Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_054004211.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_054014969.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053999249.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054016386.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054009242.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054006612.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053998908.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054000947.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053999310.1	6	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_054014037.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998259.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054007515.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054003963.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998828.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_054015575.1	24	Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-8852276;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-380320	"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"Cilium Assembly";"Recycling pathway of L1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes"
XP_054000467.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054001182.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054003443.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054009994.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation"
XP_054004815.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054014449.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN"
XP_053995484.1	57	Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8854050	"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_054011583.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_054016780.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054006677.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_054015846.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054011861.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053997448.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054001643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053996814.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_053996948.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054002336.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998560.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Ub-specific processing proteases";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054002876.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053998174.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054011165.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054015038.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054002064.1	7	MetaCyc: PWY-7198;MetaCyc: PWY-7185;MetaCyc: PWY-7184;MetaCyc: PWY-7210;KEGG: 00730+3.6.1.15;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism"
XP_054002890.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054009927.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_054007532.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053998721.1	10	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"HATs acetylate histones"
XP_053996057.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054016052.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054010160.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_054002955.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054002662.1	4	MetaCyc: PWY-8072;MetaCyc: PWY-7383;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1	"Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis";"D-Alanine metabolism"
XP_054001464.1	4	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-1912420	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi"
XP_054016790.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054008415.1	13	KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;Reactome: R-HSA-499943	"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates"
XP_053995262.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_054008847.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656	"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling"
XP_054016604.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_054012633.1	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_054016830.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053996716.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"EPH-ephrin mediated repulsion of cells";"Formation of annular gap junctions";"Gap junction degradation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054015911.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054016370.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054006994.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2	"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism"
XP_054014026.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053997169.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054011740.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_054004641.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Glycolysis";"Chitin derivatives degradation"
XP_053995256.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054006242.1	3	Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I"
XP_053998230.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054006471.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054014863.1	8	Reactome: R-HSA-4551638;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580	"SUMOylation of chromatin organization proteins";"Regulation of PTEN gene transcription";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence"
XP_054001944.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054016776.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_053996310.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054003869.1	5	MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_054015081.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_054010843.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054006142.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054011416.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones"
XP_053999468.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_054009635.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054010509.1	19	Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class H Receptors";"LDL remodeling";"Chylomicron assembly";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Chylomicron remodeling";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054005550.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation"
XP_054000507.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053995427.1	3	Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426	"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)"
XP_054003056.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054007427.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054002880.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053996960.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_054001579.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_054006807.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054016809.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_054009936.1	42	Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-3214858;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-110328;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-171306;Reactome: R-HSA-5250924;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-8939236;Reactome: R-HSA-9610379;Reactome: R-HSA-73772;Reactome: R-HSA-5334118;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-427359;Reactome: R-HSA-3214841;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-212300;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-5578749;Reactome: R-HSA-912446	"HDACs deacetylate histones";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"RMTs methylate histone arginines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Packaging Of Telomere Ends";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HCMV Late Events";"RNA Polymerase I Promoter Escape";"DNA methylation";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SIRT1 negatively regulates rRNA expression";"PKMTs methylate histone lysines";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"PRC2 methylates histones and DNA";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs";"Meiotic recombination"
XP_054015361.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054008102.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_054008432.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_053998958.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_054014268.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_054015526.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053998209.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_054002800.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054012724.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054012393.1	9	Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054001594.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6783310	"Protein ubiquitination";"Fanconi Anemia Pathway"
XP_053998931.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053995454.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_054011463.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054007170.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054006887.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012335.1	16	Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048	"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_053999073.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_054012773.1	4	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions";"ECM proteoglycans"
XP_054002920.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054009897.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_054001152.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053999622.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054009629.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054013810.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_054010589.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_054007270.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942	"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)"
XP_053996367.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054004090.1	4	Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_054006544.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054004864.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1"
XP_054001266.1	10	Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736	"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors"
XP_054016421.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054000844.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054000918.1	9	KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-6983;MetaCyc: PWY-7442	"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_054015110.1	13	MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5913;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5392	"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II"
XP_054006726.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053997347.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_053998189.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053995196.1	16	Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-141430	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex"
XP_054005590.1	12	MetaCyc: PWY-6936;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-7901;KEGG: 00270+4.4.1.13;KEGG: 00380+2.6.1.7;Reactome: R-HSA-71240;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-2821;MetaCyc: PWY-1187	"Seleno-amino acid biosynthesis (plants)";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Cysteine and methionine metabolism";"Tryptophan metabolism";"Tryptophan catabolism";"Glutathione-mediated detoxification II";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine"
XP_054009775.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054003145.1	13	MetaCyc: PWY-6545;Reactome: R-HSA-74259;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Purine metabolism";"Starch and sucrose metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis"
XP_053997590.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054016082.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054005141.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054009824.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_054007479.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_054001527.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053996588.1	7	KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539	"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism"
XP_054003096.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054008643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054000368.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054002799.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054012797.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999097.1	10	Reactome: R-HSA-3214847;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756	"HATs acetylate histones";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation"
XP_053997472.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053998480.1	33	Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236	"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054003841.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_054010647.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054003070.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_053997743.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054015001.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-3065676;Reactome: R-HSA-3065678	"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_054005576.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054004669.1	10	Reactome: R-HSA-9627069;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-611105;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201	"Regulation of the apoptosome activity";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis"
XP_054011114.1	6	Reactome: R-HSA-9029569;Reactome: R-HSA-1989781;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9022692	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"PPARA activates gene expression";"HCMV Early Events";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity"
XP_053996261.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054002015.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054013055.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053995186.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053998199.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching"
XP_054003034.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054011849.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053998299.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_054016013.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054007286.1	27	Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531	"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus"
XP_054003352.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054003632.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054008818.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053997525.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054002428.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-69205	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G1/S-Specific Transcription"
XP_054007328.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054003521.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054004910.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-400206	"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha"
XP_054006629.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994	"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_054016739.1	3	Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801	"Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)"
XP_053999161.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054010961.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054004025.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-5668;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;KEGG: 00564+2.7.8.5	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Synthesis of PG";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_053998572.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054008579.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_053999917.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway";"Estrogen-dependent gene expression"
XP_054001536.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis"
XP_053996598.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054003086.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054006873.1	5	Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16	"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway"
XP_053999763.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054011503.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053995404.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054014461.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_054016694.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054007404.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054001202.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_054000746.1	15	Reactome: R-HSA-9665251;Reactome: R-HSA-1236382;Reactome: R-HSA-9665233;Reactome: R-HSA-1227986;Reactome: R-HSA-9665246;Reactome: R-HSA-9652282;Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-9665245;Reactome: R-HSA-9665250;Reactome: R-HSA-9665247;Reactome: R-HSA-9664565;Reactome: R-HSA-8863795;Reactome: R-HSA-5637810;Reactome: R-HSA-9634285	"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to trastuzumab";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to neratinib";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to osimertinib";"Signaling by ERBB2 KD Mutants";"Downregulation of ERBB2 signaling";"Constitutive Signaling by EGFRvIII";"Constitutive Signaling by Overexpressed ERBB2"
XP_053998018.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054012605.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_054008113.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_054006824.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_054016700.1	6	Reactome: R-HSA-1660517;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64	"Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_054001102.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053998517.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_054002995.1	6	Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722	"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_054005611.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054013314.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054008213.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_054004766.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053997611.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054006791.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054008079.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999844.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054003482.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism"
XP_054005910.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_053999918.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway";"Estrogen-dependent gene expression"
XP_054007121.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054001036.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053998300.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_054002971.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054001243.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054009781.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053995606.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_054000531.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053995221.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054016154.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054014640.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_054007774.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054014051.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998706.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing"
XP_054012120.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054006135.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054007723.1	10	Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-917729	"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054011952.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054010732.1	7	Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-176187	"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress"
XP_054016254.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_054000073.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921	"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation"
XP_054011446.1	57	Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481	"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints"
XP_054000024.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054012220.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_053997080.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053996597.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054015551.1	14	Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569	"Estrogen-dependent gene expression";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054008332.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054009642.1	10	Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9615017;Reactome: R-HSA-400206	"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of lipid metabolism by PPARalpha"
XP_054013646.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054005766.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659	"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"Signaling by SCF-KIT";"RET signaling"
XP_053996219.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_054005360.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053997025.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_054011316.1	4	MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism";"Choline degradation IV"
XP_054007327.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054016179.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_054012185.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053995759.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_054012798.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999098.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation"
XP_054009193.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_054005090.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_053996587.1	7	MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;Reactome: R-HSA-5628897	"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"TP53 Regulates Metabolic Genes"
XP_054000367.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053997090.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054009293.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054006183.1	8	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG"
XP_054003596.1	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_053997702.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053998609.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054008602.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054015501.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054003492.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053999410.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription"
XP_053997076.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054001613.1	3	KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism"
XP_054010648.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008004.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053996368.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054006455.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_054016104.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_054012133.1	3	Reactome: R-HSA-212676;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361	"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins"
XP_054001094.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_054009738.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054011902.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054012195.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054009898.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054006565.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054004417.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053999573.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054007064.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054014001.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053998756.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054004576.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054013749.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_054006888.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054003413.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244	"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation"
XP_054000865.1	9	Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351	"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053998924.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054007545.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054008769.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_054002206.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_054010919.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054000917.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151	"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_054013116.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054012891.1	12	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Rho GTPase cycle";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054005348.1	5	KEGG: 00260+2.3.1.37;MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00860+2.3.1.37;MetaCyc: PWY-5189	"Glycine, serine and threonine metabolism";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)"
XP_053998973.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054009212.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_054002106.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_053998350.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054004472.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_053996649.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054011578.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054005641.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053997641.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054013761.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054003645.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054010009.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054005050.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054009420.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053995428.1	7	KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;MetaCyc: PWY-5265;Reactome: R-HSA-446193;MetaCyc: PWY-6471	"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)"
XP_054015765.1	11	MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782	"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis"
XP_054016184.1	17	Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-8951664;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-8853884	"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Neddylation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX"
XP_054003556.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054000508.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054003466.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011077.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053998884.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054004269.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_054000310.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_054014911.1	16	Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1236394;Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342	"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling"
XP_053998957.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_054003452.1	4	Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054004169.1	9	KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18	"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione conjugation";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Drug metabolism - cytochrome P450"
XP_054011614.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053995670.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054002404.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054014361.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Signaling by Hippo";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054009678.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_054007850.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053995789.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054010802.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_053998836.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054001054.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053999222.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054009485.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054014526.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_054010341.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118	"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors"
XP_054015268.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053995995.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination"
XP_054008848.1	4	Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763	"MET receptor recycling";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction"
XP_054010922.1	12	MetaCyc: PWY-5857;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5870;Reactome: R-HSA-2142789	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis"
XP_054006203.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054010030.1	18	Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803	"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing"
XP_053995933.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins"
XP_054001872.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054008914.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69202	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition"
XP_054004550.1	14	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-141444;Reactome: R-HSA-5663220	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins"
XP_054008084.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054016043.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054016236.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054000440.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_054007696.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054016406.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_054015610.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054016136.1	6	Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081	"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"MET activates PTK2 signaling"
XP_054014575.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054002296.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_054010866.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011144.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_053999661.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054004500.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053997713.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_053997447.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054008528.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_054016566.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054012342.1	3	Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514	"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_053998894.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_054000619.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054014846.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_053998325.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_054005211.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053995800.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054014091.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053997967.1	4	MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27	"2,4-dinitrotoluene degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_054007800.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-7282	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_054011992.1	4	Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_054012493.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053996058.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_054010672.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054006153.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054010852.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054002170.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320	"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Anchoring fibril formation"
XP_054010023.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053997111.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054012205.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054016552.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054015037.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054006253.1	13	Reactome: R-HSA-3928663;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097	"EPHA-mediated growth cone collapse";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"Human immunodeficiency virus 1 infection";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway"
XP_054003232.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_054014038.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054015319.1	5	MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III"
XP_054013595.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_054008094.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054003132.1	57	Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442	"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs"
XP_054003402.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054009433.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_054006229.1	5	Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948	"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling downstream of RAS mutants"
XP_054015075.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054006678.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_054013071.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053996222.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054005792.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_054000558.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054001769.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_054006129.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_053995839.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_053996122.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Neutrophil degranulation";"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_054007799.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-7282;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277	"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_054000468.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054005372.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054011775.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011333.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054012555.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_054005069.1	11	Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167246	"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_053996437.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054000803.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054007062.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054011904.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_054016432.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054013881.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_053996107.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_054010836.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054015281.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054010376.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054004150.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054004474.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_053998030.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_054001306.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054014388.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054008929.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054003427.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932	"Trafficking of AMPA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"HSF1-dependent transactivation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB"
XP_054007056.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054013185.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054007382.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053999698.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054009553.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053995382.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_053997690.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054008776.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-141444	"MHC class II antigen presentation";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054008396.1	6	MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5744;Reactome: R-HSA-196780	"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Glyoxylate assimilation";"Biotin transport and metabolism"
XP_054009463.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053997389.1	9	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Inositol phosphate metabolism";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis"
XP_054011897.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053997862.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054011737.1	4	MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053999157.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-9609690	"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events"
XP_054000108.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_054001739.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054015900.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054011278.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054010957.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054001627.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_054003156.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054008953.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053998009.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054003494.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054008002.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054013563.1	4	MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4	"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis"
XP_054014068.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_054003262.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_054006849.1	11	Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange"
XP_054016415.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053997856.1	7	Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-2151201	"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Mitochondrial protein import";"Cristae formation";"Photosynthesis";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_054014567.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054016847.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054003162.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_054008370.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_054014778.1	8	MetaCyc: PWY-6580;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6664;MetaCyc: PWY-6372;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661	"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)"
XP_053996631.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054013195.1	6	MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-2426168;Reactome: R-HSA-446199;Reactome: R-HSA-191273	"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis"
XP_054009644.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_054006214.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054013133.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_054010786.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8	"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_054006114.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054004139.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997806.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054008334.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_054004409.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054013233.1	17	Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-69166	"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate"
XP_054004011.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054008874.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_054013891.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054016028.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054000697.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054008066.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade"
XP_054003621.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs"
XP_054015324.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_054003206.1	4	MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_054003436.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"RAF activation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_054011385.1	4	MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-7887	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation"
XP_054016527.1	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA"
XP_054003106.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_054006529.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_054010907.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054007443.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053999301.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054013838.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054002343.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_054004430.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054016166.1	6	MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709	"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins"
XP_054011726.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054001356.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_054011603.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054014040.1	5	MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_053996698.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_054002164.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_054015408.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_054014331.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;MetaCyc: PWY-5381;Reactome: R-HSA-1368108	"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_054006463.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054014651.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054000930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054001889.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_054011065.1	5	Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24	"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions";"NOD1/2 Signaling Pathway";"mTOR signaling pathway"
XP_054014871.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053996257.1	13	MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-2424491	"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling"
XP_054012505.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054000022.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053998617.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_054000755.1	30	Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-5610780;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-917937;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-195253	"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Prolactin receptor signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI1 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex"
XP_054008386.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053999688.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053996157.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_053997779.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054000624.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054005680.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054007392.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_053997511.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_053995392.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054004280.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_054015151.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-114608	"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation"
XP_054003134.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054004728.1	7	MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301	"Phytate degradation I";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis"
XP_054014358.1	5	Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_054003404.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054006512.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_054016213.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_054003234.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_053999381.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054012414.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_053995615.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054000812.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054009165.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054012868.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054015855.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054005794.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_054015753.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761	"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_054005374.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054010659.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054000337.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054005834.1	6	MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;KEGG: 00790+4.2.3.12	"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Folate biosynthesis"
XP_053998813.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_053999608.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-9018519;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation"
XP_054010339.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054000657.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_054011927.1	56	Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974	"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway"
XP_054009265.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_053996224.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054007916.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054016579.1	6	MetaCyc: PWY-2221;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165	"Entner-Doudoroff pathway III (semi-phosphorylative)";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)"
XP_054006577.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_054013758.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053995521.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054010706.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_054012344.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054011471.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_054001543.1	4	KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603	"Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine"
XP_053999061.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054012761.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_054008739.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054001776.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054013483.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_054016818.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054002466.1	7	KEGG: 00620+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_054011142.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054001396.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054000401.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054000019.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054001790.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054016464.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054011305.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1	"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_054002946.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054006535.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_054007760.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054010987.1	3	Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_053999187.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054001830.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054000733.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054010623.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_053995632.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054000375.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054015637.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_054000795.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054004901.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_054010854.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054010300.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054005639.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_054010674.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053997727.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999287.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054009416.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053999173.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054001725.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_054011355.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054007070.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054010762.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054008912.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_054001874.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012533.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053999124.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054002232.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054000188.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054010924.1	12	MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5870	"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_053997784.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054001052.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054010804.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_054005784.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054010630.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054004951.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054000326.1	11	KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054013708.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054007145.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787	"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state"
XP_054012840.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054016643.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054007096.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053996381.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054000561.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054004290.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755583;MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108	"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis"
XP_054001066.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036	"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II"
XP_054008082.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054008356.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-445144	"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Signal transduction by L1"
XP_054005041.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054000785.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053999297.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054009535.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054016182.1	17	Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582	"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)"
XP_053999658.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053996187.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054009593.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-7214;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_053999197.1	60	KEGG: 00623+1.1.1.35;Reactome: R-HSA-77305;MetaCyc: PWY-7654;KEGG: 00281+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00627+4.2.1.17;Reactome: R-HSA-77310;MetaCyc: PWY-6945;MetaCyc: PWY-7656;KEGG: 00640+4.2.1.17;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77348;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-7778;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7216;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-5177;MetaCyc: PWY-7726;MetaCyc: PWY-7779;MetaCyc: PWY-6435;MetaCyc: PWY-6863;MetaCyc: PWY-7606;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7007;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-6583;Reactome: R-HSA-77346;KEGG: 00592+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77288;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;MetaCyc: PWY-5109	"Toluene degradation";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Geraniol degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Aminobenzoate degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Spodoptera littoralis pheromone biosynthesis";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid salvage";"Fatty acid degradation";"Caprolactam degradation";"Acyl chain remodeling of CL";"Tryptophan metabolism";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Geraniol degradation";"Fatty acid degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"beta-Alanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Phenylalanine metabolism";"Androstenedione degradation";"2-methylpropene degradation";"Benzoate degradation";"Butanoate metabolism";"Fatty acid elongation";"Limonene and pinene degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Fatty acid elongation";"Glutaryl-coa degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl tert-butyl ether degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to hexanol (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"alpha-Linolenic acid metabolism";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Butanoate metabolism";"Caprolactam degradation";"Lysine degradation";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Benzoate degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Carbon fixation pathways in prokaryotes";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fermentation to 2-methylbutanoate"
XP_054002811.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054013342.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054006583.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054008421.1	12	Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483	"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Macroautophagy";"Human cytomegalovirus infection";"Thermogenesis";"Activation of AMPK downstream of NMDARs"
XP_054013921.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_054001228.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054011677.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054001679.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_054015101.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054003170.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054008362.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-201688	"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Receptor Mediated Mitophagy";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL"
XP_054003454.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053996061.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053998882.1	4	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism"
XP_053997736.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_054015626.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_054005736.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054004499.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_054005896.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054013205.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054001227.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_054011678.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054015473.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_053996720.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053997541.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053997190.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054015424.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054010480.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054005190.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053996188.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054005290.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053999298.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053997290.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_053996451.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054003890.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054008204.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling"
XP_054013303.1	12	MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7857;MetaCyc: PWY-7118;MetaCyc: PWY-5133;KEGG: 00680+6.2.1.1	"Cis-genanyl-coa degradation";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Chitin degradation to ethanol";"Colupulone and cohumulone biosynthesis";"Methane metabolism"
XP_054005276.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054003730.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054008104.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_054007413.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053996326.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-196299;KEGG: 04714+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-198323;Reactome: R-HSA-5467340;Reactome: R-HSA-5250924;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5467348;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358747;Reactome: R-HSA-5610783;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4641262;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5358751;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358752;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716	"Regulation of HSF1-mediated heat shock response";"Beta-catenin phosphorylation cascade";"Thermogenesis";"Ubiquitin-dependent degradation of Cyclin D";"AKT phosphorylates targets in the cytosol";"AXIN missense mutants destabilize the destruction complex";"B-WICH complex positively regulates rRNA expression";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Truncations of AMER1 destabilize the destruction complex";"Human papillomavirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"Relaxin signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"S45 mutants of beta-catenin aren't phosphorylated";"Human immunodeficiency virus 1 infection";"T41 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin"
XP_054008434.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054013934.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054004309.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054011514.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054005176.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053999893.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053999795.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054007164.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053995570.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054006992.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559	"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway"
XP_054012246.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_054016004.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_053999733.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_054000187.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054010189.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_053995264.1	5	Reactome: R-HSA-165159;Reactome: R-HSA-198323;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5674400	"mTOR signalling";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_054007264.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054001462.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_054013986.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_054008486.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054012146.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054009077.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054001294.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054011253.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054012571.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054014805.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054013016.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054008978.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_054001942.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053999131.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054004330.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054006144.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054009012.1	4	Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_054004870.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054001456.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998589.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_054013685.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054013707.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053999231.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054010476.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054010018.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054014855.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053998172.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054016445.1	5	Reactome: R-HSA-3134975;Reactome: R-HSA-3249367;Reactome: R-HSA-1834941;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695	"Regulation of innate immune responses to cytosolic DNA";"STAT6-mediated induction of chemokines";"STING mediated induction of host immune responses";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation"
XP_054016817.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054001236.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_054004834.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054008628.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"Neutrophil degranulation";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_054000391.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054001406.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604	"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling"
XP_054002056.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054013329.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_054013757.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053999288.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_053997728.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011433.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375280	"G alpha (q) signalling events";"Amine ligand-binding receptors"
XP_054012932.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054005280.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054006035.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054015358.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_054015638.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_054010572.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054002664.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_053998961.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_054016054.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054006093.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054014251.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053996877.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_053996337.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054000173.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054013633.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1"
XP_054013353.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053998311.1	3	MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664	"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K"
XP_053996131.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_054013695.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053995586.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053997821.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054003774.1	4	MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_054007586.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054016315.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_054008154.1	7	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)"
XP_054004727.1	7	MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702	"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I"
XP_054014357.1	5	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_054004639.1	5	MetaCyc: PWY-6906;MetaCyc: PWY-6855;Reactome: R-HSA-70171;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_054005901.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053996231.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054006578.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054007482.1	83	Reactome: R-HSA-5654719;Reactome: R-HSA-5655291;Reactome: R-HSA-180336;Reactome: R-HSA-8851805;Reactome: R-HSA-5654732;Reactome: R-HSA-5655302;Reactome: R-HSA-8856825;Reactome: R-HSA-1257604;Reactome: R-HSA-5654710;Reactome: R-HSA-8983432;Reactome: R-HSA-5654689;Reactome: R-HSA-9028335;Reactome: R-HSA-210993;Reactome: R-HSA-6807004;Reactome: R-HSA-109704;Reactome: R-HSA-5654712;Reactome: R-HSA-8875360;Reactome: R-HSA-112412;Reactome: R-HSA-354194;Reactome: R-HSA-912631;Reactome: R-HSA-5637810;Reactome: R-HSA-8853338;Reactome: R-HSA-180292;Reactome: R-HSA-182971;Reactome: R-HSA-2730905;Reactome: R-HSA-9028731;Reactome: R-HSA-2179392;Reactome: R-HSA-5654733;Reactome: R-HSA-912526;Reactome: R-HSA-391160;Reactome: R-HSA-1433557;Reactome: R-HSA-2871809;Reactome: R-HSA-9607240;Reactome: R-HSA-1963640;Reactome: R-HSA-983695;Reactome: R-HSA-1433559;Reactome: R-HSA-6811558;Reactome: R-HSA-1236382;Reactome: R-HSA-1963642;Reactome: R-HSA-8851907;Reactome: R-HSA-9634285;Reactome: R-HSA-74751;Reactome: R-HSA-186763;Reactome: R-HSA-9664565;Reactome: R-HSA-8875656;Reactome: R-HSA-512988;Reactome: R-HSA-2424491;Reactome: R-HSA-8856828;Reactome: R-HSA-8865999;Reactome: R-HSA-5654704;Reactome: R-HSA-8875555;Reactome: R-HSA-5654688;Reactome: R-HSA-5663213;Reactome: R-HSA-1250196;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-2029482;Reactome: R-HSA-2428933;Reactome: R-HSA-5654726;Reactome: R-HSA-5654695;Reactome: R-HSA-167044;Reactome: R-HSA-9034864;Reactome: R-HSA-389359;Reactome: R-HSA-5654699;Reactome: R-HSA-5654720;Reactome: R-HSA-179812;Reactome: R-HSA-375165;Reactome: R-HSA-5655253;Reactome: R-HSA-1250347;Reactome: R-HSA-1839117;Reactome: R-HSA-9027284;Reactome: R-HSA-8853659;Reactome: R-HSA-74749;Reactome: R-HSA-2871796;Reactome: R-HSA-9645135;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-1295596;Reactome: R-HSA-9026519;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-8853334	"SHC-mediated cascade:FGFR4";"Signaling by FGFR4 in disease";"SHC1 events in EGFR signaling";"MET activates RAS signaling";"Negative regulation of FGFR3 signaling";"Signaling by FGFR1 in disease";"Cargo recognition for clathrin-mediated endocytosis";"PIP3 activates AKT signaling";"PI-3K cascade:FGFR3";"Interleukin-15 signaling";"PI-3K cascade:FGFR1";"Activated NTRK2 signals through PI3K";"Tie2 Signaling";"Negative regulation of MET activity";"PI3K Cascade";"FRS-mediated FGFR4 signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"SOS-mediated signalling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Regulation of signaling by CBL";"Constitutive Signaling by EGFRvIII";"Signaling by FGFR3 point mutants in cancer";"GAB1 signalosome";"EGFR downregulation";"Role of LAT2/NTAL/LAB on calcium mobilization";"Activated NTRK2 signals through FRS2 and FRS3";"EGFR Transactivation by Gastrin";"Negative regulation of FGFR4 signaling";"Interleukin receptor SHC signaling";"Signal regulatory protein family interactions";"Signaling by SCF-KIT";"FCERI mediated Ca+2 mobilization";"FLT3 Signaling";"GRB2 events in ERBB2 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of KIT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"PI3K events in ERBB2 signaling";"MET activates PI3K/AKT signaling";"Constitutive Signaling by Overexpressed ERBB2";"Insulin receptor signalling cascade";"Downstream signal transduction";"Signaling by ERBB2 KD Mutants";"MET receptor recycling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"DAP12 signaling";"Clathrin-mediated endocytosis";"MET activates PTPN11";"SHC-mediated cascade:FGFR3";"MET activates RAP1 and RAC1";"SHC-mediated cascade:FGFR1";"RHO GTPases Activate WASPs and WAVEs";"SHC1 events in ERBB2 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"Regulation of actin dynamics for phagocytic cup formation";"SHC-related events triggered by IGF1R";"Negative regulation of FGFR1 signaling";"PI-3K cascade:FGFR2";"Signalling to RAS";"Activated NTRK3 signals through RAS";"CD28 dependent Vav1 pathway";"SHC-mediated cascade:FGFR2";"PI-3K cascade:FGFR4";"GRB2 events in EGFR signaling";"NCAM signaling for neurite out-growth";"Signaling by FGFR2 in disease";"SHC1 events in ERBB4 signaling";"Signaling by cytosolic FGFR1 fusion mutants";"Erythropoietin activates RAS";"RET signaling";"Signal attenuation";"FCERI mediated MAPK activation";"STAT5 Activation";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Spry regulation of FGF signaling";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"Signaling by FGFR3 fusions in cancer"
XP_054001284.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054009992.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors"
XP_054002382.1	11	Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-877312;Reactome: R-HSA-388841;Reactome: R-HSA-9008059;Reactome: R-HSA-391160;Reactome: R-HSA-512988;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-114604;Reactome: R-HSA-210990	"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"Regulation of IFNG signaling";"Costimulation by the CD28 family";"Interleukin-37 signaling";"Signal regulatory protein family interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PD-1 signaling";"Platelet sensitization by LDL";"GPVI-mediated activation cascade";"PECAM1 interactions"
XP_054012616.1	6	KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation"
XP_053996375.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054013996.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054008496.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-112382	"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex"
XP_054011928.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing"
XP_054000658.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_053999607.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054003606.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053999785.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053998260.1	3	KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_054014735.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054000426.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_054014833.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054003985.1	9	MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7902;Reactome: R-HSA-1483166	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"Synthesis of PA"
XP_054014793.1	10	Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508	"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_054005981.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_053998574.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_054002096.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054003379.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054013837.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054002070.1	3	KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999	"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle"
XP_054011455.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054005239.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054003686.1	16	Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_054016094.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_053997239.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053999687.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054001434.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054007232.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054010223.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_053999705.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054013312.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054002841.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053998618.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_054007402.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054010174.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053996258.1	13	KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;Reactome: R-HSA-1855204	"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol"
XP_053999974.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054002302.1	7	MetaCyc: PWY-7782;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7818;MetaCyc: PWY-7886;Reactome: R-HSA-1483213	"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PC";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE"
XP_054003015.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;Reactome: R-HSA-983168	"Protein ubiquitination";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054010560.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053995402.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_054011888.1	3	Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_054005139.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054015407.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_054014291.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_053996697.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053997011.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053995215.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054013773.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_054003634.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054003800.1	6	KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-5097;KEGG: 00261+4.3.3.7;MetaCyc: PWY-8088;MetaCyc: PWY-2942	"Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis VI";"Monobactam biosynthesis";"Dipicolinate biosynthesis";"L-lysine biosynthesis III"
XP_054003354.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054015871.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054009542.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-420092;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-381676	"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"Glucagon-type ligand receptors";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_054007115.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054004399.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054012810.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054016613.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054011781.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054013546.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054014777.1	8	KEGG: 00521+5.5.1.4;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6664;MetaCyc: PWY-6372;MetaCyc: PWY-6580;MetaCyc: PWY-2301;Reactome: R-HSA-1855183	"Streptomycin biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol biosynthesis I (bacteria)";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054010159.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_054010908.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053997100.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053996755.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_054013271.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054007811.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054005200.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053995811.1	4	Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9	"Peroxisomal protein import";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism"
XP_054016027.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054006029.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054015275.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053997150.1	4	Reactome: R-HSA-4720454;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261	"Defective ALG9 causes ALG9-CDG (CDG-1l)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_054005423.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054000107.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_054005150.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054010958.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054011738.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054001279.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053999158.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053997474.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054005474.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053998248.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053997250.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053999829.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054009822.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes"
XP_054002916.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053999697.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054010047.1	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610787	"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Hedgehog 'off' state"
XP_054011112.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054013063.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054016848.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054015601.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054014568.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054014067.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_053997991.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054004069.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_054005991.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_054014885.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054014783.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054015126.1	14	MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-5667	"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I"
XP_054010548.1	17	Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5357956;Reactome: R-HSA-975163;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-9014325;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-4086398;Reactome: R-HSA-9645460	"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ca2+ pathway";"Alpha-protein kinase 1 signaling pathway"
XP_054016741.1	3	MetaCyc: PWY-1801;KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590	"Formaldehyde oxidation II (glutathione-dependent)";"Methane metabolism";"Glutathione conjugation"
XP_054002034.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053995946.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054012055.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053996438.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053999673.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054005569.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_054010130.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053995452.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5080;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724	"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_054007452.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053997459.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054006446.1	18	MetaCyc: PWY-7117;KEGG: 00250+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;MetaCyc: PWY-7383;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Alanine, aspartate and glutamate metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Tyrosine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine biosynthesis"
XP_054009029.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054007562.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_054011791.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054008184.1	9	Reactome: R-HSA-114604;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"GPVI-mediated activation cascade";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"NRAGE signals death through JNK";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_054003428.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719	"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors"
XP_054004389.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054006966.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054011831.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_054014387.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054011371.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054007466.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_054006542.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053998530.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978	"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_054016036.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054004975.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054016243.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054001496.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_053995556.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054000301.1	5	MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7	"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism"
XP_054007556.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_054003430.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692	"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity"
XP_054014838.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_054009661.1	7	Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-201681;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262	"WNT mediated activation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_053998027.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_054014378.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359	"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation"
XP_054013275.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053998528.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_054007447.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054004484.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053995815.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054012110.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054008060.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_054003200.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054000857.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054015724.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490	"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation"
XP_054007967.1	5	Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00330+1.14.13.39	"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine and proline metabolism"
XP_054015393.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053995211.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054010859.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998613.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054013871.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_054013040.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_054015962.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054006058.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054015875.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054015546.1	9	KEGG: 00020+6.4.1.1;KEGG: 00720+6.4.1.1;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-6146;MetaCyc: PWY-8086;Reactome: R-HSA-70263	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis"
XP_054005920.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054000984.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054016559.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054006557.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism"
XP_054011785.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054006467.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054004515.1	5	KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403	"Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Glutathione metabolism";"Glutathione synthesis and recycling"
XP_054008827.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_054011451.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184	"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_054014133.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054003239.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_054013237.1	3	Reactome: R-HSA-168928;Reactome: R-HSA-9639288;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amino acids regulate mTORC1";"Fructose catabolism"
XP_054012419.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_054003011.1	9	Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173788	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"Downregulation of TGF-beta receptor signaling"
XP_054003409.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837	"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases"
XP_054013407.1	5	Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
XP_054014046.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053998860.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054000936.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011326.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054003139.1	4	KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331	"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I"
XP_054013137.1	4	Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053996229.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_054016160.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_054010052.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054003981.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_054016574.1	15	KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5723;Reactome: R-HSA-70171	"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Rubisco shunt";"Glycolysis"
XP_054011720.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054001804.1	6	MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-196780	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism"
XP_054014731.1	8	MetaCyc: PWY-6142;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-5789	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_054005985.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_054002141.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion"
XP_053995792.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054009507.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-6798695	"Neddylation";"Neutrophil degranulation"
XP_053996485.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054015377.1	21	MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7205;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7219;MetaCyc: PWY-7198;MetaCyc: PWY-7222;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7176	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis"
XP_054010654.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053996129.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133	"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1"
XP_053997799.1	5	KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;Reactome: R-HSA-389661	"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation"
XP_054002241.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054006122.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054001973.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054001762.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_054015797.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_054008786.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_054010823.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054004436.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054000355.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_054004256.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053998036.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054001854.1	9	Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTORC1-mediated signalling";"Macroautophagy";"Neutrophil degranulation";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes"
XP_054011795.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054002525.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054001674.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054010953.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011835.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053999153.1	20	KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7606	"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_054011733.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054008547.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport"
XP_054011375.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054007050.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054001072.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054001987.1	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5972	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)"
XP_054010370.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054015383.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_054010790.1	7	MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation"
XP_054012640.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054011401.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_054009947.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054014120.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054004494.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053998364.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054000471.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054008957.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_054010543.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054003938.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054003569.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-180585;Reactome: R-HSA-8951664	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Vif-mediated degradation of APOBEC3G";"Neddylation"
XP_054014220.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_054001706.1	12	Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-205043	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus"
XP_054011231.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053999229.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053997789.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053996433.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054000807.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054005850.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054005304.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism"
XP_054008796.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054008376.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053996103.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054008836.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_054011198.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053999485.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053997995.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054011877.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_053999129.1	30	Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8941332;Reactome: R-HSA-389357;Reactome: R-HSA-198693;Reactome: R-HSA-199418;Reactome: R-HSA-1257604;Reactome: R-HSA-69656;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-211163;Reactome: R-HSA-8876198;Reactome: R-HSA-111447;Reactome: R-HSA-389513;Reactome: R-HSA-8948751;Reactome: R-HSA-5628897;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-392451;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-9634638;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804759;Reactome: R-HSA-9614399;Reactome: R-HSA-198323;Reactome: R-HSA-6804757	"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"RUNX2 regulates genes involved in cell migration";"CD28 dependent PI3K/Akt signaling";"AKT phosphorylates targets in the nucleus";"Negative regulation of the PI3K/AKT network";"PIP3 activates AKT signaling";"Cyclin A:Cdk2-associated events at S phase entry";"mTOR signaling pathway";"Cyclin E associated events during G1/S transition";"AKT-mediated inactivation of FOXO1A";"RAB GEFs exchange GTP for GDP on RABs";"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"Regulation of PTEN stability and activity";"TP53 Regulates Metabolic Genes";"Relaxin signaling pathway";"Human papillomavirus infection";"Downregulation of ERBB2:ERBB3 signaling";"G beta:gamma signalling through PI3Kgamma";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Acetylation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Thermogenesis";"Regulation of TP53 Activity through Association with Co-factors";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the cytosol";"Regulation of TP53 Degradation"
XP_054000927.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054014881.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054005995.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054002580.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053997933.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054014285.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_054003423.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_054004427.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054008770.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_054008390.1	2	KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_054016248.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054010993.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054001734.1	10	MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587	"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)"
XP_054014801.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054012575.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054004045.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053995864.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054006587.1	6	MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497	"Guanosine nucleotides degradation II";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)"
XP_054010362.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054004296.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_054015478.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054011755.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054001060.1	14	MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_054013681.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054000887.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054000320.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_054005384.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054011022.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053997709.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054000065.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-879415	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling"
XP_053999293.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054007702.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053999235.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_054009597.1	9	Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173789	"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_054008609.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_054004454.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_054014493.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_054006844.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054013308.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053998602.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054010636.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_054000726.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_054004170.1	9	MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00480+2.5.1.18	"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Glutathione metabolism"
XP_054007418.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054004270.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054015986.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054008997.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053999277.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053999738.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054001907.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054015620.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_054005064.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053997890.1	16	Reactome: R-HSA-196025;Reactome: R-HSA-164939;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-2132295;Reactome: R-HSA-8856825;Reactome: R-HSA-437239;Reactome: R-HSA-8856828	"Formation of annular gap junctions";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Retrograde neurotrophin signalling";"LDL clearance";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"MHC class II antigen presentation";"Cargo recognition for clathrin-mediated endocytosis";"Recycling pathway of L1";"Clathrin-mediated endocytosis"
XP_053997064.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053996565.1	15	Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586	"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence"
XP_054015303.1	10	KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-7385;MetaCyc: PWY-5484	"Methane metabolism";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)"
XP_054000979.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054009746.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054010082.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054011829.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_054002968.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054012537.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053997955.1	20	Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210	"Polymerase switching";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054005545.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_054008924.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053996044.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054009031.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054001786.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054007348.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054008762.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-141444	"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054002448.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054008630.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_054008804.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II"
XP_054008350.1	5	MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation"
XP_054014477.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054005336.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053997336.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054006649.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054009219.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_054003489.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054008072.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade"
XP_054008987.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054004328.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053996371.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053997121.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472	"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054008674.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_053997221.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053999781.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012081.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_054011549.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054008623.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053998315.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053997774.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053996193.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Neddylation"
XP_054009587.1	7	KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5466	"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis"
XP_054000897.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054005394.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation"
XP_054015633.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053996135.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053997723.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053999283.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_054003901.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_054004286.1	22	KEGG: 00520+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-8013;MetaCyc: PWY-7385;MetaCyc: PWY-5659;MetaCyc: PWY-6142;Reactome: R-HSA-6798695;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5514;MetaCyc: PWY-621;MetaCyc: PWY-5054;MetaCyc: PWY-7238;MetaCyc: PWY-7347;MetaCyc: PWY-6992;Reactome: R-HSA-70171;KEGG: 00500+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-3801;Reactome: R-HSA-70263;MetaCyc: PWY-622;MetaCyc: PWY-5384;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"TP53 Regulates Metabolic Genes";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"GDP-mannose biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation III (sucrose invertase)";"D-sorbitol biosynthesis I";"Sucrose biosynthesis II";"Sucrose biosynthesis III";"1,5-anhydrofructose degradation";"Glycolysis";"Starch and sucrose metabolism";"Pentose phosphate pathway";"Sucrose degradation II (sucrose synthase)";"Gluconeogenesis";"Starch biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"Chitin biosynthesis"
XP_054001884.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053996293.1	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
XP_054005905.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054010983.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053996235.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054004404.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054008339.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054012744.1	8	KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27	"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Propanoate metabolism"
XP_053999044.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053996112.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054006119.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054013638.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053998332.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054006340.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes"
XP_053998965.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054001836.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_054003180.1	5	Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3	"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism"
XP_054009649.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_054001770.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054014851.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_054007360.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054002550.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054006573.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053999565.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054011803.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_054011974.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053997759.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054015757.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_054000824.1	9	Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)"
XP_054010700.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054005759.1	16	Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-9009391;Reactome: R-HSA-512988;Reactome: R-HSA-912526;Reactome: R-HSA-1257604;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558	"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Extra-nuclear estrogen signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin receptor SHC signaling";"PIP3 activates AKT signaling";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"RET signaling";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Costimulation by the CD28 family";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_053995752.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054010694.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_054016172.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054000333.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054011301.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_054014695.1	6	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-8874081	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen degradation";"MET activates PTK2 signaling"
XP_054010496.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053999544.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_054006531.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053998192.1	8	MetaCyc: PWY-7193;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;Reactome: R-HSA-73614;Reactome: R-HSA-6798695;MetaCyc: PWY-7199	"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage"
XP_054004825.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_054014353.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054004394.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054003639.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054005286.1	8	MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-191273	"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis"
XP_054013729.1	12	MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00561+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7817;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9	"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycerolipid metabolism";"Formation of the active cofactor, UDP-glucuronate";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_054012026.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053998464.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519	"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression"
XP_054014970.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054000791.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054004905.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_053998292.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_054011842.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_054006024.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054001400.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053998944.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053995525.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_054002050.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054015758.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_054003886.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054000293.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053999065.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054010254.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_054006073.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054010154.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054000193.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_053996629.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054001230.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054000405.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-2151201	"UCH proteinases";"HATs acetylate histones";"Transcriptional activation of mitochondrial biogenesis"
XP_054004221.1	5	Reactome: R-HSA-5205685;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-983168;Reactome: R-HSA-5689877	"Pink/Parkin Mediated Mitophagy";"Aggrephagy";"Amyloid fiber formation";"Antigen processing: Ubiquitination & Proteasome degradation";"Josephin domain DUBs"
XP_054003374.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5987;MetaCyc: PWY-5996	"Fatty acyl-CoA biosynthesis";"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_054003600.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054008572.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-442982	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_054003834.1	3	Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3	"Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism"
XP_054000212.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053998711.1	4	Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871	"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane"
XP_054008988.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054016715.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_054012610.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_054000112.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_054001047.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_054008490.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1"
XP_054013990.1	5	MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_053996873.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054006598.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination"
XP_053996333.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-983231;Reactome: R-HSA-5610787	"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state"
XP_053996653.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054015155.1	3	MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_053999979.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053997134.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
XP_054013151.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054001439.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054000898.1	11	MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-6545	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III"
XP_053995580.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054009588.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis"
XP_054001109.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054007580.1	24	Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-418597	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events"
XP_054000738.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053997234.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_054001958.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_054010628.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053997454.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_054002211.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054008931.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054012538.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_054005564.1	7	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_054015435.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053996065.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054009622.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053999737.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054001908.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472	"Regulation of PTEN gene transcription";"HCMV Early Events";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054011157.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053999278.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_054013201.1	8	MetaCyc: PWY-7573;KEGG: 00520+4.2.1.47;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-5739;MetaCyc: PWY-5740;Reactome: R-HSA-6787639	"GDP-mycosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-fucose biosynthesis"
XP_054003736.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054016369.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054014986.1	5	MetaCyc: PWY-5523;MetaCyc: PWY-6168;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26;MetaCyc: PWY-7863	"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Flavin biosynthesis III (fungi)";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism";"Roseoflavin biosynthesis"
XP_054015801.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_054000781.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_054005045.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054014478.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053997296.1	4	MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_054004384.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053998182.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054004709.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858	"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"RMTs methylate histone arginines"
XP_054015921.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054002447.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_054002815.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054008189.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054004545.1	26	Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-9619483	"Separation of Sister Chromatids";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"Gap junction assembly";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs"
XP_053999775.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054001123.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053999653.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054007141.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053996979.1	3	KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963;Reactome: R-HSA-947581	"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_054001174.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054010204.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054001223.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_054013010.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054002792.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_053996385.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054002832.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054004656.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-881907;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors"
XP_054006588.1	6	MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6606;KEGG: 00230+3.5.4.3	"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Purine metabolism"
XP_054002372.1	3	MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_054007472.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_054008998.1	15	Reactome: R-HSA-5467333;Reactome: R-HSA-5467340;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5358751;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5358749	"APC truncation mutants are not K63 polyubiquitinated";"AXIN missense mutants destabilize the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"S45 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated"
XP_054014620.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_054008480.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054011351.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_054004730.1	3	Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198	"Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis"
XP_054004064.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054007417.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053995845.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-69656;Reactome: R-HSA-1362277	"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex"
XP_054014303.1	10	Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2	"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Stachyose degradation";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism"
XP_054006917.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_053995576.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054014934.1	19	MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380320;MetaCyc: PWY-7221;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7184	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Recruitment of NuMA to mitotic centrosomes";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_054007576.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054013307.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054015563.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_054005262.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053999984.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054006716.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054015120.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;MetaCyc: PWY-7782;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_054000928.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054011878.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054007269.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695	"Cutin, suberine and wax biosynthesis";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation"
XP_053997162.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054003676.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054000808.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054007169.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054005256.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I"
XP_054003704.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_054016247.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053999612.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053998584.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054004428.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054006149.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_054005971.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_054005156.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054014383.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054008130.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_054003975.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-735	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis"
XP_054016030.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_054001490.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053995550.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053999693.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054007550.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_054015429.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054001572.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054000495.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053997427.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_054008548.1	4	Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport"
XP_054000103.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054011273.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_054011224.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054014063.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_054014787.1	10	Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_054012461.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054011519.1	11	Reactome: R-HSA-191273;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7560;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7524;MetaCyc: PWY-6174;MetaCyc: PWY-922	"Cholesterol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I"
XP_054004850.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism"
XP_054004304.1	18	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination"
XP_054001517.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_054003937.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054008109.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054013458.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_054008958.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053998432.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054010406.1	52	Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-1834949;Reactome: R-HSA-203927;Reactome: R-HSA-167152;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167242;Reactome: R-HSA-73863;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-73772;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-76071	"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"Cytosolic sensors of pathogen-associated DNA";"MicroRNA (miRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054011391.1	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531;MetaCyc: PWY-7766;Reactome: R-HSA-189451;MetaCyc: PWY-7159	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_054014605.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054009814.1	19	KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;Reactome: R-HSA-70263;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-1622	"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Reductive TCA cycle II";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)"
XP_054007940.1	12	Reactome: R-HSA-194840;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Rho GTPase cycle";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_053998202.1	22	MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5353;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-7727	"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)"
XP_054015881.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054001476.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054003069.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_054013885.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_054013138.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053998152.1	4	Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_054014724.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054010566.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054014962.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054014335.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054014773.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_054003680.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053998594.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_054000751.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054010321.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054004032.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053998252.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053999142.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054008828.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054002090.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054015798.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_054016074.1	10	Reactome: R-HSA-69205;MetaCyc: PWY-7198;MetaCyc: PWY-7199;Reactome: R-HSA-499943;MetaCyc: PWY-3841;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7210	"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleosides salvage";"Interconversion of nucleotide di- and triphosphates";"Folate transformations II (plants)";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_054010294.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053998166.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054002864.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054016023.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_054015378.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_054014171.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_054009508.1	13	Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-8866427;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"MHC class II antigen presentation";"VLDLR internalisation and degradation";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_054010194.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_054016672.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054016852.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054002702.1	8	KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1	"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism"
XP_053997206.1	13	Reactome: R-HSA-1660662;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52	"Glycosphingolipid metabolism";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation"
XP_053997621.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_053998527.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054015891.1	4	KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517	"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II"
XP_054013833.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion"
XP_054008123.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2"
XP_054014837.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_053997106.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054006948.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054004839.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054008174.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054006468.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054014312.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_054015133.1	7	MetaCyc: PWY-4984;Reactome: R-HSA-70635;KEGG: 00220+3.5.3.1;MetaCyc: PWY-6922;MetaCyc: PWY-46;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31	"Urea cycle";"Urea cycle";"Arginine biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Arginine and proline metabolism";"Canavanine degradation"
XP_054006558.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054000485.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054013540.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054015403.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394	"UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER"
XP_054011608.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054001480.1	10	KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-2160916;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096	"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Other glycan degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Hyaluronan uptake and degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"HS-GAG degradation"
XP_054015046.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_054008721.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053997532.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_054016059.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054003806.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053995968.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054015295.1	14	MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453	"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Synthesis of PC";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Ether lipid metabolism";"Stigma estolide biosynthesis"
XP_054000858.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054012675.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054016770.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054002794.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_054002323.1	40	Reactome: R-HSA-6782135;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-5578749;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6803529	"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcriptional regulation by small RNAs";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing"
XP_054012855.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054009158.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054007474.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_054010102.1	26	Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-2467813	"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Gap junction assembly";"MHC class II antigen presentation";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Separation of Sister Chromatids"
XP_054001441.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054002834.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054012488.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054011746.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_053999822.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053998043.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054004056.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054011031.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054012151.1	7	Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110362;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394	"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER"
XP_054013168.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054010536.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011340.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_054001961.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_054016836.1	11	MetaCyc: PWY-7791;MetaCyc: PWY-5154;Reactome: R-HSA-500753;MetaCyc: PWY-5686;KEGG: 00240+3.5.2.3;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7790;KEGG: 00250+2.1.3.2;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7400	"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine biosynthesis";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"L-arginine biosynthesis IV (archaebacteria)"
XP_054009624.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054011098.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_054014915.1	6	MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_054015163.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_054007569.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_054006208.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054008843.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053997452.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054007938.1	12	Reactome: R-HSA-416482;Reactome: R-HSA-5655302;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117	"G alpha (12/13) signalling events";"Signaling by FGFR1 in disease";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants"
XP_054008745.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053996446.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054007459.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054015263.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-111469;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs"
XP_054012729.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054001599.1	57	Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556	"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport"
XP_054003050.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054016048.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054005645.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_054002886.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054013765.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053998184.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053997645.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054014616.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054000849.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_054003641.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053997466.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054014867.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis"
XP_054006549.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_054004869.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054003000.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409	"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_054016786.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054000114.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_054006481.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-381676	"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_054008574.1	9	Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001	"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade"
XP_054003832.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053998227.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054003792.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054005718.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054001647.1	3	KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615;Reactome: R-HSA-1474151	"Folate biosynthesis";"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_053997718.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053995239.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_054013319.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053999316.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_054013140.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-9603505	"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"NTRK3 as a dependence receptor"
XP_054006158.1	4	KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053997232.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_054012498.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054012980.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054007139.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054016827.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_054006829.1	56	Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway"
XP_053997132.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-110331	"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine"
XP_054002309.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054002784.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054008559.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053998462.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-6804114;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082	"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression"
XP_054010166.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054011844.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_053998294.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_053999966.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054012431.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054003967.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_054013538.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054003039.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053999542.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_054004963.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053998194.1	32	Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167160	"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_054009108.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054014571.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054012703.1	7	MetaCyc: PWY-6906;Reactome: R-HSA-71336;MetaCyc: PWY-8004;MetaCyc: PWY-5514;MetaCyc: PWY-6855;KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6	"Chitin derivatives degradation";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism"
XP_053999003.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_054004443.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053998566.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054006853.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053999665.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054016060.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054010152.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054012925.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054006022.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054005811.1	3	Reactome: R-HSA-373080;Reactome: R-HSA-4608870;Reactome: R-HSA-4086400	"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins";"PCP/CE pathway"
XP_054010252.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053996029.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_053998321.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054004006.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-176034	"Estrogen-dependent gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Interactions of Tat with host cellular proteins"
XP_054000553.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054013449.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054003815.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_054006812.1	4	KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_053998179.1	20	Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9639288;Reactome: R-HSA-389357;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920	"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Thermogenesis";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Amino acids regulate mTORC1";"CD28 dependent PI3K/Akt signaling";"Relaxin signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Macroautophagy";"mTOR signalling";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability"
XP_053996819.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_054003360.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054008172.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054001148.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_054009561.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053998628.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_054000512.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_053998279.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054012181.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054010213.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_054001248.1	8	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_054013551.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053997534.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054007280.1	33	Reactome: R-HSA-69202;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-674695;Reactome: R-HSA-69231;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-72086;Reactome: R-HSA-167158	"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Pre-transcription Events";"Cyclin D associated events in G1";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex"
XP_054009720.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_054008217.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_054013461.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_054006198.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054011507.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053999767.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054012067.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054001509.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_054012885.1	12	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"DCC mediated attractive signaling";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054006337.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_054012783.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_053999083.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_054001843.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053998254.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054008311.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-68884	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Mitotic Telophase/Cytokinesis"
XP_054006019.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053998592.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_054008599.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054006131.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054005586.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054014055.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"Intraflagellar transport"
XP_054007821.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054004632.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054000740.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054006231.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053999244.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_054016854.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054016300.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054003910.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing"
XP_054000346.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054016674.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054001530.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_054006835.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054002389.1	40	Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-5578749;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-167238	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation"
XP_054016623.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054006733.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128	"Mitotic Prometaphase";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling"
XP_054009999.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053998496.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_054004366.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054002975.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054000593.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054012900.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053995225.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_053996077.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade"
XP_053999035.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054003348.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054007541.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054016804.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054006720.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053999093.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053995190.1	6	Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_054012895.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054004096.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Gluconeogenesis"
XP_053995290.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human immunodeficiency virus 1 infection"
XP_054011122.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_054009298.1	4	Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741	"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054004070.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053999819.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054006561.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054012191.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054002806.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054004302.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054010643.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054003669.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_054001618.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054013667.1	11	MetaCyc: PWY-882;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-3861	"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Mannitol degradation II"
XP_053998434.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054005570.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053997164.1	15	Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693616	"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_054009795.1	22	Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262	"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_054012408.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_054012138.1	3	Reactome: R-HSA-8963684;Reactome: R-HSA-204174;Reactome: R-HSA-156590	"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation"
XP_053996363.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054016609.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_054009989.1	6	Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-416993	"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors"
XP_054006607.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_054014810.1	10	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_054000768.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053998486.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054001469.1	10	KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8051	"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I"
XP_054003418.1	19	Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244	"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation"
XP_054006883.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_054010182.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053999077.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_053999982.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053998978.1	7	KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053997343.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054009019.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054001949.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054003864.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_054005596.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_054008589.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054003702.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054009231.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_053998582.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053996244.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053999078.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_054012778.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053996165.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054005070.1	11	Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery"
XP_054003417.1	19	Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-399719	"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Trafficking of AMPA receptors"
XP_054003845.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053997070.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054000767.1	2	KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819	"Purine metabolism";"Vitamin B1 (thiamin) metabolism"
XP_054006608.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_054005302.1	5	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_054016480.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_054001059.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972	"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)"
XP_053996265.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054009224.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_054012407.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054003576.1	3	Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053997145.1	5	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_054002981.1	17	Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-3270619;Reactome: R-HSA-5685939;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5685938;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"IRF3-mediated induction of type I IFN";"HDR through MMEJ (alt-NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination"
XP_054005145.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054003472.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054005096.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_053997096.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054002100.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054013210.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_054002430.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114	"G1/S-Specific Transcription";"Cyclin D associated events in G1";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest"
XP_053999593.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211	"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes"
XP_053995870.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662	"Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism"
XP_054007330.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054001672.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054010004.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054003347.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053998421.1	6	MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;Reactome: R-HSA-977347;KEGG: 00260+2.6.1.52;KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Methane metabolism"
XP_054012040.1	3	Reactome: R-HSA-425561;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Sodium/Calcium exchangers";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054004570.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_054004164.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054013668.1	11	MetaCyc: PWY-882;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-6992	"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation"
XP_054011619.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053998935.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054008369.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_054006061.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582	"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)"
XP_053998993.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_054015810.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_054007896.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_054014465.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_054014555.1	3	KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471	"Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB"
XP_053996512.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054011440.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054015314.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054003611.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054005615.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054012126.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053997615.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_054010965.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054002423.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053996078.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_054010332.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_054010652.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054007794.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054001764.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_054007374.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_053995600.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758	"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation"
XP_054008715.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054001802.1	6	KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987	"Biotin metabolism";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_054002250.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054010054.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054000093.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_053999265.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300	"DNA methylation";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA"
XP_054011960.1	7	KEGG: 00310+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00020+2.3.1.61	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Citrate cycle (TCA cycle)"
XP_054000035.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472	"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054005916.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_053996740.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053997521.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_054007886.1	5	KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7177;MetaCyc: PWY-7176	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis"
XP_054001247.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_054005521.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053995886.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_054011249.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system"
XP_054008892.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053998627.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_054000012.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054005366.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054001147.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_054005034.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_054000982.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054010079.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054006338.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes"
XP_054004586.1	10	Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-5628897;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-611105;Reactome: R-HSA-111464	"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"TP53 Regulates Metabolic Genes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Respiratory electron transport";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_053997760.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011716.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053996593.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054005760.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557	"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"RET signaling";"Signaling by SCF-KIT"
XP_054011508.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053999768.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054012068.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054016199.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054008218.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24	"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway"
XP_054005352.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999583.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_054007727.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054008059.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_054011161.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054014595.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053998725.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054013537.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681	"Hedgehog 'on' state";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions"
XP_053999042.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_054011261.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054007806.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_054004402.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054005313.1	56	Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276	"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_053998334.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_053998874.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_053997313.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054011865.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054016450.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999503.1	3	MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831	"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide"
XP_053995625.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054011972.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054011087.1	8	MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7922	"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_054012473.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053998066.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054012424.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054009207.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_054014840.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054002190.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053995754.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054000902.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_054010860.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011588.1	13	Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724	"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription"
XP_054002290.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054016274.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_053997717.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053998228.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053998859.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054008074.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072	"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_054004811.1	12	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-1169408;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72662	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"ISG15 antiviral mechanism";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_054012510.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-202433	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Generation of second messenger molecules"
XP_054012681.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053997006.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054009842.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase"
XP_054000029.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054015095.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism"
XP_054006698.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053996553.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054015033.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053996463.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054009475.1	18	MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922	"Plasmalogen degradation";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI"
XP_054016828.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_054015246.1	17	KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6627;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6609;MetaCyc: PWY-6611;MetaCyc: PWY-4202	"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Purine salvage";"Pyrimidine metabolism";"Neutrophil degranulation";"Guanine and guanosine salvage";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage III";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)"
XP_054006257.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054005772.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_054007399.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012497.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053997772.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054005963.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_054002499.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054006157.1	4	KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054016159.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433	"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation"
XP_053995511.1	18	KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051	"Ether lipid metabolism";"Acyl chain remodelling of PI";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_054011367.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054011598.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054002280.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054006207.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053997664.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_054010682.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-264876	"Intra-Golgi traffic";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Insulin processing"
XP_054002180.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054007069.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053999529.1	19	Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-975634;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828	"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Retinoid metabolism and transport";"LDL remodeling";"Chylomicron assembly";"Scavenging by Class H Receptors";"LDL clearance";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"VLDL assembly";"Chylomicron remodeling";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Clathrin-mediated endocytosis"
XP_053997062.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054016109.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-167590	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation"
XP_054001099.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_054006107.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054011097.1	3	KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693	"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism"
XP_054005062.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054016548.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054000710.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054014868.1	4	KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
XP_054008802.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053999214.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053996644.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_054010914.1	12	KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783	"Arachidonic acid metabolism";"Linoleic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Plasmalogen degradation"
XP_054008030.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054008922.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_054013422.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053998929.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054001715.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054009426.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053995690.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053997382.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_054004645.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_054007690.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054005382.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054016400.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054006475.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-1489509	"Ion homeostasis";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling"
XP_053998396.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054001660.1	56	Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556	"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport"
XP_054009257.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_054007704.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054012487.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054008247.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053995862.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054013081.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054007975.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_054001732.1	10	MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453	"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis"
XP_054007862.1	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
XP_054006688.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053998543.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054010741.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response"
XP_054015085.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-6804757;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-6803204;Reactome: R-HSA-349425;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;KEGG: 05170+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803207	"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Thermogenesis";"Regulation of TP53 Activity through Methylation";"Regulation of TP53 Degradation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Stabilization of p53";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Autodegradation of the E3 ubiquitin ligase COP1";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"Human immunodeficiency virus 1 infection";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"mTOR signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_054001892.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_054003269.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054013267.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054008411.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053998002.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054000966.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054004452.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380284	"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053995856.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_054003169.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis"
XP_053998604.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053998830.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_053998051.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054014706.1	9	MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;KEGG: 00010+1.2.1.12;KEGG: 00710+1.2.1.12;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis"
XP_054001220.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_054001788.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054011162.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053997338.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054006760.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054005658.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_054005338.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054016055.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054004401.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054011262.1	19	Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-8950505;Reactome: R-HSA-114604	"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"EGFR downregulation";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade"
XP_053999041.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_054003897.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054011156.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054012243.1	24	Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;Reactome: R-HSA-5607764;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-444257;Reactome: R-HSA-2871837;Reactome: R-HSA-6804757;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;KEGG: 04714+2.7.11.1	"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"RSK activation";"FCERI mediated NF-kB activation";"Regulation of TP53 Degradation";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Thermogenesis"
XP_054000821.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054003629.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054003278.1	19	Reactome: R-HSA-8957275;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Post-translational protein phosphorylation";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Scavenging by Class H Receptors";"LDL clearance";"LDL remodeling";"Chylomicron assembly";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"VLDL clearance";"Chylomicron remodeling";"VLDL assembly";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054013739.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054013627.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6922	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis"
XP_054014987.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-7863	"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis"
XP_054016444.1	3	Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3108214	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins"
XP_054004835.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053996886.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054014854.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription"
XP_054012143.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_054006916.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_053999784.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054010638.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054013306.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_054015572.1	24	Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2132295	"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Separation of Sister Chromatids";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Cilium Assembly";"MHC class II antigen presentation"
XP_054009841.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_053996374.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054012682.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054004812.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704	"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade"
XP_054007416.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054009070.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054001285.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054013092.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_054004298.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_054015018.1	6	Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110357	"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"Displacement of DNA glycosylase by APEX1"
XP_054014659.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054014879.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744	"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_054008155.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-983168	"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054016314.1	17	Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_054009096.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_054013694.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997391.1	9	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_054003775.1	4	MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_053997771.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054003824.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_054005771.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_054013362.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008105.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_054012613.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054014609.1	18	Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783	"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Plasmalogen degradation"
XP_054013993.1	14	Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression"
XP_053997061.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054003603.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054003065.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_054013750.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_054003887.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054008205.1	5	Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920	"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability"
XP_054013889.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054003726.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_054013356.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-6798695;Reactome: R-HSA-9609523	"Sphingolipid de novo biosynthesis";"Neutrophil degranulation";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054005287.1	8	MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Cholesterol biosynthesis"
XP_054012027.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053995583.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054008801.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053998210.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_053995768.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_054009760.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053996330.1	9	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054007768.1	58	Reactome: R-HSA-5607764;Reactome: R-HSA-5689901;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601	"CLEC7A (Dectin-1) signaling";"Metalloprotease DUBs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_054001838.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053998349.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054014762.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_054013684.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054005381.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054001891.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054010742.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events"
XP_054014630.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation"
XP_054007861.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054001731.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054004720.1	7	MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363	"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_054008477.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053995861.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053996309.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_054010473.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080	"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I"
XP_054004326.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053998001.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054008412.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053995265.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054000190.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054001233.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054001046.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_054015480.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054002902.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_054002053.1	6	Reactome: R-HSA-8939211;Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565	"ESR-mediated signaling";"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054007165.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053999794.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_054012094.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_054000290.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053997842.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054013002.1	3	KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3	"Methane metabolism";"Serine biosynthesis";"Glycine, serine and threonine metabolism"
XP_054014884.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054008788.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_054008220.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321	"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_053998167.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054005301.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695	"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation"
XP_053999779.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054004549.1	4	MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_054006869.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054002982.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054016085.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054009772.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053997475.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054016616.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054000938.1	30	Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-5696400;Reactome: R-HSA-2564830;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-6781823	"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Dual Incision in GG-NER";"Cytosolic iron-sulfur cluster assembly";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex"
XP_054010567.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054005475.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054013543.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054015400.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054014048.1	11	Reactome: R-HSA-6782135;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-68962	"Dual incision in TC-NER";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Activation of the pre-replicative complex"
XP_054003683.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054015047.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054005049.1	5	MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00510+1.3.1.94;Reactome: R-HSA-4755579;Reactome: R-HSA-193048	"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis"
XP_054003807.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054013809.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_053999806.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_054008429.1	19	Reactome: R-HSA-163765;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5172;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;MetaCyc: PWY-5538	"ChREBP activates metabolic gene expression";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Acetyl-coa biosynthesis III (from citrate)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Pyruvate fermentation to acetate VI"
XP_054001851.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_054014770.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_054015548.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944	"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2"
XP_054005107.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_054000150.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054015109.1	13	KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384	"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_053997107.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054011234.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764	"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling"
XP_054005437.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054012054.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053997207.1	13	Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883	"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II"
XP_054001155.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_054016020.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_053995503.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054016365.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054009869.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054015159.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_054005157.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054003014.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053999975.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054001205.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054010175.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_053996399.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_054002363.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_054001435.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054016246.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_054011564.1	5	KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046;Reactome: R-HSA-389661	"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glyoxylate metabolism and glycine degradation"
XP_054016033.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_054012004.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054001493.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_054003612.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053999690.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054007553.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_054007943.1	12	KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Signaling by FGFR1 in disease";"Relaxin signaling pathway"
XP_054008378.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054008798.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054003677.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054010871.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054010651.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054011296.1	11	Reactome: R-HSA-72163;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2173796;Reactome: R-HSA-350054;Reactome: R-HSA-210744	"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_054016719.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007	"Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy"
XP_054006443.1	29	Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-77075	"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Dual Incision in GG-NER";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_054003984.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054014734.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054001477.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054005522.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_054002767.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053997522.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_054015560.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053996754.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_053999937.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_054001708.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054009664.1	7	Reactome: R-HSA-201681;Reactome: R-HSA-5368598;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258	"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"Degradation of DVL"
XP_054001516.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_054015123.1	14	MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053	"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_054010407.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054015450.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_054000409.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054009056.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054014827.1	10	Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription"
XP_054007114.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054000981.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053996806.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053998038.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054004258.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054008295.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054013725.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054003355.1	4	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_054013823.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054003635.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054005351.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054004909.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_053995214.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054013334.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008046.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053997631.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054010408.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054008956.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054008171.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_054006811.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054001707.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948	"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_053999938.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053997022.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion"
XP_054011709.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053997755.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053997853.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054002768.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054015325.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs"
XP_054000399.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_053997673.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054005755.1	19	Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-5627123;Reactome: R-HSA-389359;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-8950505;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467	"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"Rho GTPase cycle";"DCC mediated attractive signaling";"RHO GTPases activate PAKs";"CD28 dependent Vav1 pathway";"MAPK6/MAPK4 signaling";"EGFR downregulation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs"
XP_054001478.1	10	MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411	"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_054012182.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054000779.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054010238.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_054015734.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054003751.1	2	KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270	"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate"
XP_054008962.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054013462.1	10	Reactome: R-HSA-977225;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;Reactome: R-HSA-2453864	"Amyloid fiber formation";"Urate conversion to allantoin III";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Urate conversion to allantoin II";"Neutrophil degranulation";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Retinoid cycle disease events"
XP_054001986.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-72163	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"mRNA Splicing - Major Pathway"
XP_054008335.1	7	Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-983170	"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"IRE1alpha activates chaperones";"PERK regulates gene expression";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_054008773.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation"
XP_054006115.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053998969.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054010712.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053998037.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054004257.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054014828.1	5	Reactome: R-HSA-1660499;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-1445148	"Synthesis of PIPs at the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054003420.1	19	Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"RAF activation";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_054008546.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-77289	"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054006215.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054003153.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054010833.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054000625.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054007822.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054004426.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053998319.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054010373.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054006132.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053996139.1	6	Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403	"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)"
XP_054003514.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054000754.1	2	Reactome: R-HSA-194840;Reactome: R-HSA-8876198	"Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs"
XP_053999250.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053998240.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054012504.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054005158.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054010950.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054004631.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054011730.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054005909.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_053999423.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins"
XP_053997158.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054011876.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-4341670	"MHC class II antigen presentation";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Sialic acid metabolism";"Defective NEU1 causes sialidosis"
XP_054006718.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054003485.1	3	Reactome: R-HSA-349425;Reactome: R-HSA-8951664;MetaCyc: PWY-7511	"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Protein ubiquitination"
XP_054010540.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011336.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829	"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054012643.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
XP_054008797.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054003678.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054000806.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054008377.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_054014450.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"2-LTR circle formation"
XP_054015547.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-5628897	"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes"
XP_054014230.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054005549.1	11	Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973	"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation"
XP_054013184.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054006556.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054007542.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054008383.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054000856.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054015048.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_054012192.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054006562.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054007446.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053996459.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054011905.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054009811.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054001970.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054010820.1	4	MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902	"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)"
XP_054006452.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054016163.1	6	MetaCyc: PWY-7433;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_054005438.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054007665.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054011723.1	8	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_054006946.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054007003.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053997959.1	20	Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion synthesis by REV1";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_054011774.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997108.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054016520.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053998026.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054004301.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054005959.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_054014109.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054009506.1	8	MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00240+2.7.4.9;Reactome: R-HSA-499943;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_054004107.1	7	MetaCyc: PWY-7625;MetaCyc: PWY-6352;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11	"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PI";"Phosphatidylinositol signaling system"
XP_054007710.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_054009718.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054008063.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion"
XP_054016414.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041	"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle"
XP_054008787.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_054015796.1	17	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1221632;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6783310	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Relaxin signaling pathway";"Meiotic synapsis";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Fanconi Anemia Pathway"
XP_054004437.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053999981.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054003433.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9022692	"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Regulation of MECP2 expression and activity"
XP_054004049.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_054013406.1	5	Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-69205;Reactome: R-HSA-68949;Reactome: R-HSA-68962	"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription";"Orc1 removal from chromatin";"Activation of the pre-replicative complex"
XP_053999409.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events"
XP_053997923.1	17	MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7222;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7197	"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_053999139.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054000937.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054001329.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054010568.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054011327.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054013136.1	4	Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054015390.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054008826.1	10	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)"
XP_053998581.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231	"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053997803.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054013043.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054003701.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053999239.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_054007316.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054014289.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054004287.1	22	Reactome: R-HSA-70171;KEGG: 00500+5.3.1.9;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7347;MetaCyc: PWY-6992;MetaCyc: PWY-7238;Reactome: R-HSA-70263;MetaCyc: PWY-622;MetaCyc: PWY-6981;MetaCyc: PWY-5384;MetaCyc: PWY-3801;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5514;MetaCyc: PWY-621;MetaCyc: PWY-5054;MetaCyc: PWY-6142;Reactome: R-HSA-6798695;MetaCyc: PWY-5659;MetaCyc: PWY-8013;KEGG: 00520+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-7385	"Glycolysis";"Starch and sucrose metabolism";"Pentose phosphate pathway";"Sucrose biosynthesis III";"1,5-anhydrofructose degradation";"Sucrose biosynthesis II";"Gluconeogenesis";"Starch biosynthesis";"Chitin biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"Sucrose degradation II (sucrose synthase)";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose degradation III (sucrose invertase)";"D-sorbitol biosynthesis I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"TP53 Regulates Metabolic Genes";"1,3-propanediol biosynthesis (engineered)"
XP_054001442.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054003183.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054010626.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_054007144.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054009586.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466	"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis"
XP_053999821.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054000896.1	24	KEGG: 04150+2.7.11.11;Reactome: R-HSA-8963896;Reactome: R-HSA-9634600;Reactome: R-HSA-392517;Reactome: R-HSA-5621575;Reactome: R-HSA-9010642;Reactome: R-HSA-442720;Reactome: R-HSA-422356;Reactome: R-HSA-5610783;Reactome: R-HSA-8853659;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;Reactome: R-HSA-5687128;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-4420097;Reactome: R-HSA-111931;Reactome: R-HSA-5610785;Reactome: R-HSA-163358;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-5610780;Reactome: R-HSA-163615;Reactome: R-HSA-163560	"mTOR signaling pathway";"HDL assembly";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Rap1 signalling";"CD209 (DC-SIGN) signaling";"ROBO receptors bind AKAP5";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Regulation of insulin secretion";"Degradation of GLI2 by the proteasome";"RET signaling";"DARPP-32 events";"Hedgehog 'off' state";"MAPK6/MAPK4 signaling";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"VEGFA-VEGFR2 Pathway";"PKA-mediated phosphorylation of CREB";"GLI3 is processed to GLI3R by the proteasome";"PKA-mediated phosphorylation of key metabolic factors";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI1 by the proteasome";"PKA activation";"Triglyceride catabolism"
XP_053999225.1	57	Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176	"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_053997785.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054010805.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_054005785.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054012152.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053997999.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054001875.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053995363.1	13	Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1	"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes"
XP_054010925.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054008986.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054007363.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054001962.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054002553.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events"
XP_054006570.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054011634.1	22	Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-432142;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752	"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Platelet sensitization by LDL";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated"
XP_054011354.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054011800.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054001724.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_054001393.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054009482.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053996176.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054003888.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation"
XP_054013204.1	14	Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167200	"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_054015756.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054011015.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054014480.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_054009021.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054010010.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054015973.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053996290.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_054001837.1	12	Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-5250924;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-749476;Reactome: R-HSA-73762	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation"
XP_054010980.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054011839.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054015924.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_054016216.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858	"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity"
XP_053995767.1	8	Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873	"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation"
XP_053996190.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053997288.1	3	Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_054012028.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053999280.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053997720.1	4	KEGG: 00860+1.14.14.18;Reactome: R-HSA-917937;MetaCyc: PWY-5874;Reactome: R-HSA-189483	"Porphyrin and chlorophyll metabolism";"Iron uptake and transport";"Heme degradation I";"Heme degradation"
XP_053996225.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053997989.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054009264.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_054005989.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054005375.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005733.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054003791.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054015623.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_054009164.1	2	Reactome: R-HSA-196780;Reactome: R-HSA-3371599	"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_054010637.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054005795.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_054003831.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054005893.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054000639.1	5	KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation"
XP_054006482.1	13	Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-112043	"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"PLC beta mediated events"
XP_054008353.1	5	Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_054015706.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_054000886.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054007614.1	17	MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7205	"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation"
XP_053997231.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054012415.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_054009596.1	9	Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356	"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_054003405.1	5	KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine"
XP_054006586.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054004297.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054015017.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_054003135.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054010855.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012432.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_054003212.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054014476.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_053999290.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054005337.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054005657.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_054000600.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053997337.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054000374.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054004391.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054011304.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_054001787.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054011789.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054012202.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053999541.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_054011670.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054001063.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876	"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs"
XP_053999176.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054009413.1	10	Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"T cell receptor signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Regulation of TNFR1 signaling"
XP_054001826.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054012536.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054013628.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054003738.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054007819.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054013279.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053998322.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053999276.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054010251.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054001906.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054006021.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054008329.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053998498.1	3	MetaCyc: PWY-6558;Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_054005917.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_053996417.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054003165.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053997161.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054004368.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054005161.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054014647.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events"
XP_054010816.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054005588.1	14	MetaCyc: PWY-3781;MetaCyc: PWY-7254;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00190+1.3.5.1	"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Oxidative phosphorylation"
XP_053995385.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054006479.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-381676	"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_053998010.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053996141.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054003861.1	3	MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803	"Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II"
XP_054015089.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_054002858.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054013643.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053997865.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054002229.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism"
XP_054005763.1	16	Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-6811558;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-512988;Reactome: R-HSA-912526	"CD28 dependent PI3K/Akt signaling";"RET signaling";"Signaling by SCF-KIT";"Interleukin-7 signaling";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin receptor SHC signaling"
XP_053997972.1	57	Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin"
XP_053997087.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054006196.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_054003583.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_054004088.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6794361	"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins"
XP_054010501.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053998703.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054012456.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054007726.1	10	Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004	"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity"
XP_054001719.1	7	KEGG: 00860+6.1.1.17;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;MetaCyc: PWY-5188	"Porphyrin and chlorophyll metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_054012942.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_054004587.1	29	Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-167158	"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"Formation of the HIV-1 Early Elongation Complex"
XP_054011717.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053995544.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054001571.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054015648.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054007544.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054001146.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_054000864.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-6367	"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism"
XP_054011392.1	11	KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-6608;MetaCyc: PWY-7821;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5381	"Nicotinate and nicotinamide metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)"
XP_054005367.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054015369.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054002253.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053998431.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054012552.1	33	Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-69273;Reactome: R-HSA-69656;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-77075	"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_053998101.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054011963.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-69481;Reactome: R-HSA-532668;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-174184	"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"G2/M Checkpoints";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_054007887.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054001246.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;MetaCyc: PWY-7221	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis"
XP_054007065.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054012194.1	4	KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"HATs acetylate histones"
XP_053995320.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054001033.1	6	MetaCyc: PWY-7286;Reactome: R-HSA-8868766;MetaCyc: PWY-6829;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;MetaCyc: PWY-7285	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"rRNA processing in the mitochondrion";"Trna methylation (yeast)";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"Methylwyosine biosynthesis"
XP_053995887.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_054006564.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054015882.1	18	MetaCyc: PWY-5913;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6638;MetaCyc: PWY-7383	"Partial TCA cycle (obligate autotrophs)";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Tyrosine metabolism";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_054008810.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_053998201.1	22	MetaCyc: PWY-6433;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5353;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7053;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-7035	"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis"
XP_053998626.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764	"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Neddylation";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling"
XP_054001095.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_054005097.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_054004219.1	3	Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807	"Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism"
XP_054000025.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053999472.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053997097.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054014961.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054002203.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_054000360.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_054016255.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053998976.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054013113.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053998151.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054006134.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053999141.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054007824.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_054007775.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053995653.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_054016155.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_054013213.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053998251.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054007873.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_054004031.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054011056.1	5	Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-376172	"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"DSCAM interactions"
XP_054013579.1	6	MetaCyc: PWY-4981;MetaCyc: PWY-6922;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-3341	"L-proline biosynthesis II (from arginine)";"L-Ndelta-acetylornithine biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)"
XP_054012406.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054013711.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053999417.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_054004573.1	9	Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096	"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation"
XP_053999845.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054002701.1	8	KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_054003416.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837	"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases"
XP_054016851.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053998488.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054016671.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054015892.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6906	"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation"
XP_054007737.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054011869.1	5	MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347	"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis"
XP_054007629.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054005622.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054007897.1	12	KEGG: 00230+2.1.2.2;KEGG: 00230+6.3.3.1;MetaCyc: PWY-6613;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Purine metabolism";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Biotin transport and metabolism";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_054015732.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054012184.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053995897.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053997622.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_054004410.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054003740.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053997073.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053997024.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_054009454.1	2	Reactome: R-HSA-8934593;Reactome: R-HSA-69231	"Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1"
XP_054002808.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054013192.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054003346.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053998729.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4	"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism"
XP_054013464.1	10	MetaCyc: PWY-5691;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;Reactome: R-HSA-975634;Reactome: R-HSA-6798695;Reactome: R-HSA-977225;MetaCyc: PWY-7849	"Urate conversion to allantoin I";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Retinoid metabolism and transport";"Neutrophil degranulation";"Amyloid fiber formation";"Urate conversion to allantoin III"
XP_054010714.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053997531.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054008722.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054009045.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_054010075.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053996539.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054014618.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_054006532.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_054002888.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054012204.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054016233.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054009427.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054016046.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054011302.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_054001005.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_054011841.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053998291.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_054007693.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054016403.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054005558.1	17	Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-2559580;Reactome: R-HSA-111448;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1912408;Reactome: R-HSA-69205;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-2559585;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-9616222;Reactome: R-HSA-113501	"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Oxidative Stress Induced Senescence";"Activation of NOXA and translocation to mitochondria";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"Pre-NOTCH Transcription and Translation";"G1/S-Specific Transcription";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oncogene Induced Senescence";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional regulation of granulopoiesis";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_054016133.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054012104.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053995355.1	4	Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10	"Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053997468.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053998324.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054010591.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-7559	"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione degradation (DUG pathway"
XP_054014260.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_053998373.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053999940.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_054010319.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053998735.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054000317.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_054011096.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_054003529.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054006106.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054011145.1	11	Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-1251985	"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4"
XP_053996448.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054010538.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998712.1	4	Reactome: R-HSA-166058;Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-975138	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"
XP_054002183.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_054000211.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053995857.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_054006484.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-381676	"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_054015852.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008571.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_054008719.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054000111.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_054015023.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054015074.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054000039.1	26	Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-5621575	"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"CD209 (DC-SIGN) signaling"
XP_054010037.1	17	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1433557;Reactome: R-HSA-8953750;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-75035;Reactome: R-HSA-6796648	"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Signaling by SCF-KIT";"Transcriptional Regulation by E2F6";"Thermogenesis";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054008033.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_054014469.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054009156.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054008095.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053996318.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054013594.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_054004058.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053995612.1	13	MetaCyc: PWY-7384;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes"
XP_053998397.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054005619.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054003463.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054012486.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054013102.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_054012513.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054008365.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053996940.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_053998458.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_054008932.1	6	Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_054004008.1	9	Reactome: R-HSA-75955;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events"
XP_054013202.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_054011086.1	8	Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;KEGG: 00514+2.4.1.109	"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Other types of O-glycan biosynthesis"
XP_053998067.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053998783.1	4	KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041;Reactome: R-HSA-156581	"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II";"Methylation"
XP_053997960.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway"
XP_053999968.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054010168.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway"
XP_054005960.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_053999539.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_054007807.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053998281.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054016185.1	17	Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-8951664;Reactome: R-HSA-174048;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-8853884	"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Neddylation";"APC/C:Cdc20 mediated degradation of Cyclin B";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX"
XP_054012179.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054000782.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054015802.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_054015341.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054015764.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054015030.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_053996460.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054012628.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054015922.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053998181.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054008616.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054012496.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054007142.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054009515.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053997149.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054006156.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054005149.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054015147.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054008085.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054007471.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_054010026.1	18	MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism"
XP_054011521.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054015247.1	17	MetaCyc: PWY-6611;MetaCyc: PWY-4202;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6644;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-7179;MetaCyc: PWY-6608;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5695	"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Fluoroacetate and fluorothreonine biosynthesis";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Neutrophil degranulation";"Guanine and guanosine salvage";"Pyrimidine metabolism";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Inosine 5'-phosphate degradation"
XP_054002791.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_053997249.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053996169.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054002235.1	10	MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70263;KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00010+5.3.1.1	"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Gluconeogenesis";"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis"
XP_054013415.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_054016788.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054009484.1	18	MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Ether lipid metabolism"
XP_054007994.1	5	KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00020+4.1.1.32	"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)"
XP_054010863.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011352.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053997007.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054002293.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054010765.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053997716.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_054005508.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Glycolysis";"Fructose and mannose metabolism"
XP_053997508.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_054001055.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054002405.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054002193.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.36	"3-phosphoinositide degradation";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system"
XP_054011034.1	5	Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-917937	"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"Neddylation";"Iron uptake and transport"
XP_054016826.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_054009015.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054010361.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054001945.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054006696.1	5	MetaCyc: PWY-3781;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-6692;MetaCyc: PWY-7082	"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)"
XP_054010526.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054007701.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054014030.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053998388.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_054013682.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-156827	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054000460.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_053998601.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053998226.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053997507.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_054009839.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171	"Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions"
XP_054001646.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054003710.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053999792.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012092.1	12	Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167243	"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery"
XP_054016605.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_053997008.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053995495.1	56	Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168	"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054016787.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054006850.1	11	Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_054008414.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054006670.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054004007.1	15	Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-167246	"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"Tat-mediated elongation of the HIV-1 transcript"
XP_054008263.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_053998457.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656	"Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling"
XP_054013741.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054011586.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_054010081.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054015843.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_054016383.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_053999039.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054008761.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054012627.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_054010911.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_054009032.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054007928.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054014147.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6362;MetaCyc: PWY-6365;Reactome: R-HSA-1855204;MetaCyc: PWY-6366;KEGG: 00562+2.7.1.134+2.7.1.159	"Factors involved in megakaryocyte development and platelet production";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism"
XP_054006428.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_054010167.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398	"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway"
XP_053999967.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054012983.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-4086398	"Glucagon-type ligand receptors";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway"
XP_054009800.1	4	Reactome: R-HSA-446203;Reactome: R-HSA-879415;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"Asparagine N-linked glycosylation";"Advanced glycosylation endproduct receptor signaling";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_054003966.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_053999211.1	4	Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-77075	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_054012684.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054009995.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_054008071.1	6	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_053995485.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577	"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21"
XP_054004814.1	12	Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mTORC1-mediated signalling";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053999782.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054015523.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053995858.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054015574.1	24	Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877	"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase"
XP_054010537.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011413.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054008533.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_054013692.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054015618.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054006015.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053998398.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054007514.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054009696.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_054004558.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054004468.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_053997467.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053995253.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)"
XP_053998331.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054002954.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_053998040.1	3	Reactome: R-HSA-1369062;Reactome: R-HSA-8964058;Reactome: R-HSA-9029569	"ABC transporters in lipid homeostasis";"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054005557.1	17	Reactome: R-HSA-8953750;Reactome: R-HSA-69205;Reactome: R-HSA-1912408;Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-2559580;Reactome: R-HSA-111448;Reactome: R-HSA-1538133;Reactome: R-HSA-139915;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-113501;Reactome: R-HSA-9616222;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-2173796;Reactome: R-HSA-2559585	"Transcriptional Regulation by E2F6";"G1/S-Specific Transcription";"Pre-NOTCH Transcription and Translation";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Oxidative Stress Induced Senescence";"Activation of NOXA and translocation to mitochondria";"G0 and Early G1";"Activation of PUMA and translocation to mitochondria";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional regulation of granulopoiesis";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oncogene Induced Senescence"
XP_054015559.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054006920.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054014866.1	4	KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
XP_054002065.1	7	KEGG: 00230+3.6.1.15;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7185	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP dephosphorylation I"
XP_054009428.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054001505.1	9	Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex"
XP_054016773.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054012750.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054016655.1	2	KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984	"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_054002887.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054005058.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054007420.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054011164.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054016393.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_054016442.1	3	Reactome: R-HSA-6785807;Reactome: R-HSA-8878166;Reactome: R-HSA-8939902	"Interleukin-4 and Interleukin-13 signaling";"Transcriptional regulation by RUNX2";"Regulation of RUNX2 expression and activity"
XP_053996713.1	2	Reactome: R-HSA-1268020;MetaCyc: PWY-7533	"Mitochondrial protein import";"Gliotoxin biosynthesis"
XP_053996447.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054014852.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_054016171.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053997947.1	10	Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape"
XP_054002807.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054015172.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_054009662.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_054006759.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054016329.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054013666.1	16	Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5693616;Reactome: R-HSA-3214847;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"HATs acetylate histones";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange"
XP_054006327.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054012929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054009890.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054015272.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054009064.1	6	Reactome: R-HSA-5684045;Reactome: R-HSA-390247;Reactome: R-HSA-9603798;Reactome: R-HSA-2046106;Reactome: R-HSA-2046105;Reactome: R-HSA-1369062	"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Beta-oxidation of very long chain fatty acids";"Class I peroxisomal membrane protein import";"alpha-linolenic acid (ALA) metabolism";"Linoleic acid (LA) metabolism";"ABC transporters in lipid homeostasis"
XP_054009730.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054007738.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_054000580.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054003819.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005219.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054004097.1	12	MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism"
XP_054013872.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-381771	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_053995212.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053998358.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054013332.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054005340.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054005119.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;Reactome: R-HSA-196807	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_054003093.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053997031.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_054012002.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054013315.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_054011562.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054005597.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_054000525.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_053996080.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054015311.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053995293.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852	"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Macroautophagy"
XP_054003614.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054014118.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054011452.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-9020702	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling"
XP_054002994.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054011946.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_053997098.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053995193.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054007405.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054016695.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-9609690;Reactome: R-HSA-6804757	"SUMOylation of transcription cofactors";"HCMV Early Events";"Regulation of TP53 Degradation"
XP_054005098.1	5	Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)"
XP_054006606.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053998487.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054011466.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054003982.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_054012776.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054010051.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053999076.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053995371.1	5	KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-2206305	"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D"
XP_054014660.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054004073.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053996910.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054006121.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054002242.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053995791.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054005649.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053999766.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054012066.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011506.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054011718.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054006336.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5674400;Reactome: R-HSA-165181;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Constitutive Signaling by AKT1 E17K in Cancer";"Inhibition of TSC complex formation by PKB";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_054013769.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_054010001.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054001840.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054004087.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis"
XP_054008216.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_054001071.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054006545.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054004763.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054006955.1	4	Reactome: R-HSA-6782315;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-156581	"tRNA modification in the nucleus and cytosol";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Methylation"
XP_054009759.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054011402.1	4	MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855	"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)"
XP_054007888.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_054014919.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_054016303.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1"
XP_054012334.1	5	Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-936440	"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling"
XP_054011232.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054012654.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_054003913.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_054001533.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_054006730.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054005368.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054004367.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053996418.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_053997844.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054014882.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054011215.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053998497.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_054013004.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_053997088.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054012859.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053999080.1	3	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
XP_054012780.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_054009905.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054002857.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054006384.1	5	MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;Reactome: R-HSA-201681	"Protein ubiquitination";"Ub-specific processing proteases";"Degradation of AXIN";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT"
XP_054002984.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054016016.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054009774.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054015589.1	52	Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-6796648	"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054005982.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_054015079.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053997077.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054000034.1	26	Reactome: R-HSA-1368082;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-8941856;Reactome: R-HSA-918233	"RORA activates gene expression";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway"
XP_054002688.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054003410.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling"
XP_054014818.1	10	Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508	"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_054000760.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054007989.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054009499.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053999264.1	4	Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118	"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation"
XP_054010055.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054014944.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054001765.1	3	KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_054010722.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054002475.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053995835.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_054006125.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_054007375.1	4	Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-196108	"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Pregnenolone biosynthesis"
XP_054007795.1	7	MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_054007893.1	5	Reactome: R-HSA-499943;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis"
XP_054010964.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053999570.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053995893.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand"
XP_053996482.1	6	Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16	"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Th1 and Th2 cell differentiation"
XP_054004346.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_054005614.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054002842.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053998353.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054013599.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-4981	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)"
XP_054003597.1	11	Reactome: R-HSA-5693571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Nonhomologous End-Joining (NHEJ)";"Thermogenesis";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054015315.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053997012.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054000366.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054005012.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_053995401.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_054002301.1	7	Reactome: R-HSA-1483213;MetaCyc: PWY-7886;MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782	"Synthesis of PE";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PC";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis"
XP_054014464.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054007401.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012109.1	6	Reactome: R-HSA-3322077;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;MetaCyc: PWY-622;KEGG: 00500+2.4.1.18	"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Starch and sucrose metabolism"
XP_054014113.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054015652.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054013217.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_054002437.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_054002207.1	18	Reactome: R-HSA-6783984;Reactome: R-HSA-204174;Reactome: R-HSA-71064;KEGG: 00260+1.8.1.4;KEGG: 00380+1.8.1.4;KEGG: 00620+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00010+1.8.1.4;KEGG: 00280+1.8.1.4;MetaCyc: PWY-5084;Reactome: R-HSA-70895;Reactome: R-HSA-71403;MetaCyc: PWY-5046;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00640+1.8.1.4;KEGG: 00020+1.8.1.4	"Glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Lysine catabolism";"Glycine, serine and threonine metabolism";"Tryptophan metabolism";"Pyruvate metabolism";"Lysine degradation";"Glycolysis / Gluconeogenesis";"Valine, leucine and isoleucine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Branched-chain amino acid catabolism";"Citric acid cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Propanoate metabolism";"Citrate cycle (TCA cycle)"
XP_053997093.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054006728.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054005035.1	14	MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7411	"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_054000916.1	9	MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-6983;MetaCyc: PWY-7442	"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis"
XP_054006280.1	14	Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397	"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_054009541.1	2	KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054002049.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054014579.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054009951.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054004577.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054012047.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724	"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_054008322.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053997819.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-8862803;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017	"Ethylene biosynthesis III (microbes)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes"
XP_053995812.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054003573.1	16	Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-180585	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Neddylation";"Vif-mediated degradation of APOBEC3G"
XP_053998329.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_054004078.1	2	Reactome: R-HSA-1660499;Reactome: R-HSA-1632852	"Synthesis of PIPs at the plasma membrane";"Macroautophagy"
XP_054007812.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054013272.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053998757.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053998478.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus"
XP_054011447.1	57	Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761	"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_054004583.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053996596.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053997144.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054007883.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054009225.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_054007785.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_054012908.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_054001037.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054011039.1	52	Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-983168	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054016497.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_053996264.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053995607.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054005363.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053995999.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053997363.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1222556	"Photosynthesis";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Oxidative phosphorylation";"ATP biosynthesis";"ROS and RNS production in phagocytes"
XP_053998986.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_054001969.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054005992.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054001538.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_053996570.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_054003844.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053997992.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_054007326.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053996747.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054001240.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054000145.1	7	Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-389661	"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation"
XP_053998620.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_054008816.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054007561.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_054011317.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054007451.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053998934.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005913.1	6	MetaCyc: PWY-6527;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317	"Stachyose degradation";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_054004165.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054011372.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054013647.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053995188.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054015769.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054012223.1	27	Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-159230	"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA"
XP_053997083.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054005767.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-1433557;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604	"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"Signaling by SCF-KIT";"RET signaling";"PIP3 activates AKT signaling"
XP_054014643.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation"
XP_054006190.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_054000302.1	5	MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7	"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis"
XP_054009728.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054016473.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053995288.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis"
XP_054001714.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053995549.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054014584.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054008765.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation"
XP_054007549.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429	"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053996556.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054008863.1	9	Reactome: R-HSA-69231;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-69656;Reactome: R-HSA-1538133	"Cyclin D associated events in G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1"
XP_053999115.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054015036.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053997966.1	4	MetaCyc: PWY-5642;Reactome: R-HSA-70895;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27	"2,4-dinitrotoluene degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"Valine, leucine and isoleucine degradation"
XP_053999215.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053996645.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_054016457.1	14	Reactome: R-HSA-1632852;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5620924;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"Macroautophagy";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Intraflagellar transport";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053997446.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054011080.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053995208.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-6798695	"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Neutrophil degranulation"
XP_054004849.1	5	Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4;Reactome: R-HSA-8963693	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_053996452.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054006569.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054012199.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054009430.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054002878.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053995438.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054002338.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054013745.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_054002297.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053996946.1	13	MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662	"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism"
XP_053997003.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054010867.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053995959.1	8	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Activation of RAC1";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053997710.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054012018.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053998605.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054001461.1	10	MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15	"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_054012517.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054004503.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054009011.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Unwinding of DNA";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
XP_054007923.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054007974.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_054001941.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053995974.1	6	MetaCyc: PWY-6906;MetaCyc: PWY-7077;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210	"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_054006250.1	13	Reactome: R-HSA-4420097;Reactome: R-HSA-416572;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"VEGFA-VEGFR2 Pathway";"Sema4D induced cell migration and growth-cone collapse";"Thermogenesis";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054012988.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054006474.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-983695	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_053999232.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783	"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Syndecan interactions";"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type"
XP_054008581.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135	"Human immunodeficiency virus 1 infection";"Signaling by high-kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation"
XP_054007803.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress"
XP_054015682.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054007705.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054012490.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053995687.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054004644.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695	"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation"
XP_054006150.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054005316.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054009239.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054011702.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054005029.1	7	KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;MetaCyc: PWY-7158	"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"Phenylketonuria";"L-phenylalanine degradation V"
XP_054015027.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053996811.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion"
XP_054006430.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_054016175.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054007853.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053995755.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054012189.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053995853.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054014266.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_054000392.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054003947.1	10	MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-5609977	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Galactose catabolism";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_054011090.1	8	KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Mannose type O-glycan biosynthesis"
XP_053998335.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_054003557.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053998962.1	4	Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_053998773.1	4	MetaCyc: PWY-5041;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581	"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"Methylation"
XP_053998875.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_053998724.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053998393.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054011076.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054011418.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_054003467.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054004553.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_054014594.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053998546.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054016040.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054003058.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_054016407.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053996132.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-156711	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events"
XP_054007697.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054007258.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054006139.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054012998.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053998312.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_053995258.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054011669.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054004114.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_054015692.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054008240.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053996232.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054016398.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054015094.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)"
XP_054005053.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_054016778.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054009423.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054016237.1	9	Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation"
XP_054002381.1	11	Reactome: R-HSA-512988;Reactome: R-HSA-389948;Reactome: R-HSA-114604;Reactome: R-HSA-210990;Reactome: R-HSA-432142;Reactome: R-HSA-909733;Reactome: R-HSA-912694;Reactome: R-HSA-391160;Reactome: R-HSA-877312;Reactome: R-HSA-388841;Reactome: R-HSA-9008059	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PD-1 signaling";"GPVI-mediated activation cascade";"PECAM1 interactions";"Platelet sensitization by LDL";"Interferon alpha/beta signaling";"Regulation of IFNA signaling";"Signal regulatory protein family interactions";"Regulation of IFNG signaling";"Costimulation by the CD28 family";"Interleukin-37 signaling"
XP_054009991.1	6	Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993	"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors"
XP_054007481.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_054008075.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054003122.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-113507	"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation"
XP_054014028.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998837.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054006779.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054016238.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_054007157.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054002785.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054013866.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_054014613.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054012609.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_054003619.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054007257.1	4	Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_054016408.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054007698.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053995698.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054015252.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053998838.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054013852.1	8	Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-180024	"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events"
XP_054013672.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054014027.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053998378.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054008575.1	9	Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_054015166.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054009676.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054000115.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_054008846.1	4	Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656	"Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling"
XP_054015266.1	5	Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111464	"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_053996443.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053999062.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053997529.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054015527.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054012924.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053995522.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_054010533.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination"
XP_054006754.1	17	Reactome: R-HSA-167152;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167290;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery"
XP_054000402.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054016324.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054011141.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054016735.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054006625.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781	"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression"
XP_053995426.1	3	MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144	"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis"
XP_053998403.1	4	KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2	"Selenocompound metabolism";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_054013059.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054007426.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054004822.1	5	Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530	"RAF/MAP kinase cascade";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_053999056.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054010840.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054006806.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054011417.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_053998295.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054003468.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054004902.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053995351.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054014094.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_054000506.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053995631.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053998046.1	4	Reactome: R-HSA-975144;Reactome: R-HSA-9020702;MetaCyc: PWY-7511;Reactome: R-HSA-937039	"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling";"Protein ubiquitination";"IRAK1 recruits IKK complex"
XP_054003558.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_054007631.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054002451.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054012518.1	3	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2"
XP_054013009.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053998563.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_054010344.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_054006676.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Neutrophil degranulation";"Macroautophagy";"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_054005849.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054000466.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054002131.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054001051.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054002019.1	6	Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761	"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)"
XP_054002401.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_054003508.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054012017.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054009779.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054000946.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054009511.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-8866427	"Clathrin-mediated endocytosis";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation"
XP_054014036.1	4	MetaCyc: PWY-6829;MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861	"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)"
XP_053999963.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054010163.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_054012072.1	5	Reactome: R-HSA-983231;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"Factors involved in megakaryocyte development and platelet production";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_054004542.1	4	MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494	"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism";"Choline degradation IV"
XP_054008081.1	6	Reactome: R-HSA-975578;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143	"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis"
XP_054007475.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_054016387.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507	"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_054016820.1	2	Reactome: R-HSA-2142700;Reactome: R-HSA-2142691	"Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054000562.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053996382.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054014084.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053998285.1	3	KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II"
XP_054005644.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection"
XP_053998429.1	25	Reactome: R-HSA-8941326;Reactome: R-HSA-8939245;Reactome: R-HSA-9616222;Reactome: R-HSA-8941284;Reactome: R-HSA-8939247;Reactome: R-HSA-8941333;Reactome: R-HSA-8878166;Reactome: R-HSA-8939246;Reactome: R-HSA-8877330;Reactome: R-HSA-8941858;Reactome: R-HSA-8939242;Reactome: R-HSA-8931987;Reactome: R-HSA-8935964;Reactome: R-HSA-8939256;Reactome: R-HSA-9018519;Reactome: R-HSA-8941332;Reactome: R-HSA-8939902;Reactome: R-HSA-8951911;Reactome: R-HSA-8936459;Reactome: R-HSA-8949275;Reactome: R-HSA-8940973;Reactome: R-HSA-8934593;Reactome: R-HSA-8939243;Reactome: R-HSA-8951936;Reactome: R-HSA-8939236	"RUNX2 regulates bone development";"RUNX1 regulates transcription of genes involved in BCR signaling";"Transcriptional regulation of granulopoiesis";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in WNT signaling";"Estrogen-dependent gene expression";"RUNX2 regulates genes involved in cell migration";"Regulation of RUNX2 expression and activity";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX1 Expression and Activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_054002812.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054009926.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_053996062.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054004710.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054010868.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054007107.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_054002298.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_054008361.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853	"Neutrophil degranulation";"Signal transduction by L1";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes"
XP_054002337.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054012659.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054016783.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054008744.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054016067.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_054012879.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_054002877.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054006937.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054002198.1	3	KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_054016568.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054003440.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053998881.1	4	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_053998435.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054004363.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054013882.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_054016431.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054014004.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_053995287.1	8	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_054009639.1	10	Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-9022699	"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"MECP2 regulates neuronal receptors and channels"
XP_054008210.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_054005768.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-1660499;Reactome: R-HSA-8853659;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-1257604	"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Synthesis of PIPs at the plasma membrane";"RET signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin-7 signaling";"PIP3 activates AKT signaling"
XP_054006870.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053999760.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054012060.1	5	Reactome: R-HSA-5358346;Reactome: R-HSA-901032;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-381038	"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"XBP1(S) activates chaperone genes"
XP_053995187.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_054015182.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008349.1	5	Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_054016805.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053999034.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054012734.1	5	MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6	"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_054008110.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_053998516.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053995381.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_054004083.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054004767.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054002481.1	6	Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands"
XP_053996096.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054003972.1	20	MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7726;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-6920	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)"
XP_054013089.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053999086.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054012786.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_054003865.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)"
XP_054011448.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184	"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_054000747.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053997861.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_054005861.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053998477.1	33	Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531	"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus"
XP_053999916.1	16	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569	"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054006784.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_054008419.1	12	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;KEGG: 04714+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Thermogenesis"
XP_054005265.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054003161.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054015504.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054016498.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054009794.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513	"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"RAF activation";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling"
XP_053997165.1	15	Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination"
XP_054012907.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-5689880;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_054004913.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RORA activates gene expression"
XP_054005346.1	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_054006727.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054016729.1	11	KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-6549;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-5675	"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Nitrate reduction V (assimilatory)"
XP_054002208.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_054008640.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053996632.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054012884.1	12	Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840	"G alpha (q) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"DCC mediated attractive signaling";"Rho GTPase cycle"
XP_054002438.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052	"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_054007658.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208	"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling"
XP_054009870.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053997593.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054004012.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054007878.1	5	Reactome: R-HSA-499943;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7176;MetaCyc: PWY-7177	"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II"
XP_054009650.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053995297.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_054002108.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054015464.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054007297.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053997535.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054002549.1	4	Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053998758.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054009896.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_054013892.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-141444	"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054015944.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053996366.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053998483.1	5	Reactome: R-HSA-3232118;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_054006886.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053999748.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054002923.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054010465.1	34	Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9639288;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5663220	"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amino acids regulate mTORC1";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"RHO GTPases Activate Formins"
XP_053997577.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053995224.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054007273.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_054002974.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053999302.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054006600.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054002803.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054006834.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054012390.1	9	Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_054004819.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054010646.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054007173.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053997078.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054016855.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054012770.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_054000021.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054014872.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054015113.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_054014652.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054014332.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;MetaCyc: PWY-5381	"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)"
XP_054001526.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_054003097.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054011940.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053995391.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054014054.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Intraflagellar transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054004093.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053997512.1	5	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_053998255.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053995519.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054007519.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054008424.1	13	MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;MetaCyc: PWY-7227;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_053996876.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053996336.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-432040	"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054013762.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054004385.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054002814.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_053998116.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054005642.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054013630.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054006348.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_054014082.1	7	MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Homoglutathione biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_054005044.1	8	Reactome: R-HSA-6791055;Reactome: R-HSA-71336;Reactome: R-HSA-163754;Reactome: R-HSA-8950505;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2	"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway"
XP_054014912.1	16	Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342;Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1236394	"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"Signaling by ERBB4"
XP_054011409.1	10	MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-5844;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-7996;MetaCyc: PWY-5891;MetaCyc: PWY-5839	"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis"
XP_054010708.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053999759.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054012059.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_054002057.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053997888.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054010516.1	19	Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-3000497;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-202733	"LDL remodeling";"Chylomicron assembly";"LDL clearance";"Scavenging by Class H Receptors";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"VLDL assembly";"Chylomicron remodeling";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall"
XP_054013756.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005565.1	7	KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_054001398.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054010477.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054015434.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054003451.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"mTORC1-mediated signalling";"Translation initiation complex formation";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054002468.1	7	Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517	"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid"
XP_054016816.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053997455.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_054001237.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053997781.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053999606.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_054003607.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054014362.1	8	Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Signaling by Hippo";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054014935.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054001871.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054004065.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054007844.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054009910.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053995844.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656	"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry"
XP_054010342.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_054014356.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054011200.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053996384.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054005283.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054012023.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053999774.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054007587.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054010155.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054000404.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-2151201;Reactome: R-HSA-3214847	"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis";"HATs acetylate histones"
XP_054006752.1	17	Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167152;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-75955;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV elongation complex in the absence of HIV Tat";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation"
XP_054001388.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054007746.1	3	MetaCyc: PWY-6689;MetaCyc: PWY-7803;Reactome: R-HSA-6784531	"Trna splicing I";"Trna splicing II";"tRNA processing in the nucleus"
XP_053996327.1	27	KEGG: 04926+2.7.11.1;Reactome: R-HSA-5358747;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5674400;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5467348;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-5250924;Reactome: R-HSA-5467340;Reactome: R-HSA-75815;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-5358752;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358751;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-4641262	"Relaxin signaling pathway";"S33 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by AKT1 E17K in Cancer";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"Truncations of AMER1 destabilize the destruction complex";"Human cytomegalovirus infection";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"B-WICH complex positively regulates rRNA expression";"AXIN missense mutants destabilize the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"mTOR signaling pathway";"APC truncation mutants have impaired AXIN binding";"T41 mutants of beta-catenin aren't phosphorylated";"Human immunodeficiency virus 1 infection";"S45 mutants of beta-catenin aren't phosphorylated";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_054015179.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_054011250.1	10	MetaCyc: PWY-6361;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6369;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism"
XP_054005898.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_054010255.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_053999064.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054006025.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054005738.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054011150.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053995524.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_054011423.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053997738.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053998945.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_053997277.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_054006766.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054004904.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_054013659.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_053998555.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054010671.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_054008638.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053998465.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082	"Estrogen-dependent gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression"
XP_054008358.1	5	KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage"
XP_054007119.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054004395.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054001601.1	57	Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858	"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity"
XP_054004824.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054009348.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_054016551.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054002440.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054004333.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054004653.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-881907	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_053997112.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054004775.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054001457.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053997235.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253	"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_053996905.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_054005293.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054013706.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_054003231.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054015254.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054008691.1	15	Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-174048	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B"
XP_054015592.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053997293.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_054011938.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053997135.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_054003019.1	24	Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878	"Recycling pathway of L1";"Gap junction assembly";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport"
XP_054003401.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054002508.1	3	Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691	"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling"
XP_054009864.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054003131.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_054005193.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053997405.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_053996221.1	5	MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_054016714.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054008487.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054013987.1	5	MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661	"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation"
XP_054007410.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;Reactome: R-HSA-1483166	"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA"
XP_054002310.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054012147.1	4	Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_054004897.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_054002149.1	3	Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B	"Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates"
XP_054009418.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054009076.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054005371.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054003893.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053997371.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054003795.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054003375.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_054002249.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054003835.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_054005791.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_054007122.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054014066.1	5	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_053996799.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054006832.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053998840.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054003481.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism"
XP_054010195.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_053996379.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054010403.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053995222.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_054000532.1	6	Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange"
XP_054010046.1	17	Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05165+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-1433557;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-6796648;Reactome: R-HSA-75035	"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human papillomavirus infection";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Signaling by SCF-KIT";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Transcriptional Regulation by E2F6";"Thermogenesis";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"TP53 Regulates Transcription of DNA Repair Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_054002972.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054001473.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_053997229.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053999789.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054002865.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054005229.1	57	Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424	"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling"
XP_054013380.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_054011951.1	28	Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-912446;Reactome: R-HSA-6782210;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-110320;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;Reactome: R-HSA-5358606	"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"HSF1 activation";"Translesion Synthesis by POLH";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_054000621.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054005514.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054003829.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053997514.1	12	MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053	"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II"
XP_054008778.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054003697.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053998595.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_053999696.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054001742.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054014334.1	5	KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264	"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging"
XP_054014654.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054008407.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_054003158.1	14	MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-500657;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043	"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events"
XP_054004693.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054006317.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054016319.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053996686.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054004355.1	11	Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001	"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade"
XP_054014725.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1"
XP_054008137.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054008331.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054007467.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_054015294.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_054015552.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-203927	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis"
XP_054016037.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054010798.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054006039.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053995557.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054010378.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054001497.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_054007557.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_054010838.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054000484.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054007058.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054015194.1	9	Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching"
XP_054005153.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054014386.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054006967.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053996800.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054009641.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-8936459	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054004677.1	6	KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22	"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism"
XP_054003022.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054001510.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_054008175.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054015456.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_054004984.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053995947.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_054013060.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054003974.1	20	MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-6920;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7337;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7288	"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"6-gingerol analog biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_054016581.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053996696.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053998585.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054015043.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054003687.1	16	Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243	"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery"
XP_053997701.1	7	Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-165054;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749	"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Rev-mediated nuclear export of HIV RNA";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs"
XP_054009317.1	7	Reactome: R-HSA-9022692;MetaCyc: PWY-6074;KEGG: 00100+1.3.1.70;MetaCyc: PWY-2541;MetaCyc: PWY-7154;Reactome: R-HSA-191273;MetaCyc: PWY-8026	"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Steroid biosynthesis";"Phytosterol biosynthesis (plants)";"Ergosterol biosynthesis II";"Cholesterol biosynthesis";"Sterol biosynthesis (methylotrophs)"
XP_054013770.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_054013390.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_054008388.1	10	KEGG: 00640+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-6536;KEGG: 00250+2.6.1.19;MetaCyc: PWY-4321;Reactome: R-HSA-916853	"Propanoate metabolism";"4-aminobutanoate degradation I";"Butanoate metabolism";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Alanine, aspartate and glutamate metabolism";"L-glutamate degradation IV";"Degradation of GABA"
XP_053999799.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_053997203.1	13	MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52	"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series"
XP_054013836.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054009792.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)"
XP_054009000.1	15	Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation"
XP_054008126.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053999985.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_054000427.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053997103.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054011728.1	7	KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053996670.1	4	Reactome: R-HSA-9610379;Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-72203	"HCMV Late Events";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"Processing of Capped Intron-Containing Pre-mRNA"
XP_054005433.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054003491.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054003208.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054014002.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_054008068.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1"
XP_054013884.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_054016026.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_054012118.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054014953.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_054014370.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"PKA activation"
XP_054003108.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_054007661.1	7	Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-166208	"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTORC1-mediated signalling"
XP_054003438.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation"
XP_054012218.1	18	MetaCyc: PWY-7184;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7205	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"CMP phosphorylation"
XP_054012892.1	12	Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"G alpha (q) signalling events";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"DCC mediated attractive signaling";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054000494.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012732.1	5	MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6	"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_054013547.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053999920.1	16	Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897	"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway";"TP53 Regulates Metabolic Genes"
XP_054014776.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_054016863.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054004471.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_054011125.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054010220.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054015284.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054010788.1	7	MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8	"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism"
XP_054012961.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054003437.1	19	Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719	"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors"
XP_054016526.1	6	KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Synthesis of PA"
XP_053998932.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054008458.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590	"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling"
XP_054003107.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_053998365.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054010906.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053999106.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_054007440.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054012117.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054008067.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054001976.1	5	MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism"
XP_054001151.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_054013209.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785	"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome"
XP_054008783.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054000789.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054010787.1	7	KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-7586;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-882	"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)"
XP_054000304.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053997807.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054009539.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_054008281.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054003049.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054005683.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_054011600.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_054000995.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054011834.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_054014236.1	9	Reactome: R-HSA-70263;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901	"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation"
XP_054006550.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_054013548.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054011374.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054011794.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054001855.1	9	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695	"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"mTORC1-mediated signalling";"Macroautophagy";"Neutrophil degranulation"
XP_054000933.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998616.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054005142.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054008387.1	10	Reactome: R-HSA-916853;MetaCyc: PWY-4321;KEGG: 00250+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6537	"Degradation of GABA";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation V";"beta-Alanine metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism";"Butanoate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II"
XP_054016081.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053997142.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053996156.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_054014184.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053997471.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054005242.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053995249.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins"
XP_054014284.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054003475.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054013130.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053996256.1	13	Reactome: R-HSA-202433;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-1855204;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2029485;Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-6351	"Generation of second messenger molecules";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"Synthesis of IP3 and IP4 in the cytosol";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Role of phospholipids in phagocytosis";"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_054004808.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_054016167.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_054011639.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054011727.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011359.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054001729.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053999484.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053997994.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054003842.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054000428.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054005994.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054015370.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054007508.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053996262.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054002098.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054016537.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054015052.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054006539.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_054000985.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054008540.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054015903.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054003426.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837	"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases"
XP_054007057.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054015654.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054007558.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429	"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_054003351.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054010837.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054009550.1	11	Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-5689880;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-3214847	"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"HATs acetylate histones"
XP_054000379.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841	"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"PKMTs methylate histone lysines"
XP_053997693.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_054010377.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054009460.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054005355.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053995468.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5663220	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"RHO GTPases Activate Formins"
XP_054015725.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_054016038.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054007468.1	3	Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161	"Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation"
XP_054003522.1	3	Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725	"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation"
XP_054001010.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_053995948.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_054008373.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_054009940.1	42	Reactome: R-HSA-5334118;Reactome: R-HSA-73772;Reactome: R-HSA-9610379;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-427359;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-3214841;Reactome: R-HSA-5578749;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-427413;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-3214858;Reactome: R-HSA-2559586;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-3214815;Reactome: R-HSA-1912408;Reactome: R-HSA-2559582;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-1221632;Reactome: R-HSA-73728;Reactome: R-HSA-427389;Reactome: R-HSA-9616222;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565	"DNA methylation";"RNA Polymerase I Promoter Escape";"HCMV Late Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"PKMTs methylate histone lysines";"Transcriptional regulation by small RNAs";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"NoRC negatively regulates rRNA expression";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RMTs methylate histone arginines";"DNA Damage/Telomere Stress Induced Senescence";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDACs deacetylate histones";"Pre-NOTCH Transcription and Translation";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"Meiotic synapsis";"RNA Polymerase I Promoter Opening";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional regulation of granulopoiesis";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054007948.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053995814.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053996106.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054008833.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_054004485.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054013450.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_054000015.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_054004678.1	6	Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820	"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)"
XP_054014566.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054008712.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054016846.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054015228.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054010724.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054015859.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_053996484.1	6	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_054010962.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053998719.1	10	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"Ub-specific processing proteases";"HATs acetylate histones";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054014456.1	13	Reactome: R-HSA-419037;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-186797;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244	"NCAM1 interactions";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Signaling by PDGF";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Laminin interactions";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Collagen degradation";"Extracellular matrix organization"
XP_053999162.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054010655.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054011870.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_054000920.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-5664;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-6983;MetaCyc: PWY-7442;MetaCyc: PWY-6703	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Preq0 biosynthesis"
XP_054005984.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_054001805.1	6	MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;Reactome: R-HSA-196780	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism"
XP_054011041.1	52	Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-1236978	"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_054001703.1	12	Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700	"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus"
XP_054008138.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054004253.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053998033.1	10	KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153	"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"3-phosphoinositide biosynthesis";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection"
XP_053996515.1	18	Reactome: R-HSA-912446;Reactome: R-HSA-5685938;MetaCyc: PWY-7511;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-1221632;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579	"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Protein ubiquitination";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic synapsis";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange"
XP_053997014.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054001201.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_053999156.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054010171.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_054001626.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053998095.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054010956.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex"
XP_053999971.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054006318.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_054008408.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054002918.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054008238.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054002844.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054008777.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation"
XP_054005612.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054003698.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054004153.1	5	Reactome: R-HSA-9609523;Reactome: R-HSA-5694530;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Cargo concentration in the ER";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_054001101.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_054005904.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054007097.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_054006580.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054006611.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054001885.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_054014513.1	9	Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation"
XP_054001783.1	4	Reactome: R-HSA-111465;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5689880	"Apoptotic cleavage of cellular proteins";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Ub-specific processing proteases"
XP_053999479.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_054013476.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054001067.1	14	MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_054012509.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053996134.1	3	Reactome: R-HSA-9609523;Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_054003519.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054005395.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_054000759.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053997824.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054015694.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053997775.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053997873.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053998314.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054009590.1	7	MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466	"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis"
XP_053996404.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_053995598.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_054001458.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054003273.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054008675.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs"
XP_054008855.1	6	Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-434316	"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion"
XP_054009743.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_054009417.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054012148.1	4	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_054008488.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054013988.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)"
XP_053997278.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-73856	"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination"
XP_053997737.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)"
XP_054001900.1	7	Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052	"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion"
XP_054005278.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054005737.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054010695.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_053999270.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054011975.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054000394.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054010633.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633	"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_054015899.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_053996328.1	27	Reactome: R-HSA-8939902;Reactome: R-HSA-4641262;Reactome: R-HSA-5610785;Reactome: R-HSA-5358751;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5358752;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-3371453;KEGG: 04714+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-198323;Reactome: R-HSA-5467340;Reactome: R-HSA-5250924;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-5674400;Reactome: R-HSA-399956;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5467348;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5358747;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5610783;KEGG: 04926+2.7.11.1	"Regulation of RUNX2 expression and activity";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"GLI3 is processed to GLI3R by the proteasome";"S45 mutants of beta-catenin aren't phosphorylated";"Human immunodeficiency virus 1 infection";"T41 mutants of beta-catenin aren't phosphorylated";"mTOR signaling pathway";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"Regulation of HSF1-mediated heat shock response";"Thermogenesis";"Ubiquitin-dependent degradation of Cyclin D";"AKT phosphorylates targets in the cytosol";"AXIN missense mutants destabilize the destruction complex";"B-WICH complex positively regulates rRNA expression";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Constitutive Signaling by AKT1 E17K in Cancer";"CRMPs in Sema3A signaling";"PI3K-Akt signaling pathway";"Truncations of AMER1 destabilize the destruction complex";"Human cytomegalovirus infection";"S33 mutants of beta-catenin aren't phosphorylated";"Human papillomavirus infection";"Degradation of GLI2 by the proteasome";"Relaxin signaling pathway"
XP_054011389.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_053999564.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054007073.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054001387.1	17	KEGG: 00640+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;Reactome: R-HSA-200425	"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Pyruvate metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Carnitine metabolism"
XP_054004293.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation"
XP_054011676.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054000121.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054014592.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054008357.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL"
XP_054008637.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054016051.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053998964.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053999296.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054014470.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053996186.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054004405.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053998722.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;KEGG: 05165+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Ub-specific processing proteases";"HATs acetylate histones";"Human papillomavirus infection";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054012843.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053999045.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_054013998.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053998663.1	5	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053995261.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_054007261.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054004565.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054006845.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054014434.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054008307.1	4	Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903	"Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy"
XP_054003608.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054007161.1	27	Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159230	"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA"
XP_054004455.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_054000336.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054011926.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin"
XP_054000656.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8939902;Reactome: R-HSA-8948751	"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Regulation of RUNX2 expression and activity";"Regulation of PTEN stability and activity"
XP_054003381.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054001950.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053999234.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054006472.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054006241.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_054005385.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054004642.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_054001324.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054001793.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_054011754.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531	"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus"
XP_054001895.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054006141.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054005979.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054015977.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition"
XP_054007763.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054004044.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054001735.1	10	MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-8053;MetaCyc: PWY-5667	"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I"
XP_053995972.1	14	KEGG: 00966+2.6.1.42;Reactome: R-HSA-70895;MetaCyc: PWY-5076;MetaCyc: PWY-5104;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5078;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5057;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5108	"Glucosinolate biosynthesis";"Branched-chain amino acid catabolism";"L-leucine degradation III";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis III";"L-isoleucine degradation II";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis II";"L-valine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis V"
XP_054006590.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053995865.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054015636.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053997726.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999286.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054010986.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1"
XP_054008925.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054013189.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053996045.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054003187.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148	"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053997954.1	20	Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756	"Translesion Synthesis by POLH";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation"
XP_054011779.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054001238.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054005954.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_054002467.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053996270.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054001397.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054015935.1	3	Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096	"MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation"
XP_054011399.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_054016668.1	3	Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-450385	"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053996170.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-68884	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis"
XP_054015889.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054000709.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_054002058.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054005320.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053996564.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053997065.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054000384.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054008626.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-375165;Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-445095	"Neutrophil degranulation";"NCAM signaling for neurite out-growth";"Nephrin family interactions";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins"
XP_053998180.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054015031.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis"
XP_054013093.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_054005961.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_054014097.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054003965.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_054011414.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_054008534.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_054003872.1	4	Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695	"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation"
XP_054005272.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054012927.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054015573.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Cilium Assembly";"Gap junction assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_054009303.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-8964011;Reactome: R-HSA-3359463	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective CUBN causes hereditary megaloblastic anemia 1"
XP_054002929.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation"
XP_054010611.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054015524.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054013819.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054004715.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins"
XP_054011585.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_054004813.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_054002809.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054006757.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054012683.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053998225.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054012242.1	24	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5607764;Reactome: R-HSA-5218921;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-354192;KEGG: 04714+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837	"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"CLEC7A (Dectin-1) signaling";"VEGFR2 mediated cell proliferation";"Downstream TCR signaling";"GPVI-mediated activation cascade";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"Human papillomavirus infection";"Relaxin signaling pathway";"Integrin signaling";"Thermogenesis";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation"
XP_054001645.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_053995496.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D"
XP_054012142.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054013077.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054001466.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_054009016.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054011163.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054004218.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_054006695.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054002790.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054016774.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054011263.1	19	Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-428543;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-114604;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-389359;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097	"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Rho GTPase cycle";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"Inactivation of CDC42 and RAC1";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade";"MAPK6/MAPK4 signaling";"EGFR downregulation";"CD28 dependent Vav1 pathway";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway"
XP_053998821.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379	"ECM proteoglycans";"Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres"
XP_054008586.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054007254.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_053998951.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276	"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_054008413.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054002874.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053998176.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054001232.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054002334.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054010472.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054014161.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"snRNP Assembly";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053998276.1	12	KEGG: 00640+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00720+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-7118	"Propanoate metabolism";"L-isoleucine biosynthesis V";"Carbon fixation pathways in prokaryotes";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Lupulone and humulone biosynthesis";"Pyruvate metabolism";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Chitin degradation to ethanol"
XP_054014917.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_054009757.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054001402.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054002903.1	4	Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5362768	"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_054010141.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053999551.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054011840.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_054014763.1	3	MetaCyc: PWY-7158;MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96	"L-phenylalanine degradation V";"Tetrahydropteridine recycling";"Folate biosynthesis"
XP_054014865.1	4	KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188	"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_054004089.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-1660499	"Macroautophagy";"Synthesis of PIPs at the plasma membrane"
XP_053998190.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053997647.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054013767.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_054001718.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_054010845.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_053995582.1	4	Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_054006016.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054006478.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775	"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Ion homeostasis"
XP_054012984.1	24	Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-9009391	"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling"
XP_054015587.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054008596.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005589.1	12	MetaCyc: PWY-6842;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-7901;MetaCyc: PWY-6309;MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-1187;MetaCyc: PWY-2821;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13	"Glutathione-mediated detoxification II";"Tryptophan catabolism";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Glucosinolate biosynthesis from tyrosine";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism"
XP_054012857.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054002228.1	5	Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_054016384.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)"
XP_054012612.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_054013992.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-203927	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis"
XP_054000110.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053998499.1	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_054009996.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054007486.1	52	Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-5250924;Reactome: R-HSA-203927;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-167243;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-167200	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"B-WICH complex positively regulates rRNA expression";"MicroRNA (miRNA) biogenesis";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_054000210.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054004369.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054008164.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_054001115.1	7	Reactome: R-HSA-70263;KEGG: 00710+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11	"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Pentose phosphate pathway"
XP_054008570.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_054006063.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_054016670.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054001534.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I"
XP_054003914.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_054012775.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053999075.1	3	MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_053998991.1	20	Reactome: R-HSA-6782210;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-69091;Reactome: R-HSA-110312	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Polymerase switching";"Translesion synthesis by REV1"
XP_054011465.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054016789.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_054016304.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054016850.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054005509.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054009837.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_053997509.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_053996268.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054004764.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999140.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054000526.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_054013316.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_054005148.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054003682.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053999591.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054004030.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054009312.1	7	MetaCyc: PWY-2541;MetaCyc: PWY-7154;MetaCyc: PWY-8026;Reactome: R-HSA-191273;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;KEGG: 00100+1.3.1.70	"Phytosterol biosynthesis (plants)";"Ergosterol biosynthesis II";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Steroid biosynthesis"
XP_054000361.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_053999240.1	11	Reactome: R-HSA-202733;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928	"Cell surface interactions at the vascular wall";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Syndecan interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis"
XP_054006826.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054000744.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053997248.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053998150.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054016696.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-9609690;Reactome: R-HSA-6804757	"SUMOylation of transcription cofactors";"HCMV Early Events";"Regulation of TP53 Degradation"
XP_054011945.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_054009875.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054009773.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054009724.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_054007284.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054002983.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053997530.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053999538.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_054010169.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430	"Ca2+ pathway";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling"
XP_053999969.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054013542.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054012629.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054006383.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Ub-specific processing proteases"
XP_053999037.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053995184.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054012897.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054009546.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054004147.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_054007184.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy"
XP_054008645.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053998459.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_054013003.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_054014716.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054009956.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053998938.1	11	KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;Reactome: R-HSA-901042;MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-6908;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-196819	"Thiamine metabolism";"Thiamine salvage IV (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Vitamin B1 (thiamin) metabolism"
XP_053997745.1	57	Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481	"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints"
XP_054008452.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054013952.1	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_054004009.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053996319.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054003860.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_054003094.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054013053.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054014468.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_054016015.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054005618.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054009826.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_053997618.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054013822.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054014057.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053998239.1	11	MetaCyc: PWY-5913;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-7254;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42	"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism"
XP_054004059.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054005523.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_054002977.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054008718.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053997523.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins"
XP_054005160.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053996075.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_054010539.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997160.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054005574.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_054015122.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154	"Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase"
XP_053998981.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054000038.1	26	Reactome: R-HSA-9018519;Reactome: R-HSA-2122947;Reactome: R-HSA-3371568;Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-210744;Reactome: R-HSA-400253;Reactome: R-HSA-3214847;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-8866907;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-1368082;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-5621575;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973	"Estrogen-dependent gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"Attenuation phase";"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Circadian Clock";"HATs acetylate histones";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"CD209 (DC-SIGN) signaling";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"
XP_054016799.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_054014814.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_054006377.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-6793080	"Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion"
XP_054004023.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053995321.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054003528.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_054006171.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_054010318.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_054006956.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly"
XP_054007942.1	12	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5655302;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Signaling by FGFR1 in disease";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"Human immunodeficiency virus 1 infection"
XP_053998200.1	22	MetaCyc: PWY-6958;MetaCyc: PWY-7619;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7053;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-5353;MetaCyc: PWY-7601;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7036;MetaCyc: PWY-7724	"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)"
XP_053995942.1	4	KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204;Reactome: R-HSA-964975	"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate"
XP_054004074.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_054006271.1	8	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5173105	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"O-linked glycosylation"
XP_053998430.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_054006442.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)"
XP_053995566.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_054001596.1	5	Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;KEGG: 00670+1.5.1.20	"Metabolism of folate and pterines";"Folate transformations II (plants)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate"
XP_054002636.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053999026.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053998100.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054006962.1	6	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_054012887.1	12	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"mTOR signaling pathway";"G alpha (q) signalling events";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"G alpha (12/13) signalling events"
XP_054011505.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054012065.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_053999765.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_054006724.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054016634.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_054001570.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054008115.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_054014619.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_054000846.1	4	KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_054005469.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053995552.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054001492.1	14	Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-6798695	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"Neutrophil degranulation"
XP_054003613.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053997469.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054007552.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-264642	"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_053995294.1	8	Reactome: R-HSA-3371571;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724	"HSF1-dependent transactivation";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription"
XP_054002362.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054006546.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054001264.1	10	Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-9620244	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"NrCAM interactions";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"Long-term potentiation"
XP_054015557.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054008215.1	5	Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796	"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation"
XP_054010500.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_054004523.1	2	Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7	"Purine salvage";"Purine metabolism"
XP_054014222.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_054006731.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_054016206.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054000591.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054007066.1	4	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_054001245.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"RAF/MAP kinase cascade"
XP_054001096.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_054010317.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_054012642.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation"
XP_053999526.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053995874.1	6	Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6	"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Peroxisomal protein import";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism"
XP_054015558.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_054002434.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3	"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism"
XP_054007874.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_054001841.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054007725.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054009285.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054012455.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054007823.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism"
XP_054010372.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054006133.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054013114.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054007052.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054005059.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054010000.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054016532.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_054014058.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054003594.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054001748.1	3	KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661;MetaCyc: PWY-5129	"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)"
XP_054013463.1	10	MetaCyc: PWY-7849;Reactome: R-HSA-977225;Reactome: R-HSA-975634;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;Reactome: R-HSA-3000171;MetaCyc: PWY-5691	"Urate conversion to allantoin III";"Amyloid fiber formation";"Retinoid metabolism and transport";"Urate conversion to allantoin II";"Neutrophil degranulation";"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Retinoid cycle disease events";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin I"
XP_054005617.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054008772.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation"
XP_053998399.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_053995386.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054015619.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053999081.1	3	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_054012781.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_054014467.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054003152.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012	"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053997866.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053999267.1	4	Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118	"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation"
XP_054002582.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053997023.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_054000037.1	26	Reactome: R-HSA-933541;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-9617629;Reactome: R-HSA-8866907;Reactome: R-HSA-1368082;Reactome: R-HSA-2644606	"TRAF6 mediated IRF7 activation";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of FOXO transcriptional activity by acetylation";"Activation of the TFAP2 (AP-2) family of transcription factors";"RORA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053997074.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054003166.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system"
XP_054010211.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054012183.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053999167.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054007780.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054005672.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054013943.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054008717.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_054007929.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053997341.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054013644.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054004148.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_054005341.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054012898.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053997764.1	9	Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Neutrophil degranulation";"mTORC1-mediated signalling";"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_054006285.1	4	KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis"
XP_053999038.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054003345.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054005030.1	7	KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1	"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine degradation V";"Phenylketonuria";"Phenylalanine metabolism";"Phenylalanine metabolism"
XP_054015960.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054013042.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_054009046.1	2	Reactome: R-HSA-202433;Reactome: R-HSA-376176	"Generation of second messenger molecules";"Signaling by ROBO receptors"
XP_054010782.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054008062.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_054009891.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053998937.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-212436;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-9018519	"RORA activates gene expression";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Estrogen-dependent gene expression"
XP_054001615.1	3	Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271	"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism"
XP_054004509.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_054011314.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163	"Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism"
XP_054003432.1	19	Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9022692	"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Regulation of MECP2 expression and activity"
XP_054002513.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054012135.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053995604.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054009838.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_053996267.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054006120.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054009378.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054001760.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053995370.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720;Reactome: R-HSA-6798695	"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation"
XP_054002154.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054006563.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054012193.1	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_054001034.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053998856.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053995790.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012405.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054006788.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054003415.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932	"Trafficking of AMPA receptors";"RAF activation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB"
XP_054016162.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation"
XP_054012293.1	17	MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37	"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms"
XP_054002254.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054011722.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053997009.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054007543.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053995543.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011444.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054000026.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054012371.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_054016256.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135	"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation"
XP_054004530.1	26	Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9648025	"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Recycling pathway of L1";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Kinesins";"EML4 and NUDC in mitotic spindle formation"
XP_054015249.1	17	Reactome: R-HSA-74217;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-7179;MetaCyc: PWY-6627;MetaCyc: PWY-7179-1;MetaCyc: PWY-6644;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-4202	"Purine salvage";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Guanine and guanosine salvage";"Neutrophil degranulation";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation I";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation II";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage III";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)"
XP_053998862.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053996081.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth"
XP_054002496.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053998704.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054001366.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_054008382.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054005147.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054003584.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_054015310.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054010669.1	9	MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241	"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_054007082.1	5	KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00630+4.2.1.3	"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes";"Iron uptake and transport";"Glyoxylate and dicarboxylate metabolism"
XP_054012678.1	3	MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141	"Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054002227.1	5	MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-6344	"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)"
XP_054015763.1	11	MetaCyc: PWY-8052;Reactome: R-HSA-2029485;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8051	"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I"
XP_053997089.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054008096.1	6	Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;MetaCyc: PWY-7511	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Protein ubiquitination"
XP_054015087.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054015972.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054012858.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053995684.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054004647.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_054012485.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054002127.1	13	MetaCyc: PWY-5122;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7102;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-7721;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-7141	"Geranyl diphosphate biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"(3S)-linalool biosynthesis"
XP_054016479.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_054006477.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-381676	"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Effects of PIP2 hydrolysis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_054001313.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054008841.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054005919.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054008070.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072	"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex"
XP_054016564.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_053995750.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_053998896.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054009758.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054014918.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054006105.1	5	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-390471	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054011095.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_053998736.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054002552.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054016270.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054009483.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054010864.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054006205.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054007362.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054007935.1	5	Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6289;MetaCyc: PWY-6012;MetaCyc: PWY-6012-1	"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis";"Petrobactin biosynthesis";"Acyl carrier protein metabolism";"Acyl carrier protein activation"
XP_054007421.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054010076.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054016296.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_054003182.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_054016045.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054006801.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_054013768.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_054001717.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-110312	"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Translesion synthesis by REV1"
XP_054011719.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054002566.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053998330.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053996110.1	4	KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis"
XP_053995356.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-8866427	"Clathrin-mediated endocytosis";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation"
XP_053998041.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054004441.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_054013078.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054013416.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_054014524.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_054006671.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054010766.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_054001056.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598	"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis"
XP_054005715.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054000461.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_053997813.1	10	MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-2201;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757	"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations I";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"One carbon pool by folate";"Metabolism of folate and pterines"
XP_053997715.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_053998323.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_054002406.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054007700.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054012495.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054016134.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053995700.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054012103.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054008615.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_054007694.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054012433.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_054016404.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054006155.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053997099.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054012203.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054004961.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_054005099.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_054008086.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054004217.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_054003464.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053998359.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_054011915.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054014098.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_054008352.1	5	MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695	"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation"
XP_054003554.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_054015531.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_054008760.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events"
XP_053999110.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054004311.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_054010910.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054013346.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-75953	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation"
XP_054005118.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054003192.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054011616.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054006758.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054013740.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054015073.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054005660.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_054009105.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_054008366.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_053995627.1	7	MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176	"Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis"
XP_054001869.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054006483.1	13	Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-422356	"Effects of PIP2 hydrolysis";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion"
XP_054005892.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054007627.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053995899.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_054002184.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_053998886.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054012928.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054015622.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_054011962.1	7	Reactome: R-HSA-71064;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;Reactome: R-HSA-71403;MetaCyc: PWY-5084	"Lysine catabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_053997997.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053999487.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_054014061.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_054006505.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054011773.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011393.1	11	MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-5381;MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-7185;KEGG: 00760+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6608	"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Pyridine nucleotide cycling (plants)";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation III"
XP_053996308.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_054012553.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_054016164.1	6	Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;MetaCyc: PWY-7433	"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_054000805.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_054007602.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053995602.1	13	KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384	"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_054005609.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_054010650.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054010870.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997609.1	16	MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-2221;MetaCyc: PWY-1622;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-8004;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-5723;Reactome: R-HSA-70263	"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Formaldehyde assimilation I (serine pathway)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Rubisco shunt";"Gluconeogenesis"
XP_054014187.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054000201.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production"
XP_054004425.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053999691.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054003582.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_054008384.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054014287.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054003978.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054013183.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_054013044.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_054015288.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053997804.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054002028.1	4	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_054009465.1	18	MetaCyc: PWY-6803;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1483166	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA"
XP_053999638.1	3	Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686	"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I"
XP_054006116.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054005350.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053998348.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_054012529.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054002527.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910	"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs"
XP_054013642.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054005762.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-1257604	"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"RET signaling";"Signaling by SCF-KIT";"PIP3 activates AKT signaling"
XP_054011797.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054006216.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054009646.1	3	Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887	"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation"
XP_054000980.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054011837.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_054008955.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054014608.1	18	Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783	"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Plasmalogen degradation"
XP_054015451.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_054003434.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-438066	"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion transport by P-type ATPases";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_054005756.1	19	Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-428543;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-5627123;Reactome: R-HSA-2029482;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-114604;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-5687128	"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"Inactivation of CDC42 and RAC1";"Rho GTPase cycle";"DCC mediated attractive signaling";"RHO GTPases activate PAKs";"Regulation of actin dynamics for phagocytic cup formation";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade";"CD28 dependent Vav1 pathway";"EGFR downregulation";"MAPK6/MAPK4 signaling"
XP_054015326.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_054013888.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_054008064.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_054016747.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226	"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054009945.1	42	Reactome: R-HSA-3214858;Reactome: R-HSA-5617472;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-9616222;Reactome: R-HSA-171306;Reactome: R-HSA-5250924;Reactome: R-HSA-4551638;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-427413	"RMTs methylate histone arginines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"HDACs deacetylate histones";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Transcriptional regulation of granulopoiesis";"Packaging Of Telomere Ends";"B-WICH complex positively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"DNA methylation";"HCMV Late Events";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"HATs acetylate histones";"Meiotic recombination";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"NoRC negatively regulates rRNA expression"
XP_054015131.1	4	Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Spermidine biosynthesis III";"Arginine and proline metabolism"
XP_054014658.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054014338.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054003470.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054015019.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053997518.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_054008825.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_054007315.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054002415.1	3	KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis"
XP_054014197.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054008774.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054008606.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054015835.1	4	Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204	"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)"
XP_053996487.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054000357.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_054010639.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054005300.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054000637.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054000729.1	42	Reactome: R-HSA-201722;Reactome: R-HSA-212300;Reactome: R-HSA-3214847;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-110331;Reactome: R-HSA-110329;Reactome: R-HSA-427413;Reactome: R-HSA-5578749;Reactome: R-HSA-912446;Reactome: R-HSA-110330;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-5334118;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-5693571;Reactome: R-HSA-8936459;Reactome: R-HSA-1221632;Reactome: R-HSA-73728;Reactome: R-HSA-427389;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-5693565;Reactome: R-HSA-9616222;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-2559586;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-606279;Reactome: R-HSA-3214815;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-3214858;Reactome: R-HSA-110328;Reactome: R-HSA-1912408;Reactome: R-HSA-2559582	"Formation of the beta-catenin:TCF transactivating complex";"PRC2 methylates histones and DNA";"HATs acetylate histones";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"Cleavage of the damaged purine";"Cleavage of the damaged pyrimidine";"NoRC negatively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Meiotic recombination";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"DNA methylation";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Meiotic synapsis";"RNA Polymerase I Promoter Opening";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional regulation of granulopoiesis";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"DNA Damage/Telomere Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDACs deacetylate histones";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"RMTs methylate histone arginines";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Pre-NOTCH Transcription and Translation";"Senescence-Associated Secretory Phenotype (SASP)"
XP_053999308.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053997854.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054005987.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_054005072.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053997072.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053997987.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054004490.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_053995817.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-383280	"Regulation of gene expression in beta cells";"Nuclear Receptor transcription pathway"
XP_054003279.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054007445.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054002345.1	11	Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1	"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection"
XP_054007817.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054008327.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_054008759.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054012644.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_054016021.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_054007666.1	5	Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-350054;Reactome: R-HSA-1912408	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation"
XP_054004572.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053998360.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054007054.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_054006555.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053999424.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-9609690;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236	"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"HCMV Early Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054015198.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012503.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011063.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054016534.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_054014771.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054006465.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_054001789.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053996358.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053999473.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_054004517.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497	"Estrogen-dependent gene expression";"ESR-mediated signaling";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054011787.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054001304.1	15	Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897	"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway";"TP53 Regulates Metabolic Genes"
XP_054009116.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054007872.1	18	MetaCyc: PWY-6803;Reactome: R-HSA-1482801;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7783;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7416;Reactome: R-HSA-1483166	"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PS";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Synthesis of PA"
XP_054000855.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054001933.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_054007332.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053997339.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054010374.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054005339.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053997879.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_054010834.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054009344.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_053996331.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895	"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis"
XP_054009761.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053998039.1	27	Reactome: R-HSA-674695;Reactome: R-HSA-111367;Reactome: R-HSA-975956;Reactome: R-HSA-8851708;Reactome: R-HSA-167200;Reactome: R-HSA-6807505;Reactome: R-HSA-191859;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-167158;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-112382;Reactome: R-HSA-159236	"RNA Polymerase II Pre-transcription Events";"SLBP independent Processing of Histone Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Signaling by FGFR2 IIIa TM";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes";"snRNP Assembly";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of the HIV-1 Early Elongation Complex";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Minor Pathway";"mRNA Capping";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of RNA Pol II elongation complex";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053998111.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_054008032.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054003462.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-6796648	"Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053998967.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054008800.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054008354.1	5	MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695	"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation"
XP_054003294.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054015853.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053997060.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054015755.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053999068.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053997894.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053997325.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054010511.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054015624.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_054005734.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053998713.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_054013751.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054000408.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207	"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases"
XP_054012583.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054005786.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054008799.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053997786.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054000291.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053998000.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054010926.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054015481.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054000191.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054001064.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_054006533.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_054011303.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_054001890.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_053996237.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054006595.1	6	KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;Reactome: R-HSA-1855183	"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol"
XP_054009868.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053995860.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_054001730.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054015909.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_054004721.1	7	KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702	"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I"
XP_054014631.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation"
XP_054005907.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968;Reactome: R-HSA-5358606;Reactome: R-HSA-6796648	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes"
XP_054007860.1	3	KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217	"Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage"
XP_054015158.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_054011620.1	16	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054000735.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054015697.1	4	MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-7119	"Ceramide degradation (generic)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_054001662.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_053998317.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054010625.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054000324.1	11	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway";"p38MAPK events";"PI3K-Akt signaling pathway";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection"
XP_054016402.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_054005827.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054010862.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011353.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054001394.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054011633.1	22	Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5358751;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5675221	"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"S45 mutants of beta-catenin aren't phosphorylated";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"Separation of Sister Chromatids";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway"
XP_054002292.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053996068.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054010975.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053999175.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054005957.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053997957.1	20	Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210	"Translesion synthesis by REV1";"Polymerase switching";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054012535.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054016562.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054002192.1	6	KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368	"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation"
XP_053996567.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_054015208.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054013808.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_054014475.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054010856.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053999040.1	3	Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_054004400.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054007143.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054003184.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054008428.1	19	Reactome: R-HSA-6798695;MetaCyc: PWY-5538;MetaCyc: PWY-7384;Reactome: R-HSA-75105;KEGG: 00020+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-5537;Reactome: R-HSA-163765;MetaCyc: PWY-5392;MetaCyc: PWY-6728;MetaCyc: PWY-5172	"Neutrophil degranulation";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Reductive TCA cycle II";"Methylaspartate cycle";"Acetyl-coa biosynthesis III (from citrate)"
XP_054005547.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-69231	"T cell receptor signaling pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1"
XP_053998641.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_054009533.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053997390.1	9	Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351	"G alpha (q) signalling events";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_054010069.1	5	Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787	"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state"
XP_054000885.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054015705.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751	"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity"
XP_054005770.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_054009595.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054006868.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054012416.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_054004548.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_053999778.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053997770.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054006585.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259	"Purine metabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism"
XP_054004047.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054003406.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_054015974.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053999137.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054012512.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053996226.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism"
XP_054013103.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053996126.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054005836.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_054014107.1	26	Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-8866654;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-4615885;Reactome: R-HSA-1362277;Reactome: R-HSA-69091;Reactome: R-HSA-6804114;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-69205;Reactome: R-HSA-174414;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-174417;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606	"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"E3 ubiquitin ligases ubiquitinate target proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA replication proteins";"Transcription of E2F targets under negative control by DREAM complex";"Polymerase switching";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"G1/S-Specific Transcription";"Processive synthesis on the C-strand of the telomere";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_054005376.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005796.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_054013203.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_054003502.1	6	MetaCyc: PWY-6309;MetaCyc: PWY-7765;MetaCyc: PWY-7717;Reactome: R-HSA-71240;KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651	"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde"
XP_053997796.1	5	MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-7391	"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)"
XP_054009033.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053999138.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054013242.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157	"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions"
XP_054005400.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_054016382.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)"
XP_053999408.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69205	"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G1/S-Specific Transcription"
XP_053997230.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054015688.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054003776.1	4	Reactome: R-HSA-71737;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Pyrophosphate hydrolysis";"Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_053999777.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054005230.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_054004547.1	2	KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788	"Starch and sucrose metabolism";"Cellulose degradation II (fungi)"
XP_054006867.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054011483.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054008256.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_054013142.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053998169.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054003790.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054003830.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054015301.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-7385	"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Glycolysis";"Methane metabolism";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)"
XP_054003604.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_054001186.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054009719.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-5689880	"HATs acetylate histones";"Ub-specific processing proteases"
XP_054013994.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Ca2+ pathway"
XP_054012614.1	6	Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.66	"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system"
XP_054001286.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_053995847.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_054007415.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054015207.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053997209.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053996568.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053999793.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054006020.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053999735.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054011155.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053997109.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054001234.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053997958.1	20	Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-69091	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Polymerase switching"
XP_054016062.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054004796.1	1	Reactome: R-HSA-114608	"Platelet degranulation"
XP_053996067.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053996885.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054010474.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation"
XP_054002817.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054004390.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054011671.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054005548.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-428890;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8939236	"Regulation of actin dynamics for phagocytic cup formation";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Role of ABL in ROBO-SLIT signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs"
XP_053999540.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_054013927.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_054008427.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054016056.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053999291.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053997047.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054002666.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054015049.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054013683.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053998460.1	3	Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828	"TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis"
XP_053996712.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane"
XP_054012144.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054004325.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_054014853.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_054011801.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054001045.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054006571.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054016443.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_054006719.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053995266.1	5	Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-3371571	"mTOR signalling";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"HSF1-dependent transactivation"
XP_053998500.1	3	KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_054012244.1	24	Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-165158;Reactome: R-HSA-9634635;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-114604;Reactome: R-HSA-5218921	"RSK activation";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"G beta:gamma signalling through PI3Kgamma";"Activation of AKT2";"Estrogen-stimulated signaling through PRKCZ";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Thermogenesis";"FCERI mediated NF-kB activation";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation"
XP_054003859.1	13	MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-7384	"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_054000651.1	2	MetaCyc: PWY-5905;Reactome: R-HSA-204626	"Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine"
XP_054003679.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054013677.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_054007166.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053999820.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054005828.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053998318.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway"
XP_054006095.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054013612.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054001454.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054001270.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054015157.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_054005159.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053997908.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_054016392.1	4	Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6	"Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_053997159.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054016772.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054011205.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054013014.1	5	Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-75896;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import"
XP_054013355.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054003725.1	3	Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565	"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_054008532.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_054011412.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577	"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21"
XP_053997721.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_053999281.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_054013693.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054014909.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_054005721.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053996291.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054003052.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054010981.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054014829.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-1445148;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499	"Neutrophil degranulation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane"
XP_053999939.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053996324.1	9	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053996793.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053996373.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054000407.1	8	Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111464	"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_054009020.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054000778.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054005274.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054002769.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053999067.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054015522.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053999783.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054003066.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_054014733.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054003983.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_054004854.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4720475;KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_054016521.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-6787639;Reactome: R-HSA-727802	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis";"Transport of nucleotide sugars"
XP_054003899.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952	"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions"
XP_054008328.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_054004072.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054016366.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054007818.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054003739.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_054013629.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054001971.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053995818.1	2	Reactome: R-HSA-210745;Reactome: R-HSA-383280	"Regulation of gene expression in beta cells";"Nuclear Receptor transcription pathway"
XP_053995292.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724	"Macroautophagy";"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription"
XP_054007554.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle"
XP_054011120.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_054012952.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_054016034.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_054011563.1	10	MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571	"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis"
XP_054012003.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054015297.1	14	MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4	"Stigma estolide biosynthesis";"Ether lipid metabolism";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Synthesis of PE";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Synthesis of PC";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism"
XP_054005299.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER"
XP_054002364.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054011788.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053996637.1	13	KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52	"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism"
XP_054004518.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_054011220.1	3	Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import"
XP_054014231.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054016632.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_053997199.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054015391.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054013333.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053995213.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054015771.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054013824.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054003700.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053996976.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054005476.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054003092.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054012710.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054008134.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053997476.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054004659.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_054013904.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054014657.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053997988.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054005988.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_054015124.1	14	KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055	"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis"
XP_053999980.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054009663.1	7	Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-4641262	"PCP/CE pathway";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"Degradation of DVL";"RHO GTPases Activate Formins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_053996753.1	6	KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-6731	"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation V";"Starch degradation III"
XP_054007579.1	24	Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-4086398;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-392851	"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor"
XP_054007711.1	3	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053995579.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054000358.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_054015273.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054009055.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-190861	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"Recycling pathway of L1";"Gap junction assembly"
XP_054005189.1	4	Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-1268020;Reactome: R-HSA-3371453	"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Mitochondrial protein import";"Regulation of HSF1-mediated heat shock response"
XP_054011838.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_054015187.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097	"Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway"
XP_054013544.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053996805.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054003421.1	19	Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000	"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"RAF activation"
XP_053998347.1	3	Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-525793	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Myogenesis"
XP_053997289.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_054012029.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054005289.1	8	MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;Reactome: R-HSA-191273	"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis"
XP_054003636.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054015287.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054013726.1	12	MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9	"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism"
XP_054008296.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_054008045.1	7	MetaCyc: PWY-7807;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;MetaCyc: PWY-6610;Reactome: R-HSA-74217;MetaCyc: PWY-6605;Reactome: R-HSA-6798695	"Glyphosate degradation III";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Adenine salvage";"Purine salvage";"Adenine and adenosine salvage II";"Neutrophil degranulation"
XP_054001484.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15	"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_054003889.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054000681.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054013887.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054003750.1	4	MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;Reactome: R-HSA-5661270	"Glycerol degradation I";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Formation of xylulose-5-phosphate"
XP_054016748.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_054014883.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054001515.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_054008454.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054014607.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation"
XP_054011195.1	2	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_054014451.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054002094.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054010541.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054016302.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053997998.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054011233.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054003912.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_054001532.1	6	MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656	"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_053998241.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053998472.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054013979.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054014288.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054003977.1	20	MetaCyc: PWY-7007;MetaCyc: PWY-7858;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6	"Methyl ketone biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism"
XP_054014720.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054010176.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_054001206.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-174113	"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1"
XP_054011731.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054004804.1	5	Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-2219530	"PI3K Cascade";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_054010951.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999976.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054016245.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054001436.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053999251.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054009314.1	10	Reactome: R-HSA-444257;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"RSK activation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_053998590.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_054014188.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053998916.1	4	Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054002148.1	42	MetaCyc: PWY-6944;MetaCyc: PWY-7778;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;KEGG: 00903+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7726;MetaCyc: PWY-5109;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-7401;MetaCyc: PWY-6583;MetaCyc: PWY-6945;MetaCyc: PWY-7656;KEGG: 00640+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7779;MetaCyc: PWY-6863;MetaCyc: PWY-6435;MetaCyc: PWY-7606;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7007	"Androstenedione degradation";"2-methylpropene degradation";"Carbon fixation pathways in prokaryotes";"Benzoate degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Limonene and pinene degradation";"Fatty acid elongation";"Glutaryl-coa degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid degradation";"Geraniol degradation";"Benzoyl-coa degradation I (aerobic)";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Butanoate metabolism";"beta-Alanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol I";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Spodoptera littoralis pheromone biosynthesis";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Fatty acid degradation";"Fatty acid salvage";"Valine, leucine and isoleucine degradation";"Pyruvate fermentation to butanol II (engineered)";"Caprolactam degradation";"Butanoate metabolism";"Toluene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Methyl tert-butyl ether degradation";"Pyruvate fermentation to hexanol (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Aminobenzoate degradation";"Methyl ketone biosynthesis (engineered)"
XP_054009419.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_054003490.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054004279.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_054014277.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_054003988.1	9	Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7411	"Synthesis of PA";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)"
XP_054008834.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_053995813.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054003572.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-983168	"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054002248.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053995715.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_054013273.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054008374.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_054007813.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053997700.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-1655829;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-203927	"Transcriptional regulation by small RNAs";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis"
XP_054003517.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054015395.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053998615.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_054013519.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_054011939.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054000757.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053997694.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_054015653.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053996155.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_054016611.1	3	Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"TP53 Regulates Metabolic Genes";"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054015904.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054002509.1	16	Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339	"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane"
XP_054003018.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Gap junction assembly";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_054012507.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997092.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053999477.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation"
XP_054004470.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_054014135.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054008359.1	10	Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-6814122;Reactome: R-HSA-8948751;Reactome: R-HSA-201688;Reactome: R-HSA-8939243;Reactome: R-HSA-6798695;Reactome: R-HSA-445144	"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Neutrophil degranulation";"Signal transduction by L1"
XP_054003299.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_054008639.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054013658.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_053998352.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_053995218.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054002843.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_054010221.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053998760.1	14	MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-975634;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417	"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Retinoid metabolism and transport";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)"
XP_054014235.1	9	MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12;MetaCyc: PWY-5484;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis"
XP_054000996.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054009349.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_054004592.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053997013.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054007118.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053999921.1	16	Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway";"Estrogen-dependent gene expression"
XP_054004254.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054014293.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053998034.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054014831.1	2	Reactome: R-HSA-975634;Reactome: R-HSA-192456	"Retinoid metabolism and transport";"Digestion of dietary lipid"
XP_054001704.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665	"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells"
XP_054007660.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes"
XP_054015178.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_054009668.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053999105.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_054005983.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_053997983.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_054016525.1	6	MetaCyc: PWY-6952;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261	"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I"
XP_054015629.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054005739.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054011900.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054015278.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053995892.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054005899.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_054010723.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053997899.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054001975.1	5	KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22	"Glycerolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism"
XP_053996516.1	18	Reactome: R-HSA-5685942;Reactome: R-HSA-5689901;Reactome: R-HSA-8953750;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;MetaCyc: PWY-7511;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693616;Reactome: R-HSA-1221632	"HDR through Homologous Recombination (HRR)";"Metalloprotease DUBs";"Transcriptional Regulation by E2F6";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Protein ubiquitination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic synapsis"
XP_053997082.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054001754.1	23	Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-416482;Reactome: R-HSA-392851;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-420092	"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"Ca2+ pathway";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (12/13) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Glucagon-type ligand receptors"
XP_054011324.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054011373.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054007089.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_054011833.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_054010955.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054011735.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054014044.1	1	Reactome: R-HSA-419771	"Opsins"
XP_054016241.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054016472.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_054000620.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_054013381.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_054014642.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-170660	"PKA activation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway"
XP_053999255.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054000303.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054015385.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_054008784.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport"
XP_054008309.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_054016845.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054010656.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054014455.1	27	Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180746	"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein"
XP_053996412.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054004104.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_054003480.1	18	MetaCyc: PWY-1622;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00630+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-5913	"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Partial TCA cycle (obligate autotrophs)"
XP_054005912.1	6	MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;Reactome: R-HSA-70370;Reactome: R-HSA-5609978	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Defective GALT can cause Galactosemia"
XP_054001806.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism"
XP_054015320.1	5	MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817	"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_054015887.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054012058.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex"
XP_053997889.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_054007882.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_054008736.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_054013061.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054012467.1	12	Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_054003931.1	26	Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148	"MHC class II antigen presentation";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054002469.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression"
XP_054005993.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054001680.1	182	Reactome: R-HSA-937039;Reactome: R-HSA-5675221;Reactome: R-HSA-6791226;Reactome: R-HSA-174154;Reactome: R-HSA-72706;Reactome: R-HSA-937072;Reactome: R-HSA-69541;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-3769402;Reactome: R-HSA-168638;Reactome: R-HSA-72764;Reactome: R-HSA-180534;Reactome: R-HSA-8948747;Reactome: R-HSA-5687128;Reactome: R-HSA-2979096;Reactome: R-HSA-6783310;Reactome: R-HSA-1234176;Reactome: R-HSA-69231;Reactome: R-HSA-8852276;Reactome: R-HSA-8866654;Reactome: R-HSA-8866652;Reactome: R-HSA-1169408;Reactome: R-HSA-975144;Reactome: R-HSA-8875360;Reactome: R-HSA-1799339;Reactome: R-HSA-917937;Reactome: R-HSA-174048;Reactome: R-HSA-5684264;Reactome: R-HSA-9615710;Reactome: R-HSA-8854050;Reactome: R-HSA-4641263;Reactome: R-HSA-9633012;Reactome: R-HSA-2559582;Reactome: R-HSA-69601;Reactome: R-HSA-2559585;Reactome: R-HSA-195253;Reactome: R-HSA-1295596;Reactome: R-HSA-9646399;Reactome: R-HSA-1236974;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-3134975;Reactome: R-HSA-901032;Reactome: R-HSA-912631;Reactome: R-HSA-182971;Reactome: R-HSA-6804757;Reactome: R-HSA-5675482;Reactome: R-HSA-8876493;Reactome: R-HSA-5357956;Reactome: R-HSA-2408557;Reactome: R-HSA-937041;Reactome: R-HSA-187577;Reactome: R-HSA-209543;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-8863795;Reactome: R-HSA-5696400;Reactome: R-HSA-5654732;Reactome: R-HSA-8849469;Reactome: R-HSA-5205685;Reactome: R-HSA-205043;Reactome: R-HSA-5668541;Reactome: R-HSA-3322077;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-6781823;Reactome: R-HSA-69481;Reactome: R-HSA-110314;Reactome: R-HSA-1358803;Reactome: R-HSA-5656121;Reactome: R-HSA-5357905;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-6782135;Reactome: R-HSA-174178;Reactome: R-HSA-975956;Reactome: R-HSA-5658442;Reactome: R-HSA-5610785;Reactome: R-HSA-192823;Reactome: R-HSA-2173788;Reactome: R-HSA-8856828;Reactome: R-HSA-2672351;Reactome: R-HSA-5362768;Reactome: R-HSA-2122948;Reactome: R-HSA-6782210;Reactome: R-HSA-2894862;Reactome: R-HSA-382556;Reactome: R-HSA-936440;Reactome: R-HSA-209560;Reactome: R-HSA-5689896;Reactome: R-HSA-917729;Reactome: R-HSA-1236382;Reactome: R-HSA-2644606;Reactome: R-HSA-4641257;Reactome: R-HSA-445989;Reactome: R-HSA-5689901;Reactome: R-HSA-168927;Reactome: R-HSA-168928;Reactome: R-HSA-5607761;Reactome: R-HSA-110312;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;Reactome: R-HSA-532668;Reactome: R-HSA-2173791;Reactome: R-HSA-983168;Reactome: R-HSA-72689;Reactome: R-HSA-201681;Reactome: R-HSA-936964;Reactome: R-HSA-5655862;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-9637628;Reactome: R-HSA-72695;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-156827;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5689877;Reactome: R-HSA-2565942;Reactome: R-HSA-8941858;Reactome: R-HSA-977225;Reactome: R-HSA-5693607;Reactome: R-HSA-5654733;Reactome: R-HSA-68827;Reactome: R-HSA-975163;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-9013507;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-8856825;Reactome: R-HSA-400253;Reactome: R-HSA-2122947;Reactome: R-HSA-6807004;Reactome: R-HSA-9013973;Reactome: R-HSA-175474;Reactome: R-HSA-2173795;Reactome: R-HSA-1253288;Reactome: R-HSA-5654726;Reactome: R-HSA-9033241;Reactome: R-HSA-9014325;Reactome: R-HSA-6804760;Reactome: R-HSA-75815;Reactome: R-HSA-9613829;Reactome: R-HSA-5685942;Reactome: R-HSA-5610783;Reactome: R-HSA-2173796;Reactome: R-HSA-9020702;Reactome: R-HSA-975110;Reactome: R-HSA-9645460;Reactome: R-HSA-5689603;Reactome: R-HSA-5654727;Reactome: R-HSA-8951664;Reactome: R-HSA-174490;Reactome: R-HSA-5696394;Reactome: R-HSA-110320;Reactome: R-HSA-1169091;Reactome: R-HSA-2691232;Reactome: R-HSA-162588;Reactome: R-HSA-5696397;Reactome: R-HSA-450321;Reactome: R-HSA-5656169;Reactome: R-HSA-174184;Reactome: R-HSA-3785653;Reactome: R-HSA-6781827;Reactome: R-HSA-5610780;Reactome: R-HSA-9636383;Reactome: R-HSA-69017;Reactome: R-HSA-937042;Reactome: R-HSA-179409;Reactome: R-HSA-5696395	"IRAK1 recruits IKK complex";"Negative regulation of MAPK pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"APC/C:Cdc20 mediated degradation of Securin";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Stabilization of p53";"Translation initiation complex formation";"Peptide chain elongation";"Deactivation of the beta-catenin transactivating complex";"NOD1/2 Signaling Pathway";"Eukaryotic Translation Termination";"Vpu mediated degradation of CD4";"Regulation of PTEN localization";"MAPK6/MAPK4 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Fanconi Anemia Pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cyclin D associated events in G1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"E3 ubiquitin ligases ubiquitinate target proteins";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"ISG15 antiviral mechanism";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"SRP-dependent cotranslational protein targeting to membrane";"Iron uptake and transport";"APC/C:Cdc20 mediated degradation of Cyclin B";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Late endosomal microautophagy";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of FZD by ubiquitination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Senescence-Associated Secretory Phenotype (SASP)";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Oncogene Induced Senescence";"Degradation of beta-catenin by the destruction complex";"Spry regulation of FGF signaling";"Aggrephagy";"ER-Phagosome pathway";"Ub-specific processing proteases";"Degradation of DVL";"Regulation of innate immune responses to cytosolic DNA";"ER Quality Control Compartment (ERQC)";"Regulation of signaling by CBL";"EGFR downregulation";"Regulation of TP53 Degradation";"Regulation of necroptotic cell death";"InlA-mediated entry of Listeria monocytogenes into host cells";"TNFR1-induced NFkappaB signaling pathway";"Selenocysteine synthesis";"IKK complex recruitment mediated by RIP1";"SCF(Skp2)-mediated degradation of p27/p21";"p75NTR recruits signalling complexes";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Downregulation of ERBB2 signaling";"Dual Incision in GG-NER";"Negative regulation of FGFR3 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Pink/Parkin Mediated Mitophagy";"NRIF signals cell death from the nucleus";"TNFR2 non-canonical NF-kB pathway";"Glycogen synthesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"Formation of TC-NER Pre-Incision Complex";"G2/M Checkpoints";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of ERBB2:ERBB3 signaling";"Translesion synthesis by POLI";"Regulation of TNFR1 signaling";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Dual incision in TC-NER";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of RAS by GAPs";"GLI3 is processed to GLI3R by the proteasome";"Viral mRNA Translation";"Downregulation of TGF-beta receptor signaling";"Clathrin-mediated endocytosis";"Stimuli-sensing channels";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activated NOTCH1 Transmits Signal to the Nucleus";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"ABC-family proteins mediated transport";"Negative regulators of DDX58/IFIH1 signaling";"NF-kB is activated and signals survival";"Ovarian tumor domain proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of AXIN";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Metalloprotease DUBs";"TICAM1, RIP1-mediated IKK complex recruitment";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Dectin-1 mediated noncanonical NF-kB signaling";"Translesion synthesis by REV1";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of a pool of free 40S subunits";"TCF dependent signaling in response to WNT";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Translesion synthesis by POLK";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Modulation by Mtb of host immune system";"Formation of the ternary complex, and subsequently, the 43S complex";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"L13a-mediated translational silencing of Ceruloplasmin expression";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Josephin domain DUBs";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of RUNX3 expression and activity";"Amyloid fiber formation";"Processing of DNA double-strand break ends";"Negative regulation of FGFR4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Cargo recognition for clathrin-mediated endocytosis";"Circadian Clock";"NOTCH1 Intracellular Domain Regulates Transcription";"Negative regulation of MET activity";"TICAM1-dependent activation of IRF3/IRF7";"Assembly Of The HIV Virion";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Downregulation of ERBB4 signaling";"Negative regulation of FGFR1 signaling";"Peroxisomal protein import";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of TP53 Activity through Methylation";"Ubiquitin-dependent degradation of Cyclin D";"Chaperone Mediated Autophagy";"HDR through Homologous Recombination (HRR)";"Degradation of GLI2 by the proteasome";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Alpha-protein kinase 1 signaling pathway";"UCH proteinases";"Negative regulation of FGFR2 signaling";"Neddylation";"Membrane binding and targetting of GAG proteins";"DNA Damage Recognition in GG-NER";"Translesion Synthesis by POLH";"Activation of NF-kappaB in B cells";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Budding and maturation of HIV virion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Termination of translesion DNA synthesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Myoclonic epilepsy of Lafora";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Degradation of GLI1 by the proteasome";"Prevention of phagosomal-lysosomal fusion";"CDK-mediated phosphorylation and removal of Cdc6";"IRAK2 mediated activation of TAK1 complex";"APC-Cdc20 mediated degradation of Nek2A";"Formation of Incision Complex in GG-NER"
XP_054011777.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053995369.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305	"Keratan sulfate degradation";"Neutrophil degranulation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D"
XP_054011238.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053997993.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_053999483.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_054001399.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054000478.1	3	KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985;Reactome: R-HSA-913709	"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins"
XP_054000016.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_054005362.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054011397.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange"
XP_054012557.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_053997935.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_054011712.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-113501	"Polymerase switching";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_054004582.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_054014283.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054006210.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054009640.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054013187.1	8	Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-4615885	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"SUMOylation of DNA replication proteins"
XP_053996801.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054003425.1	19	Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837	"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"HSF1-dependent transactivation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases"
XP_054014183.1	6	MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis"
XP_054015726.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054013287.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054005356.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_053995764.1	3	KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619	"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI"
XP_054016550.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054001834.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054012573.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054007764.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_054001600.1	57	Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8939236;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_053995922.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054011675.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054009038.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054001794.1	4	KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis"
XP_054001323.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054011753.1	5	MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-6902	"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)"
XP_054010670.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053999295.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054000787.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054010789.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-882;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-7456;KEGG: 00520+5.4.2.8;MetaCyc: PWY-5659	"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis"
XP_053999046.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_054003047.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054015683.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054004406.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054007802.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_053996185.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054012119.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054000826.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_054006361.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_054011151.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012031.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053999731.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_054008069.1	5	Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054004502.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054013107.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_054003109.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism"
XP_053999838.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_053996120.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-75815;Reactome: R-HSA-8854050;Reactome: R-HSA-69481	"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Ubiquitin-dependent degradation of Cyclin D";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints"
XP_053997370.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_054013301.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053996563.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_053999798.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_054015305.1	10	KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484	"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)"
XP_054008676.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-111367;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_054011729.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997002.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054011637.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_054001727.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053996220.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_054002311.1	2	Reactome: R-HSA-9603798;Reactome: R-HSA-1369062	"Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis"
XP_053997953.1	7	MetaCyc: PWY-7841;Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7839;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836	"Neolacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis"
XP_054015471.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054007247.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054003130.1	2	Reactome: R-HSA-390918;Reactome: R-HSA-9033241	"Peroxisomal lipid metabolism";"Peroxisomal protein import"
XP_054008975.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_054013475.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053995247.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733	"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_054001886.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_053997396.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_054005396.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_053998382.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_054013688.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054014928.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054008690.1	15	Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-174178	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_053997776.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054003450.1	7	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"mTORC1-mediated signalling";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054003123.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex"
XP_054003174.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054015936.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053996731.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053997066.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054000312.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00030+1.1.1.49	"Glutathione metabolism";"Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Pentose phosphate pathway"
XP_054002647.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054014485.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553	"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs"
XP_054008625.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054000377.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_053997874.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053998313.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054010839.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054015693.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054005654.1	33	Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-2500257;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333	"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery"
XP_054013631.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_053999285.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053997823.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054006038.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054015355.1	3	Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2	"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism"
XP_053996133.1	5	Reactome: R-HSA-162710;Reactome: R-HSA-4719377;Reactome: R-HSA-4719360;Reactome: R-HSA-162699;Reactome: R-HSA-4717374	"Synthesis of glycosylphosphatidylinositol (GPI)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_054015635.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_054000797.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054006537.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_054009422.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054014514.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
XP_054001309.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053996046.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053996233.1	5	MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_054005903.1	5	MetaCyc: PWY-4361;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;Reactome: R-HSA-1237112;Reactome: R-HSA-111458	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"Methionine salvage pathway";"Formation of apoptosome"
XP_053999185.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054008926.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053998392.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054012844.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054008779.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_054003828.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053998963.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures"
XP_054006091.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054003259.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054005386.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054009081.1	6	Reactome: R-HSA-1369062;Reactome: R-HSA-2046106;Reactome: R-HSA-2046105;Reactome: R-HSA-390247;Reactome: R-HSA-9603798;Reactome: R-HSA-5684045	"ABC transporters in lipid homeostasis";"alpha-linolenic acid (ALA) metabolism";"Linoleic acid (LA) metabolism";"Beta-oxidation of very long chain fatty acids";"Class I peroxisomal membrane protein import";"Defective ABCD1 causes adrenoleukodystrophy (ALD)"
XP_054004294.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054003159.1	14	Reactome: R-HSA-1855204;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-500657;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11	"Synthesis of IP3 and IP4 in the cytosol";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Presynaptic function of Kainate receptors";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism"
XP_053995866.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054001736.1	10	MetaCyc: PWY-7587;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411	"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Synthesis of PA";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_054000171.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054015984.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054014751.1	13	KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308;MetaCyc: PWY-6807;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Other glycan degradation";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid metabolism";"Neutrophil degranulation";"Sphingolipid metabolism";"Sialic acid metabolism";"HS-GAG degradation";"Galactose metabolism"
XP_053997128.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053996378.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054001870.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054007074.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_053997228.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053999788.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054010634.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans"
XP_054000393.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053997859.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_054015677.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053997780.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054005679.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054004566.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054000655.1	6	MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_054011925.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054000335.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054007852.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054013158.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054006140.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054004654.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-881907	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_054013909.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054008409.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_054006591.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054014355.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253	"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_053996312.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_054013258.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054003380.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054003827.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054003699.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054008239.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054004903.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053995523.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054010532.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs"
XP_054007523.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_054014936.1	19	Reactome: R-HSA-380270;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7198;Reactome: R-HSA-380320;MetaCyc: PWY-7210;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7187;MetaCyc: PWY-7227;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7176;MetaCyc: PWY-7197;MetaCyc: PWY-7221	"Recruitment of mitotic centrosome proteins and complexes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Recruitment of NuMA to mitotic centrosomes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis"
XP_054006075.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053999063.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054005227.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054001541.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_054002089.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053999787.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053997227.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68689	"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex"
XP_054016832.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_054004066.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054016372.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054000403.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-2151201	"UCH proteinases";"HATs acetylate histones";"Transcriptional activation of mitochondrial biogenesis"
XP_054007260.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053996377.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054005321.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054013624.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053995949.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_053996171.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054007949.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054003894.1	7	MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6470;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;KEGG: 00550+2.4.1.227	"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis"
XP_054013853.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231	"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production"
XP_053998811.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_054013673.1	32	Reactome: R-HSA-112382;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161	"Formation of RNA Pol II elongation complex";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"mRNA Splicing - Minor Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation"
XP_054013930.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-69091	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Polymerase switching"
XP_053996442.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054005566.1	7	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_054016815.1	25	Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-380270;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-437239	"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"Gap junction assembly";"Recycling pathway of L1"
XP_053996335.1	8	Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-432040	"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_054014612.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_054015420.1	5	KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism";"Neutrophil degranulation"
XP_054010484.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053996875.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053996724.1	13	Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-450302;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-9645460;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-450321	"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_053998115.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054004386.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054006538.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_054016039.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053995469.1	12	Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;MetaCyc: PWY-5278	"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Selenate reduction";"Purine metabolism";"Sulfur metabolism";"Selenocompound metabolism";"Monobactam biosynthesis";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfite oxidation III"
XP_053997294.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_054006037.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054005552.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054007469.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_054005294.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054007559.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_054000838.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_054005462.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054000378.1	6	Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-201722	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Neddylation";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex"
XP_054016782.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054011358.1	5	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_054011638.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782	"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis"
XP_054003796.1	179	Reactome: R-HSA-8948747;Reactome: R-HSA-5687128;Reactome: R-HSA-168638;Reactome: R-HSA-72764;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-69231;Reactome: R-HSA-2979096;Reactome: R-HSA-6783310;Reactome: R-HSA-8866652;Reactome: R-HSA-8852276;Reactome: R-HSA-8866654;Reactome: R-HSA-8875360;Reactome: R-HSA-1799339;Reactome: R-HSA-975144;Reactome: R-HSA-1169408;Reactome: R-HSA-5675221;Reactome: R-HSA-6791226;Reactome: R-HSA-937039;Reactome: R-HSA-174154;Reactome: R-HSA-69541;Reactome: R-HSA-72706;Reactome: R-HSA-937072;Reactome: R-HSA-3769402;Reactome: R-HSA-156902;Reactome: R-HSA-5689880;Reactome: R-HSA-4641258;Reactome: R-HSA-3134975;Reactome: R-HSA-901032;Reactome: R-HSA-9615710;Reactome: R-HSA-5684264;Reactome: R-HSA-917937;Reactome: R-HSA-174048;Reactome: R-HSA-4641263;Reactome: R-HSA-9633012;Reactome: R-HSA-2559582;Reactome: R-HSA-8854050;Reactome: R-HSA-2559585;Reactome: R-HSA-69601;Reactome: R-HSA-1236974;Reactome: R-HSA-1295596;Reactome: R-HSA-195253;Reactome: R-HSA-9646399;Reactome: R-HSA-202424;Reactome: R-HSA-8863795;Reactome: R-HSA-180585;Reactome: R-HSA-5654732;Reactome: R-HSA-8849469;Reactome: R-HSA-5696400;Reactome: R-HSA-205043;Reactome: R-HSA-5668541;Reactome: R-HSA-3322077;Reactome: R-HSA-5205685;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-6804757;Reactome: R-HSA-182971;Reactome: R-HSA-5675482;Reactome: R-HSA-912631;Reactome: R-HSA-187577;Reactome: R-HSA-937041;Reactome: R-HSA-8876493;Reactome: R-HSA-5357956;Reactome: R-HSA-2408557;Reactome: R-HSA-209543;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-6782135;Reactome: R-HSA-174178;Reactome: R-HSA-5610785;Reactome: R-HSA-975956;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-192823;Reactome: R-HSA-8856828;Reactome: R-HSA-2173788;Reactome: R-HSA-2672351;Reactome: R-HSA-6782210;Reactome: R-HSA-2122948;Reactome: R-HSA-6781823;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5357905;Reactome: R-HSA-1358803;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-4641257;Reactome: R-HSA-445989;Reactome: R-HSA-2644606;Reactome: R-HSA-5689901;Reactome: R-HSA-168928;Reactome: R-HSA-168927;Reactome: R-HSA-5607761;Reactome: R-HSA-936440;Reactome: R-HSA-382556;Reactome: R-HSA-2894862;Reactome: R-HSA-5689896;Reactome: R-HSA-917729;Reactome: R-HSA-209560;Reactome: R-HSA-1236382;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-349425;Reactome: R-HSA-9637628;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-156827;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;Reactome: R-HSA-5632684;Reactome: R-HSA-110312;Reactome: R-HSA-450408;Reactome: R-HSA-532668;Reactome: R-HSA-2173791;Reactome: R-HSA-201681;Reactome: R-HSA-72689;Reactome: R-HSA-983168;Reactome: R-HSA-5655862;Reactome: R-HSA-936964;Reactome: R-HSA-9013507;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-2122947;Reactome: R-HSA-8856825;Reactome: R-HSA-400253;Reactome: R-HSA-175474;Reactome: R-HSA-9013973;Reactome: R-HSA-6807004;Reactome: R-HSA-5693607;Reactome: R-HSA-2565942;Reactome: R-HSA-977225;Reactome: R-HSA-8941858;Reactome: R-HSA-5654733;Reactome: R-HSA-68827;Reactome: R-HSA-975163;Reactome: R-HSA-975957;Reactome: R-HSA-174490;Reactome: R-HSA-110320;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-2691232;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-3785653;Reactome: R-HSA-6781827;Reactome: R-HSA-162588;Reactome: R-HSA-5696397;Reactome: R-HSA-450321;Reactome: R-HSA-5656169;Reactome: R-HSA-937042;Reactome: R-HSA-179409;Reactome: R-HSA-5696395;Reactome: R-HSA-5610780;Reactome: R-HSA-9636383;Reactome: R-HSA-69017;Reactome: R-HSA-9033241;Reactome: R-HSA-9014325;Reactome: R-HSA-6804760;Reactome: R-HSA-75815;Reactome: R-HSA-2173795;Reactome: R-HSA-1253288;Reactome: R-HSA-5654726;Reactome: R-HSA-5685942;Reactome: R-HSA-9613829;Reactome: R-HSA-975110;Reactome: R-HSA-9645460;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-2173796;Reactome: R-HSA-5654727;Reactome: R-HSA-5689603	"Regulation of PTEN localization";"MAPK6/MAPK4 signaling";"NOD1/2 Signaling Pathway";"Eukaryotic Translation Termination";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Cyclin D associated events in G1";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Fanconi Anemia Pathway";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"E3 ubiquitin ligases ubiquitinate target proteins";"InlB-mediated entry of Listeria monocytogenes into host cell";"SRP-dependent cotranslational protein targeting to membrane";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"ISG15 antiviral mechanism";"Negative regulation of MAPK pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"IRAK1 recruits IKK complex";"APC/C:Cdc20 mediated degradation of Securin";"Stabilization of p53";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Deactivation of the beta-catenin transactivating complex";"Peptide chain elongation";"Ub-specific processing proteases";"Degradation of DVL";"Regulation of innate immune responses to cytosolic DNA";"ER Quality Control Compartment (ERQC)";"Late endosomal microautophagy";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Iron uptake and transport";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of FZD by ubiquitination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Senescence-Associated Secretory Phenotype (SASP)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oncogene Induced Senescence";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"ER-Phagosome pathway";"Spry regulation of FGF signaling";"Degradation of beta-catenin by the destruction complex";"Aggrephagy";"Downstream TCR signaling";"Downregulation of ERBB2 signaling";"Vif-mediated degradation of APOBEC3G";"Negative regulation of FGFR3 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Dual Incision in GG-NER";"NRIF signals cell death from the nucleus";"TNFR2 non-canonical NF-kB pathway";"Glycogen synthesis";"Pink/Parkin Mediated Mitophagy";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of TP53 Degradation";"EGFR downregulation";"Regulation of necroptotic cell death";"Regulation of signaling by CBL";"SCF(Skp2)-mediated degradation of p27/p21";"IKK complex recruitment mediated by RIP1";"InlA-mediated entry of Listeria monocytogenes into host cells";"TNFR1-induced NFkappaB signaling pathway";"Selenocysteine synthesis";"p75NTR recruits signalling complexes";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Dual incision in TC-NER";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GLI3 is processed to GLI3R by the proteasome";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Viral mRNA Translation";"Clathrin-mediated endocytosis";"Downregulation of TGF-beta receptor signaling";"Stimuli-sensing channels";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activated NOTCH1 Transmits Signal to the Nucleus";"Formation of TC-NER Pre-Incision Complex";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Regulation of TNFR1 signaling";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Degradation of AXIN";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Metalloprotease DUBs";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"TICAM1, RIP1-mediated IKK complex recruitment";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulators of DDX58/IFIH1 signaling";"ABC-family proteins mediated transport";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Ovarian tumor domain proteases";"Endosomal Sorting Complex Required For Transport (ESCRT)";"NF-kB is activated and signals survival";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of the E3 ubiquitin ligase COP1";"Modulation by Mtb of host immune system";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Hedgehog ligand biogenesis";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"L13a-mediated translational silencing of Ceruloplasmin expression";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"Hedgehog 'on' state";"Translesion synthesis by REV1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TCF dependent signaling in response to WNT";"Formation of a pool of free 40S subunits";"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion synthesis by POLK";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Cargo recognition for clathrin-mediated endocytosis";"Circadian Clock";"Assembly Of The HIV Virion";"TICAM1-dependent activation of IRF3/IRF7";"Negative regulation of MET activity";"Processing of DNA double-strand break ends";"Regulation of PLK1 Activity at G2/M Transition";"Amyloid fiber formation";"Regulation of RUNX3 expression and activity";"Negative regulation of FGFR4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Membrane binding and targetting of GAG proteins";"Translesion Synthesis by POLH";"DNA Damage Recognition in GG-NER";"Neddylation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Myoclonic epilepsy of Lafora";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Budding and maturation of HIV virion";"Gap-filling DNA repair synthesis and ligation in GG-NER";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Termination of translesion DNA synthesis";"IRAK2 mediated activation of TAK1 complex";"APC-Cdc20 mediated degradation of Nek2A";"Formation of Incision Complex in GG-NER";"Degradation of GLI1 by the proteasome";"Prevention of phagosomal-lysosomal fusion";"CDK-mediated phosphorylation and removal of Cdc6";"Peroxisomal protein import";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Regulation of TP53 Activity through Methylation";"Ubiquitin-dependent degradation of Cyclin D";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Downregulation of ERBB4 signaling";"Negative regulation of FGFR1 signaling";"HDR through Homologous Recombination (HRR)";"Chaperone Mediated Autophagy";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Alpha-protein kinase 1 signaling pathway";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Negative regulation of FGFR2 signaling";"UCH proteinases"
XP_054000285.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053999797.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054005502.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054002099.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053995509.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-196757;Reactome: R-HSA-1474151;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;KEGG: 00670+1.5.1.3;MetaCyc: PWY-3841	"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"One carbon pool by folate";"Folate transformations II (plants)"
XP_054003376.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054009319.1	10	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Recycling pathway of L1";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection";"RSK activation";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_053997236.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475	"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054005043.1	8	Reactome: R-HSA-71336;Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-6791462;MetaCyc: PWY-5723;Reactome: R-HSA-8950505;KEGG: 00030+2.2.1.2;MetaCyc: PWY-1861	"Pentose phosphate pathway";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054006581.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054004809.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-975956;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"mTORC1-mediated signalling";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition"
XP_054014807.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054008423.1	5	Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)"
XP_054001125.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054014471.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_054016050.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054010162.1	6	Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex"
XP_053998556.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053999773.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012024.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053998466.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_054000788.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054005284.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054009538.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_054000563.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_054002892.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054004396.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054004776.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053999546.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054005184.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054003547.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054013549.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054004830.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9619483	"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs"
XP_054013959.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053998562.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053999171.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_054010971.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054011691.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054004790.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054008569.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054012531.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054008938.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-3108214	"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins"
XP_054007745.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_053999271.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_054010256.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_054004002.1	17	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination"
XP_054013208.1	13	MetaCyc: PWY-6842;MetaCyc: PWY-4061;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-2261;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112	"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate glutathione cycle";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification"
XP_054006026.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054013451.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740	"Phosphatidylinositol signaling system";"RHO GTPases activate PKNs"
XP_054005434.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053998413.1	4	MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Selenocysteine synthesis"
XP_053998747.1	14	MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_054012558.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_054011398.1	9	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054011237.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054015455.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053997104.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054011778.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054001239.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054006816.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054004912.1	9	Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108	"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_054009941.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053997204.1	13	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation"
XP_054002059.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054000708.1	2	MetaCyc: PWY-6502;Reactome: R-HSA-2393930	"8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins"
XP_054015888.1	13	KEGG: 00240+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184	"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_053999329.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054014979.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054009551.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054004977.1	8	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Recycling pathway of L1";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054003350.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054008290.1	4	Reactome: R-HSA-3899300;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710	"SUMOylation of transcription cofactors";"Chaperone Mediated Autophagy";"Aggrephagy";"Late endosomal microautophagy"
XP_054003630.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054015044.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_054009461.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054013188.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054003973.1	20	Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574;MetaCyc: PWY-7726;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-735;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7288	"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_054014385.1	5	Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-427413	"DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression"
XP_054008541.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054015283.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053999695.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054001100.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054007589.1	52	Reactome: R-HSA-167152;Reactome: R-HSA-5250924;Reactome: R-HSA-167162;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-72086;Reactome: R-HSA-749476;Reactome: R-HSA-72163;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-72165;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-72203;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-73863;Reactome: R-HSA-73776;Reactome: R-HSA-167200;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-73772	"Formation of HIV elongation complex in the absence of HIV Tat";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II HIV Promoter Escape";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"mRNA Capping";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Splicing - Major Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Minor Pathway";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase I Promoter Escape"
XP_053995589.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_054015183.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053996685.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054000493.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053996707.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_054010564.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053998343.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_053999970.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054010170.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex"
XP_054014726.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054005978.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054004356.1	11	Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-9664565	"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2 KD Mutants"
XP_054014065.1	6	Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-922;KEGG: 00900+2.7.1.36	"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis"
XP_053998492.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054014603.1	5	KEGG: 00030+4.1.2.4;MetaCyc: PWY-7180;MetaCyc: PWY-8060;Reactome: R-HSA-6798695;Reactome: R-HSA-71336	"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation";"Pentose phosphate pathway"
XP_054011040.1	52	Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-983168	"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054010196.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_054012619.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-6790901	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol"
XP_054014954.1	6	Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_054003609.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054010045.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_053996986.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054004362.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054013883.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053998164.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054007117.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054014873.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054014653.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054015112.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_054014333.1	5	Reactome: R-HSA-197264;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21	"Nicotinamide salvaging";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_054006461.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054013877.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053995961.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054003879.1	3	Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053995217.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054013657.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_053997513.1	12	KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4	"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism"
XP_054008728.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-418592	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1"
XP_054008280.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_054007272.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054015898.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053999303.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054007441.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054002922.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054010234.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054016360.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_054001150.1	3	MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6	"Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism"
XP_054016025.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_054015738.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054007172.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054010404.1	52	Reactome: R-HSA-76071;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-9018519;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-167287;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-6782135;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-203927;Reactome: R-HSA-167162;Reactome: R-HSA-5250924;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-5617472;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-1834949	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Estrogen-dependent gene expression";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Dual incision in TC-NER";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II HIV Promoter Escape";"B-WICH complex positively regulates rRNA expression";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA"
XP_054012960.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_054001250.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;MetaCyc: PWY-7221	"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis"
XP_054002802.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053996329.1	9	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_054003300.1	2	Reactome: R-HSA-196783;KEGG: 00770+6.3.2.5	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_054003854.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054013893.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy"
XP_054003674.1	12	Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-2660826;Reactome: R-HSA-75893;Reactome: R-HSA-2122948;Reactome: R-HSA-982772;Reactome: R-HSA-177929	"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Growth hormone receptor signaling";"Signaling by EGFR"
XP_054013835.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053996996.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531	"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_054013989.1	5	KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_054014629.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_054008489.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024096;Reactome: R-HSA-2024101	"MPS II - Hunter syndrome";"HS-GAG degradation";"CS/DS degradation"
XP_054008125.1	44	Reactome: R-HSA-112409;Reactome: R-HSA-5654726;Reactome: R-HSA-162658;Reactome: R-HSA-2559580;Reactome: R-HSA-375165;Reactome: R-HSA-198753;Reactome: R-HSA-9627069;Reactome: R-HSA-2559582;Reactome: R-HSA-3371453;Reactome: R-HSA-2559585;Reactome: R-HSA-74749;Reactome: R-HSA-2871796;Reactome: R-HSA-1295596;Reactome: R-HSA-5654727;Reactome: R-HSA-5673001;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-8939211;Reactome: R-HSA-879415;Reactome: R-HSA-5663213;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-2029482;Reactome: R-HSA-5674135;Reactome: R-HSA-202670;Reactome: R-HSA-5675221;Reactome: R-HSA-445144;Reactome: R-HSA-9634638;Reactome: R-HSA-6802946;Reactome: R-HSA-5654733;Reactome: R-HSA-5668599;Reactome: R-HSA-456926;KEGG: 04150+2.7.11.24;Reactome: R-HSA-444257;Reactome: R-HSA-5674499;Reactome: R-HSA-881907;Reactome: R-HSA-6811558;Reactome: R-HSA-170968;Reactome: R-HSA-8940973;Reactome: R-HSA-8943724;Reactome: R-HSA-9635465;Reactome: R-HSA-5654732;Reactome: R-HSA-450341;Reactome: R-HSA-982772	"RAF-independent MAPK1/3 activation";"Negative regulation of FGFR1 signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Oxidative Stress Induced Senescence";"NCAM signaling for neurite out-growth";"ERK/MAPK targets";"Regulation of the apoptosome activity";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of HSF1-mediated heat shock response";"Oncogene Induced Senescence";"Signal attenuation";"FCERI mediated MAPK activation";"Spry regulation of FGF signaling";"Negative regulation of FGFR2 signaling";"RAF/MAP kinase cascade";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ESR-mediated signaling";"Advanced glycosylation endproduct receptor signaling";"RHO GTPases Activate WASPs and WAVEs";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Regulation of actin dynamics for phagocytic cup formation";"MAP2K and MAPK activation";"ERKs are inactivated";"Negative regulation of MAPK pathway";"Signal transduction by L1";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR4 signaling";"RHO GTPases Activate NADPH Oxidases";"Thrombin signalling through proteinase activated receptors (PARs)";"mTOR signaling pathway";"RSK activation";"Negative feedback regulation of MAPK pathway";"Gastrin-CREB signalling pathway via PKC and MAPK";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Frs2-mediated activation";"RUNX2 regulates osteoblast differentiation";"Regulation of PTEN gene transcription";"Suppression of apoptosis";"Negative regulation of FGFR3 signaling";"Activation of the AP-1 family of transcription factors";"Growth hormone receptor signaling"
XP_053999986.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_054010186.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054004899.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053998482.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"RHO GTPases Activate Formins"
XP_054015135.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling"
XP_054012508.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054003017.1	24	Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-190861	"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"Recycling pathway of L1";"Gap junction assembly"
XP_053997470.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054015193.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053996695.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054013131.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054005154.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054001459.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053995599.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription"
XP_053998586.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054001569.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_054000758.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054003518.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054005592.1	12	MetaCyc: PWY-2821;MetaCyc: PWY-1187;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-6842;Reactome: R-HSA-71240;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-6936	"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Glutathione-mediated detoxification II";"Tryptophan catabolism";"Tryptophan metabolism";"Cysteine and methionine metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)"
XP_054004013.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053997592.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054015293.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_053995189.1	6	KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053995425.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-389960	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Recycling pathway of L1";"Gap junction assembly";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC"
XP_054006805.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054016041.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054008347.1	5	Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;MetaCyc: PWY-5188;Reactome: R-HSA-189451	"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis"
XP_054009637.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054009729.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054007289.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054010164.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054011846.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_053995289.1	8	KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_053998296.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_053999964.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054012930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998045.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039	"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex"
XP_054000505.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053998270.1	6	KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1	"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms"
XP_054006431.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_054003882.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168	"Neutrophil degranulation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053998170.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054010343.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_053998564.1	14	KEGG: 00670+2.1.2.1;MetaCyc: PWY-2161;MetaCyc: PWY-3661;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-181;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1;MetaCyc: PWY-1622	"One carbon pool by folate";"Folate polyglutamylation";"Glycine betaine degradation I";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Folate transformations I";"Metabolism of folate and pterines";"Photorespiration ";"Glyoxylate and dicarboxylate metabolism";"Folate transformations II (plants)";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism";"Formaldehyde assimilation I (serine pathway)"
XP_053995931.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053998454.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054006626.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
XP_054006201.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054005504.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008576.1	9	Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_054012909.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259	"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes"
XP_054001539.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_054008845.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054011537.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054008743.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054000116.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_054016784.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054009488.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_054007480.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_054009990.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053995998.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054002786.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_054013865.1	2	Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_054008241.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation"
XP_054005643.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054008472.1	5	KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053998479.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-3371453	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response"
XP_054015861.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054012481.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054008590.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054013024.1	5	Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_053996444.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054014578.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053998328.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_054012549.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_054004079.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-71403	"Mitochondrial protein import";"Citric acid cycle (TCA cycle)"
XP_053997818.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_054005818.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway"
XP_054003892.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054009201.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_054005292.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054001269.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054005554.1	5	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-201722	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053997292.1	3	Reactome: R-HSA-5368286;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9	"Mitochondrial translation initiation";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate"
XP_054002957.1	5	MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis"
XP_054016359.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_054006729.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054011167.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_054014614.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_054003118.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053996964.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054002884.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053998186.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_054012208.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053996722.1	13	Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-450302;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-5607764;Reactome: R-HSA-5357956;Reactome: R-HSA-975163;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-9645460;Reactome: R-HSA-937042	"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"activated TAK1 mediates p38 MAPK activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"CLEC7A (Dectin-1) signaling";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex"
XP_054012491.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054013598.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054000945.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054008580.1	13	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Thermogenesis"
XP_054014093.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054007517.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054006151.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054004332.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054004965.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054004652.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-881907	"G alpha (q) signalling events";"Peptide ligand-binding receptors";"Gastrin-CREB signalling pathway via PKC and MAPK"
XP_054006251.1	13	Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054002796.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054001940.1	12	Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-5250924;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Notch-HLH transcription pathway";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_053998404.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_054004817.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054009498.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_054007988.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054015078.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_054002770.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054012687.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054006855.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054002689.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_054006753.1	17	Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-75955;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167287;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418	"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex"
XP_054001460.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054016323.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054010534.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053997711.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054000465.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_054015577.1	24	Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467	"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Cilium Assembly";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs"
XP_053995572.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_054006488.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053999915.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-426496	"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Estrogen-dependent gene expression";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs"
XP_053998484.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-3232118;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"SUMOylation of transcription factors";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_054010215.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_054014029.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054004027.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054011349.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism"
XP_054006138.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053996246.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_054007259.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054011668.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_053995259.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054003617.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_053996095.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_054005594.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_054016680.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_054012785.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_054003866.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_054006777.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_053996146.1	7	Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III"
XP_054016779.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_054016399.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054012607.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_054005152.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054011419.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724	"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription"
XP_054001845.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-8949215	"Ub-specific processing proteases";"Mitochondrial calcium ion transport"
XP_054012451.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054007721.1	10	Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-917729	"Inhibition of membrane repair";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053998532.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054006540.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_054014053.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Intraflagellar transport";"MHC class II antigen presentation"
XP_054004094.1	12	MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis";"Gluconeogenesis"
XP_054000071.1	5	Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921	"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation"
XP_054013057.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054016806.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054015114.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_054007560.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_054006793.1	2	Reactome: R-HSA-446199;Reactome: R-HSA-4755609	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59"
XP_054007174.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054010402.1	37	Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-204005;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-983170;Reactome: R-HSA-3232142	"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"COPII-mediated vesicle transport";"Transcriptional regulation by small RNAs";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of ubiquitinylation proteins"
XP_054016754.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054009458.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054010132.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053997028.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching"
XP_054006833.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_054006735.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2173788;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-2500257	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Downregulation of TGF-beta receptor signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"Resolution of Sister Chromatid Cohesion"
XP_054007450.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_054005028.1	6	Reactome: R-HSA-5654693;Reactome: R-HSA-5654700;Reactome: R-HSA-5654712;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-9028731	"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR4 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"Activated NTRK2 signals through FRS2 and FRS3"
XP_054005527.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054002973.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054001241.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053997527.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053995274.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053995223.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054000533.1	7	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-2029485	"Synthesis of PA";"Synthesis of PG";"Choline biosynthesis III";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis"
XP_053998621.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054009067.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_054012188.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054002924.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_054012733.1	5	KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_053999033.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_054006820.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_053999246.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events"
XP_054016389.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053996616.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054000263.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053999095.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"RHO GTPases Activate Formins"
XP_054007400.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054002854.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_053998156.1	6	Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163	"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway"
XP_054012893.1	12	Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416476	"DCC mediated attractive signaling";"Rho GTPase cycle";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"G alpha (q) signalling events"
XP_054001525.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule"
XP_054009397.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_054016862.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054012989.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_053998256.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054012131.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_054010466.1	34	Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5663220;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180746	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transcriptional regulation by small RNAs";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"RHO GTPases Activate Formins";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein"
XP_054014003.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_053999571.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054002017.1	6	MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807	"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism"
XP_054013508.1	8	MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2	"ATP biosynthesis";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Photosynthesis";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Oxidative phosphorylation"
XP_054004364.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054012019.1	9	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-110314;Reactome: R-HSA-5696395	"Neddylation";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of Incision Complex in GG-NER"
XP_054010645.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054003411.1	19	Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736	"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors"
XP_054013007.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054008269.1	5	Reactome: R-HSA-73621;MetaCyc: PWY-5532;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;KEGG: 00983+2.4.2.3	"Pyrimidine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_054005847.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_054016856.1	5	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of the pre-replicative complex"
XP_054004914.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_054012198.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054006568.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6362;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_053996365.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053997202.1	13	Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662	"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism"
XP_054015503.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054005202.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054001580.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_054001611.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_053995958.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_054005432.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054002879.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012657.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054005345.1	2	Reactome: R-HSA-1650814;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation"
XP_054003764.1	33	KEGG: 00830+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-6342;MetaCyc: PWY-5082;MetaCyc: PWY-6871;MetaCyc: PWY-7111;MetaCyc: PWY-7118;MetaCyc: PWY-5480;MetaCyc: PWY-7798;KEGG: 00010+1.1.1.1;KEGG: 00350+1.1.1.1;MetaCyc: PWY-5076;MetaCyc: PWY-6313;KEGG: 00626+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5079;MetaCyc: PWY-3162;MetaCyc: PWY-7013;MetaCyc: PWY-5486;MetaCyc: PWY-1801;MetaCyc: PWY-6333;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7396;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6587;MetaCyc: PWY-5078;Reactome: R-HSA-71384;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5751;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6802;KEGG: 00625+1.1.1.1	"Retinol metabolism";"L-valine degradation II";"Noradrenaline and adrenaline degradation";"L-methionine degradation III";"3-methylbutanol biosynthesis (engineered)";"Pyruvate fermentation to isobutanol (engineered)";"Chitin degradation to ethanol";"Pyruvate fermentation to ethanol I";"Protein S-nitrosylation and denitrosylation";"Glycolysis / Gluconeogenesis";"Tyrosine metabolism";"L-leucine degradation III";"Serotonin degradation";"Naphthalene degradation";"Glycine, serine and threonine metabolism";"Methane metabolism";"L-phenylalanine degradation III";"L-tryptophan degradation V (side chain pathway)";"(S)-propane-1,2-diol degradation";"Pyruvate fermentation to ethanol II";"Formaldehyde oxidation II (glutathione-dependent)";"Acetaldehyde biosynthesis I";"alpha-Linolenic acid metabolism";"Butanol and isobutanol biosynthesis (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol III";"L-isoleucine degradation II";"Ethanol oxidation";"Drug metabolism - cytochrome P450";"Phenylethanol biosynthesis";"Fatty acid degradation";"Salidroside biosynthesis";"Chloroalkane and chloroalkene degradation"
XP_053995548.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_054006281.1	14	Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862	"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Polymerase switching";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK"
XP_054009540.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053998427.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054003341.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054007548.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_053997536.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054015042.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054012658.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054003843.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054012878.1	11	Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"G alpha (i) signalling events";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_054009175.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053996163.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054005364.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054000867.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054010869.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053996263.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054006457.1	7	Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054002199.1	3	KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067;Reactome: R-HSA-3322077	"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis"
XP_054000616.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054004847.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054012197.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054006567.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054001910.1	7	Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750	"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6"
XP_054009871.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054005143.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053998428.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_054007547.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_054011714.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054000915.1	9	MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-6703;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5663	"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I"
XP_054005036.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054002490.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_054009398.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_053995390.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054012124.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins"
XP_054007689.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054009778.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054015316.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053995689.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_054014644.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163615	"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation"
XP_054001752.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054000932.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997084.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054000365.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054000020.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054014042.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_054011941.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_054005914.1	6	MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6317	"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Defective GALT can cause Galactosemia";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)"
XP_053998933.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054011551.1	6	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8949275;Reactome: R-HSA-186797;Reactome: R-HSA-1474228;Reactome: R-HSA-216083	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"RUNX3 Regulates Immune Response and Cell Migration";"Signaling by PDGF";"Degradation of the extracellular matrix";"Integrin cell surface interactions"
XP_054012391.1	9	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway"
XP_054014503.1	9	KEGG: 00350+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;Reactome: R-HSA-8963684	"Tyrosine metabolism";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Tyrosine catabolism"
XP_054010056.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053999071.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_054011461.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178	"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_054012519.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054007376.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053995836.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_054002018.1	6	Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;KEGG: 00760+6.3.1.5	"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism"
XP_054008782.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_054001766.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_053998304.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053996414.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054014463.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_054012061.1	5	Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;MetaCyc: PWY-7511	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Protein ubiquitination"
XP_054011501.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_054006871.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054013058.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054006040.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053998032.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053998920.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_054000571.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_054000719.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054010717.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_054003469.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053998354.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054008211.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_054004152.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054005613.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053995894.1	8	Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_054012187.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054010772.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_054007060.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054010963.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054002425.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054009068.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054006175.1	6	KEGG: 00520+5.4.2.3;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation"
XP_054007325.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054003949.1	10	MetaCyc: PWY-6527;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-6397	"Stachyose degradation";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Galactose catabolism";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_053997528.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054008713.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054001090.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053999520.1	6	Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-73762	"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation"
XP_054001864.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054004266.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_054005027.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053999263.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37	"DNA methylation";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism"
XP_054015029.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_053997027.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_054009457.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054000033.1	26	Reactome: R-HSA-2644606;Reactome: R-HSA-1368082;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-8866907;Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-9013695;Reactome: R-HSA-3371568;Reactome: R-HSA-2122947;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-5621575;Reactome: R-HSA-5617472;Reactome: R-HSA-3134973;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-1234158;Reactome: R-HSA-9614657;Reactome: R-HSA-933541	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RORA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH4 Intracellular Domain Regulates Transcription";"Attenuation phase";"NOTCH1 Intracellular Domain Regulates Transcription";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"CD209 (DC-SIGN) signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation"
XP_054008372.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_054009226.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_054007786.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_054001348.1	26	Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-380320	"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"Recycling pathway of L1";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_054003574.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-112382	"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex"
XP_054008832.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_054003523.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053998839.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_054004028.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054014529.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053998985.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_054013122.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053996533.1	11	MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;MetaCyc: PWY-6606;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-6999;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6538;MetaCyc: PWY-6608	"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Theophylline degradation";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)";"Guanosine nucleotides degradation III"
XP_054012608.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_053996595.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053997094.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054006778.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_054016239.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_054011816.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054005094.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053997860.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72649	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation"
XP_054016011.1	33	Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168276	"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways"
XP_054007699.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054016409.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053995699.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054007827.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_054005692.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949664	"Mitochondrial protein import";"Processing of SMDT1"
XP_054006137.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054010366.1	6	Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_054004292.1	5	Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360	"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell"
XP_054008080.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054014593.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054009510.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_054009681.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054007518.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053998394.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054012842.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053997315.1	11	Reactome: R-HSA-2871796;Reactome: R-HSA-6796648;Reactome: R-HSA-9018519;Reactome: R-HSA-8862803;Reactome: R-HSA-450341;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8943724;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408	"FCERI mediated MAPK activation";"TP53 Regulates Transcription of DNA Repair Genes";"Estrogen-dependent gene expression";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Activation of the AP-1 family of transcription factors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of PTEN gene transcription";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation"
XP_053998774.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_054013597.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054003599.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054000444.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_053995623.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;MetaCyc: PWY-6978;MetaCyc: PWY-5871;MetaCyc: PWY-6708	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)"
XP_053998606.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054002130.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054001050.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_054012475.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383	"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation"
XP_054006487.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-422356;Reactome: R-HSA-5607763	"PLC beta mediated events";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_054010632.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083628	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_053995854.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054007854.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053995674.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053997079.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054012688.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054002230.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)"
XP_054015077.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054000055.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054004818.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054007072.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054007987.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054013524.1	7	MetaCyc: PWY-6351;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660499	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane"
XP_054003441.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148	"Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053998880.1	4	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_053998327.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_054010615.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_053998759.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054003272.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054002548.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471	"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"LDL remodeling";"Chylomicron assembly";"Scavenging by Class H Receptors";"LDL clearance";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"VLDL assembly";"Chylomicron remodeling";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors"
XP_054011610.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054004711.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-201722;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054014577.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054002047.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053996945.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662	"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism"
XP_054003172.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054008360.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6814122	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Signal transduction by L1";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Synthesis of PC";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053996555.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054012207.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054008766.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_054009424.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054015093.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054011168.1	13	KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-5497;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-2161;MetaCyc: PWY-6613	"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"One carbon pool by folate";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Folate polyglutamylation";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate"
XP_054003117.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054010916.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-9656256;Reactome: R-HSA-5649702;Reactome: R-HSA-9656255;Reactome: R-HSA-110329	"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Processing";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Defective OGG1 Substrate Binding";"Cleavage of the damaged pyrimidine"
XP_054015035.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054004113.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054005332.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054005965.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_054012107.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_053997652.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_054007659.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1"
XP_053996646.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823	"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex"
XP_054011268.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054002828.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053995997.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054009487.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053997004.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054012698.1	17	Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397	"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_054001211.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_054008076.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054008418.1	12	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Thermogenesis"
XP_054001967.1	5	MetaCyc: PWY-6277;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_054015992.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054012157.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054005602.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054016499.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054010748.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_054011449.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556	"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport"
XP_054014583.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054001447.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-381038	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes"
XP_054001713.1	25	Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-381771;Reactome: R-HSA-163359;Reactome: R-HSA-500657;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-9009391	"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Glucagon signaling in metabolic regulation";"Presynaptic function of Kainate receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"Ca2+ pathway";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Extra-nuclear estrogen signaling"
XP_054008090.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_054004643.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_053998336.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054007630.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054002450.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054007804.1	6	MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_054006473.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-422356	"PLC beta mediated events";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ion homeostasis";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion"
XP_054009638.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_054008348.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695	"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation"
XP_054007762.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053995973.1	6	KEGG: 00052+3.5.1.25;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-7077;MetaCyc: PWY-7395	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"D-galactosamine and N-acetyl-D-galactosamine degradation"
XP_054001792.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054002223.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054005769.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-416476;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659	"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"G alpha (q) signalling events";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin-7 signaling";"RET signaling"
XP_053998545.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054004504.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054011319.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054001317.1	4	Reactome: R-HSA-446199;Reactome: R-HSA-4755609;MetaCyc: PWY-6129;KEGG: 00900+2.5.1.87	"Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Terpenoid backbone biosynthesis"
XP_053998955.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_054016276.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054012631.1	3	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III"
XP_054011240.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053995756.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054016176.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054007756.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes"
XP_054014265.1	2	Reactome: R-HSA-9029569;Reactome: R-HSA-804914	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids"
XP_054015139.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053996827.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_053996380.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054013015.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing"
XP_054014806.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054009084.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_054004291.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054016822.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_053997778.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054011104.1	7	Reactome: R-HSA-73817;Reactome: R-HSA-6798695;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;MetaCyc: PWY-7221;MetaCyc: PWY-5695	"Purine ribonucleoside monophosphate biosynthesis";"Neutrophil degranulation";"Adenosine nucleotides degradation I";"Purine metabolism";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation"
XP_054000274.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054016053.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054006094.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053997237.1	9	Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237	"HS-GAG degradation";"HS-GAG biosynthesis";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2"
XP_054013686.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_054012070.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054002663.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040	"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"D-Alanine metabolism";"Ansatrienin biosynthesis"
XP_054001455.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054005398.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_054012841.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054009682.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_054013799.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054012096.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism"
XP_053999796.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_054010631.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054004950.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054003837.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_054013379.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_054012245.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_054003377.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054007071.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054013985.1	5	Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_054008485.1	5	MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922	"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)"
XP_053998122.1	2	KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201	"Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis"
XP_054012145.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_054003271.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054003442.1	7	Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257	"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion"
XP_054016029.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis"
XP_054001183.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054006027.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054003171.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054003956.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054015100.1	5	KEGG: 00533+2.4.1.68;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;MetaCyc: PWY-7426;Reactome: R-HSA-975578	"Glycosaminoglycan biosynthesis - keratan sulfate";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_054010157.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054009741.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_054005175.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053996060.1	34	Reactome: R-HSA-167158;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-69231;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-69202;Reactome: R-HSA-113418;Reactome: R-HSA-69273;Reactome: R-HSA-69656	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin D associated events in G1";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Cyclin E associated events during G1/S transition";"Formation of the Early Elongation Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry"
XP_054015430.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054001283.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053996325.1	9	KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054004397.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054008153.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054004238.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052	"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion"
XP_054008420.1	12	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Thermogenesis"
XP_054013920.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_053997040.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion"
XP_054004408.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053998557.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_053999048.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053998467.1	2	KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_054003724.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054008253.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_054013354.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054013634.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_054015991.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054011513.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054008433.1	2	Reactome: R-HSA-1369007;Reactome: R-HSA-5683371	"Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)"
XP_054013933.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054014069.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_054004067.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054007414.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053996376.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_054013995.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053998008.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_054012615.1	6	MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499	"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane"
XP_054008103.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_054003605.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_054014937.1	19	MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;Reactome: R-HSA-380270;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380320;MetaCyc: PWY-7205;MetaCyc: PWY-6545;MetaCyc: PWY-7220	"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II"
XP_054006848.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005226.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054013304.1	8	KEGG: 00790+1.14.16.2;MetaCyc: PWY-5394;MetaCyc: PWY-5049;MetaCyc: PWY-6133;MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2	"Folate biosynthesis";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II";"(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis";"Catecholamine biosynthesis";"Tyrosine metabolism"
XP_054013850.1	3	Reactome: R-HSA-264870;Reactome: R-HSA-6798695;Reactome: R-HSA-6794361	"Caspase-mediated cleavage of cytoskeletal proteins";"Neutrophil degranulation";"Neurexins and neuroligins"
XP_054013670.1	11	MetaCyc: PWY-882;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-6992	"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation"
XP_054003063.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053999786.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053997388.1	9	Reactome: R-HSA-416476;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-6351	"G alpha (q) signalling events";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_054015250.1	17	MetaCyc: PWY-6608;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;MetaCyc: PWY-7179;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-6609;Reactome: R-HSA-74259;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-4202;MetaCyc: PWY-6644	"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Purine salvage";"Pyrimidine metabolism";"Neutrophil degranulation";"Guanine and guanosine salvage";"Adenine and adenosine salvage III";"Purine catabolism";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis"
XP_054007585.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054001738.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054000109.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_054015423.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054015474.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054000439.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_054009613.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054006243.1	3	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109	"Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis"
XP_054006036.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054014862.1	10	Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695	"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_054004900.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_054010842.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054013428.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_054008928.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054014690.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054006143.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_054001791.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053996048.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054004387.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054004820.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054001831.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054007761.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054014389.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_054012632.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054014856.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_054001293.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054012352.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_054010475.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878	"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054005567.1	7	Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16	"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_054007263.1	6	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054000400.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054001235.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054015459.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054002964.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054000230.1	3	Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-110320	"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH"
XP_054001405.1	5	Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757	"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation"
XP_054012034.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_053999734.1	3	Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification"
XP_054007520.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053999060.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054005068.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054002055.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053999894.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053997068.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053997742.1	7	KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054004307.1	4	KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7394;MetaCyc: PWY-7849	"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin II";"Urate conversion to allantoin III"
XP_053995749.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_054013890.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy"
XP_054009817.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-6781823;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-73772	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Promoter Escape"
XP_054004498.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054016083.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053999659.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054013876.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_054013336.1	14	MetaCyc: PWY-5484;KEGG: 00010+4.2.1.11;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-1622;MetaCyc: PWY-2221;MetaCyc: PWY-6886;MetaCyc: PWY-6901;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7124;MetaCyc: PWY-7218	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Rubisco shunt";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Ethylene biosynthesis V (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_053995216.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_054016767.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_054009872.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_053996804.1	11	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-2132295	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"MHC class II antigen presentation"
XP_054008642.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005473.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827	"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_053996630.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054007116.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053997473.1	6	MetaCyc: PWY-5067;MetaCyc: PWY-7900;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;Reactome: R-HSA-189085	"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch biosynthesis";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_054001229.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054013545.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053998587.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054016244.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054012006.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054013709.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_054005681.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053999017.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_054011942.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_054003016.1	24	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-9619483;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Recycling pathway of L1";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"Activation of AMPK downstream of NMDARs";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly"
XP_054008183.1	9	Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-2871809;Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-2029482;Reactome: R-HSA-5218920;Reactome: R-HSA-4420097	"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"FCERI mediated Ca+2 mobilization";"GPVI-mediated activation cascade";"NRAGE signals death through JNK";"Rho GTPase cycle";"Regulation of actin dynamics for phagocytic cup formation";"VEGFR2 mediated vascular permeability";"VEGFA-VEGFR2 Pathway"
XP_054014870.1	10	Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-1912408	"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Pre-NOTCH Transcription and Translation"
XP_054000931.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054014330.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_054011321.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_054003986.1	9	MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;Reactome: R-HSA-1483166	"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_054000425.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_053999072.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054012772.1	4	Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339	"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane"
XP_054000189.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_054010187.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054006602.1	6	MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system"
XP_054012392.1	9	Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054002146.1	3	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway"
XP_053998918.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054002095.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053999300.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection"
XP_054004101.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053995505.1	2	Reactome: R-HSA-6804758;Reactome: R-HSA-3214847	"Regulation of TP53 Activity through Acetylation";"HATs acetylate histones"
XP_054008781.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_054001153.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_054002246.1	7	Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6724;MetaCyc: PWY-5941;MetaCyc: PWY-6737	"Neutrophil degranulation";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation II";"Glycogen degradation II";"Starch degradation V"
XP_054015180.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_054007646.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053998031.1	10	KEGG: 05170+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;Reactome: R-HSA-1660499;Reactome: R-HSA-9027276;KEGG: 00562+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153	"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"Synthesis of PIPs at the plasma membrane";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Inositol phosphate metabolism";"Human papillomavirus infection";"Phosphatidylinositol signaling system"
XP_054008112.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054006872.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5687128	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"MAPK6/MAPK4 signaling"
XP_053999762.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053999973.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054006965.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054006652.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_054010173.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_054005638.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis"
XP_054008212.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_053995465.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054016035.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054004976.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053997638.1	10	Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-72695;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9648895;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Response of EIF2AK1 (HRI) to heme deficiency";"Ribosomal scanning and start codon recognition"
XP_054015280.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_054001433.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054007465.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054007555.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_054001103.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054012664.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054000572.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_053995945.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-606279	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054008738.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054007945.1	5	Reactome: R-HSA-199220;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6012;MetaCyc: PWY-6012-1;MetaCyc: PWY-6289	"Vitamin B5 (pantothenate) metabolism";"Pantothenate and CoA biosynthesis";"Acyl carrier protein metabolism";"Acyl carrier protein activation";"Petrobactin biosynthesis"
XP_054013327.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_054013759.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054012056.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054010771.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_053998573.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532	"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer"
XP_054008898.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054004753.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054011236.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054011043.1	52	Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764	"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling"
XP_054016819.1	3	Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine"
XP_054010338.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053996987.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion"
XP_054010658.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054012869.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054000299.1	4	Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043	"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events"
XP_054008371.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054014886.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053996300.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_054010197.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_054015125.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051	"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I"
XP_053997487.1	5	Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_054000199.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production"
XP_054008405.1	13	MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes"
XP_054013905.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054016614.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054015901.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054014359.1	5	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_054004729.1	7	MetaCyc: PWY-4702;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25	"Phytate degradation I";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system"
XP_054004357.1	11	Reactome: R-HSA-9664565;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-2219530;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986	"Signaling by ERBB2 KD Mutants";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2"
XP_054014639.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation"
XP_054003353.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_054003633.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054013825.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054013774.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_054016012.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054003695.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_054010198.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_054005990.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_054005488.1	8	KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1	"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism"
XP_053997990.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054016577.1	8	KEGG: 00710+5.3.1.6;Reactome: R-HSA-6791461;MetaCyc: PWY-5723;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861;Reactome: R-HSA-5659996;KEGG: 00051+5.3.1.6;Reactome: R-HSA-71336	"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of RU5P to R5P";"Rubisco shunt";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of R5P to RU5P";"Fructose and mannose metabolism";"Pentose phosphate pathway"
XP_054011809.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054001807.1	6	Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_054005753.1	19	Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-8964616;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-194840;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-114604;Reactome: R-HSA-8950505;Reactome: R-HSA-4420097;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467	"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"G beta:gamma signalling through CDC42";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"Rho GTPase cycle";"CD28 dependent Vav1 pathway";"EGFR downregulation";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs"
XP_054015323.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_053997855.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_054016078.1	19	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-72764;Reactome: R-HSA-3214858;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-9633012	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Eukaryotic Translation Termination";"RMTs methylate histone arginines";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054016416.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054015600.1	4	Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER"
XP_054010657.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054000659.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_054015374.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054008775.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257	"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion"
XP_054008333.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041	"Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle"
XP_054013234.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_054008824.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_054008395.1	6	MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5744	"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation"
XP_054014728.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_054004638.1	5	KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-5514	"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_054005151.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053997151.1	4	KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_054009643.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_054003155.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054010375.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054009282.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_054010835.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054007722.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-917729;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-432720	"Ub-specific processing proteases";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Inhibition of membrane repair";"Negative regulation of MET activity";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis"
XP_053999289.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054011002.1	2	KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175	"Glycine, serine and threonine metabolism";"Threonine catabolism"
XP_054015639.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054000854.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054015727.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2122948	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_054007964.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination"
XP_054014901.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054005637.1	7	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054010795.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054015359.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_054002520.1	3	Reactome: R-HSA-8866654;MetaCyc: PWY-7511;Reactome: R-HSA-110314	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053996299.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054016535.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-9020702	"Neutrophil degranulation";"Interleukin-1 signaling"
XP_054006464.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054011370.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053999425.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236	"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054007055.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_054011830.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_054000987.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054000072.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921	"Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation"
XP_053998024.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054012466.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167287	"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery"
XP_054003483.1	7	MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule"
XP_054010131.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054011776.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011396.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_054012556.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_054015886.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054008897.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054016740.1	3	Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801	"Glutathione conjugation";"Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)"
XP_054013328.1	3	Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807	"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)"
XP_054008737.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_054008629.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_054002344.1	14	Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-167246	"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript"
XP_054001242.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054007444.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054008979.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)"
XP_053997010.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054012506.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054014290.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053999476.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends"
XP_054004473.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_053999517.1	6	Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863	"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination"
XP_054016861.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054008385.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054000756.1	30	Reactome: R-HSA-195253;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-917937;Reactome: R-HSA-2894862;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761;Reactome: R-HSA-2644607;Reactome: R-HSA-5610780;Reactome: R-HSA-2122947;Reactome: R-HSA-400253;Reactome: R-HSA-1170546;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-69231;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-202424	"Degradation of beta-catenin by the destruction complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of GLI1 by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Circadian Clock";"Prolactin receptor signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Cyclin D associated events in G1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Downstream TCR signaling"
XP_053998588.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054016265.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802948	"MAP2K and MAPK activation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants"
XP_054000804.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053998917.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054011725.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054016165.1	6	MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122	"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis"
XP_054010188.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex"
XP_054006504.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053997980.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054003412.1	19	Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_054005498.1	8	KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1	"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism"
XP_053995810.1	4	Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00410+4.1.1.9	"Peroxisomal protein import";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids";"beta-Alanine metabolism"
XP_054005201.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-191859	"RNA polymerase II transcribes snRNA genes";"snRNP Assembly"
XP_054008603.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901	"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs"
XP_054004497.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054007810.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054013270.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054008065.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054003435.1	19	Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-399719	"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors"
XP_053997101.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054013170.1	5	Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-165181;Reactome: R-HSA-1632852	"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Inhibition of TSC complex formation by PKB";"Macroautophagy"
XP_054004308.1	4	MetaCyc: PWY-7849;MetaCyc: PWY-7394;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97	"Urate conversion to allantoin III";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Purine metabolism"
XP_054008954.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054003493.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054016583.1	13	Reactome: R-HSA-5358346;Reactome: R-HSA-8876725;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-9646399;Reactome: R-HSA-6798695;Reactome: R-HSA-5362768;Reactome: R-HSA-5689896;Reactome: R-HSA-8866654;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-110320;Reactome: R-HSA-3371511	"Hedgehog ligand biogenesis";"Protein methylation";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"Aggrephagy";"Neutrophil degranulation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Ovarian tumor domain proteases";"E3 ubiquitin ligases ubiquitinate target proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Translesion Synthesis by POLH";"HSF1 activation"
XP_054003342.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_054013196.1	6	Reactome: R-HSA-446199;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33	"Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis"
XP_054001857.1	9	Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852	"Regulation of PTEN gene transcription";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Neutrophil degranulation";"Macroautophagy"
XP_054004681.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053997805.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054006182.1	8	KEGG: 04660+3.1.3.16;KEGG: 00564+3.1.3.27;KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 05235+3.1.3.16;Reactome: R-HSA-1483148	"T cell receptor signaling pathway";"Glycerophospholipid metabolism";"Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Synthesis of PG"
XP_053999299.1	7	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054015041.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054009464.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_054001984.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_054004388.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054006536.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_054011306.1	11	Reactome: R-HSA-2173796;Reactome: R-HSA-8941856;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-72163;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RUNX3 regulates NOTCH signaling";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"mRNA Splicing - Major Pathway";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription"
XP_054016042.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054014250.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_053997181.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053996047.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054008927.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_054003429.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-936837;Reactome: R-HSA-9022692	"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity"
XP_054016644.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054000376.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_054005281.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054000836.1	4	KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)"
XP_054014474.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression"
XP_053998960.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures"
XP_054000796.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053997067.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054010803.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_054000390.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053997885.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054005067.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053997783.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054000689.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054010687.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_054000770.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286	"Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation"
XP_054001653.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_054006202.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054010923.1	12	MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-7230;MetaCyc: PWY-5857;MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5873;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7233	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)"
XP_054002465.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054012534.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053995365.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_054001873.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054005939.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054001395.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005568.1	7	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.22	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism"
XP_053999174.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054010974.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054008305.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-6784531;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"tRNA processing in the nucleus";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins"
XP_054015676.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_054006847.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054004567.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_054016849.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054014459.1	13	Reactome: R-HSA-2214320;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-1474244;Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-216083;Reactome: R-HSA-186797	"Anchoring fibril formation";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Collagen degradation";"Extracellular matrix organization";"Crosslinking of collagen fibrils";"NCAM1 interactions";"Integrin cell surface interactions";"Signaling by PDGF"
XP_054003453.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_054004068.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053998249.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054006584.1	6	MetaCyc: PWY-7442;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606	"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation II"
XP_054008471.1	5	KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053997900.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053996230.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_053999159.1	3	MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_054005900.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_054010959.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054001737.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053998149.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054009594.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440	"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network"
XP_054015690.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_054009252.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053997820.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053999828.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054015389.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)"
XP_054005387.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054015704.1	5	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-8948751	"Ub-specific processing proteases";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity"
XP_054000884.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053996223.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054010909.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054009432.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_054006527.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_054006028.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054010697.1	18	Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-6807505	"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA polymerase II transcribes snRNA genes"
XP_054015625.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_054003891.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952	"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions"
XP_054000699.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053996450.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_054005373.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054005324.1	7	Reactome: R-HSA-1855204;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36	"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism"
XP_054005793.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_054013206.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152	"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_054000380.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472	"Formation of the beta-catenin:TCF transactivating complex";"Neddylation";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054003731.1	12	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells"
XP_054015754.1	10	Reactome: R-HSA-5684264;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590	"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling"
XP_054001979.1	17	KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-1622;MetaCyc: PWY-7115;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-6728	"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle"
XP_054009536.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053998468.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_053999047.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053997291.1	3	KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286	"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation"
XP_053998558.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes"
XP_054004407.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054005291.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054014011.1	5	MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-6798695;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate"
XP_054003233.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053996721.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-390471	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054004237.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946	"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin"
XP_054003403.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054004778.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_054004398.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054003133.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054010481.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054011362.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_054005397.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_054010853.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011935.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053998619.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054000325.1	11	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"activated TAK1 mediates p38 MAPK activation";"p38MAPK events";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054005238.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054011993.1	4	Reactome: R-HSA-1362409;Reactome: R-HSA-947581;MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7	"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism"
XP_053997238.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054000734.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_054012492.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053997777.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054006594.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054007095.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054016553.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_054006252.1	13	KEGG: 05170+2.7.11.1;Reactome: R-HSA-5627117;Reactome: R-HSA-3928663;Reactome: R-HSA-3928662;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097	"Human immunodeficiency virus 1 infection";"RHO GTPases Activate ROCKs";"EPHA-mediated growth cone collapse";"EPHB-mediated forward signaling";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway"
XP_054010022.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053996259.1	13	Reactome: R-HSA-2424491;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-2029485;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-9027277;Reactome: R-HSA-1855204;Reactome: R-HSA-202433;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11	"DAP12 signaling";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Role of phospholipids in phagocytosis";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Synthesis of IP3 and IP4 in the cytosol";"Generation of second messenger molecules";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054001065.1	14	MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7602	"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_054005138.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_054001887.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_053999130.1	30	Reactome: R-HSA-111447;Reactome: R-HSA-389513;Reactome: R-HSA-211163;Reactome: R-HSA-8876198;Reactome: R-HSA-8941332;Reactome: R-HSA-389357;Reactome: R-HSA-198693;Reactome: R-HSA-69656;Reactome: R-HSA-1257604;Reactome: R-HSA-199418;KEGG: 04150+2.7.11.1;Reactome: R-HSA-69202;Reactome: R-HSA-5218920;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9614399;Reactome: R-HSA-198323;Reactome: R-HSA-6804757;Reactome: R-HSA-9634638;Reactome: R-HSA-6804758;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804759;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-392451;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-5628897	"Activation of BAD and translocation to mitochondria";"CTLA4 inhibitory signaling";"AKT-mediated inactivation of FOXO1A";"RAB GEFs exchange GTP for GDP on RABs";"RUNX2 regulates genes involved in cell migration";"CD28 dependent PI3K/Akt signaling";"AKT phosphorylates targets in the nucleus";"Cyclin A:Cdk2-associated events at S phase entry";"PIP3 activates AKT signaling";"Negative regulation of the PI3K/AKT network";"mTOR signaling pathway";"Cyclin E associated events during G1/S transition";"VEGFR2 mediated vascular permeability";"Human immunodeficiency virus 1 infection";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the cytosol";"Regulation of TP53 Degradation";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Regulation of TP53 Activity through Acetylation";"Thermogenesis";"Regulation of TP53 Activity through Association with Co-factors";"Relaxin signaling pathway";"Human papillomavirus infection";"Downregulation of ERBB2:ERBB3 signaling";"G beta:gamma signalling through PI3Kgamma";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Regulation of PTEN stability and activity";"TP53 Regulates Metabolic Genes"
XP_054004331.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054011356.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes"
XP_054001726.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_054014200.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054006166.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054012596.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054003378.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_054001544.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_054012343.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053995571.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054014100.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs"
XP_053997712.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054008003.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054005026.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053998959.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216	"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization"
XP_054011315.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism"
XP_053997026.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching"
XP_054009456.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054001614.1	3	KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639	"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis"
XP_054008665.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476	"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events"
XP_053998438.1	5	KEGG: 00230+2.7.4.3;KEGG: 00230+2.7.4.10;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219	"Purine metabolism";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis"
XP_054008952.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_054003163.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053998208.1	2	MetaCyc: PWY-7802;MetaCyc: PWY-7799	"N-end rule pathway II (prokaryotic)";"Arg/N-end rule pathway (eukaryotic)"
XP_054003520.1	26	Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276	"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Recycling pathway of L1";"Gap junction assembly";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_054010310.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054010149.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054009462.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054006184.1	8	KEGG: 04658+3.1.3.16;KEGG: 00564+3.1.3.27;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5668	"Th1 and Th2 cell differentiation";"Glycerophospholipid metabolism";"T cell receptor signaling pathway";"Cardiolipin biosynthesis II";"Synthesis of PG";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis I"
XP_054007383.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054008966.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_054011079.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053995383.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_054009552.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054003344.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054016808.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054001578.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_054005765.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-114604	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Interleukin-7 signaling";"RET signaling";"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"GPVI-mediated activation cascade"
XP_054010007.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053997863.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400	"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Translesion synthesis by REV1";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER"
XP_054013645.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054011666.1	12	MetaCyc: PWY-6807;KEGG: 00511+3.2.1.25;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-8853383;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292	"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Lysosomal oligosaccharide catabolism";"HS-GAG degradation";"Galactose metabolism";"Neutrophil degranulation";"Sphingolipid metabolism";"MPS VII - Sly syndrome"
XP_054007826.1	4	KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_053997610.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053996248.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054006136.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054005610.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053998974.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_054014460.1	13	Reactome: R-HSA-2243919;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-3000178	"Crosslinking of collagen fibrils";"NCAM1 interactions";"Signaling by PDGF";"Integrin cell surface interactions";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Laminin interactions";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Collagen degradation";"ECM proteoglycans"
XP_054003868.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_053998923.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism"
XP_054011445.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054014940.1	9	Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167172	"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome"
XP_054002255.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053998491.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054003414.1	19	Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066	"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_054011965.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053997168.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054001035.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_054007063.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053999574.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054009227.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054010960.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054004361.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053999160.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_054016433.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_054016103.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_054008710.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054007605.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054015111.1	13	KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-5913	"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)"
XP_054007546.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500	"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle"
XP_054000023.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054011602.1	3	Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471	"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response"
XP_054005037.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053996469.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054007724.1	10	Reactome: R-HSA-917729;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-6807004	"Endosomal Sorting Complex Required For Transport (ESCRT)";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"Negative regulation of MET activity"
XP_054007393.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_054002105.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_053995393.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054015211.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-9029569;Reactome: R-HSA-5625886;Reactome: R-HSA-983231;Reactome: R-HSA-3214815;Reactome: R-HSA-3214842;Reactome: R-HSA-9018519	"Regulation of PTEN gene transcription";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Factors involved in megakaryocyte development and platelet production";"HDACs deacetylate histones";"HDMs demethylate histones";"Estrogen-dependent gene expression"
XP_053997538.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054004091.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958	"Cargo recognition for clathrin-mediated endocytosis";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)"
XP_054016420.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054007773.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054013215.1	52	Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-5601884;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-73980;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-5250924;Reactome: R-HSA-203927;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-72203;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167160	"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"B-WICH complex positively regulates rRNA expression";"MicroRNA (miRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection"
XP_054007875.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054006456.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_054002921.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053997449.1	7	KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1	"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection"
XP_054000617.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054007442.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054001244.1	8	Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9620244	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation"
XP_054010619.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858	"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity"
XP_054006566.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054012196.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053998930.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054002801.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053998022.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C"
XP_054008029.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054000866.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054007171.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053995837.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054006127.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053996260.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054001767.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_054007797.1	7	MetaCyc: PWY-6277;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;Reactome: R-HSA-73817;MetaCyc: PWY-7282;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism"
XP_053997075.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053998481.1	33	Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025	"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation"
XP_054003840.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_054006227.1	5	Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948	"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"RAF activation";"Signaling downstream of RAS mutants"
XP_054010057.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054003071.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_054013132.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053998909.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053997240.1	6	Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_054004537.1	26	Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-5626467;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-437239	"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Separation of Sister Chromatids";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"Gap junction assembly";"Recycling pathway of L1"
XP_053997591.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053998258.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053998829.1	4	MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7286	"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_054001913.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_054009236.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_054005140.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054003595.1	4	KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;Reactome: R-HSA-72731;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_054006254.1	13	KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1	"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection"
XP_053996311.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_054010073.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054006592.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054007970.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054002788.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_054007695.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054011364.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054004640.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6906;MetaCyc: PWY-6855;Reactome: R-HSA-70171	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Glycolysis"
XP_054006154.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_054012494.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054001665.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_054010622.1	16	Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-192823	"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation"
XP_054008614.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_053995633.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054016135.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054011243.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_054012971.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_054008578.1	9	Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736	"Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors"
XP_054011036.1	5	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-189085	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate"
XP_053998893.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_054001542.1	4	Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22	"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism"
XP_053998835.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053997714.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_053995996.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_054014525.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_054011143.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054016791.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054016371.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054015910.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_054016831.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054008077.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054007329.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054002429.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-69231	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Cyclin D associated events in G1"
XP_054016177.1	5	Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_054008819.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054006279.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110320;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching";"Translesion synthesis by REV1";"Translesion Synthesis by POLH";"Dual incision in TC-NER"
XP_054006628.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)"
XP_054001316.1	4	MetaCyc: PWY-6129;Reactome: R-HSA-4755609;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87	"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis"
XP_053996441.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054011682.1	7	KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054009434.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_054002881.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054015766.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054014611.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_054005461.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054003555.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2	"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway"
XP_054003465.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053998298.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_054011848.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_054005551.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5693565;Reactome: R-HSA-8940973;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-428890;Reactome: R-HSA-69231	"T cell receptor signaling pathway";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX2 regulates osteoblast differentiation";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"Cyclin D associated events in G1"
XP_054015076.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054016781.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054007986.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_054008363.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053998607.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054006486.1	13	Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-422356	"Effects of PIP2 hydrolysis";"PLC beta mediated events";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion"
XP_054004668.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444	"Mitotic Prometaphase";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_054009592.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_054014347.1	22	MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-5353;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-6958;MetaCyc: PWY-7049;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7053	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis I (lower eukaryotes)"
XP_054016183.1	17	Reactome: R-HSA-8951664;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-174084	"Neddylation";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_053995685.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_054000369.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053996589.1	7	KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539	"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism"
XP_054010367.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385	"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_054009154.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054002798.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-445095	"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins"
XP_054007478.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition"
XP_054002838.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_054006582.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054012106.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_053998720.1	14	KEGG: 00565+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"Ether lipid metabolism";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_054016642.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053996647.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054010161.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex"
XP_054014472.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054012206.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054016044.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054008767.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220	"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Mitotic Prometaphase";"HCMV Early Events";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins"
XP_054008083.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054010261.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_054015348.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054002891.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054010917.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053995934.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054012532.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054014576.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054002046.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_054009179.1	2	Reactome: R-HSA-83936;Reactome: R-HSA-2564830	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Cytosolic iron-sulfur cluster assembly"
XP_054006204.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054011692.1	5	Reactome: R-HSA-5675221;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409	"Negative regulation of MAPK pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation"
XP_054002233.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054010972.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053999172.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_054010865.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998561.1	8	Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210	"Ub-specific processing proteases";"Dual incision in TC-NER";"Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_054002295.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054010763.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_054001822.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_054009628.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054001053.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_054006104.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_054011860.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053998326.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054014845.1	10	Reactome: R-HSA-1912408;Reactome: R-HSA-2197563;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947	"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053999272.1	5	Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-3108214	"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"SUMOylation of DNA damage response and repair proteins"
XP_054002403.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054010918.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_054011166.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_054005349.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053997110.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053998187.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054001943.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008768.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054011266.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862	"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_054007801.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-7282	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_053996648.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054008583.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054002956.1	5	MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109	"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis"
XP_054006362.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_054009899.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053996369.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054009739.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054006993.1	10	KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041	"Glutathione metabolism";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle"
XP_054009627.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054012800.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011252.1	10	KEGG: 04070+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6554;MetaCyc: PWY-6361	"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_054004501.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054002875.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053999660.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054002335.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054006750.1	17	Reactome: R-HSA-167287;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-75955;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA Polymerase II Transcription Elongation";"T cell receptor signaling pathway";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_054001463.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi"
XP_054015576.1	24	Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-9619483;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148	"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Activation of AMPK downstream of NMDARs";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_054006912.1	4	MetaCyc: PWY-7919;KEGG: 00510+3.2.1.113;KEGG: 00513+3.2.1.113;Reactome: R-HSA-901032	"Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"ER Quality Control Compartment (ERQC)"
XP_054013302.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053998608.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054007412.1	14	MetaCyc: PWY-7411;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-6453;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587	"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Stigma estolide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)"
XP_054004816.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054013070.1	3	Reactome: R-HSA-191859;Reactome: R-HSA-3214858;Reactome: R-HSA-6804760	"snRNP Assembly";"RMTs methylate histone arginines";"Regulation of TP53 Activity through Methylation"
XP_054016385.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054002797.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054012799.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054015472.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_054001529.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis"
XP_054011028.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_054014348.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054007516.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054008740.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053996732.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_054011584.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_054004714.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-3301854;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-170822	"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"ISG15 antiviral mechanism";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_054009993.1	6	Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13	"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system"
XP_054006627.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
XP_054010098.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434	"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Gap junction assembly";"Recycling pathway of L1";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Kinesins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054002383.1	11	Reactome: R-HSA-512988;Reactome: R-HSA-389948;Reactome: R-HSA-432142;Reactome: R-HSA-114604;Reactome: R-HSA-210990;Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-388841;Reactome: R-HSA-877312;Reactome: R-HSA-9008059;Reactome: R-HSA-391160	"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PD-1 signaling";"Platelet sensitization by LDL";"GPVI-mediated activation cascade";"PECAM1 interactions";"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"Costimulation by the CD28 family";"Regulation of IFNG signaling";"Interleukin-37 signaling";"Signal regulatory protein family interactions"
XP_054015525.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054016178.1	5	Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118	"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"DNA methylation"
XP_054012428.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-9614657	"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes"
XP_054000311.1	4	MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Entner-Doudoroff pathway I";"Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053995758.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_054009889.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054009636.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_054003964.1	4	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_054011847.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_054008535.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_053998297.1	3	Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311	"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance"
XP_054013632.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288	"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1"
XP_054013352.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_054003722.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol"
XP_053998197.1	3	MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783	"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_053997640.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_054003055.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Ca2+ pathway";"Deactivation of the beta-catenin transactivating complex"
XP_054009421.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054013034.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054007255.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053995255.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054011102.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054000441.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_053998391.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054002787.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_054004461.1	12	Reactome: R-HSA-5620912;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497	"Anchoring of the basal body to the plasma membrane";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054016775.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_054016824.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_054010746.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054004551.1	14	Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-380284;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-380259	"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Loss of proteins required for interphase microtubule organization from the centrosome";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Loss of Nlp from mitotic centrosomes"
XP_053998173.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054008078.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054011536.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_054010340.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_053999919.1	16	Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Ca2+ pathway";"Estrogen-dependent gene expression"
XP_054014752.1	13	MetaCyc: PWY-6807;Reactome: R-HSA-4341670;Reactome: R-HSA-2206308;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662	"Xyloglucan degradation II (exoglucanase)";"Defective NEU1 causes sialidosis";"MPS IV - Morquio syndrome B";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"HS-GAG degradation";"Galactose metabolism";"Sialic acid metabolism";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism"
XP_053996813.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_053998124.1	5	KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;Reactome: R-HSA-532668	"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054001644.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_054007851.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054000961.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054008577.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-438066	"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_054013006.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_054012709.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054010058.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054006679.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_054006228.1	5	Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948	"RAF activation";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants"
XP_054016677.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054016857.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054007798.1	7	MetaCyc: PWY-6277;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II"
XP_053997575.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054000469.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054010467.1	34	Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-9639288;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-170822;Reactome: R-HSA-68877	"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Amino acids regulate mTORC1";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase"
XP_054000559.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_054001768.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_054010557.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053995378.1	4	KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221	"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis"
XP_054009830.1	31	MetaCyc: PWY-5147;MetaCyc: PWY-5994;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5989;MetaCyc: PWY-5973;MetaCyc: PWY-7723;Reactome: R-HSA-75105;MetaCyc: PWY-6799;MetaCyc: PWY-6113;MetaCyc: PWY-5966-1;MetaCyc: PWY-8049;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5366;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-5367;MetaCyc: PWY-8012;Reactome: R-HSA-9029558;MetaCyc: PWY-6519;MetaCyc: PWY-5971;Reactome: R-HSA-199220;MetaCyc: PWY-7858;MetaCyc: PWY-6282;MetaCyc: PWYG-321;MetaCyc: PWY-7746;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-7664;MetaCyc: PWY-7663	"Oleate biosynthesis I (plants)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Stearate biosynthesis II (bacteria and plants)";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Fatty acyl-CoA biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis II (plants and bacteria)";"Biotin metabolism";"Bryostatin biosynthesis";"Petroselinate biosynthesis";"Mupirocin biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"8-amino-7-oxononanoate biosynthesis I";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"";"Mycobacterial sulfolipid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Oleate biosynthesis IV (anaerobic)";"Gondoate biosynthesis (anaerobic)"
XP_054003571.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167238	"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Neddylation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation"
XP_054006128.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054003146.1	13	KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;MetaCyc: PWY-7184;KEGG: 00770+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-6545;MetaCyc: PWY-7187	"Pyrimidine metabolism";"Purine metabolism";"Starch and sucrose metabolism";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pantothenate and CoA biosynthesis";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_054015318.1	5	KEGG: 00564+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_054009776.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053999147.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_054016014.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054014039.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_054013772.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053998257.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053997091.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053996617.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054003033.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_054009543.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_054016612.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054001265.1	10	Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-9609736	"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors"
XP_054008214.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053998351.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054013313.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053997537.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054000160.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_054012730.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054008114.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_054006725.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054012890.1	12	Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1	"DCC mediated attractive signaling";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Thermogenesis";"G alpha (12/13) signalling events";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (q) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"NRAGE signals death through JNK";"Human cytomegalovirus infection"
XP_053999764.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053998426.1	2	KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_054011504.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053995403.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884	"Wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I"
XP_054006874.1	5	Reactome: R-HSA-5687128;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16	"MAPK6/MAPK4 signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway"
XP_054014792.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_054014832.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_054012545.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_054000618.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054008529.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_054007891.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054003867.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_054011944.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_054003085.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054012606.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones"
XP_053997081.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_054002996.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5626467	"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"RHO GTPases activate IQGAPs"
XP_053996247.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054014641.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359	"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Purine metabolism";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation"
XP_054003616.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054004863.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054004765.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012121.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054016242.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054002970.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_054004026.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053996411.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053995220.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054000530.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054007788.1	3	Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_054001346.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_054009228.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054009780.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053995788.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053997167.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054012774.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054007563.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-210500	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle"
XP_053999074.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_054003915.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_054001535.1	6	MetaCyc: PWY-6733;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054002695.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_054007120.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_054005911.1	6	MetaCyc: PWY-6317;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527	"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation"
XP_053995453.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-5080;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041	"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_054015269.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053998842.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_054012394.1	9	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation"
XP_054006830.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054005267.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054002633.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053997911.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_054012825.1	8	MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27	"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"Propanoate metabolism"
XP_054008503.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054005526.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_054004268.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_054013062.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_053997526.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_054005361.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053997744.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054004168.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054003020.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054003365.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054003932.1	26	Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Gap junction assembly";"Recycling pathway of L1";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054014782.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-2162123;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_054012880.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-164378	"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"PKA activation in glucagon signalling"
XP_053999059.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053995185.1	6	KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_053995429.1	7	MetaCyc: PWY-5265;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;Reactome: R-HSA-446193;MetaCyc: PWY-6471;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13	"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis"
XP_054013056.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340	"PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation"
XP_054008644.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_054001577.1	3	Reactome: R-HSA-1483213;MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65	"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism"
XP_054016807.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_054004581.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_054011711.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_054009823.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_054007285.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-180746;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159236	"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear import of Rev protein";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"snRNP Assembly";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_054009654.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054009874.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane"
XP_053998936.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-212436;Reactome: R-HSA-1368082	"Estrogen-dependent gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Generic Transcription Pathway";"RORA activates gene expression"
XP_054016522.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012	"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053999102.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_054010053.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053999202.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-1362277;Reactome: R-HSA-176187	"Activation of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Transcription of E2F targets under negative control by DREAM complex";"Activation of ATR in response to replication stress"
XP_053996028.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_054001972.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054006123.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054007735.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054008948.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_054001763.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_054004071.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_054012541.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_054012190.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053995793.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054006560.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054004840.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053995895.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054002424.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053999536.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_054013539.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053998355.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054013968.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054009047.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054008558.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054015313.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053995291.1	8	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_054007540.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054006721.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053995540.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054008057.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054004595.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054001161.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054014232.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054007397.1	20	Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5685938;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121	"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Polymerase switching";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI"
XP_054002497.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054015772.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054013318.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_054005146.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053995238.1	5	Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409	"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis"
XP_054015392.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_054000528.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053998612.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054011369.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053997146.1	3	MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33	"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis"
XP_054006159.1	4	MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3	"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism"
XP_054006908.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053997095.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053996594.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054000027.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054016698.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757	"HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation"
XP_054005095.1	42	Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-1221632;Reactome: R-HSA-171306;Reactome: R-HSA-5250924;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-3214815;Reactome: R-HSA-606279;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-2559586;Reactome: R-HSA-1912408;Reactome: R-HSA-2559582;Reactome: R-HSA-110328;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-912446;Reactome: R-HSA-5578749;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-427359	"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"Meiotic synapsis";"Packaging Of Telomere Ends";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"HDACs deacetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"DNA Damage/Telomere Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"Meiotic recombination";"Transcriptional regulation by small RNAs";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"HCMV Late Events";"DNA methylation";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"SIRT1 negatively regulates rRNA expression"
XP_054002308.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_054010029.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_053997033.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054003091.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053999847.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053998984.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-2781;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"Zeatin biosynthesis";"tRNA modification in the mitochondrion"
XP_053996266.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_054005571.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053997719.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053998857.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054000613.1	17	Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-69183;Reactome: R-HSA-174417;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-174414;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397	"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the lagging strand";"Telomere C-strand (Lagging Strand) Synthesis";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the C-strand of the telomere";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_054003575.1	16	Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-1234176;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-167200	"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Neddylation";"Vif-mediated degradation of APOBEC3G";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_054003422.1	19	Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9022692	"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF activation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity"
XP_054000848.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_054000914.1	9	MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664	"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_054006047.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-216083;Reactome: R-HSA-3000178	"Molecules associated with elastic fibres";"Syndecan interactions";"Integrin cell surface interactions";"ECM proteoglycans"
XP_054016049.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054011715.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054007281.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054004868.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054010710.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_054006548.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_054013550.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_054007067.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation"
XP_053995885.1	8	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition"
XP_054012180.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054007783.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054001097.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_054010316.1	57	Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-5689603	"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"UCH proteinases"
XP_053996432.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054016107.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9636467	"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Blockage of phagosome acidification"
XP_054011099.1	3	KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1	"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism"
XP_053997932.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_054005365.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054001598.1	5	Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.20	"Metabolism of folate and pterines";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate"
XP_054007939.1	12	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-194840	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Signaling by FGFR1 in disease";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"Rho GTPase cycle"
XP_054016207.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054009174.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054006209.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054003361.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054003167.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_054013169.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5466	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis"
XP_053996415.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054014452.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054008716.1	3	Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence"
XP_054003911.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination"
XP_053999266.1	4	Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118	"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation"
XP_054001531.1	6	MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884	"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I"
XP_054004520.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_054011218.1	3	Reactome: R-HSA-9603798;Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_054016301.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054013269.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_054004163.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054014466.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_054010952.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054011732.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053997085.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054000364.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053998471.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054006230.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053997867.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_054014556.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_054010003.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054015382.1	2	KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386	"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_054001024.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_054008310.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_054014645.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418594	"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (i) signalling events"
XP_054012489.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054007820.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054012125.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053998142.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053995820.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_054006130.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_054008763.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295	"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation"
XP_054001948.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054016381.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5685938	"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"HDR through Single Strand Annealing (SSA)"
XP_054013241.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157	"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions"
XP_054015096.1	4	MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175	"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism"
XP_054008972.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953	"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation"
XP_053998979.1	7	Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12;Reactome: R-HSA-5362517;KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+2.3.1.12	"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)"
XP_054015245.1	17	MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;KEGG: 00230+2.4.2.1;KEGG: 00760+2.4.2.1;Reactome: R-HSA-74217;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-6609;MetaCyc: PWY-5532;MetaCyc: PWY-6611;MetaCyc: PWY-4202;MetaCyc: PWY-6644	"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Purine salvage";"Pyrimidine metabolism";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine catabolism";"Adenine and adenosine salvage III";"Nucleoside and nucleotide degradation (archaea)";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis"
XP_054009018.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054010913.1	12	MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_053998385.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_054008588.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054013590.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_054001057.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)"
XP_054006480.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-1489509;Reactome: R-HSA-381676	"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_054015302.1	10	KEGG: 00051+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054002407.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054012409.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_054003001.1	16	Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409	"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_053997663.1	56	Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858	"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity"
XP_054003419.1	19	Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-877300;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955	"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Interferon gamma signaling";"Ion transport by P-type ATPases";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"RAF activation";"HSF1-dependent transactivation";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_054001468.1	4	MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_054008261.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054015841.1	3	KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_054009988.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163	"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway"
XP_054016608.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_054007980.1	14	KEGG: 00190+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-6728;MetaCyc: PWY-4302;Reactome: R-HSA-611105;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-3781	"Oxidative phosphorylation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Respiratory electron transport";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)"
XP_053997005.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054010767.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-8854518	"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2"
XP_054001558.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_054005810.1	5	Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER"
XP_053995201.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_053995626.1	7	KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3	"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism"
XP_053997810.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054007626.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_054011866.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053998320.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_054003668.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion"
XP_054016061.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053998954.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing"
XP_054008367.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054012200.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054007925.1	14	MetaCyc: PWY-6728;MetaCyc: PWY-561;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;MetaCyc: PWY-3781	"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)"
XP_053996282.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053998544.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054003110.1	5	Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_054016287.1	6	Reactome: R-HSA-5632987;Reactome: R-HSA-6796648;Reactome: R-HSA-5545483;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5358606	"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"
XP_054013347.1	7	KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-4702	"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Phytate degradation I"
XP_053998726.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054012430.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054011023.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054016187.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-6901;MetaCyc: PWY-7383;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-5723	"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Rubisco shunt"
XP_053999292.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054007488.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_054009998.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_054000054.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_054006572.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84	"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_054001960.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314	"Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053996711.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053995753.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053995855.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_054016173.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053995675.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054012423.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_054000965.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_054011341.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_054008598.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053998873.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_054007251.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_054013611.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_054004646.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054005314.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_053998333.1	2	Reactome: R-HSA-69273;Reactome: R-HSA-8862803	"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_054006018.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054006476.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-2029485;Reactome: R-HSA-5578775;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-1489509;Reactome: R-HSA-5607763;Reactome: R-HSA-422356	"PLC beta mediated events";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Role of phospholipids in phagocytosis";"Ion homeostasis";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DAG and IP3 signaling";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion"
XP_053998395.1	4	KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2	"Selenocompound metabolism";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_054016771.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_054002226.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)"
XP_054015086.1	29	Reactome: R-HSA-6796648;Reactome: R-HSA-6803204;Reactome: R-HSA-5693579;Reactome: R-HSA-349425;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803207;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804757;Reactome: R-HSA-6804760;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-3371453;KEGG: 04151+2.7.11.1;Reactome: R-HSA-69541;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568	"TP53 Regulates Transcription of DNA Repair Genes";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Homologous DNA Pairing and Strand Exchange";"Autodegradation of the E3 ubiquitin ligase COP1";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Degradation";"Regulation of TP53 Activity through Methylation";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"HDR through Homologous Recombination (HRR)";"Regulation of HSF1-mediated heat shock response";"PI3K-Akt signaling pathway";"Stabilization of p53";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054001440.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054008097.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_054004555.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253	"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex"
XP_054011009.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604	"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053997722.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_054008531.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_054006199.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_054002567.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054005964.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-380994	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_054000079.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-6798695;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neutrophil degranulation";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway"
XP_054010982.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054010077.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053996464.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054015034.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_054009425.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_054001508.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_054015760.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-9609736;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-380320;Reactome: R-HSA-8955332;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434	"Cilium Assembly";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Assembly and cell surface presentation of NMDA receptors";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"MHC class II antigen presentation";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"Kinesins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Carboxyterminal post-translational modifications of tubulin";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053996554.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054003640.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054014586.1	2	Reactome: R-HSA-73621;Reactome: R-HSA-500753	"Pyrimidine catabolism";"Pyrimidine biosynthesis"
XP_054001149.1	3	KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596	"Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I"
XP_054011147.1	11	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-193692	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulated proteolysis of p75NTR"
XP_053998178.1	20	Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-389357;Reactome: R-HSA-9639288;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-165159	"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Thermogenesis";"Regulation of PTEN gene transcription";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"Human papillomavirus infection";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"VEGFR2 mediated vascular permeability";"mTOR signalling"
XP_054008073.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-937072;Reactome: R-HSA-936964	"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_054001249.1	8	KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324	"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_054015521.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_054008622.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053998278.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053998629.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_053997646.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054002783.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054002885.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054016657.1	7	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-606279;Reactome: R-HSA-5689880;Reactome: R-HSA-201722;Reactome: R-HSA-171319;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases";"Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase";"UCH proteinases"
XP_054005646.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054012069.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053999769.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_054016298.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053996965.1	5	Reactome: R-HSA-211945;Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211976	"Phase I - Functionalization of compounds";"PPARA activates gene expression";"Xenobiotics";"Aryl hydrocarbon receptor signalling";"Endogenous sterols"
XP_054010078.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054014615.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053995638.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054005465.1	8	Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex"
XP_054002458.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_053997465.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054008219.1	5	Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_054000213.1	7	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054002181.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053998738.1	14	KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7417;MetaCyc: PWY-6803;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-8051	"Ether lipid metabolism";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Anandamide biosynthesis I"
XP_053997945.1	29	Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-5696400;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-113418;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-112382;Reactome: R-HSA-73762	"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation"
XP_053998277.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_054014916.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054011248.1	10	MetaCyc: PWY-6362;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6554;MetaCyc: PWY-6361	"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_054008573.1	9	Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-442982	"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_054008746.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054015021.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_054000113.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053996445.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054000292.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054010535.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053998831.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053996079.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_054000464.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054000192.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054008410.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_054006854.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053995487.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_054012704.1	7	MetaCyc: PWY-5514;MetaCyc: PWY-8004;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336;MetaCyc: PWY-6906	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Chitin derivatives degradation"
XP_054006623.1	5	Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994	"PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_054009997.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054014632.1	3	MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368	"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_053998193.1	8	Reactome: R-HSA-73614;MetaCyc: PWY-6556;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;MetaCyc: PWY-7181;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5;KEGG: 00983+3.5.4.5	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_054012676.1	3	Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141	"Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_054004964.1	3	Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691	"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054016231.1	9	Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955	"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_054010740.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271	"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus"
XP_054006017.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_054007691.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_054016401.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053998293.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191	"Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC"
XP_054011843.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_054004055.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054000944.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_054008368.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_054007742.1	7	MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753	"UMP biosynthesis II";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis"
XP_053998455.1	7	KEGG: 00280+4.1.3.4;KEGG: 00281+4.1.3.4;Reactome: R-HSA-77111;KEGG: 00650+4.1.3.4;Reactome: R-HSA-9033241;MetaCyc: PWY-5074;KEGG: 00072+4.1.3.4	"Valine, leucine and isoleucine degradation";"Geraniol degradation";"Synthesis of Ketone Bodies";"Butanoate metabolism";"Peroxisomal protein import";"Mevalonate degradation";"Synthesis and degradation of ketone bodies"
XP_054014302.1	10	MetaCyc: PWY-6527;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-6317;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-6397	"Stachyose degradation";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis"
XP_054003667.1	24	Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-1445148;Reactome: R-HSA-6807878;Reactome: R-HSA-9609736;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-380320;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-mediated anterograde transport";"Assembly and cell surface presentation of NMDA receptors";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Gap junction assembly";"Recycling pathway of L1";"MHC class II antigen presentation";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Kinesins";"Recruitment of NuMA to mitotic centrosomes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054002291.1	10	Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+2.7.2.3;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-6901;MetaCyc: PWY-6886	"Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)"
XP_053998565.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_054013669.1	11	KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-3881;MetaCyc: PWY-7456;MetaCyc: PWY-3861;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-7586;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205	"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Beta-(1,4)-mannan degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose"
XP_054010861.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054012926.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054016561.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054002191.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054014841.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054016188.1	15	MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.40	"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis"
XP_054000504.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054006762.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053999965.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054010165.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_054002833.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-6783310;Reactome: R-HSA-983168	"Protein ubiquitination";"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054006350.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_054002373.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_054011160.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054007473.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_054002793.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_054008587.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054015596.1	5	Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04660+3.1.3.16	"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"T cell receptor signaling pathway"
XP_053995510.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-196757;KEGG: 00670+1.5.1.3;KEGG: 00790+1.5.1.3;MetaCyc: PWY-3841;Reactome: R-HSA-1474151;MetaCyc: PWY-6614	"G1/S-Specific Transcription";"Metabolism of folate and pterines";"One carbon pool by folate";"Folate biosynthesis";"Folate transformations II (plants)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis"
XP_054009017.1	8	Reactome: R-HSA-975957;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054008088.1	3	KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662	"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism"
XP_054013090.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_054001947.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053995497.1	56	Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-4608870;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5632684;Reactome: R-HSA-2871837;Reactome: R-HSA-75815	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Asymmetric localization of PCP proteins";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RAS by GAPs";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog 'on' state";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D"
XP_054004810.1	12	Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1169408;Reactome: R-HSA-72662;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"ISG15 antiviral mechanism";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054015264.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111469;Reactome: R-HSA-111457;Reactome: R-HSA-111463	"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response";"Release of apoptotic factors from the mitochondria";"SMAC (DIABLO) binds to IAPs"
XP_054009987.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_054006609.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_054012779.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053999079.1	3	Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880	"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases"
XP_054001467.1	13	KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662	"Various types of N-glycan biosynthesis";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism"
XP_054016785.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_054012511.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054012680.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_054007308.1	7	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Thermogenesis"
XP_054015164.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054015570.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_054005505.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054001058.1	14	MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7725;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7619	"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis"
XP_054009623.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053998433.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_054002251.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053997414.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_054014062.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_054010644.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053998495.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_054011961.1	7	KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61	"Citrate cycle (TCA cycle)";"Lysine catabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation"
XP_054002976.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053995226.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054001119.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054003168.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism"
XP_054003610.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053999692.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054000202.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_054014056.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054009907.1	2	Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100	"Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis"
XP_053999094.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053997868.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_054001573.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_054011441.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_054006547.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054016549.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_054004867.1	3	Reactome: R-HSA-2173791;Reactome: R-HSA-420029;Reactome: R-HSA-4608870	"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Tight junction interactions";"Asymmetric localization of PCP proteins"
XP_054003863.1	5	MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism"
XP_054012886.1	12	Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1	"DCC mediated attractive signaling";"Rho GTPase cycle";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human papillomavirus infection";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human cytomegalovirus infection";"G alpha (q) signalling events";"mTOR signaling pathway";"PI3K-Akt signaling pathway"
XP_053997344.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648	"G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK"
XP_054005761.1	16	Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-8853659;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-1433557;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-512988	"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"RET signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"Signaling by SCF-KIT";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling"
XP_054013641.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054000847.1	3	Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841	"Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines"
XP_054004616.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053997761.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054006884.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053995457.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation"
XP_054001597.1	5	KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757	"One carbon pool by folate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)";"Metabolism of folate and pterines"
XP_054011599.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053999528.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471	"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"LDL clearance";"LDL remodeling";"Chylomicron assembly";"Retinoid metabolism and transport";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Chylomicron remodeling";"VLDL assembly";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors"
XP_053996364.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054001098.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053997520.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins"
XP_054016108.1	8	Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-1222556	"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"ROS and RNS production in phagocytes"
XP_053997163.1	15	Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939	"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)"
XP_054007068.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054016829.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664	"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation"
XP_054015402.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_054006827.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_054007137.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_054012784.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_053999084.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_054002307.1	3	Reactome: R-HSA-5617472;Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_054007407.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054016697.1	3	Reactome: R-HSA-6804757;Reactome: R-HSA-9609690;Reactome: R-HSA-3899300	"Regulation of TP53 Degradation";"HCMV Early Events";"SUMOylation of transcription cofactors"
XP_054014313.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054015132.1	4	KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III";"Arginine and proline metabolism"
XP_054007778.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_054009689.1	15	Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333	"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated"
XP_054013317.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053995237.1	4	Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312	"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1"
XP_054005595.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054001368.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_054002980.1	17	Reactome: R-HSA-5685942;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5685939;Reactome: R-HSA-3270619;Reactome: R-HSA-5693616	"HDR through Homologous Recombination (HRR)";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through MMEJ (alt-NHEJ)";"IRF3-mediated induction of type I IFN";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053997533.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054002498.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053998229.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054009796.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5675221;Reactome: R-HSA-2500257;Reactome: R-HSA-432142;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-68877;Reactome: R-HSA-5358749;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-389513;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337	"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Negative regulation of MAPK pathway";"Resolution of Sister Chromatid Cohesion";"Platelet sensitization by LDL";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Mitotic Prometaphase";"S37 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"CTLA4 inhibitory signaling";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding"
XP_053998858.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054009376.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_054010214.1	3	KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism"
XP_054008222.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053997071.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053998485.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054005071.1	5	Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413	"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression"
XP_054008122.1	16	Reactome: R-HSA-166058;Reactome: R-HSA-1257604;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-209543;Reactome: R-HSA-3134963;Reactome: R-HSA-975110;Reactome: R-HSA-1236974;Reactome: R-HSA-975155;Reactome: R-HSA-6811558;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-5602498;Reactome: R-HSA-5603037;Reactome: R-HSA-1810476;Reactome: R-HSA-5603041	"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"p75NTR recruits signalling complexes";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER-Phagosome pathway";"MyD88 dependent cascade initiated on endosome";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 deficiency (TLR2/4)";"IRAK4 deficiency (TLR5)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR2/4)"
XP_053999914.1	7	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608;Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-140837	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation";"G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation"
XP_054016022.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_054003449.1	7	Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-72662	"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_054013447.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054000252.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053996027.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_054014443.1	5	KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084	"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_054011589.1	13	Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-380972;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"mTOR signalling";"HSF1-dependent transactivation";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_054006734.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-168333;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-9634638	"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_054002703.1	8	KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1	"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_054004571.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054012041.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_054002805.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_054016673.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_054006060.1	16	Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176412	"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C"
XP_054012870.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_054016755.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214	"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_054016853.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053999036.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_054014963.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_054014772.1	12	MetaCyc: PWY-6932;Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4	"Selenate reduction";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Purine metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Purine metabolism";"Sulfur metabolism";"Selenocompound metabolism";"Monobactam biosynthesis"
XP_054013111.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_054012896.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_054008058.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_054014392.1	4	KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193	"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I"
XP_054004095.1	12	Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1861	"Gluconeogenesis";"Methane metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_054008557.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054002101.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_054007331.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053995871.1	3	Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681	"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling"
XP_054001918.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054002431.1	7	Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-69231	"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"Cyclin D associated events in G1"
XP_053995331.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_053998253.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_054007871.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_054000166.1	3	MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1	"Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism"
XP_054001844.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054015156.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_054016149.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054003900.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex"
XP_054006147.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054006247.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_054011199.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_053999679.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053996002.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053997788.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054007167.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_054005788.1	5	Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938	"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)"
XP_054009074.1	6	Reactome: R-HSA-9603798;Reactome: R-HSA-390247;Reactome: R-HSA-5684045;Reactome: R-HSA-1369062;Reactome: R-HSA-2046105;Reactome: R-HSA-2046106	"Class I peroxisomal membrane protein import";"Beta-oxidation of very long chain fatty acids";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"ABC transporters in lipid homeostasis";"Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism"
XP_054005563.1	7	KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202	"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_053996370.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_054016716.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_053997453.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053995267.1	6	Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_054010701.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054003783.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8941858;Reactome: R-HSA-68827;Reactome: R-HSA-174154;Reactome: R-HSA-187577;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-69601;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236974;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-9010553;Reactome: R-HSA-195253	"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Regulation of RUNX3 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin";"SCF(Skp2)-mediated degradation of p27/p21";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"ER-Phagosome pathway";"Regulation of PTEN stability and activity";"UCH proteinases";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex"
XP_053999066.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_054003067.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_054014850.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_054003939.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_054007744.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_054004605.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-6692;MetaCyc: PWY-7279;MetaCyc: PWY-3781;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation"
XP_054000406.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-2151201	"UCH proteinases";"HATs acetylate histones";"Transcriptional activation of mitochondrial biogenesis"
XP_054008107.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054002322.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_054007422.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054006030.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053998042.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054012025.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053997285.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_053999725.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_054010203.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054005285.1	8	Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-922;MetaCyc: PWY-7524	"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Mevalonate pathway III (archaea)"
XP_054006341.1	15	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569	"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054001124.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054006852.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_054009009.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054010153.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053996679.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053996228.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054000294.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_054005798.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310	"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Fanconi Anemia Pathway"
XP_053995575.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053999790.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053998943.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_054011425.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054004171.1	8	KEGG: 00980+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18	"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Drug metabolism - cytochrome P450"
XP_054000462.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053997838.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053999830.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_054011189.1	11	Reactome: R-HSA-174430;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-68962	"Telomere C-strand synthesis initiation";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Activation of the pre-replicative complex"
XP_054003238.1	8	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_053999776.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012418.1	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
XP_054006866.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054014920.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_054000942.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_053998463.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053996386.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054014800.1	10	Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2197563	"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH2 intracellular domain regulates transcription"
XP_054014354.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054004393.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054004875.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_054001061.1	14	MetaCyc: PWY-5080;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-5972;MetaCyc: PWY-7035	"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Stearate biosynthesis I (animals)";"(9Z)-tricosene biosynthesis"
XP_054003408.1	5	Reactome: R-HSA-446210;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16	"Synthesis of UDP-N-acetyl-glucosamine";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_053999543.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_054004335.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054004962.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_054004655.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053997233.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_054016057.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053997046.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_054006059.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054005233.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_054008351.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24	"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism"
XP_054010858.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054000227.1	19	Reactome: R-HSA-3000480;Reactome: R-HSA-8957275;Reactome: R-HSA-3000497;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-3000484;Reactome: R-HSA-432142;Reactome: R-HSA-8963901;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8964026;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471	"Scavenging by Class A Receptors";"Post-translational protein phosphorylation";"Scavenging by Class H Receptors";"LDL clearance";"LDL remodeling";"Chylomicron assembly";"Retinoid metabolism and transport";"Scavenging by Class F Receptors";"Platelet sensitization by LDL";"Chylomicron remodeling";"VLDL assembly";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Chylomicron clearance";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors"
XP_054002816.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053997133.1	3	Reactome: R-HSA-110331;Reactome: R-HSA-110330;Reactome: R-HSA-110357	"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1"
XP_054010129.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053996334.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231	"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production"
XP_054013926.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_054003950.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression"
XP_054004837.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_053996066.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_054003895.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276	"Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination"
XP_054015621.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_054003324.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054003793.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054014985.1	5	KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-5523;MetaCyc: PWY-7863	"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis"
XP_053998529.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_054005891.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_054003373.1	3	Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987	"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis"
XP_054016622.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054000470.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_054005483.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell"
XP_054014606.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-2408557	"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_054014221.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_054010405.1	52	Reactome: R-HSA-73776;Reactome: R-HSA-76071;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-8851708;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-5250924;Reactome: R-HSA-749476;Reactome: R-HSA-72086;Reactome: R-HSA-72165;Reactome: R-HSA-6781823;Reactome: R-HSA-5617472;Reactome: R-HSA-72163;Reactome: R-HSA-1834949	"RNA Polymerase II Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Dual incision in TC-NER";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase III Abortive And Retractive Initiation";"mRNA Capping";"mRNA Splicing - Minor Pathway";"Formation of TC-NER Pre-Incision Complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Major Pathway";"Cytosolic sensors of pathogen-associated DNA"
XP_054011230.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_053996627.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054010193.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054010235.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054011400.1	29	Reactome: R-HSA-6804756;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-69166;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-3371453;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-3108214;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-3371511	"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Removal of the Flap Intermediate";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of HSF1-mediated heat shock response";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"SUMOylation of DNA damage response and repair proteins";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HSF1 activation"
XP_054012641.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_054016024.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359	"Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels"
XP_054002863.1	10	KEGG: 00510+2.4.1.83;MetaCyc: PWY-7979;MetaCyc: PWY-7921;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;Reactome: R-HSA-913709;Reactome: R-HSA-4719360;MetaCyc: PWY-7922;MetaCyc: PWY-7661;Reactome: R-HSA-162699	"N-Glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"O-linked glycosylation of mucins";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein N-glycosylation (Haloferax volcanii)";"Synthesis of dolichyl-phosphate mannose"
XP_054006660.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054013886.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_054005758.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-9009391;Reactome: R-HSA-114604;Reactome: R-HSA-912631;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1660499;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-1257604	"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Extra-nuclear estrogen signaling";"GPVI-mediated activation cascade";"Regulation of signaling by CBL";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"Costimulation by the CD28 family";"Synthesis of PIPs at the plasma membrane";"G alpha (q) signalling events";"Interleukin-7 signaling";"CD28 dependent PI3K/Akt signaling";"RET signaling";"Signaling by SCF-KIT";"PIP3 activates AKT signaling"
XP_054000592.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053999750.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_054014121.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054010371.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054013727.1	12	MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;Reactome: R-HSA-3322077;MetaCyc: PWY-7343	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I"
XP_054010831.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054013639.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis"
XP_054015286.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054008658.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_054001842.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053998593.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_054016531.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5870;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5873;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-6708;MetaCyc: PWY-7230;MetaCyc: PWY-5871	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_054015186.1	4	Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540	"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1"
XP_054014774.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_054009648.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_054007051.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_054014723.1	8	KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054004633.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_054008771.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436	"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic"
XP_054001437.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_054010738.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054008391.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_054009089.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_054015404.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-5696394	"UCH proteinases";"HATs acetylate histones";"DNA Damage Recognition in GG-NER"
XP_054015134.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_054003976.1	20	MetaCyc: PWY-7854;MetaCyc: PWY-7337;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-7858;MetaCyc: PWY-7007;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7726;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7574	"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Propanoyl-coa degradation II"
XP_054010177.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_053999082.1	3	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
XP_054012782.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_053999977.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054014880.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_054008173.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_054004329.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054009919.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_054001049.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_054002581.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054011548.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_054005671.1	8	KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054010212.1	3	KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1	"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway"
XP_054003675.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054002449.1	2	KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753	"Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism"
XP_054007349.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_054014709.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054014384.1	5	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-4655427	"DNA methylation";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins"
XP_054008187.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054005342.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053998768.1	9	KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52	"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation II (Vibrio)";"Other glycan degradation"
XP_053997342.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054013870.1	4	Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085	"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_054015045.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_054013330.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053995210.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054010781.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_054015296.1	14	MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;Reactome: R-HSA-1483213;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053	"Stigma estolide biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Synthesis of PE";"Triglyceride biosynthesis";"Synthesis of PC";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II"
XP_054013041.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053996362.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053997205.1	13	MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-1660662	"Chitin degradation II (Vibrio)";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism"
XP_054016367.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054011159.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_054008061.1	6	KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;Reactome: R-HSA-975578	"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway"
XP_054001157.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253	"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_054011908.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432720	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Lysosome Vesicle Biogenesis"
XP_054015270.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053997105.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054006882.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_054003431.1	19	Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932	"Trafficking of AMPA receptors";"Ion homeostasis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"RAF activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB"
XP_054012211.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054000978.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_054005435.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_054001257.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_054011828.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_054013784.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_053998165.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_054013309.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_054006919.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_054010044.1	7	Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_054002240.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054011721.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054014730.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"mTOR signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_054016161.1	6	MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433	"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation"
XP_054004303.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_054014064.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053998861.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_054010565.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054015479.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053997477.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053999092.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_054003010.1	9	Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532	"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer"
XP_054000104.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_054011274.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-1632852	"Ub-specific processing proteases";"Macroautophagy"
XP_053996684.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054012372.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_054014336.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_054014656.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053999694.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_054016087.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-69017;Reactome: R-HSA-176408;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins"
XP_054011123.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_054011450.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-450408;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-4641258;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-349425;Reactome: R-HSA-8951664;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-6798695;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-68827;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-202424;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-8852276;Reactome: R-HSA-5668541	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Degradation of DVL";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neutrophil degranulation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"CDT1 association with the CDC6:ORC:origin complex";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Downstream TCR signaling";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"The role of GTSE1 in G2/M progression after G2 checkpoint";"TNFR2 non-canonical NF-kB pathway"
XP_054011560.1	4	MetaCyc: PWY-6281;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis"
XP_053999700.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_054005708.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053996082.1	31	MetaCyc: PWY-5971;MetaCyc: PWY-6519;Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-7858;Reactome: R-HSA-199220;MetaCyc: PWY-7746;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-7664;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;MetaCyc: PWY-5989;MetaCyc: PWY-5142;MetaCyc: PWY-7388;MetaCyc: PWY-5994;MetaCyc: PWY-5147;Reactome: R-HSA-75105;MetaCyc: PWY-7723;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-8049;MetaCyc: PWY-5966-1;MetaCyc: PWY-6113;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWY-5367;MetaCyc: PWY-8047;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5366	"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"8-amino-7-oxononanoate biosynthesis I";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"(5Z)-dodecenoate biosynthesis II";"Vitamin B5 (pantothenate) metabolism";"Mycobacterial sulfolipid biosynthesis";"";"Gondoate biosynthesis (anaerobic)";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Stearate biosynthesis II (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Fatty acyl-CoA biosynthesis";"Bacterial bioluminescence";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"Petroselinate biosynthesis";"Bryostatin biosynthesis";"Biotin metabolism";"Palmitoleate biosynthesis II (plants and bacteria)"
XP_053998992.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756	"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation"
XP_054010544.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_054005986.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_053997986.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_054014454.1	27	Reactome: R-HSA-9609690;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214	"HCMV Early Events";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear import of Rev protein";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins"
XP_053996486.1	6	Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"Circadian Clock";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_054002091.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_054004435.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_054000356.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_054008785.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"MHC class II antigen presentation"
XP_054014564.1	3	KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491	"Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation"
XP_054016844.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_054001022.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053999592.1	4	Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889	"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes"
XP_054015384.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_054010320.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_054005685.1	9	KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52	"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation"
XP_054006589.1	6	MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606	"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation II"
XP_054016587.1	3	KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)"
XP_054014045.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054011734.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054010954.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054001673.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053997478.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947	"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_054011325.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_054001755.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053999470.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_054000935.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_054001853.1	9	Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-166208	"mTOR signalling";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Neutrophil degranulation";"mTORC1-mediated signalling"
XP_054000362.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_054014479.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes"
XP_053999513.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054004477.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes"
XP_054000912.1	29	Reactome: R-HSA-75955;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-72086;Reactome: R-HSA-73863;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-167162	"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Capping";"RNA Polymerase I Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape"
XP_054003424.1	19	Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-6802955;Reactome: R-HSA-5578775;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-438066;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9617324	"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion homeostasis";"HSF1-dependent transactivation";"RAF activation";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_054008188.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_054015545.1	9	Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1;Reactome: R-HSA-70263;MetaCyc: PWY-8086;MetaCyc: PWY-6146	"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_054004516.1	4	Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497	"ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_054013541.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_054011786.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_054001829.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_054008451.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_054013951.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_054013176.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_054000082.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_054001258.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-5080	"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I"
XP_054009172.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_054001697.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_054012539.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_054012968.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_054005620.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053999279.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_054007816.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_054015890.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59	"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism"
XP_054005303.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053996254.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053999978.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_054010178.1	1	Reactome: R-HSA-6804754	"Regulation of TP53 Expression"
XP_054005970.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054014286.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_054006599.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_054000983.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053997695.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_054009589.1	7	MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_054013821.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_054010737.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053996154.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_054010629.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054001959.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_054000739.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053997353.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054001438.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053996470.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053998614.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_054008231.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054016410.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins"
XP_054008835.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_054008375.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167	"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol"
XP_054005996.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054008989.1	15	Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-5467333;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-5689896;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348	"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Ovarian tumor domain proteases";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex"
XP_053999486.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053997996.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_054015121.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-6453;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerolipid metabolism";"Synthesis of PA";"Stigma estolide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis I"
XP_054015759.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_054000700.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_054005757.1	19	Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-5627123;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-5625970;Reactome: R-HSA-428543;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-5663220;Reactome: R-HSA-4420097;Reactome: R-HSA-5626467;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-8950505;Reactome: R-HSA-114604	"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"DCC mediated attractive signaling";"RHO GTPases activate PAKs";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"RHO GTPases activate KTN1";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate Formins";"VEGFA-VEGFR2 Pathway";"RHO GTPases activate IQGAPs";"EGFR downregulation";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"GPVI-mediated activation cascade"
XP_054016746.1	5	Reactome: R-HSA-1169408;Reactome: R-HSA-6804756;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555;Reactome: R-HSA-936440	"ISG15 antiviral mechanism";"Regulation of TP53 Activity through Phosphorylation";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation";"Negative regulators of DDX58/IFIH1 signaling"
XP_054001974.1	5	KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00600+3.2.1.22	"Galactose metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation";"Sphingolipid metabolism"
XP_054007941.1	12	KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-5655302;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-194840	"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Signaling by FGFR1 in disease";"Human papillomavirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Thermogenesis";"Rho GTPase cycle"
XP_054002422.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_054006172.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_054010653.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053999104.1	2	Reactome: R-HSA-6807505;Reactome: R-HSA-72163	"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway"
XP_054004671.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_054011390.1	5	MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-5531;KEGG: 00860+4.1.1.37	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Porphyrin and chlorophyll metabolism"
XP_054001803.1	6	MetaCyc: PWY-7382;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780	"Lipoate biosynthesis and incorporation IV (yeast)";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism";"Lipoic acid metabolism";"Biotin transport and metabolism"
XP_054006441.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607	"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends"
XP_054012550.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_054012940.1	6	Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020	"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation";"Cristae formation";"Photosynthesis";"ATP biosynthesis";"Mitochondrial protein import"
XP_054002526.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053996513.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_054011796.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053998035.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054009647.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_054011836.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening"
XP_054013728.1	12	MetaCyc: PWY-7817;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00500+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7343;Reactome: R-HSA-3322077	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis"
XP_054014134.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_054003638.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-975957	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_054001491.1	14	Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-205043;Reactome: R-HSA-6798695;Reactome: R-HSA-1474228;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948	"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NRIF signals cell death from the nucleus";"Neutrophil degranulation";"Degradation of the extracellular matrix";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_054006117.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_054015032.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_054006559.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_054010984.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_054011609.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_054005546.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053996552.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054006469.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection"
XP_054001785.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053997724.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053999284.1	4	Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_054000780.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_054015800.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_054005724.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_054005773.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053997773.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_054005655.1	10	Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41	"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism"
XP_053996194.1	9	Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135	"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER"
XP_054005335.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_054005962.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_054003040.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053995449.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_054007449.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053996566.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_054010014.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_054008930.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053998029.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_054005956.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_054005171.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_054004838.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053997956.1	20	Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616	"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by REV1";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_054013100.1	13	MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1;MetaCyc: PWY-7112;MetaCyc: PWY-2261;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7533;Reactome: R-HSA-196836;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842	"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism";"4-hydroxy-2-nonenal detoxification";"Ascorbate glutathione cycle";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II"
XP_053996321.1	56	Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-4641258;Reactome: R-HSA-5658442;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-4608870;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-69017;Reactome: R-HSA-75815;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-8854050;Reactome: R-HSA-9020702;Reactome: R-HSA-5610783;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-1236974;Reactome: R-HSA-2467813;Reactome: R-HSA-9010553;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5668541;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-174084;Reactome: R-HSA-211733;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-68827;Reactome: R-HSA-174154	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"Neddylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Degradation of DVL";"Regulation of RAS by GAPs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"Asymmetric localization of PCP proteins";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"CDK-mediated phosphorylation and removal of Cdc6";"Ubiquitin-dependent degradation of Cyclin D";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"Hedgehog 'on' state";"G2/M Checkpoints";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Interleukin-1 signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"ER-Phagosome pathway";"Separation of Sister Chromatids";"Regulation of expression of SLITs and ROBOs";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"TNFR2 non-canonical NF-kB pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDT1 association with the CDC6:ORC:origin complex";"APC/C:Cdc20 mediated degradation of Securin"
XP_053997171.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_054000654.1	6	Reactome: R-HSA-2173788;MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-8939902	"Downregulation of TGF-beta receptor signaling";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity"
XP_054006260.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_054009509.1	13	Reactome: R-HSA-2132295;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-182218;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-8866427	"MHC class II antigen presentation";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD8 Down-regulation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"LDL clearance";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation"
XP_054005377.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054000823.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_054010635.1	7	Reactome: R-HSA-3000171;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178	"Non-integrin membrane-ECM interactions";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans"
XP_054011973.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_054011350.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_054006574.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_054008481.1	3	MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway"
XP_053996227.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_054006160.1	16	MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5537;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00640+6.2.1.4;KEGG: 00020+6.2.1.4;MetaCyc: PWY-7384;MetaCyc: PWY-5749;MetaCyc: PWY-5538	"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Itaconate degradation";"Pyruvate fermentation to acetate VI"
XP_054001288.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_054012141.1	4	KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221	"Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis"
XP_054016222.1	9	Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135	"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"MAP2K and MAPK activation"
XP_054015985.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053999406.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_054003407.1	5	MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_054012576.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_054004046.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_054013139.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053999136.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_054004295.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971	"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation"
XP_054007319.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_054012743.1	8	MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00620+1.1.1.27	"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Propanoate metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism"
XP_053998822.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379	"ECM proteoglycans";"Integrin cell surface interactions";"Syndecan interactions";"Molecules associated with elastic fibres"
XP_053999043.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053995319.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_054004403.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053998003.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_054003457.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_054008108.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_054001231.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_054011518.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_054003068.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_054014262.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_054001401.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054002640.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054006843.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_054009949.1	42	Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-3214842;Reactome: R-HSA-110330;Reactome: R-HSA-5578749;Reactome: R-HSA-912446;Reactome: R-HSA-427413;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-201722;Reactome: R-HSA-2559582;Reactome: R-HSA-1912408;Reactome: R-HSA-110328;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-2559580;Reactome: R-HSA-5693607;Reactome: R-HSA-5617472;Reactome: R-HSA-3214815;Reactome: R-HSA-977225;Reactome: R-HSA-5625886;Reactome: R-HSA-606279;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-5250924;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-1221632	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"DNA methylation";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"HDMs demethylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"Transcriptional regulation by small RNAs";"Meiotic recombination";"NoRC negatively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"HATs acetylate histones";"PRC2 methylates histones and DNA";"Formation of the beta-catenin:TCF transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"Pre-NOTCH Transcription and Translation";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"Oxidative Stress Induced Senescence";"Processing of DNA double-strand break ends";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDACs deacetylate histones";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Deposition of new CENPA-containing nucleosomes at the centromere";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"Meiotic synapsis"
XP_054000776.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_054001131.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054014971.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053996184.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054	"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway"
XP_053998966.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053999294.1	7	KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"Thermogenesis";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_054000790.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_054005383.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053998542.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_054006530.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_054011674.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482	"NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events"
XP_054001795.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis"
XP_054011300.1	2	KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111	"Fatty acid degradation";"Mitochondrial L-carnitine shuttle"
XP_054001893.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053995765.1	3	MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20	"Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism"
XP_053995863.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_054001835.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_054015696.1	4	MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483	"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide degradation (generic)"
XP_053998316.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_054004429.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_054007581.1	24	Reactome: R-HSA-420092;Reactome: R-HSA-418594;Reactome: R-HSA-400042;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-416476;Reactome: R-HSA-418555;Reactome: R-HSA-392170	"Glucagon-type ligand receptors";"G alpha (i) signalling events";"Adrenaline,noradrenaline inhibits insulin secretion";"Presynaptic function of Kainate receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (q) signalling events";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12"
XP_054005826.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_054006248.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053995610.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053995581.1	11	Reactome: R-HSA-109704;Reactome: R-HSA-1660499;Reactome: R-HSA-5668599;Reactome: R-HSA-1660517;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-1660514	"PI3K Cascade";"Synthesis of PIPs at the plasma membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Macroautophagy";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the Golgi membrane"
XP_054013474.1	3	MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315	"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol"
XP_054001812.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_054004285.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_054006148.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053996043.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_054005906.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_054013423.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_054011339.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_054007268.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Neutrophil degranulation";"Glycerolipid metabolism"
XP_054011879.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_054013991.1	14	Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569	"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_054008491.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_054012611.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription"
XP_054015850.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_054015304.1	10	MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Methane metabolism";"Fructose and mannose metabolism"
XP_054005787.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_054010807.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_054003601.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_053997063.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_054000809.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053997787.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_054010683.1	6	Reactome: R-HSA-6811438;Reactome: R-HSA-5620916;Reactome: R-HSA-6807878;Reactome: R-HSA-1445148;Reactome: R-HSA-6811440;Reactome: R-HSA-264876	"Intra-Golgi traffic";"VxPx cargo-targeting to cilium";"COPI-mediated anterograde transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Retrograde transport at the Trans-Golgi-Network";"Insulin processing"
XP_053997605.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"