-140837;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;Reactome: R-HSA-70263;Reactome: R-HSA-111471;Reactome: R-HSA-70171;MetaCyc: PWY-8004;Reactome: R-HSA-9645722 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Intrinsic Pathway of Fibrin Clot Formation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Apoptotic factor-mediated response";"Glycolysis";"Entner-Doudoroff pathway I";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" maker-scaffold59size767954-augustus-gene-6.12-mRNA-1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749 "ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs" maker-scaffold193size358747-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold14906size7563-augustus-gene-0.0-mRNA-1 9 Reactome: R-HSA-110331;Reactome: R-HSA-9608290;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9608287 "Cleavage of the damaged purine";"Defective MUTYH substrate processing";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Defective MUTYH substrate binding" maker-scaffold28size1079920-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold526size170922-augustus-gene-0.1-mRNA-1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-9636467 "ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Blockage of phagosome acidification" augustus-scaffold1031size31644-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-6791226 "VLDLR internalisation and degradation";"LDL clearance";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold21size1197050-augustus-gene-7.5-mRNA-1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" maker-scaffold84size638750-augustus-gene-4.13-mRNA-1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" maker-scaffold78size655360-augustus-gene-5.7-mRNA-1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" maker-scaffold652size64092-augustus-gene-0.2-mRNA-1 27 Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-936837;Reactome: R-HSA-8866907;Reactome: R-HSA-1234158;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575 "TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"Ion transport by P-type ATPases";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression by Hypoxia-inducible Factor";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"PPARA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling" maker-scaffold59size767954-augustus-gene-4.0-mRNA-1 2 Reactome: R-HSA-4551638;Reactome: R-HSA-8953750 "SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6" maker-scaffold169size953240-augustus-gene-8.10-mRNA-1 26 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-389960 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC" maker-scaffold2288size13423-augustus-gene-0.0-mRNA-1 8 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" augustus-scaffold2018size12516-processed-gene-0.0-mRNA-1 6 MetaCyc: PWY-7790;MetaCyc: PWY-7791;Reactome: R-HSA-500753;MetaCyc: PWY-5686;Reactome: R-HSA-6798695;KEGG: 00240+4.1.1.23 "UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Neutrophil degranulation";"Pyrimidine metabolism" maker-scaffold470size124269-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" maker-scaffold5size1727520-augustus-gene-14.1-mRNA-1 8 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269 "PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Signaling by Hippo" maker-scaffold72size687670-augustus-gene-3.7-mRNA-1 13 MetaCyc: PWY-7226;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00983+1.17.4.1 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Drug metabolism - other enzymes" maker-scaffold52size909272-augustus-gene-3.0-mRNA-1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" maker-scaffold251size291382-augustus-gene-1.4-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold128size459976-augustus-gene-2.2-mRNA-1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" maker-scaffold11size1424826-augustus-gene-7.5-mRNA-1 9 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-425561;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-418359;Reactome: R-HSA-380994;Reactome: R-HSA-5578775 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Sodium/Calcium exchangers";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Reduction of cytosolic Ca++ levels";"ATF4 activates genes in response to endoplasmic reticulum stress";"Ion homeostasis" maker-scaffold668size61261-augustus-gene-0.0-mRNA-1 7 Reactome: R-HSA-196780;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6277;Reactome: R-HSA-73817 "Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" maker-scaffold35size976498-augustus-gene-2.0-mRNA-1 6 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"ChREBP activates metabolic gene expression" maker-scaffold284size253718-augustus-gene-1.15-mRNA-1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" maker-scaffold71size686415-augustus-gene-5.0-mRNA-1 9 Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-400253 "Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock" augustus-scaffold1487size18798-processed-gene-0.0-mRNA-1 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" augustus-scaffold604size77144-processed-gene-0.1-mRNA-1 6 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5419276;Reactome: R-HSA-6798695 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitochondrial translation termination";"Neutrophil degranulation" maker-scaffold402size240807-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold8620size7975-augustus-gene-0.1-mRNA-1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-68952 "HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"DNA replication initiation" maker-scaffold21size1197050-augustus-gene-10.3-mRNA-1 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" maker-scaffold65size703589-augustus-gene-5.2-mRNA-1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" maker-scaffold99size561911-augustus-gene-0.3-mRNA-1 29 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-75953 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation" maker-scaffold5size1727520-augustus-gene-4.11-mRNA-1 1 Reactome: R-HSA-71288 "Creatine metabolism" maker-scaffold337size211899-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" maker-scaffold19size1242042-augustus-gene-0.2-mRNA-1 7 MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606 "Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" augustus-scaffold1424size19806-processed-gene-0.1-mRNA-1 4 Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-156581;Reactome: R-HSA-6790901 "tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation";"rRNA modification in the nucleus and cytosol" maker-scaffold5936size9736-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold20size1234842-augustus-gene-5.0-mRNA-1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" maker-scaffold11801size7806-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" maker-scaffold8size1945031-augustus-gene-4.1-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold1size2756217-augustus-gene-12.6-mRNA-1 16 Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902 "Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation" maker-scaffold73size681921-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" maker-scaffold21size1197050-augustus-gene-3.5-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold26size1667613-augustus-gene-3.1-mRNA-1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" maker-scaffold34size991984-augustus-gene-3.12-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" augustus-scaffold1085size29322-processed-gene-0.1-mRNA-1 12 MetaCyc: PWY-7560;MetaCyc: PWY-4381;Reactome: R-HSA-3371599;Reactome: R-HSA-110357;KEGG: 00970+6.1.1.22;MetaCyc: PWY-6892;MetaCyc: PWY-6891;Reactome: R-HSA-196780;KEGG: 00750+1.1.1.262;KEGG: 00730+2.2.1.7;KEGG: 00061+2.3.1.180;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Fatty acid biosynthesis initiation (bacteria and plants)";"Defective HLCS causes multiple carboxylase deficiency";"Displacement of DNA glycosylase by APEX1";"Aminoacyl-tRNA biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Biotin transport and metabolism";"Vitamin B6 metabolism";"Thiamine metabolism";"Fatty acid biosynthesis";"Terpenoid backbone biosynthesis" maker-scaffold36size1013817-augustus-gene-9.5-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold320size221394-augustus-gene-1.10-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold169size953240-augustus-gene-5.14-mRNA-1 7 MetaCyc: PWY-7822;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;KEGG: 04658+3.1.3.16;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Th1 and Th2 cell differentiation";"Chitin degradation II (Vibrio)" maker-scaffold59size767954-augustus-gene-3.12-mRNA-1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" augustus-scaffold5047size3128-processed-gene-0.1-mRNA-1 30 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-2564830;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cytosolic iron-sulfur cluster assembly";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" maker-scaffold2872size8492-augustus-gene-0.1-mRNA-1 22 Reactome: R-HSA-9010553;MetaCyc: PWY-7286;Reactome: R-HSA-72764;Reactome: R-HSA-156902;MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-8868766;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6787450;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-6785470 "Regulation of expression of SLITs and ROBOs";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA processing in the mitochondrion";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"tRNA modification in the mitochondrion";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"tRNA processing in the mitochondrion" maker-scaffold110size515606-augustus-gene-3.14-mRNA-1 1 Reactome: R-HSA-3295583 "TRP channels" maker-scaffold231size308180-augustus-gene-2.4-mRNA-1 14 MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7589;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51 "CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Palmitoleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism" augustus-scaffold28989size7296-processed-gene-0.1-mRNA-1 7 MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5 "L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism" maker-scaffold16size1255579-augustus-gene-5.5-mRNA-1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" maker-scaffold8size1945031-augustus-gene-5.0-mRNA-1 5 KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;MetaCyc: PWY-7782 "Ether lipid metabolism";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Plasmalogen biosynthesis" maker-scaffold3size2782310-augustus-gene-14.2-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold20size1234842-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" maker-scaffold12size1412574-augustus-gene-8.2-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold12size1412574-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" maker-scaffold14size1670589-augustus-gene-9.1-mRNA-1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" maker-scaffold1size2756217-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" maker-scaffold9size1444705-augustus-gene-11.4-mRNA-1 5 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-8866654 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins" maker-scaffold42size1661181-augustus-gene-12.3-mRNA-1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" maker-scaffold23size1161859-augustus-gene-5.8-mRNA-1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553 "Non-integrin membrane-ECM interactions";"ECM proteoglycans";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs" maker-scaffold30size1054049-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" maker-scaffold1493size18652-augustus-gene-0.1-mRNA-1 6 KEGG: 00240+6.3.4.2;Reactome: R-HSA-8949664;MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943;MetaCyc: PWY-7177 "Pyrimidine metabolism";"Processing of SMDT1";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II" maker-scaffold238size302402-augustus-gene-2.5-mRNA-1 17 Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693548;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-1834949;Reactome: R-HSA-69473 "HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Sensing of DNA Double Strand Breaks";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Cytosolic sensors of pathogen-associated DNA";"G2/M DNA damage checkpoint" maker-scaffold121size481755-augustus-gene-0.1-mRNA-1 19 MetaCyc: PWY-5913;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6638;MetaCyc: PWY-7383;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;Reactome: R-HSA-901032;KEGG: 00360+2.6.1.1;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1 "Partial TCA cycle (obligate autotrophs)";"Arginine biosynthesis";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"Arginine and proline metabolism";"(R)-cysteate degradation";"Alanine, aspartate and glutamate metabolism";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"ER Quality Control Compartment (ERQC)";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis" maker-scaffold3210size13013-augustus-gene-0.1-mRNA-1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" maker-scaffold72size687670-augustus-gene-3.9-mRNA-1 5 Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "TBC/RABGAPs";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" maker-scaffold1806size14640-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" maker-scaffold205size344292-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" maker-scaffold1061size30239-augustus-gene-0.0-mRNA-1 5 KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841 "Folate biosynthesis";"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)" maker-scaffold27size1200182-augustus-gene-10.1-mRNA-1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" maker-scaffold12size1412574-augustus-gene-11.3-mRNA-1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" maker-scaffold190size360960-augustus-gene-0.2-mRNA-1 13 MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7659;MetaCyc: PWY-7410;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1 "Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis" maker-scaffold53size789746-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-375276 "Peptide ligand-binding receptors" maker-scaffold8size1945031-augustus-gene-6.3-mRNA-1 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" maker-scaffold12size1412574-augustus-gene-13.14-mRNA-1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" maker-scaffold336size212269-augustus-gene-0.0-mRNA-1 3 MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" maker-scaffold16size1255579-augustus-gene-4.19-mRNA-1 9 Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-76042 "HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance" maker-scaffold5size1727520-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" maker-scaffold1size2756217-augustus-gene-23.5-mRNA-1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" maker-scaffold145size712617-augustus-gene-5.0-mRNA-1 34 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9639288;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-159236 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Amino acids regulate mTORC1";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold35size976498-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" maker-scaffold579size82347-augustus-gene-0.0-mRNA-1 14 KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-8052;Reactome: R-HSA-1483191 "Glycerophospholipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Sphingolipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC" maker-scaffold725size53754-augustus-gene-0.2-mRNA-1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-162791 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Attachment of GPI anchor to uPAR" maker-scaffold254size288410-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold2size2657229-augustus-gene-8.8-mRNA-1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination" maker-scaffold12size1412574-augustus-gene-2.8-mRNA-1 6 MetaCyc: PWY-7900;MetaCyc: PWY-622;MetaCyc: PWY-5067;Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781 "Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)" maker-scaffold264size273138-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold359size198927-augustus-gene-1.5-mRNA-1 1 KEGG: 00970+6.1.1.5 "Aminoacyl-tRNA biosynthesis" maker-scaffold7258size8081-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold232size307321-augustus-gene-1.1-mRNA-1 17 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;MetaCyc: PWY-5642;Reactome: R-HSA-70895;Reactome: R-HSA-2408557;KEGG: 00280+1.2.1.27;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;KEGG: 00640+1.2.1.27;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Selenocysteine synthesis";"Valine, leucine and isoleucine degradation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Propanoate metabolism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" maker-scaffold93size585897-augustus-gene-4.7-mRNA-1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" maker-scaffold8231size7640-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" maker-scaffold15size1261043-augustus-gene-6.1-mRNA-1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" augustus-scaffold95size722721-processed-gene-6.0-mRNA-1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" augustus-scaffold2119size11571-processed-gene-0.0-mRNA-1 56 Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895 "Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis" maker-scaffold9size1444705-augustus-gene-11.3-mRNA-1 3 Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway" maker-scaffold13size1375079-augustus-gene-9.0-mRNA-1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" maker-scaffold708size55612-augustus-gene-0.2-mRNA-1 4 MetaCyc: PWY-5041;Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism" maker-scaffold7748size1593-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold42size1661181-augustus-gene-3.7-mRNA-1 18 MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" maker-scaffold491size112383-augustus-gene-0.1-mRNA-1 14 Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426496 "Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs" maker-scaffold261size276640-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" maker-scaffold531size95887-augustus-gene-0.3-mRNA-1 57 Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783 "Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome" maker-scaffold1size2756217-augustus-gene-25.8-mRNA-1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" maker-scaffold830size44237-augustus-gene-0.2-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold235size305606-augustus-gene-2.1-mRNA-1 3 Reactome: R-HSA-204005;Reactome: R-HSA-5694530;Reactome: R-HSA-948021 "COPII-mediated vesicle transport";"Cargo concentration in the ER";"Transport to the Golgi and subsequent modification" maker-scaffold2size2657229-augustus-gene-0.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold302size236263-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold143size433092-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold238size302402-augustus-gene-2.9-mRNA-1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" maker-scaffold263size273711-augustus-gene-1.1-mRNA-1 25 Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-380270;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Recruitment of mitotic centrosome proteins and complexes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids" maker-scaffold266size269306-augustus-gene-1.9-mRNA-1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" maker-scaffold23size1161859-augustus-gene-5.9-mRNA-1 2 Reactome: R-HSA-111457;Reactome: R-HSA-111469 "Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response" maker-scaffold4size1754260-augustus-gene-7.5-mRNA-1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" maker-scaffold34size991984-augustus-gene-8.5-mRNA-1 3 Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" maker-scaffold1357size20966-augustus-gene-0.2-mRNA-1 7 KEGG: 00790+2.10.1.1;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-947581 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Respiratory electron transport";"Complex I biogenesis";"Molybdenum cofactor biosynthesis" maker-scaffold3size2782310-augustus-gene-4.24-mRNA-1 6 Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181429 "Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" maker-scaffold86size613819-augustus-gene-4.6-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold21size1197050-augustus-gene-9.0-mRNA-1 5 Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" maker-scaffold122size477764-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" maker-scaffold10size1426409-augustus-gene-3.2-mRNA-1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159 "Neutrophil degranulation";"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling" maker-scaffold78size655360-augustus-gene-2.1-mRNA-1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" maker-scaffold1400size20171-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983168;KEGG: 00970+6.1.1.9 "Antigen processing: Ubiquitination & Proteasome degradation";"Aminoacyl-tRNA biosynthesis" maker-scaffold8size1945031-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" maker-scaffold181size378167-augustus-gene-1.1-mRNA-1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" maker-scaffold45size832949-augustus-gene-4.20-mRNA-1 19 Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-381426 "Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL remodeling";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"VLDL assembly";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Chylomicron assembly";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" maker-scaffold5size1727520-augustus-gene-4.9-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold158size418592-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold243size299871-augustus-gene-0.2-mRNA-1 5 Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" maker-scaffold260size277064-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" maker-scaffold6size1916839-augustus-gene-8.2-mRNA-1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold89size602897-augustus-gene-5.20-mRNA-1 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565;Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"ESR-mediated signaling";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold410size152082-augustus-gene-0.3-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" maker-scaffold41size887692-augustus-gene-1.1-mRNA-1 7 KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;KEGG: 00670+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-6614;MetaCyc: PWY-3841;Reactome: R-HSA-196757 "Folate biosynthesis";"G1/S-Specific Transcription";"One carbon pool by folate";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"Metabolism of folate and pterines" maker-scaffold2171size14399-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold37size976698-augustus-gene-1.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold28size1079920-augustus-gene-8.0-mRNA-1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" maker-scaffold24size1136029-augustus-gene-7.0-mRNA-1 24 Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-456926;Reactome: R-HSA-8964616;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-4086398 "ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through CDC42";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"Ca2+ pathway" maker-scaffold37size976698-augustus-gene-6.3-mRNA-1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113 "Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1" maker-scaffold59size767954-augustus-gene-3.9-mRNA-1 10 Reactome: R-HSA-3899300;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538 "SUMOylation of transcription cofactors";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA" maker-scaffold20size1234842-augustus-gene-4.4-mRNA-1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" maker-scaffold16size1255579-augustus-gene-10.0-mRNA-1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold1923size13368-augustus-gene-0.1-mRNA-1 6 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis" maker-scaffold198size347650-augustus-gene-2.2-mRNA-1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" maker-scaffold192size359585-augustus-gene-1.0-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold20size1234842-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" maker-scaffold2454size17199-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" maker-scaffold138size440403-augustus-gene-3.5-mRNA-1 5 Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Protein ubiquitination";"Ub-specific processing proteases" maker-scaffold307size231700-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" maker-scaffold45size832949-augustus-gene-1.0-mRNA-1 3 MetaCyc: PWY-1269;Reactome: R-HSA-4085001;KEGG: 00540+2.7.7.38 "CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Sialic acid metabolism";"Lipopolysaccharide biosynthesis" maker-scaffold701size56601-augustus-gene-0.0-mRNA-1 13 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" maker-scaffold136size447168-augustus-gene-3.5-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold36size1013817-augustus-gene-4.10-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold82size640827-augustus-gene-5.0-mRNA-1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold72size687670-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6783984 "Glycine degradation" maker-scaffold9size1444705-augustus-gene-4.21-mRNA-1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" maker-scaffold185size368400-augustus-gene-2.8-mRNA-1 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" maker-scaffold235size305606-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" maker-scaffold145size712617-augustus-gene-3.6-mRNA-1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" maker-scaffold19size1242042-augustus-gene-8.2-mRNA-1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" maker-scaffold2size2657229-augustus-gene-25.4-mRNA-1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" maker-scaffold19size1242042-augustus-gene-6.3-mRNA-1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" augustus-scaffold594size79231-processed-gene-0.0-mRNA-1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;MetaCyc: PWY-6167;MetaCyc: PWY-6168;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;KEGG: 00740+4.1.99.12;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Flavin biosynthesis II (archaea)";"Flavin biosynthesis III (fungi)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Riboflavin metabolism";"Peptide chain elongation" maker-scaffold218size326752-augustus-gene-2.11-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" maker-scaffold77size662763-augustus-gene-5.26-mRNA-1 6 Reactome: R-HSA-6785470;MetaCyc: PWY-7285;Reactome: R-HSA-8868766;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6787450 "tRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the mitochondrion" maker-scaffold71size686415-augustus-gene-5.10-mRNA-1 5 Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936440 "TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulators of DDX58/IFIH1 signaling" maker-scaffold652size64092-augustus-gene-0.3-mRNA-1 18 KEGG: 00250+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;MetaCyc: PWY-6638 "Alanine, aspartate and glutamate metabolism";"(R)-cysteate degradation";"Arginine and proline metabolism";"Carbon fixation in photosynthetic organisms";"Arginine biosynthesis";"Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Coenzyme M biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III" maker-scaffold11size1424826-augustus-gene-9.6-mRNA-1 11 Reactome: R-HSA-168138;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.137;Reactome: R-HSA-5668599;MetaCyc: PWY-6352;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-1660517 "Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the late endosome membrane" maker-scaffold45size832949-augustus-gene-4.30-mRNA-1 6 Reactome: R-HSA-174437;Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801 "Removal of the Flap Intermediate from the C-strand";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair" maker-scaffold49size896674-augustus-gene-1.0-mRNA-1 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" maker-scaffold264size273138-augustus-gene-1.8-mRNA-1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" maker-scaffold672size60097-augustus-gene-0.3-mRNA-1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex" maker-scaffold349size205196-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" augustus-scaffold627size70002-processed-gene-0.0-mRNA-1 14 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-5662702;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Viral mRNA Translation";"Peptide chain elongation";"Melanin biosynthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" maker-scaffold25size1130848-augustus-gene-7.7-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" maker-scaffold185size368400-augustus-gene-2.13-mRNA-1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475 "Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis" maker-scaffold1size2756217-augustus-gene-24.0-mRNA-1 40 MetaCyc: PWY-7654;MetaCyc: PWY-5109;MetaCyc: PWY-7606;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-5177;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00410+4.2.1.17;KEGG: 00627+4.2.1.17;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-6883;MetaCyc: PWY-5138;KEGG: 00640+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-6946;MetaCyc: PWY-7656;MetaCyc: PWY-6944;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-6945;MetaCyc: PWY-6583;MetaCyc: PWY-7401;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779 "(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fermentation to 2-methylbutanoate";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Valine, leucine and isoleucine degradation";"Limonene and pinene degradation";"2-methylpropene degradation";"beta-Alanine metabolism";"Aminobenzoate degradation";"alpha-Linolenic acid metabolism";"Fatty acid salvage";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"Phenylalanine metabolism";"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Propanoate metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Spodoptera littoralis pheromone biosynthesis";"Androstenedione degradation";"Tryptophan metabolism";"4-hydroxybenzoate biosynthesis III (plants)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Geraniol degradation";"Methyl tert-butyl ether degradation" maker-scaffold25size1130848-augustus-gene-6.14-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold10size1426409-augustus-gene-13.6-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold34size991984-augustus-gene-3.14-mRNA-1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" maker-scaffold157size419459-augustus-gene-3.23-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold2size2657229-augustus-gene-13.0-mRNA-1 6 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen degradation";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" maker-scaffold153size420471-augustus-gene-2.1-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold248size292329-augustus-gene-1.5-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold144size431038-augustus-gene-0.0-mRNA-1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" maker-scaffold19size1242042-augustus-gene-11.14-mRNA-1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" maker-scaffold1size2756217-augustus-gene-17.11-mRNA-1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-72163 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"mRNA Splicing - Major Pathway" maker-scaffold1size2756217-augustus-gene-26.0-mRNA-1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" maker-scaffold50size801739-augustus-gene-6.0-mRNA-1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" maker-scaffold281size259073-augustus-gene-0.1-mRNA-1 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" maker-scaffold96size574823-augustus-gene-3.12-mRNA-1 9 Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142 "Biotin transport and metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" maker-scaffold271size267669-augustus-gene-1.0-mRNA-1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" maker-scaffold1464size19164-augustus-gene-0.0-mRNA-1 3 KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" maker-scaffold248size292329-augustus-gene-1.9-mRNA-1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold169size953240-augustus-gene-8.20-mRNA-1 7 Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" maker-scaffold1size2756217-augustus-gene-17.5-mRNA-1 1 Reactome: R-HSA-400253 "Circadian Clock" maker-scaffold1200size24554-augustus-gene-0.0-mRNA-1 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" maker-scaffold99size561911-augustus-gene-2.4-mRNA-1 1 Reactome: R-HSA-8935690 "Digestion" maker-scaffold14size1670589-augustus-gene-6.5-mRNA-1 6 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" maker-scaffold34size991984-augustus-gene-9.9-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold4064size4083-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold3052size7221-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11 "Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold31size1053862-augustus-gene-2.9-mRNA-1 5 Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging" maker-scaffold187size362697-augustus-gene-2.10-mRNA-1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-350562 "Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)" maker-scaffold2size2657229-augustus-gene-10.0-mRNA-1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" maker-scaffold22size1201825-augustus-gene-0.2-mRNA-1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway" maker-scaffold14size1670589-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760 "snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation" maker-scaffold147size424191-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold2size2657229-augustus-gene-14.5-mRNA-1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" maker-scaffold272size266709-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" maker-scaffold2668size8606-augustus-gene-0.0-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" maker-scaffold270size268122-augustus-gene-1.8-mRNA-1 7 Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214 "Meiotic synapsis";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins" maker-scaffold34size991984-augustus-gene-4.4-mRNA-1 14 Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-7417;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-5981 "Synthesis of PA";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III" maker-scaffold17size1249603-augustus-gene-11.34-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold49size896674-augustus-gene-5.3-mRNA-1 33 Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-2467813 "SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Separation of Sister Chromatids" maker-scaffold19size1242042-augustus-gene-5.9-mRNA-1 9 Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616 "Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication" maker-scaffold2size2657229-augustus-gene-8.1-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold9size1444705-augustus-gene-4.11-mRNA-1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling" maker-scaffold350size203295-augustus-gene-1.8-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold701size56601-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold10size1426409-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" maker-scaffold24size1136029-augustus-gene-10.5-mRNA-1 10 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"HATs acetylate histones";"Human immunodeficiency virus 1 infection";"Ub-specific processing proteases";"Human cytomegalovirus infection" maker-scaffold10size1426409-augustus-gene-2.11-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold84size638750-augustus-gene-4.7-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" augustus-scaffold548size90716-processed-gene-0.7-mRNA-1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" maker-scaffold460size128090-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" maker-scaffold163size408523-augustus-gene-0.6-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold5967size13102-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" maker-scaffold13size1375079-augustus-gene-7.7-mRNA-1 13 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5537 "C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V" maker-scaffold100size555673-augustus-gene-3.3-mRNA-1 4 Reactome: R-HSA-72731;MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" maker-scaffold364size352455-augustus-gene-2.2-mRNA-1 19 KEGG: 00960+1.4.3.21;KEGG: 00950+1.4.3.21;Reactome: R-HSA-167243;Reactome: R-HSA-211945;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;KEGG: 00360+1.4.3.21;Reactome: R-HSA-167287;KEGG: 00350+1.4.3.21;Reactome: R-HSA-167246;Reactome: R-HSA-167200;KEGG: 00410+1.4.3.21;Reactome: R-HSA-167238;Reactome: R-HSA-674695;KEGG: 00260+1.4.3.21;Reactome: R-HSA-112382;MetaCyc: PWY-5751;Reactome: R-HSA-75955;Reactome: R-HSA-167152 "Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tat-mediated HIV elongation arrest and recovery";"Phase I - Functionalization of compounds";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Phenylalanine metabolism";"HIV elongation arrest and recovery";"Tyrosine metabolism";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"beta-Alanine metabolism";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Glycine, serine and threonine metabolism";"Formation of RNA Pol II elongation complex";"Phenylethanol biosynthesis";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat" maker-scaffold2381size15053-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" maker-scaffold1699size15843-augustus-gene-0.2-mRNA-1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" maker-scaffold34size991984-augustus-gene-8.0-mRNA-1 14 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6798163 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Choline catabolism" maker-scaffold18size2240851-augustus-gene-0.2-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold78size655360-augustus-gene-3.1-mRNA-1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" maker-scaffold96size574823-augustus-gene-3.3-mRNA-1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway" maker-scaffold36size1013817-augustus-gene-7.5-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold93size585897-augustus-gene-4.6-mRNA-1 19 Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6807505;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-749476;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-76071;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557 "Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"RNA polymerase II transcribes snRNA genes";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis" maker-scaffold85size629767-augustus-gene-2.0-mRNA-1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-913709;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798 "RAB GEFs exchange GTP for GDP on RABs";"O-linked glycosylation of mucins";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell" maker-scaffold3458size5565-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold87size608750-augustus-gene-5.7-mRNA-1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" augustus-scaffold846size43098-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-6782861 "Synthesis of wybutosine at G37 of tRNA(Phe)" maker-scaffold14size1670589-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" maker-scaffold6size1916839-augustus-gene-5.0-mRNA-1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" maker-scaffold5size1727520-augustus-gene-5.3-mRNA-1 4 KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247 "beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids" maker-scaffold13size1375079-augustus-gene-3.3-mRNA-1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-2173796;Reactome: R-HSA-167200 "Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat" maker-scaffold39size909063-augustus-gene-3.5-mRNA-1 1 Reactome: R-HSA-186797 "Signaling by PDGF" augustus-scaffold3259size6169-processed-gene-0.1-mRNA-1 6 Reactome: R-HSA-8862803;Reactome: R-HSA-8950505;MetaCyc: PWY-6854;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" maker-scaffold19size1242042-augustus-gene-11.6-mRNA-1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" maker-scaffold278size260935-augustus-gene-1.3-mRNA-1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" maker-scaffold89size602897-augustus-gene-0.5-mRNA-1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold88size603654-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold10size1426409-augustus-gene-5.7-mRNA-1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" maker-scaffold805size46428-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold122size477764-augustus-gene-3.2-mRNA-1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" maker-scaffold158size418592-augustus-gene-1.1-mRNA-1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" maker-scaffold544size92723-augustus-gene-0.5-mRNA-1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" maker-scaffold154size420078-augustus-gene-0.0-mRNA-1 18 MetaCyc: PWY-8051;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00565+3.1.1.4 "Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Synthesis of PA";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Ether lipid metabolism" maker-scaffold367size190875-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold344size208274-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold154size420078-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" maker-scaffold681size58992-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" maker-scaffold7size1668642-augustus-gene-4.2-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold2size2657229-augustus-gene-13.5-mRNA-1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3000497 "VLDL assembly";"Post-translational protein phosphorylation";"Chylomicron assembly";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Chylomicron clearance";"LDL remodeling";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron remodeling";"VLDL clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Scavenging by Class H Receptors" maker-scaffold144size431038-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold23size1161859-augustus-gene-9.0-mRNA-1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" maker-scaffold386size172899-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" maker-scaffold73size681921-augustus-gene-4.4-mRNA-1 5 Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32;MetaCyc: PWY-7383 "Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" maker-scaffold499size127699-augustus-gene-0.2-mRNA-1 10 KEGG: 00710+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1 "Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Inositol phosphate metabolism";"Gluconeogenesis";"Glycolysis";"Glycolysis / Gluconeogenesis" maker-scaffold574size83631-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" maker-scaffold4995size3151-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" maker-scaffold1023size31993-augustus-gene-0.1-mRNA-1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" maker-scaffold493size110888-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" maker-scaffold1169size25791-augustus-gene-0.1-mRNA-1 17 Reactome: R-HSA-5362768;MetaCyc: PWY-6855;Reactome: R-HSA-532668;MetaCyc: PWY-7822;Reactome: R-HSA-5689877;Reactome: R-HSA-3371511;KEGG: 00520+3.2.1.14;Reactome: R-HSA-5678895;Reactome: R-HSA-8866654;Reactome: R-HSA-8876725;Reactome: R-HSA-110320;Reactome: R-HSA-5358346;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5689896;MetaCyc: PWY-6902;Reactome: R-HSA-9646399 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Chitin degradation I (archaea)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Chitin degradation III (Serratia)";"Josephin domain DUBs";"HSF1 activation";"Amino sugar and nucleotide sugar metabolism";"Defective CFTR causes cystic fibrosis";"E3 ubiquitin ligases ubiquitinate target proteins";"Protein methylation";"Translesion Synthesis by POLH";"Hedgehog ligand biogenesis";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Ovarian tumor domain proteases";"Chitin degradation II (Vibrio)";"Aggrephagy" maker-scaffold71size686415-augustus-gene-2.4-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold6613size2644-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold4size1754260-augustus-gene-13.3-mRNA-1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" maker-scaffold318size381727-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold14size1670589-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" maker-scaffold39size909063-augustus-gene-4.3-mRNA-1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825 "Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis" maker-scaffold572size84276-augustus-gene-0.7-mRNA-1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" maker-scaffold82size640827-augustus-gene-1.0-mRNA-1 10 KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7511;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Protein ubiquitination";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" maker-scaffold4size1754260-augustus-gene-16.2-mRNA-1 1 Reactome: R-HSA-71064 "Lysine catabolism" maker-scaffold9size1444705-augustus-gene-12.4-mRNA-1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" maker-scaffold10size1426409-augustus-gene-11.4-mRNA-1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" maker-scaffold2472size15045-augustus-gene-0.1-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold10size1426409-augustus-gene-11.6-mRNA-1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" augustus-scaffold727size53659-processed-gene-0.0-mRNA-1 11 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 00970+6.3.5.7;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Aminoacyl-tRNA biosynthesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK" maker-scaffold26size1667613-augustus-gene-10.1-mRNA-1 14 MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-7279;MetaCyc: PWY-6969 "Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" maker-scaffold35size976498-augustus-gene-1.0-mRNA-1 6 Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold3030size10792-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5679001;MetaCyc: PWY-6972;Reactome: R-HSA-189483 "ABC-family proteins mediated transport";"Defective ABCC2 causes Dubin-Johnson syndrome";"Oleandomycin activation/inactivation";"Heme degradation" maker-scaffold43size857109-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" maker-scaffold5size1727520-augustus-gene-9.2-mRNA-1 16 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression" maker-scaffold110size515606-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" maker-scaffold70size694644-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold2117size11813-augustus-gene-0.0-mRNA-1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" maker-scaffold530size96307-augustus-gene-0.1-mRNA-1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" maker-scaffold19size1242042-augustus-gene-10.0-mRNA-1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159236 "Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold397size365563-augustus-gene-2.12-mRNA-1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" maker-scaffold9size1444705-augustus-gene-12.2-mRNA-1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" maker-scaffold280size266829-augustus-gene-1.2-mRNA-1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold85size629767-augustus-gene-2.3-mRNA-1 4 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis" maker-scaffold1size2756217-augustus-gene-8.9-mRNA-1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" maker-scaffold397size365563-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold42size1661181-augustus-gene-8.2-mRNA-1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" maker-scaffold47size1319914-augustus-gene-12.0-mRNA-1 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" maker-scaffold48size811354-augustus-gene-1.3-mRNA-1 4 MetaCyc: PWY-6829;Reactome: R-HSA-1369062;Reactome: R-HSA-1268020;Reactome: R-HSA-9603798 "Trna methylation (yeast)";"ABC transporters in lipid homeostasis";"Mitochondrial protein import";"Class I peroxisomal membrane protein import" maker-scaffold1638size16583-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" maker-scaffold238size302402-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold72size687670-augustus-gene-4.2-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold8size1945031-augustus-gene-8.0-mRNA-1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" maker-scaffold676size59440-augustus-gene-0.1-mRNA-1 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" maker-scaffold14size1670589-augustus-gene-6.3-mRNA-1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway" maker-scaffold855size42418-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" maker-scaffold122size477764-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" maker-scaffold9size1444705-augustus-gene-4.23-mRNA-1 7 Reactome: R-HSA-201681;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-201688;Reactome: R-HSA-4086400 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"WNT mediated activation of DVL";"PCP/CE pathway" maker-scaffold34069size7329-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" maker-scaffold59size767954-augustus-gene-4.8-mRNA-1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" augustus-scaffold1915size13442-processed-gene-0.0-mRNA-1 181 Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-2173788;Reactome: R-HSA-110320;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-110314;Reactome: R-HSA-174178;Reactome: R-HSA-9636383;Reactome: R-HSA-9633012;Reactome: R-HSA-4641258;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-168927;Reactome: R-HSA-156827;Reactome: R-HSA-9645460;Reactome: R-HSA-69481;Reactome: R-HSA-209543;Reactome: R-HSA-6782210;Reactome: R-HSA-5689901;Reactome: R-HSA-2173795;Reactome: R-HSA-5362768;Reactome: R-HSA-1358803;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-110312;Reactome: R-HSA-1234176;Reactome: R-HSA-5696395;Reactome: R-HSA-983168;Reactome: R-HSA-5678895;Reactome: R-HSA-205043;Reactome: R-HSA-1236382;Reactome: R-HSA-2122947;Reactome: R-HSA-2408557;Reactome: R-HSA-2565942;Reactome: R-HSA-174084;Reactome: R-HSA-9646399;Reactome: R-HSA-192823;Reactome: R-HSA-9013507;Reactome: R-HSA-2559582;Reactome: R-HSA-901032;Reactome: R-HSA-3769402;Reactome: R-HSA-445989;Reactome: R-HSA-937039;Reactome: R-HSA-2871837;Reactome: R-HSA-187577;Reactome: R-HSA-2173791;Reactome: R-HSA-6804756;Reactome: R-HSA-8866654;Reactome: R-HSA-975110;Reactome: R-HSA-937042;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-912631;Reactome: R-HSA-69541;Reactome: R-HSA-8939236;Reactome: R-HSA-975144;Reactome: R-HSA-8856828;Reactome: R-HSA-5654732;Reactome: R-HSA-69231;Reactome: R-HSA-1268020;Reactome: R-HSA-5358346;Reactome: R-HSA-2173796;Reactome: R-HSA-5693565;Reactome: R-HSA-72706;Reactome: R-HSA-201681;Reactome: R-HSA-8939902;Reactome: R-HSA-936964;Reactome: R-HSA-8876493;Reactome: R-HSA-450321;Reactome: R-HSA-195253;Reactome: R-HSA-156902;Reactome: R-HSA-5610783;Reactome: R-HSA-3785653;Reactome: R-HSA-5205685;Reactome: R-HSA-6782135;Reactome: R-HSA-8948751;Reactome: R-HSA-975956;Reactome: R-HSA-168638;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-937041;Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-1169091;Reactome: R-HSA-6791226;Reactome: R-HSA-211733;Reactome: R-HSA-174490;Reactome: R-HSA-5696397;Reactome: R-HSA-5675482;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-72764;Reactome: R-HSA-8875360;Reactome: R-HSA-174154;Reactome: R-HSA-4641263;Reactome: R-HSA-8849469;Reactome: R-HSA-8863795;Reactome: R-HSA-6804760;Reactome: R-HSA-168928;Reactome: R-HSA-6781827;Reactome: R-HSA-5687128;Reactome: R-HSA-936440;Reactome: R-HSA-5357956;Reactome: R-HSA-2894862;Reactome: R-HSA-917937;Reactome: R-HSA-937072;Reactome: R-HSA-2467813;Reactome: R-HSA-2672351;Reactome: R-HSA-5685942;Reactome: R-HSA-2559580;Reactome: R-HSA-2691232;Reactome: R-HSA-450302;Reactome: R-HSA-5689877;Reactome: R-HSA-68827;Reactome: R-HSA-9013973;Reactome: R-HSA-9637628;Reactome: R-HSA-2559585;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-2644606;Reactome: R-HSA-5655862;Reactome: R-HSA-6807004;Reactome: R-HSA-5357905;Reactome: R-HSA-4608870;Reactome: R-HSA-6804757;Reactome: R-HSA-9604323;Reactome: R-HSA-3322077;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-5675221;Reactome: R-HSA-9615710;Reactome: R-HSA-9033241;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-6781823;Reactome: R-HSA-977225;Reactome: R-HSA-917729;Reactome: R-HSA-209560;Reactome: R-HSA-202424;Reactome: R-HSA-5696400;Reactome: R-HSA-349425;Reactome: R-HSA-5654726;Reactome: R-HSA-75815;Reactome: R-HSA-174048;Reactome: R-HSA-182971;Reactome: R-HSA-1253288;Reactome: R-HSA-2122948;Reactome: R-HSA-1236974;Reactome: R-HSA-5656169;Reactome: R-HSA-8856825;Reactome: R-HSA-6783310;Reactome: R-HSA-5668541;Reactome: R-HSA-2979096;Reactome: R-HSA-8852276;Reactome: R-HSA-71403;Reactome: R-HSA-72689;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-175474;Reactome: R-HSA-1295596;Reactome: R-HSA-8854050;Reactome: R-HSA-5693607;Reactome: R-HSA-9613829;Reactome: R-HSA-5656121;Reactome: R-HSA-162588;Reactome: R-HSA-5689896;Reactome: R-HSA-180534;Reactome: R-HSA-1169408;Reactome: R-HSA-400253;Reactome: R-HSA-179409;Reactome: R-HSA-4641257;Reactome: R-HSA-3134975;Reactome: R-HSA-9014325;Reactome: R-HSA-5654727;Reactome: R-HSA-5658442;Reactome: R-HSA-5689603;Reactome: R-HSA-5654733 "Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Downregulation of TGF-beta receptor signaling";"Translesion Synthesis by POLH";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Recognition of DNA damage by PCNA-containing replication complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Prevention of phagosomal-lysosomal fusion";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Degradation of DVL";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"TICAM1, RIP1-mediated IKK complex recruitment";"L13a-mediated translational silencing of Ceruloplasmin expression";"Alpha-protein kinase 1 signaling pathway";"G2/M Checkpoints";"p75NTR recruits signalling complexes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Metalloprotease DUBs";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2:ERBB3 signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Translesion synthesis by REV1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of Incision Complex in GG-NER";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective CFTR causes cystic fibrosis";"NRIF signals cell death from the nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NOTCH1 Intracellular Domain Regulates Transcription";"Selenocysteine synthesis";"Regulation of PLK1 Activity at G2/M Transition";"Autodegradation of Cdh1 by Cdh1:APC/C";"Aggrephagy";"Viral mRNA Translation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Senescence-Associated Secretory Phenotype (SASP)";"ER Quality Control Compartment (ERQC)";"Deactivation of the beta-catenin transactivating complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK1 recruits IKK complex";"FCERI mediated NF-kB activation";"SCF(Skp2)-mediated degradation of p27/p21";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of TP53 Activity through Phosphorylation";"E3 ubiquitin ligases ubiquitinate target proteins";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"IRAK2 mediated activation of TAK1 complex";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of signaling by CBL";"Stabilization of p53";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Cyclin D associated events in G1";"Mitochondrial protein import";"Hedgehog ligand biogenesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TCF dependent signaling in response to WNT";"Regulation of RUNX2 expression and activity";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"InlA-mediated entry of Listeria monocytogenes into host cells";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Degradation of beta-catenin by the destruction complex";"Peptide chain elongation";"Degradation of GLI2 by the proteasome";"Myoclonic epilepsy of Lafora";"Pink/Parkin Mediated Mitophagy";"Dual incision in TC-NER";"Regulation of PTEN stability and activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"NOD1/2 Signaling Pathway";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"IKK complex recruitment mediated by RIP1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"Activation of NF-kappaB in B cells";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Membrane binding and targetting of GAG proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of necroptotic cell death";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Eukaryotic Translation Termination";"InlB-mediated entry of Listeria monocytogenes into host cell";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of FZD by ubiquitination";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downregulation of ERBB2 signaling";"Regulation of TP53 Activity through Methylation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"MAPK6/MAPK4 signaling";"Negative regulators of DDX58/IFIH1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Iron uptake and transport";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Separation of Sister Chromatids";"Stimuli-sensing channels";"HDR through Homologous Recombination (HRR)";"Oxidative Stress Induced Senescence";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"activated TAK1 mediates p38 MAPK activation";"Josephin domain DUBs";"CDT1 association with the CDC6:ORC:origin complex";"TICAM1-dependent activation of IRF3/IRF7";"Modulation by Mtb of host immune system";"Oncogene Induced Senescence";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Translesion synthesis by POLK";"Negative regulation of MET activity";"Regulation of TNFR1 signaling";"Asymmetric localization of PCP proteins";"Regulation of TP53 Degradation";"Negative regulation of NOTCH4 signaling";"Glycogen synthesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of MAPK pathway";"Late endosomal microautophagy";"Peroxisomal protein import";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Formation of TC-NER Pre-Incision Complex";"Amyloid fiber formation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"NF-kB is activated and signals survival";"Downstream TCR signaling";"Dual Incision in GG-NER";"Autodegradation of the E3 ubiquitin ligase COP1";"Negative regulation of FGFR1 signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Cyclin B";"EGFR downregulation";"Downregulation of ERBB4 signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"ER-Phagosome pathway";"Termination of translesion DNA synthesis";"Cargo recognition for clathrin-mediated endocytosis";"Fanconi Anemia Pathway";"TNFR2 non-canonical NF-kB pathway";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Citric acid cycle (TCA cycle)";"Formation of a pool of free 40S subunits";"Neddylation";"Degradation of GLI1 by the proteasome";"Assembly Of The HIV Virion";"Spry regulation of FGF signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Processing of DNA double-strand break ends";"Chaperone Mediated Autophagy";"Translesion synthesis by POLI";"Budding and maturation of HIV virion";"Ovarian tumor domain proteases";"Vpu mediated degradation of CD4";"ISG15 antiviral mechanism";"Circadian Clock";"APC-Cdc20 mediated degradation of Nek2A";"Degradation of AXIN";"Regulation of innate immune responses to cytosolic DNA";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Negative regulation of FGFR2 signaling";"Regulation of RAS by GAPs";"UCH proteinases";"Negative regulation of FGFR4 signaling" maker-scaffold145size712617-augustus-gene-6.15-mRNA-1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" augustus-scaffold1323size21562-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold11size1424826-augustus-gene-8.7-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold29size1057726-augustus-gene-9.5-mRNA-1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" maker-scaffold484size118506-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" augustus-scaffold3512size5461-processed-gene-0.0-mRNA-1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747 "Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RAF activation";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated" maker-scaffold37size976698-augustus-gene-7.4-mRNA-1 19 Reactome: R-HSA-156902;Reactome: R-HSA-3214858;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-8876725 "Peptide chain elongation";"RMTs methylate histone arginines";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Protein methylation" augustus-scaffold738size52489-processed-gene-0.1-mRNA-1 88 Reactome: R-HSA-68867;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;MetaCyc: PWY-2941;MetaCyc: PWY-6728;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-68962;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;KEGG: 00660+6.2.1.5;KEGG: 00260+2.7.2.4;MetaCyc: PWY-2942;Reactome: R-HSA-4608870;MetaCyc: PWY-7977;Reactome: R-HSA-350562;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-8964539;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;KEGG: 00270+2.7.2.4;Reactome: R-HSA-68827;MetaCyc: PWY-6562;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;MetaCyc: PWY-8088;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;MetaCyc: PWY-5538;MetaCyc: PWY-5392;Reactome: R-HSA-174154;MetaCyc: PWY-5097;MetaCyc: PWY-6559;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;MetaCyc: PWY-5690;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;KEGG: 00640+6.2.1.5;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;MetaCyc: PWY-5913;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;MetaCyc: PWY-5537;KEGG: 00261+2.7.2.4;Reactome: R-HSA-8948751;KEGG: 00720+6.2.1.5;Reactome: R-HSA-176974;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;MetaCyc: PWY-7153;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-8852276;KEGG: 00300+2.7.2.4;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-176187;MetaCyc: PWY-6969;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-69052;MetaCyc: PWY-6160;Reactome: R-HSA-174113;MetaCyc: PWY-7511;Reactome: R-HSA-5676590 "Assembly of the pre-replicative complex";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"L-lysine biosynthesis II";"Methylaspartate cycle";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of the pre-replicative complex";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"C5-Branched dibasic acid metabolism";"Glycine, serine and threonine metabolism";"L-lysine biosynthesis III";"Asymmetric localization of PCP proteins";"L-methionine biosynthesis IV (archaea)";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Glutamate and glutamine metabolism";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cysteine and methionine metabolism";"CDT1 association with the CDC6:ORC:origin complex";"Norspermidine biosynthesis";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dipicolinate biosynthesis";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"APC/C:Cdc20 mediated degradation of Securin";"L-lysine biosynthesis VI";"Spermidine biosynthesis II";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Regulation of RUNX3 expression and activity";"TCA cycle II (plants and fungi)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Propanoate metabolism";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Partial TCA cycle (obligate autotrophs)";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Pyruvate fermentation to acetate V";"Monobactam biosynthesis";"Regulation of PTEN stability and activity";"Carbon fixation pathways in prokaryotes";"Unwinding of DNA";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Grixazone biosynthesis";"Degradation of GLI1 by the proteasome";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Lysine biosynthesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Activation of ATR in response to replication stress";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Ub-specific processing proteases";"Switching of origins to a post-replicative state";"3-dehydroquinate biosynthesis II (archaea)";"SCF-beta-TrCP mediated degradation of Emi1";"Protein ubiquitination";"NIK-->noncanonical NF-kB signaling" maker-scaffold6size1916839-augustus-gene-15.1-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold324size218590-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" maker-scaffold30size1054049-augustus-gene-9.1-mRNA-1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" maker-scaffold18648size7229-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold70size694644-augustus-gene-2.2-mRNA-1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" maker-scaffold602size77912-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" augustus-scaffold900size38948-processed-gene-0.0-mRNA-1 8 MetaCyc: PWY-6664;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-2301;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4 "Di-myo-inositol phosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis" maker-scaffold5size1727520-augustus-gene-8.12-mRNA-1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" maker-scaffold162size411881-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold2size2657229-augustus-gene-1.7-mRNA-1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-5619107 "ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" maker-scaffold6size1916839-augustus-gene-3.2-mRNA-1 6 KEGG: 00030+1.1.1.49;Reactome: R-HSA-381340;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;Reactome: R-HSA-1989781 "Pentose phosphate pathway";"Transcriptional regulation of white adipocyte differentiation";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"PPARA activates gene expression" maker-scaffold316size224156-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold266size269306-augustus-gene-1.19-mRNA-1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" maker-scaffold147size424191-augustus-gene-2.10-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold2size2657229-augustus-gene-21.1-mRNA-1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" maker-scaffold603size77277-augustus-gene-0.2-mRNA-1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" maker-scaffold25size1130848-augustus-gene-6.10-mRNA-1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" maker-scaffold54size1273868-augustus-gene-10.4-mRNA-1 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" maker-scaffold11size1424826-augustus-gene-7.4-mRNA-1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" maker-scaffold75size670735-augustus-gene-5.11-mRNA-1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" maker-scaffold15236size7245-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" maker-scaffold5936size9736-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" maker-scaffold1380size20557-augustus-gene-0.2-mRNA-1 4 Reactome: R-HSA-6782315;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "tRNA modification in the nucleus and cytosol";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" maker-scaffold134size449309-augustus-gene-3.2-mRNA-1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" maker-scaffold161size412613-augustus-gene-3.8-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold47size1319914-augustus-gene-6.3-mRNA-1 3 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924;Reactome: R-HSA-1483148 "Hedgehog 'off' state";"Intraflagellar transport";"Synthesis of PG" maker-scaffold1size2756217-augustus-gene-17.0-mRNA-1 8 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold21size1197050-augustus-gene-1.2-mRNA-1 6 KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" maker-scaffold45size832949-augustus-gene-7.0-mRNA-1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" maker-scaffold28size1079920-augustus-gene-6.3-mRNA-1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" maker-scaffold33size1007119-augustus-gene-9.4-mRNA-1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" maker-scaffold73size681921-augustus-gene-2.6-mRNA-1 14 Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-167243 "TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery" maker-scaffold1492size18671-augustus-gene-0.1-mRNA-1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis" maker-scaffold2size2657229-augustus-gene-25.9-mRNA-1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" maker-scaffold256size285501-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-425986 "Stimuli-sensing channels";"Sodium/Proton exchangers" maker-scaffold404size154060-augustus-gene-0.4-mRNA-1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions" maker-scaffold100size555673-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold26size1667613-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" maker-scaffold101size554424-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" maker-scaffold2409size9749-augustus-gene-0.1-mRNA-1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold22size1201825-augustus-gene-4.2-mRNA-1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" maker-scaffold3757size5006-augustus-gene-0.0-mRNA-1 13 MetaCyc: PWY-6370;Reactome: R-HSA-196836;MetaCyc: PWY-6842;KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-7533;MetaCyc: PWY-7112;KEGG: 00053+1.8.5.1 "Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification II";"Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - other enzymes";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Ascorbate and aldarate metabolism" maker-scaffold4535size3432-augustus-gene-0.1-mRNA-1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold48size811354-augustus-gene-7.14-mRNA-1 12 MetaCyc: PWY-7857;MetaCyc: PWY-5132;KEGG: 00640+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00720+6.2.1.1 "Adlupulone and adhumulone biosynthesis";"Lupulone and humulone biosynthesis";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Chitin degradation to ethanol";"Methane metabolism";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Carbon fixation pathways in prokaryotes" maker-scaffold43size857109-augustus-gene-4.15-mRNA-1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" maker-scaffold12size1412574-augustus-gene-11.1-mRNA-1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" maker-scaffold105size529344-augustus-gene-3.0-mRNA-1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" maker-scaffold16517size7317-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" maker-scaffold4678size3323-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-418346;Reactome: R-HSA-139853 "Platelet homeostasis";"Elevation of cytosolic Ca2+ levels" maker-scaffold9size1444705-augustus-gene-13.2-mRNA-1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" maker-scaffold45size832949-augustus-gene-4.4-mRNA-1 5 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Trafficking and processing of endosomal TLR";"MHC class II antigen presentation";"Neutrophil degranulation" maker-scaffold1006size32773-augustus-gene-0.1-mRNA-1 7 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" maker-scaffold260size277064-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" maker-scaffold14size1670589-augustus-gene-11.1-mRNA-1 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" maker-scaffold1003size33056-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold21size1197050-augustus-gene-1.0-mRNA-1 14 MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5392;Reactome: R-HSA-1296072 "Methylaspartate cycle";"Propanoate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Reductive TCA cycle II";"Voltage gated Potassium channels" maker-scaffold28size1079920-augustus-gene-6.7-mRNA-1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold22size1201825-augustus-gene-4.4-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold720size85827-augustus-gene-0.2-mRNA-1 10 MetaCyc: PWY-7344;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328 "UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" maker-scaffold5size1727520-augustus-gene-8.13-mRNA-1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" maker-scaffold96size574823-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" augustus-scaffold5406size9730-processed-gene-0.0-mRNA-1 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" maker-scaffold37size976698-augustus-gene-8.2-mRNA-1 3 KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism" maker-scaffold8size1945031-augustus-gene-6.1-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold254size288410-augustus-gene-1.7-mRNA-1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" maker-scaffold321size220589-augustus-gene-0.1-mRNA-1 24 Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-983189 "MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Kinesins" maker-scaffold19size1242042-augustus-gene-11.5-mRNA-1 11 MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5381;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-7821;MetaCyc: PWY-6608 "Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Purine metabolism";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation III" maker-scaffold5488size2974-augustus-gene-0.1-mRNA-1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" maker-scaffold180size376838-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold315size226392-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" maker-scaffold9size1444705-augustus-gene-1.0-mRNA-1 4 MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism" maker-scaffold12171size8048-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" maker-scaffold8size1945031-augustus-gene-11.3-mRNA-1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" maker-scaffold76size663279-augustus-gene-5.8-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" augustus-scaffold2208size10866-processed-gene-0.1-mRNA-1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" augustus-scaffold3510size5461-processed-gene-0.1-mRNA-1 22 Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"RAF activation";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" maker-scaffold493size110888-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" maker-scaffold33size1007119-augustus-gene-9.3-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold37size976698-augustus-gene-7.6-mRNA-1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" maker-scaffold5size1727520-augustus-gene-9.5-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold216size329809-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold89size602897-augustus-gene-5.25-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold238size302402-augustus-gene-1.0-mRNA-1 16 Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226 "Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold3size2782310-augustus-gene-20.1-mRNA-1 3 KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" maker-scaffold1578size17243-augustus-gene-0.1-mRNA-1 14 Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8943723 "Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation" maker-scaffold3size2782310-augustus-gene-6.0-mRNA-1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-180534 "Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4" maker-scaffold89size602897-augustus-gene-5.22-mRNA-1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237 "HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2" maker-scaffold72size687670-augustus-gene-1.4-mRNA-1 6 MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate" maker-scaffold136size447168-augustus-gene-3.1-mRNA-1 21 Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00660+6.2.1.5;KEGG: 00720+2.3.3.8;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;MetaCyc: PWY-5537;Reactome: R-HSA-1268020;MetaCyc: PWY-6969;Reactome: R-HSA-75105;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;Reactome: R-HSA-216083 "ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate V";"Mitochondrial protein import";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Integrin cell surface interactions" maker-scaffold19size1242042-augustus-gene-5.2-mRNA-1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" maker-scaffold14size1670589-augustus-gene-12.2-mRNA-1 10 Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-5607761;Reactome: R-HSA-2565942;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of PLK1 Activity at G2/M Transition";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" maker-scaffold238size302402-augustus-gene-2.17-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold70size694644-augustus-gene-4.4-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold1711size15735-augustus-gene-0.1-mRNA-1 18 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-611105;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6799198;Reactome: R-HSA-72702 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Respiratory electron transport";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Complex I biogenesis";"Ribosomal scanning and start codon recognition" maker-scaffold281size259073-augustus-gene-1.4-mRNA-1 7 MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204 "2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol" maker-scaffold33size1007119-augustus-gene-2.0-mRNA-1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation" maker-scaffold22size1201825-augustus-gene-5.7-mRNA-1 8 KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-71336;MetaCyc: PWY-1861;Reactome: R-HSA-163754;Reactome: R-HSA-6791055 "Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P" maker-scaffold28size1079920-augustus-gene-2.3-mRNA-1 5 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" maker-scaffold575size82809-augustus-gene-0.2-mRNA-1 56 Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9604323 "Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling" maker-scaffold1size2756217-augustus-gene-26.15-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold1size2756217-augustus-gene-26.19-mRNA-1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" maker-scaffold1size2756217-augustus-gene-20.7-mRNA-1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" maker-scaffold638size73239-augustus-gene-0.5-mRNA-1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870 "Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Orc1 removal from chromatin";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins" maker-scaffold12885size7464-augustus-gene-0.1-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold231size308180-augustus-gene-2.6-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold53size789746-augustus-gene-7.3-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold5size1727520-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold67size700687-augustus-gene-0.2-mRNA-1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" maker-scaffold22size1201825-augustus-gene-9.2-mRNA-1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" maker-scaffold78size655360-augustus-gene-5.16-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold2size2657229-augustus-gene-24.2-mRNA-1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" augustus-scaffold1079size29548-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00480+3.4.11.1;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Glutathione metabolism";"Purine metabolism" augustus-scaffold1192size24751-processed-gene-0.0-mRNA-1 57 Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-426048;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949 "Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Arachidonate production from DAG";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin" maker-scaffold80size1421260-augustus-gene-3.0-mRNA-1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation" augustus-scaffold2925size7701-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" maker-scaffold85size629767-augustus-gene-1.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold337size211899-augustus-gene-1.2-mRNA-1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756 "Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation" maker-scaffold50size801739-augustus-gene-7.14-mRNA-1 12 MetaCyc: PWY-7238;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00040+2.7.7.9;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9 "Sucrose biosynthesis II";"Glycogen synthesis";"Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Pentose and glucuronate interconversions";"Stachyose degradation";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" maker-scaffold349size205196-augustus-gene-1.5-mRNA-1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" maker-scaffold513size110971-augustus-gene-0.3-mRNA-1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" maker-scaffold10size1426409-augustus-gene-9.10-mRNA-1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" maker-scaffold76size663279-augustus-gene-4.8-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold618size72265-augustus-gene-0.2-mRNA-1 7 Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25 "Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Starch degradation II";"Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch and sucrose metabolism" maker-scaffold100size555673-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" augustus-scaffold1531size18066-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" maker-scaffold105size529344-augustus-gene-4.9-mRNA-1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885 "SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA replication proteins" maker-scaffold37size976698-augustus-gene-6.9-mRNA-1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" maker-scaffold29size1057726-augustus-gene-9.0-mRNA-1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" maker-scaffold11size1424826-augustus-gene-9.2-mRNA-1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" maker-scaffold96size574823-augustus-gene-2.4-mRNA-1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" maker-scaffold2958size7621-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-71403;Reactome: R-HSA-426048 "Citric acid cycle (TCA cycle)";"Arachidonate production from DAG" maker-scaffold52size909272-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-376172 "DSCAM interactions" maker-scaffold13size1375079-augustus-gene-7.3-mRNA-1 6 KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-5484;MetaCyc: PWY-1622;KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004 "Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Entner-Doudoroff pathway I" maker-scaffold72size687670-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" augustus-scaffold1425size19780-processed-gene-0.1-mRNA-1 5 Reactome: R-HSA-5693579;KEGG: 00970+6.1.1.2;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Aminoacyl-tRNA biosynthesis";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" maker-scaffold16size1255579-augustus-gene-11.4-mRNA-1 4 Reactome: R-HSA-72086;MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "mRNA Capping";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" maker-scaffold12size1412574-augustus-gene-6.0-mRNA-1 5 Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" augustus-scaffold1761size15118-processed-gene-0.1-mRNA-1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" maker-scaffold5575size2945-augustus-gene-0.0-mRNA-1 9 MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-7852 "Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)" maker-scaffold2size2657229-augustus-gene-10.6-mRNA-1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" maker-scaffold82size640827-augustus-gene-4.0-mRNA-1 56 Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751 "Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity" maker-scaffold101size554424-augustus-gene-4.2-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold22size1201825-augustus-gene-11.3-mRNA-1 9 Reactome: R-HSA-917729;Reactome: R-HSA-189451;Reactome: R-HSA-9615710;KEGG: 00860+4.2.1.75;Reactome: R-HSA-162588;Reactome: R-HSA-174490;MetaCyc: PWY-5188;Reactome: R-HSA-9610379;MetaCyc: PWY-5189 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Heme biosynthesis";"Late endosomal microautophagy";"Porphyrin and chlorophyll metabolism";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Tetrapyrrole biosynthesis I (from glutamate)";"HCMV Late Events";"Tetrapyrrole biosynthesis II (from glycine)" maker-scaffold80size1421260-augustus-gene-7.3-mRNA-1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" maker-scaffold10size1426409-augustus-gene-6.1-mRNA-1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-6804760;Reactome: R-HSA-2299718 "PKMTs methylate histone lysines";"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes" maker-scaffold2286size15097-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" maker-scaffold8size1945031-augustus-gene-13.3-mRNA-1 4 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" maker-scaffold105size529344-augustus-gene-4.6-mRNA-1 6 MetaCyc: PWY-6627;MetaCyc: PWY-7626;MetaCyc: PWY-3461;MetaCyc: PWY-3462;KEGG: 00400+5.4.99.5;MetaCyc: PWY-6120 "Salinosporamide A biosynthesis";"Bacilysin biosynthesis";"L-tyrosine biosynthesis II";"L-phenylalanine biosynthesis II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis III" maker-scaffold990size33689-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold26size1667613-augustus-gene-10.7-mRNA-1 5 KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185 "Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I" maker-scaffold70476size7165-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold34size991984-augustus-gene-2.1-mRNA-1 59 Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5689901;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;KEGG: 00970+6.3.5.7;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-983168 "Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Hedgehog 'on' state";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"ER-Phagosome pathway";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Metalloprotease DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Aminoacyl-tRNA biosynthesis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold72size687670-augustus-gene-5.8-mRNA-1 12 Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167243 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery" maker-scaffold24size1136029-augustus-gene-10.3-mRNA-1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" maker-scaffold551size89207-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold76size663279-augustus-gene-4.19-mRNA-1 5 KEGG: 00510+3.2.1.106;Reactome: R-HSA-4793954;MetaCyc: PWY-7918;Reactome: R-HSA-532668;MetaCyc: PWY-7919 "N-Glycan biosynthesis";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (plants and animals)" maker-scaffold342size295439-augustus-gene-1.2-mRNA-1 5 Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225 "Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" maker-scaffold16size1255579-augustus-gene-6.5-mRNA-1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" maker-scaffold819size45309-augustus-gene-0.0-mRNA-1 8 KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288 "Photosynthesis";"Oxidative phosphorylation";"Insulin receptor recycling";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1" maker-scaffold43size857109-augustus-gene-4.11-mRNA-1 1 Reactome: R-HSA-1483101 "Synthesis of PS" maker-scaffold234size306624-augustus-gene-2.4-mRNA-1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold105size529344-augustus-gene-4.7-mRNA-1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" maker-scaffold84size638750-augustus-gene-5.6-mRNA-1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" augustus-scaffold406size153845-processed-gene-0.2-mRNA-1 5 Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912420 "Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi" maker-scaffold3size2782310-augustus-gene-6.1-mRNA-1 17 Reactome: R-HSA-2426168;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-163765;MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-5789 "Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate cycle";"Propanoate metabolism";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Pyruvate metabolism";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" maker-scaffold3331size12381-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-8876725 "Stimuli-sensing channels";"Protein methylation" maker-scaffold568size85143-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" maker-scaffold145size712617-augustus-gene-3.4-mRNA-1 9 Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-1362277 "Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex" maker-scaffold190size360960-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" maker-scaffold1size2756217-augustus-gene-8.6-mRNA-1 2 Reactome: R-HSA-5676934;Reactome: R-HSA-429947 "Protein repair";"Deadenylation of mRNA" maker-scaffold38size924328-augustus-gene-0.6-mRNA-1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" maker-scaffold524size99361-augustus-gene-0.2-mRNA-1 4 Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" maker-scaffold714size54663-augustus-gene-0.2-mRNA-1 7 MetaCyc: PWY-8043;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;Reactome: R-HSA-174403;MetaCyc: PWY-7255 "Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)" maker-scaffold2size2657229-augustus-gene-25.13-mRNA-1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" maker-scaffold5712size2901-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1300642 "Sperm Motility And Taxes" maker-scaffold47size1319914-augustus-gene-6.4-mRNA-1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" maker-scaffold4size1754260-augustus-gene-16.4-mRNA-1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" augustus-scaffold984size34049-processed-gene-0.1-mRNA-1 6 MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;MetaCyc: PWY-5514;MetaCyc: PWY-8004 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I" maker-scaffold42size1661181-augustus-gene-15.3-mRNA-1 7 MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;Reactome: R-HSA-4549356;MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" augustus-scaffold967size35158-processed-gene-0.0-mRNA-1 4 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis" maker-scaffold22size1201825-augustus-gene-4.5-mRNA-1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis" maker-scaffold105size529344-augustus-gene-4.15-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold365size193989-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" maker-scaffold13size1375079-augustus-gene-5.1-mRNA-1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" maker-scaffold38size924328-augustus-gene-2.2-mRNA-1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" maker-scaffold382size176025-augustus-gene-0.7-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold12size1412574-augustus-gene-13.22-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold1098size28945-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-1362409;MetaCyc: PWY-7250;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7 "Mitochondrial iron-sulfur cluster biogenesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism" maker-scaffold256size285501-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold5116size3093-augustus-gene-0.1-mRNA-1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway" maker-scaffold16size1255579-augustus-gene-8.10-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold189size362018-augustus-gene-2.0-mRNA-1 4 Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75 "tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis" maker-scaffold603size77277-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" augustus-scaffold430size141210-processed-gene-0.1-mRNA-1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" maker-scaffold120size483217-augustus-gene-2.0-mRNA-1 7 MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7 "Justicidin B biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis" maker-scaffold1401size20169-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" maker-scaffold96size574823-augustus-gene-4.0-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold8size1945031-augustus-gene-7.8-mRNA-1 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685 "Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy" maker-scaffold58size769326-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold311size229472-augustus-gene-1.4-mRNA-1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" maker-scaffold135size449244-augustus-gene-3.1-mRNA-1 6 Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" maker-scaffold6063size9020-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" maker-scaffold397size365563-augustus-gene-2.1-mRNA-1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" maker-scaffold349size205196-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold231size308180-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold100size555673-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold666size61606-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" maker-scaffold37size976698-augustus-gene-0.2-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold72size687670-augustus-gene-3.15-mRNA-1 18 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6783310;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Fanconi Anemia Pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Selenocysteine synthesis" maker-scaffold399size161796-augustus-gene-0.8-mRNA-1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "Separation of Sister Chromatids";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" maker-scaffold136size447168-augustus-gene-0.6-mRNA-1 7 MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" maker-scaffold2447size15112-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" maker-scaffold3605size9757-augustus-gene-0.0-mRNA-1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" maker-scaffold403size154898-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold2606size19995-augustus-gene-0.5-mRNA-1 6 KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"Sphingolipid metabolism" maker-scaffold14size1670589-augustus-gene-15.5-mRNA-1 5 Reactome: R-HSA-189451;MetaCyc: PWY-7159;MetaCyc: PWY-7766;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531 "Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)" maker-scaffold186size363481-augustus-gene-2.3-mRNA-1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" maker-scaffold2206size10871-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold156size419509-augustus-gene-3.10-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold48size811354-augustus-gene-4.12-mRNA-1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" maker-scaffold71size686415-augustus-gene-2.3-mRNA-1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" maker-scaffold19size1242042-augustus-gene-11.16-mRNA-1 2 Reactome: R-HSA-166665;Reactome: R-HSA-977606 "Terminal pathway of complement";"Regulation of Complement cascade" maker-scaffold364size352455-augustus-gene-2.4-mRNA-1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" maker-scaffold2439size9647-augustus-gene-0.1-mRNA-1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" maker-scaffold3879size4662-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold78size655360-augustus-gene-5.24-mRNA-1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" maker-scaffold78size655360-augustus-gene-5.21-mRNA-1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" maker-scaffold86size613819-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" maker-scaffold1size2756217-augustus-gene-6.2-mRNA-1 13 Reactome: R-HSA-532668;Reactome: R-HSA-110320;Reactome: R-HSA-8876725;Reactome: R-HSA-5362768;Reactome: R-HSA-9646399;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-5689896;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Translesion Synthesis by POLH";"Protein methylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Aggrephagy";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"Ovarian tumor domain proteases";"Neutrophil degranulation";"ABC-family proteins mediated transport";"HSF1 activation";"Hedgehog ligand biogenesis";"Josephin domain DUBs" maker-scaffold1size2756217-augustus-gene-21.0-mRNA-1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" maker-scaffold73size681921-augustus-gene-5.6-mRNA-1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" maker-scaffold2size2657229-augustus-gene-6.4-mRNA-1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" augustus-scaffold1580size17182-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold416size148305-augustus-gene-0.0-mRNA-1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" maker-scaffold14size1670589-augustus-gene-12.4-mRNA-1 10 MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8055 "Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis" maker-scaffold108size522426-augustus-gene-4.0-mRNA-1 33 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-69202;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-69273;Reactome: R-HSA-69231 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Cyclin E associated events during G1/S transition";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1" augustus-scaffold1050size30914-processed-gene-0.0-mRNA-1 24 MetaCyc: PWY-7193;KEGG: 00550+1.3.1.98;MetaCyc: PWY-2942;KEGG: 00240+2.7.1.48;Reactome: R-HSA-3359475;Reactome: R-HSA-73614;Reactome: R-HSA-3359478;KEGG: 00261+1.17.1.8;Reactome: R-HSA-196741;MetaCyc: PWY-6386;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00520+1.3.1.98;MetaCyc: PWY-6987;MetaCyc: PWY-5097;MetaCyc: PWY-7382;MetaCyc: PWY-7953;KEGG: 00300+1.17.1.8;MetaCyc: PWY-2941;Reactome: R-HSA-389661;Reactome: R-HSA-71032;MetaCyc: PWY-6387;KEGG: 00785+2.8.1.8;KEGG: 00983+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Peptidoglycan biosynthesis";"L-lysine biosynthesis III";"Pyrimidine metabolism";"Defective MMAA causes methylmalonic aciduria type cblA";"Pyrimidine salvage";"Defective MUT causes methylmalonic aciduria mut type";"Monobactam biosynthesis";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"Gluconeogenesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"L-lysine biosynthesis VI";"Lipoate biosynthesis and incorporation IV (yeast)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Lysine biosynthesis";"L-lysine biosynthesis II";"Glyoxylate metabolism and glycine degradation";"Propionyl-CoA catabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"Lipoic acid metabolism";"Drug metabolism - other enzymes" augustus-scaffold1684size15996-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold104size538128-augustus-gene-1.1-mRNA-1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" maker-scaffold140size439629-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" maker-scaffold87size608750-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6791226 "Neutrophil degranulation";"Major pathway of rRNA processing in the nucleolus and cytosol" augustus-scaffold1002size33106-processed-gene-0.1-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold232size307321-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold17size1249603-augustus-gene-11.3-mRNA-1 5 Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Trafficking and processing of endosomal TLR";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Neutrophil degranulation";"MHC class II antigen presentation" maker-scaffold53size789746-augustus-gene-1.4-mRNA-1 4 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" maker-scaffold47size1319914-augustus-gene-9.3-mRNA-1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" maker-scaffold22size1201825-augustus-gene-11.9-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold572size84276-augustus-gene-0.2-mRNA-1 8 Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-68952 "Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"DNA replication initiation" maker-scaffold6277size9588-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" maker-scaffold154size420078-augustus-gene-3.10-mRNA-1 5 Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" augustus-scaffold1980size12829-processed-gene-0.1-mRNA-1 5 MetaCyc: PWY-6897;MetaCyc: PWY-6893;KEGG: 00730+2.7.4.16;MetaCyc: PWY-6894;MetaCyc: PWY-6896 "Thiamine salvage II";"Thiamine diphosphate biosynthesis II (Bacillus)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis I (E. coli)";"Thiamine salvage I" maker-scaffold471size124115-augustus-gene-0.1-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold22size1201825-augustus-gene-4.28-mRNA-1 6 KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane" augustus-scaffold617size72668-processed-gene-0.1-mRNA-1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)" maker-scaffold6size1916839-augustus-gene-4.2-mRNA-1 10 MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7112 "Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification" maker-scaffold42size1661181-augustus-gene-1.0-mRNA-1 24 Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-428930;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-432040 "G-protein activation";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"G alpha (q) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins" maker-scaffold2size2657229-augustus-gene-25.23-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold2326size16321-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold423size145723-augustus-gene-0.5-mRNA-1 3 Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394 "UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER" maker-scaffold1075size29808-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" augustus-scaffold150size559075-processed-gene-4.1-mRNA-1 45 Reactome: R-HSA-611105;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-5895;MetaCyc: PWY-4381;Reactome: R-HSA-6798695;MetaCyc: PWYG-321;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5844;MetaCyc: PWY-5265;MetaCyc: PWY-7176;MetaCyc: PWY-5789;MetaCyc: PWY-6470;Reactome: R-HSA-4085001;MetaCyc: PWY-6728;MetaCyc: PWY-5743;Reactome: R-HSA-5628897;MetaCyc: PWY-1269;KEGG: 00280+6.4.1.3;Reactome: R-HSA-204174;KEGG: 00630+6.4.1.3;KEGG: 00550+2.7.8.13;MetaCyc: PWY-5744;MetaCyc: PWY-7177;Reactome: R-HSA-1268020;MetaCyc: PWY-6722;MetaCyc: PWY-5849;Reactome: R-HSA-3371599;Reactome: R-HSA-196757;Reactome: R-HSA-8869496;KEGG: 00540+2.7.7.38;Reactome: R-HSA-196780;Reactome: R-HSA-2142789;Reactome: R-HSA-5362517;KEGG: 00240+6.3.4.2;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5839;MetaCyc: PWY-6471;KEGG: 00640+6.4.1.3;MetaCyc: PWY-7384;KEGG: 00720+6.4.1.3;MetaCyc: PWY-5890;Reactome: R-HSA-71032 "Respiratory electron transport";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Menaquinol-13 biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Neutrophil degranulation";"";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-9 biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"UTP and CTP de novo biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Sialic acid metabolism";"Methylaspartate cycle";"3-hydroxypropanoate cycle";"TP53 Regulates Metabolic Genes";"CMP-3-deoxy-D-manno-octulosonate biosynthesis";"Valine, leucine and isoleucine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate and dicarboxylate metabolism";"Peptidoglycan biosynthesis";"Glyoxylate assimilation";"UTP and CTP dephosphorylation II";"Mitochondrial protein import";"Candicidin biosynthesis";"Menaquinol-6 biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Metabolism of folate and pterines";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Lipopolysaccharide biosynthesis";"Biotin transport and metabolism";"Ubiquinol biosynthesis";"Signaling by Retinoic Acid";"Pyrimidine metabolism";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Menaquinol-10 biosynthesis";"Propionyl-CoA catabolism" maker-scaffold142size437600-augustus-gene-3.0-mRNA-1 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" maker-scaffold218size326752-augustus-gene-2.13-mRNA-1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-6598 "Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis" maker-scaffold1766size15073-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" maker-scaffold183size369409-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" augustus-scaffold1000size33131-processed-gene-0.0-mRNA-1 6 Reactome: R-HSA-196807;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;KEGG: 00760+6.3.1.5;KEGG: 00970+6.1.1.10 "Nicotinate metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Nicotinate and nicotinamide metabolism";"Aminoacyl-tRNA biosynthesis" maker-scaffold9size1444705-augustus-gene-4.19-mRNA-1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" maker-scaffold50size801739-augustus-gene-5.1-mRNA-1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" maker-scaffold29size1057726-augustus-gene-6.1-mRNA-1 4 MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20 "Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism" maker-scaffold18size2240851-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold16size1255579-augustus-gene-6.4-mRNA-1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" augustus-scaffold1327size21525-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00260+2.3.1.37 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Glycine, serine and threonine metabolism" maker-scaffold30size1054049-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-1442490;Reactome: R-HSA-1474228 "Collagen degradation";"Degradation of the extracellular matrix" maker-scaffold16size1255579-augustus-gene-6.1-mRNA-1 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold242size299879-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" maker-scaffold1536size17960-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" maker-scaffold573size83708-augustus-gene-0.0-mRNA-1 4 KEGG: 00250+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" maker-scaffold1695size16062-augustus-gene-0.0-mRNA-1 11 Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-72163;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"mRNA Splicing - Major Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling" maker-scaffold6500size7093-augustus-gene-0.0-mRNA-1 24 Reactome: R-HSA-381676;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-392170;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (s) signalling events";"G-protein activation";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 12";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling" maker-scaffold2703size8470-augustus-gene-0.0-mRNA-1 8 Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962 "Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex" maker-scaffold1size2756217-augustus-gene-15.1-mRNA-1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" maker-scaffold280size266829-augustus-gene-0.1-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold136size447168-augustus-gene-3.6-mRNA-1 14 MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" maker-scaffold89size602897-augustus-gene-5.2-mRNA-1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" maker-scaffold4size1754260-augustus-gene-7.1-mRNA-1 16 Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-8853884 "Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX" maker-scaffold7size1668642-augustus-gene-15.2-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold120size483217-augustus-gene-3.13-mRNA-1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold80size1421260-augustus-gene-2.1-mRNA-1 13 MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-2024101 "Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"CS/DS degradation" maker-scaffold21size1197050-augustus-gene-8.7-mRNA-1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" maker-scaffold80size1421260-augustus-gene-13.0-mRNA-1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" maker-scaffold5702size2904-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" maker-scaffold382size176025-augustus-gene-0.8-mRNA-1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" maker-scaffold318size381727-augustus-gene-2.7-mRNA-1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" maker-scaffold31size1053862-augustus-gene-7.0-mRNA-1 3 Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport" maker-scaffold643size65972-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" maker-scaffold1450size19431-augustus-gene-0.0-mRNA-1 6 MetaCyc: PWY-4381;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5743 "Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate cycle" maker-scaffold21size1197050-augustus-gene-5.6-mRNA-1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" maker-scaffold34size991984-augustus-gene-9.12-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold223size319359-augustus-gene-1.0-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" augustus-scaffold1007size32759-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold92size586643-augustus-gene-4.11-mRNA-1 9 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-2173796;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362300 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" maker-scaffold320size221394-augustus-gene-1.7-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold1size2756217-augustus-gene-26.13-mRNA-1 3 Reactome: R-HSA-190873;Reactome: R-HSA-399719;Reactome: R-HSA-156588 "Gap junction degradation";"Trafficking of AMPA receptors";"Glucuronidation" maker-scaffold17size1249603-augustus-gene-8.0-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold554size88319-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold5size1727520-augustus-gene-8.15-mRNA-1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" maker-scaffold13size1375079-augustus-gene-6.4-mRNA-1 5 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1" maker-scaffold457size129484-augustus-gene-0.2-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold174size395000-augustus-gene-0.0-mRNA-1 24 Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-416482 "G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"G alpha (q) signalling events";"G-protein activation";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events" maker-scaffold14size1670589-augustus-gene-12.8-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold13size1375079-augustus-gene-7.5-mRNA-1 12 MetaCyc: PWY-6978;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5870;Reactome: R-HSA-1268020;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;MetaCyc: PWY-5872 "Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)" maker-scaffold8size1945031-augustus-gene-15.5-mRNA-1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"mTOR signalling";"HSF1-dependent transactivation";"Macroautophagy";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" maker-scaffold13size1375079-augustus-gene-5.6-mRNA-1 5 MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiamine metabolism";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis" maker-scaffold276size261909-augustus-gene-1.5-mRNA-1 8 Reactome: R-HSA-425561;Reactome: R-HSA-5693579;Reactome: R-HSA-418359;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5578775;Reactome: R-HSA-5685942;Reactome: R-HSA-912446 "Sodium/Calcium exchangers";"Homologous DNA Pairing and Strand Exchange";"Reduction of cytosolic Ca++ levels";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Ion homeostasis";"HDR through Homologous Recombination (HRR)";"Meiotic recombination" maker-scaffold80size1421260-augustus-gene-5.2-mRNA-1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-382556;Reactome: R-HSA-5678771 "PPARA activates gene expression";"ABC-family proteins mediated transport";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1" augustus-scaffold1727size15532-processed-gene-0.0-mRNA-1 8 KEGG: 00750+2.6.1.52;MetaCyc: PWY-7723;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00073+1.2.1.50 "Vitamin B6 metabolism";"Bacterial bioluminescence";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Methane metabolism";"Glycine, serine and threonine metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold9size1444705-augustus-gene-13.1-mRNA-1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" maker-scaffold10size1426409-augustus-gene-9.3-mRNA-1 56 Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-450408 "Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA" maker-scaffold209size335547-augustus-gene-2.5-mRNA-1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" maker-scaffold1252size23155-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange" maker-scaffold260size277064-augustus-gene-1.11-mRNA-1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" maker-scaffold169size953240-augustus-gene-3.4-mRNA-1 10 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-75955;KEGG: 00190+7.1.2.2;Reactome: R-HSA-112382;Reactome: R-HSA-2151201;MetaCyc: PWY-7980;Reactome: R-HSA-674695 "Mitochondrial protein import";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"RNA Polymerase II Transcription Elongation";"Oxidative phosphorylation";"Formation of RNA Pol II elongation complex";"Transcriptional activation of mitochondrial biogenesis";"ATP biosynthesis";"RNA Polymerase II Pre-transcription Events" maker-scaffold210size338753-augustus-gene-2.23-mRNA-1 8 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5173105 "Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"O-linked glycosylation" augustus-scaffold2632size8804-processed-gene-0.1-mRNA-1 4 Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6 "Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold65size703589-augustus-gene-6.6-mRNA-1 5 KEGG: 00350+1.13.11.5;MetaCyc: PWY-5386;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00620+3.1.2.6 "Tyrosine metabolism";"Methylglyoxal degradation I";"Styrene degradation";"Tyrosine catabolism";"Pyruvate metabolism" maker-scaffold869size42088-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold12size1412574-augustus-gene-13.3-mRNA-1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" maker-scaffold210size338753-augustus-gene-2.7-mRNA-1 7 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" maker-scaffold522size99678-augustus-gene-0.12-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold70size694644-augustus-gene-5.6-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold271size267669-augustus-gene-1.1-mRNA-1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine" maker-scaffold2size2657229-augustus-gene-25.19-mRNA-1 5 Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-190873 "Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation" maker-scaffold468size124502-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-195399;Reactome: R-HSA-216083;Reactome: R-HSA-5218921;Reactome: R-HSA-194306;Reactome: R-HSA-4420097 "VEGF binds to VEGFR leading to receptor dimerization";"Integrin cell surface interactions";"VEGFR2 mediated cell proliferation";"Neurophilin interactions with VEGF and VEGFR";"VEGFA-VEGFR2 Pathway" maker-scaffold948size36209-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" maker-scaffold436size138428-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" maker-scaffold730size53482-augustus-gene-0.4-mRNA-1 12 Reactome: R-HSA-3214847;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856 "HATs acetylate histones";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling" maker-scaffold25size1130848-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" maker-scaffold26size1667613-augustus-gene-12.4-mRNA-1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" maker-scaffold197size348675-augustus-gene-2.1-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" augustus-scaffold1063size30137-processed-gene-0.0-mRNA-1 10 Reactome: R-HSA-1989781;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-922 "PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate pathway I" maker-scaffold26size1667613-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-611105 "Respiratory electron transport" maker-scaffold72size687670-augustus-gene-3.13-mRNA-1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling" maker-scaffold2size2657229-augustus-gene-1.4-mRNA-1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold1071size29910-augustus-gene-0.0-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold37size976698-augustus-gene-6.5-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold100size555673-augustus-gene-1.2-mRNA-1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" maker-scaffold1691size24806-augustus-gene-0.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold38size924328-augustus-gene-3.2-mRNA-1 13 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-2022090;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Assembly of collagen fibrils and other multimeric structures";"Laminin interactions";"Extracellular matrix organization";"NCAM1 interactions";"ECM proteoglycans";"Signaling by PDGF";"Integrin cell surface interactions";"Non-integrin membrane-ECM interactions";"Collagen degradation" maker-scaffold181size378167-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5617833 "Cilium Assembly" maker-scaffold4size1754260-augustus-gene-4.10-mRNA-1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" maker-scaffold3size2782310-augustus-gene-15.3-mRNA-1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" maker-scaffold80size1421260-augustus-gene-5.0-mRNA-1 3 Reactome: R-HSA-5678771;Reactome: R-HSA-382556;Reactome: R-HSA-1989781 "Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"ABC-family proteins mediated transport";"PPARA activates gene expression" maker-scaffold70size694644-augustus-gene-3.7-mRNA-1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" maker-scaffold79size709353-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold12size1412574-augustus-gene-7.0-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" maker-scaffold269size268280-augustus-gene-0.4-mRNA-1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" maker-scaffold193size358747-augustus-gene-1.8-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold36size1013817-augustus-gene-9.3-mRNA-1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "SRP-dependent cotranslational protein targeting to membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold105size529344-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold36size1013817-augustus-gene-9.4-mRNA-1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "HATs acetylate histones";"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" maker-scaffold43size857109-augustus-gene-4.6-mRNA-1 5 Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" maker-scaffold145size712617-augustus-gene-2.3-mRNA-1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" maker-scaffold192size359585-augustus-gene-2.1-mRNA-1 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927 "TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3" maker-scaffold180size376838-augustus-gene-1.8-mRNA-1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" maker-scaffold1size2756217-augustus-gene-1.3-mRNA-1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" maker-scaffold165size402902-augustus-gene-2.0-mRNA-1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" maker-scaffold130size553940-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" maker-scaffold73size681921-augustus-gene-5.8-mRNA-1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" maker-scaffold8size1945031-augustus-gene-4.20-mRNA-1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" maker-scaffold385size173139-augustus-gene-0.1-mRNA-1 4 MetaCyc: PWY-7494;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163 "Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline catabolism" maker-scaffold220size322609-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" maker-scaffold5863size2854-augustus-gene-0.1-mRNA-1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" maker-scaffold9size1444705-augustus-gene-4.4-mRNA-1 3 Reactome: R-HSA-5678771;Reactome: R-HSA-1989781;Reactome: R-HSA-382556 "Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression";"ABC-family proteins mediated transport" maker-scaffold5size1727520-augustus-gene-9.1-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold10size1426409-augustus-gene-11.8-mRNA-1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" maker-scaffold20size1234842-augustus-gene-7.2-mRNA-1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" maker-scaffold836size43607-augustus-gene-0.0-mRNA-1 28 Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-72163;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-4615885;Reactome: R-HSA-5685942;Reactome: R-HSA-8866654;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-72165;Reactome: R-HSA-6804114;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-1362277;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-174437;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-69205;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5358606 "Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"mRNA Splicing - Major Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"SUMOylation of DNA replication proteins";"HDR through Homologous Recombination (HRR)";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Transcription of E2F targets under negative control by DREAM complex";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate from the C-strand";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" maker-scaffold1size2756217-augustus-gene-6.0-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold1879size21166-augustus-gene-0.1-mRNA-1 11 MetaCyc: PWY-6549;MetaCyc: PWY-5675;Reactome: R-HSA-8964539;MetaCyc: PWY-381;KEGG: 00250+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-6964;Reactome: R-HSA-210455;KEGG: 00630+6.3.1.2 "L-glutamine biosynthesis III";"Nitrate reduction V (assimilatory)";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Glyoxylate and dicarboxylate metabolism" maker-scaffold59size767954-augustus-gene-6.6-mRNA-1 3 Reactome: R-HSA-204174;Reactome: R-HSA-70895;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Branched-chain amino acid catabolism";"Signaling by Retinoic Acid" maker-scaffold33size1007119-augustus-gene-8.7-mRNA-1 11 KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6549;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268 "Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" maker-scaffold586size100906-augustus-gene-0.3-mRNA-1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6 "Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism" maker-scaffold11size1424826-augustus-gene-5.1-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold55size783029-augustus-gene-1.5-mRNA-1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" maker-scaffold24size1136029-augustus-gene-9.5-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold59size767954-augustus-gene-3.7-mRNA-1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" maker-scaffold227size314013-augustus-gene-1.6-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold2size2657229-augustus-gene-15.0-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold48size811354-augustus-gene-6.0-mRNA-1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" maker-scaffold143size433092-augustus-gene-3.3-mRNA-1 19 Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423 "Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"LDL remodeling";"Scavenging by Class A Receptors";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron assembly";"Post-translational protein phosphorylation";"VLDL assembly" maker-scaffold4size1754260-augustus-gene-16.12-mRNA-1 7 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" maker-scaffold176size389526-augustus-gene-2.2-mRNA-1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" maker-scaffold5size1727520-augustus-gene-11.4-mRNA-1 6 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-9640463;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Wax biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold8size1945031-augustus-gene-2.3-mRNA-1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" maker-scaffold84size638750-augustus-gene-4.15-mRNA-1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" maker-scaffold54size1273868-augustus-gene-11.5-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-196783 "COPI-dependent Golgi-to-ER retrograde traffic";"Coenzyme A biosynthesis" maker-scaffold227size314013-augustus-gene-2.5-mRNA-1 10 MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)" maker-scaffold34size991984-augustus-gene-3.6-mRNA-1 26 Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-389960 "Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC" maker-scaffold5size1727520-augustus-gene-16.4-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold280size266829-augustus-gene-1.0-mRNA-1 5 Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619 "2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN" maker-scaffold25size1130848-augustus-gene-5.5-mRNA-1 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism" maker-scaffold599size78611-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold83size640441-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-71384 "Ethanol oxidation" maker-scaffold2size2657229-augustus-gene-25.8-mRNA-1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response" augustus-scaffold2197size10965-processed-gene-0.0-mRNA-1 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" maker-scaffold100size555673-augustus-gene-3.7-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold504size105914-augustus-gene-0.3-mRNA-1 8 MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6;Reactome: R-HSA-5659996;Reactome: R-HSA-6791461;KEGG: 00710+5.3.1.6;KEGG: 00051+5.3.1.6 "Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway";"RPIA deficiency: failed conversion of R5P to RU5P";"RPIA deficiency: failed conversion of RU5P to R5P";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism" maker-scaffold383size174942-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold268size268435-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-71288 "Creatine metabolism" maker-scaffold3882size11229-augustus-gene-0.2-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)" maker-scaffold26size1667613-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" maker-scaffold5814size2870-augustus-gene-0.1-mRNA-1 3 KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis" maker-scaffold223size319359-augustus-gene-2.4-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression" maker-scaffold354size203655-augustus-gene-1.2-mRNA-1 13 MetaCyc: PWY-2161;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-2201;MetaCyc: PWY-7909;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-3841;Reactome: R-HSA-196757 "Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Metabolism of folate and pterines" maker-scaffold14size1670589-augustus-gene-1.1-mRNA-1 7 MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" maker-scaffold21size1197050-augustus-gene-10.2-mRNA-1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" maker-scaffold39size909063-augustus-gene-8.3-mRNA-1 9 MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" maker-scaffold42size1661181-augustus-gene-13.0-mRNA-1 4 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism" maker-scaffold52size909272-augustus-gene-8.6-mRNA-1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" maker-scaffold87size608750-augustus-gene-1.4-mRNA-1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" maker-scaffold4size1754260-augustus-gene-4.4-mRNA-1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-8951664 "Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Neddylation" maker-scaffold8size1945031-augustus-gene-13.9-mRNA-1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold282size258062-augustus-gene-1.6-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold34size991984-augustus-gene-6.1-mRNA-1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" maker-scaffold180size376838-augustus-gene-1.3-mRNA-1 11 MetaCyc: PWY-5943;MetaCyc: PWY-5947;MetaCyc: PWY-7939;MetaCyc: PWY-7947;Reactome: R-HSA-191273;MetaCyc: PWY-7938;Reactome: R-HSA-1989781;MetaCyc: PWY-6279;KEGG: 00906+2.5.1.32+5.5.1.19;MetaCyc: PWY-7591;Reactome: R-HSA-2426168 "Beta-carotene biosynthesis";"Lutein biosynthesis";"Chlorobactene biosynthesis";"Flexixanthin biosynthesis";"Cholesterol biosynthesis";"Isorenieratene biosynthesis I (actinobacteria)";"PPARA activates gene expression";"Myxol-2' fucoside biosynthesis";"Carotenoid biosynthesis";"Okenone biosynthesis";"Activation of gene expression by SREBF (SREBP)" maker-scaffold65size703589-augustus-gene-6.5-mRNA-1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-445355 "Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Smooth Muscle Contraction" maker-scaffold49size896674-augustus-gene-5.0-mRNA-1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" maker-scaffold121size481755-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" maker-scaffold281size259073-augustus-gene-1.6-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" maker-scaffold1447size19484-augustus-gene-0.1-mRNA-1 57 Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-532668;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" maker-scaffold24size1136029-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold261size276640-augustus-gene-0.3-mRNA-1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" maker-scaffold1717size15659-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" maker-scaffold3size2782310-augustus-gene-8.0-mRNA-1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" maker-scaffold6393size2703-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold26size1667613-augustus-gene-15.3-mRNA-1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" maker-scaffold15907size7919-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis" maker-scaffold36size1013817-augustus-gene-9.8-mRNA-1 12 Reactome: R-HSA-73817;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6122 "Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism";"Purine metabolism";"Purine metabolism";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis I";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"5-aminoimidazole ribonucleotide biosynthesis II" maker-scaffold87size608750-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" maker-scaffold6788size13373-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-5620922 "tRNA modification in the nucleus and cytosol";"BBSome-mediated cargo-targeting to cilium" maker-scaffold1size2756217-augustus-gene-13.11-mRNA-1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" maker-scaffold13size1375079-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" maker-scaffold86size613819-augustus-gene-3.14-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold18212size7325-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" maker-scaffold37size976698-augustus-gene-3.8-mRNA-1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" maker-scaffold99size561911-augustus-gene-4.8-mRNA-1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" maker-scaffold2size2657229-augustus-gene-12.0-mRNA-1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" maker-scaffold2size2657229-augustus-gene-14.2-mRNA-1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" maker-scaffold72size687670-augustus-gene-3.12-mRNA-1 11 Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-1250196;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-5673001 "PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"RAF/MAP kinase cascade" maker-scaffold1025size31985-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" maker-scaffold288size250223-augustus-gene-1.1-mRNA-1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017 "Neutrophil degranulation";"Peroxisomal protein import";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" maker-scaffold17size1249603-augustus-gene-10.1-mRNA-1 4 KEGG: 00970+6.1.1.7;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Aminoacyl-tRNA biosynthesis";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" maker-scaffold6size1916839-augustus-gene-13.8-mRNA-1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" maker-scaffold21538size7480-augustus-gene-0.1-mRNA-1 5 KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409 "T cell receptor signaling pathway";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation" maker-scaffold17size1249603-augustus-gene-5.1-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" augustus-scaffold1017size32228-processed-gene-0.0-mRNA-1 10 Reactome: R-HSA-2644606;Reactome: R-HSA-1362409;Reactome: R-HSA-350054;Reactome: R-HSA-211976;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Mitochondrial iron-sulfur cluster biogenesis";"Notch-HLH transcription pathway";"Endogenous sterols";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" maker-scaffold1size2756217-augustus-gene-8.1-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold5size1727520-augustus-gene-4.8-mRNA-1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" maker-scaffold19size1242042-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold248size292329-augustus-gene-1.13-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold42size1661181-augustus-gene-13.5-mRNA-1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" maker-scaffold161size412613-augustus-gene-3.11-mRNA-1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" maker-scaffold54size1273868-augustus-gene-9.7-mRNA-1 1 Reactome: R-HSA-1483255 "PI Metabolism" maker-scaffold782size48773-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-6804115;Reactome: R-HSA-5419276;Reactome: R-HSA-429947;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Mitochondrial translation termination";"Deadenylation of mRNA";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold23size1161859-augustus-gene-5.7-mRNA-1 9 Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway" maker-scaffold14size1670589-augustus-gene-6.4-mRNA-1 14 Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes" maker-scaffold266size269306-augustus-gene-1.8-mRNA-1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" maker-scaffold9827size7729-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" maker-scaffold85size629767-augustus-gene-5.4-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold11size1424826-augustus-gene-6.1-mRNA-1 5 MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768 "Protein ubiquitination";"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" maker-scaffold1467size25699-augustus-gene-0.3-mRNA-1 9 Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400 "Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER" maker-scaffold254size288410-augustus-gene-1.9-mRNA-1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" maker-scaffold1size2756217-augustus-gene-4.21-mRNA-1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" maker-scaffold5281size7691-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" maker-scaffold8size1945031-augustus-gene-15.1-mRNA-1 21 MetaCyc: PWY-7210;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-6545;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7224;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7219;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"CMP phosphorylation";"Adenosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" maker-scaffold8055size14238-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1" maker-scaffold19size1242042-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" maker-scaffold58size769326-augustus-gene-4.0-mRNA-1 9 Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253 "Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" maker-scaffold526size170922-augustus-gene-0.11-mRNA-1 4 Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "G alpha (i) signalling events";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN" maker-scaffold241size304314-augustus-gene-2.1-mRNA-1 15 Reactome: R-HSA-167290;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-2173796 "Pausing and recovery of HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" maker-scaffold22size1201825-augustus-gene-7.4-mRNA-1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" maker-scaffold26size1667613-augustus-gene-5.6-mRNA-1 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" maker-scaffold18size2240851-augustus-gene-3.0-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold364size352455-augustus-gene-2.8-mRNA-1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold84size638750-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" augustus-scaffold2488size9433-processed-gene-0.0-mRNA-1 10 KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-7003;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis" maker-scaffold76size663279-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" maker-scaffold6size1916839-augustus-gene-14.5-mRNA-1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" maker-scaffold238size302402-augustus-gene-2.18-mRNA-1 9 MetaCyc: PWY-7391;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;KEGG: 00510+2.4.1.267;MetaCyc: PWY-922;Reactome: R-HSA-446193;Reactome: R-HSA-191273;Reactome: R-HSA-4724289 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"N-Glycan biosynthesis";"Mevalonate pathway I";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Cholesterol biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)" maker-scaffold29size1057726-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" maker-scaffold45size832949-augustus-gene-6.2-mRNA-1 15 MetaCyc: PWY-6886;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-5723;MetaCyc: PWY-6901;Reactome: R-HSA-70171 "1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Glycolysis" maker-scaffold552size88858-augustus-gene-0.0-mRNA-1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" maker-scaffold8size1945031-augustus-gene-4.19-mRNA-1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" maker-scaffold10size1426409-augustus-gene-13.1-mRNA-1 1 Reactome: R-HSA-1483166 "Synthesis of PA" maker-scaffold912size38152-augustus-gene-0.0-mRNA-1 5 KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-425410;Reactome: R-HSA-390247 "beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"Metal ion SLC transporters";"Beta-oxidation of very long chain fatty acids" augustus-scaffold857size42128-processed-gene-0.0-mRNA-1 6 Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import" maker-scaffold573size83708-augustus-gene-0.3-mRNA-1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-2151201 "RORA activates gene expression";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis" maker-scaffold307size231700-augustus-gene-1.1-mRNA-1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" maker-scaffold8size1945031-augustus-gene-3.2-mRNA-1 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177 "Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II" maker-scaffold104size538128-augustus-gene-3.2-mRNA-1 8 KEGG: 00906+2.5.1.32+5.5.1.19;MetaCyc: PWY-6279;MetaCyc: PWY-7591;MetaCyc: PWY-7939;MetaCyc: PWY-5947;MetaCyc: PWY-5943;MetaCyc: PWY-7938;MetaCyc: PWY-7947 "Carotenoid biosynthesis";"Myxol-2' fucoside biosynthesis";"Okenone biosynthesis";"Chlorobactene biosynthesis";"Lutein biosynthesis";"Beta-carotene biosynthesis";"Isorenieratene biosynthesis I (actinobacteria)";"Flexixanthin biosynthesis" maker-scaffold26size1667613-augustus-gene-6.3-mRNA-1 5 MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072;Reactome: R-HSA-8849175 "Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization";"Threonine catabolism" maker-scaffold32size1041436-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold79size709353-augustus-gene-5.2-mRNA-1 6 Reactome: R-HSA-3299685;Reactome: R-HSA-499943;Reactome: R-HSA-5628897;MetaCyc: PWY-4081;Reactome: R-HSA-2408550;KEGG: 00480+1.8.1.7 "Detoxification of Reactive Oxygen Species";"Interconversion of nucleotide di- and triphosphates";"TP53 Regulates Metabolic Genes";"Glutathione-peroxide redox reactions";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Glutathione metabolism" maker-scaffold1574size17290-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-450385 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" maker-scaffold92size586643-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" maker-scaffold21size1197050-augustus-gene-10.4-mRNA-1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" maker-scaffold84size638750-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" maker-scaffold489size113917-augustus-gene-0.2-mRNA-1 1 MetaCyc: PWY-7379 "Mrna capping II" maker-scaffold17size1249603-augustus-gene-9.1-mRNA-1 52 Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-180534 "Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Downstream TCR signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4" augustus-scaffold2244size10577-processed-gene-0.0-mRNA-1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.18 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold22size1201825-augustus-gene-7.3-mRNA-1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" maker-scaffold11size1424826-augustus-gene-9.4-mRNA-1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" maker-scaffold514size105244-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" maker-scaffold3207size10892-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold646size65642-augustus-gene-0.0-mRNA-1 40 Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-167243;Reactome: R-HSA-76042;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-203927 "mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis" maker-scaffold3size2782310-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" maker-scaffold191size643645-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold12size1412574-augustus-gene-13.17-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold34size991984-augustus-gene-3.4-mRNA-1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" maker-scaffold24size1136029-augustus-gene-7.4-mRNA-1 7 Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis" maker-scaffold1size2756217-augustus-gene-16.4-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold87size608750-augustus-gene-5.2-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold546size91324-augustus-gene-0.10-mRNA-1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" augustus-scaffold2430size9671-processed-gene-0.0-mRNA-1 17 Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-3270619;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-1834949;Reactome: R-HSA-69473 "Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"IRF3-mediated induction of type I IFN";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Cytosolic sensors of pathogen-associated DNA";"G2/M DNA damage checkpoint" maker-scaffold1018size32227-augustus-gene-0.1-mRNA-1 7 Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;MetaCyc: PWY-5188 "Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Tetrapyrrole biosynthesis I (from glutamate)" maker-scaffold89size602897-augustus-gene-5.21-mRNA-1 5 KEGG: 00640+1.2.4.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;Reactome: R-HSA-70895;KEGG: 00280+1.2.4.4 "Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" maker-scaffold84size638750-augustus-gene-5.11-mRNA-1 27 Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3301854 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly" maker-scaffold78size655360-augustus-gene-1.3-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" maker-scaffold255size285696-augustus-gene-1.1-mRNA-1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-6811558;Reactome: R-HSA-5467348 "RAF activation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Truncations of AMER1 destabilize the destruction complex" maker-scaffold64size713537-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" maker-scaffold89size602897-augustus-gene-1.5-mRNA-1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" maker-scaffold169size953240-augustus-gene-8.19-mRNA-1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" maker-scaffold54size1273868-augustus-gene-7.0-mRNA-1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" maker-scaffold50size801739-augustus-gene-7.3-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold80size1421260-augustus-gene-5.3-mRNA-1 3 Reactome: R-HSA-159418;Reactome: R-HSA-5678520;Reactome: R-HSA-193368 "Recycling of bile acids and salts";"Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol" maker-scaffold36size1013817-augustus-gene-1.0-mRNA-1 7 Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane" maker-scaffold176size389526-augustus-gene-1.7-mRNA-1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold2size2657229-augustus-gene-19.7-mRNA-1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" maker-scaffold1878size17949-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold85size629767-augustus-gene-5.9-mRNA-1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" augustus-scaffold1306size21967-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;KEGG: 00770+2.7.1.24;Reactome: R-HSA-1660514;MetaCyc: PWY-7851 "Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Pantothenate and CoA biosynthesis";"Synthesis of PIPs at the Golgi membrane";"Coenzyme A biosynthesis II (eukaryotic)" maker-scaffold296size241411-augustus-gene-0.1-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold3975size22697-augustus-gene-0.2-mRNA-1 9 Reactome: R-HSA-446193;MetaCyc: PWY-6385;MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00513+2.4.1.141;KEGG: 00510+2.4.1.141;MetaCyc: PWY-6471;KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" maker-scaffold147size424191-augustus-gene-2.9-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold6442size8106-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold4size1754260-augustus-gene-4.16-mRNA-1 2 Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" maker-scaffold1size2756217-augustus-gene-7.2-mRNA-1 13 Reactome: R-HSA-201722;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-380994;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-6791226;Reactome: R-HSA-5689880;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385 "Formation of the beta-catenin:TCF transactivating complex";"UCH proteinases";"HATs acetylate histones";"ATF4 activates genes in response to endoplasmic reticulum stress";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ub-specific processing proteases";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" augustus-scaffold279size261100-processed-gene-1.8-mRNA-1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold200size345481-augustus-gene-2.2-mRNA-1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" augustus-scaffold1123size27873-processed-gene-0.1-mRNA-1 17 Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;MetaCyc: PWY-6308;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649 "Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"L-cysteine biosynthesis II (tRNA-dependent)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation" augustus-scaffold1498size18539-processed-gene-0.0-mRNA-1 13 Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745 "MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" maker-scaffold1848size14137-augustus-gene-0.1-mRNA-1 6 Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold6size1916839-augustus-gene-0.3-mRNA-1 5 KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22 "Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Glycerolipid metabolism" maker-scaffold34size991984-augustus-gene-3.18-mRNA-1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" maker-scaffold4size1754260-augustus-gene-9.0-mRNA-1 13 Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52 "Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation" maker-scaffold14size1670589-augustus-gene-15.25-mRNA-1 5 Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" maker-scaffold3993size10272-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" maker-scaffold357size199749-augustus-gene-1.1-mRNA-1 29 Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-76042 "Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"mRNA Capping";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance" maker-scaffold12size1412574-augustus-gene-13.5-mRNA-1 12 Reactome: R-HSA-167243;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167238 "Tat-mediated HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation" maker-scaffold10size1426409-augustus-gene-6.4-mRNA-1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" maker-scaffold1890size13733-augustus-gene-0.0-mRNA-1 13 Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-389357 "PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"mTOR signalling";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"CD28 dependent PI3K/Akt signaling" maker-scaffold10size1426409-augustus-gene-11.3-mRNA-1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" maker-scaffold429size142089-augustus-gene-0.6-mRNA-1 7 MetaCyc: PWY-7790;MetaCyc: PWY-7400;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154 "UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis III";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)" maker-scaffold19size1242042-augustus-gene-2.2-mRNA-1 13 KEGG: 00053+1.8.5.1;MetaCyc: PWY-7533;MetaCyc: PWY-7112;MetaCyc: PWY-2261;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;Reactome: R-HSA-196836;MetaCyc: PWY-6370 "Ascorbate and aldarate metabolism";"Gliotoxin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - other enzymes";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Ascorbate recycling (cytosolic)" maker-scaffold3size2782310-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" maker-scaffold77size662763-augustus-gene-5.24-mRNA-1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" maker-scaffold107size522501-augustus-gene-1.0-mRNA-1 6 Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" maker-scaffold11size1424826-augustus-gene-7.3-mRNA-1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" maker-scaffold1898size13648-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" maker-scaffold238size302402-augustus-gene-0.3-mRNA-1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" maker-scaffold2size2657229-augustus-gene-1.8-mRNA-1 7 MetaCyc: PWY-6122;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6277 "5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" maker-scaffold136size447168-augustus-gene-3.28-mRNA-1 19 Reactome: R-HSA-418885;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-182971 "DCC mediated attractive signaling";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"Myogenesis";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"EGFR downregulation" maker-scaffold3size2782310-augustus-gene-1.2-mRNA-1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" maker-scaffold222size322023-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold4size1754260-augustus-gene-8.0-mRNA-1 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" maker-scaffold821size45251-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" maker-scaffold694size57415-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" maker-scaffold701size56601-augustus-gene-0.1-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" augustus-scaffold2584size8987-processed-gene-0.0-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold3235size6258-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" augustus-scaffold2009size12570-processed-gene-0.0-mRNA-1 23 KEGG: 00860+4.1.1.37;Reactome: R-HSA-9010553;MetaCyc: PWY-7159;Reactome: R-HSA-72764;Reactome: R-HSA-156902;MetaCyc: PWY-7766;Reactome: R-HSA-72689;Reactome: R-HSA-983189;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-189451;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6811434;MetaCyc: PWY-5531;Reactome: R-HSA-72702;Reactome: R-HSA-2408557 "Porphyrin and chlorophyll metabolism";"Regulation of expression of SLITs and ROBOs";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Heme b biosynthesis IV (Gram-positive bacteria)";"Formation of a pool of free 40S subunits";"Kinesins";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Heme biosynthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"COPI-dependent Golgi-to-ER retrograde traffic";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis" maker-scaffold3581size10133-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" maker-scaffold113size504212-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" maker-scaffold9size1444705-augustus-gene-4.14-mRNA-1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" maker-scaffold206size339876-augustus-gene-2.1-mRNA-1 6 Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-9640463;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Wax biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression" maker-scaffold76size663279-augustus-gene-4.9-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold80size1421260-augustus-gene-9.1-mRNA-1 4 KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate" augustus-scaffold654size63491-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold64size713537-augustus-gene-3.0-mRNA-1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" maker-scaffold13size1375079-augustus-gene-11.2-mRNA-1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" maker-scaffold16size1255579-augustus-gene-8.9-mRNA-1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" maker-scaffold26size1667613-augustus-gene-15.2-mRNA-1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" maker-scaffold70size694644-augustus-gene-3.5-mRNA-1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" maker-scaffold246size295413-augustus-gene-2.10-mRNA-1 3 Reactome: R-HSA-6790901;Reactome: R-HSA-8951664;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold146size428850-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold3size2782310-augustus-gene-8.3-mRNA-1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" maker-scaffold252size289391-augustus-gene-1.9-mRNA-1 6 KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series" maker-scaffold446size134571-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold33size1007119-augustus-gene-8.1-mRNA-1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" maker-scaffold16size1255579-augustus-gene-4.12-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold270size268122-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold185size368400-augustus-gene-2.14-mRNA-1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" maker-scaffold154size420078-augustus-gene-3.0-mRNA-1 6 Reactome: R-HSA-3371599;MetaCyc: PWY-7382;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;KEGG: 00780+6.3.4.15 "Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin metabolism" maker-scaffold413size150002-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" maker-scaffold219size326357-augustus-gene-0.0-mRNA-1 1 KEGG: 00500+3.2.1.39 "Starch and sucrose metabolism" maker-scaffold1577size17278-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold23size1161859-augustus-gene-4.0-mRNA-1 14 MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-8041 "(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis" maker-scaffold2size2657229-augustus-gene-25.16-mRNA-1 1 Reactome: R-HSA-114608 "Platelet degranulation" maker-scaffold20size1234842-augustus-gene-8.0-mRNA-1 10 Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-3214847 "HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones" maker-scaffold21size1197050-augustus-gene-8.3-mRNA-1 22 MetaCyc: PWY-3801;MetaCyc: PWY-5384;MetaCyc: PWY-5514;Reactome: R-HSA-6798695;MetaCyc: PWY-6992;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-7238;KEGG: 00500+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-622;KEGG: 00520+5.3.1.9;MetaCyc: PWY-7347;KEGG: 00010+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-6142;MetaCyc: PWY-5054;Reactome: R-HSA-5628897;MetaCyc: PWY-621;MetaCyc: PWY-7385;MetaCyc: PWY-5659;MetaCyc: PWY-6981 "Sucrose degradation II (sucrose synthase)";"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neutrophil degranulation";"1,5-anhydrofructose degradation";"Glycolysis";"Gluconeogenesis";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Pentose phosphate pathway";"Starch biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis III";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"D-sorbitol biosynthesis I";"TP53 Regulates Metabolic Genes";"Sucrose degradation III (sucrose invertase)";"1,3-propanediol biosynthesis (engineered)";"GDP-mannose biosynthesis";"Chitin biosynthesis" maker-scaffold171size496979-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold254size288410-augustus-gene-1.12-mRNA-1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-5689877 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Josephin domain DUBs" maker-scaffold59size767954-augustus-gene-6.7-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold11size1424826-augustus-gene-4.4-mRNA-1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" maker-scaffold37size976698-augustus-gene-6.7-mRNA-1 1 Reactome: R-HSA-191859 "snRNP Assembly" maker-scaffold990size33689-augustus-gene-0.1-mRNA-1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" maker-scaffold76size663279-augustus-gene-1.3-mRNA-1 7 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" maker-scaffold1364size20936-augustus-gene-0.0-mRNA-1 5 KEGG: 00970+6.1.1.4;Reactome: R-HSA-5419276;Reactome: R-HSA-379726;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation termination";"Mitochondrial tRNA aminoacylation";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold1size2756217-augustus-gene-2.2-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" maker-scaffold36size1013817-augustus-gene-9.9-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold6size1916839-augustus-gene-15.2-mRNA-1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" maker-scaffold42size1661181-augustus-gene-13.3-mRNA-1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" maker-scaffold204size341257-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold638size73239-augustus-gene-0.0-mRNA-1 4 KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-2162123;Reactome: R-HSA-6798695 "Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Neutrophil degranulation" maker-scaffold133size449948-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold147size424191-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" maker-scaffold439size137304-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" maker-scaffold5size1727520-augustus-gene-16.18-mRNA-1 11 MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-5123;Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-7560;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-7524 "Mevalonate pathway I";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Methylerythritol phosphate pathway II";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)" maker-scaffold14750size14092-augustus-gene-0.0-mRNA-1 24 Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-4420097;Reactome: R-HSA-9634600;Reactome: R-HSA-422356;Reactome: R-HSA-442720;KEGG: 04150+2.7.11.11;Reactome: R-HSA-111931;Reactome: R-HSA-9010642;Reactome: R-HSA-5610783;Reactome: R-HSA-180024;Reactome: R-HSA-8963896;Reactome: R-HSA-5610780;Reactome: R-HSA-8853659;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-392517;Reactome: R-HSA-5621575;Reactome: R-HSA-163560 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling";"VEGFA-VEGFR2 Pathway";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Regulation of insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"mTOR signaling pathway";"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"Degradation of GLI2 by the proteasome";"DARPP-32 events";"HDL assembly";"Degradation of GLI1 by the proteasome";"RET signaling";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Rap1 signalling";"CD209 (DC-SIGN) signaling";"Triglyceride catabolism" maker-scaffold31size1053862-augustus-gene-5.1-mRNA-1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" augustus-scaffold1330size21451-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold145size712617-augustus-gene-6.9-mRNA-1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" maker-scaffold288size250223-augustus-gene-1.3-mRNA-1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" maker-scaffold1size2756217-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" maker-scaffold21094size7475-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold264size273138-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold210size338753-augustus-gene-2.18-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold548size90716-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-975957;MetaCyc: PWY-7511 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Protein ubiquitination" maker-scaffold430size141210-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" maker-scaffold721size53923-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" maker-scaffold228size313446-augustus-gene-2.5-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold829size44253-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" maker-scaffold113size504212-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" augustus-scaffold2586size8983-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold931size37200-augustus-gene-0.1-mRNA-1 2 MetaCyc: PWY-6164;KEGG: 00400+2.5.1.54 "3-dehydroquinate biosynthesis I";"Phenylalanine, tyrosine and tryptophan biosynthesis" maker-scaffold306size232476-augustus-gene-0.0-mRNA-1 5 KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-389661 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation" maker-scaffold1size2756217-augustus-gene-11.1-mRNA-1 9 Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" maker-scaffold9size1444705-augustus-gene-5.5-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold2size2657229-augustus-gene-24.5-mRNA-1 1 Reactome: R-HSA-1632852 "Macroautophagy" maker-scaffold129size456722-augustus-gene-3.7-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression" maker-scaffold13size1375079-augustus-gene-4.22-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold650size64829-augustus-gene-0.1-mRNA-1 10 MetaCyc: PWY-7790;MetaCyc: PWY-5154;Reactome: R-HSA-500753;MetaCyc: PWY-7400;KEGG: 00240+2.1.3.2;KEGG: 00250+2.1.3.2;KEGG: 00250+6.3.5.5;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5686;MetaCyc: PWY-7791 "UMP biosynthesis II";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III" maker-scaffold348size205418-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold161size412613-augustus-gene-0.2-mRNA-1 56 Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-350562 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)" maker-scaffold97size566834-augustus-gene-3.5-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold4494size3461-augustus-gene-0.1-mRNA-1 5 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" maker-scaffold248size292329-augustus-gene-1.8-mRNA-1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" maker-scaffold16size1255579-augustus-gene-11.21-mRNA-1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" maker-scaffold2size2657229-augustus-gene-16.1-mRNA-1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" maker-scaffold2size2657229-augustus-gene-13.2-mRNA-1 1 Reactome: R-HSA-5357905 "Regulation of TNFR1 signaling" maker-scaffold32size1041436-augustus-gene-9.2-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold49size896674-augustus-gene-4.0-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold120size483217-augustus-gene-0.3-mRNA-1 4 KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" maker-scaffold76size663279-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" maker-scaffold164size409319-augustus-gene-0.5-mRNA-1 1 Reactome: R-HSA-71384 "Ethanol oxidation" maker-scaffold254size288410-augustus-gene-1.8-mRNA-1 7 KEGG: 00270+6.3.2.2;Reactome: R-HSA-5578999;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-174403;MetaCyc: PWY-6840 "Cysteine and methionine metabolism";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Homoglutathione biosynthesis" maker-scaffold14size1670589-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold24size1136029-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" maker-scaffold2959size7617-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" maker-scaffold4965size7915-augustus-gene-0.1-mRNA-1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" maker-scaffold2375size9895-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" maker-scaffold34size991984-augustus-gene-3.15-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold2size2657229-augustus-gene-13.4-mRNA-1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" maker-scaffold49size896674-augustus-gene-5.6-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold8size1945031-augustus-gene-16.3-mRNA-1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway" maker-scaffold293size245513-augustus-gene-1.1-mRNA-1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" maker-scaffold254size288410-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" maker-scaffold163size408523-augustus-gene-3.7-mRNA-1 1 Reactome: R-HSA-74217 "Purine salvage" maker-scaffold9size1444705-augustus-gene-5.4-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold34size991984-augustus-gene-7.0-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold3706size9865-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" maker-scaffold96size574823-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" maker-scaffold3109size6859-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" maker-scaffold3size2782310-augustus-gene-16.0-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold112size514619-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold1082size29473-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold40size889475-augustus-gene-6.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold33size1007119-augustus-gene-8.4-mRNA-1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" maker-scaffold23size1161859-augustus-gene-7.0-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold270size268122-augustus-gene-1.4-mRNA-1 33 Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-69273;Reactome: R-HSA-76042;Reactome: R-HSA-69231;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-69202;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"Formation of Incision Complex in GG-NER";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" maker-scaffold1636size20727-augustus-gene-0.1-mRNA-1 6 Reactome: R-HSA-9640463;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Wax biosynthesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold24size1136029-augustus-gene-9.3-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold631size92892-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold521size100404-augustus-gene-0.0-mRNA-1 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" augustus-scaffold2193size10980-processed-gene-0.0-mRNA-1 8 Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-180024 "Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"PKA activation";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events" maker-scaffold1049size30937-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-2187335;Reactome: R-HSA-427975;Reactome: R-HSA-2453902 "The retinoid cycle in cones (daylight vision)";"Proton/oligopeptide cotransporters";"The canonical retinoid cycle in rods (twilight vision)" maker-scaffold190size360960-augustus-gene-2.3-mRNA-1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" maker-scaffold52size909272-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" maker-scaffold9size1444705-augustus-gene-12.1-mRNA-1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" maker-scaffold24size1136029-augustus-gene-8.2-mRNA-1 4 MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4 "Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism" maker-scaffold6362size2710-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold45size832949-augustus-gene-4.32-mRNA-1 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" maker-scaffold24size1136029-augustus-gene-3.14-mRNA-1 30 Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5610785;Reactome: R-HSA-2565942;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546 "Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"Circadian Clock";"Iron uptake and transport";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Prolactin receptor signaling" maker-scaffold8size1945031-augustus-gene-7.10-mRNA-1 8 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" maker-scaffold169size953240-augustus-gene-8.5-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" maker-scaffold200size345481-augustus-gene-2.4-mRNA-1 8 Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange" maker-scaffold22size1201825-augustus-gene-11.5-mRNA-1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" maker-scaffold3371size9447-augustus-gene-0.0-mRNA-1 6 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-71262;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Carnitine synthesis";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" maker-scaffold41size887692-augustus-gene-6.0-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold2size2657229-augustus-gene-18.8-mRNA-1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" maker-scaffold138size440403-augustus-gene-3.15-mRNA-1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" maker-scaffold108size522426-augustus-gene-2.0-mRNA-1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold1size2756217-augustus-gene-4.14-mRNA-1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-936837;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Ion transport by P-type ATPases";"COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold8size1945031-augustus-gene-4.8-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold1size2756217-augustus-gene-20.2-mRNA-1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" maker-scaffold31size1053862-augustus-gene-9.1-mRNA-1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580 "Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence" maker-scaffold2064size31533-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold1639size22994-augustus-gene-0.2-mRNA-1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" maker-scaffold367size190875-augustus-gene-0.16-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold47size1319914-augustus-gene-3.4-mRNA-1 1 Reactome: R-HSA-977347 "Serine biosynthesis" maker-scaffold24size1136029-augustus-gene-7.3-mRNA-1 8 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-3214847;Reactome: R-HSA-1855204 "Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"HATs acetylate histones";"Synthesis of IP3 and IP4 in the cytosol" maker-scaffold80size1421260-augustus-gene-2.2-mRNA-1 13 KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662 "Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism" maker-scaffold9size1444705-augustus-gene-2.2-mRNA-1 10 Reactome: R-HSA-83936;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167161 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation" maker-scaffold96size574823-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300 "Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors" maker-scaffold124size587478-augustus-gene-4.2-mRNA-1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" maker-scaffold16size1255579-augustus-gene-4.13-mRNA-1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" maker-scaffold366size192002-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold2size2657229-augustus-gene-18.2-mRNA-1 9 KEGG: 00982+2.5.1.18;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-4061 "Drug metabolism - cytochrome P450";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Drug metabolism - other enzymes";"Glutathione metabolism";"Glutathione-mediated detoxification I" maker-scaffold9size1444705-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" maker-scaffold77size662763-augustus-gene-5.25-mRNA-1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" maker-scaffold24size1136029-augustus-gene-3.5-mRNA-1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" maker-scaffold5size1727520-augustus-gene-1.0-mRNA-1 19 Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275 "Retinoid metabolism and transport";"Scavenging by Class H Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"LDL remodeling";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"VLDL assembly";"Post-translational protein phosphorylation" maker-scaffold2524size9268-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold75size670735-augustus-gene-0.1-mRNA-1 16 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;MetaCyc: PWY-7546;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-5358493;MetaCyc: PWY-6482;Reactome: R-HSA-2408557 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Diphthamide biosynthesis II (eukaryotes)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Selenocysteine synthesis" maker-scaffold460size128090-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-70921 "Histidine catabolism" maker-scaffold92size586643-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold48size811354-augustus-gene-4.14-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold5size1727520-augustus-gene-9.4-mRNA-1 6 MetaCyc: PWY-7863;MetaCyc: PWY-5523;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-3214847;Reactome: R-HSA-196843 "Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"HATs acetylate histones";"Vitamin B2 (riboflavin) metabolism" maker-scaffold446size134571-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" maker-scaffold14size1670589-augustus-gene-7.4-mRNA-1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473 "HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint" maker-scaffold14size1670589-augustus-gene-15.22-mRNA-1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" maker-scaffold145size712617-augustus-gene-6.12-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold12size1412574-augustus-gene-13.12-mRNA-1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" maker-scaffold37size976698-augustus-gene-8.4-mRNA-1 53 Reactome: R-HSA-203927;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-76066;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-204626;Reactome: R-HSA-427413;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-73780;Reactome: R-HSA-168325;Reactome: R-HSA-167290;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-72086 "MicroRNA (miRNA) biogenesis";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Hypusine synthesis from eIF5A-lysine";"NoRC negatively regulates rRNA expression";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Chain Elongation";"Viral Messenger RNA Synthesis";"Pausing and recovery of HIV elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping" maker-scaffold18size2240851-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" maker-scaffold5size1727520-augustus-gene-16.16-mRNA-1 26 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-437239 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1" maker-scaffold1size2756217-augustus-gene-24.1-mRNA-1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" maker-scaffold16size1255579-augustus-gene-2.1-mRNA-1 13 MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7410;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5122;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-6383 "Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" maker-scaffold4120size3964-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1632852 "Macroautophagy" maker-scaffold54size1273868-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" maker-scaffold8size1945031-augustus-gene-7.9-mRNA-1 4 Reactome: R-HSA-1971475;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00534+2.4.2.26 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" maker-scaffold2130size11509-augustus-gene-0.0-mRNA-1 6 MetaCyc: PWY-5981;MetaCyc: PWY-5667;Reactome: R-HSA-6785631;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"ERBB2 Regulates Cell Motility";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA" maker-scaffold135size449244-augustus-gene-3.3-mRNA-1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold8size1945031-augustus-gene-10.0-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold21size1197050-augustus-gene-4.15-mRNA-1 23 Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-428930;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-392170;Reactome: R-HSA-420092 "G alpha (q) signalling events";"Ca2+ pathway";"G alpha (s) signalling events";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors" maker-scaffold255size285696-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold35size976498-augustus-gene-6.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold634size71122-augustus-gene-0.3-mRNA-1 10 Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942 "G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)" maker-scaffold43size857109-augustus-gene-4.20-mRNA-1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-5663220;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5673000 "Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation" maker-scaffold2size2657229-augustus-gene-18.5-mRNA-1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold664size65968-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" maker-scaffold77size662763-augustus-gene-2.0-mRNA-1 12 KEGG: 00720+4.1.3.25;MetaCyc: PWY-7118;KEGG: 00630+3.1.2.30+2.3.3.9;MetaCyc: PWY-5744;MetaCyc: PWY-7854;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7295;MetaCyc: PWY-6728;MetaCyc: PWY-5749;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-6969 "Carbon fixation pathways in prokaryotes";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Glyoxylate assimilation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"C5-Branched dibasic acid metabolism";"L-arabinose degradation IV";"Methylaspartate cycle";"Itaconate degradation";"Pyruvate metabolism";"D-xylose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" maker-scaffold103size553987-augustus-gene-3.0-mRNA-1 5 Reactome: R-HSA-446210;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism" maker-scaffold266size269306-augustus-gene-1.3-mRNA-1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" maker-scaffold811size45847-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold1size2756217-augustus-gene-5.5-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold1size2756217-augustus-gene-11.6-mRNA-1 9 Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69205;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166 "Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate" maker-scaffold363size197171-augustus-gene-1.8-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold1062size30211-augustus-gene-0.2-mRNA-1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" maker-scaffold24size1136029-augustus-gene-10.2-mRNA-1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Amino acids regulate mTORC1";"Insulin receptor recycling";"Neutrophil degranulation";"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" maker-scaffold284size253718-augustus-gene-1.13-mRNA-1 3 Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway" maker-scaffold441size150191-augustus-gene-0.10-mRNA-1 1 Reactome: R-HSA-1632852 "Macroautophagy" maker-scaffold5725size9787-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" maker-scaffold8size1945031-augustus-gene-4.15-mRNA-1 3 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31;Reactome: R-HSA-8949664 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Processing of SMDT1" maker-scaffold222size322023-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold116size557669-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" maker-scaffold44size860316-augustus-gene-5.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold202size342994-augustus-gene-1.0-mRNA-1 13 KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"CS/DS degradation";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism" maker-scaffold48size811354-augustus-gene-1.2-mRNA-1 9 Reactome: R-HSA-5658442;Reactome: R-HSA-6781823;Reactome: R-HSA-176974;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-2559584;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Regulation of RAS by GAPs";"Formation of TC-NER Pre-Incision Complex";"Unwinding of DNA";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Formation of Senescence-Associated Heterochromatin Foci (SAHF)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" maker-scaffold24size1136029-augustus-gene-8.0-mRNA-1 1 Reactome: R-HSA-373753 "Nephrin family interactions" maker-scaffold659size62711-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" maker-scaffold96size574823-augustus-gene-3.0-mRNA-1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" maker-scaffold1size2756217-augustus-gene-17.7-mRNA-1 19 KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-7115;MetaCyc: PWY-6969;MetaCyc: PWY-1622;Reactome: R-HSA-71403;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728 "Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Methane metabolism";"Cysteine and methionine metabolism";"Methylaspartate cycle" maker-scaffold1size2756217-augustus-gene-15.0-mRNA-1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" maker-scaffold42size1661181-augustus-gene-2.19-mRNA-1 8 Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148 "Activation of AMPK downstream of NMDARs";"Lipophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold11size1424826-augustus-gene-3.5-mRNA-1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" augustus-scaffold1121size27994-processed-gene-0.0-mRNA-1 8 MetaCyc: PWY-7892;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185;Reactome: R-HSA-6787450;Reactome: R-HSA-499943;MetaCyc: PWY-7887;MetaCyc: PWY-7177;MetaCyc: PWY-7176 "Trna-uridine 2-thiolation and selenation (bacteria)";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"tRNA modification in the mitochondrion";"Interconversion of nucleotide di- and triphosphates";"Protein SAMPylation and SAMP-mediated thiolation";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis" maker-scaffold214size663695-augustus-gene-2.1-mRNA-1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" maker-scaffold238size302402-augustus-gene-1.2-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold1239size23493-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold12size1412574-augustus-gene-9.1-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold218size326752-augustus-gene-2.8-mRNA-1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" maker-scaffold177size387897-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold129size456722-augustus-gene-1.1-mRNA-1 11 Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-110314 "Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex" maker-scaffold947size36242-augustus-gene-0.1-mRNA-1 10 MetaCyc: PWY-5723;Reactome: R-HSA-8950505;Reactome: R-HSA-6791055;KEGG: 00520+2.4.1.16;Reactome: R-HSA-71336;MetaCyc: PWY-6981;Reactome: R-HSA-163754;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-6791462 "Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Chitin biosynthesis";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P" maker-scaffold26size1667613-augustus-gene-15.4-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold8368size14419-augustus-gene-0.1-mRNA-1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" maker-scaffold48size811354-augustus-gene-7.3-mRNA-1 5 Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system" maker-scaffold47size1319914-augustus-gene-3.0-mRNA-1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" maker-scaffold11size1424826-augustus-gene-3.6-mRNA-1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold54size1273868-augustus-gene-11.6-mRNA-1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" maker-scaffold350size203295-augustus-gene-1.3-mRNA-1 4 Reactome: R-HSA-70921;MetaCyc: PWY-5030;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5028 "Histidine catabolism";"L-histidine degradation III";"Histidine metabolism";"L-histidine degradation II" maker-scaffold20size1234842-augustus-gene-4.15-mRNA-1 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" maker-scaffold314size226823-augustus-gene-1.0-mRNA-1 2 KEGG: 00330+3.5.3.12;MetaCyc: PWY-43 "Arginine and proline metabolism";"Putrescine biosynthesis II" maker-scaffold254size288410-augustus-gene-1.14-mRNA-1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" maker-scaffold154size420078-augustus-gene-3.12-mRNA-1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" maker-scaffold200size345481-augustus-gene-2.5-mRNA-1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" maker-scaffold89size602897-augustus-gene-5.24-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold34size991984-augustus-gene-7.3-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold1size2756217-augustus-gene-13.0-mRNA-1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" maker-scaffold367size190875-augustus-gene-0.12-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold85size629767-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" maker-scaffold18size2240851-augustus-gene-18.0-mRNA-1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" maker-scaffold544size92723-augustus-gene-0.4-mRNA-1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" maker-scaffold169size953240-augustus-gene-6.1-mRNA-1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-1799339;Reactome: R-HSA-446203;Reactome: R-HSA-879415 "Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling" maker-scaffold25size1130848-augustus-gene-1.6-mRNA-1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" maker-scaffold77size662763-augustus-gene-5.23-mRNA-1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" maker-scaffold16size1255579-augustus-gene-8.2-mRNA-1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" maker-scaffold8size1945031-augustus-gene-13.0-mRNA-1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" maker-scaffold227size314013-augustus-gene-2.13-mRNA-1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" maker-scaffold31size1053862-augustus-gene-3.2-mRNA-1 7 Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516 "Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin" maker-scaffold1489size18786-augustus-gene-0.2-mRNA-1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109 "O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis" maker-scaffold242size299879-augustus-gene-2.15-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" augustus-scaffold2737size8332-processed-gene-0.0-mRNA-1 18 KEGG: 00620+1.8.1.4;KEGG: 00380+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-6783984;Reactome: R-HSA-70268;KEGG: 00640+1.8.1.4;KEGG: 00280+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00020+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00310+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5084 "Pyruvate metabolism";"Tryptophan metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine degradation";"Pyruvate metabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Citrate cycle (TCA cycle)";"Glycine, serine and threonine metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Lysine degradation";"Lysine catabolism";"Glycolysis / Gluconeogenesis";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" augustus-scaffold612size75004-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-400253 "Circadian Clock" maker-scaffold12size1412574-augustus-gene-6.5-mRNA-1 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" maker-scaffold89size602897-augustus-gene-1.7-mRNA-1 1 Reactome: R-HSA-8876725 "Protein methylation" maker-scaffold443size134888-augustus-gene-0.5-mRNA-1 10 KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"RSK activation";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis" maker-scaffold213size330819-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold138size440403-augustus-gene-3.0-mRNA-1 18 MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7197;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6 "UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine metabolism" maker-scaffold96size574823-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" maker-scaffold121size481755-augustus-gene-0.0-mRNA-1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" maker-scaffold21size1197050-augustus-gene-11.0-mRNA-1 16 Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174184 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" maker-scaffold608size111783-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold629size81683-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" maker-scaffold12773size7491-augustus-gene-0.1-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold1247size23272-augustus-gene-0.1-mRNA-1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" maker-scaffold157size419459-augustus-gene-1.3-mRNA-1 13 MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916 "Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation" maker-scaffold507size105377-augustus-gene-0.2-mRNA-1 6 Reactome: R-HSA-156588;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;Reactome: R-HSA-73621;MetaCyc: PWY-5189 "Glucuronidation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Pyrimidine catabolism";"Tetrapyrrole biosynthesis II (from glycine)" maker-scaffold337size211899-augustus-gene-0.2-mRNA-1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" maker-scaffold1669size16154-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold1size2756217-augustus-gene-4.1-mRNA-1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" maker-scaffold546size91324-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold1size2756217-augustus-gene-9.1-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold2size2657229-augustus-gene-6.7-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold88size603654-augustus-gene-5.0-mRNA-1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" maker-scaffold13size1375079-augustus-gene-12.7-mRNA-1 4 MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072 "Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Alanine racemization" maker-scaffold344size208274-augustus-gene-0.5-mRNA-1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold18size2240851-augustus-gene-11.2-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold37size976698-augustus-gene-6.0-mRNA-1 11 Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5694530;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-5663220;Reactome: R-HSA-204005 "MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Cargo concentration in the ER";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"RHO GTPases Activate Formins";"COPII-mediated vesicle transport" maker-scaffold163size408523-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold320size221394-augustus-gene-1.0-mRNA-1 13 KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7184;Reactome: R-HSA-74259;KEGG: 00500+3.6.1.9 "Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pantothenate and CoA biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine catabolism";"Starch and sucrose metabolism" maker-scaffold13size1375079-augustus-gene-4.20-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold423size145723-augustus-gene-0.6-mRNA-1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" maker-scaffold161size412613-augustus-gene-2.2-mRNA-1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" maker-scaffold20size1234842-augustus-gene-7.0-mRNA-1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state" maker-scaffold16size1255579-augustus-gene-11.2-mRNA-1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" maker-scaffold770size49534-augustus-gene-0.1-mRNA-1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination" maker-scaffold14size1670589-augustus-gene-7.6-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" augustus-scaffold4179size3850-processed-gene-0.1-mRNA-1 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" maker-scaffold608size111783-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold20size1234842-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" maker-scaffold53size789746-augustus-gene-7.2-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold464size126411-augustus-gene-0.6-mRNA-1 33 Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"snRNP Assembly";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" maker-scaffold3size2782310-augustus-gene-11.4-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold110size515606-augustus-gene-2.4-mRNA-1 11 Reactome: R-HSA-6798163;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-936837;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776 "Choline catabolism";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Ion transport by P-type ATPases";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape" maker-scaffold96size574823-augustus-gene-0.2-mRNA-1 56 Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1" maker-scaffold14size1670589-augustus-gene-14.1-mRNA-1 4 KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis" maker-scaffold57size773389-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold66size1200099-augustus-gene-1.0-mRNA-1 9 KEGG: 00510+2.4.1.141;KEGG: 00513+2.4.1.141;KEGG: 00550+2.4.1.227;Reactome: R-HSA-5633231;MetaCyc: PWY-6471;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)" maker-scaffold2658size8659-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" maker-scaffold50size801739-augustus-gene-5.3-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold13size1375079-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" maker-scaffold424size145378-augustus-gene-0.5-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold4size1754260-augustus-gene-14.2-mRNA-1 6 Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPII-mediated vesicle transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold42size1661181-augustus-gene-2.18-mRNA-1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" maker-scaffold270size268122-augustus-gene-1.9-mRNA-1 9 Reactome: R-HSA-110331;Reactome: R-HSA-9608290;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-9608287 "Cleavage of the damaged purine";"Defective MUTYH substrate processing";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Defective MUTYH substrate binding" maker-scaffold17size1249603-augustus-gene-11.22-mRNA-1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" maker-scaffold78size655360-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" maker-scaffold291size245474-augustus-gene-1.0-mRNA-1 13 MetaCyc: PWY-7384;MetaCyc: PWY-561;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;KEGG: 00720+4.2.1.2 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes" maker-scaffold335size212668-augustus-gene-1.12-mRNA-1 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" maker-scaffold149size424757-augustus-gene-1.6-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold5size1727520-augustus-gene-13.6-mRNA-1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" augustus-scaffold704size55912-processed-gene-0.1-mRNA-1 25 Reactome: R-HSA-71336;Reactome: R-HSA-77289;MetaCyc: PWY-7383;MetaCyc: PWY-8004;Reactome: R-HSA-203927;Reactome: R-HSA-70171;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1;Reactome: R-HSA-6799198;MetaCyc: PWY-7003;Reactome: R-HSA-611105;KEGG: 00620+2.7.1.40;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5484;Reactome: R-HSA-389661;MetaCyc: PWY-1042 "Pentose phosphate pathway";"Mitochondrial Fatty Acid Beta-Oxidation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway I";"MicroRNA (miRNA) biogenesis";"Glycolysis";"Rubisco shunt";"Carbon fixation in photosynthetic organisms";"Complex I biogenesis";"Glycerol degradation to butanol";"Respiratory electron transport";"Pyruvate metabolism";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Glyoxylate metabolism and glycine degradation";"Glycolysis IV (plant cytosol)" maker-scaffold79size709353-augustus-gene-1.3-mRNA-1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" maker-scaffold22size1201825-augustus-gene-5.4-mRNA-1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" maker-scaffold587size81631-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-189451 "Heme biosynthesis" augustus-scaffold767size49991-processed-gene-0.0-mRNA-1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" maker-scaffold37size976698-augustus-gene-3.4-mRNA-1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs" maker-scaffold49size896674-augustus-gene-8.1-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold5size1727520-augustus-gene-16.6-mRNA-1 8 Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111463 "Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs" maker-scaffold4size1754260-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" maker-scaffold22size1201825-augustus-gene-8.2-mRNA-1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" maker-scaffold161size412613-augustus-gene-3.6-mRNA-1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" maker-scaffold2size2657229-augustus-gene-22.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold429size142089-augustus-gene-0.9-mRNA-1 6 Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017 "Neutrophil degranulation";"Tryptophan metabolism";"Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" maker-scaffold120size483217-augustus-gene-0.4-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold21size1197050-augustus-gene-3.4-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold5size1727520-augustus-gene-4.5-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" augustus-scaffold1890size13733-processed-gene-0.1-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold34size991984-augustus-gene-3.20-mRNA-1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" maker-scaffold5615size2934-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" maker-scaffold155size419694-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold12size1412574-augustus-gene-6.3-mRNA-1 3 Reactome: R-HSA-1660662;MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12 "Glycosphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism" maker-scaffold147size424191-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold2028size19297-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold105size529344-augustus-gene-4.8-mRNA-1 10 KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05163+2.7.1.153 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"Human cytomegalovirus infection" maker-scaffold169size953240-augustus-gene-3.3-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold241size304314-augustus-gene-2.0-mRNA-1 31 MetaCyc: PWY-5366;MetaCyc: PWY-6113;MetaCyc: PWY-6519;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5973;MetaCyc: PWY-5147;Reactome: R-HSA-9029558;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-7388;Reactome: R-HSA-2426168;MetaCyc: PWY-6799;MetaCyc: PWY-7858;MetaCyc: PWY-5971;MetaCyc: PWY-8049;MetaCyc: PWY-6282;Reactome: R-HSA-163765;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-5989;MetaCyc: PWY-5994;MetaCyc: PWY-7663;Reactome: R-HSA-199220;Reactome: R-HSA-75105;MetaCyc: PWY-8047;MetaCyc: PWY-7723;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-4381;MetaCyc: PWY-8012;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321 "Palmitoleate biosynthesis II (plants and bacteria)";"Superpathway of mycolate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Oleate biosynthesis I (plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (plant mitochondria)";"(5Z)-dodecenoate biosynthesis II";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Pederin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"ChREBP activates metabolic gene expression";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Bryostatin biosynthesis";"Bacterial bioluminescence";"Biotin metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mupirocin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"" maker-scaffold42size1661181-augustus-gene-3.3-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" augustus-scaffold3337size5893-processed-gene-0.0-mRNA-1 13 MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" maker-scaffold1443size19522-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold7size1668642-augustus-gene-15.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold23size1161859-augustus-gene-2.4-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold2size2657229-augustus-gene-14.0-mRNA-1 10 MetaCyc: PWY-922;MetaCyc: PWY-7571;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00900+2.3.3.10;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00650+2.3.3.10 "Mevalonate pathway I";"Ferrichrome A biosynthesis";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Butanoate metabolism" maker-scaffold21size1197050-augustus-gene-4.11-mRNA-1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" maker-scaffold251size291382-augustus-gene-1.7-mRNA-1 7 MetaCyc: PWY-7118;MetaCyc: PWY-7854;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7295;MetaCyc: PWY-7294;KEGG: 00620+2.3.3.9;MetaCyc: PWY-6969 "Chitin degradation to ethanol";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Glyoxylate and dicarboxylate metabolism";"L-arabinose degradation IV";"D-xylose degradation IV";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" maker-scaffold17size1249603-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" maker-scaffold45size832949-augustus-gene-4.2-mRNA-1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" maker-scaffold7size1668642-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold53size789746-augustus-gene-0.2-mRNA-1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" maker-scaffold34size991984-augustus-gene-6.4-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold260size277064-augustus-gene-1.6-mRNA-1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" maker-scaffold16259size7398-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" maker-scaffold484size118506-augustus-gene-0.11-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold106size612477-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold217size397381-augustus-gene-2.1-mRNA-1 3 Reactome: R-HSA-193368;Reactome: R-HSA-159418;Reactome: R-HSA-5678520 "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Recycling of bile acids and salts";"Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2" maker-scaffold632size67919-augustus-gene-0.1-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold987size33957-augustus-gene-0.0-mRNA-1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" maker-scaffold2550size9167-augustus-gene-0.0-mRNA-1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084 "Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" maker-scaffold67size700687-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" maker-scaffold127size531218-augustus-gene-2.0-mRNA-1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" maker-scaffold14size1670589-augustus-gene-8.4-mRNA-1 8 KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11 "Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism" maker-scaffold484size118506-augustus-gene-0.7-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold157size419459-augustus-gene-3.15-mRNA-1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" maker-scaffold2108size11631-augustus-gene-0.1-mRNA-1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold2389size9805-augustus-gene-0.0-mRNA-1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" maker-scaffold560size87469-augustus-gene-0.4-mRNA-1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" maker-scaffold53size789746-augustus-gene-1.3-mRNA-1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" maker-scaffold2size2657229-augustus-gene-24.0-mRNA-1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" maker-scaffold4627size7632-augustus-gene-0.0-mRNA-1 14 KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-2201;KEGG: 00680+2.1.2.1;MetaCyc: PWY-5497;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;MetaCyc: PWY-3841;MetaCyc: PWY-181;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1 "One carbon pool by folate";"Glycine betaine degradation I";"Folate transformations I";"Methane metabolism";"Purine nucleobases degradation II (anaerobic)";"Glycine, serine and threonine metabolism";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Folate transformations II (plants)";"Photorespiration ";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism" maker-scaffold2284size14541-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" maker-scaffold107size522501-augustus-gene-3.0-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold2size2657229-augustus-gene-25.24-mRNA-1 6 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5789 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" maker-scaffold400size160987-augustus-gene-0.2-mRNA-1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" augustus-scaffold500size107027-processed-gene-0.1-mRNA-1 15 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-936837;Reactome: R-HSA-6782315;Reactome: R-HSA-9640463;KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2408522 "Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Ion transport by P-type ATPases";"tRNA modification in the nucleus and cytosol";"Wax biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Selenoamino acid metabolism" maker-scaffold31size1053862-augustus-gene-3.3-mRNA-1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" maker-scaffold36size1013817-augustus-gene-8.5-mRNA-1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" maker-scaffold12size1412574-augustus-gene-2.11-mRNA-1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" maker-scaffold223size319359-augustus-gene-2.5-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression" maker-scaffold1098size28945-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold211size331595-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling" maker-scaffold248size292329-augustus-gene-1.11-mRNA-1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" maker-scaffold17size1249603-augustus-gene-11.5-mRNA-1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" maker-scaffold9size1444705-augustus-gene-6.2-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold101size554424-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold148size437419-augustus-gene-3.6-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold21size1197050-augustus-gene-2.4-mRNA-1 1 Reactome: R-HSA-191859 "snRNP Assembly" maker-scaffold260size277064-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" maker-scaffold128size459976-augustus-gene-0.2-mRNA-1 6 MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;MetaCyc: PWY-622;Reactome: R-HSA-189085 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Digestion of dietary carbohydrate" maker-scaffold9967size14913-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold76size663279-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-390651 "Dopamine receptors" maker-scaffold34size991984-augustus-gene-6.3-mRNA-1 7 Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-6785470 "rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Receptor Mediated Mitophagy";"tRNA processing in the mitochondrion" maker-scaffold212size330836-augustus-gene-2.3-mRNA-1 56 Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603 "APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases" maker-scaffold268size268435-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold3size2782310-augustus-gene-12.0-mRNA-1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" maker-scaffold334size326235-augustus-gene-2.1-mRNA-1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" maker-scaffold361size197669-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" maker-scaffold15size1261043-augustus-gene-7.0-mRNA-1 10 MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;MetaCyc: PWY-5340;Reactome: R-HSA-2408550;Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4 "Sulfite oxidation III";"Purine metabolism";"Selenate reduction";"Sulfate activation for sulfonation";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Monobactam biosynthesis";"Sulfur metabolism";"Selenocompound metabolism" maker-scaffold59size767954-augustus-gene-3.2-mRNA-1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" maker-scaffold1size2756217-augustus-gene-17.1-mRNA-1 13 Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-1474244;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-186797;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-216083 "Collagen chain trimerization";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Extracellular matrix organization";"NCAM1 interactions";"ECM proteoglycans";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Laminin interactions";"Signaling by PDGF";"Collagen degradation";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions" maker-scaffold383size174942-augustus-gene-0.2-mRNA-1 5 Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006 "Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" maker-scaffold242size299879-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold42size1661181-augustus-gene-13.7-mRNA-1 9 Reactome: R-HSA-1855204;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Inositol phosphate metabolism" maker-scaffold84size638750-augustus-gene-2.1-mRNA-1 9 Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome" maker-scaffold39size909063-augustus-gene-4.0-mRNA-1 3 KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis" maker-scaffold99size561911-augustus-gene-2.0-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold14size1670589-augustus-gene-8.1-mRNA-1 13 KEGG: 00660+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5538;KEGG: 00020+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6969;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690 "C5-Branched dibasic acid metabolism";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Propanoate metabolism";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)" maker-scaffold10size1426409-augustus-gene-13.13-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold28size1079920-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold70size694644-augustus-gene-3.9-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold4size1754260-augustus-gene-14.0-mRNA-1 19 Reactome: R-HSA-5686938;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8856828 "Regulation of TLR by endogenous ligand";"LDL remodeling";"Scavenging by Class A Receptors";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"VLDL assembly";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron assembly";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis" maker-scaffold76size663279-augustus-gene-5.5-mRNA-1 3 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" maker-scaffold2size2657229-augustus-gene-11.2-mRNA-1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" maker-scaffold225size316554-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold59size767954-augustus-gene-2.1-mRNA-1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" maker-scaffold4656size8160-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold801size46879-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" maker-scaffold76size663279-augustus-gene-4.7-mRNA-1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" augustus-scaffold924size37480-processed-gene-0.0-mRNA-1 42 Reactome: R-HSA-1474151;MetaCyc: PWY-7791;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-5686;MetaCyc: PWY-5664;Reactome: R-HSA-2151201;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7980;Reactome: R-HSA-1483213;MetaCyc: PWY-6703;KEGG: 00190+7.1.2.2;KEGG: 00970+6.1.1.16;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6983;Reactome: R-HSA-3299685;KEGG: 00564+4.1.1.65;KEGG: 00770+3.1.4.14;MetaCyc: PWY-6147;Reactome: R-HSA-8862803;MetaCyc: PWY-7559;KEGG: 00790+3.5.4.16;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;Reactome: R-HSA-2672351;MetaCyc: PWY-6854;KEGG: 00460+2.3.2.2;Reactome: R-HSA-9615017;MetaCyc: PWY-5669;KEGG: 00195+7.1.2.2;MetaCyc: PWY-5663;KEGG: 00240+2.4.2.10;MetaCyc: PWY-6012;MetaCyc: PWY-7442;MetaCyc: PWY-5826;MetaCyc: PWY-7790;MetaCyc: PWY-6842;Reactome: R-HSA-8950505;Reactome: R-HSA-8949664;MetaCyc: PWY-8001;MetaCyc: PWY-7852;Reactome: R-HSA-500753 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"UMP biosynthesis III";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"UMP biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Transcriptional activation of mitochondrial biogenesis";"Drug metabolism - other enzymes";"ATP biosynthesis";"Synthesis of PE";"Preq0 biosynthesis";"Oxidative phosphorylation";"Aminoacyl-tRNA biosynthesis";"Taurine and hypotaurine metabolism";"Threo-tetrahydrobiopterin biosynthesis";"Detoxification of Reactive Oxygen Species";"Glycerophospholipid metabolism";"Pantothenate and CoA biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Glutathione degradation (DUG pathway";"Folate biosynthesis";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Stimuli-sensing channels";"Ethylene biosynthesis III (microbes)";"Cyanoamino acid metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Photosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Pyrimidine metabolism";"Acyl carrier protein metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Hypoglycin biosynthesis";"UMP biosynthesis II";"Glutathione-mediated detoxification II";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Processing of SMDT1";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Pyrimidine biosynthesis" maker-scaffold320size221394-augustus-gene-1.1-mRNA-1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" maker-scaffold120size483217-augustus-gene-1.1-mRNA-1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" maker-scaffold3size2782310-augustus-gene-4.20-mRNA-1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" maker-scaffold28size1079920-augustus-gene-9.3-mRNA-1 1 Reactome: R-HSA-912446 "Meiotic recombination" maker-scaffold99size561911-augustus-gene-2.3-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold169size953240-augustus-gene-5.9-mRNA-1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" maker-scaffold76size663279-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" maker-scaffold7size1668642-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold1size2756217-augustus-gene-26.8-mRNA-1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" maker-scaffold266size269306-augustus-gene-1.15-mRNA-1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" maker-scaffold1size2756217-augustus-gene-20.3-mRNA-1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" maker-scaffold135size449244-augustus-gene-3.4-mRNA-1 6 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-9640463;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Wax biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis" maker-scaffold48size811354-augustus-gene-4.11-mRNA-1 10 MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-6901;Reactome: R-HSA-70263;Reactome: R-HSA-70171 "1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis" maker-scaffold1676size22910-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold310size229811-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold42size1661181-augustus-gene-13.4-mRNA-1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" maker-scaffold18size2240851-augustus-gene-4.12-mRNA-1 2 Reactome: R-HSA-70263;Reactome: R-HSA-70171 "Gluconeogenesis";"Glycolysis" maker-scaffold185size368400-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-8949613 "Cristae formation" maker-scaffold17size1249603-augustus-gene-11.25-mRNA-1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" maker-scaffold47size1319914-augustus-gene-2.3-mRNA-1 9 MetaCyc: PWY-6322;MetaCyc: PWY-7769;MetaCyc: PWY-7510;MetaCyc: PWY-6682;MetaCyc: PWY-8067;KEGG: 00998+4.1.1.82;MetaCyc: PWY-6839;KEGG: 00440+4.1.1.82;MetaCyc: PWY-5757 "Phosphinothricin tripeptide biosynthesis";"Phosalacine biosynthesis";"Rhizocticin A and B biosynthesis";"Dehydrophos biosynthesis";"Methylphosphonate biosynthesis";"Biosynthesis of various secondary metabolites - part 2";"2-aminoethylphosphonate biosynthesis";"Phosphonate and phosphinate metabolism";"Fosfomycin biosynthesis" maker-scaffold6size1916839-augustus-gene-2.1-mRNA-1 18 KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788 "Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC" maker-scaffold13219size7516-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-203615 "eNOS activation" maker-scaffold72size687670-augustus-gene-3.6-mRNA-1 1 Reactome: R-HSA-71288 "Creatine metabolism" maker-scaffold161size412613-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" maker-scaffold12475size7551-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" maker-scaffold6063size9020-augustus-gene-0.1-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold335size212668-augustus-gene-1.14-mRNA-1 4 Reactome: R-HSA-427589;Reactome: R-HSA-5687583;Reactome: R-HSA-5683826;Reactome: R-HSA-5619045 "Type II Na+/Pi cotransporters";"Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)";"Surfactant metabolism";"Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM)" maker-scaffold966size35222-augustus-gene-0.1-mRNA-1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985 "N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose" maker-scaffold4926size20599-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" maker-scaffold21size1197050-augustus-gene-8.4-mRNA-1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-202433;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs" maker-scaffold10size1426409-augustus-gene-3.5-mRNA-1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" maker-scaffold363size197171-augustus-gene-1.1-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression" maker-scaffold3size2782310-augustus-gene-14.0-mRNA-1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" maker-scaffold6size1916839-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" maker-scaffold434size139087-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold54size1273868-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold190size360960-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold2size2657229-augustus-gene-19.3-mRNA-1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" maker-scaffold254size288410-augustus-gene-1.19-mRNA-1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5610787;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922 "Class B/2 (Secretin family receptors)";"Hedgehog 'off' state";"Activation of SMO";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium" maker-scaffold89size602897-augustus-gene-5.3-mRNA-1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" maker-scaffold403size154898-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold37size976698-augustus-gene-8.8-mRNA-1 10 Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-9656255;Reactome: R-HSA-5649702;Reactome: R-HSA-110328;Reactome: R-HSA-9657050;Reactome: R-HSA-9656256;Reactome: R-HSA-9639288 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Binding";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Localization";"Defective OGG1 Substrate Processing";"Amino acids regulate mTORC1" maker-scaffold18size2240851-augustus-gene-3.1-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold105size529344-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" maker-scaffold593size79447-augustus-gene-0.2-mRNA-1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" maker-scaffold1size2756217-augustus-gene-5.8-mRNA-1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" maker-scaffold29size1057726-augustus-gene-6.2-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold246size295413-augustus-gene-2.7-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold4size1754260-augustus-gene-11.5-mRNA-1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" maker-scaffold70size694644-augustus-gene-3.13-mRNA-1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" maker-scaffold1121size27994-augustus-gene-0.2-mRNA-1 15 MetaCyc: PWY-7254;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7221;MetaCyc: PWY-6728;MetaCyc: PWY-6549;Reactome: R-HSA-71403;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;KEGG: 00983+6.3.5.2 "TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Methylaspartate cycle";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Drug metabolism - other enzymes" maker-scaffold362size197294-augustus-gene-0.1-mRNA-1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" maker-scaffold124size587478-augustus-gene-3.1-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold13size1375079-augustus-gene-9.2-mRNA-1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" maker-scaffold110size515606-augustus-gene-4.8-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold980size34325-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" maker-scaffold1010size35290-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" maker-scaffold1963size12995-augustus-gene-0.2-mRNA-1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" maker-scaffold37size976698-augustus-gene-6.2-mRNA-1 10 MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;MetaCyc: PWY-3841;Reactome: R-HSA-499943;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7199;Reactome: R-HSA-69205;MetaCyc: PWY-7210;MetaCyc: PWY-7184 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Folate transformations II (plants)";"Interconversion of nucleotide di- and triphosphates";"One carbon pool by folate";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" maker-scaffold607size76892-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold42size1661181-augustus-gene-15.5-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold3size2782310-augustus-gene-15.5-mRNA-1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" maker-scaffold227size314013-augustus-gene-1.7-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold1045size31166-augustus-gene-0.3-mRNA-1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" maker-scaffold10size1426409-augustus-gene-5.6-mRNA-1 16 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold192size359585-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold31size1053862-augustus-gene-2.5-mRNA-1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" maker-scaffold11size1424826-augustus-gene-6.2-mRNA-1 13 Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-8866427;Reactome: R-HSA-416993;Reactome: R-HSA-437239 "Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"VLDLR internalisation and degradation";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1" maker-scaffold12756size7454-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" maker-scaffold397size365563-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold70size694644-augustus-gene-3.15-mRNA-1 9 Reactome: R-HSA-162699;MetaCyc: PWY-7922;MetaCyc: PWY-7661;Reactome: R-HSA-4717374;KEGG: 00510+2.4.1.83;Reactome: R-HSA-4719360;MetaCyc: PWY-7979;Reactome: R-HSA-4719377;MetaCyc: PWY-7921 "Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"N-Glycan biosynthesis";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation I (yeast)" maker-scaffold246size295413-augustus-gene-2.8-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold70size694644-augustus-gene-4.2-mRNA-1 3 KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle" maker-scaffold157size419459-augustus-gene-3.0-mRNA-1 27 Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3232142 "Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins" maker-scaffold16size1255579-augustus-gene-6.6-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold78size655360-augustus-gene-4.1-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold155size419694-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold4size1754260-augustus-gene-6.0-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold23size1161859-augustus-gene-5.5-mRNA-1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" maker-scaffold783size48704-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold99size561911-augustus-gene-2.1-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold251size291382-augustus-gene-1.8-mRNA-1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" maker-scaffold10size1426409-augustus-gene-9.2-mRNA-1 4 Reactome: R-HSA-5223345;Reactome: R-HSA-425366;Reactome: R-HSA-425393;Reactome: R-HSA-1483191 "Miscellaneous transport and binding events";"Transport of bile salts and organic acids, metal ions and amine compounds";"Transport of inorganic cations/anions and amino acids/oligopeptides";"Synthesis of PC" maker-scaffold74size672076-augustus-gene-2.1-mRNA-1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold266size269306-augustus-gene-1.17-mRNA-1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" maker-scaffold89size602897-augustus-gene-5.5-mRNA-1 4 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" maker-scaffold8138size21721-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold2size2657229-augustus-gene-11.5-mRNA-1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold48size811354-augustus-gene-4.5-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold6size1916839-augustus-gene-4.5-mRNA-1 10 MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041 "Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione degradation (DUG pathway";"Glutathione-mediated detoxification I";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle" maker-scaffold59size767954-augustus-gene-2.2-mRNA-1 6 Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938 "Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)" maker-scaffold78size655360-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" maker-scaffold804size46476-augustus-gene-0.1-mRNA-1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" maker-scaffold16size1255579-augustus-gene-4.24-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold171size496979-augustus-gene-3.3-mRNA-1 6 Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" augustus-scaffold1950size13140-processed-gene-0.0-mRNA-1 7 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-204174;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-5362517;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Regulation of pyruvate dehydrogenase (PDH) complex";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Signaling by Retinoic Acid";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" maker-scaffold367size190875-augustus-gene-0.14-mRNA-1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity" augustus-scaffold343size209053-processed-gene-1.0-mRNA-1 15 Reactome: R-HSA-204174;Reactome: R-HSA-4615885;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;Reactome: R-HSA-5362517;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00310+1.2.4.2;Reactome: R-HSA-2187335;Reactome: R-HSA-71403;KEGG: 00380+1.2.4.2;Reactome: R-HSA-2453902;KEGG: 00310+2.3.1.61;MetaCyc: PWY-5084 "Regulation of pyruvate dehydrogenase (PDH) complex";"SUMOylation of DNA replication proteins";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Tryptophan metabolism";"Lysine catabolism";"Lysine degradation";"The retinoid cycle in cones (daylight vision)";"Citric acid cycle (TCA cycle)";"Tryptophan metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" maker-scaffold210size338753-augustus-gene-2.1-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold169size953240-augustus-gene-8.21-mRNA-1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation" maker-scaffold151size424828-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" maker-scaffold373size184716-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-8953750;Reactome: R-HSA-4551638 "Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins" maker-scaffold2254size10528-augustus-gene-0.0-mRNA-1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" maker-scaffold11size1424826-augustus-gene-2.10-mRNA-1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-381426;Reactome: R-HSA-3769402 "Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Deactivation of the beta-catenin transactivating complex" augustus-scaffold1481size18987-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-204626;Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Hypusine synthesis from eIF5A-lysine";"Ub-specific processing proteases";"Translesion Synthesis by POLH" maker-scaffold73size681921-augustus-gene-5.2-mRNA-1 1 Reactome: R-HSA-5689603 "UCH proteinases" maker-scaffold402size240807-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold9764size7771-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold136size447168-augustus-gene-3.3-mRNA-1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" maker-scaffold29size1057726-augustus-gene-8.3-mRNA-1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" maker-scaffold14size1670589-augustus-gene-15.2-mRNA-1 24 Reactome: R-HSA-422356;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-9634600;Reactome: R-HSA-4420097;Reactome: R-HSA-5610780;Reactome: R-HSA-8853659;Reactome: R-HSA-9010642;Reactome: R-HSA-5610783;Reactome: R-HSA-180024;KEGG: 04150+2.7.11.11;Reactome: R-HSA-111931;Reactome: R-HSA-8963896;Reactome: R-HSA-381676;Reactome: R-HSA-163358;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-163560;Reactome: R-HSA-392517;Reactome: R-HSA-5621575 "Regulation of insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"VEGFA-VEGFR2 Pathway";"Degradation of GLI1 by the proteasome";"RET signaling";"ROBO receptors bind AKAP5";"Degradation of GLI2 by the proteasome";"DARPP-32 events";"mTOR signaling pathway";"PKA-mediated phosphorylation of CREB";"HDL assembly";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA-mediated phosphorylation of key metabolic factors";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Triglyceride catabolism";"Rap1 signalling";"CD209 (DC-SIGN) signaling" maker-scaffold31size1053862-augustus-gene-8.0-mRNA-1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" maker-scaffold86size613819-augustus-gene-3.12-mRNA-1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" maker-scaffold9size1444705-augustus-gene-11.1-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold209size335547-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold86size613819-augustus-gene-4.2-mRNA-1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" maker-scaffold6size1916839-augustus-gene-3.5-mRNA-1 10 Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3928662 "RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EPHB-mediated forward signaling" maker-scaffold20size1234842-augustus-gene-4.14-mRNA-1 5 MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692 "Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Fe(II) oxidation" maker-scaffold242size299879-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold73size681921-augustus-gene-1.2-mRNA-1 6 Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" maker-scaffold5737size7703-augustus-gene-0.0-mRNA-1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" maker-scaffold23size1161859-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold42size1661181-augustus-gene-3.8-mRNA-1 3 Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism" maker-scaffold120size483217-augustus-gene-3.6-mRNA-1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" maker-scaffold6size1916839-augustus-gene-6.0-mRNA-1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" maker-scaffold443size134888-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold89size602897-augustus-gene-1.3-mRNA-1 23 Reactome: R-HSA-73762;Reactome: R-HSA-73863;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;Reactome: R-HSA-5250924;KEGG: 00270+1.1.1.37;Reactome: R-HSA-73772;MetaCyc: PWY-6728;Reactome: R-HSA-427413;MetaCyc: PWY-1622;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-7383;Reactome: R-HSA-70263 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"TCA cycle II (plants and fungi)";"Methane metabolism";"B-WICH complex positively regulates rRNA expression";"Cysteine and methionine metabolism";"RNA Polymerase I Promoter Escape";"Methylaspartate cycle";"NoRC negatively regulates rRNA expression";"Formaldehyde assimilation I (serine pathway)";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis" maker-scaffold19size1242042-augustus-gene-3.8-mRNA-1 4 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" maker-scaffold42size1661181-augustus-gene-2.17-mRNA-1 16 Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174084;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176407 "Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" maker-scaffold1659size16250-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" maker-scaffold18size2240851-augustus-gene-20.0-mRNA-1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" maker-scaffold45size832949-augustus-gene-3.2-mRNA-1 6 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" maker-scaffold386size172899-augustus-gene-0.8-mRNA-1 4 Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829 "ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" maker-scaffold279size261100-augustus-gene-1.5-mRNA-1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" maker-scaffold156size419509-augustus-gene-3.24-mRNA-1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" maker-scaffold35size976498-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold9size1444705-augustus-gene-0.3-mRNA-1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Neutrophil degranulation";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6" maker-scaffold299size238480-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold138size440403-augustus-gene-3.4-mRNA-1 33 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-191859;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"snRNP Assembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"HCMV Late Events" maker-scaffold2size2657229-augustus-gene-20.3-mRNA-1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-4085377 "SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"HCMV Late Events";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins" maker-scaffold2370size9923-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" maker-scaffold590size80074-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" maker-scaffold993size33622-augustus-gene-0.2-mRNA-1 3 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" maker-scaffold210size338753-augustus-gene-2.4-mRNA-1 3 MetaCyc: PWY-6367;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.78 "D-myo-inositol-5-phosphate metabolism";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" maker-scaffold66size1200099-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" maker-scaffold72size687670-augustus-gene-3.2-mRNA-1 2 Reactome: R-HSA-6793080;Reactome: R-HSA-2151201 "rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis" maker-scaffold4506size14681-augustus-gene-0.2-mRNA-1 6 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427359 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression" maker-scaffold176size389526-augustus-gene-1.2-mRNA-1 3 Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361 "Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins" maker-scaffold105size529344-augustus-gene-4.5-mRNA-1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" maker-scaffold8size1945031-augustus-gene-6.6-mRNA-1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" maker-scaffold268size268435-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374;Reactome: R-HSA-162699 "Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Synthesis of dolichyl-phosphate mannose" maker-scaffold1881size15059-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" maker-scaffold5277size8151-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" maker-scaffold181size378167-augustus-gene-2.3-mRNA-1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" maker-scaffold284size253718-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" maker-scaffold19size1242042-augustus-gene-2.5-mRNA-1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" maker-scaffold18size2240851-augustus-gene-10.0-mRNA-1 1 MetaCyc: PWY-6938 "NADH repair" maker-scaffold189size362018-augustus-gene-2.3-mRNA-1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5358565;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" maker-scaffold946size36271-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" maker-scaffold855size42418-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-5675221;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000 "Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation" maker-scaffold136size447168-augustus-gene-3.19-mRNA-1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" maker-scaffold2713size8441-augustus-gene-0.1-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" maker-scaffold1514size18258-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-5678771;Reactome: R-HSA-1989781;Reactome: R-HSA-382556 "Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression";"ABC-family proteins mediated transport" maker-scaffold2size2657229-augustus-gene-3.5-mRNA-1 1 Reactome: R-HSA-977225 "Amyloid fiber formation" maker-scaffold13size1375079-augustus-gene-6.1-mRNA-1 7 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway" maker-scaffold43size857109-augustus-gene-6.1-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold32size1041436-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" maker-scaffold3432size5619-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" maker-scaffold1410size19988-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold337size211899-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold424size145378-augustus-gene-0.6-mRNA-1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" maker-scaffold6101size2784-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" maker-scaffold19size1242042-augustus-gene-2.1-mRNA-1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" maker-scaffold258size282563-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes" maker-scaffold26size1667613-augustus-gene-8.2-mRNA-1 4 Reactome: R-HSA-446199;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-4755583 "Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Defective DOLK causes DOLK-CDG (CDG-1m)" maker-scaffold157size419459-augustus-gene-2.3-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold85size629767-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold1023size31993-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" maker-scaffold8size1945031-augustus-gene-3.3-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold42size1661181-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold48size811354-augustus-gene-5.1-mRNA-1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" maker-scaffold13size1375079-augustus-gene-11.5-mRNA-1 6 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway" maker-scaffold99size561911-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" maker-scaffold18648size7229-augustus-gene-0.1-mRNA-1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706 "L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" maker-scaffold283size256806-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" maker-scaffold828size44283-augustus-gene-0.1-mRNA-1 11 Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565 "Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" maker-scaffold2931size7690-augustus-gene-0.0-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" augustus-scaffold1364size20936-processed-gene-0.2-mRNA-1 2 MetaCyc: PWY-7801;Reactome: R-HSA-3299685 "N-end rule pathway I (prokaryotic)";"Detoxification of Reactive Oxygen Species" maker-scaffold399size161796-augustus-gene-0.10-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold13size1375079-augustus-gene-9.5-mRNA-1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" maker-scaffold228size313446-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold83size640441-augustus-gene-5.1-mRNA-1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" maker-scaffold261size276640-augustus-gene-1.11-mRNA-1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" maker-scaffold75size670735-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-611105 "Respiratory electron transport" maker-scaffold34size991984-augustus-gene-6.5-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold79size709353-augustus-gene-3.0-mRNA-1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" augustus-scaffold1193size24721-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold73size681921-augustus-gene-5.4-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold2size2657229-augustus-gene-25.28-mRNA-1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" maker-scaffold1269size22704-augustus-gene-0.1-mRNA-1 12 Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-167243 "Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery" maker-scaffold1540size17866-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" maker-scaffold190size360960-augustus-gene-2.1-mRNA-1 30 Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-2122947;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-202424;Reactome: R-HSA-2644606;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-2894862;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-1170546;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-917937;Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-9604323;Reactome: R-HSA-400253;Reactome: R-HSA-2644607;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783 "SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Downstream TCR signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Prolactin receptor signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Iron uptake and transport";"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Negative regulation of NOTCH4 signaling";"Circadian Clock";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome" maker-scaffold97size566834-augustus-gene-4.4-mRNA-1 56 Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-69017 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6" maker-scaffold416size148305-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" maker-scaffold46size820514-augustus-gene-5.1-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold156size419509-augustus-gene-3.20-mRNA-1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" maker-scaffold218size326752-augustus-gene-2.9-mRNA-1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" maker-scaffold4794size3253-augustus-gene-0.0-mRNA-1 56 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)" maker-scaffold299size238480-augustus-gene-0.0-mRNA-1 6 MetaCyc: PWY-5497;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-7442 "Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis" maker-scaffold6size1916839-augustus-gene-5.3-mRNA-1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" maker-scaffold16size1255579-augustus-gene-11.11-mRNA-1 3 MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403 "Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione synthesis and recycling" maker-scaffold223size319359-augustus-gene-2.8-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold9size1444705-augustus-gene-4.24-mRNA-1 6 Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis" maker-scaffold169size953240-augustus-gene-5.16-mRNA-1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" maker-scaffold820size45298-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold36size1013817-augustus-gene-7.4-mRNA-1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" maker-scaffold566size86364-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" augustus-scaffold1108size28612-processed-gene-0.1-mRNA-1 8 Reactome: R-HSA-194840;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;Reactome: R-HSA-3371453;Reactome: R-HSA-416482;MetaCyc: PWY-7219;Reactome: R-HSA-193648 "Rho GTPase cycle";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Regulation of HSF1-mediated heat shock response";"G alpha (12/13) signalling events";"Adenosine ribonucleotides de novo biosynthesis";"NRAGE signals death through JNK" maker-scaffold875size40764-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold95size722721-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold89size602897-augustus-gene-1.2-mRNA-1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1" maker-scaffold105size529344-augustus-gene-4.16-mRNA-1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" maker-scaffold28size1079920-augustus-gene-9.7-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold1size2756217-augustus-gene-15.10-mRNA-1 14 Reactome: R-HSA-419771;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764 "Opsins";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination" maker-scaffold269size268280-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold85size629767-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" maker-scaffold47size1319914-augustus-gene-4.2-mRNA-1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" maker-scaffold42size1661181-augustus-gene-9.0-mRNA-1 6 Reactome: R-HSA-70221;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;MetaCyc: PWY-7238;MetaCyc: PWY-6737 "Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Starch and sucrose metabolism";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch degradation V" maker-scaffold237size302539-augustus-gene-2.7-mRNA-1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880 "Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases" maker-scaffold10size1426409-augustus-gene-10.1-mRNA-1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" maker-scaffold847size42943-augustus-gene-0.2-mRNA-1 7 Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" maker-scaffold13size1375079-augustus-gene-8.7-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold237size302539-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold76size663279-augustus-gene-5.2-mRNA-1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" maker-scaffold1285size22463-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation" maker-scaffold38size924328-augustus-gene-2.1-mRNA-1 2 KEGG: 00240+3.6.1.23;KEGG: 00983+3.6.1.23 "Pyrimidine metabolism";"Drug metabolism - other enzymes" maker-scaffold2size2657229-augustus-gene-25.27-mRNA-1 6 KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241 "Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism";"Peroxisomal protein import" maker-scaffold15620size7724-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" maker-scaffold124size587478-augustus-gene-0.1-mRNA-1 3 MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3 "Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism" maker-scaffold10size1426409-augustus-gene-4.2-mRNA-1 7 MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7839;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7841 "Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis" maker-scaffold28size1079920-augustus-gene-9.11-mRNA-1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6 "Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine metabolism" maker-scaffold266size269306-augustus-gene-1.10-mRNA-1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold1290size22226-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" maker-scaffold141size440309-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold5size1727520-augustus-gene-16.2-mRNA-1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" maker-scaffold1605size16898-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" maker-scaffold8575size7939-augustus-gene-0.0-mRNA-1 8 KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5173105 "Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation" maker-scaffold165size402902-augustus-gene-3.4-mRNA-1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex" maker-scaffold235size305606-augustus-gene-2.13-mRNA-1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-6784531 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus" maker-scaffold65size703589-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" maker-scaffold157size419459-augustus-gene-3.24-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold4536size3431-augustus-gene-0.0-mRNA-1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" maker-scaffold25size1130848-augustus-gene-5.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold4size1754260-augustus-gene-12.8-mRNA-1 13 MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7410;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7736;KEGG: 00900+2.5.1.10+2.5.1.1 "All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Ipsdienol biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Stellatic acid biosynthesis";"Terpenoid backbone biosynthesis" maker-scaffold447size134401-augustus-gene-0.0-mRNA-1 10 MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7112 "Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification" maker-scaffold42size1661181-augustus-gene-13.6-mRNA-1 5 Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695 "Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Neutrophil degranulation" maker-scaffold411size152019-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold161size412613-augustus-gene-2.3-mRNA-1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" maker-scaffold9size1444705-augustus-gene-0.1-mRNA-1 57 Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" maker-scaffold218size326752-augustus-gene-2.18-mRNA-1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" maker-scaffold3597size10854-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold1145size26688-augustus-gene-0.0-mRNA-1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" maker-scaffold231size308180-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold157size419459-augustus-gene-3.9-mRNA-1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" maker-scaffold48size811354-augustus-gene-5.4-mRNA-1 40 KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5109;MetaCyc: PWY-7606;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5177;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7094;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-6883;MetaCyc: PWY-5138;MetaCyc: PWY-6944;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7656;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-6945;MetaCyc: PWY-6435;MetaCyc: PWY-6583;MetaCyc: PWY-7401 "Carbon fixation pathways in prokaryotes";"Toluene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fermentation to 2-methylbutanoate";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"beta-Alanine metabolism";"2-methylpropene degradation";"Limonene and pinene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Valine, leucine and isoleucine degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid salvage";"Benzoate degradation";"Aminobenzoate degradation";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Caprolactam degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Propanoate metabolism";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Androstenedione degradation";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Methyl tert-butyl ether degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)" maker-scaffold76size663279-augustus-gene-4.2-mRNA-1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780 "Hedgehog 'off' state";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome" maker-scaffold140size439629-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" maker-scaffold17size1249603-augustus-gene-11.20-mRNA-1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" maker-scaffold10size1426409-augustus-gene-2.2-mRNA-1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" maker-scaffold17424size7583-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold931size37200-augustus-gene-0.3-mRNA-1 2 MetaCyc: PWY-6164;KEGG: 00400+4.2.3.4 "3-dehydroquinate biosynthesis I";"Phenylalanine, tyrosine and tryptophan biosynthesis" maker-scaffold14size1670589-augustus-gene-15.19-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold280size266829-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-71384 "Ethanol oxidation" maker-scaffold281size259073-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-8949613 "Cristae formation" maker-scaffold1size2756217-augustus-gene-18.2-mRNA-1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis" maker-scaffold335size212668-augustus-gene-0.2-mRNA-1 9 Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-110314 "Dual incision in TC-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex" maker-scaffold235size305606-augustus-gene-2.11-mRNA-1 7 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22 "Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism" maker-scaffold302size236263-augustus-gene-1.3-mRNA-1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" maker-scaffold180size376838-augustus-gene-0.5-mRNA-1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold400size160987-augustus-gene-0.4-mRNA-1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" augustus-scaffold1568size17327-processed-gene-0.0-mRNA-1 10 MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+2.7.2.3;MetaCyc: PWY-7003;MetaCyc: PWY-6886;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6901;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-8004 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway I" maker-scaffold43size857109-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold87size608750-augustus-gene-4.4-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold267size269091-augustus-gene-1.13-mRNA-1 10 Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-445144;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751 "WNT mediated activation of DVL";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Signal transduction by L1";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity" maker-scaffold209size335547-augustus-gene-2.4-mRNA-1 7 MetaCyc: PWY-7807;MetaCyc: PWY-6605;MetaCyc: PWY-7805;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6610 "Glyphosate degradation III";"Adenine and adenosine salvage II";"(aminomethyl)phosphonate degradation";"Purine salvage";"Neutrophil degranulation";"Purine metabolism";"Adenine salvage" maker-scaffold192size359585-augustus-gene-0.9-mRNA-1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" maker-scaffold76size663279-augustus-gene-4.22-mRNA-1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" maker-scaffold169size953240-augustus-gene-8.3-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold670size60319-augustus-gene-0.2-mRNA-1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" maker-scaffold16size1255579-augustus-gene-11.20-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" maker-scaffold1281size22565-augustus-gene-0.1-mRNA-1 3 KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" maker-scaffold47size1319914-augustus-gene-8.6-mRNA-1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold137size446348-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" maker-scaffold4size1754260-augustus-gene-4.17-mRNA-1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" maker-scaffold256size285501-augustus-gene-0.5-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold275size262729-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" augustus-scaffold3760size4990-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035 "RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" maker-scaffold805size46428-augustus-gene-0.0-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold110size515606-augustus-gene-3.15-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold48size811354-augustus-gene-7.6-mRNA-1 5 Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781 "ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression" maker-scaffold157size419459-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" maker-scaffold200size345481-augustus-gene-2.20-mRNA-1 8 Reactome: R-HSA-917937;Reactome: R-HSA-1445148;Reactome: R-HSA-5619060;Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-425410;Reactome: R-HSA-5619049;Reactome: R-HSA-5655799 "Iron uptake and transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Defective CP causes aceruloplasminemia (ACERULOP)";"VxPx cargo-targeting to cilium";"Insulin processing";"Metal ion SLC transporters";"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)";"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)" maker-scaffold1size2756217-augustus-gene-4.24-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold138size440403-augustus-gene-3.2-mRNA-1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" maker-scaffold25size1130848-augustus-gene-2.3-mRNA-1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" maker-scaffold75size670735-augustus-gene-3.6-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold53size789746-augustus-gene-6.2-mRNA-1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)" augustus-scaffold1045size31166-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold6size1916839-augustus-gene-9.2-mRNA-1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228 "Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix" maker-scaffold36size1013817-augustus-gene-3.2-mRNA-1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" maker-scaffold19size1242042-augustus-gene-5.10-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold1866size13985-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold260size277064-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" augustus-scaffold1044size31238-processed-gene-0.0-mRNA-1 26 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7115;MetaCyc: PWY-6969;MetaCyc: PWY-7400;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5154;MetaCyc: PWY-7383;Reactome: R-HSA-70263;MetaCyc: PWY-4361;KEGG: 00220+1.2.1.38;MetaCyc: PWY-5690;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7174;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-1622;MetaCyc: PWY-561;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;Reactome: R-HSA-6791226 "Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arginine biosynthesis IV (archaebacteria)";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Arginine biosynthesis";"TCA cycle II (plants and fungi)";"Methane metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold43size857109-augustus-gene-4.25-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold643size65972-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" maker-scaffold47size1319914-augustus-gene-2.5-mRNA-1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" maker-scaffold11size1424826-augustus-gene-10.2-mRNA-1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" maker-scaffold45size832949-augustus-gene-7.14-mRNA-1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" maker-scaffold31size1053862-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold499size127699-augustus-gene-0.6-mRNA-1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" augustus-scaffold1116size28143-processed-gene-0.0-mRNA-1 7 Reactome: R-HSA-2408522;MetaCyc: PWY-4361;Reactome: R-HSA-379716;KEGG: 00270+5.3.1.23;KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10;MetaCyc: PWY-7174 "Selenoamino acid metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cytosolic tRNA aminoacylation";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" maker-scaffold355size200716-augustus-gene-1.1-mRNA-1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" maker-scaffold9size1444705-augustus-gene-9.0-mRNA-1 15 Reactome: R-HSA-9665245;Reactome: R-HSA-9664565;Reactome: R-HSA-1227986;Reactome: R-HSA-9665249;Reactome: R-HSA-5637810;Reactome: R-HSA-9652282;Reactome: R-HSA-9665247;Reactome: R-HSA-1236382;Reactome: R-HSA-9665246;Reactome: R-HSA-9665244;Reactome: R-HSA-9634285;Reactome: R-HSA-8863795;Reactome: R-HSA-9665233;Reactome: R-HSA-9665251;Reactome: R-HSA-9665250 "Resistance of ERBB2 KD mutants to tesevatinib";"Signaling by ERBB2 KD Mutants";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to afatinib";"Constitutive Signaling by EGFRvIII";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to sapitinib";"Constitutive Signaling by Overexpressed ERBB2";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to AEE788" maker-scaffold58size769326-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold200size345481-augustus-gene-2.11-mRNA-1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055 "Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis" maker-scaffold161size412613-augustus-gene-0.1-mRNA-1 7 Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-72649 "Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation" maker-scaffold292size244886-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold11size1424826-augustus-gene-10.0-mRNA-1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" maker-scaffold11size1424826-augustus-gene-4.1-mRNA-1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" maker-scaffold494size108766-augustus-gene-0.1-mRNA-1 57 Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761 "Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"ER-Phagosome pathway";"G2/M Checkpoints";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling" maker-scaffold2size2657229-augustus-gene-6.5-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold16size1255579-augustus-gene-11.8-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold72size687670-augustus-gene-5.20-mRNA-1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" maker-scaffold65size703589-augustus-gene-6.8-mRNA-1 11 Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2173796;Reactome: R-HSA-9013508;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-210744 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" maker-scaffold65size703589-augustus-gene-6.2-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold1762size15112-augustus-gene-0.0-mRNA-1 24 Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-416482;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-500657 "Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"G alpha (12/13) signalling events";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors" maker-scaffold37size976698-augustus-gene-6.8-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold238size302402-augustus-gene-2.10-mRNA-1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" maker-scaffold352size202783-augustus-gene-1.9-mRNA-1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" maker-scaffold33size1007119-augustus-gene-4.6-mRNA-1 33 MetaCyc: PWY-5078;MetaCyc: PWY-1801;MetaCyc: PWY-7798;MetaCyc: PWY-5486;MetaCyc: PWY-5057;KEGG: 00980+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5480;MetaCyc: PWY-5076;MetaCyc: PWY-6333;MetaCyc: PWY-6313;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6802;KEGG: 00625+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-5082;KEGG: 00680+1.1.1.284;KEGG: 00260+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-7111;MetaCyc: PWY-6871;KEGG: 00350+1.1.1.1;MetaCyc: PWY-6587;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7396;Reactome: R-HSA-71384;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00010+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5751 "L-isoleucine degradation II";"Formaldehyde oxidation II (glutathione-dependent)";"Protein S-nitrosylation and denitrosylation";"Pyruvate fermentation to ethanol II";"L-valine degradation II";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"L-tryptophan degradation V (side chain pathway)";"Pyruvate fermentation to ethanol I";"L-leucine degradation III";"Acetaldehyde biosynthesis I";"Serotonin degradation";"Fatty acid degradation";"Salidroside biosynthesis";"Chloroalkane and chloroalkene degradation";"(S)-propane-1,2-diol degradation";"L-methionine degradation III";"Methane metabolism";"Glycine, serine and threonine metabolism";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to isobutanol (engineered)";"3-methylbutanol biosynthesis (engineered)";"Tyrosine metabolism";"Pyruvate fermentation to ethanol III";"Naphthalene degradation";"Butanol and isobutanol biosynthesis (engineered)";"Ethanol oxidation";"alpha-Linolenic acid metabolism";"L-phenylalanine degradation III";"Glycolysis / Gluconeogenesis";"Retinol metabolism";"Chitin degradation to ethanol";"Phenylethanol biosynthesis" maker-scaffold13size1375079-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" maker-scaffold222size322023-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold1641size23307-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" maker-scaffold2size2657229-augustus-gene-1.10-mRNA-1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" maker-scaffold6111size10333-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" maker-scaffold13size1375079-augustus-gene-4.8-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold20size1234842-augustus-gene-11.15-mRNA-1 6 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-5662702 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Melanin biosynthesis" maker-scaffold48size811354-augustus-gene-4.13-mRNA-1 4 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;Reactome: R-HSA-6782861;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Folate biosynthesis" maker-scaffold80size1421260-augustus-gene-10.5-mRNA-1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" maker-scaffold12size1412574-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" maker-scaffold229size310297-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" maker-scaffold3size2782310-augustus-gene-6.5-mRNA-1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" maker-scaffold3size2782310-augustus-gene-7.4-mRNA-1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" maker-scaffold241size304314-augustus-gene-2.3-mRNA-1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" maker-scaffold14size1670589-augustus-gene-14.0-mRNA-1 5 KEGG: 00230+2.7.4.10;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" maker-scaffold4size1754260-augustus-gene-14.1-mRNA-1 19 Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275 "Retinoid metabolism and transport";"Scavenging by Class H Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Scavenging by Class B Receptors";"Chylomicron remodeling";"LDL remodeling";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Chylomicron assembly";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"VLDL assembly";"Post-translational protein phosphorylation" maker-scaffold145size712617-augustus-gene-2.6-mRNA-1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" maker-scaffold3size2782310-augustus-gene-4.19-mRNA-1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" augustus-scaffold18006size7630-processed-gene-0.0-mRNA-1 26 Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-5663220;Reactome: R-HSA-389977 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Recycling pathway of L1";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Kinesins";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"RHO GTPases Activate Formins";"Post-chaperonin tubulin folding pathway" maker-scaffold11size1424826-augustus-gene-7.0-mRNA-1 4 Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" maker-scaffold119size489016-augustus-gene-3.1-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold1size2756217-augustus-gene-21.6-mRNA-1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation" maker-scaffold17size1249603-augustus-gene-11.29-mRNA-1 8 MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "ATP biosynthesis";"Insulin receptor recycling";"Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" maker-scaffold5220size7628-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" maker-scaffold1size2756217-augustus-gene-17.2-mRNA-1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" maker-scaffold280size266829-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold1004size33006-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold38size924328-augustus-gene-7.1-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold45size832949-augustus-gene-6.1-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold23size1161859-augustus-gene-0.4-mRNA-1 4 Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59 "Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism" maker-scaffold252size289391-augustus-gene-1.6-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold8size1945031-augustus-gene-16.6-mRNA-1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" maker-scaffold488size114634-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold227size314013-augustus-gene-2.9-mRNA-1 14 Reactome: R-HSA-399997;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-500657;Reactome: R-HSA-1855204;Reactome: R-HSA-418217;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;Reactome: R-HSA-434316;MetaCyc: PWY-6367;MetaCyc: PWY-6351 "Acetylcholine regulates insulin secretion";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Ca2+ pathway";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"Synthesis of IP3 and IP4 in the cytosol";"G beta:gamma signalling through PLC beta";"PLC beta mediated events";"Inositol phosphate metabolism";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" maker-scaffold96size574823-augustus-gene-3.11-mRNA-1 1 Reactome: R-HSA-264876 "Insulin processing" maker-scaffold1040size31327-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" maker-scaffold210size338753-augustus-gene-2.15-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold13size1375079-augustus-gene-8.2-mRNA-1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" maker-scaffold129size456722-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-74217 "Purine salvage" augustus-scaffold2703size8470-processed-gene-0.4-mRNA-1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" maker-scaffold12size1412574-augustus-gene-11.2-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold131size455331-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold4746size9789-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold47size1319914-augustus-gene-10.4-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold17size1249603-augustus-gene-11.1-mRNA-1 1 Reactome: R-HSA-8949613 "Cristae formation" maker-scaffold78size655360-augustus-gene-4.0-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold15size1261043-augustus-gene-11.0-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"ChREBP activates metabolic gene expression" maker-scaffold59size767954-augustus-gene-3.8-mRNA-1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" maker-scaffold6size1916839-augustus-gene-14.2-mRNA-1 3 Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511 "Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination" maker-scaffold361size197669-augustus-gene-1.5-mRNA-1 14 KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;Reactome: R-HSA-8964208;Reactome: R-HSA-71240;Reactome: R-HSA-8964539;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-1187;MetaCyc: PWY-6842 "Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Tryptophan catabolism";"Glutamate and glutamine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Glutathione-mediated detoxification II" maker-scaffold9size1444705-augustus-gene-12.3-mRNA-1 10 Reactome: R-HSA-111457;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111459;Reactome: R-HSA-5628897 "Release of apoptotic factors from the mitochondria";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Metabolic Genes" maker-scaffold38size924328-augustus-gene-0.1-mRNA-1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" maker-scaffold77size662763-augustus-gene-5.14-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold3657size9800-augustus-gene-0.0-mRNA-1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" maker-scaffold5size1727520-augustus-gene-5.5-mRNA-1 11 Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" maker-scaffold101size554424-augustus-gene-3.0-mRNA-1 14 MetaCyc: PWY-2201;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;KEGG: 00460+2.1.2.1;Reactome: R-HSA-196757;MetaCyc: PWY-181;MetaCyc: PWY-3841 "Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"One carbon pool by folate";"Glycine betaine degradation I";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Cyanoamino acid metabolism";"Metabolism of folate and pterines";"Photorespiration ";"Folate transformations II (plants)" maker-scaffold9size1444705-augustus-gene-5.6-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold165size402902-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold138size440403-augustus-gene-3.14-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold80size1421260-augustus-gene-4.0-mRNA-1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" maker-scaffold526size170922-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" maker-scaffold1665size16176-augustus-gene-0.0-mRNA-1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" maker-scaffold2599size14382-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold68size696256-augustus-gene-6.2-mRNA-1 6 Reactome: R-HSA-1483148;MetaCyc: PWY-7817;MetaCyc: PWY-5269;MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166 "Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA" maker-scaffold463size137807-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold9size1444705-augustus-gene-8.2-mRNA-1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" maker-scaffold235size305606-augustus-gene-2.5-mRNA-1 1 Reactome: R-HSA-8849175 "Threonine catabolism" augustus-scaffold1319size21677-processed-gene-0.0-mRNA-1 4 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" maker-scaffold271size267669-augustus-gene-1.11-mRNA-1 5 Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold463size137807-augustus-gene-0.4-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold82size640827-augustus-gene-1.1-mRNA-1 34 Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-8939236;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-69273;Reactome: R-HSA-69231;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167200;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-69202;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-69656;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-73772 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin D associated events in G1";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"mRNA Capping";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual incision in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Cyclin E associated events during G1/S transition";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape" maker-scaffold120size483217-augustus-gene-3.14-mRNA-1 4 Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" maker-scaffold2409size9749-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" maker-scaffold136size447168-augustus-gene-3.15-mRNA-1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6783310 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Fanconi Anemia Pathway" maker-scaffold187size362697-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold72size687670-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" maker-scaffold8size1945031-augustus-gene-10.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold246size295413-augustus-gene-2.9-mRNA-1 57 Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768 "Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" maker-scaffold158size418592-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" maker-scaffold82size640827-augustus-gene-0.2-mRNA-1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" maker-scaffold3size2782310-augustus-gene-4.6-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold275size262729-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-176974 "Unwinding of DNA" maker-scaffold70size694644-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold272size266709-augustus-gene-1.6-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" augustus-scaffold1765size15098-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" maker-scaffold6size1916839-augustus-gene-13.6-mRNA-1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" maker-scaffold426size144818-augustus-gene-0.9-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold101size554424-augustus-gene-4.1-mRNA-1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold2size2657229-augustus-gene-15.2-mRNA-1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" maker-scaffold1size2756217-augustus-gene-15.11-mRNA-1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" maker-scaffold2size2657229-augustus-gene-2.4-mRNA-1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" maker-scaffold2size2657229-augustus-gene-18.1-mRNA-1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" maker-scaffold26size1667613-augustus-gene-5.5-mRNA-1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" maker-scaffold156size419509-augustus-gene-2.1-mRNA-1 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" maker-scaffold4size1754260-augustus-gene-16.24-mRNA-1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"DARPP-32 events" maker-scaffold4648size7680-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER" maker-scaffold48size811354-augustus-gene-3.3-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold34size991984-augustus-gene-0.0-mRNA-1 7 Reactome: R-HSA-389661;KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" maker-scaffold10size1426409-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-3295583 "TRP channels" maker-scaffold38size924328-augustus-gene-7.3-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold5size1727520-augustus-gene-13.2-mRNA-1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494 "Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism";"Choline degradation IV" maker-scaffold6size1916839-augustus-gene-10.4-mRNA-1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" augustus-scaffold748size51603-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" maker-scaffold110size515606-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold23size1161859-augustus-gene-4.1-mRNA-1 6 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling";"Collagen degradation";"Non-integrin membrane-ECM interactions" maker-scaffold351size203122-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-5689877;Reactome: R-HSA-5205685 "Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Amyloid fiber formation";"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy" maker-scaffold9size1444705-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" augustus-scaffold689size58138-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-8866427;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-6807505;Reactome: R-HSA-381426 "VLDLR internalisation and degradation";"Post-translational protein phosphorylation";"LDL clearance";"RNA polymerase II transcribes snRNA genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" maker-scaffold76size663279-augustus-gene-4.10-mRNA-1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" maker-scaffold3size2782310-augustus-gene-9.3-mRNA-1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" maker-scaffold204size341257-augustus-gene-2.6-mRNA-1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" maker-scaffold256size285501-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold322size219464-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5679001;MetaCyc: PWY-6972;Reactome: R-HSA-189483 "ABC-family proteins mediated transport";"Defective ABCC2 causes Dubin-Johnson syndrome";"Oleandomycin activation/inactivation";"Heme degradation" maker-scaffold7530size8110-augustus-gene-0.0-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold375size184108-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" maker-scaffold2size2657229-augustus-gene-24.3-mRNA-1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" maker-scaffold12size1412574-augustus-gene-5.0-mRNA-1 11 KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-5675;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6964;MetaCyc: PWY-6963 "Nitrogen metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle II";"Ammonia assimilation cycle I" maker-scaffold496size109118-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5620924 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"Intraflagellar transport" maker-scaffold2size2657229-augustus-gene-18.7-mRNA-1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" maker-scaffold896size39288-augustus-gene-0.0-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold192size359585-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" maker-scaffold255size285696-augustus-gene-0.4-mRNA-1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" maker-scaffold82size640827-augustus-gene-0.4-mRNA-1 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" maker-scaffold47size1319914-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold11size1424826-augustus-gene-8.2-mRNA-1 30 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-5696395;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-2564830;Reactome: R-HSA-6796648;Reactome: R-HSA-75953 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Cytosolic iron-sulfur cluster assembly";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation" maker-scaffold306size232476-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" maker-scaffold12size1412574-augustus-gene-2.9-mRNA-1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" maker-scaffold834size43895-augustus-gene-0.3-mRNA-1 6 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2 "Mitochondrial protein import";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Photosynthesis";"Oxidative phosphorylation" maker-scaffold271size267669-augustus-gene-1.4-mRNA-1 16 MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-2221;MetaCyc: PWY-1622 "Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis";"Rubisco shunt";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)" maker-scaffold441size150191-augustus-gene-0.6-mRNA-1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" augustus-scaffold3363size5820-processed-gene-0.0-mRNA-1 4 KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188 "Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)" maker-scaffold2size2657229-augustus-gene-25.20-mRNA-1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" maker-scaffold2size2657229-augustus-gene-18.4-mRNA-1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" maker-scaffold271size267669-augustus-gene-1.5-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" augustus-scaffold1101size28874-processed-gene-0.0-mRNA-1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling" maker-scaffold14size1670589-augustus-gene-10.2-mRNA-1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" maker-scaffold77size662763-augustus-gene-5.9-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold382size176025-augustus-gene-0.9-mRNA-1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" maker-scaffold3705size5130-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold193size358747-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold212size330836-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" maker-scaffold1size2756217-augustus-gene-14.6-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold14size1670589-augustus-gene-9.6-mRNA-1 11 KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8053;MetaCyc: PWY-8052;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-7782 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis II";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Plasmalogen biosynthesis" maker-scaffold45size832949-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" maker-scaffold9size1444705-augustus-gene-4.6-mRNA-1 3 MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" maker-scaffold14size1670589-augustus-gene-10.7-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold34size991984-augustus-gene-8.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold13size1375079-augustus-gene-9.4-mRNA-1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" maker-scaffold48size811354-augustus-gene-7.13-mRNA-1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold279size261100-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold397size365563-augustus-gene-2.11-mRNA-1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" maker-scaffold12size1412574-augustus-gene-10.1-mRNA-1 7 Reactome: R-HSA-1483226;MetaCyc: PWY-6351;MetaCyc: PWY-7625;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11 "Synthesis of PI";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system" maker-scaffold1448size19470-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold237size302539-augustus-gene-2.9-mRNA-1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" maker-scaffold6size1916839-augustus-gene-18.0-mRNA-1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" maker-scaffold2size2657229-augustus-gene-1.1-mRNA-1 6 Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+4.1.1.21;KEGG: 00230+6.3.2.6 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism" maker-scaffold136size447168-augustus-gene-1.3-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold2065size11992-augustus-gene-0.1-mRNA-1 6 MetaCyc: PWY-622;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-5067;Reactome: R-HSA-189085 "Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Digestion of dietary carbohydrate" maker-scaffold1422size19848-augustus-gene-0.0-mRNA-1 6 Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neutrophil degranulation";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER" maker-scaffold86size613819-augustus-gene-5.5-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold42size1661181-augustus-gene-2.11-mRNA-1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" maker-scaffold344size208274-augustus-gene-0.0-mRNA-1 5 MetaCyc: PWY-6012-1;MetaCyc: PWY-6289;Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012 "Acyl carrier protein activation";"Petrobactin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism" maker-scaffold14size1670589-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" maker-scaffold48size811354-augustus-gene-7.8-mRNA-1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" maker-scaffold99size561911-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold634size71122-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" maker-scaffold99size561911-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold156size419509-augustus-gene-3.11-mRNA-1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis" maker-scaffold264size273138-augustus-gene-1.9-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold875size40764-augustus-gene-0.2-mRNA-1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607761 "Neddylation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling" augustus-scaffold633size67688-processed-gene-0.0-mRNA-1 34 KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-7382;MetaCyc: PWY-7126;Reactome: R-HSA-6783310;MetaCyc: PWY-181;Reactome: R-HSA-379716;Reactome: R-HSA-71403;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00220+1.4.1.2;MetaCyc: PWY-6728;Reactome: R-HSA-389661;Reactome: R-HSA-4615885;KEGG: 00430+1.4.1.2;MetaCyc: PWY-5497;KEGG: 00680+2.1.2.1;MetaCyc: PWY-6987;MetaCyc: PWY-3661-1;KEGG: 00785+2.8.1.8;Reactome: R-HSA-2408522;MetaCyc: PWY-1622;KEGG: 00250+1.4.1.2;MetaCyc: PWY-2201;MetaCyc: PWY-6700;KEGG: 00260+2.1.2.1;MetaCyc: PWY-5022;MetaCyc: PWY-2161;MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;KEGG: 00970+6.1.1.19;KEGG: 00910+1.4.1.2 "One carbon pool by folate";"Glycine betaine degradation I";"Lipoate biosynthesis and incorporation IV (yeast)";"Ethylene biosynthesis IV (engineered)";"Fanconi Anemia Pathway";"Photorespiration ";"Cytosolic tRNA aminoacylation";"Citric acid cycle (TCA cycle)";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Arginine biosynthesis";"Methylaspartate cycle";"Glyoxylate metabolism and glycine degradation";"SUMOylation of DNA replication proteins";"Taurine and hypotaurine metabolism";"Purine nucleobases degradation II (anaerobic)";"Methane metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Glycine betaine degradation II (mammalian)";"Lipoic acid metabolism";"Selenoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)";"Alanine, aspartate and glutamate metabolism";"Folate transformations I";"Queuosine biosynthesis I (de novo)";"Glycine, serine and threonine metabolism";"4-aminobutanoate degradation V";"Folate polyglutamylation";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Aminoacyl-tRNA biosynthesis";"Nitrogen metabolism" maker-scaffold47size1319914-augustus-gene-12.5-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold36size1013817-augustus-gene-4.24-mRNA-1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" maker-scaffold181size378167-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold208size344337-augustus-gene-2.5-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold546size91324-augustus-gene-0.9-mRNA-1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" maker-scaffold443size134888-augustus-gene-0.10-mRNA-1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" maker-scaffold9size1444705-augustus-gene-8.0-mRNA-1 5 Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Glutathione metabolism" maker-scaffold12size1412574-augustus-gene-7.2-mRNA-1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" maker-scaffold9size1444705-augustus-gene-5.7-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold49size896674-augustus-gene-3.0-mRNA-1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" maker-scaffold258size282563-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold28size1079920-augustus-gene-6.2-mRNA-1 6 MetaCyc: PWY-7817;MetaCyc: PWY-5981;Reactome: R-HSA-425381;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41 "Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"Bicarbonate transporters";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" maker-scaffold92size586643-augustus-gene-4.32-mRNA-1 60 KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;KEGG: 00360+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00280+4.2.1.17;MetaCyc: PWY-1361;MetaCyc: PWY-7094;KEGG: 00362+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00627+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77346;MetaCyc: PWY-7778;KEGG: 00410+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00380+4.2.1.17;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5177;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5109;MetaCyc: PWY-7606;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7779;MetaCyc: PWY-6945;MetaCyc: PWY-6435;MetaCyc: PWY-6583;MetaCyc: PWY-7401;MetaCyc: PWY-6944;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;MetaCyc: PWY-7726;MetaCyc: PWY-7656;MetaCyc: PWY-6946;Reactome: R-HSA-77350;Reactome: R-HSA-77310;KEGG: 00310+4.2.1.17;KEGG: 00640+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-6883;KEGG: 00930+4.2.1.17;MetaCyc: PWY-5138 "Butanoate metabolism";"Fatty acid elongation";"Pyruvate fermentation to hexanol (engineered)";"Phenylalanine metabolism";"Caprolactam degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Benzoate degradation";"Valine, leucine and isoleucine degradation";"Benzoyl-coa degradation I (aerobic)";"Fatty acid salvage";"Benzoate degradation";"Acyl chain remodeling of CL";"Aminobenzoate degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Butanoate metabolism";"alpha-Linolenic acid metabolism";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"2-methylpropene degradation";"beta-Alanine metabolism";"Limonene and pinene degradation";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Valine, leucine and isoleucine degradation";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fermentation to 2-methylbutanoate";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Geraniol degradation";"Fatty acid elongation";"Geraniol degradation";"Methyl tert-butyl ether degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol I";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Androstenedione degradation";"Fatty acid degradation";"Tryptophan metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Spodoptera littoralis pheromone biosynthesis";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Lysine degradation";"Propanoate metabolism";"Fatty acid degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Butanoate metabolism";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Pyruvate fermentation to butanol II (engineered)";"Caprolactam degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)" maker-scaffold494size108766-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" maker-scaffold2176size11107-augustus-gene-0.0-mRNA-1 11 MetaCyc: PWY-3881;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-7456 "Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"Beta-(1,4)-mannan degradation" maker-scaffold351size203122-augustus-gene-0.2-mRNA-1 6 KEGG: 00900+4.1.1.33;MetaCyc: PWY-922;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-446199 "Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Synthesis of Dolichyl-phosphate" maker-scaffold17size1249603-augustus-gene-11.24-mRNA-1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" maker-scaffold187size362697-augustus-gene-2.8-mRNA-1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" maker-scaffold13size1375079-augustus-gene-8.6-mRNA-1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690 "Cilium Assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"HCMV Early Events" maker-scaffold12size1412574-augustus-gene-13.2-mRNA-1 12 MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis";"Methane metabolism";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)" maker-scaffold193size358747-augustus-gene-0.1-mRNA-1 57 Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783 "Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Neutrophil degranulation";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Orc1 removal from chromatin";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome" maker-scaffold8size1945031-augustus-gene-16.2-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold6size1916839-augustus-gene-6.4-mRNA-1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" maker-scaffold1size2756217-augustus-gene-15.7-mRNA-1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" maker-scaffold84size638750-augustus-gene-5.9-mRNA-1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" maker-scaffold1size2756217-augustus-gene-18.0-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold70size694644-augustus-gene-5.12-mRNA-1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-9609523;Reactome: R-HSA-1660661 "Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis" maker-scaffold261size276640-augustus-gene-1.3-mRNA-1 16 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold89size602897-augustus-gene-4.1-mRNA-1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" maker-scaffold1414size19918-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" maker-scaffold13size1375079-augustus-gene-4.18-mRNA-1 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling" maker-scaffold49size896674-augustus-gene-7.6-mRNA-1 4 KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)" maker-scaffold89size602897-augustus-gene-5.18-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold1size2756217-augustus-gene-26.16-mRNA-1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" maker-scaffold207size345476-augustus-gene-2.3-mRNA-1 8 KEGG: 00960+1.4.3.21;Reactome: R-HSA-211945;KEGG: 00950+1.4.3.21;KEGG: 00410+1.4.3.21;KEGG: 00360+1.4.3.21;KEGG: 00260+1.4.3.21;KEGG: 00350+1.4.3.21;MetaCyc: PWY-5751 "Tropane, piperidine and pyridine alkaloid biosynthesis";"Phase I - Functionalization of compounds";"Isoquinoline alkaloid biosynthesis";"beta-Alanine metabolism";"Phenylalanine metabolism";"Glycine, serine and threonine metabolism";"Tyrosine metabolism";"Phenylethanol biosynthesis" augustus-scaffold3262size10870-processed-gene-0.1-mRNA-1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" maker-scaffold6486size2679-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" maker-scaffold312size267838-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold273size264890-augustus-gene-1.3-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" augustus-scaffold1021size32086-processed-gene-0.0-mRNA-1 13 Reactome: R-HSA-6790901;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-6791226;Reactome: R-HSA-69166;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5685942 "rRNA modification in the nucleus and cytosol";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Major pathway of rRNA processing in the nucleolus and cytosol";"Removal of the Flap Intermediate";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)" maker-scaffold126size469926-augustus-gene-3.4-mRNA-1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" maker-scaffold644size65872-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation";"Complex I biogenesis";"Respiratory electron transport" maker-scaffold2741size8320-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" maker-scaffold8size1945031-augustus-gene-1.2-mRNA-1 5 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate" maker-scaffold158size418592-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" maker-scaffold1118size28084-augustus-gene-0.1-mRNA-1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" maker-scaffold138size440403-augustus-gene-3.17-mRNA-1 13 MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916 "Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation" maker-scaffold1439size19542-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold45size832949-augustus-gene-4.27-mRNA-1 7 Reactome: R-HSA-2672351;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855183 "Stimuli-sensing channels";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol" maker-scaffold1615size16835-augustus-gene-0.2-mRNA-1 27 Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-191859 "Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"snRNP Assembly" maker-scaffold173size392796-augustus-gene-2.1-mRNA-1 4 Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50 "Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism" maker-scaffold47size1319914-augustus-gene-2.0-mRNA-1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" maker-scaffold170size397864-augustus-gene-2.4-mRNA-1 17 Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" maker-scaffold26size1667613-augustus-gene-5.3-mRNA-1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes" maker-scaffold746size51651-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold4size1754260-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold8size1945031-augustus-gene-6.0-mRNA-1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325 "SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis" maker-scaffold5size1727520-augustus-gene-15.3-mRNA-1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" maker-scaffold15size1261043-augustus-gene-5.2-mRNA-1 11 Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-212436;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-383280;Reactome: R-HSA-2151201 "RORA activates gene expression";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway";"Circadian Clock";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis" augustus-scaffold2037size12315-processed-gene-0.0-mRNA-1 14 KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-611105;Reactome: R-HSA-71403;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238 "Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucose biosynthesis I";"Glycerolipid metabolism";"Stachyose degradation";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Glycogen synthesis";"Galactose metabolism";"Sucrose biosynthesis II" maker-scaffold145size712617-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" maker-scaffold14size1670589-augustus-gene-5.2-mRNA-1 4 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" maker-scaffold620size71785-augustus-gene-0.2-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold2691size8513-augustus-gene-0.0-mRNA-1 58 Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5689901;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783 "Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Metalloprotease DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome" maker-scaffold55size783029-augustus-gene-1.4-mRNA-1 27 Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-159231 "Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of RNA binding proteins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript" maker-scaffold70size694644-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold995size33530-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" maker-scaffold345size208198-augustus-gene-1.0-mRNA-1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" maker-scaffold266size269306-augustus-gene-1.6-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold27size1200182-augustus-gene-7.1-mRNA-1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Neutrophil degranulation" maker-scaffold4size1754260-augustus-gene-13.6-mRNA-1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" maker-scaffold6size1916839-augustus-gene-3.1-mRNA-1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold583size81945-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold4550size16156-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold92size586643-augustus-gene-4.2-mRNA-1 56 Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091 "G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells" maker-scaffold89size602897-augustus-gene-0.3-mRNA-1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis" maker-scaffold145size712617-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" maker-scaffold4size1754260-augustus-gene-12.0-mRNA-1 14 Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692 "Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity" maker-scaffold170size397864-augustus-gene-2.2-mRNA-1 16 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex" maker-scaffold1642size16517-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold24size1136029-augustus-gene-3.6-mRNA-1 4 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" maker-scaffold1656size16301-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" maker-scaffold36size1013817-augustus-gene-8.0-mRNA-1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" maker-scaffold122size477764-augustus-gene-3.4-mRNA-1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" maker-scaffold87size608750-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" maker-scaffold122size477764-augustus-gene-2.1-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold4size1754260-augustus-gene-2.3-mRNA-1 9 Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" maker-scaffold22size1201825-augustus-gene-1.4-mRNA-1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" maker-scaffold840size43361-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-6782315;KEGG: 00565+3.1.1.47 "tRNA modification in the nucleus and cytosol";"Ether lipid metabolism" maker-scaffold115size502811-augustus-gene-0.0-mRNA-1 15 Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884 "Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX" maker-scaffold66size1200099-augustus-gene-6.1-mRNA-1 11 MetaCyc: PWY-6545;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7187;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism" maker-scaffold11size1424826-augustus-gene-9.1-mRNA-1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" maker-scaffold3980size13534-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" maker-scaffold110size515606-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" maker-scaffold71size686415-augustus-gene-1.3-mRNA-1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" maker-scaffold2size2657229-augustus-gene-21.2-mRNA-1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" maker-scaffold94size584535-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold319size221683-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" augustus-scaffold1520size18178-processed-gene-0.1-mRNA-1 31 Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-2644606;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-4615885;Reactome: R-HSA-5610780;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2644607;Reactome: R-HSA-187577;Reactome: R-HSA-400253;Reactome: R-HSA-9604323;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-5607761;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1170546 "Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"SUMOylation of DNA replication proteins";"Degradation of GLI1 by the proteasome";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Circadian Clock";"Negative regulation of NOTCH4 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"Dectin-1 mediated noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Prolactin receptor signaling" maker-scaffold2636size14662-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold31size1053862-augustus-gene-6.0-mRNA-1 8 Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;Reactome: R-HSA-1989781 "Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression" maker-scaffold386size172899-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" maker-scaffold2975size7564-augustus-gene-0.2-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold4004size4238-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" maker-scaffold2size2657229-augustus-gene-17.6-mRNA-1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" maker-scaffold165size402902-augustus-gene-1.4-mRNA-1 10 Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-382556;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-381042;Reactome: R-HSA-72731;Reactome: R-HSA-9648895 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"PERK regulates gene expression";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency" maker-scaffold3389size12254-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold77size662763-augustus-gene-5.1-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold188size365332-augustus-gene-2.4-mRNA-1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" maker-scaffold14size1670589-augustus-gene-3.2-mRNA-1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" maker-scaffold50size801739-augustus-gene-6.3-mRNA-1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" maker-scaffold200size345481-augustus-gene-2.15-mRNA-1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" maker-scaffold294size242463-augustus-gene-1.0-mRNA-1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway" maker-scaffold26size1667613-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-1296061 "HCN channels" maker-scaffold182size404474-augustus-gene-2.0-mRNA-1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" maker-scaffold39size909063-augustus-gene-4.2-mRNA-1 1 Reactome: R-HSA-186797 "Signaling by PDGF" maker-scaffold14size1670589-augustus-gene-15.0-mRNA-1 3 Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle" maker-scaffold223size319359-augustus-gene-2.7-mRNA-1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold237size302539-augustus-gene-2.14-mRNA-1 5 MetaCyc: PWY-6614;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3 "Tetrahydrofolate biosynthesis";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate biosynthesis";"One carbon pool by folate" maker-scaffold136size447168-augustus-gene-3.8-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold65size703589-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" augustus-scaffold2198size10965-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold180size376838-augustus-gene-1.6-mRNA-1 4 Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;MetaCyc: PWY-7250 "Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis" maker-scaffold1882size13828-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" maker-scaffold4size1754260-augustus-gene-3.1-mRNA-1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" maker-scaffold8size1945031-augustus-gene-7.0-mRNA-1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" maker-scaffold299size238480-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold75size670735-augustus-gene-4.0-mRNA-1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" maker-scaffold2495size17002-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold169size953240-augustus-gene-5.18-mRNA-1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" maker-scaffold2252size10539-augustus-gene-0.0-mRNA-1 18 MetaCyc: PWY-7224;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7176;MetaCyc: PWY-7187 "Purine deoxyribonucleosides salvage";"Pyrimidine metabolism";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" maker-scaffold12size1412574-augustus-gene-5.6-mRNA-1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold53size789746-augustus-gene-2.0-mRNA-1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" maker-scaffold305size233158-augustus-gene-1.6-mRNA-1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" maker-scaffold3size2782310-augustus-gene-4.26-mRNA-1 16 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" maker-scaffold138size440403-augustus-gene-3.19-mRNA-1 6 MetaCyc: PWY-4261;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-6118 "Glycerol degradation I";"Synthesis of PA";"Glycerophospholipid metabolism";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle" maker-scaffold9size1444705-augustus-gene-4.8-mRNA-1 4 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16 "Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism" maker-scaffold1size2756217-augustus-gene-2.4-mRNA-1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" maker-scaffold247size292830-augustus-gene-1.5-mRNA-1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823 "Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex" maker-scaffold14size1670589-augustus-gene-15.11-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold9size1444705-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold402size240807-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold6size1916839-augustus-gene-6.3-mRNA-1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" maker-scaffold72size687670-augustus-gene-5.11-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold14size1670589-augustus-gene-13.3-mRNA-1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" maker-scaffold24size1136029-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold307size231700-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" maker-scaffold279size261100-augustus-gene-1.0-mRNA-1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" maker-scaffold192size359585-augustus-gene-2.16-mRNA-1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" maker-scaffold672size60097-augustus-gene-0.7-mRNA-1 6 MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5789 "3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Biotin transport and metabolism";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle" maker-scaffold4size1754260-augustus-gene-9.5-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold34size991984-augustus-gene-7.1-mRNA-1 2 MetaCyc: PWY-6938;Reactome: R-HSA-418594 "NADH repair";"G alpha (i) signalling events" maker-scaffold43size857109-augustus-gene-5.0-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold14size1670589-augustus-gene-3.3-mRNA-1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" maker-scaffold91size593915-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" augustus-scaffold6125size2778-processed-gene-0.0-mRNA-1 3 KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" maker-scaffold256size285501-augustus-gene-1.2-mRNA-1 2 MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" maker-scaffold170size397864-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold28size1079920-augustus-gene-9.12-mRNA-1 13 Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"EPHA-mediated growth cone collapse";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events" maker-scaffold30size1054049-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" maker-scaffold42size1661181-augustus-gene-11.0-mRNA-1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-2408557 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis" maker-scaffold185size368400-augustus-gene-2.10-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold38size924328-augustus-gene-2.0-mRNA-1 8 KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6791226 "PI3K-Akt signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold13size1375079-augustus-gene-4.21-mRNA-1 1 Reactome: R-HSA-74217 "Purine salvage" maker-scaffold183size369409-augustus-gene-2.6-mRNA-1 6 KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;Reactome: R-HSA-1268020 "Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import" maker-scaffold1size2756217-augustus-gene-4.23-mRNA-1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" maker-scaffold755size51166-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-71064 "Lysine catabolism" maker-scaffold11size1424826-augustus-gene-9.3-mRNA-1 27 Reactome: R-HSA-111367;Reactome: R-HSA-159227;Reactome: R-HSA-975957;Reactome: R-HSA-72203;Reactome: R-HSA-975956;Reactome: R-HSA-72165;Reactome: R-HSA-159231;Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-113418;Reactome: R-HSA-77595;Reactome: R-HSA-167200;Reactome: R-HSA-6803529;Reactome: R-HSA-191859;Reactome: R-HSA-72187;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-159236;Reactome: R-HSA-674695;Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "SLBP independent Processing of Histone Pre-mRNAs";"Transport of the SLBP independent Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Processing of Capped Intron-Containing Pre-mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the Early Elongation Complex";"Processing of Intronless Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"FGFR2 alternative splicing";"snRNP Assembly";"mRNA 3'-end processing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Pre-transcription Events";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" maker-scaffold185size368400-augustus-gene-0.0-mRNA-1 12 Reactome: R-HSA-75893;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-2894862 "TNF signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Growth hormone receptor signaling";"Signaling by EGFR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" augustus-scaffold1136size27262-processed-gene-0.1-mRNA-1 16 Reactome: R-HSA-1655829;Reactome: R-HSA-5632681;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-381033;KEGG: 00380+1.2.4.2;Reactome: R-HSA-8963889;KEGG: 00020+1.2.4.2;Reactome: R-HSA-5362798;Reactome: R-HSA-389661;Reactome: R-HSA-5632684;MetaCyc: PWY-5084;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-8874211;KEGG: 00310+1.2.4.2 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Ligand-receptor interactions";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"ATF6 (ATF6-alpha) activates chaperones";"Tryptophan metabolism";"Assembly of active LPL and LIPC lipase complexes";"Citrate cycle (TCA cycle)";"Release of Hh-Np from the secreting cell";"Glyoxylate metabolism and glycine degradation";"Hedgehog 'on' state";"2-oxoglutarate decarboxylation to succinyl-CoA";"Class B/2 (Secretin family receptors)";"Activation of SMO";"CREB3 factors activate genes";"Lysine degradation" maker-scaffold9size1444705-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" maker-scaffold1700size15819-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-901032 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"ER Quality Control Compartment (ERQC)" maker-scaffold1size2756217-augustus-gene-16.7-mRNA-1 1 Reactome: R-HSA-1632852 "Macroautophagy" maker-scaffold597size78930-augustus-gene-0.1-mRNA-1 11 Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-2173796 "RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" maker-scaffold555size113632-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-9609523;Reactome: R-HSA-6811438;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Intra-Golgi traffic";"Cargo concentration in the ER";"COPII-mediated vesicle transport" maker-scaffold429size142089-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" augustus-scaffold1840size14228-processed-gene-0.0-mRNA-1 16 Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-3214847;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5685942;Reactome: R-HSA-201722 "Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"HATs acetylate histones";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Homologous Recombination (HRR)";"Formation of the beta-catenin:TCF transactivating complex" maker-scaffold49size896674-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" maker-scaffold85size629767-augustus-gene-3.0-mRNA-1 5 Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211981 "Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Xenobiotics" maker-scaffold54size1273868-augustus-gene-11.11-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold16size1255579-augustus-gene-4.26-mRNA-1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" maker-scaffold6168size2763-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" maker-scaffold42size1661181-augustus-gene-15.0-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold18462size7691-augustus-gene-0.3-mRNA-1 5 Reactome: R-HSA-197264;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21 "Nicotinamide salvaging";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism" maker-scaffold2286size15097-augustus-gene-0.4-mRNA-1 22 MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7728;MetaCyc: PWY-7619;MetaCyc: PWY-7727;MetaCyc: PWY-7606;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7726;MetaCyc: PWY-5353;MetaCyc: PWY-6433;MetaCyc: PWY-7049;MetaCyc: PWY-8041;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-6958;MetaCyc: PWY-7592 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)" maker-scaffold32size1041436-augustus-gene-6.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold1041size31313-augustus-gene-0.1-mRNA-1 21 MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00254+6.4.1.2;Reactome: R-HSA-6790901;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;Reactome: R-HSA-8949613;MetaCyc: PWY-5744;MetaCyc: PWY-6679;Reactome: R-HSA-6791226;Reactome: R-HSA-163765;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163210;MetaCyc: PWY-5743;Reactome: R-HSA-2426168 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Aflatoxin biosynthesis";"rRNA modification in the nucleus and cytosol";"Pyruvate metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cristae formation";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"ChREBP activates metabolic gene expression";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Fatty acid biosynthesis";"Formation of ATP by chemiosmotic coupling";"3-hydroxypropanoate cycle";"Activation of gene expression by SREBF (SREBP)" maker-scaffold1359size20962-augustus-gene-0.1-mRNA-1 8 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" maker-scaffold1size2756217-augustus-gene-16.3-mRNA-1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" maker-scaffold47size1319914-augustus-gene-6.0-mRNA-1 11 Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163359 "G alpha (i) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Purine metabolism";"PKA activation";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation" maker-scaffold362size197294-augustus-gene-0.0-mRNA-1 7 KEGG: 00400+4.2.1.10;KEGG: 00400+4.2.3.4;MetaCyc: PWY-6416;KEGG: 00400+1.1.1.25;MetaCyc: PWY-6164;MetaCyc: PWY-6707;MetaCyc: PWY-6163 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Quinate degradation II";"Phenylalanine, tyrosine and tryptophan biosynthesis";"3-dehydroquinate biosynthesis I";"Gallate biosynthesis";"Chorismate biosynthesis from 3-dehydroquinate" maker-scaffold574size83631-augustus-gene-0.3-mRNA-1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" maker-scaffold103size553987-augustus-gene-1.1-mRNA-1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" maker-scaffold64size713537-augustus-gene-4.4-mRNA-1 1 Reactome: R-HSA-201451 "Signaling by BMP" augustus-scaffold1210size24171-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold77size662763-augustus-gene-4.0-mRNA-1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" maker-scaffold335size212668-augustus-gene-1.9-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" augustus-scaffold915size37765-processed-gene-0.0-mRNA-1 22 MetaCyc: PWY-7385;MetaCyc: PWY-5659;MetaCyc: PWY-6981;Reactome: R-HSA-5628897;MetaCyc: PWY-6142;MetaCyc: PWY-5054;MetaCyc: PWY-621;Reactome: R-HSA-70171;MetaCyc: PWY-6992;Reactome: R-HSA-70263;MetaCyc: PWY-7238;KEGG: 00500+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-622;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-8013;KEGG: 00520+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-5384;MetaCyc: PWY-5514;Reactome: R-HSA-6798695 "1,3-propanediol biosynthesis (engineered)";"GDP-mannose biosynthesis";"Chitin biosynthesis";"TP53 Regulates Metabolic Genes";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"D-sorbitol biosynthesis I";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"1,5-anhydrofructose degradation";"Gluconeogenesis";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Pentose phosphate pathway";"Starch biosynthesis";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis III";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Sucrose degradation IV (sucrose phosphorylase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Neutrophil degranulation" maker-scaffold16size1255579-augustus-gene-5.4-mRNA-1 45 Reactome: R-HSA-3371497;Reactome: R-HSA-1482922;Reactome: R-HSA-5617833;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-1650814;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-983189;Reactome: R-HSA-437239;KEGG: 00330+1.14.11.2;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;Reactome: R-HSA-5663220;KEGG: 00565+3.1.1.4;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;MetaCyc: PWY-7894;MetaCyc: PWY-7417;Reactome: R-HSA-8852276;Reactome: R-HSA-190840;MetaCyc: PWY-8053;Reactome: R-HSA-2467813;Reactome: R-HSA-1482801 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Acyl chain remodelling of PI";"Cilium Assembly";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Collagen biosynthesis and modifying enzymes";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Kinesins";"Recycling pathway of L1";"Arginine and proline metabolism";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Arachidonic acid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"RHO GTPases Activate Formins";"Ether lipid metabolism";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"MHC class II antigen presentation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Plasmalogen degradation";"Linoleic acid metabolism";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Procollagen hydroxylation and glycosylation";"Phospholipid remodeling (phosphatidate, yeast)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Anandamide biosynthesis II";"Separation of Sister Chromatids";"Acyl chain remodelling of PS" maker-scaffold104size538128-augustus-gene-2.4-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold13size1375079-augustus-gene-4.5-mRNA-1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" maker-scaffold17size1249603-augustus-gene-11.26-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold4size1754260-augustus-gene-16.9-mRNA-1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" maker-scaffold19size1242042-augustus-gene-8.1-mRNA-1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" maker-scaffold25size1130848-augustus-gene-6.0-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold61size761052-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold277size261747-augustus-gene-1.8-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold5664size7950-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" maker-scaffold13size1375079-augustus-gene-4.17-mRNA-1 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway" maker-scaffold10size1426409-augustus-gene-5.4-mRNA-1 6 Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8939902 "Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity" maker-scaffold100size555673-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold84size638750-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" maker-scaffold176size389526-augustus-gene-0.0-mRNA-1 16 Reactome: R-HSA-437239;Reactome: R-HSA-164939;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665 "Recycling pathway of L1";"Nef mediated downregulation of CD28 cell surface expression";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Formation of annular gap junctions";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells" maker-scaffold974size34674-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" maker-scaffold6185size2758-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" maker-scaffold3size2782310-augustus-gene-1.0-mRNA-1 57 Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-68949 "SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Orc1 removal from chromatin" maker-scaffold6size1916839-augustus-gene-14.4-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold1026size31955-augustus-gene-0.0-mRNA-1 6 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-110320;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Translesion Synthesis by POLH";"Formation of tubulin folding intermediates by CCT/TriC" maker-scaffold36size1013817-augustus-gene-4.19-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" maker-scaffold284size253718-augustus-gene-1.10-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" augustus-scaffold919size37610-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" maker-scaffold18size2240851-augustus-gene-12.2-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold28size1079920-augustus-gene-6.0-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold12565size7651-augustus-gene-0.1-mRNA-1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-350562;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-180534 "Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Ub-specific processing proteases";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of ornithine decarboxylase (ODC)";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4" maker-scaffold148size437419-augustus-gene-3.2-mRNA-1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold21size1197050-augustus-gene-7.4-mRNA-1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" maker-scaffold16size1255579-augustus-gene-11.14-mRNA-1 3 Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989 "RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" maker-scaffold203size341691-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold210size338753-augustus-gene-2.9-mRNA-1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold14size1670589-augustus-gene-15.9-mRNA-1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" maker-scaffold1size2756217-augustus-gene-7.1-mRNA-1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" maker-scaffold234size306624-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" maker-scaffold326size219560-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" maker-scaffold77size662763-augustus-gene-4.2-mRNA-1 3 Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17 "Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" maker-scaffold103size553987-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold5503size2969-augustus-gene-0.1-mRNA-1 18 MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7220 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Pyrimidine metabolism";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II" maker-scaffold42size1661181-augustus-gene-10.2-mRNA-1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" maker-scaffold16size1255579-augustus-gene-5.0-mRNA-1 3 Reactome: R-HSA-5693607;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "Processing of DNA double-strand break ends";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" maker-scaffold1size2756217-augustus-gene-25.4-mRNA-1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold1042size31297-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold303size235620-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" maker-scaffold1799size14718-augustus-gene-0.2-mRNA-1 10 Reactome: R-HSA-2151201;MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6700;MetaCyc: PWY-6722;MetaCyc: PWY-4381 "Transcriptional activation of mitochondrial biogenesis";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Queuosine biosynthesis I (de novo)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" maker-scaffold138size440403-augustus-gene-3.9-mRNA-1 1 Reactome: R-HSA-71288 "Creatine metabolism" maker-scaffold28size1079920-augustus-gene-7.2-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold20size1234842-augustus-gene-4.8-mRNA-1 8 Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-68952 "Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex";"DNA replication initiation" maker-scaffold740size52443-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" maker-scaffold4926size20599-augustus-gene-0.2-mRNA-1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold49size896674-augustus-gene-6.5-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold87size608750-augustus-gene-4.2-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold23size1161859-augustus-gene-1.0-mRNA-1 2 KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" maker-scaffold670size60319-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5617833;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Cilium Assembly";"Complex I biogenesis";"Respiratory electron transport" maker-scaffold31size1053862-augustus-gene-1.5-mRNA-1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" maker-scaffold26size1667613-augustus-gene-12.3-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold37size976698-augustus-gene-1.6-mRNA-1 2 Reactome: R-HSA-139853;Reactome: R-HSA-418346 "Elevation of cytosolic Ca2+ levels";"Platelet homeostasis" maker-scaffold284size253718-augustus-gene-1.9-mRNA-1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" maker-scaffold12size1412574-augustus-gene-1.0-mRNA-1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" maker-scaffold5size1727520-augustus-gene-11.3-mRNA-1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" maker-scaffold59size767954-augustus-gene-3.13-mRNA-1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" maker-scaffold37size976698-augustus-gene-7.7-mRNA-1 11 KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675;MetaCyc: PWY-381;Reactome: R-HSA-8964539;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-6963;MetaCyc: PWY-6964 "Nitrogen metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)";"Nitrate reduction II (assimilatory)";"Glutamate and glutamine metabolism";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II" maker-scaffold37size976698-augustus-gene-3.10-mRNA-1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" maker-scaffold53size789746-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" augustus-scaffold5238size7257-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" maker-scaffold8613size7777-augustus-gene-0.0-mRNA-1 8 Reactome: R-HSA-77387;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" maker-scaffold145size712617-augustus-gene-6.13-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold42size1661181-augustus-gene-7.0-mRNA-1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold210size338753-augustus-gene-2.17-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold169size953240-augustus-gene-7.2-mRNA-1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" maker-scaffold254size288410-augustus-gene-1.21-mRNA-1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" maker-scaffold218size326752-augustus-gene-2.19-mRNA-1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" maker-scaffold42size1661181-augustus-gene-8.3-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold4740size3283-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" maker-scaffold292size244886-augustus-gene-1.2-mRNA-1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" maker-scaffold1541size17801-augustus-gene-0.0-mRNA-1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" maker-scaffold170size397864-augustus-gene-3.2-mRNA-1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-167044;Reactome: R-HSA-5673001 "VEGFA-VEGFR2 Pathway";"Signalling to RAS";"RAF/MAP kinase cascade" maker-scaffold126size469926-augustus-gene-3.3-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold8size1945031-augustus-gene-4.0-mRNA-1 16 Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897 "MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes" maker-scaffold133size449948-augustus-gene-3.4-mRNA-1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold157size419459-augustus-gene-3.14-mRNA-1 13 KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52 "Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation" maker-scaffold12size1412574-augustus-gene-5.4-mRNA-1 14 Reactome: R-HSA-380259;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436 "Loss of Nlp from mitotic centrosomes";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold92size586643-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold59size767954-augustus-gene-6.11-mRNA-1 12 Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9619483 "Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Macroautophagy";"Human papillomavirus infection";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Activation of AMPK downstream of NMDARs" maker-scaffold5size1727520-augustus-gene-5.6-mRNA-1 3 KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" maker-scaffold86size613819-augustus-gene-3.6-mRNA-1 5 MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)" maker-scaffold54size1273868-augustus-gene-8.7-mRNA-1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" maker-scaffold2size2657229-augustus-gene-25.21-mRNA-1 7 Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" maker-scaffold786size48394-augustus-gene-0.1-mRNA-1 12 Reactome: R-HSA-75893;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-982772;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-5362798;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-193692 "TNF signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Growth hormone receptor signaling";"Signaling by EGFR";"Nuclear signaling by ERBB4";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR" maker-scaffold90size602833-augustus-gene-1.0-mRNA-1 7 KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-201722;KEGG: 00073+2.3.1.20;Reactome: R-HSA-171319;Reactome: R-HSA-6798695 "Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Formation of the beta-catenin:TCF transactivating complex";"Cutin, suberine and wax biosynthesis";"Telomere Extension By Telomerase";"Neutrophil degranulation" maker-scaffold829size44253-augustus-gene-0.2-mRNA-1 57 Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610785 "CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Downstream TCR signaling";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome" maker-scaffold92size586643-augustus-gene-4.17-mRNA-1 10 MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-7344 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis" maker-scaffold102size543958-augustus-gene-1.2-mRNA-1 1 KEGG: 00500+3.2.1.39 "Starch and sucrose metabolism" maker-scaffold69size700346-augustus-gene-1.0-mRNA-1 4 Reactome: R-HSA-381753;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-420029 "Olfactory Signaling Pathway";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions" maker-scaffold938size36899-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" maker-scaffold106size612477-augustus-gene-4.0-mRNA-1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" maker-scaffold20size1234842-augustus-gene-1.0-mRNA-1 9 KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52 "Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis" augustus-scaffold5087size3105-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" maker-scaffold48size811354-augustus-gene-4.20-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold246size295413-augustus-gene-2.0-mRNA-1 10 MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5895;MetaCyc: PWY-5839;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5844 "Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-9 biosynthesis" maker-scaffold12size1412574-augustus-gene-13.7-mRNA-1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" maker-scaffold12size1412574-augustus-gene-13.11-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold110size515606-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" augustus-scaffold816size45572-processed-gene-0.1-mRNA-1 7 KEGG: 00380+1.13.11.6;Reactome: R-HSA-71240;Reactome: R-HSA-3371453;MetaCyc: PWY-6505;MetaCyc: PWY-5651;MetaCyc: PWY-5647;MetaCyc: PWY-6309 "Tryptophan metabolism";"Tryptophan catabolism";"Regulation of HSF1-mediated heat shock response";"L-tryptophan degradation XII (Geobacillus)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"2-nitrobenzoate degradation I";"L-tryptophan degradation XI (mammalian, via kynurenine)" maker-scaffold10size1426409-augustus-gene-5.2-mRNA-1 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" maker-scaffold11size1424826-augustus-gene-5.2-mRNA-1 7 Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1 "Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis" maker-scaffold273size264890-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" maker-scaffold227size314013-augustus-gene-2.8-mRNA-1 9 Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol" maker-scaffold1size2756217-augustus-gene-10.0-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold8size1945031-augustus-gene-4.21-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold925size37451-augustus-gene-0.0-mRNA-1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" maker-scaffold55size783029-augustus-gene-6.0-mRNA-1 3 Reactome: R-HSA-975577;Reactome: R-HSA-913709;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"O-linked glycosylation of mucins";"Keratan sulfate biosynthesis" maker-scaffold173size392796-augustus-gene-2.7-mRNA-1 9 Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-5744 "Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation" maker-scaffold157size419459-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold595size79064-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" maker-scaffold2size2657229-augustus-gene-1.5-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold22size1201825-augustus-gene-5.5-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold411size152019-augustus-gene-0.1-mRNA-1 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" maker-scaffold149size424757-augustus-gene-1.8-mRNA-1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838 "Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO" maker-scaffold1807size14749-augustus-gene-0.1-mRNA-1 6 KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-196780 "Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism" maker-scaffold414size149583-augustus-gene-0.3-mRNA-1 5 Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-9608290;Reactome: R-HSA-110357 "Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate processing";"Displacement of DNA glycosylase by APEX1" maker-scaffold327size222331-augustus-gene-1.3-mRNA-1 15 Reactome: R-HSA-75876;Reactome: R-HSA-6794361;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7724;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7036 "Synthesis of very long-chain fatty acyl-CoAs";"Neurexins and neuroligins";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II" maker-scaffold270size268122-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold8size1945031-augustus-gene-4.11-mRNA-1 13 Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit" maker-scaffold1288size22347-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" maker-scaffold19size1242042-augustus-gene-6.4-mRNA-1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" maker-scaffold3710size5121-augustus-gene-0.0-mRNA-1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" maker-scaffold365size193989-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" maker-scaffold1291size22217-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold16size1255579-augustus-gene-8.5-mRNA-1 6 MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-4381;MetaCyc: PWY-5743 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Glyoxylate assimilation";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle" maker-scaffold731size53447-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-3371453 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of HSF1-mediated heat shock response" maker-scaffold32size1041436-augustus-gene-8.0-mRNA-1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" maker-scaffold70size694644-augustus-gene-3.19-mRNA-1 2 KEGG: 00630+4.1.3.1;MetaCyc: PWY-6969 "Glyoxylate and dicarboxylate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" maker-scaffold4size1754260-augustus-gene-8.3-mRNA-1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" maker-scaffold282size258062-augustus-gene-1.7-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold288size250223-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold13size1375079-augustus-gene-8.1-mRNA-1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" maker-scaffold76size663279-augustus-gene-5.6-mRNA-1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-1912420 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi" maker-scaffold8size1945031-augustus-gene-12.1-mRNA-1 1 KEGG: 00908+1.5.99.12 "Zeatin biosynthesis" maker-scaffold22size1201825-augustus-gene-4.20-mRNA-1 7 KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483166;MetaCyc: PWY-7039;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485 "Ether lipid metabolism";"Choline biosynthesis III";"Synthesis of PA";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Synthesis of PG";"Role of phospholipids in phagocytosis" maker-scaffold301size236721-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-1300642 "Sperm Motility And Taxes" maker-scaffold39size909063-augustus-gene-8.1-mRNA-1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" maker-scaffold1109size28593-augustus-gene-0.1-mRNA-1 32 Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-176974;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-983189;Reactome: R-HSA-389960;Reactome: R-HSA-68962;Reactome: R-HSA-437239;Reactome: R-HSA-176187;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-389977;Reactome: R-HSA-5663220;Reactome: R-HSA-69052;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-380320 "Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Unwinding of DNA";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Kinesins";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of the pre-replicative complex";"Recycling pathway of L1";"Activation of ATR in response to replication stress";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Post-chaperonin tubulin folding pathway";"RHO GTPases Activate Formins";"Switching of origins to a post-replicative state";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes" maker-scaffold59size767954-augustus-gene-3.1-mRNA-1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" maker-scaffold18size2240851-augustus-gene-4.21-mRNA-1 4 Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300 "Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy";"SUMOylation of transcription cofactors" maker-scaffold190size360960-augustus-gene-2.0-mRNA-1 9 MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" maker-scaffold1098size28945-augustus-gene-0.3-mRNA-1 4 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" augustus-scaffold994size33532-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" augustus-scaffold2694size8505-processed-gene-0.0-mRNA-1 4 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-6782315;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"tRNA modification in the nucleus and cytosol";"Displacement of DNA glycosylase by APEX1" maker-scaffold238size302402-augustus-gene-2.4-mRNA-1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" maker-scaffold5704size2904-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold3189size6445-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" maker-scaffold36size1013817-augustus-gene-5.8-mRNA-1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" maker-scaffold58size769326-augustus-gene-3.4-mRNA-1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-192823 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation" maker-scaffold72size687670-augustus-gene-5.13-mRNA-1 1 Reactome: R-HSA-6783984 "Glycine degradation" augustus-scaffold868size41332-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" maker-scaffold171size496979-augustus-gene-3.2-mRNA-1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" maker-scaffold72size687670-augustus-gene-5.17-mRNA-1 8 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold46size820514-augustus-gene-7.1-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold1613size16857-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold289size296826-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" maker-scaffold10size1426409-augustus-gene-3.0-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold3size2782310-augustus-gene-4.8-mRNA-1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" maker-scaffold121size481755-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" maker-scaffold49size896674-augustus-gene-5.5-mRNA-1 16 Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" maker-scaffold14size1670589-augustus-gene-12.3-mRNA-1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Photosynthesis";"ATP biosynthesis";"Insulin receptor recycling" maker-scaffold1size2756217-augustus-gene-19.0-mRNA-1 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" maker-scaffold335size212668-augustus-gene-1.4-mRNA-1 30 Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-189085;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776 "RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"Digestion of dietary carbohydrate";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"mRNA Capping";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape" maker-scaffold4524size10009-augustus-gene-0.0-mRNA-1 7 Reactome: R-HSA-389960;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Formation of tubulin folding intermediates by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold71size686415-augustus-gene-1.4-mRNA-1 5 KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403 "Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling" maker-scaffold1877size13876-augustus-gene-0.1-mRNA-1 8 Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781 "Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression" maker-scaffold89size602897-augustus-gene-5.8-mRNA-1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" maker-scaffold24size1136029-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" maker-scaffold429size142089-augustus-gene-0.5-mRNA-1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" maker-scaffold2size2657229-augustus-gene-4.4-mRNA-1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" maker-scaffold1639size22994-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" maker-scaffold255size285696-augustus-gene-1.12-mRNA-1 8 Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-1989781 "Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression" maker-scaffold2495size17002-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold19size1242042-augustus-gene-11.7-mRNA-1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs" maker-scaffold75size670735-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold169size953240-augustus-gene-5.17-mRNA-1 1 Reactome: R-HSA-1632852 "Macroautophagy" maker-scaffold1size2756217-augustus-gene-4.4-mRNA-1 3 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" maker-scaffold89size602897-augustus-gene-1.9-mRNA-1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" maker-scaffold17size1249603-augustus-gene-11.14-mRNA-1 17 MetaCyc: PWY-7197;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotide phosphorylation";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" maker-scaffold1size2756217-augustus-gene-23.4-mRNA-1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" maker-scaffold53size789746-augustus-gene-7.1-mRNA-1 11 Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-7456;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8 "Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"Beta-(1,4)-mannan degradation";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism" maker-scaffold31size1053862-augustus-gene-2.1-mRNA-1 7 Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210 "Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" maker-scaffold70size694644-augustus-gene-5.9-mRNA-1 6 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" augustus-scaffold905size38638-processed-gene-0.1-mRNA-1 13 Reactome: R-HSA-77387;Reactome: R-HSA-9636467;MetaCyc: PWY-7536;MetaCyc: PWY-5189;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;KEGG: 00860+2.3.1.37;Reactome: R-HSA-917977;KEGG: 00260+2.3.1.37;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-189451 "Insulin receptor recycling";"Blockage of phagosome acidification";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Porphyrin and chlorophyll metabolism";"Transferrin endocytosis and recycling";"Glycine, serine and threonine metabolism";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Heme biosynthesis" maker-scaffold17size1249603-augustus-gene-10.6-mRNA-1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" maker-scaffold673size59979-augustus-gene-0.2-mRNA-1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" maker-scaffold19size1242042-augustus-gene-3.7-mRNA-1 9 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" maker-scaffold71size686415-augustus-gene-3.1-mRNA-1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" maker-scaffold266size269306-augustus-gene-1.12-mRNA-1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" maker-scaffold248size292329-augustus-gene-1.7-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold14size1670589-augustus-gene-10.6-mRNA-1 4 KEGG: 00340+3.5.2.7;MetaCyc: PWY-5030;MetaCyc: PWY-5028;Reactome: R-HSA-70921 "Histidine metabolism";"L-histidine degradation III";"L-histidine degradation II";"Histidine catabolism" maker-scaffold20size1234842-augustus-gene-4.1-mRNA-1 29 Reactome: R-HSA-912446;Reactome: R-HSA-6803207;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-69541;Reactome: R-HSA-349425;Reactome: R-HSA-6804760;Reactome: R-HSA-6803204;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-6804757;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-69473 "Meiotic recombination";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Stabilization of p53";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Activity through Methylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"HDR through Single Strand Annealing (SSA)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"Regulation of TP53 Degradation";"Human cytomegalovirus infection";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint" maker-scaffold11size1424826-augustus-gene-6.4-mRNA-1 12 Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-5250924;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" augustus-scaffold678size59324-processed-gene-0.0-mRNA-1 17 KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5844;Reactome: R-HSA-70688;MetaCyc: PWY-5849;MetaCyc: PWY-5895;MetaCyc: PWY-7432;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;MetaCyc: PWY-5890;Reactome: R-HSA-389661;Reactome: R-HSA-2142789;KEGG: 00400+4.2.1.51;KEGG: 00250+1.2.1.88;MetaCyc: PWY-5892;MetaCyc: PWY-5891;MetaCyc: PWY-5839 "Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Proline catabolism";"Menaquinol-6 biosynthesis";"Menaquinol-13 biosynthesis";"L-phenylalanine biosynthesis III (cytosolic, plants)";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Menaquinol-10 biosynthesis";"Glyoxylate metabolism and glycine degradation";"Ubiquinol biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Menaquinol-12 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis" maker-scaffold474size121996-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" maker-scaffold17size1249603-augustus-gene-9.2-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold492size112218-augustus-gene-0.1-mRNA-1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" maker-scaffold14size1670589-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" maker-scaffold88size603654-augustus-gene-5.1-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold92size586643-augustus-gene-3.0-mRNA-1 17 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" maker-scaffold180size376838-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" maker-scaffold1size2756217-augustus-gene-9.4-mRNA-1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" maker-scaffold84size638750-augustus-gene-5.1-mRNA-1 3 Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2" maker-scaffold14size1670589-augustus-gene-5.3-mRNA-1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling" maker-scaffold48size811354-augustus-gene-4.6-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold161size412613-augustus-gene-3.13-mRNA-1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" maker-scaffold2363size9957-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-2672351;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451;MetaCyc: PWY-7856 "Stimuli-sensing channels";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Heme a biosynthesis" maker-scaffold37size976698-augustus-gene-4.0-mRNA-1 8 Reactome: R-HSA-983168;Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-6799198;MetaCyc: PWY-7511;Reactome: R-HSA-532668;Reactome: R-HSA-8957275 "Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Complex I biogenesis";"Protein ubiquitination";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation" maker-scaffold54size1273868-augustus-gene-10.0-mRNA-1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" maker-scaffold22size1201825-augustus-gene-4.15-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold173size392796-augustus-gene-2.12-mRNA-1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" maker-scaffold76size663279-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold158size418592-augustus-gene-1.5-mRNA-1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" maker-scaffold1size2756217-augustus-gene-14.7-mRNA-1 16 Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174184 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" maker-scaffold65size703589-augustus-gene-5.3-mRNA-1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" maker-scaffold14size1670589-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" maker-scaffold25size1130848-augustus-gene-6.7-mRNA-1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" maker-scaffold4192size3832-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold205size344292-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" maker-scaffold2441size9645-augustus-gene-0.0-mRNA-1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state" maker-scaffold6size1916839-augustus-gene-11.5-mRNA-1 14 Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-112382 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex" maker-scaffold12size1412574-augustus-gene-5.1-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" maker-scaffold28size1079920-augustus-gene-9.15-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" augustus-scaffold561size87106-processed-gene-0.1-mRNA-1 3 Reactome: R-HSA-204174;Reactome: R-HSA-5362517;Reactome: R-HSA-70895 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Branched-chain amino acid catabolism" maker-scaffold4size1754260-augustus-gene-8.2-mRNA-1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" maker-scaffold1size2756217-augustus-gene-4.6-mRNA-1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607761 "Neddylation";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling" maker-scaffold34size991984-augustus-gene-9.2-mRNA-1 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" maker-scaffold70size694644-augustus-gene-5.7-mRNA-1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" maker-scaffold14size1670589-augustus-gene-15.1-mRNA-1 6 MetaCyc: PWY-7765;Reactome: R-HSA-71240;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-6309;MetaCyc: PWY-5651 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde" maker-scaffold158size418592-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" maker-scaffold10size1426409-augustus-gene-2.10-mRNA-1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" maker-scaffold55246size7190-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" maker-scaffold1size2756217-augustus-gene-14.5-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold45size832949-augustus-gene-3.4-mRNA-1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-69017 "CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6" maker-scaffold7size1668642-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold534size95417-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" maker-scaffold940size36807-augustus-gene-0.0-mRNA-1 8 KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5084;KEGG: 04660+3.1.3.16;KEGG: 00380+1.2.4.2;KEGG: 04658+3.1.3.16;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"2-oxoglutarate decarboxylation to succinyl-CoA";"T cell receptor signaling pathway";"Tryptophan metabolism";"Th1 and Th2 cell differentiation";"Lysine degradation" augustus-scaffold1052size30862-processed-gene-0.2-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold697size57287-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold802size46780-augustus-gene-0.2-mRNA-1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" maker-scaffold42size1661181-augustus-gene-1.1-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" maker-scaffold164size409319-augustus-gene-1.2-mRNA-1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418555 "Purine metabolism";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (s) signalling events" maker-scaffold49size896674-augustus-gene-3.4-mRNA-1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" maker-scaffold3size2782310-augustus-gene-4.25-mRNA-1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" maker-scaffold203size341691-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" maker-scaffold48size811354-augustus-gene-4.16-mRNA-1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" maker-scaffold10size1426409-augustus-gene-6.2-mRNA-1 5 Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221 "RAF activation";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway" maker-scaffold56size1152634-augustus-gene-6.0-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold260size277064-augustus-gene-1.3-mRNA-1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" maker-scaffold12size1412574-augustus-gene-9.3-mRNA-1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" maker-scaffold191size643645-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold120size483217-augustus-gene-3.9-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" augustus-scaffold651size64199-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" maker-scaffold572size84276-augustus-gene-0.1-mRNA-1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69166 "Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate" maker-scaffold36size1013817-augustus-gene-4.3-mRNA-1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-171007 "mTOR signaling pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"p38MAPK events" maker-scaffold50728size7056-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" maker-scaffold173size392796-augustus-gene-2.15-mRNA-1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" maker-scaffold823size44993-augustus-gene-0.1-mRNA-1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-5578749 "ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs" maker-scaffold257size284128-augustus-gene-1.1-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold75size670735-augustus-gene-5.3-mRNA-1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" maker-scaffold256size285501-augustus-gene-1.9-mRNA-1 6 Reactome: R-HSA-8862803;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;MetaCyc: PWY-6854 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Ethylene biosynthesis III (microbes)" augustus-scaffold8715size1280-processed-gene-0.1-mRNA-1 13 Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" maker-scaffold14size1670589-augustus-gene-11.0-mRNA-1 11 Reactome: R-HSA-6782135;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5685942 "Dual incision in TC-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)" maker-scaffold1size2756217-augustus-gene-12.1-mRNA-1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription" maker-scaffold155size419694-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold34size991984-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold226size315315-augustus-gene-2.0-mRNA-1 7 MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;MetaCyc: PWY-7039;Reactome: R-HSA-1855204 "2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol" maker-scaffold1size2756217-augustus-gene-0.3-mRNA-1 10 Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807 "HS-GAG degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"Other glycan degradation";"Neutrophil degranulation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)" maker-scaffold22size1201825-augustus-gene-5.3-mRNA-1 3 Reactome: R-HSA-212676;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736 "Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors" maker-scaffold6size1916839-augustus-gene-13.3-mRNA-1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" maker-scaffold110size515606-augustus-gene-3.23-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold6429size2692-augustus-gene-0.0-mRNA-1 6 Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-5689880;Reactome: R-HSA-6796648 "Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Ub-specific processing proteases";"TP53 Regulates Transcription of DNA Repair Genes" maker-scaffold409size152889-augustus-gene-0.2-mRNA-1 4 KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-8856828 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Clathrin-mediated endocytosis" maker-scaffold76size663279-augustus-gene-4.1-mRNA-1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" maker-scaffold192size359585-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" maker-scaffold2size2657229-augustus-gene-14.4-mRNA-1 6 Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" maker-scaffold364size352455-augustus-gene-2.10-mRNA-1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" maker-scaffold439size137304-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" maker-scaffold775size50094-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" augustus-scaffold5456size2985-processed-gene-0.0-mRNA-1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" maker-scaffold134size449309-augustus-gene-0.0-mRNA-1 12 Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096 "NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" maker-scaffold2334size14014-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold691size89654-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" maker-scaffold762size53541-augustus-gene-0.0-mRNA-1 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6798695 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Neutrophil degranulation" maker-scaffold126size469926-augustus-gene-3.2-mRNA-1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold21size1197050-augustus-gene-2.1-mRNA-1 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" maker-scaffold129size456722-augustus-gene-3.9-mRNA-1 5 Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold9size1444705-augustus-gene-3.0-mRNA-1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"T cell receptor signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold169size953240-augustus-gene-8.7-mRNA-1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" maker-scaffold54size1273868-augustus-gene-3.0-mRNA-1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" maker-scaffold238size302402-augustus-gene-2.6-mRNA-1 3 Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-429947 "ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Deadenylation of mRNA" maker-scaffold3size2782310-augustus-gene-4.12-mRNA-1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" maker-scaffold560size87469-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" maker-scaffold256size285501-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold5138size9877-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" augustus-scaffold2927size14741-processed-gene-0.1-mRNA-1 58 Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689901;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5658442 "Downstream TCR signaling";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Metalloprotease DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Neutrophil degranulation";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs" maker-scaffold31size1053862-augustus-gene-5.0-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold8size1945031-augustus-gene-18.0-mRNA-1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" maker-scaffold417size148004-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" maker-scaffold98size575737-augustus-gene-2.0-mRNA-1 7 Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505 "Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" maker-scaffold47size1319914-augustus-gene-8.2-mRNA-1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" maker-scaffold28size1079920-augustus-gene-7.0-mRNA-1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-6782315;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"tRNA modification in the nucleus and cytosol";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" maker-scaffold215size330995-augustus-gene-2.1-mRNA-1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" maker-scaffold80size1421260-augustus-gene-6.2-mRNA-1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-382556;Reactome: R-HSA-5678771 "PPARA activates gene expression";"ABC-family proteins mediated transport";"Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1" maker-scaffold21size1197050-augustus-gene-6.0-mRNA-1 56 Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276 "Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint" maker-scaffold22size1201825-augustus-gene-9.4-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold18size2240851-augustus-gene-11.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold200size345481-augustus-gene-2.21-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold256size285501-augustus-gene-1.8-mRNA-1 7 MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine biosynthesis" maker-scaffold192size359585-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" maker-scaffold7206size2004-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold89size602897-augustus-gene-3.0-mRNA-1 9 MetaCyc: PWY-6147;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-6703 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Preq0 biosynthesis" maker-scaffold5size1727520-augustus-gene-11.1-mRNA-1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" maker-scaffold691size89654-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" maker-scaffold411size152019-augustus-gene-0.8-mRNA-1 2 MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4 "Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism" maker-scaffold22size1201825-augustus-gene-5.1-mRNA-1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" maker-scaffold149size424757-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" maker-scaffold78size655360-augustus-gene-5.11-mRNA-1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)" maker-scaffold337size211899-augustus-gene-1.3-mRNA-1 20 Reactome: R-HSA-166208;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1 "mTORC1-mediated signalling";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Thermogenesis";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Human papillomavirus infection";"Macroautophagy";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTOR signalling";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Relaxin signaling pathway" maker-scaffold173size392796-augustus-gene-2.0-mRNA-1 5 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" maker-scaffold21size1197050-augustus-gene-8.2-mRNA-1 40 Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-77075;Reactome: R-HSA-72086;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-5578749;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-167238 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"HIV Transcription Initiation";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation" maker-scaffold49size896674-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold13size1375079-augustus-gene-4.25-mRNA-1 11 KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"p38MAPK events";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold27size1200182-augustus-gene-0.0-mRNA-1 1 MetaCyc: PWY-5901 "2,3-dihydroxybenzoate biosynthesis" maker-scaffold8size1945031-augustus-gene-7.1-mRNA-1 3 Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-194840 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Rho GTPase cycle" maker-scaffold235size305606-augustus-gene-1.8-mRNA-1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling" maker-scaffold17size1249603-augustus-gene-11.23-mRNA-1 3 Reactome: R-HSA-2995383;Reactome: R-HSA-2980766;Reactome: R-HSA-4419969 "Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina" maker-scaffold25size1130848-augustus-gene-7.6-mRNA-1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" maker-scaffold2334size14014-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" maker-scaffold25size1130848-augustus-gene-6.13-mRNA-1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" maker-scaffold281size259073-augustus-gene-1.2-mRNA-1 8 KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171 "Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis" maker-scaffold1563size17409-augustus-gene-0.0-mRNA-1 11 Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" maker-scaffold93size585897-augustus-gene-4.11-mRNA-1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" maker-scaffold1138size27084-augustus-gene-0.3-mRNA-1 5 Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3 "Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism" maker-scaffold85size629767-augustus-gene-4.9-mRNA-1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" maker-scaffold136size447168-augustus-gene-3.11-mRNA-1 1 Reactome: R-HSA-611105 "Respiratory electron transport" maker-scaffold125size471011-augustus-gene-0.0-mRNA-1 20 Reactome: R-HSA-5628897;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-3371571;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-166208;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-8943724 "TP53 Regulates Metabolic Genes";"Human papillomavirus infection";"Amino acids regulate mTORC1";"Macroautophagy";"PIP3 activates AKT signaling";"HSF1-dependent transactivation";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Human cytomegalovirus infection";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signalling";"Regulation of PTEN gene transcription" maker-scaffold13size1375079-augustus-gene-5.2-mRNA-1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73772 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape" maker-scaffold11size1424826-augustus-gene-4.3-mRNA-1 7 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-71403 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Lysine catabolism";"Citric acid cycle (TCA cycle)" maker-scaffold754size51190-augustus-gene-0.0-mRNA-1 32 Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-6782210;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;KEGG: 05235+3.1.3.16;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781823 "RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Gap-filling DNA repair synthesis and ligation in TC-NER";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex" maker-scaffold493size110888-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" maker-scaffold470size124269-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-8949613 "Cristae formation" augustus-scaffold4475size3487-processed-gene-0.0-mRNA-1 20 Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942 "Dual incision in TC-NER";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)" maker-scaffold2486size20878-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold75size670735-augustus-gene-5.9-mRNA-1 5 Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-936964 "Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" maker-scaffold526size170922-augustus-gene-0.7-mRNA-1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" maker-scaffold349size205196-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold943size36453-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" maker-scaffold591size83560-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" maker-scaffold1size2756217-augustus-gene-1.2-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold12size1412574-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold266size269306-augustus-gene-1.16-mRNA-1 16 Reactome: R-HSA-5693607;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-3214847;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-5685942 "Processing of DNA double-strand break ends";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HATs acetylate histones";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Homologous Recombination (HRR)" maker-scaffold2472size15045-augustus-gene-0.2-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold265size290839-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" maker-scaffold11size1424826-augustus-gene-10.5-mRNA-1 13 Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52 "Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation" maker-scaffold76size663279-augustus-gene-4.26-mRNA-1 1 Reactome: R-HSA-73621 "Pyrimidine catabolism" maker-scaffold196size353214-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" maker-scaffold1747size15351-augustus-gene-0.1-mRNA-1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold270size268122-augustus-gene-1.2-mRNA-1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" maker-scaffold8972size7592-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold86size613819-augustus-gene-3.18-mRNA-1 2 MetaCyc: PWY-6163;KEGG: 00400+4.2.3.5 "Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis" maker-scaffold1070size29979-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" maker-scaffold43size857109-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" maker-scaffold2size2657229-augustus-gene-5.1-mRNA-1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" maker-scaffold9size1444705-augustus-gene-4.2-mRNA-1 3 Reactome: R-HSA-6782315;Reactome: R-HSA-110362;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"POLB-Dependent Long Patch Base Excision Repair";"tRNA modification in the mitochondrion" maker-scaffold189size362018-augustus-gene-2.4-mRNA-1 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" maker-scaffold2size2657229-augustus-gene-19.5-mRNA-1 20 Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210 "Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER" maker-scaffold155size419694-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold3004size14211-augustus-gene-0.0-mRNA-1 7 MetaCyc: PWY-6527;Reactome: R-HSA-6791226;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;Reactome: R-HSA-6790901 "Stachyose degradation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"rRNA modification in the nucleus and cytosol" maker-scaffold6788size13373-augustus-gene-0.2-mRNA-1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72702 "Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition" maker-scaffold1size2756217-augustus-gene-5.3-mRNA-1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" maker-scaffold34size991984-augustus-gene-6.2-mRNA-1 11 Reactome: R-HSA-189085;Reactome: R-HSA-76042;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-9018519;Reactome: R-HSA-167161 "Digestion of dietary carbohydrate";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Estrogen-dependent gene expression";"HIV Transcription Initiation" maker-scaffold5size1727520-augustus-gene-13.0-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold17size1249603-augustus-gene-1.0-mRNA-1 16 Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" maker-scaffold98size575737-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold43size857109-augustus-gene-4.17-mRNA-1 57 Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-532668;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323 "Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ER-Phagosome pathway";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling" maker-scaffold2size2657229-augustus-gene-2.0-mRNA-1 26 Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-381340;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-9617629;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508 "TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of white adipocyte differentiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"PPARA activates gene expression";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription" maker-scaffold863size41626-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold17size1249603-augustus-gene-11.32-mRNA-1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" maker-scaffold284size253718-augustus-gene-1.16-mRNA-1 7 MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828 "3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis" maker-scaffold25size1130848-augustus-gene-8.0-mRNA-1 9 KEGG: 00380+3.5.1.9;MetaCyc: PWY-7765;MetaCyc: PWY-6309;Reactome: R-HSA-2022377;MetaCyc: PWY-5651;MetaCyc: PWY-7733;MetaCyc: PWY-7717;KEGG: 00630+3.5.1.9;MetaCyc: PWY-7734 "Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Metabolism of Angiotensinogen to Angiotensins";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxyquinaldate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Glyoxylate and dicarboxylate metabolism";"Quinoxaline-2-carboxylate biosynthesis" maker-scaffold37size976698-augustus-gene-1.7-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold13size1375079-augustus-gene-12.4-mRNA-1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" maker-scaffold8size1945031-augustus-gene-13.8-mRNA-1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-5617472;Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841 "Regulation of PTEN gene transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"HCMV Early Events";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines" maker-scaffold157size419459-augustus-gene-3.8-mRNA-1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" maker-scaffold13size1375079-augustus-gene-3.4-mRNA-1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" maker-scaffold416size148305-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" maker-scaffold14size1670589-augustus-gene-11.14-mRNA-1 6 KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6922 "Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis" maker-scaffold9size1444705-augustus-gene-12.6-mRNA-1 5 Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination" augustus-scaffold4321size8830-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold8size1945031-augustus-gene-15.8-mRNA-1 24 Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 04926+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-5674400;Reactome: R-HSA-114604;Reactome: R-HSA-389357;Reactome: R-HSA-354192;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-1257604 "Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Relaxin signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Constitutive Signaling by AKT1 E17K in Cancer";"GPVI-mediated activation cascade";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"RSK activation";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Thermogenesis";"Human papillomavirus infection";"Activation of AKT2";"PIP3 activates AKT signaling" maker-scaffold26size1667613-augustus-gene-7.0-mRNA-1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs" maker-scaffold335size212668-augustus-gene-1.7-mRNA-1 11 Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6969;MetaCyc: PWY-7124;MetaCyc: PWY-6728 "Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"Methylaspartate cycle" maker-scaffold85size629767-augustus-gene-2.2-mRNA-1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" maker-scaffold587size81631-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" maker-scaffold24size1136029-augustus-gene-10.1-mRNA-1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" maker-scaffold980size34325-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold660size62680-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" maker-scaffold6size1916839-augustus-gene-3.3-mRNA-1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation" maker-scaffold42size1661181-augustus-gene-1.3-mRNA-1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" maker-scaffold1879size21166-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold18size2240851-augustus-gene-4.9-mRNA-1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" maker-scaffold120size483217-augustus-gene-3.1-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold92size586643-augustus-gene-4.21-mRNA-1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" maker-scaffold59size767954-augustus-gene-3.5-mRNA-1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" maker-scaffold193size358747-augustus-gene-1.5-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold424size145378-augustus-gene-0.4-mRNA-1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912 "Methylation";"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis" maker-scaffold18677size7346-augustus-gene-0.0-mRNA-1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" augustus-scaffold1895size13685-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" maker-scaffold643size65972-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" maker-scaffold320size221394-augustus-gene-1.4-mRNA-1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" maker-scaffold22size1201825-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" maker-scaffold508size104511-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold271size267669-augustus-gene-1.12-mRNA-1 5 Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold208size344337-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" maker-scaffold9size1444705-augustus-gene-10.0-mRNA-1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" augustus-scaffold13296size7402-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold55size783029-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" maker-scaffold3size2782310-augustus-gene-23.0-mRNA-1 12 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840 "Relaxin signaling pathway";"Human papillomavirus infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"G alpha (12/13) signalling events";"Thermogenesis";"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Rho GTPase cycle" maker-scaffold879size40199-augustus-gene-0.0-mRNA-1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" maker-scaffold2size2657229-augustus-gene-23.2-mRNA-1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" maker-scaffold4768size15329-augustus-gene-0.2-mRNA-1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-5981;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8053;MetaCyc: PWY-5667 "Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I" maker-scaffold593size79447-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold463size137807-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold65size703589-augustus-gene-3.2-mRNA-1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972 "Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK" maker-scaffold45size832949-augustus-gene-4.18-mRNA-1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" maker-scaffold2149size18944-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" maker-scaffold54size1273868-augustus-gene-9.1-mRNA-1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" augustus-scaffold776size49194-processed-gene-0.0-mRNA-1 16 Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" maker-scaffold29size1057726-augustus-gene-7.1-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold138size440403-augustus-gene-3.7-mRNA-1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" maker-scaffold144size431038-augustus-gene-3.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" augustus-scaffold971size34872-processed-gene-0.3-mRNA-1 7 Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-606279;Reactome: R-HSA-3214847;Reactome: R-HSA-171319;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"Deposition of new CENPA-containing nucleosomes at the centromere";"HATs acetylate histones";"Telomere Extension By Telomerase";"UCH proteinases" maker-scaffold5714size9297-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold18size2240851-augustus-gene-11.0-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold2771size8178-augustus-gene-0.1-mRNA-1 52 Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-5250924;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-167161;Reactome: R-HSA-76066;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-72203;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-73780;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-73980 "RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"B-WICH complex positively regulates rRNA expression";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Chain Elongation";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination" maker-scaffold82size640827-augustus-gene-3.0-mRNA-1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" augustus-scaffold695size57383-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" maker-scaffold17size1249603-augustus-gene-11.9-mRNA-1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-4570464 "tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins" maker-scaffold364size352455-augustus-gene-2.11-mRNA-1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" augustus-scaffold1657size16289-processed-gene-0.0-mRNA-1 4 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453 "Cristae formation";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response" maker-scaffold31size1053862-augustus-gene-9.2-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold8size1945031-augustus-gene-7.6-mRNA-1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" maker-scaffold2125size12078-augustus-gene-0.0-mRNA-1 10 Reactome: R-HSA-174362;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-6683 "Transport and synthesis of PAPS";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Sulfate activation for sulfonation";"Purine metabolism";"Sulfite oxidation III";"Monobactam biosynthesis";"Sulfur metabolism";"Selenocompound metabolism";"Assimilatory sulfate reduction III" augustus-scaffold1368size20775-processed-gene-0.0-mRNA-1 12 MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-380994;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-173599;Reactome: R-HSA-9633012;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-4085011;Reactome: R-HSA-8963693;KEGG: 00534+5.1.3.17 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"ATF4 activates genes in response to endoplasmic reticulum stress";"Neutrophil degranulation";"Sialic acid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Defective GNE causes sialuria, Nonaka myopathy and inclusion body myopathy 2";"Aspartate and asparagine metabolism";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" maker-scaffold85size629767-augustus-gene-1.5-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold11size1424826-augustus-gene-7.2-mRNA-1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" maker-scaffold3size2782310-augustus-gene-4.15-mRNA-1 6 MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" maker-scaffold76size663279-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" maker-scaffold13382size7358-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" maker-scaffold356size200549-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" maker-scaffold254size288410-augustus-gene-1.13-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold173size392796-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold353size206126-augustus-gene-1.3-mRNA-1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" maker-scaffold49size896674-augustus-gene-6.3-mRNA-1 15 Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-9603505;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-167243 "Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"NTRK3 as a dependence receptor";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery" maker-scaffold270size268122-augustus-gene-1.6-mRNA-1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion" maker-scaffold1870size13957-augustus-gene-0.0-mRNA-1 24 Reactome: R-HSA-71403;MetaCyc: PWY-5659;Reactome: R-HSA-69473;MetaCyc: PWY-882;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-446205;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;MetaCyc: PWY-3861;Reactome: R-HSA-5685942;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-6992;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-6787450;MetaCyc: PWY-7456;Reactome: R-HSA-611105;MetaCyc: PWY-7586 "Citric acid cycle (TCA cycle)";"GDP-mannose biosynthesis";"G2/M DNA damage checkpoint";"L-ascorbate biosynthesis I (L-galactose pathway)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Synthesis of GDP-mannose";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"Mannitol degradation II";"HDR through Homologous Recombination (HRR)";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Fructose and mannose metabolism";"1,5-anhydrofructose degradation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"tRNA modification in the mitochondrion";"Beta-(1,4)-mannan degradation";"Respiratory electron transport";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" maker-scaffold41size887692-augustus-gene-3.0-mRNA-1 8 MetaCyc: PWY-5751;KEGG: 00350+1.4.3.21;KEGG: 00260+1.4.3.21;KEGG: 00360+1.4.3.21;KEGG: 00410+1.4.3.21;KEGG: 00950+1.4.3.21;Reactome: R-HSA-211945;KEGG: 00960+1.4.3.21 "Phenylethanol biosynthesis";"Tyrosine metabolism";"Glycine, serine and threonine metabolism";"Phenylalanine metabolism";"beta-Alanine metabolism";"Isoquinoline alkaloid biosynthesis";"Phase I - Functionalization of compounds";"Tropane, piperidine and pyridine alkaloid biosynthesis" augustus-scaffold1802size14688-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold361size197669-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold26size1667613-augustus-gene-4.0-mRNA-1 57 Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5610785;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768 "Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"GLI3 is processed to GLI3R by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Hedgehog 'on' state";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" maker-scaffold31size1053862-augustus-gene-6.6-mRNA-1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism" maker-scaffold11size1424826-augustus-gene-7.9-mRNA-1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" maker-scaffold8size1945031-augustus-gene-16.4-mRNA-1 7 Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-1632852 "TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"Macroautophagy" maker-scaffold42size1661181-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold78size655360-augustus-gene-5.10-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold31size1053862-augustus-gene-6.2-mRNA-1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" maker-scaffold386size172899-augustus-gene-0.2-mRNA-1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" maker-scaffold1460size19189-augustus-gene-0.0-mRNA-1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" maker-scaffold2895size8451-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" maker-scaffold34size991984-augustus-gene-4.2-mRNA-1 6 Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12 "Galactose catabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" maker-scaffold33size1007119-augustus-gene-4.2-mRNA-1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" maker-scaffold24229size7496-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" maker-scaffold470size124269-augustus-gene-0.12-mRNA-1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" maker-scaffold244size296644-augustus-gene-1.0-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold185size368400-augustus-gene-1.0-mRNA-1 9 Reactome: R-HSA-2871809;Reactome: R-HSA-5218920;Reactome: R-HSA-2871796;Reactome: R-HSA-114604;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "FCERI mediated Ca+2 mobilization";"VEGFR2 mediated vascular permeability";"FCERI mediated MAPK activation";"GPVI-mediated activation cascade";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" maker-scaffold1size2756217-augustus-gene-21.1-mRNA-1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" maker-scaffold1711size15735-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-5358493 "WNT ligand biogenesis and trafficking";"Synthesis of diphthamide-EEF2" maker-scaffold48size811354-augustus-gene-7.4-mRNA-1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" maker-scaffold2276size15003-augustus-gene-0.3-mRNA-1 7 MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis" maker-scaffold1size2756217-augustus-gene-20.5-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold271size267669-augustus-gene-1.2-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold574size83631-augustus-gene-0.7-mRNA-1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" maker-scaffold157size419459-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold3071size7115-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" maker-scaffold45size832949-augustus-gene-4.17-mRNA-1 17 Reactome: R-HSA-9645460;Reactome: R-HSA-4086398;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-975163;Reactome: R-HSA-5689880;Reactome: R-HSA-450302;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-450321;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-1169091 "Alpha-protein kinase 1 signaling pathway";"Ca2+ pathway";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Activation of NF-kappaB in B cells" maker-scaffold266size269306-augustus-gene-1.14-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" maker-scaffold65size703589-augustus-gene-1.2-mRNA-1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" maker-scaffold342size295439-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" maker-scaffold542size93235-augustus-gene-0.3-mRNA-1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" maker-scaffold439size137304-augustus-gene-0.3-mRNA-1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" maker-scaffold5size1727520-augustus-gene-16.14-mRNA-1 2 Reactome: R-HSA-111469;Reactome: R-HSA-111457 "SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria" maker-scaffold241size304314-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-189085 "ABC transporters in lipid homeostasis";"Digestion of dietary carbohydrate" maker-scaffold171size496979-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" maker-scaffold5size1727520-augustus-gene-13.3-mRNA-1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" maker-scaffold429size142089-augustus-gene-0.10-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold153size420471-augustus-gene-3.1-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold308size231414-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold413size150002-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" maker-scaffold16size1255579-augustus-gene-8.7-mRNA-1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" maker-scaffold489size113917-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" maker-scaffold18size2240851-augustus-gene-16.4-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold5218size3054-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold86size613819-augustus-gene-3.19-mRNA-1 5 Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-196741 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Cobalamin (Cbl, vitamin B12) transport and metabolism" maker-scaffold522size99678-augustus-gene-0.6-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold1size2756217-augustus-gene-11.8-mRNA-1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" maker-scaffold1size2756217-augustus-gene-13.5-mRNA-1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" maker-scaffold34size991984-augustus-gene-8.2-mRNA-1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" maker-scaffold181size378167-augustus-gene-2.1-mRNA-1 2 Reactome: R-HSA-139853;Reactome: R-HSA-418346 "Elevation of cytosolic Ca2+ levels";"Platelet homeostasis" maker-scaffold313size227280-augustus-gene-1.4-mRNA-1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" maker-scaffold417size148004-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" maker-scaffold169size953240-augustus-gene-8.16-mRNA-1 3 Reactome: R-HSA-196741;Reactome: R-HSA-1632852;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Macroautophagy";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" maker-scaffold22size1201825-augustus-gene-0.1-mRNA-1 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-983712 "Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Ion channel transport" maker-scaffold16size1255579-augustus-gene-7.0-mRNA-1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" maker-scaffold1size2756217-augustus-gene-6.8-mRNA-1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" maker-scaffold72size687670-augustus-gene-5.16-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold1014size32369-augustus-gene-0.1-mRNA-1 24 Reactome: R-HSA-392170;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-400042;Reactome: R-HSA-6814122;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-418217;Reactome: R-HSA-428930;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-416476 "ADP signalling through P2Y purinoceptor 12";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"Thromboxane signalling through TP receptor";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"G alpha (q) signalling events" maker-scaffold59size767954-augustus-gene-4.4-mRNA-1 6 Reactome: R-HSA-71336;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1 "Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms" maker-scaffold3494size7281-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" maker-scaffold26size1667613-augustus-gene-4.2-mRNA-1 5 Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;Reactome: R-HSA-6807505 "Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"RNA polymerase II transcribes snRNA genes" maker-scaffold5size1727520-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold805size46428-augustus-gene-0.2-mRNA-1 8 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)" maker-scaffold183size369409-augustus-gene-2.4-mRNA-1 8 Reactome: R-HSA-1855183;MetaCyc: PWY-4661;MetaCyc: PWY-6664;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-6372 "Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" maker-scaffold20size1234842-augustus-gene-10.2-mRNA-1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" maker-scaffold8size1945031-augustus-gene-15.4-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold271size267669-augustus-gene-1.9-mRNA-1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;Reactome: R-HSA-163765 "Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression" maker-scaffold34size991984-augustus-gene-8.6-mRNA-1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" maker-scaffold35size976498-augustus-gene-3.1-mRNA-1 6 Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9640463;Reactome: R-HSA-9029558 "ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"Wax biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" maker-scaffold862size41726-augustus-gene-0.0-mRNA-1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" maker-scaffold1599size17008-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" maker-scaffold145size712617-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold121size481755-augustus-gene-0.4-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold411size152019-augustus-gene-0.5-mRNA-1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" maker-scaffold16size1255579-augustus-gene-4.14-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold4481size16825-augustus-gene-0.1-mRNA-1 6 MetaCyc: PWY-7382;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism" maker-scaffold157size419459-augustus-gene-3.20-mRNA-1 1 Reactome: R-HSA-1483101 "Synthesis of PS" maker-scaffold548size90716-augustus-gene-0.5-mRNA-1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" maker-scaffold37size976698-augustus-gene-3.5-mRNA-1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" maker-scaffold23size1161859-augustus-gene-10.8-mRNA-1 52 Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-203927;Reactome: R-HSA-72165;Reactome: R-HSA-167161;Reactome: R-HSA-76066;Reactome: R-HSA-167246;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-72203;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-5617472;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8851708;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-6803529;Reactome: R-HSA-5250924;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-75953;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-73780;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-5601884;Reactome: R-HSA-167287;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-1834949;Reactome: R-HSA-9018519;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-73863 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"MicroRNA (miRNA) biogenesis";"mRNA Splicing - Minor Pathway";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"Processing of Capped Intron-Containing Pre-mRNA";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Signaling by FGFR2 IIIa TM";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"FGFR2 alternative splicing";"B-WICH complex positively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase III Chain Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"PIWI-interacting RNA (piRNA) biogenesis";"HIV elongation arrest and recovery";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Estrogen-dependent gene expression";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination" maker-scaffold120size483217-augustus-gene-3.2-mRNA-1 7 KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;Reactome: R-HSA-73817;MetaCyc: PWY-7221 "Drug metabolism - other enzymes";"Purine metabolism";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine ribonucleoside monophosphate biosynthesis";"Guanosine ribonucleotides de novo biosynthesis" maker-scaffold228size313446-augustus-gene-2.3-mRNA-1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Neddylation";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex" maker-scaffold47size1319914-augustus-gene-12.4-mRNA-1 13 MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Other glycan degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"CS/DS degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" maker-scaffold78size655360-augustus-gene-1.2-mRNA-1 6 Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" maker-scaffold105size529344-augustus-gene-4.22-mRNA-1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" maker-scaffold112size514619-augustus-gene-2.1-mRNA-1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination" maker-scaffold2942size7664-augustus-gene-0.0-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold23size1161859-augustus-gene-10.0-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold1size2756217-augustus-gene-0.2-mRNA-1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" maker-scaffold54size1273868-augustus-gene-8.4-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold90size602833-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" maker-scaffold813size45733-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" maker-scaffold22size1201825-augustus-gene-7.8-mRNA-1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497 "ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" maker-scaffold509size104404-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-611105 "Respiratory electron transport" maker-scaffold4168size15254-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1483166 "Synthesis of PA" maker-scaffold73size681921-augustus-gene-2.8-mRNA-1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6 "Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine metabolism" maker-scaffold707size55768-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold33size1007119-augustus-gene-4.8-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" maker-scaffold47size1319914-augustus-gene-10.6-mRNA-1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" maker-scaffold26size1667613-augustus-gene-2.2-mRNA-1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" maker-scaffold9size1444705-augustus-gene-4.12-mRNA-1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" maker-scaffold45size832949-augustus-gene-5.2-mRNA-1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72187;MetaCyc: PWY-7511;Reactome: R-HSA-73856;Reactome: R-HSA-72163 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"Protein ubiquitination";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway" maker-scaffold1size2756217-augustus-gene-26.10-mRNA-1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold28size1079920-augustus-gene-1.1-mRNA-1 13 Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" maker-scaffold5434size7673-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold1383size20519-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" maker-scaffold446size134571-augustus-gene-0.5-mRNA-1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" maker-scaffold2size2657229-augustus-gene-8.5-mRNA-1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" maker-scaffold2568size15858-augustus-gene-0.0-mRNA-1 10 Reactome: R-HSA-9635644;Reactome: R-HSA-182971;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-5689880 "Inhibition of membrane repair";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases" maker-scaffold71size686415-augustus-gene-5.15-mRNA-1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" maker-scaffold9size1444705-augustus-gene-10.2-mRNA-1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" maker-scaffold154size420078-augustus-gene-3.3-mRNA-1 18 Reactome: R-HSA-8953750;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;MetaCyc: PWY-7511;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-6804756;Reactome: R-HSA-1221632;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579 "Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Protein ubiquitination";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Regulation of TP53 Activity through Phosphorylation";"Meiotic synapsis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange" augustus-scaffold445size134704-processed-gene-0.0-mRNA-1 5 Reactome: R-HSA-5576886;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-5662702;Reactome: R-HSA-6798695 "Phase 4 - resting membrane potential";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Melanin biosynthesis";"Neutrophil degranulation" maker-scaffold11size1424826-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" maker-scaffold136size447168-augustus-gene-0.4-mRNA-1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold163size408523-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" maker-scaffold315size226392-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" maker-scaffold271size267669-augustus-gene-1.15-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" maker-scaffold72size687670-augustus-gene-5.23-mRNA-1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" augustus-scaffold1236size23564-processed-gene-0.0-mRNA-1 10 MetaCyc: PWY-7210;Reactome: R-HSA-69205;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7198;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7187;MetaCyc: PWY-3841 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"One carbon pool by folate";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Folate transformations II (plants)" maker-scaffold420size146668-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" maker-scaffold11size1424826-augustus-gene-7.6-mRNA-1 8 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway" maker-scaffold549size90356-augustus-gene-0.0-mRNA-1 30 Reactome: R-HSA-5696395;Reactome: R-HSA-72086;Reactome: R-HSA-73772;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-167160;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"mRNA Capping";"RNA Polymerase I Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual Incision in GG-NER" maker-scaffold2747size8298-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold29size1057726-augustus-gene-9.1-mRNA-1 19 MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7291;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7337 "Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)" maker-scaffold209size335547-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" maker-scaffold1133size27339-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold11926size7691-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2408557 "Selenocysteine synthesis" maker-scaffold25size1130848-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" augustus-scaffold5632size2929-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold234size306624-augustus-gene-2.6-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold22size1201825-augustus-gene-11.8-mRNA-1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" maker-scaffold242size299879-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold4261size9984-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-8876725;Reactome: R-HSA-611105 "Protein methylation";"Respiratory electron transport" maker-scaffold3748size9785-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold138size440403-augustus-gene-3.11-mRNA-1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" maker-scaffold113size504212-augustus-gene-3.4-mRNA-1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109 "O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis" maker-scaffold2size2657229-augustus-gene-21.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold200size345481-augustus-gene-2.7-mRNA-1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold649size64880-augustus-gene-0.1-mRNA-1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Glutathione metabolism" maker-scaffold50size801739-augustus-gene-7.9-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold163size408523-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold156size419509-augustus-gene-2.2-mRNA-1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11 "Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis" maker-scaffold6size1916839-augustus-gene-12.2-mRNA-1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" maker-scaffold54size1273868-augustus-gene-11.7-mRNA-1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.25 "Neutrophil degranulation";"Lysosomal oligosaccharide catabolism";"Other glycan degradation" maker-scaffold224size317058-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold39size909063-augustus-gene-1.4-mRNA-1 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" maker-scaffold11size1424826-augustus-gene-10.3-mRNA-1 11 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human papillomavirus infection";"Cytosolic sensors of pathogen-associated DNA";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold25size1130848-augustus-gene-6.9-mRNA-1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" maker-scaffold5954size7244-augustus-gene-0.1-mRNA-1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" maker-scaffold19402size7176-augustus-gene-0.2-mRNA-1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold249size290928-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" maker-scaffold130size553940-augustus-gene-4.1-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold89size602897-augustus-gene-5.19-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold43size857109-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" maker-scaffold1size2756217-augustus-gene-16.0-mRNA-1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold19526size7213-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" maker-scaffold42size1661181-augustus-gene-3.5-mRNA-1 4 Reactome: R-HSA-6807062;MetaCyc: PWY-8026;Reactome: R-HSA-6807047;KEGG: 00100+1.3.1.72 "Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Steroid biosynthesis" maker-scaffold264size273138-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold874size40818-augustus-gene-0.0-mRNA-1 6 KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234 "One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III" maker-scaffold89size602897-augustus-gene-5.16-mRNA-1 56 Reactome: R-HSA-75815;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-69481;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-69017;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091 "Ubiquitin-dependent degradation of Cyclin D";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"G2/M Checkpoints";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Downstream TCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells" maker-scaffold71size686415-augustus-gene-0.5-mRNA-1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6783310 "Ion transport by P-type ATPases";"Fanconi Anemia Pathway" maker-scaffold254size288410-augustus-gene-1.17-mRNA-1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-210500 "D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate Neurotransmitter Release Cycle" maker-scaffold12size1412574-augustus-gene-13.23-mRNA-1 8 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-5140745;Reactome: R-HSA-432720 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis" maker-scaffold21size1197050-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-8963693 "Aspartate and asparagine metabolism" maker-scaffold212size330836-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold210size338753-augustus-gene-2.10-mRNA-1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-8876725 "Stimuli-sensing channels";"Protein methylation" maker-scaffold3size2782310-augustus-gene-4.17-mRNA-1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" maker-scaffold66size1200099-augustus-gene-10.0-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold670size60319-augustus-gene-0.4-mRNA-1 8 KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;MetaCyc: PWY-7817 "Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)" maker-scaffold6353size2713-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" maker-scaffold1320size21658-augustus-gene-0.0-mRNA-1 33 Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168325 "SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Separation of Sister Chromatids";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis" maker-scaffold79size709353-augustus-gene-6.3-mRNA-1 1 Reactome: R-HSA-6798163 "Choline catabolism" maker-scaffold98size575737-augustus-gene-1.0-mRNA-1 6 Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00780+6.3.4.15 "Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Biotin metabolism" maker-scaffold1size2756217-augustus-gene-26.12-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold13size1375079-augustus-gene-11.1-mRNA-1 3 Reactome: R-HSA-727802;Reactome: R-HSA-5619078;Reactome: R-HSA-6787639 "Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis" maker-scaffold3625size11708-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold145size712617-augustus-gene-3.5-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" augustus-scaffold3359size5829-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-611105 "Respiratory electron transport" maker-scaffold130size553940-augustus-gene-1.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold208size344337-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" maker-scaffold1size2756217-augustus-gene-26.14-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold359size198927-augustus-gene-1.3-mRNA-1 6 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-5689880;Reactome: R-HSA-6796648;Reactome: R-HSA-5696400 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"Ub-specific processing proteases";"TP53 Regulates Transcription of DNA Repair Genes";"Dual Incision in GG-NER" maker-scaffold122size477764-augustus-gene-3.7-mRNA-1 4 Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943 "Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" maker-scaffold219size326357-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" maker-scaffold227size314013-augustus-gene-2.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold741size52330-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-427413 "Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression" maker-scaffold152size422804-augustus-gene-1.0-mRNA-1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" maker-scaffold141size440309-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-9640463 "Wax biosynthesis" maker-scaffold6size1916839-augustus-gene-3.8-mRNA-1 3 Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3 "Serine biosynthesis";"Methane metabolism";"Glycine, serine and threonine metabolism" maker-scaffold42size1661181-augustus-gene-12.0-mRNA-1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" maker-scaffold37size976698-augustus-gene-6.6-mRNA-1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" maker-scaffold76size663279-augustus-gene-1.1-mRNA-1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" maker-scaffold112size514619-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" maker-scaffold2355size9996-augustus-gene-0.1-mRNA-1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" maker-scaffold247size292830-augustus-gene-1.6-mRNA-1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol" maker-scaffold45size832949-augustus-gene-7.9-mRNA-1 12 MetaCyc: PWY-7854;Reactome: R-HSA-71032;KEGG: 00640+5.1.99.1;MetaCyc: PWY-7384;MetaCyc: PWY-5789;MetaCyc: PWY-8086;MetaCyc: PWY-5741;KEGG: 00720+5.1.99.1;KEGG: 00280+5.1.99.1;KEGG: 00630+5.1.99.1;MetaCyc: PWY-5743;MetaCyc: PWY-6728 "Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propionyl-CoA catabolism";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Ethylmalonyl-coa pathway";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Glyoxylate and dicarboxylate metabolism";"3-hydroxypropanoate cycle";"Methylaspartate cycle" maker-scaffold2286size15097-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" maker-scaffold4size1754260-augustus-gene-10.2-mRNA-1 17 Reactome: R-HSA-69202;Reactome: R-HSA-139915;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-69656;Reactome: R-HSA-113501;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-2559580;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-2559585;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-111448 "Cyclin E associated events during G1/S transition";"Activation of PUMA and translocation to mitochondria";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"Cyclin A:Cdk2-associated events at S phase entry";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Oxidative Stress Induced Senescence";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Oncogene Induced Senescence";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Cyclin D associated events in G1";"Activation of NOXA and translocation to mitochondria" maker-scaffold126size469926-augustus-gene-3.1-mRNA-1 4 Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750 "Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6" maker-scaffold271size267669-augustus-gene-1.17-mRNA-1 9 KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" maker-scaffold47size1319914-augustus-gene-8.0-mRNA-1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" maker-scaffold2668size8606-augustus-gene-0.1-mRNA-1 9 MetaCyc: PWY-8086;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis";"Biotin transport and metabolism";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency" maker-scaffold10size1426409-augustus-gene-12.3-mRNA-1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" maker-scaffold267size269091-augustus-gene-0.0-mRNA-1 15 KEGG: 00230+2.7.4.3;Reactome: R-HSA-428890;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;KEGG: 00730+2.7.4.3;KEGG: 04660+2.7.10.2;MetaCyc: PWY-7219;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-499943 "Purine metabolism";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"Thiamine metabolism";"T cell receptor signaling pathway";"Adenosine ribonucleotides de novo biosynthesis";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"Interconversion of nucleotide di- and triphosphates" maker-scaffold8size1945031-augustus-gene-18.1-mRNA-1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" maker-scaffold22size1201825-augustus-gene-6.3-mRNA-1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" maker-scaffold21size1197050-augustus-gene-4.5-mRNA-1 6 Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism" maker-scaffold770size49534-augustus-gene-0.0-mRNA-1 7 Reactome: R-HSA-5662702;Reactome: R-HSA-3322077;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18;MetaCyc: PWY-5067;MetaCyc: PWY-622;MetaCyc: PWY-7900 "Melanin biosynthesis";"Glycogen synthesis";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" maker-scaffold284size253718-augustus-gene-1.7-mRNA-1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" maker-scaffold10size1426409-augustus-gene-2.13-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold470size124269-augustus-gene-0.11-mRNA-1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"Late endosomal microautophagy" maker-scaffold56size1152634-augustus-gene-5.1-mRNA-1 4 Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963 "Pyrimidine catabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" maker-scaffold145size712617-augustus-gene-2.1-mRNA-1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold2242size10587-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" maker-scaffold3550size5388-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold24size1136029-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold89size602897-augustus-gene-0.2-mRNA-1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-1989781;Reactome: R-HSA-9029569;Reactome: R-HSA-9022537 "HCMV Early Events";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"PPARA activates gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Loss of MECP2 binding ability to the NCoR/SMRT complex" maker-scaffold5793size9669-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" maker-scaffold6size1916839-augustus-gene-4.0-mRNA-1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" maker-scaffold17size1249603-augustus-gene-11.16-mRNA-1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" maker-scaffold127size531218-augustus-gene-4.2-mRNA-1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" augustus-scaffold937size36937-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold11size1424826-augustus-gene-2.4-mRNA-1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" maker-scaffold383size174942-augustus-gene-0.3-mRNA-1 8 KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00650+4.1.3.4;Reactome: R-HSA-189085;MetaCyc: PWY-5074;KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111;Reactome: R-HSA-9033241 "Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"Digestion of dietary carbohydrate";"Mevalonate degradation";"Geraniol degradation";"Synthesis of Ketone Bodies";"Peroxisomal protein import" maker-scaffold2267size10593-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-156588 "Glucuronidation" maker-scaffold21size1197050-augustus-gene-5.0-mRNA-1 7 Reactome: R-HSA-5579026;Reactome: R-HSA-8939243;Reactome: R-HSA-211976;Reactome: R-HSA-3214858;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Endogenous sterols";"RMTs methylate histone arginines";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis" maker-scaffold45size832949-augustus-gene-4.3-mRNA-1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" maker-scaffold9size1444705-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" maker-scaffold148size437419-augustus-gene-0.0-mRNA-1 14 Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167287;Reactome: R-HSA-167246 "Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript" augustus-scaffold567size85429-processed-gene-0.1-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold84size638750-augustus-gene-4.5-mRNA-1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" maker-scaffold1064size30108-augustus-gene-0.0-mRNA-1 10 KEGG: 00720+1.1.1.42;MetaCyc: PWY-7268;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42 "Carbon fixation pathways in prokaryotes";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Glutathione metabolism";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)" augustus-scaffold995size33530-processed-gene-0.1-mRNA-1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-5514 "Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II" maker-scaffold75size670735-augustus-gene-1.6-mRNA-1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" maker-scaffold9size1444705-augustus-gene-13.10-mRNA-1 7 MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11 "Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Methane metabolism" maker-scaffold75size670735-augustus-gene-3.2-mRNA-1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids" maker-scaffold4530size7933-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-111457;Reactome: R-HSA-111469 "Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response" maker-scaffold352size202783-augustus-gene-1.11-mRNA-1 5 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold118size492329-augustus-gene-2.0-mRNA-1 7 MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-1855204 "2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol" maker-scaffold10968size7697-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" maker-scaffold14size1670589-augustus-gene-9.4-mRNA-1 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" maker-scaffold38size924328-augustus-gene-3.3-mRNA-1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" maker-scaffold138size440403-augustus-gene-3.1-mRNA-1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" maker-scaffold785size48402-augustus-gene-0.1-mRNA-1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" maker-scaffold8size1945031-augustus-gene-10.4-mRNA-1 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" maker-scaffold455size140735-augustus-gene-0.4-mRNA-1 14 MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6598 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis" augustus-scaffold743size51916-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" maker-scaffold31size1053862-augustus-gene-2.11-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold19size1242042-augustus-gene-1.2-mRNA-1 10 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167161;Reactome: R-HSA-76042 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" maker-scaffold256size285501-augustus-gene-1.7-mRNA-1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" maker-scaffold47size1319914-augustus-gene-12.2-mRNA-1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" augustus-scaffold1865size13987-processed-gene-0.0-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold157size419459-augustus-gene-3.12-mRNA-1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold23size1161859-augustus-gene-10.11-mRNA-1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" maker-scaffold84size638750-augustus-gene-4.12-mRNA-1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation" maker-scaffold8size1945031-augustus-gene-4.9-mRNA-1 1 Reactome: R-HSA-8951664 "Neddylation" maker-scaffold72size687670-augustus-gene-5.21-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold73size681921-augustus-gene-4.5-mRNA-1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" maker-scaffold260size277064-augustus-gene-1.13-mRNA-1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" maker-scaffold603size77277-augustus-gene-0.1-mRNA-1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" maker-scaffold397size365563-augustus-gene-2.6-mRNA-1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" maker-scaffold84size638750-augustus-gene-4.0-mRNA-1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" maker-scaffold320size221394-augustus-gene-1.8-mRNA-1 14 KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7782;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;MetaCyc: PWY-8053 "Ether lipid metabolism";"Glycerophospholipid metabolism";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Plasmalogen biosynthesis";"Sphingolipid metabolism";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II" maker-scaffold8size1945031-augustus-gene-17.1-mRNA-1 10 Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-432720;Reactome: R-HSA-8875360 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Inhibition of membrane repair";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell" maker-scaffold219size326357-augustus-gene-1.1-mRNA-1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" maker-scaffold311size229472-augustus-gene-1.3-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold8387size8757-augustus-gene-0.0-mRNA-1 2 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" maker-scaffold191size643645-augustus-gene-2.9-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold4993size3151-augustus-gene-0.0-mRNA-1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" maker-scaffold157size419459-augustus-gene-3.2-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" maker-scaffold138size440403-augustus-gene-3.16-mRNA-1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" maker-scaffold8size1945031-augustus-gene-18.5-mRNA-1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" maker-scaffold19size1242042-augustus-gene-3.0-mRNA-1 7 KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7456;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8 "Fructose and mannose metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism" maker-scaffold2size2657229-augustus-gene-25.26-mRNA-1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" augustus-scaffold1670size16153-processed-gene-0.0-mRNA-1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping" maker-scaffold375size184108-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold68size696256-augustus-gene-6.0-mRNA-1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" maker-scaffold74size672076-augustus-gene-2.0-mRNA-1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" maker-scaffold45size832949-augustus-gene-4.8-mRNA-1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" maker-scaffold423size145723-augustus-gene-0.7-mRNA-1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" maker-scaffold58size769326-augustus-gene-5.2-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" maker-scaffold248size292329-augustus-gene-1.16-mRNA-1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" maker-scaffold242size299879-augustus-gene-0.4-mRNA-1 3 Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961 "Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II" maker-scaffold235size305606-augustus-gene-2.6-mRNA-1 1 Reactome: R-HSA-1300642 "Sperm Motility And Taxes" maker-scaffold6size1916839-augustus-gene-2.0-mRNA-1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" augustus-scaffold1633size16639-processed-gene-0.0-mRNA-1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" maker-scaffold158size418592-augustus-gene-3.3-mRNA-1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" maker-scaffold549size90356-augustus-gene-0.2-mRNA-1 10 KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" maker-scaffold1size2756217-augustus-gene-8.4-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold37846size7215-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" maker-scaffold218size326752-augustus-gene-2.12-mRNA-1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" maker-scaffold136size447168-augustus-gene-3.2-mRNA-1 4 Reactome: R-HSA-6798163;MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285 "Choline catabolism";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis" maker-scaffold12size1412574-augustus-gene-13.13-mRNA-1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" maker-scaffold523size99474-augustus-gene-0.8-mRNA-1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-450408;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-9010553;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-1236978;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-350562;Reactome: R-HSA-180534;Reactome: R-HSA-9020702;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-4608870 "Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Neddylation";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Regulation of expression of SLITs and ROBOs";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cross-presentation of soluble exogenous antigens (endosomes)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Regulation of ornithine decarboxylase (ODC)";"Vpu mediated degradation of CD4";"Interleukin-1 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Asymmetric localization of PCP proteins" maker-scaffold164size409319-augustus-gene-0.3-mRNA-1 19 Reactome: R-HSA-8856825;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-5686938;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471 "Cargo recognition for clathrin-mediated endocytosis";"LDL clearance";"Clathrin-mediated endocytosis";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"VLDL assembly";"Post-translational protein phosphorylation";"Chylomicron assembly";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"VLDL clearance";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class A Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron remodeling";"Scavenging by Class B Receptors" maker-scaffold1size2756217-augustus-gene-4.25-mRNA-1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" maker-scaffold573size83708-augustus-gene-0.1-mRNA-1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082 "Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"RORA activates gene expression" augustus-scaffold1573size17298-processed-gene-0.0-mRNA-1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" maker-scaffold9size1444705-augustus-gene-9.1-mRNA-1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" maker-scaffold248size292329-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" maker-scaffold2276size15003-augustus-gene-0.2-mRNA-1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" maker-scaffold1550size17612-augustus-gene-0.0-mRNA-1 4 Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis" maker-scaffold22size1201825-augustus-gene-5.8-mRNA-1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" maker-scaffold3790size9520-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" maker-scaffold282size258062-augustus-gene-1.1-mRNA-1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" maker-scaffold2599size14382-augustus-gene-0.2-mRNA-1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-1362409 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Chromatin modifying enzymes";"Interleukin-7 signaling";"Mitochondrial iron-sulfur cluster biogenesis" maker-scaffold23size1161859-augustus-gene-1.2-mRNA-1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" augustus-scaffold510size103811-processed-gene-0.1-mRNA-1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" maker-scaffold14size1670589-augustus-gene-15.13-mRNA-1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" maker-scaffold223size319359-augustus-gene-2.6-mRNA-1 5 Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168 "ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)" maker-scaffold185size368400-augustus-gene-2.15-mRNA-1 1 Reactome: R-HSA-525793 "Myogenesis" maker-scaffold231size308180-augustus-gene-2.0-mRNA-1 3 Reactome: R-HSA-202433;Reactome: R-HSA-376176;Reactome: R-HSA-446353 "Generation of second messenger molecules";"Signaling by ROBO receptors";"Cell-extracellular matrix interactions" maker-scaffold269size268280-augustus-gene-1.1-mRNA-1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" maker-scaffold153size420471-augustus-gene-2.0-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold16size1255579-augustus-gene-11.23-mRNA-1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" maker-scaffold86size613819-augustus-gene-3.20-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold19size1242042-augustus-gene-9.2-mRNA-1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" maker-scaffold570size84382-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" augustus-scaffold694size57415-processed-gene-0.2-mRNA-1 1 Reactome: R-HSA-977347 "Serine biosynthesis" maker-scaffold78size655360-augustus-gene-5.5-mRNA-1 16 Reactome: R-HSA-5603041;Reactome: R-HSA-6811558;Reactome: R-HSA-975138;Reactome: R-HSA-1810476;Reactome: R-HSA-209543;Reactome: R-HSA-1257604;Reactome: R-HSA-975155;Reactome: R-HSA-975110;Reactome: R-HSA-975871;Reactome: R-HSA-5603037;Reactome: R-HSA-5602498;Reactome: R-HSA-3134963;Reactome: R-HSA-166058;Reactome: R-HSA-1236974;Reactome: R-HSA-5602680;Reactome: R-HSA-9020702 "IRAK4 deficiency (TLR2/4)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"RIP-mediated NFkB activation via ZBP1";"p75NTR recruits signalling complexes";"PIP3 activates AKT signaling";"MyD88 dependent cascade initiated on endosome";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"MyD88 cascade initiated on plasma membrane";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"ER-Phagosome pathway";"MyD88 deficiency (TLR5)";"Interleukin-1 signaling" maker-scaffold294size242463-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-163765 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression" maker-scaffold531size95887-augustus-gene-0.2-mRNA-1 6 Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" maker-scaffold24size1136029-augustus-gene-3.13-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" maker-scaffold10size1426409-augustus-gene-2.12-mRNA-1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" maker-scaffold1489size18786-augustus-gene-0.1-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold22size1201825-augustus-gene-1.1-mRNA-1 3 KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077 "Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis" maker-scaffold604size77144-augustus-gene-0.3-mRNA-1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-450520;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-69273;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "MAPK6/MAPK4 signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Cyclin A/B1/B2 associated events during G2/M transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" maker-scaffold3size2782310-augustus-gene-4.9-mRNA-1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" maker-scaffold54size1273868-augustus-gene-11.8-mRNA-1 9 MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"Nitrogen metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" maker-scaffold273size264890-augustus-gene-1.5-mRNA-1 3 Reactome: R-HSA-8983711;Reactome: R-HSA-877300;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon gamma signaling";"Interferon alpha/beta signaling" maker-scaffold122size477764-augustus-gene-1.3-mRNA-1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" maker-scaffold84size638750-augustus-gene-4.11-mRNA-1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" maker-scaffold10size1426409-augustus-gene-2.1-mRNA-1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" maker-scaffold318size381727-augustus-gene-2.4-mRNA-1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" maker-scaffold8size1945031-augustus-gene-6.7-mRNA-1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation" maker-scaffold22size1201825-augustus-gene-4.1-mRNA-1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" maker-scaffold164size409319-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" maker-scaffold2size2657229-augustus-gene-5.3-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold76size663279-augustus-gene-4.5-mRNA-1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" maker-scaffold279size261100-augustus-gene-1.2-mRNA-1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" maker-scaffold82size640827-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold548size90716-augustus-gene-0.6-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold110size515606-augustus-gene-3.5-mRNA-1 13 MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-5122;MetaCyc: PWY-6859;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-7182;MetaCyc: PWY-7410 "Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Geranyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Terpenoid backbone biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Linalool biosynthesis I";"Ipsdienol biosynthesis" maker-scaffold37size976698-augustus-gene-4.1-mRNA-1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-6784531 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus" maker-scaffold43size857109-augustus-gene-4.12-mRNA-1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Lysine degradation" maker-scaffold52size909272-augustus-gene-2.0-mRNA-1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Amino acids regulate mTORC1" maker-scaffold42size1661181-augustus-gene-13.1-mRNA-1 8 KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" maker-scaffold375size184108-augustus-gene-0.3-mRNA-1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7601 "Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" maker-scaffold2size2657229-augustus-gene-16.0-mRNA-1 4 Reactome: R-HSA-6807062;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.72;Reactome: R-HSA-6807047 "Cholesterol biosynthesis via lathosterol";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis via desmosterol" maker-scaffold157size419459-augustus-gene-3.19-mRNA-1 4 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" maker-scaffold12size1412574-augustus-gene-2.2-mRNA-1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" maker-scaffold80size1421260-augustus-gene-8.0-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold251size291382-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" maker-scaffold208size344337-augustus-gene-1.4-mRNA-1 8 MetaCyc: PWY-7179;Reactome: R-HSA-5683826;Reactome: R-HSA-6798695;MetaCyc: PWY-6611;KEGG: 00230+3.5.4.4;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609 "Purine deoxyribonucleosides degradation I";"Surfactant metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage V";"Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III" maker-scaffold4size1754260-augustus-gene-6.1-mRNA-1 40 Reactome: R-HSA-167287;Reactome: R-HSA-5601884;Reactome: R-HSA-167160;Reactome: R-HSA-6781827;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-167243;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-72203;Reactome: R-HSA-5578749;Reactome: R-HSA-167152;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-6803529;Reactome: R-HSA-113418 "HIV elongation arrest and recovery";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Transcriptional regulation by small RNAs";"Formation of HIV elongation complex in the absence of HIV Tat";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex" maker-scaffold717size54285-augustus-gene-0.1-mRNA-1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-5687128;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-9018519 "Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression" maker-scaffold6size1916839-augustus-gene-18.2-mRNA-1 56 Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5689603;Reactome: R-HSA-8941858;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-69601;Reactome: R-HSA-5658442;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541 "Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"UCH proteinases";"Regulation of RUNX3 expression and activity";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RAS by GAPs";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"ER-Phagosome pathway";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway" maker-scaffold1size2756217-augustus-gene-26.2-mRNA-1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" maker-scaffold814size45690-augustus-gene-0.1-mRNA-1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" maker-scaffold544size92723-augustus-gene-0.2-mRNA-1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" maker-scaffold1size2756217-augustus-gene-8.8-mRNA-1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" maker-scaffold258size282563-augustus-gene-1.1-mRNA-1 3 KEGG: 00400+2.7.1.71;MetaCyc: PWY-6163;KEGG: 00400+2.5.1.19 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Chorismate biosynthesis from 3-dehydroquinate";"Phenylalanine, tyrosine and tryptophan biosynthesis" maker-scaffold222size322023-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" maker-scaffold1size2756217-augustus-gene-12.3-mRNA-1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" maker-scaffold367size190875-augustus-gene-0.10-mRNA-1 6 MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" maker-scaffold43size857109-augustus-gene-4.14-mRNA-1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold1size2756217-augustus-gene-16.8-mRNA-1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" maker-scaffold185size368400-augustus-gene-2.5-mRNA-1 7 Reactome: R-HSA-983170;Reactome: R-HSA-381042;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-114608 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"PERK regulates gene expression";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation" maker-scaffold1012size32445-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" maker-scaffold33size1007119-augustus-gene-4.7-mRNA-1 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation" maker-scaffold546size91324-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" maker-scaffold470size124269-augustus-gene-0.7-mRNA-1 24 Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-8955332;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Separation of Sister Chromatids" maker-scaffold368size189170-augustus-gene-0.0-mRNA-1 8 KEGG: 00950+1.4.3.21;KEGG: 00410+1.4.3.21;Reactome: R-HSA-211945;KEGG: 00960+1.4.3.21;MetaCyc: PWY-5751;KEGG: 00350+1.4.3.21;KEGG: 00360+1.4.3.21;KEGG: 00260+1.4.3.21 "Isoquinoline alkaloid biosynthesis";"beta-Alanine metabolism";"Phase I - Functionalization of compounds";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylethanol biosynthesis";"Tyrosine metabolism";"Phenylalanine metabolism";"Glycine, serine and threonine metabolism" maker-scaffold29size1057726-augustus-gene-7.0-mRNA-1 44 Reactome: R-HSA-5673001;Reactome: R-HSA-2029482;Reactome: R-HSA-444257;Reactome: R-HSA-6811558;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-5675221;Reactome: R-HSA-8940973;Reactome: R-HSA-5654727;Reactome: R-HSA-3371453;Reactome: R-HSA-5654733;Reactome: R-HSA-170968;Reactome: R-HSA-456926;Reactome: R-HSA-6802946;Reactome: R-HSA-2559585;Reactome: R-HSA-5668599;Reactome: R-HSA-5663213;Reactome: R-HSA-8943724;Reactome: R-HSA-982772;Reactome: R-HSA-6802955;Reactome: R-HSA-2871796;Reactome: R-HSA-2559582;Reactome: R-HSA-881907;Reactome: R-HSA-112409;Reactome: R-HSA-198753;KEGG: 04150+2.7.11.24;Reactome: R-HSA-445144;Reactome: R-HSA-9634638;Reactome: R-HSA-6802952;Reactome: R-HSA-375165;Reactome: R-HSA-2559580;Reactome: R-HSA-1295596;Reactome: R-HSA-162658;Reactome: R-HSA-9627069;Reactome: R-HSA-879415;Reactome: R-HSA-5674499;Reactome: R-HSA-450341;Reactome: R-HSA-9635465;Reactome: R-HSA-8939211;Reactome: R-HSA-202670;Reactome: R-HSA-5654732;Reactome: R-HSA-5654726;Reactome: R-HSA-74749 "RAF/MAP kinase cascade";"Regulation of actin dynamics for phagocytic cup formation";"RSK activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"RUNX2 regulates osteoblast differentiation";"Negative regulation of FGFR2 signaling";"Regulation of HSF1-mediated heat shock response";"Negative regulation of FGFR4 signaling";"Frs2-mediated activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by moderate kinase activity BRAF mutants";"Oncogene Induced Senescence";"RHO GTPases Activate NADPH Oxidases";"RHO GTPases Activate WASPs and WAVEs";"Regulation of PTEN gene transcription";"Growth hormone receptor signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"FCERI mediated MAPK activation";"Senescence-Associated Secretory Phenotype (SASP)";"Gastrin-CREB signalling pathway via PKC and MAPK";"RAF-independent MAPK1/3 activation";"ERK/MAPK targets";"mTOR signaling pathway";"Signal transduction by L1";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by BRAF and RAF fusions";"NCAM signaling for neurite out-growth";"Oxidative Stress Induced Senescence";"Spry regulation of FGF signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of the apoptosome activity";"Advanced glycosylation endproduct receptor signaling";"Negative feedback regulation of MAPK pathway";"Activation of the AP-1 family of transcription factors";"Suppression of apoptosis";"ESR-mediated signaling";"ERKs are inactivated";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR1 signaling";"Signal attenuation" maker-scaffold1size2756217-augustus-gene-7.3-mRNA-1 56 Reactome: R-HSA-211733;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-1236978;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4608870;Reactome: R-HSA-382556;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-69481;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-174178 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Orc1 removal from chromatin";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Cross-presentation of soluble exogenous antigens (endosomes)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Asymmetric localization of PCP proteins";"ABC-family proteins mediated transport";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"G2/M Checkpoints";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" maker-scaffold5size1727520-augustus-gene-2.0-mRNA-1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" maker-scaffold10size1426409-augustus-gene-5.5-mRNA-1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" maker-scaffold49size896674-augustus-gene-6.4-mRNA-1 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" maker-scaffold1size2756217-augustus-gene-23.2-mRNA-1 5 Reactome: R-HSA-450341;Reactome: R-HSA-2871796;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580 "Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"Oxidative Stress Induced Senescence" maker-scaffold267size269091-augustus-gene-1.12-mRNA-1 1 Reactome: R-HSA-611105 "Respiratory electron transport" maker-scaffold156size419509-augustus-gene-3.22-mRNA-1 12 Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380320 "XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes" maker-scaffold34069size7329-augustus-gene-0.2-mRNA-1 4 Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-2395516 "Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin" maker-scaffold129size456722-augustus-gene-3.1-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold37size976698-augustus-gene-7.2-mRNA-1 1 Reactome: R-HSA-5676934 "Protein repair" maker-scaffold136size447168-augustus-gene-0.1-mRNA-1 9 Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-430039;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"mRNA decay by 5' to 3' exoribonuclease";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" maker-scaffold290size245803-augustus-gene-0.0-mRNA-1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" maker-scaffold1901size13614-augustus-gene-0.1-mRNA-1 14 KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-3781;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-7279;MetaCyc: PWY-6969;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-7254;KEGG: 00650+1.3.5.1 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration I (cytochrome c)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"TCA cycle VII (acetate-producers)";"Butanoate metabolism" maker-scaffold177size387897-augustus-gene-2.2-mRNA-1 3 Reactome: R-HSA-5678771;Reactome: R-HSA-1989781;Reactome: R-HSA-382556 "Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression";"ABC-family proteins mediated transport" maker-scaffold2832size8280-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" maker-scaffold101size554424-augustus-gene-1.3-mRNA-1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" maker-scaffold364size352455-augustus-gene-2.3-mRNA-1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" maker-scaffold306size232476-augustus-gene-1.2-mRNA-1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" maker-scaffold18size2240851-augustus-gene-12.1-mRNA-1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" maker-scaffold80size1421260-augustus-gene-3.1-mRNA-1 13 KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism" maker-scaffold157size419459-augustus-gene-2.2-mRNA-1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" maker-scaffold559size87523-augustus-gene-0.1-mRNA-1 6 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex" augustus-scaffold2265size10456-processed-gene-0.1-mRNA-1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" maker-scaffold43size857109-augustus-gene-4.24-mRNA-1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" maker-scaffold12size1412574-augustus-gene-6.1-mRNA-1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" maker-scaffold7759size7999-augustus-gene-0.0-mRNA-1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" maker-scaffold1size2756217-augustus-gene-26.4-mRNA-1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" maker-scaffold187size362697-augustus-gene-2.7-mRNA-1 1 Reactome: R-HSA-8963684 "Tyrosine catabolism" maker-scaffold84size638750-augustus-gene-5.8-mRNA-1 13 Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5099900 "Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD4" maker-scaffold2486size20878-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold157size419459-augustus-gene-3.1-mRNA-1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-4615885;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-1169408 "Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"SUMOylation of DNA replication proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"ISG15 antiviral mechanism" maker-scaffold169size953240-augustus-gene-5.8-mRNA-1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" maker-scaffold449size132165-augustus-gene-0.3-mRNA-1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" maker-scaffold1size2756217-augustus-gene-24.4-mRNA-1 1 Reactome: R-HSA-189200 "Cellular hexose transport" maker-scaffold1135size27289-augustus-gene-0.0-mRNA-1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" maker-scaffold5size1727520-augustus-gene-14.2-mRNA-1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" maker-scaffold642size70303-augustus-gene-0.2-mRNA-1 3 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" maker-scaffold28size1079920-augustus-gene-1.5-mRNA-1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" maker-scaffold266size269306-augustus-gene-1.20-mRNA-1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" maker-scaffold210size338753-augustus-gene-2.13-mRNA-1 7 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-2467813 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids" maker-scaffold22size1201825-augustus-gene-4.27-mRNA-1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" maker-scaffold542size93235-augustus-gene-0.5-mRNA-1 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" maker-scaffold2size2657229-augustus-gene-17.11-mRNA-1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" maker-scaffold463size137807-augustus-gene-0.2-mRNA-1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" maker-scaffold65size703589-augustus-gene-6.3-mRNA-1 3 Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482 "Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events" maker-scaffold2size2657229-augustus-gene-25.5-mRNA-1 13 Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" maker-scaffold165size402902-augustus-gene-3.2-mRNA-1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" maker-scaffold464size126411-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2408557 "Selenocysteine synthesis" maker-scaffold136size447168-augustus-gene-3.4-mRNA-1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" maker-scaffold164size409319-augustus-gene-1.3-mRNA-1 11 Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" augustus-scaffold2052size12156-processed-gene-0.0-mRNA-1 3 Reactome: R-HSA-70350;Reactome: R-HSA-168928;KEGG: 00480+3.4.11.1 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Glutathione metabolism" maker-scaffold397size365563-augustus-gene-2.5-mRNA-1 1 Reactome: R-HSA-71384 "Ethanol oxidation" maker-scaffold1size2756217-augustus-gene-8.7-mRNA-1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" maker-scaffold383size174942-augustus-gene-0.1-mRNA-1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" maker-scaffold276size261909-augustus-gene-1.3-mRNA-1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold76size663279-augustus-gene-4.4-mRNA-1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" maker-scaffold19size1242042-augustus-gene-0.3-mRNA-1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" augustus-scaffold3444size18044-processed-gene-0.0-mRNA-1 11 MetaCyc: PWY-6549;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7254;MetaCyc: PWY-7268;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-6969;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728 "L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glutathione metabolism";"Methylaspartate cycle" maker-scaffold7589size7897-augustus-gene-0.1-mRNA-1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" maker-scaffold6size1916839-augustus-gene-14.0-mRNA-1 3 MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K" augustus-scaffold1337size21277-processed-gene-0.1-mRNA-1 23 KEGG: 00770+2.7.1.33;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-6811555;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-6804756;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-5668599;MetaCyc: PWY-3961;Reactome: R-HSA-936440 "Pantothenate and CoA biosynthesis";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"PI5P Regulates TP53 Acetylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of TP53 Activity through Phosphorylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"RHO GTPases Activate NADPH Oxidases";"Phosphopantothenate biosynthesis II";"Negative regulators of DDX58/IFIH1 signaling" maker-scaffold59size767954-augustus-gene-3.3-mRNA-1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis" maker-scaffold10size1426409-augustus-gene-11.0-mRNA-1 1 Reactome: R-HSA-191859 "snRNP Assembly" maker-scaffold110size515606-augustus-gene-3.7-mRNA-1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" maker-scaffold572size84276-augustus-gene-0.0-mRNA-1 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic" maker-scaffold5151size3081-augustus-gene-0.0-mRNA-1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" maker-scaffold80size1421260-augustus-gene-2.3-mRNA-1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670 "Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis" maker-scaffold168size400726-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" maker-scaffold13size1375079-augustus-gene-4.26-mRNA-1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" maker-scaffold3381size5753-augustus-gene-0.1-mRNA-1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" maker-scaffold48size811354-augustus-gene-6.2-mRNA-1 1 MetaCyc: PWY-7511 "Protein ubiquitination" maker-scaffold876size40673-augustus-gene-0.1-mRNA-1 4 Reactome: R-HSA-8949664;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Processing of SMDT1";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" maker-scaffold214size663695-augustus-gene-1.1-mRNA-1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" maker-scaffold523size99474-augustus-gene-0.9-mRNA-1 17 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5358565 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" augustus-scaffold3170size6572-processed-gene-0.0-mRNA-1 27 Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638 "NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins" maker-scaffold110size515606-augustus-gene-4.2-mRNA-1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226 "ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol" maker-scaffold185size368400-augustus-gene-2.7-mRNA-1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"