Accession_ID	Pathway_Count	Pathway_IDs	Pathway_Names
XP_053971074.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053983115.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053984979.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053971098.1	18	KEGG: 00260+1.8.1.4;Reactome: R-HSA-71064;Reactome: R-HSA-70268;KEGG: 00620+1.8.1.4;KEGG: 00010+1.8.1.4;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00280+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00380+1.8.1.4;Reactome: R-HSA-389661;KEGG: 00020+1.8.1.4;KEGG: 00310+1.8.1.4;Reactome: R-HSA-70895;KEGG: 00640+1.8.1.4;MetaCyc: PWY-5046;Reactome: R-HSA-6783984;Reactome: R-HSA-204174	"Glycine, serine and threonine metabolism";"Lysine catabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Valine, leucine and isoleucine degradation";"Signaling by Retinoic Acid";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053979045.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053994240.1	17	Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5789;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2	"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Propanoate metabolism"
XP_053990047.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053981696.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053974613.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_053993663.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053989435.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053972794.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053972778.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_053990415.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053973571.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_053977965.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-399997	"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion"
XP_053979417.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053990873.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053986674.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053991961.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_053986698.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053990204.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-182218	"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation"
XP_053972137.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053976096.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053970646.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199	"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation"
XP_053989149.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053982957.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053982574.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_053984426.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053993597.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053980979.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053983791.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053985274.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_053977827.1	1	Reactome: R-HSA-389661	"Glyoxylate metabolism and glycine degradation"
XP_053973778.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053993767.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_053992339.1	5	Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-193048;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_053974285.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053983656.1	3	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
XP_053980345.1	2	Reactome: R-HSA-975634;Reactome: R-HSA-192456	"Retinoid metabolism and transport";"Digestion of dietary lipid"
XP_053994514.1	4	KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26;Reactome: R-HSA-1971475	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053980228.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053994175.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053971061.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis"
XP_053978213.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053979738.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_053981558.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053979348.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation"
XP_053982561.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053993339.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053988335.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053994242.1	17	MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-196780;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-5789;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2	"Candicidin biosynthesis";"Fatty acid biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Pyruvate metabolism"
XP_053971395.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_053972058.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053977840.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053984228.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_053984345.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053991557.1	1	Reactome: R-HSA-5626467	"RHO GTPases activate IQGAPs"
XP_053986661.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053986556.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053983846.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053974922.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053976664.1	8	Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-5099900;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"WNT5A-dependent internalization of FZD4";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_053970285.1	3	MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)"
XP_053985496.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053992919.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979531.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_053971754.1	33	Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-8939236;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-69656;Reactome: R-HSA-73776;Reactome: R-HSA-69273;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-76042	"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053970717.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053978784.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_053993570.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_053984200.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053971294.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_053980512.1	14	KEGG: 00564+2.3.1.51;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)"
XP_053988234.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053976810.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_053971278.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981356.1	3	KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_053984244.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_053981466.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes"
XP_053980381.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053991188.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053984381.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_053988588.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053984193.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053980244.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_053985719.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053975888.1	12	KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4	"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Sulfur metabolism";"Purine metabolism";"Selenocompound metabolism"
XP_053986775.1	20	MetaCyc: PWY-7606;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7337;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7288	"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoate metabolism";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)"
XP_053985949.1	1	Reactome: R-HSA-9022692	"Regulation of MECP2 expression and activity"
XP_053975180.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_053984512.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053985078.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053975091.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053986358.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053971116.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053979192.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_053989871.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053991453.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053977390.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053973254.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_053988600.1	3	Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296	"HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome"
XP_053991363.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053971476.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053986055.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053984510.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053992806.1	3	Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-7286	"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis"
XP_053985375.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053978641.1	13	Reactome: R-HSA-6798695;Reactome: R-HSA-2206308;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-2022857;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23	"Neutrophil degranulation";"MPS IV - Morquio syndrome B";"Sialic acid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Defective NEU1 causes sialidosis";"Keratan sulfate degradation";"HS-GAG degradation";"Galactose metabolism"
XP_053986491.1	5	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway"
XP_053986939.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053982251.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053984202.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053991249.1	40	Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-6782135;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"Dual incision in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_053976478.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053975068.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053975554.1	4	MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975	"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate"
XP_053986266.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053982709.1	4	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER"
XP_053989905.1	5	MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523	"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
XP_053970631.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053979203.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053993806.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053982396.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053984024.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053994305.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053995145.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053971068.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053972106.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_053989734.1	3	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_053972495.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053985970.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053981123.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_053983054.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase"
XP_053976133.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558	"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_053990900.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones"
XP_053993693.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation"
XP_053992567.1	16	Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-194840;Reactome: R-HSA-1257604;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-6811558;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530;Reactome: R-HSA-388841	"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"Regulation of signaling by CBL";"Rho GTPase cycle";"PIP3 activates AKT signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family"
XP_053987144.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053994099.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053989300.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053975476.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653	"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_053973106.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053995060.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053982568.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053987100.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_053972051.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053981375.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_053985268.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_053973764.1	26	Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-9018519;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-933541;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-210744;Reactome: R-HSA-3899300;Reactome: R-HSA-400253	"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Estrogen-dependent gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"TRAF6 mediated IRF7 activation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors";"Circadian Clock"
XP_053974002.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053982774.1	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Anandamide biosynthesis I"
XP_053989302.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053993797.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053994902.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053983591.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053992951.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053995062.1	10	MetaCyc: PWY-7411;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051	"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_053973578.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053974044.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053988444.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_053987102.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053981094.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949	"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA"
XP_053978034.1	3	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_053971180.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053974999.1	13	KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation"
XP_053988031.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642	"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_053974303.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_053974000.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053970303.1	11	Reactome: R-HSA-388841;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-391160;Reactome: R-HSA-389948;Reactome: R-HSA-912694;Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-432142;Reactome: R-HSA-210990;Reactome: R-HSA-877312	"Costimulation by the CD28 family";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signal regulatory protein family interactions";"PD-1 signaling";"Regulation of IFNA signaling";"GPVI-mediated activation cascade";"Interleukin-37 signaling";"Platelet sensitization by LDL";"PECAM1 interactions";"Regulation of IFNG signaling"
XP_053980434.1	4	MetaCyc: PWY-7807;Reactome: R-HSA-71737;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1	"Glyphosate degradation III";"Pyrophosphate hydrolysis";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation"
XP_053970431.1	3	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843	"Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis"
XP_053995029.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053983774.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053985972.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053992797.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053985291.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053976694.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053979809.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053981825.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053978703.1	2	Reactome: R-HSA-8849473;Reactome: R-HSA-6791226	"PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053991077.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_053973376.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_053988013.1	15	Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_053988310.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_053977883.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-445355	"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction"
XP_053970901.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_053993353.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_053979088.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053981261.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053993050.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_053986609.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053974638.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_053993772.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053990432.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053987869.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053980710.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_053985751.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_053980085.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984940.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053984163.1	6	Reactome: R-HSA-9022537;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781	"Loss of MECP2 binding ability to the NCoR/SMRT complex";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones";"HCMV Early Events";"PPARA activates gene expression"
XP_053978150.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_053974028.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053994279.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053975061.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053987657.1	5	MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;KEGG: 00620+4.1.1.32	"Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_053973665.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053970446.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949664	"Mitochondrial protein import";"Processing of SMDT1"
XP_053985997.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053974325.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_053994001.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053984942.1	2	Reactome: R-HSA-6803157;Reactome: R-HSA-6798695	"Antimicrobial peptides";"Neutrophil degranulation"
XP_053982675.1	2	Reactome: R-HSA-444821;Reactome: R-HSA-418555	"Relaxin receptors";"G alpha (s) signalling events"
XP_053991181.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053988788.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053972950.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053994387.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053979746.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053979713.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053982838.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase"
XP_053975098.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053990387.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053990928.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053983675.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053985071.1	3	Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_053987753.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053975074.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053988312.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_053983130.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053976354.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053974173.1	5	Reactome: R-HSA-186763;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471	"Downstream signal transduction";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"
XP_053977185.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053993770.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_053984927.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_053990430.1	3	Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport"
XP_053976795.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053994156.1	17	Reactome: R-HSA-8953750;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1912408;Reactome: R-HSA-139915;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-9616222;Reactome: R-HSA-113501;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-2559580	"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Pre-NOTCH Transcription and Translation";"Activation of PUMA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Transcriptional regulation of granulopoiesis";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Oxidative Stress Induced Senescence"
XP_053989410.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053980712.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053982366.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053985884.1	6	Reactome: R-HSA-5620916;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_053975881.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053971857.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_053973984.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053982532.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053985850.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053975782.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053975938.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053994674.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053994698.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_053985232.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053983109.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053986632.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053990409.1	7	MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I"
XP_053986047.1	3	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984	"One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation"
XP_053991013.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053981427.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053979562.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053986240.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_053984697.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053983532.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053993321.1	13	Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-167590	"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef Mediated CD4 Down-regulation"
XP_053985604.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053975601.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053976201.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053991428.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_053981683.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053986204.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053988092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053985926.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053979529.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053993864.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_053984811.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053985640.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985723.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053976718.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053987721.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053986020.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053989572.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053986323.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053988393.1	19	MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5538;MetaCyc: PWY-5537;Reactome: R-HSA-75105;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;Reactome: R-HSA-163765	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"Propanoate metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"ChREBP activates metabolic gene expression"
XP_053978184.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_053988181.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_053974573.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053988090.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
XP_053977603.1	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes"
XP_053971401.1	1	Reactome: R-HSA-9018519	"Estrogen-dependent gene expression"
XP_053975469.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053993905.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053988909.1	15	Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2467813	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids"
XP_053976863.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053990661.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053982530.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053971716.1	7	Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69231	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin D associated events in G1"
XP_053972308.1	7	Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;MetaCyc: PWY-3561	"Synthesis of PA";"Role of phospholipids in phagocytosis";"Glycerophospholipid metabolism";"Synthesis of PG";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III"
XP_053971743.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053972897.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053971946.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_053971913.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053985627.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_053991581.1	9	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol"
XP_053985230.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053991226.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053986630.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053982614.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053992905.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053985119.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053979560.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053986175.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053981314.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053977541.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053973633.1	13	Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482	"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events"
XP_053973506.1	1	Reactome: R-HSA-75153	"Apoptotic execution phase"
XP_053982860.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053980467.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053982379.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053979830.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053984670.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053982168.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053987500.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053973418.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053971608.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053984186.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053977338.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053972633.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053986921.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053985705.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053983860.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053978049.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053980135.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_053981523.1	12	MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00630+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5132	"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Lupulone and humulone biosynthesis"
XP_053980670.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_053990358.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways"
XP_053981151.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_053972418.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053973023.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053993435.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_053988272.1	6	Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-5664;KEGG: 00790+4.2.3.12;MetaCyc: PWY-6983	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis"
XP_053977866.1	14	MetaCyc: PWY-5057;MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00270+2.6.1.42;KEGG: 00280+2.6.1.42;KEGG: 00966+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5103;MetaCyc: PWY-5104;Reactome: R-HSA-70895;MetaCyc: PWY-5076;MetaCyc: PWY-5101;MetaCyc: PWY-5078	"L-valine degradation II";"L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine degradation";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis III";"L-isoleucine biosynthesis IV";"Branched-chain amino acid catabolism";"L-leucine degradation III";"L-isoleucine biosynthesis II";"L-isoleucine degradation II"
XP_053974039.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053990775.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053989663.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053978994.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053979057.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053982191.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_053977959.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_053989339.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053972194.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053980672.1	2	MetaCyc: PWY-6558;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis"
XP_053994939.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_053990319.1	5	Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-201722;Reactome: R-HSA-1266695	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling"
XP_053988653.1	16	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053976299.1	6	Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_053987139.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053980833.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053994266.1	3	Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999	"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle"
XP_053973216.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053973243.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053972369.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053988077.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053975408.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053992610.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053982862.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053988968.1	3	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism";"TP53 Regulates Metabolic Genes"
XP_053992923.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053972243.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053972216.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_053971580.1	6	KEGG: 00760+6.3.5.1;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_053988843.1	24	Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-418555	"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"G alpha (s) signalling events"
XP_053984672.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_053987502.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053977035.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053988816.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols"
XP_053987017.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053994055.1	11	KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5693565	"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053993288.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053979250.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053987688.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053972322.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-194840	"RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle"
XP_053970660.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053986900.1	5	Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757	"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation"
XP_053978373.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053992635.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_053978070.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053980649.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053994668.1	4	Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053992170.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053970462.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053979760.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053981587.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053992878.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053982730.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053986944.1	12	KEGG: 04926+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-193648;Reactome: R-HSA-5655302;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"NRAGE signals death through JNK";"Signaling by FGFR1 in disease";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis"
XP_053993025.1	10	MetaCyc: PWY-3821;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344	"D-galactose detoxification";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis"
XP_053976711.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053974429.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_053988029.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053984112.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053991234.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053977010.1	5	Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3	"Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism"
XP_053970773.1	11	Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_053992412.1	26	Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-69205;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-174417;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6804114;Reactome: R-HSA-8866654;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-1362277;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-6782135;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-4615885;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320	"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G1/S-Specific Transcription";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching";"Translesion synthesis by POLI";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"E3 ubiquitin ligases ubiquitinate target proteins";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Transcription of E2F targets under negative control by DREAM complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Dual incision in TC-NER";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"SUMOylation of DNA replication proteins";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH"
XP_053972280.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_053971543.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053988880.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878	"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport"
XP_053989050.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_053984667.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053993170.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053972087.1	5	Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170	"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_053989353.1	3	MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12	"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism"
XP_053980112.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053971699.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_053993686.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053994953.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_053976195.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053988639.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_053982340.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_053972433.1	6	Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-77387	"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Insulin receptor recycling"
XP_053978125.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053977524.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053990668.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_053980593.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_053982304.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053989052.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053991644.1	17	KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167287;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053994817.1	13	MetaCyc: PWY-6842;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;MetaCyc: PWY-2261;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;Reactome: R-HSA-196836;Reactome: R-HSA-156590	"Glutathione-mediated detoxification II";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Ascorbate glutathione cycle";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation"
XP_053975154.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation"
XP_053980110.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208	"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling"
XP_053978389.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053980763.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053980818.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053988060.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_053973849.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053988363.1	12	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis"
XP_053983327.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053974350.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053975499.1	9	Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex"
XP_053977425.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053973925.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189	"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins"
XP_053985314.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053970350.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053984239.1	4	KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32;MetaCyc: PWY-8051	"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_053987488.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors"
XP_053973659.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053972867.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053984818.1	52	Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091	"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells"
XP_053970460.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053985006.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053982732.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053984110.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053975582.1	5	Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053972282.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053979473.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053990817.1	4	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation"
XP_053988882.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053981852.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053971780.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880	"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases"
XP_053992281.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053990609.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053981230.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053981627.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053975913.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053993300.1	6	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053978290.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053976220.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_053993197.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_053982198.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053994474.1	4	Reactome: R-HSA-1474228;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320	"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation"
XP_053976042.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053993344.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053971422.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053974692.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053985440.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053992344.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656121	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLI"
XP_053993526.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053975333.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053983198.1	32	Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72203;Reactome: R-HSA-72086	"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping"
XP_053988961.1	2	Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24	"Lysosomal oligosaccharide catabolism";"Other glycan degradation"
XP_053975401.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053985404.1	4	MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Glycine, serine and threonine metabolism"
XP_053983174.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053976985.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053977403.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053974690.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053981604.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_053983414.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053994461.1	3	KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis"
XP_053986156.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053991157.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053990114.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053981723.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_053981640.1	2	Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053989134.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053978805.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053972399.1	4	Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889	"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes"
XP_053975647.1	3	Reactome: R-HSA-193681;Reactome: R-HSA-1660662;Reactome: R-HSA-5626978	"Ceramide signalling";"Glycosphingolipid metabolism";"TNFR1-mediated ceramide production"
XP_053994296.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)"
XP_053979131.1	13	Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5	"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)"
XP_053981850.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053990296.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982414.1	4	KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494	"Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV"
XP_053981479.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053976004.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_053981232.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053993302.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053988557.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_053978971.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053994575.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053983205.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053986928.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053991386.1	10	Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053987744.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053990351.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053981158.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053985427.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053988360.1	12	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Activation of AMPK downstream of NMDARs";"PI3K-Akt signaling pathway"
XP_053993875.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053988063.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053993446.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053972279.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053978128.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053971214.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053990665.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053976174.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_053989352.1	3	KEGG: 00680+3.1.2.12;Reactome: R-HSA-156590;MetaCyc: PWY-1801	"Methane metabolism";"Glutathione conjugation";"Formaldehyde oxidation II (glutathione-dependent)"
XP_053986171.1	4	MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75	"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053982220.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053980760.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053992901.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053972615.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053977788.1	57	Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641258	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL"
XP_053979649.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_053994952.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053980146.1	15	Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-167238;Reactome: R-HSA-167152	"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053980113.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053971527.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053984146.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_053984113.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053977226.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053984760.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053992875.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_053987725.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053992446.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053971542.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053970772.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053979593.1	18	MetaCyc: PWY-7383;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00401+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00950+2.6.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Partial TCA cycle (obligate autotrophs)";"Sulfolactate degradation III";"Tyrosine metabolism";"(R)-cysteate degradation";"Novobiocin biosynthesis";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Isoquinoline alkaloid biosynthesis"
XP_053979470.1	12	Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507	"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus"
XP_053982027.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_053973615.1	13	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human papillomavirus infection"
XP_053993901.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053974257.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053975011.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053970463.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053971196.1	5	Reactome: R-HSA-75896;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_053988185.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053978847.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_053975605.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053982733.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053988329.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_053982985.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-418217	"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"G alpha (s) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta"
XP_053983004.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053993325.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053982247.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053985547.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053988883.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-201722	"Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex"
XP_053971540.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053977046.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-606279	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053972283.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053977013.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_053983316.1	25	Reactome: R-HSA-8941858;Reactome: R-HSA-8939246;Reactome: R-HSA-8941333;Reactome: R-HSA-8949275;Reactome: R-HSA-8941284;Reactome: R-HSA-8939247;Reactome: R-HSA-8934593;Reactome: R-HSA-8939256;Reactome: R-HSA-8940973;Reactome: R-HSA-8941326;Reactome: R-HSA-8951911;Reactome: R-HSA-8941332;Reactome: R-HSA-8939245;Reactome: R-HSA-8939902;Reactome: R-HSA-8939243;Reactome: R-HSA-8951936;Reactome: R-HSA-8877330;Reactome: R-HSA-8931987;Reactome: R-HSA-9018519;Reactome: R-HSA-8878166;Reactome: R-HSA-8939242;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-8935964;Reactome: R-HSA-8936459	"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates osteoblast differentiation";"RUNX2 regulates bone development";"RUNX3 regulates RUNX1-mediated transcription";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates transcription of genes involved in BCR signaling";"Regulation of RUNX2 expression and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX3 regulates p14-ARF";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates estrogen receptor mediated transcription";"Estrogen-dependent gene expression";"Transcriptional regulation by RUNX2";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053986706.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053982269.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053984815.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053980729.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053976205.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053985569.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053983222.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_053979966.1	3	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020;KEGG: 00860+1.16.3.1	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import";"Porphyrin and chlorophyll metabolism"
XP_053988362.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053984729.1	6	Reactome: R-HSA-2046105;Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-5684045;Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053991484.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053989053.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053983269.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053982316.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_053980762.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053982040.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053994950.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_053973156.1	9	MetaCyc: PWY-6703;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-5664;MetaCyc: PWY-5663;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-6147;MetaCyc: PWY-6983	"Preq0 biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis"
XP_053987441.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053990764.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053972900.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053983406.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053981643.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053972099.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053974693.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053991959.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390450	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Folding of actin by CCT/TriC"
XP_053994051.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053981482.1	2	Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286	"Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism"
XP_053987034.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_053990495.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053979497.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_053992517.1	16	Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-388841;Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-194840;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-9009391;Reactome: R-HSA-416476	"Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"RET signaling";"Costimulation by the CD28 family";"Interleukin-7 signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Rho GTPase cycle";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events"
XP_053971779.1	3	Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310	"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway"
XP_053978102.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053991035.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network"
XP_053974549.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053982406.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053986618.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593	"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity"
XP_053995010.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053971423.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053993517.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_053994764.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053986301.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053983711.1	6	MetaCyc: PWY-6854;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;Reactome: R-HSA-9615017;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"
XP_053985218.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053981599.1	5	Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_053975912.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053981155.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053986659.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053994578.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053983208.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053980131.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_053995012.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053975704.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053986925.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053988995.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053971986.1	7	Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053982559.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053981917.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053980954.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053980577.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981337.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053993207.1	52	Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6803529;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-167162	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"FGFR2 alternative splicing";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape"
XP_053975033.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (i) signalling events"
XP_053982208.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053978808.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_053978397.1	12	MetaCyc: PWY-7343;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527	"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Glycogen synthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Sucrose biosynthesis II";"Stachyose degradation"
XP_053971059.1	14	MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619	"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis"
XP_053986867.1	14	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation"
XP_053978144.1	4	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)"
XP_053981722.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053977402.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053991918.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053990594.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053990578.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053991748.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053976732.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_053984131.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053992431.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053975059.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053988093.1	7	Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-381033	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones"
XP_053988390.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053985337.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_053975315.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053985722.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053973921.1	4	Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295	"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation"
XP_053977644.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_053989814.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053993241.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979811.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053983606.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053981416.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling"
XP_053980790.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053988107.1	5	KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5189	"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)"
XP_053983533.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053984790.1	6	KEGG: 00500+3.2.1.1;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-5067	"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)"
XP_053991507.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053986633.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053979563.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053991012.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053980529.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053975935.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483	"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"HCMV Early Events";"Activation of AMPK downstream of NMDARs"
XP_053987424.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053977421.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053989589.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_053975986.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-936837	"Neutrophil degranulation";"Ion transport by P-type ATPases"
XP_053986418.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053985233.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053972008.1	5	Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex"
XP_053971910.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053971166.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053971740.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053976191.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053995086.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053993631.1	30	Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-2564830;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5696400	"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER"
XP_053977234.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053986178.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053976080.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053986347.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053983907.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053972305.1	7	KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4	"Glycerophospholipid metabolism";"Synthesis of PG";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism"
XP_053971912.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053979996.1	7	Reactome: R-HSA-165181;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-8854214	"Inhibition of TSC complex formation by PKB";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs"
XP_053979793.1	3	Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17	"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism"
XP_053978121.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053977602.1	13	MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227	"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_053991524.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053993908.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_053988392.1	19	Reactome: R-HSA-163765;KEGG: 00020+2.3.3.8;Reactome: R-HSA-6798695;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-5172;KEGG: 00640+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-5537;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384	"ChREBP activates metabolic gene expression";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"Acetyl-coa biosynthesis III (from citrate)";"Propanoate metabolism";"Fatty acyl-CoA biosynthesis";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)"
XP_053982907.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053985720.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053985616.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053992631.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053985643.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053981176.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053990254.1	9	Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"DNA Damage Recognition in GG-NER";"Neddylation";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER"
XP_053985482.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053986243.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053986216.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053986737.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053986322.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053983299.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445	"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation"
XP_053990794.1	4	Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_053990778.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_053980830.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053973022.1	6	KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33;KEGG: 00720+4.2.1.3	"Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis";"Carbon fixation pathways in prokaryotes"
XP_053983165.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053993438.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053976532.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases";"Degradation of AXIN"
XP_053989662.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053970958.1	1	Reactome: R-HSA-6804759	"Regulation of TP53 Activity through Association with Co-factors"
XP_053988273.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053970597.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053982380.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053977745.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053991331.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053994571.1	7	MetaCyc: PWY-7185;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.15;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7198	"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_053983201.1	8	Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091	"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching"
XP_053985708.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053984138.1	8	Reactome: R-HSA-5173105;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;Reactome: R-HSA-5083633	"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1"
XP_053973415.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053975540.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053983437.1	14	Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638;Reactome: R-HSA-450520;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813	"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids"
XP_053974597.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053982201.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053994778.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053984830.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053992920.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053975504.1	5	KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-380994;Reactome: R-HSA-9648895	"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_053992613.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_053994794.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053983083.1	4	MetaCyc: PWY-7375;Reactome: R-HSA-167160;Reactome: R-HSA-72086;Reactome: R-HSA-77075	"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_053987503.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053993947.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053993285.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053984673.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053979833.1	8	Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"SUMOylation of chromatin organization proteins";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_053993236.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_053994564.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053972323.1	30	Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-1170546;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-5610783;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664	"Iron uptake and transport";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Circadian Clock";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Prolactin receptor signaling";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI2 by the proteasome";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation"
XP_053987448.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053988965.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_053992922.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979672.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-212436	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway"
XP_053978367.1	4	Reactome: R-HSA-389661;MetaCyc: PWY-7382;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_053972514.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock"
XP_053980832.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053983948.1	22	KEGG: 00500+5.3.1.9;Reactome: R-HSA-6798695;Reactome: R-HSA-70171;MetaCyc: PWY-5054;Reactome: R-HSA-70263;Reactome: R-HSA-5628897;MetaCyc: PWY-5659;MetaCyc: PWY-621;KEGG: 00010+5.3.1.9;MetaCyc: PWY-5514;MetaCyc: PWY-7238;MetaCyc: PWY-7347;MetaCyc: PWY-6981;MetaCyc: PWY-3801;KEGG: 00030+5.3.1.9;MetaCyc: PWY-622;KEGG: 00520+5.3.1.9;MetaCyc: PWY-8013;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-6992;MetaCyc: PWY-5384	"Starch and sucrose metabolism";"Neutrophil degranulation";"Glycolysis";"D-sorbitol biosynthesis I";"Gluconeogenesis";"TP53 Regulates Metabolic Genes";"GDP-mannose biosynthesis";"Sucrose degradation III (sucrose invertase)";"Glycolysis / Gluconeogenesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Sucrose biosynthesis II";"Sucrose biosynthesis III";"Chitin biosynthesis";"Sucrose degradation II (sucrose synthase)";"Pentose phosphate pathway";"Starch biosynthesis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"1,5-anhydrofructose degradation";"Sucrose degradation IV (sucrose phosphorylase)"
XP_053984057.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-72731;Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-381042;Reactome: R-HSA-9633012	"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"PERK regulates gene expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053989660.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053971579.1	6	KEGG: 00760+6.3.5.1;MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;Reactome: R-HSA-196807;MetaCyc: PWY-5653	"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_053980250.1	8	MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-6664;MetaCyc: PWY-6580;MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4	"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism"
XP_053986611.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053987026.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053971391.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_053988331.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_053981378.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053975766.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_053974003.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053988403.1	7	Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-2467813	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids"
XP_053981147.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_053975140.1	16	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_053987805.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_053979535.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053980284.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-8951664	"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Neddylation"
XP_053974344.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053988548.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion"
XP_053984341.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053993692.1	4	MetaCyc: PWY-7494;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline degradation IV";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Glycine, serine and threonine metabolism"
XP_053987292.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053984731.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_053976132.1	5	Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558	"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_053984284.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053991377.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053975658.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053972474.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053988741.1	3	Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-191859	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"snRNP Assembly"
XP_053980538.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053981122.1	29	Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-6796648;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693579;KEGG: 04926+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-349425;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69541;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-6803204;Reactome: R-HSA-5693571;Reactome: R-HSA-5685938;Reactome: R-HSA-6804760;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"TP53 Regulates Transcription of DNA Repair Genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Homologous DNA Pairing and Strand Exchange";"Relaxin signaling pathway";"Meiotic recombination";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Human papillomavirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Stabilization of p53";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Nonhomologous End-Joining (NHEJ)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Methylation";"HDR through Homologous Recombination (HRR)"
XP_053994171.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053973609.1	16	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX"
XP_053988911.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053993690.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053976130.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-210745	"Nuclear Receptor transcription pathway";"Regulation of gene expression in beta cells"
XP_053994411.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053978702.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053989207.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053990399.1	7	MetaCyc: PWY-6363;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phytate degradation I"
XP_053970302.1	11	Reactome: R-HSA-909733;Reactome: R-HSA-388841;Reactome: R-HSA-432142;Reactome: R-HSA-210990;Reactome: R-HSA-877312;Reactome: R-HSA-512988;Reactome: R-HSA-391160;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-9008059;Reactome: R-HSA-114604	"Interferon alpha/beta signaling";"Costimulation by the CD28 family";"Platelet sensitization by LDL";"PECAM1 interactions";"Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signal regulatory protein family interactions";"Regulation of IFNA signaling";"PD-1 signaling";"Interleukin-37 signaling";"GPVI-mediated activation cascade"
XP_053976219.1	5	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-1362409;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols"
XP_053985973.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053981120.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053984809.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053991652.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053987103.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053986826.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-2022377	"Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins"
XP_053991827.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053972351.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053974302.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_053973114.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053983111.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_053975142.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053981075.1	11	MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;Reactome: R-HSA-446205	"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"Synthesis of GDP-mannose"
XP_053976456.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14	"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Glycosaminoglycan degradation"
XP_053994399.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8949613	"Mitochondrial protein import";"Cristae formation"
XP_053971836.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053972296.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_053971885.1	6	Reactome: R-HSA-8868766;MetaCyc: PWY-7286;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_053977961.1	6	Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592	"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1"
XP_053994706.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053995063.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667	"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_053979434.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_053970878.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053970894.1	4	KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295	"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)"
XP_053983066.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053991107.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053978855.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053994618.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053973668.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053979940.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053982255.1	3	Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-948021	"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Transport to the Golgi and subsequent modification"
XP_053986764.1	20	MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7606	"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_053974025.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053980088.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053980617.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053991093.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053971566.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053990433.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053993773.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053993976.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_053972668.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053989446.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_053973756.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-210744;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-381340	"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors";"RORA activates gene expression";"Circadian Clock";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation"
XP_053974686.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053977882.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-445355	"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction"
XP_053978645.1	3	KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158	"Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V"
XP_053975398.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053988012.1	15	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex"
XP_053975374.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_053985371.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053983133.1	4	Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-216083	"Syndecan interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Integrin cell surface interactions"
XP_053976054.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053994867.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053976798.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053974172.1	5	Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-186763	"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"Downstream signal transduction"
XP_053980746.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053977188.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053981576.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053983886.1	13	Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-167590	"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef Mediated CD4 Down-regulation"
XP_053980916.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_053987373.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053980943.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053988313.1	18	Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409	"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PS";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_053988346.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053993460.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053992677.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556	"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport"
XP_053977029.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination"
XP_053983678.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053973691.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053979927.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053983694.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053975361.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053978286.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053982835.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053994925.1	4	Reactome: R-HSA-4755609;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_053986594.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_053981295.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053979712.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053989325.1	1	KEGG: 00860+4.4.1.17	"Porphyrin and chlorophyll metabolism"
XP_053988217.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053988736.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_053984746.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_053984713.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499	"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane"
XP_053972691.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053988524.1	2	Reactome: R-HSA-4755609;Reactome: R-HSA-446199	"Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate"
XP_053974328.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053985199.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053977062.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053989856.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053987229.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053975309.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053973775.1	5	Reactome: R-HSA-381426;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-532668;Reactome: R-HSA-8957275	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation"
XP_053981364.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053988959.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053976831.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053975796.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053977270.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_053993117.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053981821.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053973358.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053971824.1	9	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315	"mTOR signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol"
XP_053984980.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053981199.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167161	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation"
XP_053970612.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053978139.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053994418.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_053973468.1	11	MetaCyc: PWY-6999;MetaCyc: PWY-6607;MetaCyc: PWY-6538;Reactome: R-HSA-8851680;KEGG: 00230+1.17.1.4;Reactome: R-HSA-74259;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-6596;MetaCyc: PWY-5497;MetaCyc: PWY-5695	"Theophylline degradation";"Guanosine nucleotides degradation I";"Caffeine degradation III (bacteria, via demethylation)";"Butyrophilin (BTN) family interactions";"Purine metabolism";"Purine catabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Adenosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Inosine 5'-phosphate degradation"
XP_053992955.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053982276.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant"
XP_053977968.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053995124.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053974612.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053983595.1	5	Reactome: R-HSA-4085001;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295	"Sialic acid metabolism";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation"
XP_053993662.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_053990872.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053977077.1	10	MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055	"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis"
XP_053992629.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053985576.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053979048.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_053972468.1	15	Reactome: R-HSA-9652282;Reactome: R-HSA-9665247;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246;Reactome: R-HSA-5637810;Reactome: R-HSA-9665245;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-9665233;Reactome: R-HSA-9665249;Reactome: R-HSA-9664565;Reactome: R-HSA-9665244;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382	"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib";"Constitutive Signaling by EGFRvIII";"Resistance of ERBB2 KD mutants to tesevatinib";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants"
XP_053978017.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-975634;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Ether lipid metabolism"
XP_053992117.1	10	MetaCyc: PWY-6554;MetaCyc: PWY-6361;MetaCyc: PWY-6372;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis"
XP_053983118.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053974435.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053988035.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_053988086.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053974923.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-6807505;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes";"Protein ubiquitination"
XP_053984177.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053993660.1	7	Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053974726.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053980738.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053990870.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053984348.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053983478.1	33	Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910	"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs"
XP_053992477.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053973491.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52	"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation"
XP_053973939.1	27	Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-5467340;KEGG: 04151+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5250924;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;KEGG: 04926+2.7.11.1;Reactome: R-HSA-399956;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5339716;Reactome: R-HSA-5610785;Reactome: R-HSA-5358752;Reactome: R-HSA-5610783;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-75815;Reactome: R-HSA-196299;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-8939902	"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"AXIN missense mutants destabilize the destruction complex";"PI3K-Akt signaling pathway";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"B-WICH complex positively regulates rRNA expression";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"CRMPs in Sema3A signaling";"Human immunodeficiency virus 1 infection";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"mTOR signaling pathway";"Misspliced GSK3beta mutants stabilize beta-catenin";"GLI3 is processed to GLI3R by the proteasome";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"Ubiquitin-dependent degradation of Cyclin D";"Beta-catenin phosphorylation cascade";"Human papillomavirus infection";"Thermogenesis";"Regulation of RUNX2 expression and activity"
XP_053983765.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053981371.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053971374.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053988338.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053972055.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053978500.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-6798695;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Neutrophil degranulation";"AURKA Activation by TPX2"
XP_053994243.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053995107.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053982478.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-1169408	"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism"
XP_053990737.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053979983.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053979735.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_053994194.1	6	Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;Reactome: R-HSA-194840;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368	"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_053988918.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-8964539	"Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism"
XP_053987049.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_053994178.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053970534.1	5	Reactome: R-HSA-936440;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-933541	"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation"
XP_053978212.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_053980348.1	5	Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-1445148	"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Neutrophil degranulation";"RAB geranylgeranylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053987978.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053976709.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053980225.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053984738.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053994870.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053975651.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053970610.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_053984982.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053980177.1	6	KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;MetaCyc: PWY-7717;Reactome: R-HSA-71240;MetaCyc: PWY-7765;MetaCyc: PWY-6309	"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)"
XP_053974288.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_053983096.1	10	Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-400206	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha"
XP_053994984.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053979193.1	2	KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557	"T cell receptor signaling pathway";"Signaling by SCF-KIT"
XP_053986019.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053983671.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053986778.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053977909.1	17	Reactome: R-HSA-1433557;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-6796648;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-69473	"Signaling by SCF-KIT";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Transcription of DNA Repair Genes";"Human cytomegalovirus infection";"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M DNA damage checkpoint"
XP_053990005.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053992814.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053984192.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053986794.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_053979007.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053971596.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053979512.1	2	Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation"
XP_053993589.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_053977181.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053991136.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-400206	"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha"
XP_053979200.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053975179.1	3	Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_053992589.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7254;KEGG: 00620+4.2.1.2	"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Pyruvate metabolism"
XP_053976598.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053976957.1	1	Reactome: R-HSA-211897	"Cytochrome P450 - arranged by substrate type"
XP_053980546.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_053980513.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053985120.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053974864.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053981056.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053976768.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053994308.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053979202.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053980307.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053984203.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053973661.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053976846.1	26	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Gap junction assembly";"Recycling pathway of L1";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_053985122.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053975065.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_053991329.1	8	MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301	"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis"
XP_053985378.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053984874.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053984307.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053971766.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_053972661.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053984190.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053977092.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053975076.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053979334.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_053982199.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053995053.1	2	Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13	"Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system"
XP_053989403.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994931.1	2	Reactome: R-HSA-5673001;Reactome: R-HSA-8853659	"RAF/MAP kinase cascade";"RET signaling"
XP_053976356.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053972824.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053985694.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation"
XP_053988224.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053972451.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053975817.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053990608.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053976291.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053981810.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_053988002.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053978535.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053972361.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053994154.1	1	Reactome: R-HSA-163125	"Post-translational modification: synthesis of GPI-anchored proteins"
XP_053990582.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_053994582.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053983821.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"
XP_053986116.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053994608.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053991955.1	7	Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471	"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053994580.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053984624.1	5	Reactome: R-HSA-381038;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;MetaCyc: PWY-7511	"XBP1(S) activates chaperone genes";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination"
XP_053972398.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053972374.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053983555.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_053984906.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053992995.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_053985066.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053980441.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053970444.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-6783984	"Glyoxylate metabolism and glycine degradation";"Glycine degradation"
XP_053975668.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053986929.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053984441.1	57	Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6"
XP_053983371.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053974444.1	9	KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6351	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053981159.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_053977693.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053988000.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053981812.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053971491.1	40	Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-6781827;Reactome: R-HSA-72203;Reactome: R-HSA-72086	"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping"
XP_053982555.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053981478.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053978434.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_053974031.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053990580.1	3	KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669	"Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I"
XP_053992063.1	2	KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259	"Purine metabolism";"Purine catabolism"
XP_053991492.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053987729.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_053992360.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053992879.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_053991814.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_053983973.1	4	KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755583	"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)"
XP_053980485.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053983776.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053977052.1	6	KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;MetaCyc: PWY-7077;MetaCyc: PWY-6906;Reactome: R-HSA-446210	"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_053989425.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053985354.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_053972142.1	5	KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527	"Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation"
XP_053976696.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053975461.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053980648.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053986098.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_053994669.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_053982776.1	2	Reactome: R-HSA-2408508;Reactome: R-HSA-389661	"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation"
XP_053974046.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053988446.1	2	Reactome: R-HSA-1483115;Reactome: R-HSA-1483152	"Hydrolysis of LPC";"Hydrolysis of LPE"
XP_053974013.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053988413.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053970930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053993879.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053988875.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053987815.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981096.1	3	MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78	"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system"
XP_053981671.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053988638.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_053989507.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_053971674.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_053970428.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053977837.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_053971698.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_053985111.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053976997.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_053987113.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_053973848.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053980238.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053986061.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053975474.1	5	MetaCyc: PWY-5653;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism"
XP_053992883.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053974312.1	4	Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-375165	"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth"
XP_053987592.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053977257.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053980152.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_053994913.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053978388.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053990030.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053990946.1	52	Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-5250924;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-73772	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape"
XP_053979235.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053991573.1	6	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids"
XP_053990237.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_053972104.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_053993883.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053990743.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725	"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053988325.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053977353.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053988248.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053994401.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053989785.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053978942.1	9	Reactome: R-HSA-3656532;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-2173789	"TGFBR1 KD Mutants in Cancer";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs"
XP_053989217.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053989736.1	7	Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;Reactome: R-HSA-446193	"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein"
XP_053970312.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053984238.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053972140.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053983056.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_053984819.1	52	Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768	"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD"
XP_053979521.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_053987489.1	5	Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580	"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence"
XP_053979153.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053973658.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053982169.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053988856.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053972256.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress"
XP_053971609.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053975661.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053975556.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053987057.1	2	Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221	"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis"
XP_053994015.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053973419.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_053983122.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053982147.1	4	MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315	"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_053986264.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053984026.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053978426.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"Neddylation";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053979139.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053980636.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053979445.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053983755.1	10	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053993273.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation"
XP_053984685.1	2	Reactome: R-HSA-164843;Reactome: R-HSA-5693571	"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)"
XP_053972419.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events"
XP_053972065.1	8	Reactome: R-HSA-9609736;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;MetaCyc: PWY-7221	"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis"
XP_053971474.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053988438.1	52	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-6782135;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73779	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"Dual incision in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053974038.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053983169.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053981471.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation"
XP_053973256.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053978979.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_053970628.1	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_053994780.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053984448.1	6	MetaCyc: PWY-6174;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922	"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I"
XP_053978048.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053992804.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_053987250.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053977749.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053988613.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_053988646.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_053979502.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_053992148.1	2	Reactome: R-HSA-2299718;Reactome: R-HSA-2514853	"Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes"
XP_053988920.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053983147.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_053986271.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053976298.1	6	KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_053974386.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_053980937.1	26	Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Gap junction assembly";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053980246.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_053984317.1	1	Reactome: R-HSA-68962	"Activation of the pre-replicative complex"
XP_053989338.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053992965.1	6	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway"
XP_053987252.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053990318.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053979500.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_053978345.1	5	Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21	"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism"
XP_053975698.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053988922.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981795.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053978786.1	4	Reactome: R-HSA-1614558;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;KEGG: 00270+1.13.11.20	"Degradation of cysteine and homocysteine";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Cysteine and methionine metabolism"
XP_053973368.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events"
XP_053994318.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382	"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053988717.1	56	Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21"
XP_053988236.1	17	MetaCyc: PWY-7198;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7210	"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP"
XP_053993289.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053993842.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053971296.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination"
XP_053990782.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050	"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053980317.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053982075.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053984246.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_053981354.1	3	MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928	"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis"
XP_053992827.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053983828.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_053987777.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053984937.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053974915.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_053993965.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315	"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol"
XP_053994601.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053970335.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053981464.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053975409.1	2	KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053992652.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5693554	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053990408.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053983800.1	22	Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558	"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_053972566.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_053991462.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_053972651.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053974602.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053977572.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053978381.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053979721.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053975266.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053973841.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053985812.1	18	MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783	"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation"
XP_053986554.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053983844.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053991773.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053980231.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053994699.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_053992107.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053983108.1	3	MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450	"Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion"
XP_053975491.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053975939.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053987792.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053976375.1	2	Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15	"Synthesis of GDP-mannose";"Starch and sucrose metabolism"
XP_053983654.1	3	Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases"
XP_053979528.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053975055.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053993107.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053981066.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053982844.1	2	KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841	"Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation"
XP_053970602.1	3	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III"
XP_053971668.1	6	KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6606	"Purine metabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II"
XP_053978244.1	4	Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis"
XP_053990206.1	8	Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-182218	"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation"
XP_053986676.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_053987790.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053986091.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-6791226	"Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053980641.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053989707.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053976094.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053976078.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053975468.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053987562.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053975775.1	2	Reactome: R-HSA-6798695;MetaCyc: PWY-7511	"Neutrophil degranulation";"Protein ubiquitination"
XP_053988021.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053986888.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_053970600.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053991789.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053976825.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053983802.1	22	Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-5358747	"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"S33 mutants of beta-catenin aren't phosphorylated"
XP_053992392.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Photosynthesis";"Insulin receptor recycling";"Ion channel transport";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_053971076.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053977493.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053981694.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053988631.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_053989484.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053985810.1	18	KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_053980851.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_053993124.1	179	Reactome: R-HSA-8856825;Reactome: R-HSA-211733;Reactome: R-HSA-209560;Reactome: R-HSA-5689896;Reactome: R-HSA-450302;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-5654726;Reactome: R-HSA-6804756;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-5607761;Reactome: R-HSA-162588;Reactome: R-HSA-5685942;Reactome: R-HSA-168927;Reactome: R-HSA-8856828;Reactome: R-HSA-975144;Reactome: R-HSA-205043;Reactome: R-HSA-2467813;Reactome: R-HSA-2894862;Reactome: R-HSA-936440;Reactome: R-HSA-1234176;Reactome: R-HSA-174178;Reactome: R-HSA-6781823;Reactome: R-HSA-6807004;Reactome: R-HSA-72689;Reactome: R-HSA-69481;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-2871837;Reactome: R-HSA-2173796;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-179409;Reactome: R-HSA-2559580;Reactome: R-HSA-69017;Reactome: R-HSA-3134975;Reactome: R-HSA-5696400;Reactome: R-HSA-5687128;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975110;Reactome: R-HSA-912631;Reactome: R-HSA-4608870;Reactome: R-HSA-3769402;Reactome: R-HSA-937072;Reactome: R-HSA-1358803;Reactome: R-HSA-68949;Reactome: R-HSA-110314;Reactome: R-HSA-2173791;Reactome: R-HSA-5357905;Reactome: R-HSA-9633012;Reactome: R-HSA-2565942;Reactome: R-HSA-975957;Reactome: R-HSA-6782135;Reactome: R-HSA-8875360;Reactome: R-HSA-382556;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-2559585;Reactome: R-HSA-4641257;Reactome: R-HSA-2559582;Reactome: R-HSA-1253288;Reactome: R-HSA-5689603;Reactome: R-HSA-156902;Reactome: R-HSA-4641263;Reactome: R-HSA-5676590;Reactome: R-HSA-9645460;Reactome: R-HSA-9646399;Reactome: R-HSA-8863795;Reactome: R-HSA-5205685;Reactome: R-HSA-9615710;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-5689901;Reactome: R-HSA-1236382;Reactome: R-HSA-5610783;Reactome: R-HSA-9033241;Reactome: R-HSA-8951664;Reactome: R-HSA-6804760;Reactome: R-HSA-187577;Reactome: R-HSA-175474;Reactome: R-HSA-3785653;Reactome: R-HSA-8948747;Reactome: R-HSA-69541;Reactome: R-HSA-180585;Reactome: R-HSA-3322077;Reactome: R-HSA-1295596;Reactome: R-HSA-5689877;Reactome: R-HSA-5675221;Reactome: R-HSA-4641258;Reactome: R-HSA-901032;Reactome: R-HSA-209543;Reactome: R-HSA-9013973;Reactome: R-HSA-69601;Reactome: R-HSA-5655862;Reactome: R-HSA-5632684;Reactome: R-HSA-450321;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-917937;Reactome: R-HSA-6791226;Reactome: R-HSA-5696397;Reactome: R-HSA-174154;Reactome: R-HSA-2173788;Reactome: R-HSA-5693565;Reactome: R-HSA-182971;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-174048;Reactome: R-HSA-5668541;Reactome: R-HSA-5696395;Reactome: R-HSA-201681;Reactome: R-HSA-72706;Reactome: R-HSA-174084;Reactome: R-HSA-532668;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-8941858;Reactome: R-HSA-5357956;Reactome: R-HSA-9604323;Reactome: R-HSA-8866652;Reactome: R-HSA-5693607;Reactome: R-HSA-5684264;Reactome: R-HSA-8852276;Reactome: R-HSA-2122947;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-2979096;Reactome: R-HSA-5675482;Reactome: R-HSA-5654732;Reactome: R-HSA-6804757;Reactome: R-HSA-5654727;Reactome: R-HSA-936964;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-192823;Reactome: R-HSA-9636383;Reactome: R-HSA-2173795;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-72764;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-2122948;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-1799339;Reactome: R-HSA-9637628;Reactome: R-HSA-2691232;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-110312;Reactome: R-HSA-2672351;Reactome: R-HSA-8849469;Reactome: R-HSA-937041;Reactome: R-HSA-5696394;Reactome: R-HSA-9613829;Reactome: R-HSA-6781827;Reactome: R-HSA-2644606;Reactome: R-HSA-168928;Reactome: R-HSA-6783310;Reactome: R-HSA-937039;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-69231;Reactome: R-HSA-5656121;Reactome: R-HSA-1169408;Reactome: R-HSA-8866654;Reactome: R-HSA-8876493	"Cargo recognition for clathrin-mediated endocytosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NF-kB is activated and signals survival";"Ovarian tumor domain proteases";"activated TAK1 mediates p38 MAPK activation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"Negative regulation of FGFR1 signaling";"Regulation of TP53 Activity through Phosphorylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Budding and maturation of HIV virion";"HDR through Homologous Recombination (HRR)";"TICAM1, RIP1-mediated IKK complex recruitment";"Clathrin-mediated endocytosis";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NRIF signals cell death from the nucleus";"Separation of Sister Chromatids";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulators of DDX58/IFIH1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of MET activity";"Formation of a pool of free 40S subunits";"G2/M Checkpoints";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"FCERI mediated NF-kB activation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"APC-Cdc20 mediated degradation of Nek2A";"Oxidative Stress Induced Senescence";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of innate immune responses to cytosolic DNA";"Dual Incision in GG-NER";"MAPK6/MAPK4 signaling";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of signaling by CBL";"Asymmetric localization of PCP proteins";"Deactivation of the beta-catenin transactivating complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Downregulation of ERBB2:ERBB3 signaling";"Orc1 removal from chromatin";"Recognition of DNA damage by PCNA-containing replication complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of TNFR1 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of PLK1 Activity at G2/M Transition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Dual incision in TC-NER";"InlB-mediated entry of Listeria monocytogenes into host cell";"ABC-family proteins mediated transport";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Oncogene Induced Senescence";"Degradation of AXIN";"Senescence-Associated Secretory Phenotype (SASP)";"Downregulation of ERBB4 signaling";"UCH proteinases";"Peptide chain elongation";"Regulation of FZD by ubiquitination";"NIK-->noncanonical NF-kB signaling";"Alpha-protein kinase 1 signaling pathway";"Aggrephagy";"Downregulation of ERBB2 signaling";"Pink/Parkin Mediated Mitophagy";"Late endosomal microautophagy";"Activation of NF-kappaB in B cells";"Circadian Clock";"Metalloprotease DUBs";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Degradation of GLI2 by the proteasome";"Peroxisomal protein import";"Neddylation";"Regulation of TP53 Activity through Methylation";"SCF(Skp2)-mediated degradation of p27/p21";"Assembly Of The HIV Virion";"Myoclonic epilepsy of Lafora";"Regulation of PTEN localization";"Stabilization of p53";"Vif-mediated degradation of APOBEC3G";"Glycogen synthesis";"Spry regulation of FGF signaling";"Josephin domain DUBs";"Negative regulation of MAPK pathway";"Degradation of DVL";"ER Quality Control Compartment (ERQC)";"p75NTR recruits signalling complexes";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by POLK";"Hedgehog 'on' state";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Iron uptake and transport";"Major pathway of rRNA processing in the nucleolus and cytosol";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APC/C:Cdc20 mediated degradation of Securin";"Downregulation of TGF-beta receptor signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"EGFR downregulation";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"TNFR2 non-canonical NF-kB pathway";"Formation of Incision Complex in GG-NER";"TCF dependent signaling in response to WNT";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Autodegradation of Cdh1 by Cdh1:APC/C";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of RUNX3 expression and activity";"TNFR1-induced NFkappaB signaling pathway";"Negative regulation of NOTCH4 signaling";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Processing of DNA double-strand break ends";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NOTCH1 Intracellular Domain Regulates Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of necroptotic cell death";"Negative regulation of FGFR3 signaling";"Regulation of TP53 Degradation";"Negative regulation of FGFR2 signaling";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Viral mRNA Translation";"Prevention of phagosomal-lysosomal fusion";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"Eukaryotic Translation Termination";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"SRP-dependent cotranslational protein targeting to membrane";"Modulation by Mtb of host immune system";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Translesion synthesis by REV1";"Stimuli-sensing channels";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IKK complex recruitment mediated by RIP1";"DNA Damage Recognition in GG-NER";"Chaperone Mediated Autophagy";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fanconi Anemia Pathway";"IRAK1 recruits IKK complex";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Cyclin D associated events in G1";"Translesion synthesis by POLI";"ISG15 antiviral mechanism";"E3 ubiquitin ligases ubiquitinate target proteins";"InlA-mediated entry of Listeria monocytogenes into host cells"
XP_053974644.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053981835.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053978895.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)"
XP_053982416.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053982443.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053990294.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053974639.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_053986608.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_053970880.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053978667.1	14	KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;Reactome: R-HSA-75109;MetaCyc: PWY-8052	"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis"
XP_053989450.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053986582.1	4	Reactome: R-HSA-2408557;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Selenocysteine synthesis";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_053983259.1	4	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053988976.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053987868.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053980070.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053988352.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984277.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-69473	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint"
XP_053982682.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_053979089.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_053993012.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053974062.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053973704.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053986311.1	5	Reactome: R-HSA-168638;Reactome: R-HSA-171007;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-376172	"NOD1/2 Signaling Pathway";"p38MAPK events";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"DSCAM interactions"
XP_053975902.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053972623.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053972910.1	5	MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821	"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose detoxification"
XP_053980125.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_053972166.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053983443.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053987385.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053983416.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053979753.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_053979956.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053987336.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796	"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation"
XP_053981606.1	10	KEGG: 05163+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Ub-specific processing proteases";"Human papillomavirus infection";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HATs acetylate histones";"Thermogenesis"
XP_053978470.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053983682.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053984752.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053973330.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053986154.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053981924.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_053994294.1	5	MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_053971921.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053989136.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053974029.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053992507.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"Rho GTPase cycle";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_053994278.1	1	Reactome: R-HSA-203641	"NOSTRIN mediated eNOS trafficking"
XP_053983508.1	4	Reactome: R-HSA-9020702;Reactome: R-HSA-975144;Reactome: R-HSA-937039;MetaCyc: PWY-7511	"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Protein ubiquitination"
XP_053993217.1	5	MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-7863	"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis"
XP_053974267.1	13	KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-202433;Reactome: R-HSA-1855204;Reactome: R-HSA-2424491;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2029485;MetaCyc: PWY-6367;Reactome: R-HSA-9027277;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;MetaCyc: PWY-6351	"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Generation of second messenger molecules";"Synthesis of IP3 and IP4 in the cytosol";"DAP12 signaling";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053970363.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053994655.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053972912.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053994929.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053977686.1	10	Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942	"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition"
XP_053982839.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids"
XP_053970453.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053971305.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053979073.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_053983680.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053980823.1	13	Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-2214320;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Laminin interactions";"ECM proteoglycans";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Collagen chain trimerization";"NCAM1 interactions";"Anchoring fibril formation";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_053984750.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_053992346.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_053983176.1	8	Reactome: R-HSA-73614;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-7199	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage"
XP_053985406.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053978110.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053989452.1	6	KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_053970882.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053980750.1	3	Reactome: R-HSA-1810476;Reactome: R-HSA-933542;Reactome: R-HSA-445989	"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex"
XP_053975714.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053985711.1	7	Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_053992933.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_053975944.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053992785.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-1268020	"Oxidative phosphorylation";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"ATP biosynthesis";"Mitochondrial protein import"
XP_053979822.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053980072.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053988350.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053972727.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053990929.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053988053.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053979657.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_053992524.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-194840;Reactome: R-HSA-1257604;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-8853659	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"Regulation of signaling by CBL";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Rho GTPase cycle";"PIP3 activates AKT signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"RET signaling"
XP_053975900.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053993346.1	1	Reactome: R-HSA-211981	"Xenobiotics"
XP_053971047.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053984103.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_053975387.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053975928.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053981380.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053988692.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-5826;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13	"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Hypoglycin biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione metabolism"
XP_053983569.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276	"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_053986622.1	14	Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128	"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling"
XP_053973605.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692	"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity"
XP_053974961.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053993911.1	1	Reactome: R-HSA-391908	"Prostanoid ligand receptors"
XP_053975001.1	13	KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2160916	"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation"
XP_053971069.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5689880;Reactome: R-HSA-111465	"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins"
XP_053985004.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_053981437.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053986857.1	9	Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385	"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)"
XP_053975430.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053978497.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053984097.1	11	Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-72163;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606	"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053991646.1	17	Reactome: R-HSA-167287;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167290;KEGG: 04658+3.1.3.16;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Th1 and Th2 cell differentiation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_053982569.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053995173.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053970961.1	3	KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695	"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation"
XP_053975156.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism"
XP_053976442.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053981165.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053994098.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053972605.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_053971240.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053980103.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053985733.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053981079.1	32	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-73779	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053986401.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis"
XP_053974974.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053991922.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053981863.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_053977281.1	11	Reactome: R-HSA-3560783;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3000170;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-975634	"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Syndecan interactions";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport"
XP_053982014.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053985027.1	7	MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8	"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism"
XP_053982306.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053973579.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053976679.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053990395.1	3	MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17	"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis"
XP_053971175.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053992684.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053989141.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053981382.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053985220.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053979144.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-180585	"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G"
XP_053986620.1	14	Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes"
XP_053991236.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_053986237.1	15	Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896	"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases"
XP_053986946.1	12	KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1839117	"Thermogenesis";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"mTOR signaling pathway";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants"
XP_053984805.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053970974.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_053970557.1	5	Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757	"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation"
XP_053975432.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053995028.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053981042.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_053994009.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053989093.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053991901.1	5	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_053987307.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053994990.1	15	Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418	"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex"
XP_053991189.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053981637.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053992724.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053978697.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053977084.1	1	Reactome: R-HSA-2024096	"HS-GAG degradation"
XP_053972214.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_053987081.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053986780.1	5	Reactome: R-HSA-211981;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-8937144	"Xenobiotics";"Endogenous sterols";"PPARA activates gene expression";"Phase I - Functionalization of compounds";"Aryl hydrocarbon receptor signalling"
XP_053971279.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053992585.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053985863.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053972196.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053993724.1	6	Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-5685939;Reactome: R-HSA-69166	"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate"
XP_053978563.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_053972542.1	3	Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427	"Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains"
XP_053991413.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053988589.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053983211.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053985718.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053975889.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053973214.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053977905.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053976640.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053982501.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053984552.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_053970393.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053976926.1	26	Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly"
XP_053975204.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053985201.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053979553.1	11	Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-418555	"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events"
XP_053989124.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_053979121.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053981040.1	14	KEGG: 00562+3.1.4.11;Reactome: R-HSA-434316;Reactome: R-HSA-418217;Reactome: R-HSA-399997;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351	"Inositol phosphate metabolism";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G beta:gamma signalling through PLC beta";"Acetylcholine regulates insulin secretion";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053987546.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053982708.1	4	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053981316.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053975047.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053983501.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053985380.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053973504.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053971387.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_053975632.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053991248.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_053976232.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053975415.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053975069.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053975873.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053984184.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053988573.1	12	Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy"
XP_053986516.1	52	Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884	"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis"
XP_053983853.1	2	Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053979975.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053992625.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053994182.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053983599.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053981941.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053982616.1	7	MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;MetaCyc: PWY-7625	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_053971099.1	3	Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_053974991.1	9	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint"
XP_053993035.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_053991224.1	56	Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_053987982.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053983482.1	33	Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159227	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA"
XP_053987177.1	1	KEGG: 00270+2.1.1.37	"Cysteine and methionine metabolism"
XP_053988955.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053970991.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053973779.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053987225.1	3	KEGG: 00480+4.3.2.9;Reactome: R-HSA-174403;MetaCyc: PWY-4041	"Glutathione metabolism";"Glutathione synthesis and recycling";"Gamma-glutamyl cycle"
XP_053986699.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053981195.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053987531.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187	"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress"
XP_053983616.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053989148.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053988117.1	10	Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-2514853;Reactome: R-HSA-445144	"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"WNT mediated activation of DVL";"Synthesis of PC";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1"
XP_053978670.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053981406.1	10	KEGG: 04150+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153	"mTOR signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053984262.1	18	Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-72086	"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"mRNA Capping"
XP_053983480.1	33	Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159236	"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053987045.1	7	KEGG: 00230+2.4.2.14;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-7282;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277	"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_053978833.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053972783.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053970270.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053985606.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1"
XP_053972935.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053992541.1	16	Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-1433557;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-1266695	"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Interleukin receptor SHC signaling";"RET signaling";"Signaling by SCF-KIT";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"Rho GTPase cycle";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin-7 signaling"
XP_053974077.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053987417.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964	"IKK complex recruitment mediated by RIP1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon"
XP_053973059.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053990676.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_053986206.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053992338.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053980229.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053976705.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053975921.1	6	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape"
XP_053979263.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053985924.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053994091.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053970843.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053973935.1	9	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053973986.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053974653.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053994180.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053983747.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053982480.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053991303.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053983917.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053992918.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053989827.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Oxidative phosphorylation"
XP_053972315.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979349.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053972059.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053985287.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053993602.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053985945.1	6	Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-5685939	"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)"
XP_053986779.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053971280.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053977908.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_053991412.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_053991894.1	12	Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-5250924	"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression"
XP_053992234.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053975243.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053979550.1	11	Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040	"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053970390.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053976720.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_053987024.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053986687.1	11	Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-68952;Reactome: R-HSA-174430	"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"DNA replication initiation";"Telomere C-strand synthesis initiation"
XP_053978562.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053973699.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053986018.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053993234.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_053975870.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053981304.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981877.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053992588.1	16	Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-1266695;Reactome: R-HSA-388841;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557	"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Rho GTPase cycle";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin-7 signaling";"Costimulation by the CD28 family";"Interleukin receptor SHC signaling";"RET signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT"
XP_053975459.1	1	Reactome: R-HSA-163765	"ChREBP activates metabolic gene expression"
XP_053988570.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_053990841.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_053994566.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053981340.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053987895.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_053972699.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_053989092.1	11	KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6549;Reactome: R-HSA-8964539;MetaCyc: PWY-381;MetaCyc: PWY-6963;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2	"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"L-glutamine biosynthesis III";"Glutamate and glutamine metabolism";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle I";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Arginine biosynthesis"
XP_053987510.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053981043.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_053985080.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053987381.1	2	Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053976747.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Gap junction assembly";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053976233.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053991987.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053980121.1	10	MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)"
XP_053988572.1	12	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy"
XP_053991328.1	18	Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_053986986.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053986783.1	20	MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6	"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism"
XP_053986935.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053975633.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053994796.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053971659.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053975506.1	6	Reactome: R-HSA-139915;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803204	"Activation of PUMA and translocation to mitochondria";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_053981327.1	14	Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-110314	"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Polymerase switching";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053992854.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053981988.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis"
XP_053975320.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_053979552.1	11	Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660	"G alpha (z) signalling events";"G alpha (s) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway"
XP_053990309.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053970392.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053983705.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_053986315.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053985860.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885	"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins"
XP_053973206.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053978560.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053989145.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053986527.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"Cilium Assembly";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_053981174.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053994065.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813	"SUMOylation of DNA damage response and repair proteins";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Estrogen-dependent gene expression";"Separation of Sister Chromatids"
XP_053994419.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_053971171.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053985614.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053970650.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_053975308.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053978830.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_053981515.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_053986214.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053976211.1	1	Reactome: R-HSA-1614558	"Degradation of cysteine and homocysteine"
XP_053982230.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053982627.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053985530.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-3000471;Reactome: R-HSA-8964026	"Platelet sensitization by LDL";"LDL clearance";"Chylomicron assembly";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL remodeling";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL assembly";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Scavenging by Class B Receptors";"Chylomicron clearance"
XP_053991281.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053988597.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053978252.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053989757.1	6	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_053971537.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053988958.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053973447.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_053972015.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation"
XP_053970377.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053986196.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053977717.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922	"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_053977236.1	7	KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4;Reactome: R-HSA-77111;Reactome: R-HSA-9033241	"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Butanoate metabolism";"Synthesis of Ketone Bodies";"Peroxisomal protein import"
XP_053979049.1	2	Reactome: R-HSA-5601884;Reactome: R-HSA-1221632	"PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis"
XP_053987983.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-983168	"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984975.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053983119.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053991344.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053994183.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053974650.1	4	Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546;Reactome: R-HSA-982772	"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling";"Growth hormone receptor signaling"
XP_053994391.1	2	Reactome: R-HSA-72764;Reactome: R-HSA-156581	"Eukaryotic Translation Termination";"Methylation"
XP_053972447.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053973780.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053990419.1	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-2301	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phytate degradation I";"Myo-inositol biosynthesis"
XP_053991003.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053979978.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972	"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053978777.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053991300.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053983230.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053992628.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053984457.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_053993386.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981205.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053993335.1	12	KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5871	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_053988339.1	8	Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-191273	"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis"
XP_053984367.1	52	Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-203927;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-6803529;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-72203;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"MicroRNA (miRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_053985981.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-532668;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_053974652.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231;Reactome: R-HSA-2586552	"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin"
XP_053973782.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_053970842.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053982604.1	12	MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484	"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)"
XP_053987426.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053973938.1	27	Reactome: R-HSA-5358752;Reactome: R-HSA-5610783;Reactome: R-HSA-399956;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5467348;Reactome: R-HSA-8939902;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-75815;Reactome: R-HSA-196299;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5358751;KEGG: 04151+2.7.11.1;Reactome: R-HSA-195253;Reactome: R-HSA-5467340;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-5358747;Reactome: R-HSA-5250924;Reactome: R-HSA-5467337	"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of GLI2 by the proteasome";"CRMPs in Sema3A signaling";"Human immunodeficiency virus 1 infection";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"mTOR signaling pathway";"GLI3 is processed to GLI3R by the proteasome";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"Truncations of AMER1 destabilize the destruction complex";"Regulation of RUNX2 expression and activity";"Thermogenesis";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"Ubiquitin-dependent degradation of Cyclin D";"Beta-catenin phosphorylation cascade";"Human papillomavirus infection";"S45 mutants of beta-catenin aren't phosphorylated";"PI3K-Akt signaling pathway";"Degradation of beta-catenin by the destruction complex";"AXIN missense mutants destabilize the destruction complex";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"S33 mutants of beta-catenin aren't phosphorylated";"B-WICH complex positively regulates rRNA expression";"APC truncation mutants have impaired AXIN binding"
XP_053991302.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053984349.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053985109.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983479.1	33	Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-170822	"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_053987979.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053976708.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053977438.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053993157.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053972420.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_053979262.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053992386.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053983926.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053974289.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_053972938.1	6	Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_053980367.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053982232.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_053984263.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053989816.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053981892.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_053994179.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053993745.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053978250.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053988749.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053980457.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053972782.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053987048.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-7282;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14	"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism"
XP_053990142.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053980820.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885	"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins"
XP_053983505.1	27	Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-112382;Reactome: R-HSA-159236;Reactome: R-HSA-167200;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-191859;Reactome: R-HSA-77588;Reactome: R-HSA-6807505;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-9010553;Reactome: R-HSA-167158;Reactome: R-HSA-77595;Reactome: R-HSA-975956;Reactome: R-HSA-159227	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"Formation of RNA Pol II elongation complex";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"snRNP Assembly";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Regulation of expression of SLITs and ROBOs";"Formation of the HIV-1 Early Elongation Complex";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Transport of the SLBP independent Mature mRNA"
XP_053983683.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053982427.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053979070.1	24	Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-190840	"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Recycling pathway of L1";"Gap junction assembly";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_053976522.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053978146.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_053980089.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053978760.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053991864.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_053972622.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-156711	"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events"
XP_053973669.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053994619.1	7	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_053991321.1	18	Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053970450.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053979752.1	1	Reactome: R-HSA-901032	"ER Quality Control Compartment (ERQC)"
XP_053989880.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053975411.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664	"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation"
XP_053983442.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053988050.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053974450.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053987712.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053988353.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053975399.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053972647.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053975903.1	8	KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1	"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_053992428.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053993013.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053975706.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053983427.1	4	KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202	"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines"
XP_053989639.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053993046.1	2	Reactome: R-HSA-5576894;Reactome: R-HSA-1296072	"Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels"
XP_053978489.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053976547.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_053987865.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053982442.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053985161.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053980956.1	5	MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667	"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I"
XP_053992930.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053988052.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053974452.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053991084.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_053980073.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053987626.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053982404.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053987710.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979823.1	3	Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901	"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling"
XP_053972401.1	4	Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-1655829;Reactome: R-HSA-381033	"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones"
XP_053993226.1	25	Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690	"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Recycling pathway of L1";"Gap junction assembly";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events"
XP_053994104.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053979389.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053977028.1	3	Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-159230	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA"
XP_053983679.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053983215.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_053977901.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053983787.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_053976799.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053993581.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex"
XP_053991871.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_053973743.1	9	Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475;Reactome: R-HSA-975634;Reactome: R-HSA-2024096	"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis";"Retinoid metabolism and transport";"HS-GAG degradation"
XP_053989453.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis"
XP_053970883.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053973237.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_053992312.1	5	KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-193048;Reactome: R-HSA-4755579	"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ"
XP_053980822.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053977413.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053976520.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053979072.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins"
XP_053981614.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053985198.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053971611.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053984847.1	11	MetaCyc: PWY-5695;MetaCyc: PWY-7185;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7821;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5	"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I";"Adenosine nucleotides degradation I";"Purine metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation I";"Pyrimidine metabolism"
XP_053973401.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053980657.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053978762.1	1	Reactome: R-HSA-8849175	"Threonine catabolism"
XP_053974329.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053983404.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053972946.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053993932.1	2	Reactome: R-HSA-1362409;Reactome: R-HSA-1268020	"Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import"
XP_053972913.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053972620.1	7	Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-156711	"G1/S-Specific Transcription";"G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events"
XP_053972716.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053972237.1	24	Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-392170	"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12"
XP_053985515.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053971897.1	5	MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"D-galactose detoxification";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_053972743.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053978590.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053984073.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053994658.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053989882.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053979750.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053970452.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053983440.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053977207.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053985732.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053988549.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_053991435.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_053994095.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053991486.1	2	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)"
XP_053981379.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053975867.1	2	KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_053973154.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-6147;MetaCyc: PWY-6703;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7442	"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis"
XP_053986330.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053990824.1	19	Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-182971;Reactome: R-HSA-3928662;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"EGFR downregulation";"EPHB-mediated forward signaling";"Myogenesis";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"Rho GTPase cycle";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_053988567.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_053986910.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053983006.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053991167.1	29	Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_053971872.1	5	Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053986740.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053986623.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723	"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation"
XP_053972499.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053973608.1	16	Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling"
XP_053980539.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-983231	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production"
XP_053975925.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053985342.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_053986704.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053976701.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053983314.1	6	KEGG: 00270+2.6.1.52;KEGG: 00750+2.6.1.52;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00260+2.6.1.52;Reactome: R-HSA-977347	"Cysteine and methionine metabolism";"Vitamin B6 metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_053988693.1	10	KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-7112	"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification"
XP_053975659.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053977000.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_053985304.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053971870.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_053986742.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053992444.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_053975433.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053978577.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053984808.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053985016.1	4	Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946	"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin"
XP_053977517.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053981829.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053990807.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
XP_053975087.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053981191.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053981383.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053975618.1	3	Reactome: R-HSA-4608870;Reactome: R-HSA-2173791;Reactome: R-HSA-420029	"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Tight junction interactions"
XP_053978131.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-201722;Reactome: R-HSA-2173796;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"Formation of the beta-catenin:TCF transactivating complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_053981080.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053981945.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053994398.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-1268020	"Cristae formation";"Mitochondrial protein import"
XP_053994807.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053985730.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053979971.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053971737.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053991923.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_053981862.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_053984293.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053991726.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_053991610.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053973182.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813	"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids"
XP_053977477.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053976654.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_053986651.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_053990687.1	6	Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-9640463;Reactome: R-HSA-75105	"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"Wax biosynthesis";"Fatty acyl-CoA biosynthesis"
XP_053978045.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053984445.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053980139.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053985709.1	7	Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178	"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans"
XP_053979503.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053988612.1	6	Reactome: R-HSA-5632928;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5632968	"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Defective Mismatch Repair Associated With MSH6"
XP_053990779.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_053993272.1	8	Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_053974035.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053984502.1	4	Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724	"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription"
XP_053982551.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053992757.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_053985251.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_053972068.1	8	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053970959.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_053971051.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053984210.1	29	Reactome: R-HSA-3371453;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696395;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-110314;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-3108214;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616	"Regulation of HSF1-mediated heat shock response";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Recognition of DNA damage by PCNA-containing replication complex";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"SUMOylation of DNA damage response and repair proteins";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053981054.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053974625.1	6	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053976800.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981568.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053978980.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053976108.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053984139.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;MetaCyc: PWY-7921;Reactome: R-HSA-5173105	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation I (yeast)";"O-linked glycosylation"
XP_053994018.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053992991.1	6	Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_053992439.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053988167.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-6794361;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066	"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"EPHB-mediated forward signaling";"Long-term potentiation";"Neurexins and neuroligins";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_053983123.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053983666.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053982967.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053991134.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-1989781	"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"PPARA activates gene expression"
XP_053992653.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568	"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053989157.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053993077.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053989745.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053973455.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053974866.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053979213.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP"
XP_053971771.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_053973365.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_053994315.1	6	Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053994986.1	4	KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053977629.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053983967.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053989335.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053973676.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053978177.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_053992843.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_053987670.1	12	MetaCyc: PWY-6613;KEGG: 00230+2.1.2.2;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6121;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;MetaCyc: PWY-6122;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+6.3.3.1;KEGG: 00670+2.1.2.9;KEGG: 00670+2.1.2.2	"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"One carbon pool by folate";"One carbon pool by folate"
XP_053975834.1	14	Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-6811436	"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053993270.1	8	Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Macroautophagy"
XP_053984500.1	4	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_053992816.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053980326.1	10	MetaCyc: PWY-6397;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-7328;Reactome: R-HSA-70370	"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism"
XP_053971578.1	6	MetaCyc: PWY-5653;MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism"
XP_053973888.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_053974338.1	5	MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891	"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)"
XP_053976295.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_053988321.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;MetaCyc: PWY-6174;Reactome: R-HSA-2426168	"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Activation of gene expression by SREBF (SREBP)"
XP_053994405.1	2	Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22	"Fatty acyl-CoA biosynthesis";"Fatty acid elongation"
XP_053970536.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_053976755.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053973990.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053970585.1	6	Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368	"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_053976147.1	2	Reactome: R-HSA-1566948;Reactome: R-HSA-2243919	"Elastic fibre formation";"Crosslinking of collagen fibrils"
XP_053987793.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053975058.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053987996.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053986391.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053980721.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053989588.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_053983105.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_053986419.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway"
XP_053985846.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053983496.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053972009.1	5	Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex"
XP_053974603.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053980528.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053979407.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_053982298.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8951664	"Neutrophil degranulation";"Neddylation"
XP_053993297.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053987697.1	14	MetaCyc: PWY-3781;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-71403;Reactome: R-HSA-611105;MetaCyc: PWY-6728	"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Methylaspartate cycle"
XP_053978898.1	11	Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565	"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants"
XP_053975571.1	1	Reactome: R-HSA-5683826	"Surfactant metabolism"
XP_053977492.1	6	Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-912446;Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-6796648	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination";"Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053986179.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053981675.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053988084.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053989644.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053970707.1	40	Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167243;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-72163;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-167242	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated HIV elongation arrest and recovery";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"mRNA Splicing - Major Pathway";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_053981366.1	4	Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053974707.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053989854.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053986836.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_053975794.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053981456.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053983298.1	7	MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824	"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis"
XP_053973271.1	3	KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386	"Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I"
XP_053973992.1	1	KEGG: 00906+1.23.5.1	"Carotenoid biosynthesis"
XP_053971826.1	9	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway"
XP_053975465.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053993090.1	29	Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_053986596.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_053988281.1	2	KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053984700.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053991958.1	7	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-5620922	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium"
XP_053988734.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_053971778.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053984744.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_053982696.1	2	Reactome: R-HSA-168276;Reactome: R-HSA-1169408	"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism"
XP_053994605.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053994583.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053982071.1	20	Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5656169	"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis"
XP_053976973.1	7	KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;Reactome: R-HSA-69205;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_053990583.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_053975950.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053983884.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-437239	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Recycling pathway of L1"
XP_053970741.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053981957.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053978538.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053984334.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053980744.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053985219.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053986619.1	14	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity"
XP_053988197.1	5	KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;MetaCyc: PWY-4983	"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)"
XP_053989402.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053981813.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053977692.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053982558.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053972061.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053986658.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053987497.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053975376.1	13	MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913	"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)"
XP_053979034.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053994579.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053991339.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-174411	"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Polymerase switching";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere"
XP_053980702.1	6	Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_053990579.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053984702.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_053983064.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053975665.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053989621.1	17	Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-179409;Reactome: R-HSA-174178	"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1"
XP_053978809.1	2	Reactome: R-HSA-9033500;Reactome: R-HSA-9033241	"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import"
XP_053971058.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_053970684.1	12	Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1	"G alpha (q) signalling events";"Thermogenesis";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"DCC mediated attractive signaling";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"NRAGE signals death through JNK";"Relaxin signaling pathway"
XP_053979906.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053988635.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_053983187.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_053989046.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_053992188.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-2160916	"AURKA Activation by TPX2";"Hyaluronan uptake and degradation"
XP_053989013.1	1	Reactome: R-HSA-4419969	"Depolymerisation of the Nuclear Lamina"
XP_053976199.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053970425.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053977789.1	56	Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577	"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21"
XP_053994910.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176	"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_053988170.1	9	Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-442982	"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"EPHB-mediated forward signaling";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053986824.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053978617.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053988894.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053987763.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053981831.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053992880.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053979436.1	5	KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_053974012.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053994704.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053980855.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053984855.1	7	MetaCyc: PWY-7154;Reactome: R-HSA-191273;Reactome: R-HSA-9022692;KEGG: 00100+1.3.1.70;MetaCyc: PWY-6074;MetaCyc: PWY-8026;MetaCyc: PWY-2541	"Ergosterol biosynthesis II";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity";"Steroid biosynthesis";"Zymosterol biosynthesis";"Sterol biosynthesis (methylotrophs)";"Phytosterol biosynthesis (plants)"
XP_053972960.1	2	Reactome: R-HSA-174403;Reactome: R-HSA-5578999	"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_053972143.1	5	MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22	"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Sphingolipid metabolism";"Glycerolipid metabolism"
XP_053983356.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_053994487.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053979150.1	9	KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00270+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00350+2.6.1.5	"Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Cysteine and methionine metabolism";"Tyrosine catabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism"
XP_053990740.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053991493.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053992062.1	2	KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259	"Purine metabolism";"Purine catabolism"
XP_053977460.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053977053.1	6	MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7077;Reactome: R-HSA-446210	"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine"
XP_053993029.1	14	MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725	"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053988025.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_053974425.1	4	KEGG: 00030+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268	"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053983972.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053977350.1	1	Reactome: R-HSA-5635838	"Activation of SMO"
XP_053975051.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053987667.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053973655.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_053974217.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053982268.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053979152.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053980728.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053985568.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053984286.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053990742.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053988328.1	8	Reactome: R-HSA-2426168;MetaCyc: PWY-6174;Reactome: R-HSA-191273;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34	"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis"
XP_053984521.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_053993882.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053972845.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-9033241	"Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import"
XP_053984153.1	7	MetaCyc: PWY-7221;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;MetaCyc: PWY-6596;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817	"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Purine metabolism";"Adenosine nucleotides degradation I";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis"
XP_053978943.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053978160.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053983970.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053977352.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053978385.1	4	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_053994912.1	57	Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276	"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_053989226.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053980286.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-167243	"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Neddylation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_053984728.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053980235.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053989581.1	6	MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64+3.1.3.95;KEGG: 00562+3.1.3.64+3.1.3.95;Reactome: R-HSA-1660499;MetaCyc: PWY-6580;MetaCyc: PWY-6367	"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"D-myo-inositol-5-phosphate metabolism"
XP_053992882.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053974313.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_053974346.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053970736.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053970933.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053971254.1	4	KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion"
XP_053974010.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053981251.1	4	MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895	"2,4-dinitrotoluene degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_053982405.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053988563.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_053975079.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053974550.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053983214.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053987905.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053975718.1	4	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK"
XP_053994261.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053985242.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053975948.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053977203.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053978589.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053985227.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053987871.1	1	Reactome: R-HSA-1483166	"Synthesis of PA"
XP_053975382.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053977307.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053971220.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053981615.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053979390.1	3	Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053976422.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053979093.1	1	Reactome: R-HSA-6783984	"Glycine degradation"
XP_053971042.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053983405.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053978492.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053981432.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053990105.1	7	Reactome: R-HSA-381070;Reactome: R-HSA-381033;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-983170	"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_053975511.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053972211.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_053977081.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_053987084.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053990496.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053991710.1	29	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782210	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053986627.1	14	Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723	"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation"
XP_053975083.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053994298.1	10	MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1;KEGG: 00051+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00010+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_053994274.1	12	Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862	"Notch-HLH transcription pathway";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053983504.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053985047.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053971343.1	7	Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription"
XP_053986158.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053978490.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053975437.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053983540.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_053976782.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_053984181.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053981430.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053981001.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis"
XP_053985069.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053991712.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Dual incision in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_053975201.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053971269.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053973708.1	4	Reactome: R-HSA-212300;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"PRC2 methylates histones and DNA";"DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_053995048.1	7	Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-379716;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315	"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol"
XP_053981156.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053991388.1	3	MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048	"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG"
XP_053986926.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053984297.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053974552.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053989121.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053985240.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053975759.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053979124.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053971985.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053988996.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053985022.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_053982540.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_053970978.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_053977348.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053985305.1	3	Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603	"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine"
XP_053995024.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_053980272.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053984145.1	3	Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism"
XP_053972853.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_053990758.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053979840.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053973482.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_053992876.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053993210.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053992502.1	7	MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_053978117.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053988670.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053994123.1	13	Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485	"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis"
XP_053988186.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053971195.1	5	MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26;Reactome: R-HSA-9033241;Reactome: R-HSA-75896;Reactome: R-HSA-9033500	"Plasmalogen biosynthesis";"Ether lipid metabolism";"Peroxisomal protein import";"Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins"
XP_053984757.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053976699.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053992017.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053988449.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_053981944.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053993876.1	3	Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_053980757.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053990666.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053989975.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053987288.1	20	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053988467.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053982687.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053993688.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053978039.1	8	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"mTOR signaling pathway"
XP_053980145.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053984272.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053972720.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053972643.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053973747.1	3	KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286	"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation"
XP_053989457.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053978660.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053995007.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053974229.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053983783.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974	"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway"
XP_053983935.1	3	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism"
XP_053994949.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_053973155.1	9	MetaCyc: PWY-6983;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-5664;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6703	"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Preq0 biosynthesis"
XP_053982315.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_053972722.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053979827.1	6	KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817	"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_053978477.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053982986.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053984077.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053971559.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982783.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_053980270.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_053984968.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053979842.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053990719.1	10	KEGG: 00710+2.2.1.1;MetaCyc: PWY-6901;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;MetaCyc: PWY-1861;MetaCyc: PWY-5723;MetaCyc: PWY-6892;KEGG: 00030+2.2.1.1	"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Methylerythritol phosphate pathway II";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Pentose phosphate pathway"
XP_053987612.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_053984816.1	52	Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761	"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling"
XP_053989263.1	11	Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579	"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange"
XP_053992500.1	7	KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61	"Tryptophan metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_053985921.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053972155.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_053986705.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053980653.1	7	KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-7255	"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)"
XP_053976206.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053977417.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053974070.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300	"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_053988593.1	5	KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109	"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis"
XP_053984188.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053973416.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053989753.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825	"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis"
XP_053971533.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982166.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053980062.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981008.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events"
XP_053982910.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053987172.1	10	Reactome: R-HSA-5689880;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-917729;Reactome: R-HSA-432720	"Ub-specific processing proteases";"Negative regulation of MET activity";"Inhibition of membrane repair";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis"
XP_053983487.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053986934.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053979185.1	6	Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"mRNA Splicing - Major Pathway";"snRNP Assembly";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_053988112.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_053984029.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053978429.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_053980639.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053979136.1	10	MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-5609977	"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)"
XP_053986151.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053989372.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053974752.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053991200.1	12	MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-2821;MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-601;MetaCyc: PWY-6309;MetaCyc: PWY-6936;Reactome: R-HSA-71240	"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Tryptophan metabolism";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from phenylalanine";"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tryptophan";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Tryptophan catabolism"
XP_053973682.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053983033.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_053987410.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase"
XP_053992855.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053978773.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053983166.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053983740.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053973259.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053982487.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"UCH proteinases"
XP_053983623.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053989128.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases"
XP_053972443.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053980029.1	14	KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-6728;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1	"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes"
XP_053984062.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053986314.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053972682.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053973701.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_053977943.1	7	MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7176	"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Drug metabolism - other enzymes";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis"
XP_053970373.1	3	Reactome: R-HSA-4419969;Reactome: R-HSA-2995383;Reactome: R-HSA-2980766	"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation";"Nuclear Envelope Breakdown"
XP_053972508.1	2	KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710	"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053975941.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053983912.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053985944.1	6	Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-5685939	"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)"
XP_053973218.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053985714.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053980249.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_053992235.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053991510.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053979362.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053984363.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053992521.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053982332.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_053984060.1	34	Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159227;Reactome: R-HSA-9639288;Reactome: R-HSA-170822	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of the SLBP independent Mature mRNA";"Amino acids regulate mTORC1";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_053989657.1	17	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053978053.1	1	Reactome: R-HSA-1655829	"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_053985099.1	4	Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23	"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism"
XP_053993728.1	57	Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176	"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"
XP_053978350.1	7	Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053993286.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053979329.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_053980363.1	2	Reactome: R-HSA-5578998;Reactome: R-HSA-174403	"Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling"
XP_053972218.1	5	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_053988966.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_053970389.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053987894.1	4	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053988110.1	5	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_053988763.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_053973176.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053984882.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053993521.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity"
XP_053989370.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053973680.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053987412.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5626467	"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs"
XP_053993153.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053980961.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053991048.1	12	Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-6309;MetaCyc: PWY-601;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187	"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine"
XP_053993334.1	6	MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;Reactome: R-HSA-70221	"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)"
XP_053975269.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053973522.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053974290.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_053972569.1	4	KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)"
XP_053975733.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053981240.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053975936.1	26	Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-190840	"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_053991979.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053994071.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053971165.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053978692.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_053975222.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053973569.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_053987302.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981632.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053971083.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053975040.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_053993700.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053972522.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053975316.1	4	Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-8953750	"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcriptional Regulation by E2F6"
XP_053985430.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053970290.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053973547.1	3	Reactome: R-HSA-2151201;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Transcriptional activation of mitochondrial biogenesis";"UCH proteinases";"HATs acetylate histones"
XP_053985001.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053981873.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053994558.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_053975637.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053978690.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_053989144.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053987003.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053981630.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053987300.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981175.1	17	Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167290;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_053983011.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053975042.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053994064.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214	"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins"
XP_053993702.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053992681.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_053972520.1	6	KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation"
XP_053989100.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_053986215.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053971511.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053985432.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053991983.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053970292.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_053991786.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053973799.1	1	Reactome: R-HSA-2468052	"Establishment of Sister Chromatid Cohesion"
XP_053976913.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053995163.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053976743.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053976716.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_053992702.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6804756	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation"
XP_053982011.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053976030.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053973520.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion"
XP_053995085.1	23	Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-456926;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-418597	"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"G alpha (z) signalling events"
XP_053974292.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_053991345.1	2	Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053971079.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053981242.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053983579.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-5205685	"Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy"
XP_053971718.1	7	Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-69205	"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription"
XP_053972306.1	7	KEGG: 00565+3.1.4.4;MetaCyc: PWY-3561;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148	"Ether lipid metabolism";"Choline biosynthesis III";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"Synthesis of PA";"Glycerophospholipid metabolism";"Synthesis of PG"
XP_053975027.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053980628.1	17	MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5695;MetaCyc: PWY-6620;MetaCyc: PWY-6644;Reactome: R-HSA-74259;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6627	"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis"
XP_053988979.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053990483.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053971471.1	10	KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;MetaCyc: PWY-8004;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6886	"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Gluconeogenesis";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)"
XP_053984038.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053978438.1	16	Reactome: R-HSA-1963640;Reactome: R-HSA-1251985;Reactome: R-HSA-9664565;Reactome: R-HSA-2219530;Reactome: R-HSA-1250347;Reactome: R-HSA-6785631;Reactome: R-HSA-1250342;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-6811558;Reactome: R-HSA-1236394;Reactome: R-HSA-1963642;Reactome: R-HSA-1257604;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986	"GRB2 events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB4 signaling";"ERBB2 Regulates Cell Motility";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB4";"PI3K events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2"
XP_053974685.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053989876.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053973755.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-210744;Reactome: R-HSA-3899300	"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Circadian Clock";"RORA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors"
XP_053976990.1	7	Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6352;Reactome: R-HSA-1660516;MetaCyc: PWY-6351;Reactome: R-HSA-1660514	"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the early endosome membrane";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane"
XP_053989445.1	6	KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290	"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053973394.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053983183.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_053989688.1	7	Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2	"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism"
XP_053989017.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053992801.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053974448.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053988048.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053990852.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053983065.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions"
XP_053983419.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053981609.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053979959.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053975664.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053990230.1	7	Reactome: R-HSA-73817;MetaCyc: PWY-5695;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;MetaCyc: PWY-6596;Reactome: R-HSA-6798695;MetaCyc: PWY-7221	"Purine ribonucleoside monophosphate biosynthesis";"Inosine 5'-phosphate degradation";"Purine metabolism";"Drug metabolism - other enzymes";"Adenosine nucleotides degradation I";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis"
XP_053970685.1	12	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Thermogenesis";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"Rho GTPase cycle"
XP_053990119.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053977689.1	11	MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism"
XP_053989212.1	5	Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-6798695	"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"Neutrophil degranulation"
XP_053979748.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053981296.1	4	Reactome: R-HSA-3656532;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788	"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling"
XP_053982836.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053992457.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_053994640.1	6	Reactome: R-HSA-446199;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33	"Synthesis of Dolichyl-phosphate";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis"
XP_053988735.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_053988983.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053971795.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053981461.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053984745.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_053971464.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053994604.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053981351.1	20	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH"
XP_053974937.1	3	Reactome: R-HSA-8951664;Reactome: R-HSA-390471;Reactome: R-HSA-983168	"Neddylation";"Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053987126.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053972075.1	14	MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_053974213.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053974317.1	31	Reactome: R-HSA-75105;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;MetaCyc: PWY-8049;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-7746;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Fatty acyl-CoA biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Pederin biosynthesis";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Mycobacterial sulfolipid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis"
XP_053970937.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053976992.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-1268020	"Citric acid cycle (TCA cycle)";"Mitochondrial protein import"
XP_053980745.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053988345.1	2	Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43	"Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis"
XP_053990640.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_053977252.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053973654.1	4	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events"
XP_053983651.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_053985319.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053984234.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053991112.1	12	MetaCyc: PWY-7901;MetaCyc: PWY-801;MetaCyc: PWY-6309;MetaCyc: PWY-601;Reactome: R-HSA-71240;MetaCyc: PWY-6936;MetaCyc: PWY-1187;KEGG: 00450+4.4.1.13;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7;MetaCyc: PWY-6842;KEGG: 00270+4.4.1.13	"Glucosinolate biosynthesis from tyrosine";"Homocysteine and cysteine interconversion";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tryptophan";"Tryptophan catabolism";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from homomethionine";"Selenocompound metabolism";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism";"Glutathione-mediated detoxification II";"Cysteine and methionine metabolism"
XP_053974525.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053972844.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_053980602.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-8950505;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053991470.1	14	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-165054;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling"
XP_053988193.1	27	Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408	"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"ISG15 antiviral mechanism"
XP_053978384.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_053984602.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053982566.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053979536.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053980234.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053973108.1	6	KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;MetaCyc: PWY-6123;MetaCyc: PWY-7234	"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III"
XP_053986123.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_053971255.1	4	MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22	"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism"
XP_053975812.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053986551.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053988634.1	2	Reactome: R-HSA-8951671;Reactome: R-HSA-2032785	"RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression"
XP_053981691.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980421.1	2	Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions"
XP_053970424.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053971694.1	2	Reactome: R-HSA-6783310;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Protein ubiquitination"
XP_053981076.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-7456;Reactome: R-HSA-4043916;MetaCyc: PWY-6992	"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation"
XP_053987493.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_053986825.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_053982309.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053973576.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_053971886.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053972295.1	2	Reactome: R-HSA-6807004;Reactome: R-HSA-877312	"Negative regulation of MET activity";"Regulation of IFNG signaling"
XP_053971835.1	12	Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_053976455.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-2206305;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14	"Keratan sulfate degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"Glycosaminoglycan degradation"
XP_053974641.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053977529.1	8	Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053994705.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053975810.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053984854.1	10	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-437239;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"RSK activation";"Recycling pathway of L1";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection"
XP_053988202.1	56	Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556	"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport"
XP_053972802.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport"
XP_053976091.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053977790.1	56	Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895	"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis"
XP_053991818.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053975276.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053980600.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053983993.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053991472.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_053986719.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053992899.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053988024.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053977562.1	5	Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772	"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape"
XP_053986949.1	12	KEGG: 04150+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482	"mTOR signaling pathway";"Signaling by FGFR1 in disease";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by cytosolic FGFR1 fusion mutants";"Relaxin signaling pathway";"NRAGE signals death through JNK";"Thermogenesis";"Human papillomavirus infection";"Rho GTPase cycle";"Human cytomegalovirus infection";"G alpha (12/13) signalling events"
XP_053986187.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053991186.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053991135.1	9	Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"PPARA activates gene expression";"snRNP Assembly";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053981468.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_053976960.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053991670.1	56	Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_053987797.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053995110.1	8	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_053981358.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053990151.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053989744.1	4	Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053991253.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_053994314.1	6	Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-7382	"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053971118.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053984545.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053985691.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Macroautophagy"
XP_053986356.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7782	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis"
XP_053983095.1	10	Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538;Reactome: R-HSA-8936459;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022699;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9022692	"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"Regulation of MECP2 expression and activity"
XP_053979403.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053979331.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_053985076.1	7	Reactome: R-HSA-73780;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061	"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053975835.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)"
XP_053979548.1	11	Reactome: R-HSA-170670;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615	"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Purine metabolism";"PKA activation"
XP_053994151.1	4	MetaCyc: PWY-6987;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053992102.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053978517.1	8	KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_053977131.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053986972.1	3	KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_053976294.1	6	MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_053970906.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053975133.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053970703.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053971765.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053984444.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053978044.1	6	Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957	"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053973371.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053983807.1	4	Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695	"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation"
XP_053984031.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053978431.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_053971478.1	3	KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053974034.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053992100.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053980621.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053981491.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053981939.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053978000.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053993293.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053978303.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053972371.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053989702.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981055.1	1	Reactome: R-HSA-163560	"Triglyceride catabolism"
XP_053984621.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053986268.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053991833.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053992293.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_053975066.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053974703.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053987567.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053993100.1	6	Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473	"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint"
XP_053984310.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053983596.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053972776.1	2	Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1	"Vitamin B1 (thiamin) metabolism";"Purine metabolism"
XP_053989488.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985575.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053972973.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204	"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol"
XP_053990505.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053978638.1	13	KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.23;Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.23;Reactome: R-HSA-4085001;Reactome: R-HSA-2206308;Reactome: R-HSA-6798695	"Galactose metabolism";"HS-GAG degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Defective NEU1 causes sialidosis";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Other glycan degradation";"Sialic acid metabolism";"MPS IV - Morquio syndrome B";"Neutrophil degranulation"
XP_053979507.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053988085.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053971096.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053982619.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053974436.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053988036.1	4	Reactome: R-HSA-68884;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053988940.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053975795.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053993753.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053984428.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053983619.1	33	Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-159236	"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053970648.1	14	MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-5972;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-6598	"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Juniperonate biosynthesis";"Sciadonate biosynthesis"
XP_053975464.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053981409.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053985461.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053984930.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053980013.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053987770.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053991697.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053992820.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_053980310.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053978189.1	3	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214;Reactome: R-HSA-189085	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins";"Digestion of dietary carbohydrate"
XP_053979217.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167290	"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation"
XP_053979736.1	7	Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053987050.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex"
XP_053988942.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_053994404.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053978248.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053972101.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053976754.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053987463.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168325	"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis"
XP_053970584.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053993073.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053983658.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_053980226.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053988865.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053979524.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053987772.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053984932.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus"
XP_053982963.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053980312.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053984312.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053983104.1	7	Reactome: R-HSA-5368598;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-201681;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262	"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"WNT mediated activation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT";"RHO GTPases Activate Formins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_053975471.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_053980932.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_053994679.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053992847.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053983848.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053986997.1	52	Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-6803529;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-167242	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat"
XP_053983963.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053972056.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053978173.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994215.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053990404.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053994787.1	8	KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-5739	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-D-perosamine biosynthesis"
XP_053974334.1	5	Reactome: R-HSA-4719377;Reactome: R-HSA-162710;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4717374	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Synthesis of glycosylphosphatidylinositol (GPI)";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM1 causes DPM1-CDG (CDG-1e)"
XP_053970744.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053992103.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053986973.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053978300.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053976127.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053972519.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053993290.1	11	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053984403.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053978003.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053992964.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053973696.1	2	Reactome: R-HSA-204626;MetaCyc: PWY-5905	"Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis"
XP_053983074.1	9	Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-1362277;Reactome: R-HSA-68827;Reactome: R-HSA-69017;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Transcription of E2F targets under negative control by DREAM complex";"CDT1 association with the CDC6:ORC:origin complex";"CDK-mediated phosphorylation and removal of Cdc6";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin"
XP_053988341.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_053973071.1	29	Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_053978344.1	5	Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695	"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation"
XP_053992097.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053991252.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_053972071.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053982074.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_053982098.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_053981355.1	3	Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_053974914.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_053985826.1	2	Reactome: R-HSA-168138;Reactome: R-HSA-983231	"Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production"
XP_053972696.1	4	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68884	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Telophase/Cytokinesis"
XP_053981465.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053991138.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Peptide chain elongation"
XP_053984741.1	2	Reactome: R-HSA-83936;Reactome: R-HSA-2564830	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Cytosolic iron-sulfur cluster assembly"
XP_053989624.1	17	Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-8951664;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-2559582	"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Neddylation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)"
XP_053986989.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053976848.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053973558.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053974702.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983061.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893	"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase"
XP_053994799.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053989703.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053975509.1	1	KEGG: 00970+6.1.1.16	"Aminoacyl-tRNA biosynthesis"
XP_053971561.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053986265.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053995146.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053970681.1	12	KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK";"Thermogenesis";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection"
XP_053981058.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053976963.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053975258.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state"
XP_053983754.1	10	Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events"
XP_053982061.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_053984684.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053972064.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736	"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors"
XP_053971475.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053978302.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053971846.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053987692.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_053993292.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053973209.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053971768.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053975132.1	2	Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11	"Tryptophan catabolism";"Tryptophan metabolism"
XP_053992805.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_053986056.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053985376.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053977497.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053980507.1	13	MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254;MetaCyc: PWY-5913;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-561	"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_053972187.1	13	KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-7533;Reactome: R-HSA-196836;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00053+1.8.5.1	"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Gliotoxin biosynthesis";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Ascorbate and aldarate metabolism"
XP_053993070.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053989150.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053970645.1	14	Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_053976095.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053982960.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053980012.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053973291.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053975798.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053973972.1	3	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5656169	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis"
XP_053987053.1	3	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053984425.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053994508.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_053983278.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053990259.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053978170.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053986821.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053983116.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053987789.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053983960.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053972466.1	11	MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.9	"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Purine metabolism"
XP_053981695.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053986199.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053973187.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_053979046.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053994701.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1482798	"Mitochondrial protein import";"Acyl chain remodeling of CL"
XP_053984012.1	8	MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7198;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_053989436.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053981834.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053972972.1	9	MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-416476	"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"G alpha (q) signalling events"
XP_053972291.1	3	Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228	"Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix"
XP_053986454.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053976451.1	4	Reactome: R-HSA-379716;KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10	"Cytosolic tRNA aminoacylation";"Selenocompound metabolism";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053982278.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053977966.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_053993277.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_053987677.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053990416.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053978894.1	3	MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)"
XP_053985764.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_053978172.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053980524.1	7	KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984;MetaCyc: PWY-31;MetaCyc: PWY-6922;MetaCyc: PWY-46;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635	"Arginine and proline metabolism";"Urea cycle";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Arginine biosynthesis";"Urea cycle"
XP_053971709.1	12	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4"
XP_053979226.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_053989725.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_053979312.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053971396.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_053977470.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_053988336.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053971251.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_053983845.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053986555.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053984346.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053980736.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053984313.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053985106.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053979581.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167161;Reactome: R-HSA-77075	"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_053974728.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_053977112.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_053987429.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053970286.1	2	MetaCyc: PWY-7800;MetaCyc: PWY-7799	"Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)"
XP_053974286.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_053975568.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_053976374.1	2	KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205	"Starch and sucrose metabolism";"Synthesis of GDP-mannose"
XP_053986371.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053970728.1	7	Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Pyruvate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053993072.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053984217.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_053980346.1	2	Reactome: R-HSA-192456;Reactome: R-HSA-975634	"Digestion of dietary lipid";"Retinoid metabolism and transport"
XP_053972268.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053980313.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053983655.1	3	Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257	"TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN"
XP_053988868.1	3	Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway"
XP_053980010.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053975054.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053984933.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_053973970.1	19	Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825	"LDL remodeling";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Chylomicron assembly";"Platelet sensitization by LDL";"LDL clearance";"Chylomicron clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"VLDL assembly";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis"
XP_053988943.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_053988160.1	4	Reactome: R-HSA-9615710;Reactome: R-HSA-9613829;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300	"Late endosomal microautophagy";"Chaperone Mediated Autophagy";"Aggrephagy";"SUMOylation of transcription cofactors"
XP_053994680.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053978328.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053980086.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984625.1	5	Reactome: R-HSA-901032;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346	"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis"
XP_053974210.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053973666.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053986844.1	2	Reactome: R-HSA-2022377;Reactome: R-HSA-6798695	"Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation"
XP_053994643.1	7	KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism"
XP_053992994.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053978167.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053973123.1	2	Reactome: R-HSA-2564830;Reactome: R-HSA-5693554	"Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053992067.1	6	Reactome: R-HSA-8866654;Reactome: R-HSA-5632684;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"E3 ubiquitin ligases ubiquitinate target proteins";"Hedgehog 'on' state";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_053972758.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053990599.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_053974876.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053989503.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053973375.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053993049.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_053990720.1	10	MetaCyc: PWY-6891;MetaCyc: PWY-6901;KEGG: 00710+2.2.1.1;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.1;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560	"Thiazole biosynthesis II (aerobic bacteria)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_053975396.1	2	Reactome: R-HSA-380095;Reactome: R-HSA-416476	"Tachykinin receptors bind tachykinins";"G alpha (q) signalling events"
XP_053974688.1	2	Reactome: R-HSA-400253;Reactome: R-HSA-2151201	"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis"
XP_053988417.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053974017.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053982068.1	20	Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"Translesion synthesis by POLI";"Polymerase switching";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053989448.1	6	Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-913709;MetaCyc: PWY-7290	"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis"
XP_053973758.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-381340	"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RORA activates gene expression";"Circadian Clock";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation"
XP_053984086.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053982977.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053993978.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_053982554.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053978435.1	2	KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336	"Pentose phosphate pathway";"Pentose phosphate pathway"
XP_053993994.1	16	Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174154	"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin"
XP_053990337.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053983676.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053990722.1	2	Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22	"Histidine catabolism";"Histidine metabolism"
XP_053988348.1	8	KEGG: 00900+1.1.1.34;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-6174	"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway II (archaea)"
XP_053977253.1	18	MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;KEGG: 00592+3.1.1.4	"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PI";"alpha-Linolenic acid metabolism"
XP_053988225.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053986295.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053971591.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-3299685;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111463;Reactome: R-HSA-2151201;Reactome: R-HSA-9627069;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Detoxification of Reactive Oxygen Species";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC (DIABLO) binds to IAPs";"Transcriptional activation of mitochondrial biogenesis";"Regulation of the apoptosome activity";"Respiratory electron transport"
XP_053988531.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053977186.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053983888.1	13	Reactome: R-HSA-182218;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825	"Nef Mediated CD8 Down-regulation";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis"
XP_053978534.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053992887.1	3	Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928	"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2"
XP_053976993.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053970326.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053986802.1	20	MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-5136;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-6920	"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)"
XP_053992229.1	58	Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5689901;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425	"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Metalloprotease DUBs";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1"
XP_053974326.1	4	Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_053972078.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053974212.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053984748.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_053991131.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-191859;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-1368082	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"snRNP Assembly";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"RORA activates gene expression"
XP_053977357.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053988738.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_053971798.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053984866.1	11	MetaCyc: PWY-922;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-6859;MetaCyc: PWY-6174;MetaCyc: PWY-7560;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7391;MetaCyc: PWY-7102;MetaCyc: PWY-5123;MetaCyc: PWY-6383	"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"All-trans-farnesol biosynthesis";"Mevalonate pathway II (archaea)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Bisabolene biosynthesis (engineered)";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis"
XP_053972949.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053986576.1	2	Reactome: R-HSA-8854214;Reactome: R-HSA-977225	"TBC/RABGAPs";"Amyloid fiber formation"
XP_053988982.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053982888.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053972719.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053991954.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-5620922;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053988546.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_053982009.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053982990.1	11	Reactome: R-HSA-75953;Reactome: R-HSA-5689880;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Initiation";"Ub-specific processing proteases";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events"
XP_053986122.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_053976419.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053979588.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053973105.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053975475.1	5	MetaCyc: PWY-7761;MetaCyc: PWY-5381;Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653	"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde"
XP_053995057.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053989407.1	6	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization"
XP_053988192.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053975768.1	11	MetaCyc: PWY-6907;Reactome: R-HSA-196819;Reactome: R-HSA-381426;Reactome: R-HSA-532668;MetaCyc: PWY-7356;Reactome: R-HSA-8957275;KEGG: 00730+2.7.6.2;Reactome: R-HSA-879415;Reactome: R-HSA-901042;MetaCyc: PWY-6908;MetaCyc: PWY-6898	"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Thiamine salvage IV (yeast)";"Post-translational protein phosphorylation";"Thiamine metabolism";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III"
XP_053981376.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053984603.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053989231.1	10	KEGG: 00670+2.1.1.45;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-3841;MetaCyc: PWY-7187;MetaCyc: PWY-7199;Reactome: R-HSA-69205	"One carbon pool by folate";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleosides salvage";"G1/S-Specific Transcription"
XP_053972105.1	1	KEGG: 00450+1.8.1.9	"Selenocompound metabolism"
XP_053992550.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-912526;Reactome: R-HSA-114604;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"Rho GTPase cycle";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"Interleukin receptor SHC signaling";"GPVI-mediated activation cascade";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer"
XP_053988324.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053989784.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053991592.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053972496.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053986378.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053971509.1	7	Reactome: R-HSA-71336;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-5514	"Pentose phosphate pathway";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_053980724.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053976183.1	1	Reactome: R-HSA-5625900	"RHO GTPases activate CIT"
XP_053978864.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation"
XP_053991760.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053985058.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053988861.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053982264.1	60	Reactome: R-HSA-1482798;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00280+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00930+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7654;MetaCyc: PWY-6863;MetaCyc: PWY-6946;KEGG: 00310+4.2.1.17;KEGG: 00640+4.2.1.17;Reactome: R-HSA-77305;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6435;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00281+4.2.1.17;MetaCyc: PWY-7778;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7726;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77348;KEGG: 00380+4.2.1.17;MetaCyc: PWY-7606;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;Reactome: R-HSA-77288;MetaCyc: PWY-6944;MetaCyc: PWY-6945;MetaCyc: PWY-6883;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00362+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7779;KEGG: 00310+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00071+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;KEGG: 00410+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7401;MetaCyc: PWY-1361;Reactome: R-HSA-77350	"Acyl chain remodeling of CL";"Fatty acid elongation";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Phenylalanine metabolism";"Caprolactam degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Benzoate degradation";"Limonene and pinene degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Lysine degradation";"Propanoate metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Aminobenzoate degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid degradation";"Geraniol degradation";"2-methylpropene degradation";"Geraniol degradation";"Pyruvate fermentation to butanol I";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Tryptophan metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Butanoate metabolism";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"Glutaryl-coa degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Androstenedione degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Pyruvate fermentation to butanol II (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"Fatty acid salvage";"Fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine degradation";"Spodoptera littoralis pheromone biosynthesis";"Benzoate degradation";"Caprolactam degradation";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Methyl tert-butyl ether degradation";"Lysine degradation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fatty acid degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"beta-Alanine metabolism";"Fatty acid elongation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Benzoyl-coa degradation I (aerobic)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA"
XP_053983271.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053983992.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053975791.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053971456.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_053989851.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_053980484.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_053984707.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053971366.1	10	Reactome: R-HSA-977225;MetaCyc: PWY-7394;Reactome: R-HSA-6798695;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-975634;Reactome: R-HSA-3000171;Reactome: R-HSA-2453902	"Amyloid fiber formation";"Urate conversion to allantoin II";"Neutrophil degranulation";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"Purine metabolism";"Retinoid metabolism and transport";"Non-integrin membrane-ECM interactions";"The canonical retinoid cycle in rods (twilight vision)"
XP_053991473.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_053991590.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053979421.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695	"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation"
XP_053985355.1	2	Reactome: R-HSA-1632852;Reactome: R-HSA-5689880	"Macroautophagy";"Ub-specific processing proteases"
XP_053987589.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-5689880	"Protein ubiquitination";"Ub-specific processing proteases"
XP_053991762.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053995138.1	3	Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3	"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism"
XP_053985465.1	17	KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-7383;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913	"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)"
XP_053981826.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053971219.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053994708.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053988307.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_053988898.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-111367	"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"SLBP independent Processing of Histone Pre-mRNAs"
XP_053977697.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053971838.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053986828.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_053988081.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053990501.1	9	Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3656532	"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGFBR1 KD Mutants in Cancer"
XP_053987492.1	5	Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321	"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1"
XP_053972683.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053980136.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053984063.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053985706.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053984879.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-983231;Reactome: R-HSA-6811436	"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053982647.1	2	Reactome: R-HSA-5663220;Reactome: R-HSA-376176	"RHO GTPases Activate Formins";"Signaling by ROBO receptors"
XP_053975205.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053986569.1	10	MetaCyc: PWY-6361;MetaCyc: PWY-6554;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6369	"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053974128.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053970372.1	25	Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-500657;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-381771;Reactome: R-HSA-392451;Reactome: R-HSA-392170	"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"G alpha (z) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"Presynaptic function of Kainate receptors";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12"
XP_053983622.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053971981.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053972442.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053983857.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053979062.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053989125.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053988489.1	5	Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20	"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Neutrophil degranulation";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053988760.1	4	Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198	"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis"
XP_053983647.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_053994776.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053993150.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053973683.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053973505.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053974753.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053971532.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053991324.1	18	Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_053975414.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053978257.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053983669.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053984185.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053987173.1	10	Reactome: R-HSA-8856828;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-182971	"Clathrin-mediated endocytosis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Ub-specific processing proteases";"Inhibition of membrane repair";"EGFR downregulation"
XP_053980360.1	3	Reactome: R-HSA-6783310;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Fanconi Anemia Pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053977927.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053988762.1	4	Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289	"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation"
XP_053983401.1	3	Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638	"RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_053981611.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053971614.1	3	MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2	"Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism"
XP_053993152.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053987413.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_053972787.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053988815.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053979249.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053972215.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_053985537.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053974073.1	7	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_053994056.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Cyclin D associated events in G1";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway"
XP_053978837.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111469;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111457	"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria"
XP_053992584.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053982030.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053973679.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_053987028.1	4	KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963	"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I"
XP_053982333.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-983231	"Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production"
XP_053976011.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053988729.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_053984362.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053977710.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053991190.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053994989.1	4	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes"
XP_053984452.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053979453.1	7	Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-429947;Reactome: R-HSA-156827	"Translation initiation complex formation";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053992238.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053983620.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053983743.1	2	KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600	"Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"
XP_053991307.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053993584.1	22	Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-196299;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-5467340	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex"
XP_053978770.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053983913.1	1	Reactome: R-HSA-2467813	"Separation of Sister Chromatids"
XP_053970847.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053979363.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053972440.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053980329.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053979060.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053973215.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053981418.1	3	KEGG: 00480+4.3.2.7;Reactome: R-HSA-174403;MetaCyc: PWY-7942	"Glutathione metabolism";"Glutathione synthesis and recycling";"5-oxo-L-proline metabolism"
XP_053970539.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_053987044.1	7	MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817;KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121	"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_053989103.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053976623.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053982499.1	7	KEGG: 00010+2.3.1.12;Reactome: R-HSA-389661;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-70268	"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Pyruvate metabolism"
XP_053976740.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053972934.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053981872.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053995160.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-5689880	"Mitochondrial calcium ion transport";"Ub-specific processing proteases"
XP_053976910.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6906;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II"
XP_053987303.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981633.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981506.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053975223.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053986701.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053972523.1	6	Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16	"Circadian Clock";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053976704.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053987431.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053987999.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053985925.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053973934.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450	"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion"
XP_053983499.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_053972006.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_053975732.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053971168.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053975988.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_053991417.1	7	MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367	"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism"
XP_053986416.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053985849.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053982608.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053981320.1	6	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053987207.1	6	MetaCyc: PWY-4381;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6722	"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Candicidin biosynthesis"
XP_053982311.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_053972314.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053976033.1	8	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_053976330.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling"
XP_053983154.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_053971860.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053986508.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053991045.1	20	Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091	"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching"
XP_053982580.1	2	KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281	"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)"
XP_053989292.1	2	Reactome: R-HSA-6811436;Reactome: R-HSA-8876198	"COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs"
XP_053981243.1	5	Reactome: R-HSA-380994;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-9614657	"ATF4 activates genes in response to endoplasmic reticulum stress";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes"
XP_053979557.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053992624.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053990555.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053992906.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053984995.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053986176.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_053976727.1	7	Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346	"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog ligand biogenesis"
XP_053970808.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053974293.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_053981369.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053976742.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053983580.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_053986218.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053975877.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053976912.1	4	MetaCyc: PWY-6906;Reactome: R-HSA-446210;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59	"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism"
XP_053971080.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053981178.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053981194.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053985618.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053987002.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053985087.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053993703.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053981347.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053975043.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053981433.1	1	Reactome: R-HSA-5617472	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053983543.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053978570.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053993784.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053978493.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053986599.1	13	Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-8943724;Reactome: R-HSA-166208	"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"HSF1-dependent transactivation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"mTOR signalling";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling"
XP_053993231.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_053985369.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053975191.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053981087.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053975383.1	10	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_053983408.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053990800.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_053975080.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053971043.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053984107.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_053977510.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_053977895.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053980107.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053991891.1	12	Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-2644606;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-210744	"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HATs acetylate histones";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_053985243.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053985322.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053975715.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053994800.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053987908.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053992784.1	6	KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-1268020	"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"ATP biosynthesis";"Mitochondrial protein import"
XP_053988562.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053983699.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053987021.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053986616.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053986720.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053993407.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053979297.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_053990295.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985320.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053981849.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053992851.1	57	Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751	"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity"
XP_053985023.1	2	Reactome: R-HSA-2024096;Reactome: R-HSA-2206307	"HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A"
XP_053971988.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_053988560.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053991385.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_053994576.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053983206.1	4	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053986337.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053995045.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053973705.1	4	Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118	"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation"
XP_053984124.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_053974553.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053981867.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053976986.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053980124.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_053993851.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053979909.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_053991868.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053975082.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053986155.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053994295.1	5	MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2	"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism"
XP_053977512.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_053979090.1	3	KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857	"Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis"
XP_053971342.1	7	Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-212300	"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"HCMV Early Events";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA"
XP_053986769.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053972037.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-68962	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"DNA replication initiation";"Activation of the pre-replicative complex"
XP_053991341.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-110314	"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053977786.1	57	Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556	"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport"
XP_053994169.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053983422.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053977735.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053980804.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053989049.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053972642.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053976196.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053995081.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053988689.1	6	Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317	"Defective GALT can cause Galactosemia";"Galactose catabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053993685.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053982015.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053980377.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053973627.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_053973230.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053978663.1	14	MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;Reactome: R-HSA-4419969;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;Reactome: R-HSA-75109;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4	"Stigma estolide biosynthesis";"Ether lipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"Depolymerisation of the Nuclear Lamina";"Glycerolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Sphingolipid metabolism"
XP_053972483.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053978126.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053992026.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_053990122.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053994378.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_053980840.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053982447.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053973852.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053989067.1	3	Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis"
XP_053994394.1	14	Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985	"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4"
XP_053980650.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053985611.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053992636.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_053983015.1	1	Reactome: R-HSA-2173788	"Downregulation of TGF-beta receptor signaling"
XP_053994122.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-4086398	"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway"
XP_053981171.1	3	MetaCyc: PWY-5987;Reactome: R-HSA-75105;MetaCyc: PWY-5996	"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)"
XP_053971174.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053992503.1	7	KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661	"Lysine degradation";"Citrate cycle (TCA cycle)";"Lysine catabolism";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation"
XP_053983359.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_053979145.1	13	KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7184;KEGG: 00500+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-6545;KEGG: 00760+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7206	"Purine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Starch and sucrose metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Pyrimidine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation"
XP_053980273.1	3	KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160	"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions"
XP_053983447.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053984377.1	3	Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300	"SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors"
XP_053988252.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053978597.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053977228.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_053984148.1	3	KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693	"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism"
XP_053988830.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053985897.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053980652.1	5	MetaCyc: PWY-7921;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109	"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis"
XP_053979968.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053994120.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398	"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway"
XP_053984842.1	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-5531	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)"
XP_053984289.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053989262.1	11	Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_053973926.1	4	Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1"
XP_053980827.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053987438.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053992317.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053983318.1	1	Reactome: R-HSA-191273	"Cholesterol biosynthesis"
XP_053986708.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053982782.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_053977048.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-606279	"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053989887.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053973604.1	16	Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692	"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of MECP2 expression and activity"
XP_053970457.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053988250.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6811434	"Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053981411.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053985005.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053974263.1	11	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053970367.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053979843.1	4	KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
XP_053981903.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359	"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation"
XP_053983420.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053982318.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_053972640.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053972723.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053988057.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053971161.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053973479.1	8	Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_053973232.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053970739.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053981164.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_053974349.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053980289.1	16	Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-9010553	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Regulation of expression of SLITs and ROBOs"
XP_053980842.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053977426.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053982601.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053973850.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053978639.1	13	Reactome: R-HSA-4085001;Reactome: R-HSA-2206308;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2022857;KEGG: 00600+3.2.1.23;Reactome: R-HSA-4341670;KEGG: 00531+3.2.1.23	"Sialic acid metabolism";"MPS IV - Morquio syndrome B";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism";"HS-GAG degradation";"Keratan sulfate degradation";"Sphingolipid metabolism";"Defective NEU1 causes sialidosis";"Glycosaminoglycan degradation"
XP_053972340.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053977235.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053979463.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs"
XP_053986195.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980429.1	33	MetaCyc: PWY-5076;KEGG: 00592+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-5751;MetaCyc: PWY-5486;KEGG: 00626+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-1801;MetaCyc: PWY-5480;MetaCyc: PWY-7111;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6587;KEGG: 00350+1.1.1.1;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-6333;KEGG: 00830+1.1.1.1;MetaCyc: PWY-6342;MetaCyc: PWY-7013;Reactome: R-HSA-71384;MetaCyc: PWY-5078;KEGG: 00010+1.1.1.1;KEGG: 00980+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-7396;MetaCyc: PWY-6313;MetaCyc: PWY-5079;KEGG: 00982+1.1.1.1;MetaCyc: PWY-7798;KEGG: 00625+1.1.1.1;MetaCyc: PWY-3162;MetaCyc: PWY-5057	"L-leucine degradation III";"alpha-Linolenic acid metabolism";"3-methylbutanol biosynthesis (engineered)";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol II";"Naphthalene degradation";"Glycine, serine and threonine metabolism";"Chitin degradation to ethanol";"Formaldehyde oxidation II (glutathione-dependent)";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to isobutanol (engineered)";"Methane metabolism";"Pyruvate fermentation to ethanol III";"Tyrosine metabolism";"Fatty acid degradation";"L-methionine degradation III";"Acetaldehyde biosynthesis I";"Retinol metabolism";"Noradrenaline and adrenaline degradation";"(S)-propane-1,2-diol degradation";"Ethanol oxidation";"L-isoleucine degradation II";"Glycolysis / Gluconeogenesis";"Metabolism of xenobiotics by cytochrome P450";"Salidroside biosynthesis";"Butanol and isobutanol biosynthesis (engineered)";"Serotonin degradation";"L-phenylalanine degradation III";"Drug metabolism - cytochrome P450";"Protein S-nitrosylation and denitrosylation";"Chloroalkane and chloroalkene degradation";"L-tryptophan degradation V (side chain pathway)";"L-valine degradation II"
XP_053977286.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053979353.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053984976.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053987217.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_053993088.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053979050.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053993617.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053982618.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053988277.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053970470.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_053972877.1	24	Reactome: R-HSA-163615;Reactome: R-HSA-5687128;Reactome: R-HSA-9634600;Reactome: R-HSA-180024;Reactome: R-HSA-392517;Reactome: R-HSA-8963896;Reactome: R-HSA-163560;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-5621575;Reactome: R-HSA-4420097;Reactome: R-HSA-983231;Reactome: R-HSA-432040;Reactome: R-HSA-422356;Reactome: R-HSA-111931;Reactome: R-HSA-163358;Reactome: R-HSA-5610785;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5610783;Reactome: R-HSA-9010642;Reactome: R-HSA-164378;Reactome: R-HSA-8853659;Reactome: R-HSA-5610780	"PKA activation";"MAPK6/MAPK4 signaling";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"DARPP-32 events";"Rap1 signalling";"HDL assembly";"Triglyceride catabolism";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CD209 (DC-SIGN) signaling";"VEGFA-VEGFR2 Pathway";"Factors involved in megakaryocyte development and platelet production";"Vasopressin regulates renal water homeostasis via Aquaporins";"Regulation of insulin secretion";"PKA-mediated phosphorylation of CREB";"PKA-mediated phosphorylation of key metabolic factors";"GLI3 is processed to GLI3R by the proteasome";"mTOR signaling pathway";"Degradation of GLI2 by the proteasome";"ROBO receptors bind AKAP5";"PKA activation in glucagon signalling";"RET signaling";"Degradation of GLI1 by the proteasome"
XP_053983280.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_053984462.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053989489.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053980462.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_053981408.1	5	KEGG: 04660+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053976099.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053989113.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053992088.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053989146.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053970649.1	5	Reactome: R-HSA-6802955;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221;Reactome: R-HSA-9649948	"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway";"Signaling downstream of RAS mutants"
XP_053974593.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053988070.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053990255.1	9	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER"
XP_053978880.1	7	Reactome: R-HSA-3214815;Reactome: R-HSA-983231;Reactome: R-HSA-8943724;Reactome: R-HSA-5625886;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519	"HDACs deacetylate histones";"Factors involved in megakaryocyte development and platelet production";"Regulation of PTEN gene transcription";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression"
XP_053970667.1	24	Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;Reactome: R-HSA-202424;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-5674400;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-5607764	"FCERI mediated NF-kB activation";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"RSK activation";"Regulation of TP53 Degradation";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Constitutive Signaling by AKT1 E17K in Cancer";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"CLEC7A (Dectin-1) signaling"
XP_053983433.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053989592.1	3	KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646	"Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification"
XP_053982280.1	30	Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-211163;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389513;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8876198;Reactome: R-HSA-6804758;Reactome: R-HSA-1358803;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-111447;Reactome: R-HSA-69202;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-199418;Reactome: R-HSA-8941332;Reactome: R-HSA-198323;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-389357;Reactome: R-HSA-9634638;Reactome: R-HSA-5628897;Reactome: R-HSA-198693	"Regulation of TP53 Degradation";"mTOR signaling pathway";"AKT-mediated inactivation of FOXO1A";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"CTLA4 inhibitory signaling";"Relaxin signaling pathway";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TP53 Activity through Acetylation";"Downregulation of ERBB2:ERBB3 signaling";"Thermogenesis";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Human cytomegalovirus infection";"VEGFR2 mediated vascular permeability";"Activation of BAD and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"PI3K-Akt signaling pathway";"Regulation of PTEN stability and activity";"Negative regulation of the PI3K/AKT network";"RUNX2 regulates genes involved in cell migration";"AKT phosphorylates targets in the cytosol";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"CD28 dependent PI3K/Akt signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the nucleus"
XP_053983301.1	7	MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_053986711.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053978029.1	6	Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053971587.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053986941.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053993868.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053983659.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_053973223.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053980350.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053988072.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053974472.1	18	Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_053975314.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053992336.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053976902.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053992385.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053977645.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6784531	"Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus"
XP_053989815.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053972327.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053978249.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053993160.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684	"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state"
XP_053984677.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053972732.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_053993713.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053972342.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053993336.1	12	MetaCyc: PWY-5872;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-5857;MetaCyc: PWY-5871	"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_053975151.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053992868.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053988823.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053991641.1	17	Reactome: R-HSA-167287;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"T cell receptor signaling pathway";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_053987425.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053978453.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053985499.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053979770.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053970472.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-1433559	"Neddylation";"Regulation of KIT signaling"
XP_053992713.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053992746.1	2	Reactome: R-HSA-6793080;Reactome: R-HSA-2151201	"rRNA modification in the mitochondrion";"Transcriptional activation of mitochondrial biogenesis"
XP_053973732.1	15	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks"
XP_053986893.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_053973988.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053973327.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053984460.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053983282.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053975440.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053993284.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053984692.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053971483.1	7	Reactome: R-HSA-1483213;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-3385;MetaCyc: PWY-7886	"Synthesis of PE";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PC";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_053983171.1	1	Reactome: R-HSA-6806664	"Metabolism of vitamin K"
XP_053981469.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490	"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation"
XP_053987896.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053988964.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_053971037.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_053985237.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170	"ECM proteoglycans";"Integrin cell surface interactions";"Molecules associated with elastic fibres";"Syndecan interactions"
XP_053979549.1	11	Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-5610787	"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"Hedgehog 'off' state"
XP_053985913.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053992284.1	33	Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159227	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA"
XP_053975787.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_053981780.1	16	Reactome: R-HSA-182218;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-177504;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-8964038;Reactome: R-HSA-164939;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825	"Nef Mediated CD8 Down-regulation";"Gap junction degradation";"Formation of annular gap junctions";"Retrograde neurotrophin signalling";"Recycling pathway of L1";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"LDL clearance";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis"
XP_053971852.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053976432.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053971119.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053972174.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_053986220.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053991636.1	10	KEGG: 00562+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-6142;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Inositol phosphate metabolism";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis";"Gluconeogenesis"
XP_053986637.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053988292.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585	"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G"
XP_053988971.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053978557.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053981938.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053983164.1	20	Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-166208	"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Regulation of TP53 Degradation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Regulation of PTEN gene transcription";"Thermogenesis";"mTORC1-mediated signalling"
XP_053971479.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_053971850.1	2	Reactome: R-HSA-388479;Reactome: R-HSA-416476	"Vasopressin-like receptors";"G alpha (q) signalling events"
XP_053991317.1	18	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_053986343.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053983903.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Dual incision in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation"
XP_053987741.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053976387.1	16	Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
XP_053987911.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053986222.1	12	KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5871	"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_053983411.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053975442.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053994464.1	3	Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691	"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway";"Interleukin-20 family signaling"
XP_053971604.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981601.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053991937.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053986936.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_053987403.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053986247.1	18	MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922	"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Synthesis of PA";"Acyl chain remodelling of PI"
XP_053972161.1	42	KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6583;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00592+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;MetaCyc: PWY-7606;MetaCyc: PWY-7216;KEGG: 00623+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;KEGG: 00410+4.2.1.17;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-1361;MetaCyc: PWY-7401;MetaCyc: PWY-6945;MetaCyc: PWY-6944;MetaCyc: PWY-7007;MetaCyc: PWY-5109;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;MetaCyc: PWY-5136;MetaCyc: PWY-6883;MetaCyc: PWY-6863;MetaCyc: PWY-7654;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;KEGG: 00627+4.2.1.17;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7656;MetaCyc: PWY-6435	"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol I";"Geraniol degradation";"Butanoate metabolism";"2-methylpropene degradation";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Toluene degradation";"Lysine degradation";"Methyl tert-butyl ether degradation";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate/4-hydroxybutanate cycle";"beta-Alanine metabolism";"Fatty acid elongation";"Fatty acid degradation";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Androstenedione degradation";"Methyl ketone biosynthesis (engineered)";"Fermentation to 2-methylbutanoate";"Fatty acid degradation";"Fatty acid salvage";"Tryptophan metabolism";"Phenylalanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Pyruvate fermentation to butanol II (engineered)";"Pyruvate fermentation to hexanol (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoate degradation";"Limonene and pinene degradation";"Valine, leucine and isoleucine degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Aminobenzoate degradation";"Propanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)"
XP_053989131.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053982399.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053985647.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053986269.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053975505.1	6	Reactome: R-HSA-6803211;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205	"TP53 Regulates Transcription of Death Receptors and Ligands";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_053985032.1	5	Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159231	"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript"
XP_053994795.1	2	Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7	"Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053985601.1	1	Reactome: R-HSA-2142789	"Ubiquinol biosynthesis"
XP_053975604.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053992513.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053972981.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-450604;Reactome: R-HSA-380994	"Deadenylation of mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053982984.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053983005.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053975640.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053975926.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_053984814.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053989529.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_053978092.1	5	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER"
XP_053984492.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053985318.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053976204.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053991150.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053988550.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy"
XP_053994671.1	4	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-1912420	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi"
XP_053981622.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053991485.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053987707.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053970811.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053992324.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053981857.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053993546.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053991436.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565	"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_053982005.1	27	Reactome: R-HSA-168276;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-6784531	"NS1 Mediated Effects on Host Pathways";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus"
XP_053973981.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053974563.1	7	Reactome: R-HSA-210500;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2	"Glutamate Neurotransmitter Release Cycle";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism"
XP_053985420.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_053976632.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053991584.1	9	Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6782315	"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"tRNA modification in the nucleus and cytosol"
XP_053981946.1	3	MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053982308.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053993898.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053982897.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053980490.1	4	KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48	"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes"
XP_053980573.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981620.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053976514.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053972530.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression"
XP_053990664.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053989560.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053976175.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053985422.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053982611.1	15	Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262	"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_053993081.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053976227.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053992874.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_053987724.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053991238.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_053983897.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053992898.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053994664.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053975642.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053985469.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053985015.1	4	Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257	"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion"
XP_053993203.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins"
XP_053978090.1	5	Reactome: R-HSA-6783310;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135	"Fanconi Anemia Pathway";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER"
XP_053978181.1	7	Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination"
XP_053985359.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053988184.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053978393.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053981154.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980117.1	10	MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11	"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_053994810.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053974449.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053988049.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053975705.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053972082.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053989689.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053988994.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053979663.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"T cell receptor signaling pathway"
XP_053978272.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053987866.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053978439.1	16	Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1250196;Reactome: R-HSA-1250342;Reactome: R-HSA-1963642;Reactome: R-HSA-6811558;Reactome: R-HSA-1236394;Reactome: R-HSA-2219530;Reactome: R-HSA-6785631;Reactome: R-HSA-1250347;Reactome: R-HSA-1963640;Reactome: R-HSA-9664565;Reactome: R-HSA-1251985	"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"PI3K events in ERBB2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"Nuclear signaling by ERBB4"
XP_053980629.1	17	MetaCyc: PWY-6627;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;KEGG: 00240+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-5532;Reactome: R-HSA-74259;Reactome: R-HSA-6798695;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609	"Salinosporamide A biosynthesis";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Guanosine nucleotides degradation III";"Pyrimidine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Purine catabolism";"Neutrophil degranulation";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III"
XP_053980955.1	4	MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-6829	"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)"
XP_053970467.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Degradation of AXIN";"Ub-specific processing proteases"
XP_053972860.1	3	Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism"
XP_053988260.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053973082.1	6	Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788;Reactome: R-HSA-983168	"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984629.1	56	Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323	"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling"
XP_053970357.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053987541.1	24	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Gap junction assembly";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_053981311.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053978145.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)"
XP_053971314.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053978757.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053993980.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_053990595.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053982320.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_053970449.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053990810.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053979597.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053983418.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053984117.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053983872.1	2	Reactome: R-HSA-191859;Reactome: R-HSA-6807505	"snRNP Assembly";"RNA polymerase II transcribes snRNA genes"
XP_053983178.1	8	Reactome: R-HSA-73614;MetaCyc: PWY-6556;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7193;MetaCyc: PWY-7181;MetaCyc: PWY-7199	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage"
XP_053992177.1	13	MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_053973080.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053988262.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053978077.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-165159	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"mTOR signalling"
XP_053992225.1	5	Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)"
XP_053972715.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053990812.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053977688.1	11	MetaCyc: PWY-8052;MetaCyc: PWY-8055;Reactome: R-HSA-2029485;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4	"2-arachidonoylglycerol biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Role of phospholipids in phagocytosis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism"
XP_053979749.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053972287.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053972945.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053987035.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878	"COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport"
XP_053991624.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053990494.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053978843.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs"
XP_053975587.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-177929;Reactome: R-HSA-1442490	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Signaling by EGFR";"Collagen degradation"
XP_053982216.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053982737.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053982243.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053983369.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053993225.1	8	MetaCyc: PWY-7533;MetaCyc: PWY-4061;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842	"Gliotoxin biosynthesis";"Glutathione-mediated detoxification I";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II"
XP_053988229.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053994494.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053972191.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053993177.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053982870.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053983216.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053993531.1	9	KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_053973287.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053989538.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053988607.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053983106.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_053983495.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053979003.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_053991978.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053973761.1	26	Reactome: R-HSA-400253;Reactome: R-HSA-210744;Reactome: R-HSA-3899300;Reactome: R-HSA-1368082;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-933541;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-9018519;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-2894862	"Circadian Clock";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors";"RORA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"TRAF6 mediated IRF7 activation";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"Estrogen-dependent gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053975268.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053972054.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053985962.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053990406.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053972568.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053980517.1	14	KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_053970586.1	6	Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368	"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_053976756.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053976953.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053980002.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053970535.1	3	Reactome: R-HSA-1660516;Reactome: R-HSA-1660517;Reactome: R-HSA-1660514	"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane"
XP_053990711.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053979526.1	2	Reactome: R-HSA-202733;Reactome: R-HSA-416993	"Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors"
XP_053972761.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691	"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)"
XP_053991260.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053975291.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053981365.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053993954.1	4	KEGG: 00513+3.2.1.113;MetaCyc: PWY-7919;Reactome: R-HSA-901032;KEGG: 00510+3.2.1.113	"Various types of N-glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"ER Quality Control Compartment (ERQC)";"N-Glycan biosynthesis"
XP_053986835.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053975466.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994559.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_053995070.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960	"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC"
XP_053971825.1	9	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053977539.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053976691.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053991262.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_053971719.1	7	Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-69231	"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin D associated events in G1"
XP_053983578.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_053984044.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053995125.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053974041.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053981676.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053981180.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053984999.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-8986944	"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2"
XP_053988034.1	2	KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10	"Glycine, serine and threonine metabolism";"One carbon pool by folate"
XP_053971078.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053971094.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053981091.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053975187.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980638.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053984028.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053974940.1	13	Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-937042	"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex"
XP_053980413.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053977822.1	7	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins"
XP_053984189.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053975558.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053994637.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469	"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis"
XP_053983665.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053977657.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053984901.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641258	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL"
XP_053974904.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053975064.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053985061.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053981009.1	9	Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779	"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"
XP_053981264.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053977847.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053979170.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053980901.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053992760.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_053970904.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053984875.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053994027.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism"
XP_053984413.1	16	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053978013.1	14	KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;Reactome: R-HSA-975634;MetaCyc: PWY-7416	"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)"
XP_053984446.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053978046.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053972509.1	2	Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053973258.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053970710.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053977073.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053992592.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053989129.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053982665.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_053974036.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053988436.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053977370.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_053976351.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053994936.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053970865.1	7	KEGG: 00051+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Carbon fixation in photosynthetic organisms"
XP_053990040.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053986354.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053994247.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994985.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053993729.1	3	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_053990222.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_053975071.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053985098.1	4	MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119	"Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)"
XP_053989336.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053985881.1	27	Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-159236	"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053973219.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053979410.1	6	KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039	"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule"
XP_053992590.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-561;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-7254;KEGG: 00620+4.2.1.2	"Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle VII (acetate-producers)";"Pyruvate metabolism"
XP_053992473.1	40	Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-72165	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway"
XP_053983950.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053992815.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053986795.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_053974927.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053978581.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_053976296.1	6	MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_053991552.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053970388.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053991184.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053988152.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_053987063.1	7	KEGG: 00230+2.4.2.7;Reactome: R-HSA-74217;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-6798695;MetaCyc: PWY-6605;MetaCyc: PWY-6610	"Purine metabolism";"Purine salvage";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Neutrophil degranulation";"Adenine and adenosine salvage II";"Adenine salvage"
XP_053983826.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053994004.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053973366.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693616	"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053994316.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;MetaCyc: PWY-7382;Reactome: R-HSA-196780;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181	"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism"
XP_053990733.1	3	MetaCyc: PWY-7799;Reactome: R-HSA-2514859;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade";"Ac/N-end rule pathway"
XP_053977089.1	5	Reactome: R-HSA-9609523;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-5694530	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Cargo concentration in the ER"
XP_053972219.1	5	Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_053978788.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053974865.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053993815.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053977367.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_053980613.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_053986096.1	2	Reactome: R-HSA-163282;Reactome: R-HSA-2151201	"Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis"
XP_053976698.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053990201.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053983465.1	4	Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_053986671.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053990165.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_053985271.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_053983778.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053993830.1	4	Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053970979.1	5	KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20	"One carbon pool by folate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes"
XP_053977349.1	3	Reactome: R-HSA-4086400;Reactome: R-HSA-373080;Reactome: R-HSA-4608870	"PCP/CE pathway";"Class B/2 (Secretin family receptors)";"Asymmetric localization of PCP proteins"
XP_053990759.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053993252.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_053974426.1	11	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-171007	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Human papillomavirus infection";"Relaxin signaling pathway";"p38MAPK events"
XP_053988026.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_053982571.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053972957.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053971696.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053993689.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053988636.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_053978038.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053990380.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053981074.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-6992;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8	"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Fructose and mannose metabolism";"Mannitol degradation II";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053973598.1	13	Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662	"EPHA-mediated growth cone collapse";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"EPHB-mediated forward signaling"
XP_053974048.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053988448.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_053984920.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_053992830.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-171319;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"Telomere Extension By Telomerase";"HATs acetylate histones";"UCH proteinases"
XP_053979435.1	5	Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013	"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III"
XP_053977263.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_053972791.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053992673.1	1	KEGG: 00970+6.1.1.22	"Aminoacyl-tRNA biosynthesis"
XP_053982058.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053975261.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state"
XP_053985264.1	5	Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827	"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)"
XP_053988317.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_053975496.1	5	Reactome: R-HSA-8963693;KEGG: 00250+6.3.5.4;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-9648895	"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency"
XP_053989531.1	5	Reactome: R-HSA-212300;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"PRC2 methylates histones and DNA";"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_053980285.1	16	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-112382;Reactome: R-HSA-983168	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"Neddylation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053987377.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053986664.1	8	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053994863.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053976556.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-5357905	"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling"
XP_053976661.1	3	MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217	"Adenine and adenosine salvage VI";"Purine metabolism";"Purine salvage"
XP_053973846.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053992832.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053970735.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053974228.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053974345.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053990511.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053990079.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_053973656.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053987273.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-1799339	"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane"
XP_053984285.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-190873	"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"Gap junction degradation"
XP_053983058.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation"
XP_053993673.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-9608290;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Defective MUTYH substrate processing";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_053972768.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053971558.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053988213.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection"
XP_053971997.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis";"EGFR downregulation"
XP_053981061.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_053990718.1	10	KEGG: 00710+2.2.1.1;MetaCyc: PWY-6891;MetaCyc: PWY-6901;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;KEGG: 00030+2.2.1.1;MetaCyc: PWY-6892;MetaCyc: PWY-5723;MetaCyc: PWY-1861	"Carbon fixation in photosynthetic organisms";"Thiazole biosynthesis II (aerobic bacteria)";"Superpathway of glucose and xylose degradation";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Pentose phosphate pathway";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_053990948.1	52	Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053978602.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053975949.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053991277.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053986276.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053974007.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053988407.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053981143.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-983168;Reactome: R-HSA-9031525	"Protein ubiquitination";"VLDLR internalisation and degradation";"Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake"
XP_053975078.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053983695.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053986810.1	56	Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-4641258	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL"
XP_053970512.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053971291.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_053994924.1	2	Reactome: R-HSA-8853659;Reactome: R-HSA-5673001	"RET signaling";"RAF/MAP kinase cascade"
XP_053986595.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_053981294.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053985455.1	3	Reactome: R-HSA-204174;Reactome: R-HSA-8963684;Reactome: R-HSA-156590	"Regulation of pyruvate dehydrogenase (PDH) complex";"Tyrosine catabolism";"Glutathione conjugation"
XP_053978781.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation"
XP_053994606.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053977899.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053971466.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053991373.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053986812.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053975666.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053985554.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053970895.1	4	Reactome: R-HSA-4551295;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131	"Defective ALG11 causes ALG11-CDG (CDG-1p)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis"
XP_053982254.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053991072.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053970634.1	5	Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-6802946	"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"Signaling by moderate kinase activity BRAF mutants"
XP_053980631.1	17	KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;MetaCyc: PWY-4202;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-7179;Reactome: R-HSA-74217;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1	"Purine metabolism";"Guanosine nucleotides degradation III";"Arsenate detoxification I (mammalian)";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage V";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Purine catabolism";"Purine deoxyribonucleosides degradation I";"Purine salvage";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism"
XP_053981655.1	17	Reactome: R-HSA-2467813;KEGG: 04926+2.7.11.1;Reactome: R-HSA-68877;Reactome: R-HSA-141444;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-174178;KEGG: 05163+2.7.11.1;Reactome: R-HSA-4615885;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9022692;Reactome: R-HSA-9648025;KEGG: 04714+2.7.11.1	"Separation of Sister Chromatids";"Relaxin signaling pathway";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human cytomegalovirus infection";"SUMOylation of DNA replication proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Regulation of MECP2 expression and activity";"EML4 and NUDC in mitotic spindle formation";"Thermogenesis"
XP_053987093.1	1	KEGG: 00970+6.1.1.7	"Aminoacyl-tRNA biosynthesis"
XP_053978600.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053995067.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053975758.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053974634.1	19	Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8963888;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471	"Platelet sensitization by LDL";"LDL clearance";"Chylomicron assembly";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"LDL remodeling";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"VLDL assembly";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Chylomicron clearance";"Scavenging by Class B Receptors"
XP_053984631.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053989898.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053980021.1	18	MetaCyc: PWY-7383;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-561	"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_053981962.1	6	KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1	"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms"
XP_053973709.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_053989081.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053975375.1	13	MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5537	"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V"
XP_053987107.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_053985182.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053982775.1	2	Reactome: R-HSA-389661;Reactome: R-HSA-2408508	"Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se"
XP_053987077.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053992253.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_053970980.1	5	KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20	"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes"
XP_053977262.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation"
XP_053974045.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053994860.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053988445.1	2	Reactome: R-HSA-1483152;Reactome: R-HSA-1483115	"Hydrolysis of LPE";"Hydrolysis of LPC"
XP_053984486.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981095.1	5	Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-164843;Reactome: R-HSA-3270619	"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"2-LTR circle formation";"IRF3-mediated induction of type I IFN"
XP_053994168.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053990082.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053989048.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053977887.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-5674135	"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"MAP2K and MAPK activation"
XP_053994082.1	8	Reactome: R-HSA-163754;Reactome: R-HSA-71336;MetaCyc: PWY-5723;Reactome: R-HSA-6791462;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;MetaCyc: PWY-1861;Reactome: R-HSA-6791055	"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P"
XP_053986831.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_053972810.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_053985993.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053971364.1	10	Reactome: R-HSA-3000171;Reactome: R-HSA-975634;KEGG: 00230+3.5.2.17;MetaCyc: PWY-5691;MetaCyc: PWY-7849;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;Reactome: R-HSA-977225;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695	"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin III";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Amyloid fiber formation";"Retinoid cycle disease events";"Neutrophil degranulation"
XP_053980435.1	4	KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_053983775.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053980486.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053993253.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501	"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_053977229.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053976695.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053990379.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053980612.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_053983358.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_053992357.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053981824.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053993670.1	9	Reactome: R-HSA-110330;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-9608290;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Defective MUTYH substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_053988212.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053977049.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids"
XP_053979236.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_053990287.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053993833.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053990945.1	52	Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_053972494.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053989735.1	7	Reactome: R-HSA-446193;MetaCyc: PWY-6470;MetaCyc: PWY-5265;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis"
XP_053971555.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053988326.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053977067.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053983055.1	4	Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053984288.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053980726.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053975654.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_053980610.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053979969.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053982266.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053986709.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053993672.1	9	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-9608290;Reactome: R-HSA-110328;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Defective MUTYH substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_053987272.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_053983491.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053970738.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053974348.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_053977260.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053980288.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-8951664	"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Neddylation"
XP_053992833.1	2	Reactome: R-HSA-5678895;Reactome: R-HSA-382556	"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport"
XP_053984923.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053994862.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053979922.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_053982319.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_053988500.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053981398.1	5	Reactome: R-HSA-176407;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"T cell receptor signaling pathway";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053981807.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053981374.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_053975800.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053990080.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_053983409.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_053974324.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)"
XP_053981619.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053972096.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_053976137.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053993697.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-167200	"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_053984864.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053979241.1	2	Reactome: R-HSA-500753;Reactome: R-HSA-73621	"Pyrimidine biosynthesis";"Pyrimidine catabolism"
XP_053970513.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053970546.1	4	Reactome: R-HSA-3371568;Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497	"Attenuation phase";"ESR-mediated signaling";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053976571.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_053991956.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053986598.1	1	Reactome: R-HSA-427413	"NoRC negatively regulates rRNA expression"
XP_053973671.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053983674.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053989193.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053983698.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053975075.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053981142.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-179409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A"
XP_053994981.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053976355.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053991089.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053987181.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053978536.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053977184.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053987393.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053978603.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053981596.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053989007.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053976794.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_053992811.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053986791.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_053985885.1	6	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intra-Golgi traffic"
XP_053987909.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053975147.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053974307.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68952	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"DNA replication initiation"
XP_053981140.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174048;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176412;Reactome: R-HSA-174184	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_053985183.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053989510.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053971989.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053974081.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053982556.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053981848.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053991869.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980084.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053991370.1	5	Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6	"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism"
XP_053978707.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053979908.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_053991073.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_053981658.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053986768.1	20	MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7574;MetaCyc: PWY-7337	"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_053975122.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053984905.1	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_053986846.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053991847.1	7	MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2	"ATP biosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis"
XP_053994614.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053973664.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053970898.1	2	Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_053984281.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053987998.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053975056.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053977292.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053977971.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-390471	"Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053980344.1	2	Reactome: R-HSA-192456;Reactome: R-HSA-975634	"Digestion of dietary lipid";"Retinoid metabolism and transport"
XP_053987974.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984734.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-195253	"Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex"
XP_053988914.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053978911.1	6	Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958	"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease"
XP_053981065.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053970538.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_053980003.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053982498.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053980300.1	5	MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system"
XP_053985963.1	17	MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7176;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7205;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7221;MetaCyc: PWY-7198	"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_053989221.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053972565.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053980526.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053978403.1	8	MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-5789;MetaCyc: PWY-241	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type"
XP_053988334.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053978331.1	3	Reactome: R-HSA-3065678;Reactome: R-HSA-3065676;Reactome: R-HSA-983168	"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053971394.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_053974341.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053980734.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053971169.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053975101.1	3	Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_053984344.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053991975.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053983498.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_053985848.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_053984197.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053971755.1	9	Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome"
XP_053989586.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-1236974	"SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway"
XP_053973111.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus"
XP_053971075.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053991349.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053976826.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053970809.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053989041.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_053972464.1	3	Reactome: R-HSA-8936459;Reactome: R-HSA-383280;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines"
XP_053979999.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053989434.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053991367.1	5	MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Neutrophil degranulation"
XP_053978896.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053990414.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053981885.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053977964.1	6	Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-399997	"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion"
XP_053979207.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053986675.1	1	Reactome: R-HSA-77108	"Utilization of Ketone Bodies"
XP_053973464.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981179.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053990205.1	8	Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9639288	"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1"
XP_053991263.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis"
XP_053982114.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053982575.1	12	KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13	"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism"
XP_053975776.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_053971120.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053983296.1	7	MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_053981368.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053980302.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053991739.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050	"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053972066.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736	"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors"
XP_053984686.1	2	Reactome: R-HSA-5693571;Reactome: R-HSA-164843	"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation"
XP_053979413.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_053993667.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-9608290;Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-110330	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate processing";"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_053984170.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-5205685	"Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy"
XP_053973255.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053987267.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_053988488.1	5	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;Reactome: R-HSA-6798695	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Neutrophil degranulation"
XP_053986054.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053990340.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053973133.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_053974891.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053990016.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Gastrin-CREB signalling pathway via PKC and MAPK";"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053971800.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053978012.1	14	MetaCyc: PWY-8051;Reactome: R-HSA-1482788;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4	"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"alpha-Linolenic acid metabolism"
XP_053987882.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053983668.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053992667.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053993859.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053988855.1	2	Reactome: R-HSA-917729;Reactome: R-HSA-162588	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion"
XP_053980412.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053994043.1	2	Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_053975555.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053990730.1	7	Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390471	"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053995100.1	3	Reactome: R-HSA-70350;Reactome: R-HSA-9639288;Reactome: R-HSA-168928	"Fructose catabolism";"Amino acids regulate mTORC1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_053981651.1	3	MetaCyc: PWY-6700;MetaCyc: PWY-8106;Reactome: R-HSA-6782315	"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol"
XP_053989904.1	5	MetaCyc: PWY-5523;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-6168;MetaCyc: PWY-7863	"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis"
XP_053970617.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_053984025.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053978425.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053993112.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053978217.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_053981993.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053978785.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-390918	"Peroxisomal protein import";"Peroxisomal lipid metabolism"
XP_053979248.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053979325.1	5	MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism"
XP_053971295.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-1358803	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling"
XP_053993239.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053977125.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053984245.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053993763.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053974943.1	13	Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-937042;Reactome: R-HSA-937072;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5357956;Reactome: R-HSA-450302	"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"IRAK2 mediated activation of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"TNFR1-induced NFkappaB signaling pathway";"activated TAK1 mediates p38 MAPK activation"
XP_053993110.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053975821.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053974916.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_053973835.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053974385.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053992239.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053970713.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_053992472.1	40	Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-72163;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-6782135;Reactome: R-HSA-72203;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-73776	"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"Dual incision in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape"
XP_053973886.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_053977070.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053987188.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053984172.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053980328.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5689901	"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Metalloprotease DUBs"
XP_053980245.1	12	MetaCyc: PWY-6932;MetaCyc: PWY-5340;MetaCyc: PWY-5278;Reactome: R-HSA-2408550;KEGG: 00920+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00230+2.7.7.4;KEGG: 00920+2.7.7.4	"Selenate reduction";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfur metabolism";"Selenocompound metabolism";"Purine metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Purine metabolism";"Sulfur metabolism"
XP_053992818.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053989927.1	7	MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_053989388.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053985095.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053987029.1	4	MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14	"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism"
XP_053992110.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053971802.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053994327.1	5	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-165181	"Macroautophagy";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB"
XP_053994988.1	4	Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053991645.1	17	KEGG: 05235+3.1.3.16;Reactome: R-HSA-167200;Reactome: R-HSA-167287;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112382;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Formation of RNA Pol II elongation complex";"Th1 and Th2 cell differentiation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053976633.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053975155.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_053981623.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053980570.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053975917.1	12	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053991488.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053971259.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053982008.1	10	Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-111464;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111463;Reactome: R-HSA-611105;Reactome: R-HSA-9627069	"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs";"Respiratory electron transport";"Regulation of the apoptosome activity"
XP_053976418.1	21	MetaCyc: PWY-7205;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7221;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7187	"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II"
XP_053974562.1	7	MetaCyc: PWY-5921;Reactome: R-HSA-210500;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2	"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism"
XP_053985986.1	1	Reactome: R-HSA-446210	"Synthesis of UDP-N-acetyl-glucosamine"
XP_053985783.1	3	Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282	"HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B"
XP_053987421.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_053972606.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_053977424.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053973924.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_053992193.1	4	Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-8950505	"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_053992381.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053983921.1	3	KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053986379.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053985315.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053971508.1	7	Reactome: R-HSA-71336;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;KEGG: 00030+3.1.1.31;MetaCyc: PWY-8004;MetaCyc: PWY-5514	"Pentose phosphate pathway";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_053986860.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053978390.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053984493.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053978093.1	5	Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395	"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER"
XP_053993200.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053985059.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053992512.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053973606.1	16	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence"
XP_053993244.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053983008.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053979814.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053971176.1	4	MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones"
XP_053987588.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053992634.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_053990396.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_053975643.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053975720.1	4	MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2	"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism"
XP_053978392.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053993202.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA"
XP_053995139.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053985018.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_053973299.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053984806.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053986945.1	12	Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04150+2.7.11.1	"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Signaling by cytosolic FGFR1 fusion mutants";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"mTOR signaling pathway"
XP_053992510.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053993024.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_053976322.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053991235.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053986829.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_053994251.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053985423.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053976347.1	4	Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247	"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids"
XP_053976178.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053976194.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053986191.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053977231.1	4	KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557	"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism";"Selenocysteine synthesis"
XP_053974792.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053980572.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053971218.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053978124.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053988553.1	12	Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053971839.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053976459.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053982305.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053988899.1	3	Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_053980126.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"RHO GTPases activate PKNs"
XP_053976984.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053989253.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053971547.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053990598.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053981605.1	10	Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"Human papillomavirus infection";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Thermogenesis";"HATs acetylate histones";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053978840.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053987386.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053990957.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_053973083.1	6	Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8948751;Reactome: R-HSA-8863795	"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling"
XP_053985504.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053978148.1	7	MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism"
XP_053990115.1	4	Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-176974	"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Unwinding of DNA"
XP_053971569.1	3	Reactome: R-HSA-1660661;Reactome: R-HSA-9609523;Reactome: R-HSA-6798695	"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation"
XP_053975501.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery"
XP_053989186.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053984958.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053989135.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053988801.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription"
XP_053989449.1	6	MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_053980597.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053983240.1	4	KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_053973759.1	26	Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-9013695;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-381340	"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RORA activates gene expression";"Circadian Clock";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH4 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation"
XP_053980958.1	1	Reactome: R-HSA-8964572	"Lipid particle organization"
XP_053974689.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053982069.1	20	Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5656169	"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis"
XP_053993979.1	3	Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004	"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity"
XP_053992426.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053983204.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_053994957.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_053994598.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053989467.1	6	KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6118;MetaCyc: PWY-6952;MetaCyc: PWY-4261	"Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Glycerol degradation I"
XP_053977246.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_053972083.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053977937.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053989357.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_053980749.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053983242.1	2	Reactome: R-HSA-432720;Reactome: R-HSA-432722	"Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis"
XP_053979660.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053986530.1	24	Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-190840	"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Cilium Assembly";"Gap junction assembly";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_053988367.1	5	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053983323.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053972511.1	1	Reactome: R-HSA-420029	"Tight junction interactions"
XP_053973079.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053987628.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167161	"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation"
XP_053990561.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053988349.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053993345.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053982227.1	11	Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519	"RORA activates gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression"
XP_053971799.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053994656.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053982323.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_053994561.1	2	Reactome: R-HSA-426486;Reactome: R-HSA-203927	"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis"
XP_053990475.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053984767.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053972718.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053971306.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053978842.1	6	Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053972948.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053977685.1	10	Reactome: R-HSA-5607761;Reactome: R-HSA-5684264;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-983168;Reactome: R-HSA-5676590	"Dectin-1 mediated noncanonical NF-kB signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Neddylation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling"
XP_053983227.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053992345.1	14	Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397	"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER"
XP_053983630.1	3	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events"
XP_053988263.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053992228.1	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12	"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis"
XP_053989672.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053972863.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053984749.1	2	Reactome: R-HSA-5339700;Reactome: R-HSA-4641265	"TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes"
XP_053985405.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053983432.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053983279.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_053988956.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_053975799.1	2	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053987226.1	3	MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9	"Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism"
XP_053975306.1	4	MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I"
XP_053973220.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053979429.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053981196.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053978136.1	5	KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68;Reactome: R-HSA-975578	"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_053985011.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053990132.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053991528.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053975014.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053983615.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_053986890.1	2	Reactome: R-HSA-5689896;Reactome: R-HSA-936440	"Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling"
XP_053992626.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053994132.1	13	Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695	"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers"
XP_053986515.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053978360.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053970760.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_053982615.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053992904.1	5	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants"
XP_053986198.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_053972220.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_053972637.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979352.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053984772.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053986892.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_053973733.1	15	Reactome: R-HSA-5685938;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685939;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange"
XP_053973247.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053992712.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-446203	"SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation"
XP_053973985.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053994130.1	13	Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398	"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway"
XP_053973936.1	9	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053982430.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053987428.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983283.1	3	Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085	"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053980837.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_053974729.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053978362.1	19	MetaCyc: PWY-7227;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7187;Reactome: R-HSA-380320;MetaCyc: PWY-7226;Reactome: R-HSA-380270;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7221;MetaCyc: PWY-7184;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7197;MetaCyc: PWY-7224	"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Recruitment of NuMA to mitotic centrosomes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of mitotic centrosome proteins and complexes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage"
XP_053972343.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053979053.1	4	Reactome: R-HSA-186763;Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-428540	"Downstream signal transduction";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Activation of RAC1"
XP_053984770.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053988822.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053993388.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053987046.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817	"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis"
XP_053975547.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_053987310.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053978883.1	11	Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001	"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade"
XP_053974762.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_053972247.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053972733.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs"
XP_053989818.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_053983001.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053973222.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053975569.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053970729.1	7	Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053986205.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_053983928.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053983387.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_053992388.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053992927.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053990675.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_053994456.1	17	KEGG: 00020+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37	"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism"
XP_053990130.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053977436.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053976903.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053976706.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053974473.1	18	Reactome: R-HSA-5685938;Reactome: R-HSA-5689901;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;MetaCyc: PWY-7511;Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579	"HDR through Single Strand Annealing (SSA)";"Metalloprotease DUBs";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Protein ubiquitination";"HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange"
XP_053988073.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053991688.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981423.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053983900.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation"
XP_053986340.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053972195.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053976087.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053977624.1	2	Reactome: R-HSA-1660662;Reactome: R-HSA-1663150	"Glycosphingolipid metabolism";"The activation of arylsulfatases"
XP_053987621.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053973941.1	9	Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053985912.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053986877.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-7411;Reactome: R-HSA-1483166	"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA"
XP_053986304.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053973711.1	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA"
XP_053976301.1	6	KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920	"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)"
XP_053977906.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053971853.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053976433.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053980567.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053985727.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053990761.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053995153.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053994568.1	6	Reactome: R-HSA-8939211;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5693565	"ESR-mediated signaling";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053981779.1	16	Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-164939;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665	"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Gap junction degradation";"Formation of annular gap junctions";"MHC class II antigen presentation";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells"
XP_053987031.1	1	Reactome: R-HSA-73621	"Pyrimidine catabolism"
XP_053992586.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053971482.1	7	MetaCyc: PWY-7818;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;MetaCyc: PWY-7886	"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Choline biosynthesis I";"Synthesis of PC";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis"
XP_053986730.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053994054.1	11	Reactome: R-HSA-5693565;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-8940973;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-2029482	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"RUNX2 regulates osteoblast differentiation";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"Regulation of actin dynamics for phagocytic cup formation"
XP_053987400.1	58	Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-6798695;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689901;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949	"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Neutrophil degranulation";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Metalloprotease DUBs";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin"
XP_053984693.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_053971722.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053981315.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053994798.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053987545.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053985330.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053988397.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981059.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053985033.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053976849.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053975416.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053986988.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053975443.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053991326.1	18	Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695	"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events"
XP_053992434.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053986732.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053987402.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053983902.1	8	Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880	"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases"
XP_053986342.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053985704.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053971769.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053973208.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053975701.1	4	Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_053986223.1	12	MetaCyc: PWY-6708;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-5872;MetaCyc: PWY-7230;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60	"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_053971747.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053980951.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_053975259.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"DARPP-32 events";"PKA activation";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053988293.1	57	Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_053985623.1	57	Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880	"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases"
XP_053994177.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053972833.1	8	Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111458;Reactome: R-HSA-111464	"Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes"
XP_053974862.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053978935.1	17	Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-69473;Reactome: R-HSA-1834949;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548	"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"G2/M DNA damage checkpoint";"Cytosolic sensors of pathogen-associated DNA";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks"
XP_053980369.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053995108.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053994531.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053993765.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053991371.1	5	MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6;Reactome: R-HSA-6798695	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism";"Neutrophil degranulation"
XP_053980347.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-8873719;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148	"Neutrophil degranulation";"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053987554.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053984737.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053984216.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-8869496	"rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_053984243.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_053993159.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053989079.1	13	Reactome: R-HSA-110320;Reactome: R-HSA-6798695;Reactome: R-HSA-9646399;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-532668;Reactome: R-HSA-5358346;Reactome: R-HSA-5689896;Reactome: R-HSA-8876725;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-5689877	"Translesion Synthesis by POLH";"Neutrophil degranulation";"Aggrephagy";"ABC-family proteins mediated transport";"HSF1 activation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Hedgehog ligand biogenesis";"Ovarian tumor domain proteases";"Protein methylation";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Josephin domain DUBs"
XP_053980737.1	3	KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725;Reactome: R-HSA-2514859	"Lysine degradation";"Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053984347.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053983477.1	28	Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511	"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"HSF1 activation"
XP_053985107.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053980243.1	2	Reactome: R-HSA-5610787;Reactome: R-HSA-5620924	"Hedgehog 'off' state";"Intraflagellar transport"
XP_053984178.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053992812.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_053974383.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053986792.1	20	MetaCyc: PWY-7726;MetaCyc: PWY-6920;MetaCyc: PWY-7007;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-7606;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;MetaCyc: PWY-7288;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7337	"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)"
XP_053977375.1	10	KEGG: 00332+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41	"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism"
XP_053970945.1	7	KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-8964208	"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylketonuria";"Folate biosynthesis";"L-phenylalanine degradation V";"Phenylalanine metabolism"
XP_053984369.1	2	Reactome: R-HSA-8964038;Reactome: R-HSA-6798695	"LDL clearance";"Neutrophil degranulation"
XP_053990225.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053973672.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053979175.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053984459.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_053971397.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_053992765.1	11	MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-6992	"Mannitol degradation II";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation"
XP_053994982.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053988337.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053978779.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_053987180.1	1	Reactome: R-HSA-5601884	"PIWI-interacting RNA (piRNA) biogenesis"
XP_053973253.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053977078.1	10	MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-5667	"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I"
XP_053983629.1	4	Reactome: R-HSA-6799198;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-975871	"Complex I biogenesis";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"MyD88 cascade initiated on plasma membrane"
XP_053974082.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053984633.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation";"COPI-mediated anterograde transport"
XP_053979069.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053979415.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053993276.1	8	Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209	"TP53 Regulates Metabolic Genes";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation"
XP_053972449.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053977967.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053980023.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053984872.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053992118.1	10	KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6361	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)"
XP_053973670.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053983117.1	1	Reactome: R-HSA-2428928	"IRS-related events triggered by IGF1R"
XP_053972467.1	1	Reactome: R-HSA-9603798	"Class I peroxisomal membrane protein import"
XP_053984418.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_053978018.1	4	Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5912;MetaCyc: PWY-5041	"Methylation";"Cysteine and methionine metabolism";"2'-deoxymugineic acid phytosiderophore biosynthesis";"S-adenosyl-L-methionine cycle II"
XP_053994980.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053977719.1	6	KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6922	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_053979047.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053973186.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_053993595.1	19	Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-8876725;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-3214858	"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Protein methylation";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"RMTs methylate histone arginines"
XP_053988599.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053971539.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053982955.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053994045.1	4	Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553	"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_053992276.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_053976570.1	6	MetaCyc: PWY-7820;Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346	"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_053976493.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053980506.1	13	MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-561;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7254	"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle VII (acetate-producers)"
XP_053984023.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053973467.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053979204.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053980633.1	17	KEGG: 00760+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6611;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-5532;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6644;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-6620	"Nicotinate and nicotinamide metabolism";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage V";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Neutrophil degranulation";"Purine catabolism";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Guanine and guanosine salvage"
XP_053973357.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053986529.1	24	Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy"
XP_053984897.1	2	MetaCyc: PWY-7894;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes"
XP_053984308.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053988501.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053986057.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053985377.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053971073.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053990874.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053983490.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053990898.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053981329.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_053972996.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053972793.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053987264.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053977261.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053974614.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053993664.1	182	Reactome: R-HSA-5610783;Reactome: R-HSA-9033241;Reactome: R-HSA-8951664;Reactome: R-HSA-1236382;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-5689901;Reactome: R-HSA-5676590;Reactome: R-HSA-9645460;Reactome: R-HSA-4641263;Reactome: R-HSA-9646399;Reactome: R-HSA-8863795;Reactome: R-HSA-5205685;Reactome: R-HSA-9615710;Reactome: R-HSA-5689877;Reactome: R-HSA-5675221;Reactome: R-HSA-4641258;Reactome: R-HSA-69541;Reactome: R-HSA-180585;Reactome: R-HSA-3322077;Reactome: R-HSA-1295596;Reactome: R-HSA-3785653;Reactome: R-HSA-8948747;Reactome: R-HSA-6804760;Reactome: R-HSA-187577;Reactome: R-HSA-175474;Reactome: R-HSA-2565942;Reactome: R-HSA-975957;Reactome: R-HSA-68949;Reactome: R-HSA-110314;Reactome: R-HSA-2173791;Reactome: R-HSA-5357905;Reactome: R-HSA-9633012;Reactome: R-HSA-937072;Reactome: R-HSA-1358803;Reactome: R-HSA-912631;Reactome: R-HSA-4608870;Reactome: R-HSA-3769402;Reactome: R-HSA-1253288;Reactome: R-HSA-5689603;Reactome: R-HSA-156902;Reactome: R-HSA-4641257;Reactome: R-HSA-2559582;Reactome: R-HSA-2559585;Reactome: R-HSA-6782135;Reactome: R-HSA-8875360;Reactome: R-HSA-382556;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-2173796;Reactome: R-HSA-174178;Reactome: R-HSA-6781823;Reactome: R-HSA-6807004;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975110;Reactome: R-HSA-3134975;Reactome: R-HSA-5696400;Reactome: R-HSA-5687128;Reactome: R-HSA-179409;Reactome: R-HSA-2559580;Reactome: R-HSA-69017;Reactome: R-HSA-5654726;Reactome: R-HSA-6804756;Reactome: R-HSA-917729;Reactome: R-HSA-5607761;Reactome: R-HSA-174490;Reactome: R-HSA-5689896;Reactome: R-HSA-450302;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-8856825;Reactome: R-HSA-211733;Reactome: R-HSA-209560;Reactome: R-HSA-2467813;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-936440;Reactome: R-HSA-1234176;Reactome: R-HSA-168927;Reactome: R-HSA-8856828;Reactome: R-HSA-975144;Reactome: R-HSA-162588;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-2672351;Reactome: R-HSA-8849469;Reactome: R-HSA-937041;Reactome: R-HSA-5696394;Reactome: R-HSA-9613829;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-2122948;Reactome: R-HSA-8939902;Reactome: R-HSA-1799339;Reactome: R-HSA-5358346;Reactome: R-HSA-9637628;Reactome: R-HSA-2691232;Reactome: R-HSA-72764;Reactome: R-HSA-75815;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-5656121;Reactome: R-HSA-1169408;Reactome: R-HSA-8876493;Reactome: R-HSA-8866654;Reactome: R-HSA-937039;Reactome: R-HSA-977225;Reactome: R-HSA-9013507;Reactome: R-HSA-72649;Reactome: R-HSA-69231;Reactome: R-HSA-168928;Reactome: R-HSA-6783310;Reactome: R-HSA-2644606;Reactome: R-HSA-6781827;Reactome: R-HSA-5654727;Reactome: R-HSA-6804757;Reactome: R-HSA-936964;Reactome: R-HSA-72702;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5654732;Reactome: R-HSA-2979096;Reactome: R-HSA-5675482;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-2122947;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-8854050;Reactome: R-HSA-192823;Reactome: R-HSA-2173795;Reactome: R-HSA-9636383;Reactome: R-HSA-180534;Reactome: R-HSA-201681;Reactome: R-HSA-72706;Reactome: R-HSA-174084;Reactome: R-HSA-5696395;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-174048;Reactome: R-HSA-5693607;Reactome: R-HSA-5684264;Reactome: R-HSA-8866652;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5357956;Reactome: R-HSA-532668;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-450321;Reactome: R-HSA-209543;Reactome: R-HSA-9013973;Reactome: R-HSA-69601;Reactome: R-HSA-5655862;Reactome: R-HSA-5632684;Reactome: R-HSA-72695;Reactome: R-HSA-901032;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-5693565;Reactome: R-HSA-182971;Reactome: R-HSA-5696397;Reactome: R-HSA-174154;Reactome: R-HSA-917937;Reactome: R-HSA-6791226	"Degradation of GLI2 by the proteasome";"Peroxisomal protein import";"Neddylation";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activation of NF-kappaB in B cells";"Circadian Clock";"Metalloprotease DUBs";"NIK-->noncanonical NF-kB signaling";"Alpha-protein kinase 1 signaling pathway";"Regulation of FZD by ubiquitination";"Aggrephagy";"Downregulation of ERBB2 signaling";"Pink/Parkin Mediated Mitophagy";"Late endosomal microautophagy";"Josephin domain DUBs";"Negative regulation of MAPK pathway";"Degradation of DVL";"Stabilization of p53";"Vif-mediated degradation of APOBEC3G";"Glycogen synthesis";"Spry regulation of FGF signaling";"Myoclonic epilepsy of Lafora";"Regulation of PTEN localization";"Regulation of TP53 Activity through Methylation";"SCF(Skp2)-mediated degradation of p27/p21";"Assembly Of The HIV Virion";"Regulation of PLK1 Activity at G2/M Transition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Orc1 removal from chromatin";"Recognition of DNA damage by PCNA-containing replication complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of TNFR1 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of signaling by CBL";"Asymmetric localization of PCP proteins";"Deactivation of the beta-catenin transactivating complex";"Downregulation of ERBB4 signaling";"UCH proteinases";"Peptide chain elongation";"Degradation of AXIN";"Senescence-Associated Secretory Phenotype (SASP)";"Oncogene Induced Senescence";"Dual incision in TC-NER";"InlB-mediated entry of Listeria monocytogenes into host cell";"ABC-family proteins mediated transport";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of MET activity";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of innate immune responses to cytosolic DNA";"Dual Incision in GG-NER";"MAPK6/MAPK4 signaling";"APC-Cdc20 mediated degradation of Nek2A";"Oxidative Stress Induced Senescence";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of FGFR1 signaling";"Regulation of TP53 Activity through Phosphorylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Dectin-1 mediated noncanonical NF-kB signaling";"Membrane binding and targetting of GAG proteins";"Ovarian tumor domain proteases";"activated TAK1 mediates p38 MAPK activation";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Cargo recognition for clathrin-mediated endocytosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"NF-kB is activated and signals survival";"Separation of Sister Chromatids";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulators of DDX58/IFIH1 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TICAM1, RIP1-mediated IKK complex recruitment";"Clathrin-mediated endocytosis";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Budding and maturation of HIV virion";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Stimuli-sensing channels";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IKK complex recruitment mediated by RIP1";"DNA Damage Recognition in GG-NER";"Chaperone Mediated Autophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated NOTCH1 Transmits Signal to the Nucleus";"Regulation of RUNX2 expression and activity";"SRP-dependent cotranslational protein targeting to membrane";"Hedgehog ligand biogenesis";"Modulation by Mtb of host immune system";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Eukaryotic Translation Termination";"Ubiquitin-dependent degradation of Cyclin D";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"Translesion synthesis by POLI";"ISG15 antiviral mechanism";"InlA-mediated entry of Listeria monocytogenes into host cells";"E3 ubiquitin ligases ubiquitinate target proteins";"IRAK1 recruits IKK complex";"Amyloid fiber formation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Translation initiation complex formation";"Cyclin D associated events in G1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fanconi Anemia Pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Negative regulation of FGFR2 signaling";"Regulation of TP53 Degradation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Ribosomal scanning and start codon recognition";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Negative regulation of FGFR3 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of necroptotic cell death";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Viral mRNA Translation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Prevention of phagosomal-lysosomal fusion";"Vpu mediated degradation of CD4";"TCF dependent signaling in response to WNT";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Autodegradation of Cdh1 by Cdh1:APC/C";"Formation of Incision Complex in GG-NER";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"APC/C:Cdc20 mediated degradation of Cyclin B";"Processing of DNA double-strand break ends";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"TNFR1-induced NFkappaB signaling pathway";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"p75NTR recruits signalling complexes";"TICAM1-dependent activation of IRF3/IRF7";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by POLK";"Hedgehog 'on' state";"Formation of the ternary complex, and subsequently, the 43S complex";"ER Quality Control Compartment (ERQC)";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"EGFR downregulation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APC/C:Cdc20 mediated degradation of Securin";"Iron uptake and transport";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053980611.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism"
XP_053970614.1	9	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation"
XP_053995147.1	1	Reactome: R-HSA-9616222	"Transcriptional regulation of granulopoiesis"
XP_053994307.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053986673.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053971822.1	9	Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053985273.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_053994081.1	8	Reactome: R-HSA-6791055;Reactome: R-HSA-163754;Reactome: R-HSA-71336;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462	"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P"
XP_053976919.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053980308.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053982573.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053981362.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053993671.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-9608290;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222	"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate processing";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding"
XP_053985827.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-168138	"Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade"
XP_053987992.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_053987271.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_053988211.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053986830.1	2	Reactome: R-HSA-3928665;Reactome: R-HSA-2682334	"EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling"
XP_053978214.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_053981063.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053976597.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053979921.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex"
XP_053989924.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053992096.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053990192.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772	"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape"
XP_053978542.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053983492.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053971753.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053982589.1	4	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_053976663.1	8	Reactome: R-HSA-3928665;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856825	"EPH-ephrin mediated repulsion of cells";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis"
XP_053994861.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053976126.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053970981.1	5	KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.20	"One carbon pool by folate";"Folate transformations I";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes"
XP_053980706.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053992111.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053993354.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_053991828.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053977884.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053988014.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676	"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_053984411.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053978011.1	14	KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;Reactome: R-HSA-975634;MetaCyc: PWY-7409;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4	"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Ether lipid metabolism"
XP_053988799.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling"
XP_053989559.1	5	Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_053980164.1	15	Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-112382	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex"
XP_053994809.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053977696.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053989208.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053990809.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-8951664	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Neddylation"
XP_053975089.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053981652.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_053993111.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053975820.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053977519.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053981827.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053980411.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053978579.1	5	KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_053971457.1	1	Reactome: R-HSA-140342	"Apoptosis induced DNA fragmentation"
XP_053992795.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053971367.1	10	Reactome: R-HSA-2453902;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;Reactome: R-HSA-6798695;MetaCyc: PWY-7394;Reactome: R-HSA-977225	"The canonical retinoid cycle in rods (twilight vision)";"Purine metabolism";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Neutrophil degranulation";"Urate conversion to allantoin II";"Amyloid fiber formation"
XP_053975657.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053977064.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053986146.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053979714.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053989711.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053979944.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053980537.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-264870;Reactome: R-HSA-6794361	"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins"
XP_053990731.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6798695;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957	"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Neutrophil degranulation";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053970515.1	10	MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2206292;KEGG: 00052+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2024096	"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"MPS VII - Sly syndrome";"Galactose metabolism";"Other glycan degradation";"HS-GAG degradation"
XP_053991169.1	29	Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73762	"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation"
XP_053972497.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053989406.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053995056.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_053976353.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053990341.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053981148.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053988569.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events"
XP_053993565.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053975073.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053981377.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053989195.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053977751.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053994284.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-8869496	"Mitochondrial protein import";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"
XP_053975869.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053971801.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053988547.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444	"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053985883.1	6	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"VxPx cargo-targeting to cilium"
XP_053977209.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053978605.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053991122.1	4	Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250	"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis"
XP_053984171.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053974174.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-5218921	"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"Downstream signal transduction";"VEGFR2 mediated cell proliferation"
XP_053985329.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053977356.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053971121.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053975539.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053988218.1	8	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053982789.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053989733.1	3	MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574	"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway"
XP_053990943.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050	"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053986954.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053972239.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053993886.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053990713.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053991576.1	4	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053990868.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053974327.1	4	Reactome: R-HSA-446193;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis"
XP_053977972.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053970342.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053993694.1	14	Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053987294.1	8	KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16	"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053976134.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053972966.1	3	MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053983053.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_053984925.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053979430.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_053977187.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053974342.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053975102.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_053992886.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053987960.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053994868.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053980849.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_053982350.1	6	Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Lysosome Vesicle Biogenesis"
XP_053973763.1	26	Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847;Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-210744;Reactome: R-HSA-3899300	"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones";"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Circadian Clock";"RORA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors"
XP_053979928.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053994746.1	2	KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895	"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism"
XP_053994943.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053973110.1	5	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-6784531	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus"
XP_053983677.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053989343.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053978332.1	3	Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168	"SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053989040.1	3	Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571	"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)"
XP_053988443.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053974043.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053988416.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053974016.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053979432.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053974340.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053982976.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053976549.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"Cargo concentration in the ER"
XP_053990129.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053982773.1	18	KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925	"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG"
XP_053980280.1	6	Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053983429.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053978033.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053981093.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571	"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)"
XP_053975808.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053975397.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-380095	"G alpha (q) signalling events";"Tachykinin receptors bind tachykinins"
XP_053972649.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053994617.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053973667.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053988259.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053983976.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_053980433.1	4	MetaCyc: PWY-7807;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805	"Glyphosate degradation III";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation"
XP_053970304.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053985995.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053991108.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053987929.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053970877.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053984280.1	10	MetaCyc: PWY-5839;MetaCyc: PWY-5891;MetaCyc: PWY-7996;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5844;MetaCyc: PWY-5892;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5895	"Menaquinol-7 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-12 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-13 biosynthesis"
XP_053994129.1	13	Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-139853	"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels"
XP_053973649.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053980087.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053980618.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053977970.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053994891.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053982429.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053985035.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053994792.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053988802.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_053982908.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053991839.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053994560.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982021.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053975445.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053975876.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053983908.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053970709.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053986225.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053986177.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053990560.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053989664.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053979556.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_053979661.1	4	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events"
XP_053981933.1	1	Reactome: R-HSA-1483255	"PI Metabolism"
XP_053985625.1	57	Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895	"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis"
XP_053993299.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053988654.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053979409.1	6	Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107	"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system"
XP_053972193.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053976612.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053990562.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053980695.1	9	Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082	"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression"
XP_053981425.1	7	Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-180746	"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein"
XP_053985918.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053973244.1	2	KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation"
XP_053971855.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053985748.1	9	MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5789;Reactome: R-HSA-1475029;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1	"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Reversible hydration of carbon dioxide";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism"
XP_053983241.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053975212.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053991443.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_053986417.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053980834.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053987206.1	6	MetaCyc: PWY-4381;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5743;MetaCyc: PWY-6722	"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Candicidin biosynthesis"
XP_053984834.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053995155.1	6	Reactome: R-HSA-6807878;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-416993	"COPI-mediated anterograde transport";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors"
XP_053992924.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979674.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053994790.1	57	Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323	"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling"
XP_053991701.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053988800.1	7	Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-165159	"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"Amino acids regulate mTORC1";"mTOR signalling"
XP_053985338.1	1	Reactome: R-HSA-8874211	"CREB3 factors activate genes"
XP_053971645.1	5	Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656253;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)"
XP_053994562.1	2	Reactome: R-HSA-203927;Reactome: R-HSA-426486	"MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis"
XP_053984695.1	5	MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_053988108.1	5	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis"
XP_053992533.1	16	Reactome: R-HSA-6811558;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-512988;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-114604	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Interleukin-7 signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PIP3 activates AKT signaling";"Rho GTPase cycle";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"RET signaling";"Interleukin receptor SHC signaling";"GPVI-mediated activation cascade"
XP_053971488.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053982241.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053983717.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053991306.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053983947.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053992948.1	8	Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411	"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere"
XP_053994673.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053988120.1	10	Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-445144	"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Neutrophil degranulation";"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1"
XP_053984058.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053983285.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_053987422.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-166166	"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade"
XP_053970846.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053973983.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053983969.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053971702.1	6	MetaCyc: PWY-6606;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608	"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Guanosine nucleotides degradation III"
XP_053994250.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053978179.1	7	Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232	"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_053972345.1	2	Reactome: R-HSA-427413;Reactome: R-HSA-3214847	"NoRC negatively regulates rRNA expression";"HATs acetylate histones"
XP_053986190.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053977230.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053992863.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053985603.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053972735.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985536.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053992511.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053989812.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053974768.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053982236.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053978836.1	5	Reactome: R-HSA-111469;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111463	"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs"
XP_053993948.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053994057.1	11	Reactome: R-HSA-2029482;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;KEGG: 04660+2.7.10.2;Reactome: R-HSA-983231;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-69231;Reactome: R-HSA-525793;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565	"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"T cell receptor signaling pathway";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"Cyclin D associated events in G1";"Myogenesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053988075.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053989159.1	3	Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395	"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER"
XP_053993079.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053985724.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053973228.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_053980564.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053993863.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053991520.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053986203.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053986324.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053980778.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053988169.1	9	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-442982	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Long-term potentiation";"EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor"
XP_053977926.1	7	Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885	"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins"
XP_053984137.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation"
XP_053989595.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053980355.1	4	Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_053983646.1	5	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_053986861.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053980465.1	2	KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053991522.1	13	MetaCyc: PWY-5537;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913	"Pyruvate fermentation to acetate V";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)"
XP_053974574.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053978391.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053974598.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053978183.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053992759.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_053971914.1	6	MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84	"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis"
XP_053970598.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053981741.1	3	KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3	"Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis"
XP_053977158.1	1	Reactome: R-HSA-8851805	"MET activates RAS signaling"
XP_053987420.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_053993437.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053990689.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053980137.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_053973426.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053985707.1	7	Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628	"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3"
XP_053971700.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994252.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053982646.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-5663220	"Signaling by ROBO receptors";"RHO GTPases Activate Formins"
XP_053977232.1	4	Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2	"Selenocysteine synthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_053982613.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053994762.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053973712.1	5	Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_053983325.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621	"Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism"
XP_053976302.1	6	Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578	"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway"
XP_053975700.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053993343.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_053994473.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053993222.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053991501.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053988056.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053970456.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053988101.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053978104.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053989835.1	7	Reactome: R-HSA-611105;MetaCyc: PWY-5083;MetaCyc: PWY-3781;Reactome: R-HSA-6799198;MetaCyc: PWY-4302;KEGG: 00190+7.1.1.2;MetaCyc: PWY-6692	"Respiratory electron transport";"NAD/NADH phosphorylation and dephosphorylation";"Aerobic respiration I (cytochrome c)";"Complex I biogenesis";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Fe(II) oxidation"
XP_053987647.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053982248.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053970366.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053990473.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_053990815.1	19	Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-428543;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-5625970;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-182971;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467	"Rho GTPase cycle";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"Inactivation of CDC42 and RAC1";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"RHO GTPases activate KTN1";"Myogenesis";"CD28 dependent Vav1 pathway";"EGFR downregulation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs"
XP_053978848.1	2	Reactome: R-HSA-389397;Reactome: R-HSA-416476	"Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events"
XP_053993936.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053972942.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053983173.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053989694.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053972865.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053980826.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053985331.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760	"PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation"
XP_053990762.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053992316.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053974219.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053992343.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053975334.1	12	Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-450408	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"AUF1 (hnRNP D0) binds and destabilizes mRNA"
XP_053988265.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053987030.1	4	Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14	"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism"
XP_053979756.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_053983413.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053981603.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053977404.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053990592.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053986731.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053989255.1	33	Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins"
XP_053972940.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053985896.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053989133.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_053981724.1	6	Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-114516	"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation"
XP_053990113.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053990146.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053984952.1	5	Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409	"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation"
XP_053990760.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053974258.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053973085.1	6	Reactome: R-HSA-2173788;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-8948751	"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity"
XP_053994760.1	15	Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519	"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression"
XP_053973710.1	4	Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37	"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism"
XP_053976300.1	6	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)"
XP_053973940.1	9	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053982446.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053977787.1	57	Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084	"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_053972036.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053986341.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053976344.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053975702.1	1	KEGG: 04660+2.7.10.2	"T cell receptor signaling pathway"
XP_053971528.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053995014.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_053972085.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053983901.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation"
XP_053982638.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_053993637.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"
XP_053987743.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053987620.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053976197.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053980376.1	10	Reactome: R-HSA-4719377;MetaCyc: PWY-7921;Reactome: R-HSA-913709;Reactome: R-HSA-4719360;MetaCyc: PWY-7661;Reactome: R-HSA-4717374;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83;MetaCyc: PWY-7922;Reactome: R-HSA-162699	"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation of mucins";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Synthesis of dolichyl-phosphate mannose"
XP_053987582.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression"
XP_053991155.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053978807.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_053978398.1	12	KEGG: 00500+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7343;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;MetaCyc: PWY-7238	"Starch and sucrose metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Sucrose biosynthesis II"
XP_053981338.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053985012.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053988371.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053993208.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053982207.1	57	Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276	"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint"
XP_053976987.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053976328.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-3371571	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"HSF1-dependent transactivation"
XP_053971544.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053970774.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053983999.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_053990577.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053986713.1	19	Reactome: R-HSA-194840;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-5663220;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-428543;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-5625970;Reactome: R-HSA-182971;Reactome: R-HSA-3928662;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467	"Rho GTPase cycle";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Inactivation of CDC42 and RAC1";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"RHO GTPases activate KTN1";"EGFR downregulation";"EPHB-mediated forward signaling";"Myogenesis";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs"
XP_053991233.1	5	Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135	"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER"
XP_053986943.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053983000.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053986385.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210	"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053983207.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_053994577.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053992208.1	5	Reactome: R-HSA-75109;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;KEGG: 00073+2.3.1.20	"Triglyceride biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Cutin, suberine and wax biosynthesis"
XP_053982044.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Generic Transcription Pathway";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053994954.1	3	KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217	"Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage"
XP_053986336.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053984771.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053979351.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053987499.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053989354.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_053985425.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053971212.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053982303.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053979296.1	6	Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053991480.1	1	KEGG: 00900+3.4.24.84	"Terpenoid backbone biosynthesis"
XP_053994131.1	13	Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-114508;Reactome: R-HSA-1489509	"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling"
XP_053980578.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053981918.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053980594.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053977523.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053988555.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_053982431.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053970761.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_053980764.1	1	Reactome: R-HSA-382556	"ABC-family proteins mediated transport"
XP_053976635.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053975153.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053991616.1	56	Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257	"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN"
XP_053991643.1	17	Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167290;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112382;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167287	"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Th1 and Th2 cell differentiation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"T cell receptor signaling pathway";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"HIV elongation arrest and recovery"
XP_053988821.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053972221.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_053993406.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053971210.1	5	Reactome: R-HSA-9630222;Reactome: R-HSA-9630221;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329	"Defective NTHL1 substrate binding";"Defective NTHL1 substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine"
XP_053986891.1	2	Reactome: R-HSA-936440;Reactome: R-HSA-5689896	"Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases"
XP_053980106.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053972535.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053985217.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_053988364.1	12	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053975235.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982517.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_053993518.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_053981625.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053981086.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053973221.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053971502.1	17	Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400	"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER"
XP_053984106.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053985346.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_053992195.1	8	KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980	"Oxidative phosphorylation";"Ion channel transport";"Insulin receptor recycling";"Photosynthesis";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis"
XP_053992518.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053979498.1	5	KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_053979474.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053976025.1	5	KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73614	"Pyrimidine metabolism";"Pyrimidine catabolism";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine salvage"
XP_053984764.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053972868.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053984817.1	52	Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258	"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL"
XP_053989130.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053985402.1	4	Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1	"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Glycine, serine and threonine metabolism"
XP_053983172.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053990763.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053977416.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053984076.1	12	Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_053982245.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053981600.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053983410.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053978845.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_053975607.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053987033.1	3	Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658	"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_053972943.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053985545.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053990239.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903	"Neutrophil degranulation";"Synthesis of PC";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy"
XP_053990472.1	1	Reactome: R-HSA-379726	"Mitochondrial tRNA aminoacylation"
XP_053972713.1	2	KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085	"Starch and sucrose metabolism";"Digestion of dietary carbohydrate"
XP_053993732.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053994239.1	17	MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-200425;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2	"Candicidin biosynthesis";"Fatty acid biosynthesis";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate cycle";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carnitine metabolism";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Pyruvate metabolism"
XP_053971424.1	14	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053993342.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-983168	"Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053970678.1	12	Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_053987910.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053982172.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053980076.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053987740.1	56	Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974	"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway"
XP_053993223.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053976303.1	6	MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143	"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis"
XP_053988970.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053973746.1	9	Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253	"HS-GAG biosynthesis";"HS-GAG degradation";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS"
XP_053973713.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_053989456.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053976999.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_053971851.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053981854.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053983987.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053983328.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053980817.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053987704.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053982410.1	10	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04660+2.7.10.2;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"mTOR signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"T cell receptor signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053994470.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053975906.1	1	Reactome: R-HSA-5689901	"Metalloprotease DUBs"
XP_053989509.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-388479	"G alpha (q) signalling events";"Vasopressin-like receptors"
XP_053977839.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053988466.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053975703.1	2	KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)"
XP_053976224.1	5	MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053971525.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053986221.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053984668.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_053988356.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053972617.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053987742.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053980953.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053993304.1	56	Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053988972.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053978294.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053975624.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053980756.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053981781.1	2	Reactome: R-HSA-2514853;Reactome: R-HSA-2299718	"Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes"
XP_053990667.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053978143.1	4	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)"
XP_053978116.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053989132.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053988187.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053992340.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053985031.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs"
XP_053975441.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053983412.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982025.1	2	MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16	"Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053981588.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053983878.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053992877.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68949	"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin"
XP_053984351.1	3	Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508	"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis"
XP_053988558.1	12	Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy"
XP_053988997.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053978061.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053984461.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053977522.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053991604.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053981915.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053975150.1	5	MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_053985428.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053981157.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053984296.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053986927.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053991640.1	11	Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210	"DNA replication initiation";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053991723.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053992205.1	6	KEGG: 00230+2.4.2.8;MetaCyc: PWY-6610;MetaCyc: PWY-6599;MetaCyc: PWY-6620;MetaCyc: PWY-6609;KEGG: 00983+2.4.2.8	"Purine metabolism";"Adenine salvage";"Guanine and guanosine salvage II";"Guanine and guanosine salvage";"Adenine and adenosine salvage III";"Drug metabolism - other enzymes"
XP_053975436.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053978754.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053991850.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053975485.1	13	MetaCyc: PWY-5122;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7102;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7141;MetaCyc: PWY-7721	"Geranyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis"
XP_053986942.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053983302.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-7214	"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_053984114.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053991479.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053976325.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053986712.1	19	Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"Myogenesis";"EGFR downregulation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"Rho GTPase cycle";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_053972809.1	1	KEGG: 00240+3.1.3.89	"Pyrimidine metabolism"
XP_053978395.1	12	MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-7343;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077	"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Stachyose degradation";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis"
XP_053975648.1	3	Reactome: R-HSA-5626978;Reactome: R-HSA-193681;Reactome: R-HSA-1660662	"TNFR1-mediated ceramide production";"Ceramide signalling";"Glycosphingolipid metabolism"
XP_053984575.1	2	Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053993205.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053988209.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053981335.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_053970464.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053987605.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053987583.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053991158.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053980351.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053986865.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_053970354.1	2	KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384	"Pentose phosphate pathway";"Ethanol oxidation"
XP_053985310.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053972284.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium"
XP_053977014.1	2	Reactome: R-HSA-446193;Reactome: R-HSA-4570571	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)"
XP_053980609.1	5	MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)"
XP_053982281.1	30	Reactome: R-HSA-1358803;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-111447;Reactome: R-HSA-5218920;Reactome: R-HSA-6804757;Reactome: R-HSA-211163;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389513;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804758;Reactome: R-HSA-8876198;Reactome: R-HSA-69656;Reactome: R-HSA-6804759;Reactome: R-HSA-389357;Reactome: R-HSA-198693;Reactome: R-HSA-9634638;Reactome: R-HSA-5628897;Reactome: R-HSA-69202;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8948751;Reactome: R-HSA-8941332;Reactome: R-HSA-199418;Reactome: R-HSA-9614399;Reactome: R-HSA-198323;Reactome: R-HSA-5674400	"Downregulation of ERBB2:ERBB3 signaling";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Activation of BAD and translocation to mitochondria";"VEGFR2 mediated vascular permeability";"Regulation of TP53 Degradation";"AKT-mediated inactivation of FOXO1A";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"CTLA4 inhibitory signaling";"Relaxin signaling pathway";"Regulation of TP53 Activity through Acetylation";"RAB GEFs exchange GTP for GDP on RABs";"Cyclin A:Cdk2-associated events at S phase entry";"Regulation of TP53 Activity through Association with Co-factors";"CD28 dependent PI3K/Akt signaling";"AKT phosphorylates targets in the nucleus";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"TP53 Regulates Metabolic Genes";"Cyclin E associated events during G1/S transition";"PI3K-Akt signaling pathway";"Regulation of PTEN stability and activity";"RUNX2 regulates genes involved in cell migration";"Negative regulation of the PI3K/AKT network";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer"
XP_053986940.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053992515.1	7	KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6352	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Glycerophospholipid metabolism";"3-phosphoinositide biosynthesis"
XP_053982734.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053983300.1	7	MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214	"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)"
XP_053986626.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723	"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation"
XP_053986710.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053990497.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053992174.1	13	MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1	"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_053971685.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6606;MetaCyc: PWY-5497	"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)"
XP_053983197.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053979764.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053977306.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053976189.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-6814122	"BBSome-mediated cargo-targeting to cilium";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053986904.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053988071.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053985312.1	6	Reactome: R-HSA-3878781;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-7900	"Glycogen storage disease type IV (GBE1)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)"
XP_053978074.1	10	Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053970471.1	2	Reactome: R-HSA-1433559;Reactome: R-HSA-8951664	"Regulation of KIT signaling";"Neddylation"
XP_053993890.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053973284.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053976413.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053977520.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053986085.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-1799339	"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053975152.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_053972341.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053989054.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053991642.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053993198.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_053982197.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053982871.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053985628.1	57	Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895	"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis"
XP_053988274.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053972307.1	7	Reactome: R-HSA-1483166;Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;KEGG: 00564+3.1.4.4;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;MetaCyc: PWY-3561	"Synthesis of PA";"Role of phospholipids in phagocytosis";"Synthesis of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Choline biosynthesis III"
XP_053975026.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_053990996.1	6	Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway"
XP_053990793.1	4	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053983905.1	8	Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of PTEN localization";"Regulation of TP53 Degradation"
XP_053986345.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053972190.1	3	Reactome: R-HSA-8874081;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171	"MET activates PTK2 signaling";"Laminin interactions";"Non-integrin membrane-ECM interactions"
XP_053986735.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053987405.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-186763	"MET activates RAP1 and RAC1";"Regulation of signaling by CBL";"MET receptor recycling";"Downstream signal transduction"
XP_053971584.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053987196.1	6	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;MetaCyc: PWY-5514	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_053975636.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_053994793.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053982905.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053973081.1	6	Reactome: R-HSA-8863795;Reactome: R-HSA-8948751;Reactome: R-HSA-2173788;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;MetaCyc: PWY-7511	"Downregulation of ERBB2 signaling";"Regulation of PTEN stability and activity";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Protein ubiquitination"
XP_053992614.1	3	Reactome: R-HSA-71336;KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44	"Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway"
XP_053973190.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes"
XP_053981312.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053987542.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_053971485.1	3	Reactome: R-HSA-6804115;Reactome: R-HSA-5617472;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deadenylation of mRNA"
XP_053990811.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053988496.1	16	Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053972324.1	30	Reactome: R-HSA-8939902;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-5610783;Reactome: R-HSA-2565942;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-9604323;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-187577;Reactome: R-HSA-2644607;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-2894862;Reactome: R-HSA-5607764;Reactome: R-HSA-69231	"Regulation of RUNX2 expression and activity";"Circadian Clock";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Degradation of GLI2 by the proteasome";"Regulation of PLK1 Activity at G2/M Transition";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of NOTCH4 signaling";"Iron uptake and transport";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SCF(Skp2)-mediated degradation of p27/p21";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1"
XP_053973546.1	3	Reactome: R-HSA-5689603;Reactome: R-HSA-2151201;Reactome: R-HSA-3214847	"UCH proteinases";"Transcriptional activation of mitochondrial biogenesis";"HATs acetylate histones"
XP_053971436.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053994563.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053979834.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053988105.1	5	MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24	"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism"
XP_053993109.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053984698.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053984674.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053987504.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053988261.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053981310.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053990697.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053975317.1	4	Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-8953750	"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6"
XP_053975213.1	15	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks"
XP_053992109.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053975937.1	1	Reactome: R-HSA-390651	"Dopamine receptors"
XP_053985915.1	11	Reactome: R-HSA-193692;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802	"Regulated proteolysis of p75NTR";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3"
XP_053977708.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053992981.1	3	Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5	"Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_053973324.1	1	KEGG: 00010+5.1.3.15	"Glycolysis / Gluconeogenesis"
XP_053976438.1	2	Reactome: R-HSA-9610379;Reactome: R-HSA-917729	"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053980674.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053991505.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053971150.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_053994811.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053993862.1	4	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_053989768.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_053973177.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053978180.1	7	Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2691232	"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_053973225.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053973348.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053988078.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053986202.1	5	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling"
XP_053992829.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_053987779.1	5	Reactome: R-HSA-350054;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-1912420;Reactome: R-HSA-5083630	"Notch-HLH transcription pathway";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3"
XP_053978091.1	5	Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310	"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Fanconi Anemia Pathway"
XP_053984939.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053974765.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053983534.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_053993945.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053993287.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053987018.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053985602.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053989475.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053989813.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053993829.1	7	Reactome: R-HSA-1855204;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_053979564.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053986634.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053993191.1	2	Reactome: R-HSA-162588;Reactome: R-HSA-917729	"Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053979058.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053970765.1	11	Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053981621.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053994672.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053975231.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053985234.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053973982.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053992715.1	7	Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5358346;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Hedgehog ligand biogenesis";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Activation of SMO"
XP_053987423.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053984055.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053994253.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053987935.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053979355.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053991314.1	18	Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of the Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_053983149.1	10	MetaCyc: PWY-5030;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-6613;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;MetaCyc: PWY-5497	"L-histidine degradation III";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)"
XP_053977233.1	4	MetaCyc: PWY-6281;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00450+2.9.1.2	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"Selenocompound metabolism"
XP_053979019.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982612.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_053982435.1	3	KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2	"Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation"
XP_053994670.1	4	Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053983167.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053982486.1	2	Reactome: R-HSA-382556;Reactome: R-HSA-5678895	"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis"
XP_053988551.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_053994186.1	4	KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931	"Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis"
XP_053973980.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053977769.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053970810.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053972417.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids"
XP_053986512.1	2	Reactome: R-HSA-375280;Reactome: R-HSA-416476	"Amine ligand-binding receptors";"G alpha (q) signalling events"
XP_053984468.1	13	MetaCyc: PWY-1722;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;KEGG: 00670+1.5.1.5+3.5.4.9	"Formate assimilation into 5,10-methylenetetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations II (plants)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"One carbon pool by folate"
XP_053993860.1	5	Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_053980468.1	1	Reactome: R-HSA-5223345	"Miscellaneous transport and binding events"
XP_053977480.1	1	Reactome: R-HSA-446203	"Asparagine N-linked glycosylation"
XP_053975641.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053978182.1	7	Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096	"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_053986200.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798	"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import"
XP_053980358.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053982149.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_053991523.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053971607.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053973417.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053982167.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053983435.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053990253.1	9	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-110314;Reactome: R-HSA-6782135	"DNA Damage Recognition in GG-NER";"Neddylation";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER"
XP_053991934.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053983486.1	5	Reactome: R-HSA-5693607;Reactome: R-HSA-3232118;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Processing of DNA double-strand break ends";"SUMOylation of transcription factors";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053976789.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053977821.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053986239.1	15	Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-111465;Reactome: R-HSA-5358747;Reactome: R-HSA-5689896;Reactome: R-HSA-3769402;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-196299	"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"S33 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Beta-catenin phosphorylation cascade"
XP_053975125.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053985062.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053981653.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053977364.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_053972131.1	5	MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6121	"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I"
XP_053987451.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053983951.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053971887.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053973577.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_053985880.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events"
XP_053979411.1	6	KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107	"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system"
XP_053992591.1	13	MetaCyc: PWY-561;MetaCyc: PWY-5392;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5913;MetaCyc: PWY-7254;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6728;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2	"Superpathway of glyoxylate cycle and fatty acid degradation";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle VII (acetate-producers)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes"
XP_053981843.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053978580.1	5	KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979	"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)"
XP_053985029.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053993774.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053987095.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053990434.1	2	KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668	"Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053976053.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053976350.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053983134.1	4	Reactome: R-HSA-2129379;Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-216083	"Molecules associated with elastic fibres";"Syndecan interactions";"ECM proteoglycans";"Integrin cell surface interactions"
XP_053990041.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981077.1	11	KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-3881;KEGG: 00520+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-6992	"Fructose and mannose metabolism";"Mannitol degradation II";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Mannitol biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation"
XP_053976460.1	2	KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685	"Glutathione metabolism";"Detoxification of Reactive Oxygen Species"
XP_053975070.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053979537.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053980944.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053970941.1	7	Reactome: R-HSA-8964208;Reactome: R-HSA-2160456;KEGG: 00790+1.14.16.1;MetaCyc: PWY-7158;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1	"Phenylalanine metabolism";"Phenylketonuria";"Folate biosynthesis";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis"
XP_053985249.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_053985882.1	27	Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159230	"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA"
XP_053970711.1	2	Reactome: R-HSA-399719;Reactome: R-HSA-190873	"Trafficking of AMPA receptors";"Gap junction degradation"
XP_053987398.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-171319	"rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase"
XP_053982549.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053989890.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events"
XP_053991551.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053983693.1	5	Reactome: R-HSA-389661;Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88	"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism"
XP_053976352.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053971260.1	1	Reactome: R-HSA-203615	"eNOS activation"
XP_053986649.1	4	Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053982567.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053993568.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053975072.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053990221.1	5	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053986859.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053988934.1	2	Reactome: R-HSA-456926;Reactome: R-HSA-416482	"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events"
XP_053985453.1	4	Reactome: R-HSA-947581;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;MetaCyc: PWY-6823	"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053985060.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053984900.1	56	Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424	"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling"
XP_053988151.1	1	Reactome: R-HSA-425410	"Metal ion SLC transporters"
XP_053983567.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053991375.1	3	Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369	"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis"
XP_053976429.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053992054.1	6	Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387	"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Neutrophil degranulation";"Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling"
XP_053994586.1	5	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053989223.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_053980156.1	15	Reactome: R-HSA-2173796;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-176034;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-6807505;Reactome: R-HSA-112382	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Interactions of Tat with host cellular proteins";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex"
XP_053985961.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053979659.1	4	Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053974004.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053979925.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053981090.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053975097.1	5	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053989342.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053992675.1	56	Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128	"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling"
XP_053970247.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053974040.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053993456.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_053984928.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion"
XP_053991803.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053987275.1	4	KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614	"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage"
XP_053976690.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053983052.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_053990865.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053970316.1	8	Reactome: R-HSA-70268;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00270+1.1.1.27;KEGG: 00640+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901	"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Cysteine and methionine metabolism";"Propanoate metabolism";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation"
XP_053972762.1	1	KEGG: 00051+4.2.1.68	"Fructose and mannose metabolism"
XP_053977973.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053981297.1	4	Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-3304356	"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer"
XP_053989732.1	26	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-190840;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-983189	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Recycling pathway of L1";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Kinesins"
XP_053982837.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_053975290.1	1	Reactome: R-HSA-74217	"Purine salvage"
XP_053993219.1	4	MetaCyc: PWY-7383;MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1	"Anaerobic energy metabolism (invertebrates, cytosol)";"Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism"
XP_053988215.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053990712.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053992509.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053976692.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053991261.1	4	KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726	"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation"
XP_053972760.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_053980615.1	5	MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism"
XP_053991105.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053985998.1	5	Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins"
XP_053985974.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053985557.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053993258.1	14	MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199	"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation"
XP_053979280.1	179	Reactome: R-HSA-2691232;Reactome: R-HSA-9637628;Reactome: R-HSA-5358346;Reactome: R-HSA-1799339;Reactome: R-HSA-8939902;Reactome: R-HSA-2122948;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-72764;Reactome: R-HSA-75815;Reactome: R-HSA-9613829;Reactome: R-HSA-5696394;Reactome: R-HSA-937041;Reactome: R-HSA-8849469;Reactome: R-HSA-2672351;Reactome: R-HSA-110312;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-6783310;Reactome: R-HSA-168928;Reactome: R-HSA-6781827;Reactome: R-HSA-2644606;Reactome: R-HSA-8866654;Reactome: R-HSA-8876493;Reactome: R-HSA-1169408;Reactome: R-HSA-5656121;Reactome: R-HSA-69231;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-937039;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-2122947;Reactome: R-HSA-8852276;Reactome: R-HSA-936964;Reactome: R-HSA-6804757;Reactome: R-HSA-5654727;Reactome: R-HSA-5654732;Reactome: R-HSA-2979096;Reactome: R-HSA-5675482;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-9636383;Reactome: R-HSA-2173795;Reactome: R-HSA-192823;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-195253;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-5696395;Reactome: R-HSA-5668541;Reactome: R-HSA-174048;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-72706;Reactome: R-HSA-201681;Reactome: R-HSA-9604323;Reactome: R-HSA-5357956;Reactome: R-HSA-8941858;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-532668;Reactome: R-HSA-5684264;Reactome: R-HSA-5693607;Reactome: R-HSA-8866652;Reactome: R-HSA-5632684;Reactome: R-HSA-5655862;Reactome: R-HSA-69601;Reactome: R-HSA-209543;Reactome: R-HSA-9013973;Reactome: R-HSA-901032;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-450321;Reactome: R-HSA-5696397;Reactome: R-HSA-174154;Reactome: R-HSA-6791226;Reactome: R-HSA-917937;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-182971;Reactome: R-HSA-5693565;Reactome: R-HSA-2173788;Reactome: R-HSA-5689901;Reactome: R-HSA-400253;Reactome: R-HSA-1169091;Reactome: R-HSA-5205685;Reactome: R-HSA-9615710;Reactome: R-HSA-8863795;Reactome: R-HSA-9646399;Reactome: R-HSA-9645460;Reactome: R-HSA-5676590;Reactome: R-HSA-4641263;Reactome: R-HSA-8951664;Reactome: R-HSA-9033241;Reactome: R-HSA-5610783;Reactome: R-HSA-1236382;Reactome: R-HSA-8948747;Reactome: R-HSA-3785653;Reactome: R-HSA-175474;Reactome: R-HSA-187577;Reactome: R-HSA-6804760;Reactome: R-HSA-4641258;Reactome: R-HSA-5675221;Reactome: R-HSA-5689877;Reactome: R-HSA-1295596;Reactome: R-HSA-180585;Reactome: R-HSA-3322077;Reactome: R-HSA-69541;Reactome: R-HSA-1358803;Reactome: R-HSA-937072;Reactome: R-HSA-3769402;Reactome: R-HSA-4608870;Reactome: R-HSA-912631;Reactome: R-HSA-975957;Reactome: R-HSA-2565942;Reactome: R-HSA-9633012;Reactome: R-HSA-2173791;Reactome: R-HSA-5357905;Reactome: R-HSA-110314;Reactome: R-HSA-68949;Reactome: R-HSA-2559585;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-382556;Reactome: R-HSA-8875360;Reactome: R-HSA-6782135;Reactome: R-HSA-156902;Reactome: R-HSA-5689603;Reactome: R-HSA-1253288;Reactome: R-HSA-2559582;Reactome: R-HSA-4641257;Reactome: R-HSA-2173796;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-5654733;Reactome: R-HSA-5656169;Reactome: R-HSA-69481;Reactome: R-HSA-72689;Reactome: R-HSA-6807004;Reactome: R-HSA-6781823;Reactome: R-HSA-174178;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-5696400;Reactome: R-HSA-3134975;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-2559580;Reactome: R-HSA-975110;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-5689896;Reactome: R-HSA-209560;Reactome: R-HSA-211733;Reactome: R-HSA-8856825;Reactome: R-HSA-5607761;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-6804756;Reactome: R-HSA-5654726;Reactome: R-HSA-975144;Reactome: R-HSA-8856828;Reactome: R-HSA-168927;Reactome: R-HSA-5685942;Reactome: R-HSA-162588;Reactome: R-HSA-1234176;Reactome: R-HSA-936440;Reactome: R-HSA-2894862;Reactome: R-HSA-205043;Reactome: R-HSA-2467813	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Modulation by Mtb of host immune system";"Hedgehog ligand biogenesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of RUNX2 expression and activity";"Activated NOTCH1 Transmits Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Eukaryotic Translation Termination";"Ubiquitin-dependent degradation of Cyclin D";"Chaperone Mediated Autophagy";"DNA Damage Recognition in GG-NER";"IKK complex recruitment mediated by RIP1";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Stimuli-sensing channels";"Translesion synthesis by REV1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Fanconi Anemia Pathway";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"E3 ubiquitin ligases ubiquitinate target proteins";"InlA-mediated entry of Listeria monocytogenes into host cells";"ISG15 antiviral mechanism";"Translesion synthesis by POLI";"Cyclin D associated events in G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"IRAK1 recruits IKK complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"NOTCH1 Intracellular Domain Regulates Transcription";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of TP53 Degradation";"Negative regulation of FGFR2 signaling";"Negative regulation of FGFR3 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Regulation of necroptotic cell death";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Prevention of phagosomal-lysosomal fusion";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Viral mRNA Translation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Degradation of beta-catenin by the destruction complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Formation of Incision Complex in GG-NER";"TNFR2 non-canonical NF-kB pathway";"APC/C:Cdc20 mediated degradation of Cyclin B";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TCF dependent signaling in response to WNT";"Negative regulation of NOTCH4 signaling";"TNFR1-induced NFkappaB signaling pathway";"Regulation of RUNX3 expression and activity";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Processing of DNA double-strand break ends";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Hedgehog 'on' state";"Translesion synthesis by POLK";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"p75NTR recruits signalling complexes";"TICAM1-dependent activation of IRF3/IRF7";"ER Quality Control Compartment (ERQC)";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"APC/C:Cdc20 mediated degradation of Securin";"Major pathway of rRNA processing in the nucleolus and cytosol";"Iron uptake and transport";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"EGFR downregulation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Downregulation of TGF-beta receptor signaling";"Metalloprotease DUBs";"Circadian Clock";"Activation of NF-kappaB in B cells";"Pink/Parkin Mediated Mitophagy";"Late endosomal microautophagy";"Downregulation of ERBB2 signaling";"Aggrephagy";"Alpha-protein kinase 1 signaling pathway";"NIK-->noncanonical NF-kB signaling";"Regulation of FZD by ubiquitination";"Neddylation";"Peroxisomal protein import";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of PTEN localization";"Myoclonic epilepsy of Lafora";"Assembly Of The HIV Virion";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of TP53 Activity through Methylation";"Degradation of DVL";"Negative regulation of MAPK pathway";"Josephin domain DUBs";"Spry regulation of FGF signaling";"Vif-mediated degradation of APOBEC3G";"Glycogen synthesis";"Stabilization of p53";"Downregulation of ERBB2:ERBB3 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Deactivation of the beta-catenin transactivating complex";"Asymmetric localization of PCP proteins";"Regulation of signaling by CBL";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of PLK1 Activity at G2/M Transition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of TNFR1 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Orc1 removal from chromatin";"Oncogene Induced Senescence";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"ABC-family proteins mediated transport";"InlB-mediated entry of Listeria monocytogenes into host cell";"Dual incision in TC-NER";"Peptide chain elongation";"UCH proteinases";"Downregulation of ERBB4 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"Degradation of AXIN";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Negative regulation of FGFR4 signaling";"Termination of translesion DNA synthesis";"G2/M Checkpoints";"Formation of a pool of free 40S subunits";"Negative regulation of MET activity";"Formation of TC-NER Pre-Incision Complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Dual Incision in GG-NER";"Regulation of innate immune responses to cytosolic DNA";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Oxidative Stress Induced Senescence";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Ovarian tumor domain proteases";"NF-kB is activated and signals survival";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cargo recognition for clathrin-mediated endocytosis";"Dectin-1 mediated noncanonical NF-kB signaling";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of TP53 Activity through Phosphorylation";"Negative regulation of FGFR1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Clathrin-mediated endocytosis";"TICAM1, RIP1-mediated IKK complex recruitment";"HDR through Homologous Recombination (HRR)";"Budding and maturation of HIV virion";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulators of DDX58/IFIH1 signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus";"Separation of Sister Chromatids"
XP_053991496.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_053977989.1	1	Reactome: R-HSA-380972	"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053994710.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053973760.1	26	Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-933541;Reactome: R-HSA-2122947;Reactome: R-HSA-1989781;Reactome: R-HSA-8866907;Reactome: R-HSA-9614657;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-9018519;Reactome: R-HSA-3214847;Reactome: R-HSA-3134973;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856;Reactome: R-HSA-381340;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-1912408;Reactome: R-HSA-3371568;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-9013695	"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"RORA activates gene expression";"Circadian Clock";"TRAF6 mediated IRF7 activation";"NOTCH1 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"Activation of the TFAP2 (AP-2) family of transcription factors";"FOXO-mediated transcription of cell death genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Estrogen-dependent gene expression";"HATs acetylate histones";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"Transcriptional regulation of white adipocyte differentiation";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"Pre-NOTCH Transcription and Translation";"Attenuation phase";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_053987104.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053981092.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053989340.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053984279.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_053979433.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053977265.1	14	MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725	"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)"
XP_053995064.1	10	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_053988442.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053974042.1	2	Reactome: R-HSA-445095;Reactome: R-HSA-5576892	"Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation"
XP_053989877.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053989304.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053974637.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_053974220.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053972057.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053973673.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053979194.1	2	Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2	"Signaling by SCF-KIT";"T cell receptor signaling pathway"
XP_053978318.1	6	Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6782210	"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053994983.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053979347.1	5	Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695	"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation"
XP_053977169.1	3	Reactome: R-HSA-5619078;Reactome: R-HSA-6787639;Reactome: R-HSA-727802	"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis";"Transport of nucleotide sugars"
XP_053984175.1	2	Reactome: R-HSA-8934593;Reactome: R-HSA-69231	"Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1"
XP_053970718.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053973250.1	2	MetaCyc: PWY-7533;Reactome: R-HSA-1268020	"Gliotoxin biosynthesis";"Mitochondrial protein import"
XP_053978601.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053986793.1	2	MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21	"Mitochondrial L-carnitine shuttle";"Fatty acid degradation"
XP_053992846.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053992813.1	2	KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041	"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II"
XP_053984630.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053984323.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053980630.1	17	MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6627;MetaCyc: PWY-6611;KEGG: 00760+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;Reactome: R-HSA-74259;MetaCyc: PWY-6644;MetaCyc: PWY-6620;MetaCyc: PWY-6609;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-5532;Reactome: R-HSA-74217;MetaCyc: PWY-7179	"Guanosine nucleotides degradation III";"Purine metabolism";"Salinosporamide A biosynthesis";"Adenine and adenosine salvage V";"Nicotinate and nicotinamide metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Purine catabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Purine salvage";"Purine deoxyribonucleosides degradation I"
XP_053980227.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053977122.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_053987419.1	5	Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164	"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade"
XP_053993768.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_053984242.1	1	Reactome: R-HSA-2470946	"Cohesin Loading onto Chromatin"
XP_053990786.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_053979737.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_053974863.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053972832.1	3	Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway"
XP_053980514.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7589	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_053995105.1	5	MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14	"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism"
XP_053974079.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053970511.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053978782.1	8	Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411	"Activation of the pre-replicative complex";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere"
XP_053989715.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_053994979.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053988119.1	10	Reactome: R-HSA-8934903;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-201688	"Receptor Mediated Mitophagy";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Synthesis of PC";"WNT mediated activation of DVL"
XP_053991696.1	3	Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33	"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis"
XP_053990426.1	7	MetaCyc: PWY-4702;KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363	"Phytate degradation I";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation"
XP_053977120.1	2	Reactome: R-HSA-8862803;Reactome: R-HSA-69273	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053971290.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_053972830.1	4	Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5188	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_053973777.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053988230.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053993598.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053979023.1	57	Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053982958.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053993574.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053978780.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation"
XP_053990048.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053989082.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053978469.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053978015.1	14	KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-975634;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;Reactome: R-HSA-1482788	"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Acyl chain remodelling of PC"
XP_053979506.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053984873.1	1	Reactome: R-HSA-1660662	"Glycosphingolipid metabolism"
XP_053975184.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053985181.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053971097.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053970759.1	2	Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13	"RHO GTPases activate PKNs";"Phosphatidylinositol signaling system"
XP_053979418.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053978447.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053983958.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053991519.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053980022.1	14	KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-561;MetaCyc: PWY-7279;KEGG: 00190+1.3.5.1;Reactome: R-HSA-71403;Reactome: R-HSA-611105;MetaCyc: PWY-6728;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254	"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)"
XP_053977075.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_053974083.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053984632.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation"
XP_053975978.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_053985272.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_053975994.1	34	Reactome: R-HSA-69273;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-69656;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-69202;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-69231;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-8939236;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Cyclin E associated events during G1/S transition";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin D associated events in G1";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053976477.1	8	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053981363.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053982572.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053975067.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053981060.1	3	Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053971389.1	3	MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2	"Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism"
XP_053971823.1	9	KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"tRNA modification in the nucleus and cytosol";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053986672.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053975049.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7800	"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway"
XP_053990202.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68867	"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Assembly of the pre-replicative complex"
XP_053989530.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA"
XP_053983572.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053981882.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053972792.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053975260.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"DARPP-32 events";"PKA activation";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053989614.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053992709.1	15	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-9018519;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Estrogen-dependent gene expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence"
XP_053971072.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053979005.1	3	Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355	"Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction"
XP_053971752.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-110320	"Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH"
XP_053978543.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053975887.1	12	KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;MetaCyc: PWY-5278;MetaCyc: PWY-5340;Reactome: R-HSA-174362;MetaCyc: PWY-6932;KEGG: 00261+2.7.7.4	"Sulfur metabolism";"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Selenate reduction";"Monobactam biosynthesis"
XP_053978516.1	8	KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1	"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_053986449.1	5	MetaCyc: PWY-7177;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7185	"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I"
XP_053972790.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053991291.1	7	Reactome: R-HSA-110329;Reactome: R-HSA-2559586;Reactome: R-HSA-110331;Reactome: R-HSA-171306;Reactome: R-HSA-110328;Reactome: R-HSA-1221632;Reactome: R-HSA-110330	"Cleavage of the damaged pyrimidine";"DNA Damage/Telomere Stress Induced Senescence";"Cleavage of the damaged purine";"Packaging Of Telomere Ends";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_053984921.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053974924.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053976662.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_053975262.1	8	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-381676	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_053978408.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053994244.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053986357.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51	"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_053981188.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053974606.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053985077.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053976955.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053971277.1	4	Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"ECM proteoglycans";"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053994193.1	6	Reactome: R-HSA-1855204;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368	"Synthesis of IP3 and IP4 in the cytosol";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation"
XP_053993831.1	4	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053985270.1	2	Reactome: R-HSA-3108214;MetaCyc: PWY-7511	"SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination"
XP_053982570.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053979984.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053981062.1	3	Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins"
XP_053990244.1	2	MetaCyc: PWY-6531;KEGG: 00051+1.1.1.17	"Mannitol cycle";"Fructose and mannose metabolism"
XP_053991187.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053987309.1	4	Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6	"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053986186.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_053981639.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053995078.1	3	Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17	"Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism"
XP_053986135.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053975229.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053976117.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053986670.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053987796.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053976329.1	8	Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571	"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"HSF1-dependent transactivation"
XP_053991475.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_053991846.1	7	Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-1268020	"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"ATP biosynthesis";"Mitochondrial protein import"
XP_053992558.1	16	Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-388841;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-1266695;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-6811558	"Interleukin receptor SHC signaling";"RET signaling";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"Costimulation by the CD28 family";"PIP3 activates AKT signaling";"Rho GTPase cycle";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Interleukin-7 signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_053983974.1	2	Reactome: R-HSA-6804756;Reactome: R-HSA-8854518	"Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2"
XP_053975489.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_053992064.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053981339.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053980011.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053993209.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053988205.1	14	KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-3781;MetaCyc: PWY-6728;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-7254;KEGG: 00720+1.3.5.1	"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Methylaspartate cycle";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes"
XP_053981919.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053971250.1	2	Reactome: R-HSA-70350;Reactome: R-HSA-168928	"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta"
XP_053988414.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053974014.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053980579.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053978411.1	6	Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-5651801;Reactome: R-HSA-110357	"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1"
XP_053972292.1	1	Reactome: R-HSA-196783	"Coenzyme A biosynthesis"
XP_053976452.1	5	Reactome: R-HSA-2206305;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857	"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Keratan sulfate degradation"
XP_053982557.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053992209.1	5	KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-75109;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Triglyceride biosynthesis";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism"
XP_053975146.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053974306.1	8	Reactome: R-HSA-113501;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430	"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation"
XP_053970520.1	6	KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_053986822.1	7	Reactome: R-HSA-500753;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10	"Pyrimidine biosynthesis";"UMP biosynthesis III";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_053977471.1	1	Reactome: R-HSA-6804760	"Regulation of TP53 Activity through Methylation"
XP_053986657.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053973103.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053994700.1	2	Reactome: R-HSA-1482798;Reactome: R-HSA-1268020	"Acyl chain remodeling of CL";"Mitochondrial protein import"
XP_053971252.1	2	Reactome: R-HSA-168928;Reactome: R-HSA-70350	"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism"
XP_053987114.1	44	Reactome: R-HSA-5674499;Reactome: R-HSA-8939211;Reactome: R-HSA-162658;Reactome: R-HSA-982772;Reactome: R-HSA-2559580;Reactome: R-HSA-1295596;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-5675221;Reactome: R-HSA-202670;Reactome: R-HSA-2029482;Reactome: R-HSA-8943724;Reactome: R-HSA-5673001;Reactome: R-HSA-5654733;Reactome: R-HSA-5674135;Reactome: R-HSA-6802946;Reactome: R-HSA-5663213;Reactome: R-HSA-198753;Reactome: R-HSA-9634638;Reactome: R-HSA-170968;Reactome: R-HSA-6802952;Reactome: R-HSA-2559585;Reactome: R-HSA-2559582;Reactome: R-HSA-6802955;Reactome: R-HSA-112409;Reactome: R-HSA-445144;Reactome: R-HSA-444257;Reactome: R-HSA-5668599;Reactome: R-HSA-74749;Reactome: R-HSA-8940973;Reactome: R-HSA-375165;Reactome: R-HSA-3371453;Reactome: R-HSA-879415;Reactome: R-HSA-456926;Reactome: R-HSA-6811558;Reactome: R-HSA-9649948;Reactome: R-HSA-9627069;Reactome: R-HSA-9635465;Reactome: R-HSA-881907;Reactome: R-HSA-5654732;Reactome: R-HSA-6802948;Reactome: R-HSA-5654726;Reactome: R-HSA-5654727;Reactome: R-HSA-2871796	"Negative feedback regulation of MAPK pathway";"ESR-mediated signaling";"Golgi Cisternae Pericentriolar Stack Reorganization";"Growth hormone receptor signaling";"Oxidative Stress Induced Senescence";"Spry regulation of FGF signaling";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"Negative regulation of MAPK pathway";"ERKs are inactivated";"Regulation of actin dynamics for phagocytic cup formation";"Regulation of PTEN gene transcription";"RAF/MAP kinase cascade";"Negative regulation of FGFR4 signaling";"MAP2K and MAPK activation";"Signaling by moderate kinase activity BRAF mutants";"RHO GTPases Activate WASPs and WAVEs";"ERK/MAPK targets";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Frs2-mediated activation";"Signaling by BRAF and RAF fusions";"Oncogene Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"RAF-independent MAPK1/3 activation";"Signal transduction by L1";"RSK activation";"RHO GTPases Activate NADPH Oxidases";"Signal attenuation";"RUNX2 regulates osteoblast differentiation";"NCAM signaling for neurite out-growth";"Regulation of HSF1-mediated heat shock response";"Advanced glycosylation endproduct receptor signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Signaling downstream of RAS mutants";"Regulation of the apoptosome activity";"Suppression of apoptosis";"Gastrin-CREB signalling pathway via PKC and MAPK";"Negative regulation of FGFR3 signaling";"Signaling by high-kinase activity BRAF mutants";"Negative regulation of FGFR1 signaling";"Negative regulation of FGFR2 signaling";"FCERI mediated MAPK activation"
XP_053989006.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053972290.1	3	Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228	"Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix"
XP_053988515.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053974569.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042	"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance"
XP_053984605.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053983961.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053990334.1	6	MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_053975762.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122	"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053979311.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053979499.1	5	KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084	"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA"
XP_053992519.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053971777.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053973290.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053977354.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053986956.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053991957.1	7	Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450;Reactome: R-HSA-6798695	"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC";"Neutrophil degranulation"
XP_053990914.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053980605.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_053979154.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053993071.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053989151.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053972097.1	1	Reactome: R-HSA-2565942	"Regulation of PLK1 Activity at G2/M Transition"
XP_053982961.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053972964.1	4	MetaCyc: PWY-6823;KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053976136.1	5	MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053993696.1	14	Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_053977255.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053983267.1	1	Reactome: R-HSA-8943724	"Regulation of PTEN gene transcription"
XP_053985693.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952	"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions"
XP_053988223.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053992268.1	14	KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-7417	"Glycerophospholipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)"
XP_053972823.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053995054.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053989404.1	6	KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-7165;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17	"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II";"L-ascorbate biosynthesis VI (engineered pathway)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Caprolactam degradation"
XP_053979333.1	2	MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70	"Pseudouridine degradation";"Pyrimidine metabolism"
XP_053972389.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053994286.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053982060.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_053974680.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053983249.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_053983882.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053989440.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053976995.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053984727.1	6	Reactome: R-HSA-2046105;Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-5684045;Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053986293.1	7	Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_053971560.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053977066.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053991396.1	3	Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420	"Arachidonate production from DAG";"Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)"
XP_053980727.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053987668.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053984742.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053974218.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053982267.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053978867.1	2	Reactome: R-HSA-3371599;Reactome: R-HSA-196780	"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism"
XP_053970680.1	12	KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418885;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476	"Relaxin signaling pathway";"NRAGE signals death through JNK";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"DCC mediated attractive signaling";"Rho GTPase cycle";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Thermogenesis";"G alpha (q) signalling events"
XP_053990235.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-110320	"Ub-specific processing proteases";"Translesion Synthesis by POLH"
XP_053989215.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053978849.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053983060.1	4	Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053988327.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_053982249.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053972373.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053982188.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053992356.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053984623.1	6	Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974	"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA"
XP_053980330.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053970682.1	12	KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"NRAGE signals death through JNK";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Rho GTPase cycle";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"G alpha (q) signalling events";"Thermogenesis"
XP_053970443.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053973277.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053974701.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983062.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308	"Phase 2 - plateau phase";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening"
XP_053979857.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053980487.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053993356.1	2	Reactome: R-HSA-5362517;Reactome: R-HSA-204174	"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex"
XP_053975131.1	2	KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240	"Tryptophan metabolism";"Tryptophan catabolism"
XP_053971529.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053980704.1	11	KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"PI3K-Akt signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"Thermogenesis";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053974443.1	9	Reactome: R-HSA-112043;MetaCyc: PWY-6351;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204	"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol"
XP_053989505.1	1	Reactome: R-HSA-193648	"NRAGE signals death through JNK"
XP_053992187.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053989683.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053988340.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053977886.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952	"MAP2K and MAPK activation";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions"
XP_053982062.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053984033.1	4	MetaCyc: PWY-7849;KEGG: 00230+4.1.1.97;MetaCyc: PWY-5691;MetaCyc: PWY-7394	"Urate conversion to allantoin III";"Purine metabolism";"Urate conversion to allantoin I";"Urate conversion to allantoin II"
XP_053983880.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053970259.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053993291.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053988304.1	3	Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619	"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI"
XP_053978301.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053988080.1	13	Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6802955	"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Human immunodeficiency virus 1 infection";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"MAP2K and MAPK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Paradoxical activation of RAF signaling by kinase inactive BRAF"
XP_053978178.1	7	Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053983968.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053989640.1	1	Reactome: R-HSA-8963901	"Chylomicron remodeling"
XP_053988383.1	5	Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Neutrophil degranulation";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs"
XP_053988191.1	13	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis"
XP_053988829.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053990500.1	9	Reactome: R-HSA-3656535;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603	"TGFBR1 LBD Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"UCH proteinases"
XP_053979318.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053992078.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_053992949.1	56	Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113	"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1"
XP_053984059.1	34	Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-9639288;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-159236	"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Amino acids regulate mTORC1";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053973887.1	13	Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053974337.1	5	MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560	"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Terpenoid backbone biosynthesis";"Thiamine metabolism";"Methylerythritol phosphate pathway II"
XP_053974722.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053978369.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053984315.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053986121.1	3	Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium"
XP_053978870.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_053983843.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053986553.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053991798.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053983816.1	19	MetaCyc: PWY-7115;MetaCyc: PWY-7383;Reactome: R-HSA-71403;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00680+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-5392;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-561	"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Citric acid cycle (TCA cycle)";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Superpathway of glyoxylate cycle and fatty acid degradation"
XP_053987775.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053984935.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_053993094.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053984783.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053979420.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695	"Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation"
XP_053984986.1	17	Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-975163;Reactome: R-HSA-450321;Reactome: R-HSA-445989;Reactome: R-HSA-9645460;Reactome: R-HSA-202424;Reactome: R-HSA-937042;Reactome: R-HSA-4086398;Reactome: R-HSA-937072;Reactome: R-HSA-9014325;Reactome: R-HSA-168638;Reactome: R-HSA-9020702;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-450302	"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Alpha-protein kinase 1 signaling pathway";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex";"Ca2+ pathway";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"NOD1/2 Signaling Pathway";"Interleukin-1 signaling";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"activated TAK1 mediates p38 MAPK activation"
XP_053989158.1	6	Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_053993078.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053973229.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053974917.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_053988862.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053978216.1	7	Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942	"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition"
XP_053975790.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053983270.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053993949.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053990212.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053972887.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053981567.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053982145.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053970616.1	9	Reactome: R-HSA-6798695;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208	"Neutrophil degranulation";"TP53 Regulates Metabolic Genes";"Macroautophagy";"mTOR signalling";"Amino acids regulate mTORC1";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling"
XP_053976093.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053974599.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053994876.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-168276	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways"
XP_053991761.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053988860.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053975792.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053992666.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_053988168.1	9	Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324	"EPHB-mediated forward signaling";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission"
XP_053980779.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053994017.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053989852.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-8876198	"Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs"
XP_053970482.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053988082.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053978633.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053994210.1	2	MetaCyc: PWY-6829;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol"
XP_053973260.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053990688.1	5	Reactome: R-HSA-75105;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-9029558;Reactome: R-HSA-163765	"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression"
XP_053990017.1	3	Reactome: R-HSA-881907;Reactome: R-HSA-416476;Reactome: R-HSA-375276	"Gastrin-CREB signalling pathway via PKC and MAPK";"G alpha (q) signalling events";"Peptide ligand-binding receptors"
XP_053981693.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053977494.1	6	Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-912446	"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination"
XP_053983145.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_053987491.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053984018.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_053972067.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736	"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors"
XP_053970599.1	3	Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-5362798	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Release of Hh-Np from the secreting cell"
XP_053974720.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053993666.1	9	Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-9608290;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9608287	"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Defective MUTYH substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Defective MUTYH substrate binding"
XP_053987266.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_053978872.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053977159.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053989483.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053992274.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation"
XP_053975777.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Protein ubiquitination";"Neutrophil degranulation"
XP_053991838.1	2	Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58	"Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis"
XP_053992298.1	3	Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053983297.1	7	MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461	"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation"
XP_053980540.1	8	Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"DARPP-32 events";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053987409.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids"
XP_053979206.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053986263.1	12	Reactome: R-HSA-8853383;Reactome: R-HSA-2160916;KEGG: 00511+3.2.1.23;KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23	"Lysosomal oligosaccharide catabolism";"Hyaluronan uptake and degradation";"Other glycan degradation";"Other glycan degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"HS-GAG degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series"
XP_053982909.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053971473.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053991366.1	5	Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185	"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I"
XP_053978897.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053993274.1	8	Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-380972;Reactome: R-HSA-9613354	"Macroautophagy";"TP53 Regulates Metabolic Genes";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy"
XP_053993298.1	6	Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957	"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053987698.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_053971762.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053970708.1	2	Reactome: R-HSA-190873;Reactome: R-HSA-399719	"Gap junction degradation";"Trafficking of AMPA receptors"
XP_053988614.1	5	KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-7382	"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053994528.1	12	Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053985749.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-2173788	"UCH proteinases";"Downregulation of TGF-beta receptor signaling"
XP_053986975.1	2	Reactome: R-HSA-2022854;Reactome: R-HSA-975577	"Keratan sulfate biosynthesis";"N-Glycan antennae elongation"
XP_053981257.1	31	Reactome: R-HSA-75105;MetaCyc: PWY-7388;MetaCyc: PWY-5142;MetaCyc: PWY-5966-1;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-5994;Reactome: R-HSA-163765;MetaCyc: PWY-8049;MetaCyc: PWY-7858;MetaCyc: PWY-7723;MetaCyc: PWY-7663;MetaCyc: PWY-6282;MetaCyc: PWY-6799;MetaCyc: PWY-8012;MetaCyc: PWYG-321;Reactome: R-HSA-9029558;MetaCyc: PWY-5147;MetaCyc: PWY-4381;MetaCyc: PWY-5366;MetaCyc: PWY-7746;Reactome: R-HSA-199220;MetaCyc: PWY-6113;MetaCyc: PWY-5367;MetaCyc: PWY-7664;Reactome: R-HSA-2426168;MetaCyc: PWY-8047;MetaCyc: PWY-5973;MetaCyc: PWY-6519;MetaCyc: PWY-5989;MetaCyc: PWY-5971;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14	"Fatty acyl-CoA biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"ChREBP activates metabolic gene expression";"Pederin biosynthesis";"(5Z)-dodecenoate biosynthesis II";"Bacterial bioluminescence";"Gondoate biosynthesis (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Mupirocin biosynthesis";"";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Mycobacterial sulfolipid biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Superpathway of mycolate biosynthesis";"Petroselinate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Activation of gene expression by SREBF (SREBP)";"Bryostatin biosynthesis";"Cis-vaccenate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Stearate biosynthesis II (bacteria and plants)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis"
XP_053979543.1	1	Reactome: R-HSA-201681	"TCF dependent signaling in response to WNT"
XP_053979516.1	5	Reactome: R-HSA-6798695;Reactome: R-HSA-964975;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7204;MetaCyc: PWY-7282	"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_053985919.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053989587.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_053992105.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053979408.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_053980527.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053985767.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053990721.1	10	MetaCyc: PWY-6901;MetaCyc: PWY-6891;KEGG: 00710+2.2.1.1;MetaCyc: PWY-1861;MetaCyc: PWY-5723;MetaCyc: PWY-6892;KEGG: 00030+2.2.1.1;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560	"Superpathway of glucose and xylose degradation";"Thiazole biosynthesis II (aerobic bacteria)";"Carbon fixation in photosynthetic organisms";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Pentose phosphate pathway";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II"
XP_053983092.1	57	Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585	"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G"
XP_053994721.1	7	Reactome: R-HSA-6798695;MetaCyc: PWY-5941;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238;MetaCyc: PWY-6724;MetaCyc: PWY-6737	"Neutrophil degranulation";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Starch degradation II";"Starch degradation V"
XP_053988109.1	5	Reactome: R-HSA-189451;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188	"Heme biosynthesis";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_053993105.1	6	Reactome: R-HSA-6798695;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-983712	"Neutrophil degranulation";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Ion channel transport"
XP_053988981.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053975057.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053981353.1	2	Reactome: R-HSA-71403;Reactome: R-HSA-611105	"Citric acid cycle (TCA cycle)";"Respiratory electron transport"
XP_053976148.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_053991132.1	9	Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"RORA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053977664.1	2	KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749	"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I"
XP_053974211.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053984214.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053985339.1	57	Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-4641258	"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL"
XP_053983226.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053992404.1	13	Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-156902	"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation"
XP_053974989.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_053971081.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053990869.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053985197.1	10	MetaCyc: PWY-7391;MetaCyc: PWY-7571;MetaCyc: PWY-6174;KEGG: 00900+2.3.3.10;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-922	"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Butanoate metabolism";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway I"
XP_053981084.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053987432.1	6	Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Protein ubiquitination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway"
XP_053972152.1	7	Reactome: R-HSA-110362;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939;Reactome: R-HSA-5696395	"POLB-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)";"Formation of Incision Complex in GG-NER"
XP_053986702.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053984104.1	7	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_053979476.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053972819.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053994657.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053975538.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053974265.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_053972238.1	24	Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-9009391;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-392451	"G alpha (z) signalling events";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"Extra-nuclear estrogen signaling";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma"
XP_053985003.1	4	Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053984766.1	9	Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146	"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism"
XP_053971307.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983581.1	2	Reactome: R-HSA-5205685;Reactome: R-HSA-983231	"Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production"
XP_053981871.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053992679.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_053977027.1	3	Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588	"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"
XP_053980963.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053980140.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053982312.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_053980766.1	4	Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4	"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_053993404.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053976896.1	6	Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6362	"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)"
XP_053980104.1	8	KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053975731.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053994869.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053980848.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_053992427.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053983428.1	14	Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-9634638	"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling"
XP_053994956.1	3	Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596	"Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I"
XP_053984275.1	9	Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473	"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint"
XP_053989466.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_053982310.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_053981864.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-6807505	"mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes"
XP_053975809.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053972648.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053974973.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053977936.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053989356.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_053980596.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053989291.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-6811436	"RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053979294.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_053976548.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_053972436.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_053977269.1	3	MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_053984619.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053987001.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053979960.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053980619.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994128.1	13	Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-114508	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis"
XP_053992683.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053989187.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-2559582	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)"
XP_053982428.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053980127.1	5	Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148	"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053971546.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053970973.1	3	KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation"
XP_053988258.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053994089.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_053976911.1	4	Reactome: R-HSA-446210;MetaCyc: PWY-6906;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59	"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism"
XP_053980275.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_053987928.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-432047	"Ion transport by P-type ATPases";"Passive transport by Aquaporins"
XP_053988774.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053975162.1	7	KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7234;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-6123	"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I"
XP_053985025.1	7	MetaCyc: PWY-882;MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205	"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose"
XP_053988798.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes"
XP_053983621.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053973624.1	13	Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928663	"EPHB-mediated forward signaling";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"EPHA-mediated growth cone collapse"
XP_053994808.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053990293.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053982444.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053972441.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053994100.1	1	Reactome: R-HSA-3295583	"TRP channels"
XP_053991829.1	56	Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880	"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases"
XP_053976010.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053973703.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053982031.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053976346.1	4	KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247	"Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids"
XP_053991080.1	12	Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00920+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;MetaCyc: PWY-5278;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;KEGG: 00450+2.7.7.4;KEGG: 00920+2.7.1.25	"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Sulfur metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Sulfite oxidation III";"Selenate reduction";"Purine metabolism";"Selenocompound metabolism";"Sulfur metabolism"
XP_053977941.1	12	Reactome: R-HSA-1268020;MetaCyc: PWY-5871;MetaCyc: PWY-5857;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-6978;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5872	"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Plastoquinol-9 biosynthesis II";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)"
XP_053982400.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053977711.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053991191.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053986286.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053984807.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053975129.1	1	MetaCyc: PWY-6308	"L-cysteine biosynthesis II (tRNA-dependent)"
XP_053971531.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053986235.1	1	Reactome: R-HSA-4085001	"Sialic acid metabolism"
XP_053983444.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053972624.1	27	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins"
XP_053977406.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053970555.1	2	Reactome: R-HSA-8953750;Reactome: R-HSA-8939243	"Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053971177.1	4	Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255	"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis"
XP_053981610.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053989209.1	2	Reactome: R-HSA-1369062;Reactome: R-HSA-9603798	"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import"
XP_053990808.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol"
XP_053975088.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053990397.1	7	KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301	"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis"
XP_053994293.1	5	MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539	"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism"
XP_053977518.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053986153.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053986521.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053973607.1	13	KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 04714+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-5627117;Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Human papillomavirus infection";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"EPHA-mediated growth cone collapse";"Thermogenesis";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"RHO GTPases Activate ROCKs";"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053993934.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_053978495.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053986855.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053983545.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053991168.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053981612.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053994539.1	3	KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695	"Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation"
XP_053991860.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053983402.1	2	Reactome: R-HSA-8876725;Reactome: R-HSA-611105	"Protein methylation";"Respiratory electron transport"
XP_053993523.1	1	Reactome: R-HSA-3108214	"SUMOylation of DNA damage response and repair proteins"
XP_053992314.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053980824.1	13	Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171	"Integrin cell surface interactions";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Anchoring fibril formation";"Signaling by PDGF";"NCAM1 interactions";"ECM proteoglycans";"Laminin interactions";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Non-integrin membrane-ECM interactions"
XP_053993151.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053975385.1	1	Reactome: R-HSA-419037	"NCAM1 interactions"
XP_053979074.1	24	Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736	"Gap junction assembly";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors"
XP_053975916.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053975160.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053975943.1	3	MetaCyc: PWY-5686;Reactome: R-HSA-500753;KEGG: 00240+1.3.5.2	"UMP biosynthesis I";"Pyrimidine biosynthesis";"Pyrimidine metabolism"
XP_053982545.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053985328.1	1	Reactome: R-HSA-197264	"Nicotinamide salvaging"
XP_053985245.1	1	Reactome: R-HSA-6807878	"COPI-mediated anterograde transport"
XP_053971980.1	5	Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-182971	"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation"
XP_053977208.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053981149.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053984361.1	37	Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-9639288;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-204005;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-983170;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-2132295	"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Amino acids regulate mTORC1";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"COPII-mediated vesicle transport";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"MHC class II antigen presentation"
XP_053976012.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053975868.1	3	Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159	"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)"
XP_053984451.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053982402.1	1	Reactome: R-HSA-1296052	"Ca2+ activated K+ channels"
XP_053971713.1	12	Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948	"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus"
XP_053971746.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053990899.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053983854.1	2	KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme biosynthesis"
XP_053990121.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053982600.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053976541.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053973851.1	9	Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-6782210	"Formation of Incision Complex in GG-NER";"Neddylation";"DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053983421.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053984993.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053972641.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053982644.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053981410.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053983600.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053991327.1	18	Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167243	"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery"
XP_053980309.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053976918.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_053994121.1	13	Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-2871809	"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization"
XP_053981172.1	3	MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105	"Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis"
XP_053975045.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053993705.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053985612.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053973641.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053988396.1	2	Reactome: R-HSA-5683371;Reactome: R-HSA-1369007	"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters"
XP_053983602.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053981878.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053992587.1	5	Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053978834.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053988831.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053976959.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053979264.1	18	MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482839	"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE"
XP_053984841.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_053981170.1	3	MetaCyc: PWY-5996;MetaCyc: PWY-5987;Reactome: R-HSA-75105	"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis";"Fatty acyl-CoA biosynthesis"
XP_053989261.1	11	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-5693616	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange"
XP_053980651.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)"
XP_053985726.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985610.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053978695.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053975225.1	4	Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053987305.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053981635.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053991877.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053982588.1	5	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053973231.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053991304.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053971162.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053986445.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053977907.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053980841.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053970844.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053985288.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053986017.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_053991016.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053991340.1	20	Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-174411;Reactome: R-HSA-110314	"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLI";"Polymerase switching";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053976035.1	8	Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes"
XP_053979676.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053991205.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes"
XP_053992723.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053992926.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053987415.1	5	Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041	"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1"
XP_053993158.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053989094.1	3	Reactome: R-HSA-450385;Reactome: R-HSA-430039;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053976707.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053973317.1	7	Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-140837;Reactome: R-HSA-375276	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation";"G alpha (i) signalling events";"G alpha (q) signalling events";"Intrinsic Pathway of Fibrin Clot Formation";"Peptide ligand-binding receptors"
XP_053987047.1	7	KEGG: 00250+2.4.2.14;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-7282	"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis"
XP_053975546.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_053975513.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053980368.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053993479.1	30	Reactome: R-HSA-1170546;Reactome: R-HSA-5610780;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-2122947;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-8939902;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-2894862;Reactome: R-HSA-195253;Reactome: R-HSA-5684264;Reactome: R-HSA-2644607;Reactome: R-HSA-187577;Reactome: R-HSA-917937;Reactome: R-HSA-180534;Reactome: R-HSA-2644606;Reactome: R-HSA-9604323;Reactome: R-HSA-8854050	"Prolactin receptor signaling";"Degradation of GLI1 by the proteasome";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Regulation of RUNX2 expression and activity";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Iron uptake and transport";"Vpu mediated degradation of CD4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Negative regulation of NOTCH4 signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053995109.1	8	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-5689880	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Ub-specific processing proteases"
XP_053972246.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053993232.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_053990739.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053972213.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_053988846.1	24	Reactome: R-HSA-392170;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-500657;Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-416476;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-418217	"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Presynaptic function of Kainate receptors";"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"Glucagon signaling in metabolic regulation";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"G alpha (q) signalling events";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta"
XP_053988813.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053977165.1	10	MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-5826;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-8001;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7559	"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Hypoglycin biosynthesis";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway"
XP_053987022.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053984368.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053988656.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053988561.1	12	Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy"
XP_053978564.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_053990349.1	27	Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749	"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs"
XP_053993723.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053973213.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053991892.1	12	Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2894862;Reactome: R-HSA-9013695	"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription"
XP_053992232.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053973246.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_053979365.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053973937.1	27	Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5250924;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5467340;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;Reactome: R-HSA-8939902;KEGG: 04714+2.7.11.1;Reactome: R-HSA-196299;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75815;Reactome: R-HSA-3371453;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5610783;Reactome: R-HSA-5358752;Reactome: R-HSA-5610785;Reactome: R-HSA-5339716;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4641262;KEGG: 05170+2.7.11.1;Reactome: R-HSA-399956;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348	"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"B-WICH complex positively regulates rRNA expression";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"PI3K-Akt signaling pathway";"AXIN missense mutants destabilize the destruction complex";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Regulation of RUNX2 expression and activity";"Thermogenesis";"Beta-catenin phosphorylation cascade";"Human papillomavirus infection";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of HSF1-mediated heat shock response";"Human cytomegalovirus infection";"Degradation of GLI2 by the proteasome";"T41 mutants of beta-catenin aren't phosphorylated";"GLI3 is processed to GLI3R by the proteasome";"Misspliced GSK3beta mutants stabilize beta-catenin";"mTOR signaling pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Human immunodeficiency virus 1 infection";"CRMPs in Sema3A signaling";"Relaxin signaling pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex"
XP_053983915.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980836.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_053990457.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053983745.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053985321.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053975324.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-6803157	"Neutrophil degranulation";"Antimicrobial peptides"
XP_053979455.1	7	Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-156827;Reactome: R-HSA-72662	"Translation initiation complex formation";"mTORC1-mediated signalling";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S"
XP_053987020.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053975203.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053987323.1	9	Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1362300	"Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_053978355.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053977718.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053970394.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053972636.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053978465.1	1	Reactome: R-HSA-72165	"mRNA Splicing - Minor Pathway"
XP_053978019.1	4	MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis"
XP_053980256.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053977079.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8053;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-7411	"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)"
XP_053983628.1	4	Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198	"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis"
XP_053992230.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis"
XP_053992627.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053989123.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775	"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis"
XP_053979554.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"Hedgehog 'off' state";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_053971731.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_053978778.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053976536.1	3	Reactome: R-HSA-8957275;Reactome: R-HSA-381038;Reactome: R-HSA-381426	"Post-translational protein phosphorylation";"XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_053976585.1	2	Reactome: R-HSA-418890;Reactome: R-HSA-3295583	"Role of second messengers in netrin-1 signaling";"TRP channels"
XP_053979068.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Recycling pathway of L1";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Cilium Assembly"
XP_053973636.1	17	Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5358565	"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)"
XP_053981197.1	14	Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942	"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)"
XP_053990801.1	8	Reactome: R-HSA-113507;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-176187	"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress"
XP_053975190.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053978137.1	5	Reactome: R-HSA-975578;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.68	"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis"
XP_053979182.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053986528.1	24	Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-1445148;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690	"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Gap junction assembly";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events"
XP_053981344.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053977511.1	1	Reactome: R-HSA-5693571	"Nonhomologous End-Joining (NHEJ)"
XP_053972026.1	5	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8856828	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Clathrin-mediated endocytosis"
XP_053971538.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053988957.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053988574.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_053987175.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-8856828	"EGFR downregulation";"Negative regulation of MET activity";"Ub-specific processing proteases";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Clathrin-mediated endocytosis"
XP_053988598.1	3	Reactome: R-HSA-2206296;Reactome: R-HSA-2024101;Reactome: R-HSA-2024096	"MPS II - Hunter syndrome";"CS/DS degradation";"HS-GAG degradation"
XP_053993230.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053982628.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053987227.1	2	Reactome: R-HSA-376176;Reactome: R-HSA-202433	"Signaling by ROBO receptors";"Generation of second messenger molecules"
XP_053975874.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053975307.1	4	MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23	"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_053971388.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_053985613.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053985646.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053990184.1	1	Reactome: R-HSA-71064	"Lysine catabolism"
XP_053992501.1	7	KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61	"Citrate cycle (TCA cycle)";"Lysine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism"
XP_053985920.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053981173.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053982707.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053975048.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053987005.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053980271.1	3	Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160	"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions"
XP_053976745.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053983484.1	33	Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-68877	"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Mitotic Prometaphase"
XP_053986937.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053991936.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053986246.1	18	Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4	"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Ether lipid metabolism";"alpha-Linolenic acid metabolism"
XP_053991316.1	18	Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053991343.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053992708.1	16	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053987984.1	7	Reactome: R-HSA-5693565;Reactome: R-HSA-983168;Reactome: R-HSA-5693571;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Antigen processing: Ubiquitination & Proteasome degradation";"Nonhomologous End-Joining (NHEJ)";"Protein ubiquitination";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends"
XP_053976386.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053974274.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053978556.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053978661.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053971712.1	6	MetaCyc: PWY-7442;Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-5497	"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)"
XP_053979566.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473	"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint"
XP_053985969.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053984009.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_053978409.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053972721.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053986503.1	3	Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17;KEGG: 00240+3.6.1.17	"Detoxification of Reactive Oxygen Species";"Purine metabolism";"Pyrimidine metabolism"
XP_053981189.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053991637.1	10	KEGG: 00051+5.3.1.1;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;KEGG: 00562+5.3.1.1	"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Inositol phosphate metabolism"
XP_053986636.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053985717.1	2	Reactome: R-HSA-3359473;Reactome: R-HSA-196741	"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053985236.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053971163.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053985285.1	4	Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053971710.1	12	Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2979096	"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_053982585.1	12	MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)"
XP_053986448.1	5	MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7177	"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II"
XP_053978698.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053987308.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053981638.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_053987897.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_053985922.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053971085.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053977530.1	8	Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68827	"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex"
XP_053971036.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053981875.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053983536.1	2	Reactome: R-HSA-5250971;Reactome: R-HSA-5682910	"Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions"
XP_053984264.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_053979841.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053980009.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053974261.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053983918.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053979458.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053989120.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053992233.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053980888.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_053991893.1	12	Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408	"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"HATs acetylate histones";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation"
XP_053985241.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053973212.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053992747.1	17	MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00630+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6728;KEGG: 00720+1.1.1.37	"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Partial TCA cycle (obligate autotrophs)";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes"
XP_053973326.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053982541.1	1	Reactome: R-HSA-186797	"Signaling by PDGF"
XP_053993337.1	12	MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-5856;MetaCyc: PWY-5870;MetaCyc: PWY-5872;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5857;MetaCyc: PWY-5871	"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)"
XP_053975200.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053984455.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053987023.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053972500.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053980180.1	6	Reactome: R-HSA-8948216;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8874081	"Collagen chain trimerization";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"MET activates PTK2 signaling"
XP_053993722.1	6	Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-162594;Reactome: R-HSA-174437	"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand"
XP_053984365.1	52	Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167238;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-6803529;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-6782135;Reactome: R-HSA-72203;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-8851708;Reactome: R-HSA-168325	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Transcriptional regulation by small RNAs";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"FGFR2 alternative splicing";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"Dual incision in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis"
XP_053975512.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_053971434.1	6	MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_053974078.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053973544.1	3	Reactome: R-HSA-2151201;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Transcriptional activation of mitochondrial biogenesis";"UCH proteinases";"HATs acetylate histones"
XP_053974094.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053978491.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053984676.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053972212.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-6804758	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation"
XP_053981303.1	56	Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577	"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21"
XP_053993233.1	1	Reactome: R-HSA-6785631	"ERBB2 Regulates Cell Motility"
XP_053993155.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053987872.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053993769.1	3	Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546	"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)"
XP_053974719.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053983338.1	11	Reactome: R-HSA-71403;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-7268;MetaCyc: PWY-6728;MetaCyc: PWY-7124;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;MetaCyc: PWY-7254;KEGG: 00480+1.1.1.42	"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Glutathione metabolism"
XP_053992337.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053971041.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395	"DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER"
XP_053987418.1	5	Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-936964;Reactome: R-HSA-937041	"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1"
XP_053970666.1	24	Reactome: R-HSA-5218920;Reactome: R-HSA-202424;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5674400;Reactome: R-HSA-5607764;Reactome: R-HSA-5625740;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-165158;Reactome: R-HSA-114604;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-6804757	"VEGFR2 mediated vascular permeability";"Downstream TCR signaling";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection";"PIP3 activates AKT signaling";"Human papillomavirus infection";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"FCERI mediated NF-kB activation";"Constitutive Signaling by AKT1 E17K in Cancer";"CLEC7A (Dectin-1) signaling";"RHO GTPases activate PKNs";"Relaxin signaling pathway";"VEGFR2 mediated cell proliferation";"Activation of AKT2";"GPVI-mediated activation cascade";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"RSK activation";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Regulation of TP53 Degradation"
XP_053975895.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_053982959.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053971535.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053991711.1	29	Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Dual incision in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_053971586.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053977080.1	10	MetaCyc: PWY-5667;MetaCyc: PWY-7411;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051	"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_053988595.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter"
XP_053988118.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756	"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation"
XP_053983035.1	3	KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562	"Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria"
XP_053971221.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053985631.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053987870.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053975634.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053989147.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053979391.1	3	MetaCyc: PWY-7511;Reactome: R-HSA-110314;Reactome: R-HSA-8866654	"Protein ubiquitination";"Recognition of DNA damage by PCNA-containing replication complex";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053979183.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053972139.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053972445.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053988276.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053983959.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053989122.1	3	Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359	"Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels"
XP_053979419.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053976588.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053973210.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053978775.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053990994.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053975024.1	2	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Glycerol degradation I"
XP_053985021.1	2	Reactome: R-HSA-2206307;Reactome: R-HSA-2024096	"MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation"
XP_053977715.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053975202.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053990049.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053978468.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656121	"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLI"
XP_053982035.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_053991406.1	3	KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420	"Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)"
XP_053984977.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053987243.1	1	Reactome: R-HSA-446205	"Synthesis of GDP-mannose"
XP_053993616.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053974551.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053983785.1	56	Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785	"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome"
XP_053973286.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053992839.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053984929.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_053973521.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053982313.1	2	Reactome: R-HSA-419812;Reactome: R-HSA-418555	"Calcitonin-like ligand receptors";"G alpha (s) signalling events"
XP_053980962.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Signaling by Hippo";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053982010.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053973153.1	9	MetaCyc: PWY-6703;MetaCyc: PWY-7852;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-7442;MetaCyc: PWY-6983;MetaCyc: PWY-6147	"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I"
XP_053987280.1	8	KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"T cell receptor signaling pathway"
XP_053979658.1	19	Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-202733	"Chylomicron assembly";"Platelet sensitization by LDL";"LDL clearance";"LDL remodeling";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"VLDL clearance";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"Chylomicron remodeling";"Chylomicron clearance";"Scavenging by Class B Receptors";"VLDL assembly";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall"
XP_053974970.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053972728.1	4	Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654	"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053971895.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_053989101.1	3	Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053971510.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053972286.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053982785.1	5	Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379	"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events"
XP_053975586.1	7	Reactome: R-HSA-177929;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232	"Signaling by EGFR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants"
XP_053974268.1	13	MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-2029485;Reactome: R-HSA-9027277;MetaCyc: PWY-8052;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-202433	"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Role of phospholipids in phagocytosis";"Erythropoietin activates Phospholipase C gamma (PLCG)";"2-arachidonoylglycerol biosynthesis";"DAP12 signaling";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Generation of second messenger molecules"
XP_053993218.1	5	KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168	"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)"
XP_053982217.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053982736.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053975535.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985002.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_053988678.1	6	KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Stachyose degradation";"Galactose catabolism"
XP_053981631.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053992176.1	13	KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I"
XP_053978691.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_053988694.1	10	MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2	"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism"
XP_053972521.1	6	KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"Th1 and Th2 cell differentiation";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_053978076.1	1	Reactome: R-HSA-427359	"SIRT1 negatively regulates rRNA expression"
XP_053986703.1	2	Reactome: R-HSA-426117;Reactome: R-HSA-5619039	"Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)"
XP_053984845.1	5	KEGG: 00860+4.1.1.37;MetaCyc: PWY-7159;Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7766	"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)"
XP_053983010.1	3	Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654	"Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053992680.1	1	MetaCyc: PWY-6938	"NADH repair"
XP_053970291.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053978756.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053975434.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053985999.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-5221030	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA"
XP_053985431.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053972855.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053984116.1	3	Reactome: R-HSA-5358565;Reactome: R-HSA-5632928;Reactome: R-HSA-5632968	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6"
XP_053985000.1	2	Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_053982425.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053992508.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053983507.1	4	MetaCyc: PWY-7511;Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144	"Protein ubiquitination";"IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation"
XP_053971193.1	5	Reactome: R-HSA-9033500;MetaCyc: PWY-7782;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896	"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis"
XP_053970356.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053975041.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053994125.1	13	Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-2871809;Reactome: R-HSA-381676	"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"Ca2+ pathway";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion"
XP_053992682.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053993701.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053981241.1	5	Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-380994	"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053987867.1	1	Reactome: R-HSA-196819	"Vitamin B1 (thiamin) metabolism"
XP_053971244.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52	"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation"
XP_053972488.1	2	MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4	"Cellulose degradation II (fungi)";"Starch and sucrose metabolism"
XP_053979275.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_053993443.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)"
XP_053972645.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053980960.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053992701.1	15	Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593	"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity"
XP_053984278.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_053983425.1	4	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_053974291.1	2	Reactome: R-HSA-8866907;Reactome: R-HSA-8866904	"Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors"
XP_053984294.1	1	MetaCyc: PWY-7379	"Mrna capping II"
XP_053985638.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053977890.1	9	Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695	"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation"
XP_053988111.1	5	Reactome: R-HSA-189451;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188	"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)"
XP_053973681.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053992014.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053979398.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053990805.1	19	Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-389359;Reactome: R-HSA-525793;Reactome: R-HSA-182971;Reactome: R-HSA-3928662;Reactome: R-HSA-5625970;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-8950505;Reactome: R-HSA-983231;Reactome: R-HSA-5663220;Reactome: R-HSA-418885;Reactome: R-HSA-5627123;Reactome: R-HSA-194840	"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"CD28 dependent Vav1 pathway";"Myogenesis";"EGFR downregulation";"EPHB-mediated forward signaling";"RHO GTPases activate KTN1";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate Formins";"DCC mediated attractive signaling";"RHO GTPases activate PAKs";"Rho GTPase cycle"
XP_053975085.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053989371.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053986152.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053995027.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053970558.1	2	KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217	"Purine metabolism";"Purine salvage"
XP_053987171.1	10	Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-9636383;Reactome: R-HSA-432720;Reactome: R-HSA-917729	"Negative regulation of MET activity";"Ub-specific processing proteases";"Inhibition of membrane repair";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053986238.1	15	Reactome: R-HSA-5689896;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340	"Ovarian tumor domain proteases";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex"
XP_053977198.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053992306.1	29	Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-3108214;Reactome: R-HSA-174437;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782135;Reactome: R-HSA-3371511;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5696395;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-110314	"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Removal of the Flap Intermediate from the C-strand";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Dual incision in TC-NER";"HSF1 activation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLI";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Formation of Incision Complex in GG-NER";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053995042.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053984061.1	34	Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5578749;Reactome: R-HSA-9639288;Reactome: R-HSA-159227;Reactome: R-HSA-170822	"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transcriptional regulation by small RNAs";"Amino acids regulate mTORC1";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_053993014.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053973702.1	2	Reactome: R-HSA-2393930;MetaCyc: PWY-6502	"Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I"
XP_053988464.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053980395.1	9	KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12	"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis"
XP_053992520.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053975904.1	8	KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1	"Starch and sucrose metabolism";"Glycolysis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_053988354.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053974997.1	13	MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2160916;Reactome: R-HSA-1660662;MetaCyc: PWY-6902	"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"CS/DS degradation";"Hyaluronan uptake and degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)"
XP_053981947.1	1	Reactome: R-HSA-389977	"Post-chaperonin tubulin folding pathway"
XP_053986584.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053982896.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025	"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation"
XP_053993306.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053985028.1	7	KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-7586	"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation"
XP_053973700.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053982331.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_053994103.1	1	Reactome: R-HSA-69273	"Cyclin A/B1/B2 associated events during G2/M transition"
XP_053988565.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events"
XP_053993569.1	2	Reactome: R-HSA-1236974;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane"
XP_053980074.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053982403.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053989454.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053985325.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053970884.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053985248.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_053983741.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053973744.1	9	Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237	"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2"
XP_053987399.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_053975942.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053987706.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053982548.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053993547.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053981856.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053983403.1	3	Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259	"Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism"
XP_053981920.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053981646.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053975927.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053972700.1	2	KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921	"Histidine metabolism";"Histidine catabolism"
XP_053977414.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053987411.1	7	Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids"
XP_053976428.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053986150.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053973334.1	5	KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171	"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis"
XP_053984098.1	11	Reactome: R-HSA-72163;Reactome: R-HSA-9013695;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2173796;Reactome: R-HSA-210744	"mRNA Splicing - Major Pathway";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_053971979.1	3	Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053974071.1	7	Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300	"Polo-like kinase mediated events";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"
XP_053970519.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_053991165.1	29	Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-75953	"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation"
XP_053981438.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053986858.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053983548.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053972914.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053982911.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053973457.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053980601.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053978242.1	4	Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346	"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis"
XP_053978889.1	11	Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001	"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade"
XP_053994317.1	6	MetaCyc: PWY-6987;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599	"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency"
XP_053973367.1	6	Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint"
XP_053990213.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053970640.1	5	Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221	"RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway"
XP_053983652.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_053976181.1	16	Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-179409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A"
XP_053982965.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053986184.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053988863.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053983827.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053987778.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_053984938.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053987794.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053973349.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053988079.1	13	Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802952;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"mTOR signaling pathway";"Thermogenesis";"Signaling by BRAF and RAF fusions";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053980318.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053993075.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053974232.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053985492.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053987137.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053986552.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053983842.1	6	Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053975811.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053974640.1	1	KEGG: 00970+6.1.1.19	"Aminoacyl-tRNA biosynthesis"
XP_053974723.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053994937.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508	"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis"
XP_053980420.1	4	Reactome: R-HSA-5661270;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;KEGG: 00040+2.7.1.17	"Formation of xylulose-5-phosphate";"Glycerol degradation I";"Glycerolipid metabolism";"Pentose and glucuronate interconversions"
XP_053993828.1	7	MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-6351	"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053994246.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053973263.1	1	Reactome: R-HSA-977443	"GABA receptor activation"
XP_053978175.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053979059.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053974604.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053983965.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053989337.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053984601.1	25	Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-380270;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833	"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Recruitment of mitotic centrosome proteins and complexes";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Cilium Assembly"
XP_053972975.1	9	Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-112043	"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events"
XP_053970627.1	4	KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260;Reactome: R-HSA-4720489	"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG12 causes ALG12-CDG (CDG-1g)"
XP_053988437.1	83	Reactome: R-HSA-1433559;Reactome: R-HSA-9645135;Reactome: R-HSA-8856828;Reactome: R-HSA-9028335;Reactome: R-HSA-5654710;Reactome: R-HSA-8853334;Reactome: R-HSA-5654689;Reactome: R-HSA-512988;Reactome: R-HSA-8851805;Reactome: R-HSA-8875360;Reactome: R-HSA-74749;Reactome: R-HSA-182971;Reactome: R-HSA-5654704;Reactome: R-HSA-9026519;Reactome: R-HSA-5655291;Reactome: R-HSA-2219530;Reactome: R-HSA-5654720;Reactome: R-HSA-912526;Reactome: R-HSA-167044;Reactome: R-HSA-5654695;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-112412;Reactome: R-HSA-375165;Reactome: R-HSA-5637810;Reactome: R-HSA-9027284;Reactome: R-HSA-912631;Reactome: R-HSA-180292;Reactome: R-HSA-1257604;Reactome: R-HSA-8856825;Reactome: R-HSA-5654726;Reactome: R-HSA-5655302;Reactome: R-HSA-210993;Reactome: R-HSA-8853338;Reactome: R-HSA-8851907;Reactome: R-HSA-388841;Reactome: R-HSA-5654727;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-389359;Reactome: R-HSA-5654732;Reactome: R-HSA-5655253;Reactome: R-HSA-9034864;Reactome: R-HSA-180336;Reactome: R-HSA-391160;Reactome: R-HSA-5654699;Reactome: R-HSA-5654688;Reactome: R-HSA-74751;Reactome: R-HSA-9634285;Reactome: R-HSA-8853659;Reactome: R-HSA-5654700;Reactome: R-HSA-179812;Reactome: R-HSA-109704;Reactome: R-HSA-186763;Reactome: R-HSA-2179392;Reactome: R-HSA-9664565;Reactome: R-HSA-5654712;Reactome: R-HSA-2428933;Reactome: R-HSA-2730905;Reactome: R-HSA-5654719;Reactome: R-HSA-9607240;Reactome: R-HSA-2424491;Reactome: R-HSA-1295596;Reactome: R-HSA-1250347;Reactome: R-HSA-9028731;Reactome: R-HSA-1839117;Reactome: R-HSA-983695;Reactome: R-HSA-2029482;Reactome: R-HSA-5654693;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-5654733;Reactome: R-HSA-5654706;Reactome: R-HSA-6807004;Reactome: R-HSA-8983432;Reactome: R-HSA-5663213;Reactome: R-HSA-1963640;Reactome: R-HSA-1236382;Reactome: R-HSA-8865999;Reactome: R-HSA-8875656;Reactome: R-HSA-1433557;Reactome: R-HSA-8875555;Reactome: R-HSA-354194	"Regulation of KIT signaling";"STAT5 Activation";"Clathrin-mediated endocytosis";"Activated NTRK2 signals through PI3K";"PI-3K cascade:FGFR3";"Signaling by FGFR3 fusions in cancer";"PI-3K cascade:FGFR1";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"MET activates RAS signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"Signal attenuation";"EGFR downregulation";"SHC-mediated cascade:FGFR3";"Activated NTRK2 signals through RAS";"Signaling by FGFR4 in disease";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI-3K cascade:FGFR4";"Interleukin receptor SHC signaling";"Signalling to RAS";"PI-3K cascade:FGFR2";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"SOS-mediated signalling";"NCAM signaling for neurite out-growth";"Constitutive Signaling by EGFRvIII";"Erythropoietin activates RAS";"Regulation of signaling by CBL";"GAB1 signalosome";"PIP3 activates AKT signaling";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR1 signaling";"Signaling by FGFR1 in disease";"Tie2 Signaling";"Signaling by FGFR3 point mutants in cancer";"MET activates PI3K/AKT signaling";"Costimulation by the CD28 family";"Negative regulation of FGFR2 signaling";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"CD28 dependent Vav1 pathway";"Negative regulation of FGFR3 signaling";"Signaling by FGFR2 in disease";"Activated NTRK3 signals through RAS";"SHC1 events in EGFR signaling";"Signal regulatory protein family interactions";"SHC-mediated cascade:FGFR2";"SHC-mediated cascade:FGFR1";"Insulin receptor signalling cascade";"Constitutive Signaling by Overexpressed ERBB2";"RET signaling";"FRS-mediated FGFR2 signaling";"GRB2 events in EGFR signaling";"PI3K Cascade";"Downstream signal transduction";"EGFR Transactivation by Gastrin";"Signaling by ERBB2 KD Mutants";"FRS-mediated FGFR4 signaling";"SHC-related events triggered by IGF1R";"Role of LAT2/NTAL/LAB on calcium mobilization";"SHC-mediated cascade:FGFR4";"FLT3 Signaling";"DAP12 signaling";"Spry regulation of FGF signaling";"SHC1 events in ERBB4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"Signaling by cytosolic FGFR1 fusion mutants";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of actin dynamics for phagocytic cup formation";"FRS-mediated FGFR1 signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"Negative regulation of FGFR4 signaling";"FRS-mediated FGFR3 signaling";"Negative regulation of MET activity";"Interleukin-15 signaling";"RHO GTPases Activate WASPs and WAVEs";"GRB2 events in ERBB2 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"MET activates PTPN11";"MET receptor recycling";"Signaling by SCF-KIT";"MET activates RAP1 and RAC1";"GRB2:SOS provides linkage to MAPK signaling for Integrins"
XP_053974037.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053992169.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053989482.1	2	KEGG: 00970+6.1.1.14;Reactome: R-HSA-2151201	"Aminoacyl-tRNA biosynthesis";"Transcriptional activation of mitochondrial biogenesis"
XP_053986550.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053984015.1	1	Reactome: R-HSA-5689896	"Ovarian tumor domain proteases"
XP_053978069.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053993122.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-204005	"RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport"
XP_053992755.1	2	Reactome: R-HSA-425397;Reactome: R-HSA-5619061	"Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)"
XP_053981692.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983148.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053988083.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053978632.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_053978047.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053984447.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053975996.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053983273.1	4	Reactome: R-HSA-72086;Reactome: R-HSA-167160;MetaCyc: PWY-7375;Reactome: R-HSA-77075	"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_053993755.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053975793.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053994636.1	7	KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_053977656.1	8	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053970483.1	3	MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482	"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)"
XP_053988165.1	9	Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6794361;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932	"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Neurexins and neuroligins";"EPHB-mediated forward signaling";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules"
XP_053991471.1	14	Reactome: R-HSA-9634638;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2173788;Reactome: R-HSA-450520;Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444	"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Downregulation of TGF-beta receptor signaling";"HuR (ELAVL1) binds and stabilizes mRNA";"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053983650.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_053974852.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053980469.1	2	KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis"
XP_053980015.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053974230.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053980359.1	3	Reactome: R-HSA-6783310;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Fanconi Anemia Pathway";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053981677.1	9	Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724	"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Macroautophagy";"mTOR signalling";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription"
XP_053979504.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053985117.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053976653.1	1	Reactome: R-HSA-2995383	"Initiation of Nuclear Envelope Reformation"
XP_053971472.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053971239.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053978305.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053987695.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053976077.1	1	Reactome: R-HSA-8850843	"Phosphate bond hydrolysis by NTPDase proteins"
XP_053975467.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053989708.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053991678.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053981350.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053994641.1	1	Reactome: R-HSA-77289	"Mitochondrial Fatty Acid Beta-Oxidation"
XP_053973553.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053974705.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983124.1	3	Reactome: R-HSA-4086398;Reactome: R-HSA-392517;Reactome: R-HSA-418457	"Ca2+ pathway";"Rap1 signalling";"cGMP effects"
XP_053993576.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053982093.1	9	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism"
XP_053979527.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_053981462.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053992654.1	16	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-5693554	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053991133.1	9	Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-191859	"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"snRNP Assembly"
XP_053981352.1	3	Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053995159.1	4	Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394	"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER"
XP_053980543.1	17	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6790901;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"rRNA modification in the nucleus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053980516.1	14	MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51	"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism"
XP_053991255.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_053989211.1	5	Reactome: R-HSA-3270619;Reactome: R-HSA-3134975;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695	"IRF3-mediated induction of type I IFN";"Regulation of innate immune responses to cytosolic DNA";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Neutrophil degranulation"
XP_053993844.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053979214.1	4	KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731;MetaCyc: PWY-4361;MetaCyc: PWY-7174	"Cysteine and methionine metabolism";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II"
XP_053990784.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053970587.1	6	KEGG: 00562+3.1.3.66;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;MetaCyc: PWY-6368	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation"
XP_053993108.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053984699.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556	"Insulin receptor recycling";"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes"
XP_053990231.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053981429.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053979196.1	4	Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3	"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism"
XP_053990407.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053983390.1	3	Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828	"MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis"
XP_053971470.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053988606.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053992108.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053983107.1	3	MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892	"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)"
XP_053985477.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053986994.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053976439.1	1	Reactome: R-HSA-1362409	"Mitochondrial iron-sulfur cluster biogenesis"
XP_053986978.1	14	KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053	"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II"
XP_053992844.1	1	Reactome: R-HSA-2129379	"Molecules associated with elastic fibres"
XP_053977709.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053986823.1	1	Reactome: R-HSA-2564830	"Cytosolic iron-sulfur cluster assembly"
XP_053989014.1	2	Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2	"Glycine degradation";"Glycine, serine and threonine metabolism"
XP_053987106.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053995066.1	10	MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;MetaCyc: PWY-5667	"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis I"
XP_053976060.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053988559.1	12	Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436	"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic"
XP_053975470.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053977761.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053976453.1	5	Reactome: R-HSA-2022857;Reactome: R-HSA-6798695;KEGG: 00531+3.1.6.14;Reactome: R-HSA-2206305;Reactome: R-HSA-432720	"Keratan sulfate degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"MPS IIID - Sanfilippo syndrome D";"Lysosome Vesicle Biogenesis"
XP_053987764.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053978902.1	2	Reactome: R-HSA-3214815;Reactome: R-HSA-427413	"HDACs deacetylate histones";"NoRC negatively regulates rRNA expression"
XP_053991159.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053972144.1	5	MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22	"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycerolipid metabolism";"Sphingolipid metabolism"
XP_053975667.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053991812.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053985976.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053987051.1	6	MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;MetaCyc: PWY-6123;Reactome: R-HSA-73817;KEGG: 00230+4.1.1.21	"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism"
XP_053991478.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053992199.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053994607.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985460.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053980311.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053970314.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053981039.1	14	Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-418217;Reactome: R-HSA-434316;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;Reactome: R-HSA-4086398;MetaCyc: PWY-7039;Reactome: R-HSA-500657;Reactome: R-HSA-399997	"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"G beta:gamma signalling through PLC beta";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Inositol phosphate metabolism";"G alpha (q) signalling events";"Ca2+ pathway";"Phosphatidate metabolism, as a signaling molecule";"Presynaptic function of Kainate receptors";"Acetylcholine regulates insulin secretion"
XP_053984931.1	3	Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion"
XP_053984499.1	4	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_053987771.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053991810.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053976029.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980608.1	5	KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344	"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)"
XP_053988941.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053972102.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053988406.1	3	KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109	"Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis"
XP_053974006.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053971186.1	18	KEGG: 00983+2.7.4.6;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7224;MetaCyc: PWY-7197	"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"CMP phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation"
XP_053987594.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053980931.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_053971253.1	4	KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801	"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion"
XP_053986125.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876	"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing"
XP_053984311.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053974314.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_053975472.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053972539.1	9	Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201	"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis"
XP_053975818.1	2	Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3	"Platelet degranulation";"Aminoacyl-tRNA biosynthesis"
XP_053988985.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-7218;MetaCyc: PWY-6901	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation"
XP_053988733.1	3	Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277	"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)"
XP_053990238.1	10	Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6798695;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756	"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"WNT mediated activation of DVL";"Neutrophil degranulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation"
XP_053974679.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053974215.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053973657.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053972869.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053972370.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053994584.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053984946.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053984743.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_053984620.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053992101.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053980620.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053983883.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053978430.1	1	Reactome: R-HSA-880009	"Interconversion of 2-oxoglutarate and 2-hydroxyglutarate"
XP_053984030.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053987376.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053994152.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813	"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids"
XP_053986971.1	3	Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5	"Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism"
XP_053977132.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053973847.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053978001.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053976998.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402	"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex"
XP_053983329.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053972822.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053994238.1	17	KEGG: 00061+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5744;KEGG: 00640+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00620+6.4.1.2	"Fatty acid biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Propanoate metabolism";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Pyruvate metabolism"
XP_053985692.1	4	Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-6802952;Reactome: R-HSA-983168	"Macroautophagy";"Neutrophil degranulation";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053988222.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053988316.1	1	Reactome: R-HSA-499943	"Interconversion of nucleotide di- and triphosphates"
XP_053977258.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053992265.1	16	MetaCyc: PWY-7124;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-2221;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-8004;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-5723;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-1042	"Ethylene biosynthesis V (engineered)";"Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)"
XP_053979332.1	2	KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019	"Pyrimidine metabolism";"Pseudouridine degradation"
XP_053980622.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053994150.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053977130.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053984647.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053990485.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053981814.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053970427.1	3	Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760	"RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation"
XP_053977838.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1"
XP_053971697.1	2	MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6	"Methylglyoxal degradation I";"Pyruvate metabolism"
XP_053988220.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053988637.1	1	Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis"
XP_053983185.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_053987950.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_053992776.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053987826.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053979910.1	5	Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225	"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin"
XP_053983360.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_053983879.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053981589.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053983063.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053974427.1	11	Reactome: R-HSA-4420097;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007	"VEGFA-VEGFR2 Pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"Relaxin signaling pathway";"Human papillomavirus infection";"p38MAPK events"
XP_053988027.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642	"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_053994485.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-72163;Reactome: R-HSA-6811434	"Kinesins";"mRNA Splicing - Major Pathway";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053980647.1	1	Reactome: R-HSA-428890	"Role of ABL in ROBO-SLIT signaling"
XP_053979704.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053986097.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-163282	"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation"
XP_053977366.1	3	Reactome: R-HSA-9033807;MetaCyc: PWY-7831;MetaCyc: PWY-7833	"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)"
XP_053972372.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053982136.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053970683.1	12	Reactome: R-HSA-418885;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1	"DCC mediated attractive signaling";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human papillomavirus infection";"Thermogenesis";"G alpha (q) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway"
XP_053970505.1	3	Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153	"eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis"
XP_053976961.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053982185.1	2	KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142	"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis"
XP_053991671.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050	"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053984622.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_053975435.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053972854.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053991282.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053991849.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053978251.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053982424.1	1	Reactome: R-HSA-196741	"Cobalamin (Cbl, vitamin B12) transport and metabolism"
XP_053981336.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053979803.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053972421.1	5	Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER"
XP_053993206.1	9	KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;Reactome: R-HSA-156590	"Glutathione metabolism";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione conjugation"
XP_053984576.1	2	Reactome: R-HSA-3769402;Reactome: R-HSA-201722	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053981385.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053978396.1	12	MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-3801;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9	"Sucrose biosynthesis II";"Stachyose degradation";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism"
XP_053991867.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053977008.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053973644.1	42	Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-3214858;Reactome: R-HSA-9609690;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-427413;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-2559582;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-110328;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-912446;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815	"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"RMTs methylate histone arginines";"HCMV Early Events";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NoRC negatively regulates rRNA expression";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"Condensation of Prophase Chromosomes";"HCMV Late Events";"DNA methylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Meiotic recombination";"Estrogen-dependent gene expression";"Meiotic synapsis";"HDACs deacetylate histones"
XP_053994124.1	13	Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-422356;Reactome: R-HSA-139853;Reactome: R-HSA-5218921	"PLC beta mediated events";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Regulation of insulin secretion";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation"
XP_053971172.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053990124.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053983851.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053971987.1	7	Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053985980.1	7	Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61	"Lysine catabolism";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_053994392.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053981916.1	1	Reactome: R-HSA-433137	"Sodium-coupled sulphate, di- and tri-carboxylate transporters"
XP_053981943.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053979298.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling"
XP_053980576.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981713.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053972644.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053981868.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053975149.1	5	MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268	"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053986338.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053984295.1	1	KEGG: 00970+6.1.1.3	"Aminoacyl-tRNA biosynthesis"
XP_053973781.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053970841.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053983784.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053994093.1	2	KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20	"Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism"
XP_053985982.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_053974651.1	4	Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546	"Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling"
XP_053991301.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053989990.1	2	Reactome: R-HSA-8866654;Reactome: R-HSA-9033241	"E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import"
XP_053981162.1	3	KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348	"Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition"
XP_053982407.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5696394	"UCH proteinases";"DNA Damage Recognition in GG-NER"
XP_053982231.1	2	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis"
XP_053986959.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053978831.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)"
XP_053973588.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053982784.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_053986625.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897	"Regulation of PTEN mRNA translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes"
XP_053973602.1	16	Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944	"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2"
XP_053972781.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053984800.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053991280.1	8	Reactome: R-HSA-9636467;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-167590;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Blockage of phagosome acidification";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Nef Mediated CD4 Down-regulation";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053992516.1	7	MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226;MetaCyc: PWY-6352;MetaCyc: PWY-7625	"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Synthesis of PI";"3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)"
XP_053979496.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_053971686.1	8	KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00350+1.14.16.2;Reactome: R-HSA-209905;MetaCyc: PWY-5049;MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5394	"Folate biosynthesis";"(S)-reticuline biosynthesis I";"Tyrosine metabolism";"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Betalamic acid biosynthesis"
XP_053984108.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053976139.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053985348.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053993699.1	9	Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953	"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation"
XP_053983407.1	2	Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053990390.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981088.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053979261.1	5	MetaCyc: PWY-7180;KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;MetaCyc: PWY-8060;Reactome: R-HSA-6798695	"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation"
XP_053971170.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053975923.1	2	KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10	"Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis"
XP_053974458.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_053988058.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053981809.1	3	Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053985861.1	1	Reactome: R-HSA-5657655	"MGMT-mediated DNA damage reversal"
XP_053988564.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444	"Aggrephagy";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053979825.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053982317.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-419812	"G alpha (s) signalling events";"Calcitonin-like ligand receptors"
XP_053980075.1	2	Reactome: R-HSA-8949215;Reactome: R-HSA-8949664	"Mitochondrial calcium ion transport";"Processing of SMDT1"
XP_053978561.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053973157.1	9	MetaCyc: PWY-6147;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7852;MetaCyc: PWY-6703;MetaCyc: PWY-7442;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-5664	"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Erythro-tetrahydrobiopterin biosynthesis II"
XP_053985324.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053970885.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053975321.1	3	Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases"
XP_053977204.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053983213.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053986707.1	2	Reactome: R-HSA-5619039;Reactome: R-HSA-426117	"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters"
XP_053979078.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053980828.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053987437.1	16	Reactome: R-HSA-5602680;Reactome: R-HSA-209543;Reactome: R-HSA-6811558;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-975155;Reactome: R-HSA-1257604;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-5603037;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-1236974;Reactome: R-HSA-5603041;Reactome: R-HSA-975110;Reactome: R-HSA-3134963	"MyD88 deficiency (TLR5)";"p75NTR recruits signalling complexes";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"MyD88 dependent cascade initiated on endosome";"PIP3 activates AKT signaling";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"IRAK4 deficiency (TLR5)";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"ER-Phagosome pathway";"IRAK4 deficiency (TLR2/4)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"
XP_053977415.1	6	Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001	"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade"
XP_053973335.1	13	Reactome: R-HSA-2160916;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52	"Hyaluronan uptake and degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation"
XP_053987380.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053978846.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_053987083.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053991164.1	29	Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex"
XP_053970368.1	2	Reactome: R-HSA-3295583;Reactome: R-HSA-418890	"TRP channels";"Role of second messengers in netrin-1 signaling"
XP_053982246.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053994652.1	7	KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22	"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_053992601.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053972915.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053977047.1	7	Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_053990842.1	1	Reactome: R-HSA-5358493	"Synthesis of diphthamide-EEF2"
XP_053989888.1	12	Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220	"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins"
XP_053970458.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053980120.1	10	KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis IV (plant cytosol)"
XP_053987511.1	9	Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928	"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG degradation";"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis"
XP_053992359.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053978115.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053976528.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053971344.1	7	Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472	"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"HCMV Early Events";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053981341.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053992469.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053983503.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053971197.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053984755.1	2	Reactome: R-HSA-877300;Reactome: R-HSA-2132295	"Interferon gamma signaling";"MHC class II antigen presentation"
XP_053975084.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053987382.1	11	Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_053984147.1	3	KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1	"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism"
XP_053985898.1	5	Reactome: R-HSA-8856825;Reactome: R-HSA-917937;Reactome: R-HSA-8951664;Reactome: R-HSA-5689603;Reactome: R-HSA-2173789	"Cargo recognition for clathrin-mediated endocytosis";"Iron uptake and transport";"Neddylation";"UCH proteinases";"TGF-beta receptor signaling activates SMADs"
XP_053977227.1	1	Reactome: R-HSA-1614517	"Sulfide oxidation to sulfate"
XP_053975871.1	3	MetaCyc: PWY-7159;Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3	"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053978598.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053992447.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053982026.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_053988571.1	12	Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_053984378.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_053979758.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053982685.1	1	Reactome: R-HSA-350562	"Regulation of ornithine decarboxylase (ODC)"
XP_053976721.1	6	MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656	"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis"
XP_053993015.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_053980378.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_053988019.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053975905.1	8	KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis"
XP_053970391.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053977889.1	9	Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608	"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Platelet degranulation"
XP_053988355.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053972038.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053971526.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053992422.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053971281.1	1	Reactome: R-HSA-427975	"Proton/oligopeptide cotransporters"
XP_053980755.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053986585.1	5	Reactome: R-HSA-389661;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895;MetaCyc: PWY-5046	"Glyoxylate metabolism and glycine degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA"
XP_053991537.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053979551.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"G alpha (z) signalling events";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state"
XP_053973628.1	1	Reactome: R-HSA-70350	"Fructose catabolism"
XP_053987079.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053970256.1	5	Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-5250924	"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression"
XP_053970766.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport"
XP_053970963.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053987027.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053980989.1	1	Reactome: R-HSA-3000178	"ECM proteoglycans"
XP_053974658.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053970848.1	2	Reactome: R-HSA-8876198;Reactome: R-HSA-8873719	"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation"
XP_053985284.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053984056.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053978456.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053973932.1	3	Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766	"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion"
XP_053979970.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053992913.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053992716.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_053992237.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053985731.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation"
XP_053983238.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex"
XP_053975734.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053980101.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053983725.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053985341.1	2	Reactome: R-HSA-5632681;Reactome: R-HSA-5635838	"Ligand-receptor interactions";"Activation of SMO"
XP_053977279.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053981081.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053970658.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events"
XP_053981190.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053973226.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053993913.1	2	Reactome: R-HSA-6782315;MetaCyc: PWY-6829	"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)"
XP_053971871.1	5	Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport"
XP_053981874.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053972932.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053993946.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053978838.1	5	Reactome: R-HSA-111457;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-9627069	"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity"
XP_053987220.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053993620.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III"
XP_053993237.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_053975003.1	13	MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52	"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation"
XP_053974766.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053984265.1	1	MetaCyc: PWY-7437	"Protein O-[N-acetyl]-glucosylation"
XP_053985538.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053972788.1	2	Reactome: R-HSA-373752;Reactome: R-HSA-525793	"Netrin-1 signaling";"Myogenesis"
XP_053987042.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053974596.1	1	Reactome: R-HSA-211945	"Phase I - Functionalization of compounds"
XP_053976700.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053990185.1	3	Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213	"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs"
XP_053994063.1	1	Reactome: R-HSA-111957	"Cam-PDE 1 activation"
XP_053982150.1	1	MetaCyc: PWY-7533	"Gliotoxin biosynthesis"
XP_053979187.1	3	Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053978132.1	6	Reactome: R-HSA-8957275;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-201722;Reactome: R-HSA-3769402	"Post-translational protein phosphorylation";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex"
XP_053981192.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-383280	"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway"
XP_053987004.1	1	Reactome: R-HSA-975957	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053983648.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813	"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids"
XP_053989143.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053986741.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053976744.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053993622.1	4	MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;Reactome: R-HSA-71737	"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Glyphosate degradation III";"Pyrophosphate hydrolysis"
XP_053978258.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053980973.1	11	Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-68962;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400	"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Activation of the pre-replicative complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER"
XP_053983485.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-3232118	"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of transcription factors"
XP_053982858.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053991984.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053987936.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053979356.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053981861.1	1	Reactome: R-HSA-5685939	"HDR through MMEJ (alt-NHEJ)"
XP_053978509.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_053987269.1	3	MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757	"Folate polyglutamylation";"Folate biosynthesis";"Metabolism of folate and pterines"
XP_053982485.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053983858.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053972621.1	7	Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711	"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events"
XP_053986933.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053980555.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_053975878.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053986736.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053986217.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-2151201	"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis"
XP_053979751.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053971534.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053991322.1	18	Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167158	"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"mRNA Capping";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex"
XP_053983441.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053975412.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053981531.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_053978591.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053988594.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053981348.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053976521.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053982906.1	13	Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053975635.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482	"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation"
XP_053971923.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053985617.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053981177.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053971610.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053972444.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053991459.1	3	Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394	"Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER"
XP_053977900.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053989061.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053978798.1	2	MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1	"S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism"
XP_053985162.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053978774.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053990995.1	6	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;MetaCyc: PWY-7511;Reactome: R-HSA-6782210;Reactome: R-HSA-72163	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Protein ubiquitination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway"
XP_053975025.1	2	MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30	"Glycerol degradation I";"Glycerolipid metabolism"
XP_053993580.1	22	Reactome: R-HSA-2467813;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558	"Separation of Sister Chromatids";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RAF activation";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling"
XP_053991870.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053979558.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053991369.1	5	Reactome: R-HSA-6798695;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;KEGG: 00240+3.6.1.6	"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyrimidine metabolism"
XP_053987711.1	2	Reactome: R-HSA-6802953;Reactome: R-HSA-5658442	"RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs"
XP_053995087.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053977714.1	6	MetaCyc: PWY-6922;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6344;MetaCyc: PWY-4981;KEGG: 00330+2.6.1.13	"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism"
XP_053991178.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053977944.1	7	KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219	"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_053970374.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053986346.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053983906.1	14	MetaCyc: PWY-2201;MetaCyc: PWY-5497;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-1622;KEGG: 00630+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-3841;Reactome: R-HSA-196757;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;KEGG: 00460+2.1.2.1	"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glyoxylate and dicarboxylate metabolism";"Photorespiration ";"Folate transformations II (plants)";"Metabolism of folate and pterines";"One carbon pool by folate";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Cyanoamino acid metabolism"
XP_053984199.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053987208.1	6	MetaCyc: PWY-5743;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5789	"3-hydroxypropanoate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle"
XP_053975987.1	2	Reactome: R-HSA-936837;Reactome: R-HSA-6798695	"Ion transport by P-type ATPases";"Neutrophil degranulation"
XP_053985713.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053971167.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053991872.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-1362409	"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis"
XP_053993582.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-195253;Reactome: R-HSA-5675221;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-196299	"RAF activation";"Degradation of beta-catenin by the destruction complex";"Negative regulation of MAPK pathway";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Beta-catenin phosphorylation cascade"
XP_053985916.1	11	Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-2979096	"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"NOTCH2 Activation and Transmission of Signal to the Nucleus"
XP_053979519.1	2	Reactome: R-HSA-1268020;Reactome: R-HSA-611105	"Mitochondrial protein import";"Respiratory electron transport"
XP_053992499.1	7	MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_053986507.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053991506.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053984454.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053971149.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_053984364.1	52	Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-73776;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-6803529;Reactome: R-HSA-73780;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-8851708;Reactome: R-HSA-168325;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73863;Reactome: R-HSA-427413	"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"FGFR2 alternative splicing";"RNA Polymerase III Chain Elongation";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Signaling by FGFR2 IIIa TM";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression"
XP_053971435.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053973545.1	3	Reactome: R-HSA-2151201;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847	"Transcriptional activation of mitochondrial biogenesis";"UCH proteinases";"HATs acetylate histones"
XP_053993499.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053974095.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053971486.1	3	Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis"
XP_053970451.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053991320.1	18	Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053989881.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053975410.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053988106.1	5	MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-189451	"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Heme biosynthesis"
XP_053993154.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053989074.1	3	KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261	"Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I"
XP_053980821.1	27	Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-159236	"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053979071.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053989098.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053973402.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053988764.1	4	KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191	"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC"
XP_053978761.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053987893.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange"
XP_053984747.1	2	Reactome: R-HSA-4641265;Reactome: R-HSA-5339700	"Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP"
XP_053982262.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053984233.1	6	Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813	"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids"
XP_053983229.1	7	Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;MetaCyc: PWY-7980;Reactome: R-HSA-1268020	"Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"ATP biosynthesis";"Mitochondrial protein import"
XP_053989420.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053970315.1	8	KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-5481;Reactome: R-HSA-70268;MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27	"Propanoate metabolism";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism"
XP_053972077.1	10	Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-438066	"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Trafficking of AMPA receptors";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation"
XP_053980722.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053990866.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053993091.1	29	Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-113418	"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex"
XP_053993888.1	6	Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex"
XP_053988322.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053984769.1	1	Reactome: R-HSA-429947	"Deadenylation of mRNA"
XP_053982887.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053979850.1	1	Reactome: R-HSA-437239	"Recycling pathway of L1"
XP_053977468.1	5	Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6	"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"UTP and CTP dephosphorylation I";"Purine metabolism"
XP_053992455.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053971797.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053979232.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053992365.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053977358.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053988737.1	1	Reactome: R-HSA-417973	"Adenosine P1 receptors"
XP_053988216.1	8	KEGG: 05163+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053972653.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053988347.1	2	Reactome: R-HSA-983168;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation"
XP_053992180.1	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis"
XP_053982229.1	11	Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Estrogen-dependent gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053978829.1	4	Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-1799339	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane"
XP_053979723.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053992676.1	56	Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813	"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids"
XP_053973968.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053978383.1	4	KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50;Reactome: R-HSA-351202;MetaCyc: PWY-6834	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Spermidine biosynthesis III"
XP_053988178.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053987595.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053983262.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-110314;Reactome: R-HSA-174411	"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere"
XP_053985529.1	19	Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8957275;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-381426	"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class A Receptors";"LDL remodeling";"Platelet sensitization by LDL";"Chylomicron assembly";"LDL clearance";"VLDL assembly";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Chylomicron clearance";"Scavenging by Class B Receptors";"Post-translational protein phosphorylation";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)"
XP_053990338.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053978080.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_053984480.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053970783.1	11	Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955	"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation"
XP_053994866.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053987118.1	4	Reactome: R-HSA-8934903;Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685	"Receptor Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy"
XP_053988369.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053974315.1	4	Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878	"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport"
XP_053980747.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053989601.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053983887.1	13	Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-416993;Reactome: R-HSA-5099900	"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"MHC class II antigen presentation";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4"
XP_053980233.1	2	Reactome: R-HSA-1483191;Reactome: R-HSA-425366	"Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds"
XP_053992888.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053975570.1	13	Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825	"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis"
XP_053975493.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053993455.1	5	Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2	"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_053992182.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053974779.1	4	KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1	"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism"
XP_053987494.1	5	KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;Reactome: R-HSA-450341	"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors"
XP_053970423.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-4090294	"Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors"
XP_053971693.1	6	MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6606	"Guanosine nucleotides degradation III";"Purine metabolism";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II"
XP_053988506.1	5	Reactome: R-HSA-5635838;Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-373080	"Activation of SMO";"Hedgehog 'off' state";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)"
XP_053982049.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053989015.1	7	Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-171319;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"DNA Damage Recognition in GG-NER";"UCH proteinases";"Telomere Extension By Telomerase";"HATs acetylate histones"
XP_053988633.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_053972439.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053987159.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053977266.1	2	Reactome: R-HSA-6799198;Reactome: R-HSA-611105	"Complex I biogenesis";"Respiratory electron transport"
XP_053993977.1	3	Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004	"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity"
XP_053989447.1	6	Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_053980599.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053973757.1	26	Reactome: R-HSA-9018519;Reactome: R-HSA-1234158;Reactome: R-HSA-5617472;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-933541;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-210744;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-201722;Reactome: R-HSA-918233;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-3371568;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408;Reactome: R-HSA-5621575;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-3134973;Reactome: R-HSA-3214847	"Estrogen-dependent gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Circadian Clock";"RORA activates gene expression";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Attenuation phase";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation";"CD209 (DC-SIGN) signaling";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"HATs acetylate histones"
XP_053974687.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053988418.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053974018.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053982067.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053980616.1	16	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053980720.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053984853.1	10	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Human immunodeficiency virus 1 infection";"RSK activation";"Human papillomavirus infection";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection"
XP_053971567.1	9	Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-674695	"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events"
XP_053988320.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053989780.1	13	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053979852.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053983067.1	4	Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase"
XP_053988023.1	6	Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053974423.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053979230.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053971549.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053994086.1	4	Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085	"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin"
XP_053982552.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053972297.1	2	Reactome: R-HSA-877312;Reactome: R-HSA-6807004	"Regulation of IFNG signaling";"Negative regulation of MET activity"
XP_053988308.1	2	Reactome: R-HSA-1483148;Reactome: R-HSA-1483166	"Synthesis of PG";"Synthesis of PA"
XP_053993271.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_053984501.1	4	Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762	"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation"
XP_053981473.1	4	Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814	"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes"
XP_053981590.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053994707.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053990484.1	2	KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053981815.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053986652.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962	"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex"
XP_053991826.1	56	Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751	"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity"
XP_053986827.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_053976349.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053980708.1	5	Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends"
XP_053976739.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053971770.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053986842.1	6	Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-201722	"RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex"
XP_053992992.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053971052.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053995137.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_053976263.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053980501.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053982184.1	4	KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258	"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis"
XP_053988984.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053978981.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053978109.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053971772.1	2	Reactome: R-HSA-5223345;Reactome: R-HSA-425393	"Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides"
XP_053986148.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053985057.1	3	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation"
XP_053994585.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053994603.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053991376.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053971463.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053982550.1	2	Reactome: R-HSA-749476;Reactome: R-HSA-73980	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination"
XP_053979587.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053986273.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053989516.1	42	Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5693565;Reactome: R-HSA-3214841;Reactome: R-HSA-977225;Reactome: R-HSA-427359;Reactome: R-HSA-2559582;Reactome: R-HSA-201722;Reactome: R-HSA-5693571;Reactome: R-HSA-171306;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-2559580;Reactome: R-HSA-5625886;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-110331;Reactome: R-HSA-73772;Reactome: R-HSA-3214847;Reactome: R-HSA-110328;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-9018519;Reactome: R-HSA-912446;Reactome: R-HSA-3214815;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-9610379;Reactome: R-HSA-5334118;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-2559586	"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PKMTs methylate histone lysines";"Amyloid fiber formation";"SIRT1 negatively regulates rRNA expression";"Senescence-Associated Secretory Phenotype (SASP)";"Formation of the beta-catenin:TCF transactivating complex";"Nonhomologous End-Joining (NHEJ)";"Packaging Of Telomere Ends";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"Oxidative Stress Induced Senescence";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"HCMV Early Events";"RMTs methylate histone arginines";"Cleavage of the damaged purine";"RNA Polymerase I Promoter Escape";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Estrogen-dependent gene expression";"Meiotic recombination";"HDACs deacetylate histones";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"HCMV Late Events";"DNA methylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence"
XP_053975919.1	12	Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-5620912	"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"Anchoring of the basal body to the plasma membrane"
XP_053985250.1	4	Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_053980211.1	2	Reactome: R-HSA-6782315;Reactome: R-HSA-6787450	"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion"
XP_053981146.1	3	Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916	"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium"
XP_053975767.1	4	Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219	"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_053992264.1	2	Reactome: R-HSA-8869496;Reactome: R-HSA-1268020	"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import"
XP_053995058.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053972974.1	9	KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-7039;MetaCyc: PWY-6351	"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"G alpha (q) signalling events";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053981832.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053989580.1	2	Reactome: R-HSA-2682334;Reactome: R-HSA-3928665	"EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells"
XP_053986362.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053970579.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050	"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053974011.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053984014.1	1	Reactome: R-HSA-1614635	"Sulfur amino acid metabolism"
XP_053978414.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053990896.1	5	Reactome: R-HSA-3214815;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053975257.1	8	Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-164378;Reactome: R-HSA-432040	"PKA activation";"DARPP-32 events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins"
XP_053992754.1	6	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-73856	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination"
XP_053984799.1	5	MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;KEGG: 00900+2.7.4.2;MetaCyc: PWY-922	"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I"
XP_053984306.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053990684.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053971767.1	2	Reactome: R-HSA-425393;Reactome: R-HSA-5223345	"Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events"
XP_053980306.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053992061.1	2	KEGG: 00983+3.6.1.23;KEGG: 00240+3.6.1.23	"Drug metabolism - other enzymes";"Pyrimidine metabolism"
XP_053993754.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053984520.1	3	Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561	"Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers"
XP_053983971.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053980799.1	4	Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053973557.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053976847.1	26	Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-190840	"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Recycling pathway of L1";"Gap junction assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane"
XP_053988164.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_053978161.1	4	Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662	"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling"
XP_053981057.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434	"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053988399.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_053971339.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053980014.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053975050.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053987464.1	27	Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168276;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638	"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NS1 Mediated Effects on Host Pathways";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins"
XP_053977461.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053990741.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053984522.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers"
XP_053980547.1	24	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9646399;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"Gap junction assembly";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Aggrephagy";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins"
XP_053994403.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053977351.1	1	Reactome: R-HSA-189451	"Heme biosynthesis"
XP_053981689.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053982964.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053975052.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053986185.1	3	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_053993098.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint"
XP_053987795.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053993074.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053985729.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053978515.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257	"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion"
XP_053976128.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053981830.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053991778.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053977114.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053979006.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053985815.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_053971597.1	56	Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5610780	"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome"
XP_053981252.1	4	Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;MetaCyc: PWY-5642	"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"2,4-dinitrotoluene degradation"
XP_053992881.1	8	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053983103.1	7	Reactome: R-HSA-5368598;Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262	"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"TCF dependent signaling in response to WNT";"PCP/CE pathway";"WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane"
XP_053979314.1	6	Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265	"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes"
XP_053983097.1	10	Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022699	"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates neuronal receptors and channels"
XP_053974605.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053994911.1	57	Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints"
XP_053983964.1	2	KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024	"Purine metabolism";"DARPP-32 events"
XP_053978198.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053974912.1	2	KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1	"Pentose phosphate pathway";"Purine metabolism"
XP_053983823.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5628897	"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes"
XP_053980680.1	3	Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053984218.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-5628897	"Respiratory electron transport";"TP53 Regulates Metabolic Genes"
XP_053977668.1	17	Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053975567.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_053982072.1	57	Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978	"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)"
XP_053970727.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053976808.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053976397.1	3	Reactome: R-HSA-5083627;Reactome: R-HSA-2022854;Reactome: R-HSA-5173105	"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis";"O-linked glycosylation"
XP_053994313.1	6	Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382;Reactome: R-HSA-196780;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987	"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin transport and metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)"
XP_053995106.1	2	Reactome: R-HSA-72165;Reactome: R-HSA-72163	"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053988282.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.5	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053991254.1	2	Reactome: R-HSA-432722;Reactome: R-HSA-432720	"Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis"
XP_053990785.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053989716.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_053975549.1	2	Reactome: R-HSA-418990;Reactome: R-HSA-5218920	"Adherens junctions interactions";"VEGFR2 mediated vascular permeability"
XP_053978342.1	5	Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-197264	"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging"
XP_053994933.1	14	MetaCyc: PWY-6142;KEGG: 00010+4.2.1.11;MetaCyc: PWY-5723;MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00680+4.2.1.11;MetaCyc: PWY-1622;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-7124;MetaCyc: PWY-2221;MetaCyc: PWY-7218;MetaCyc: PWY-8004;MetaCyc: PWY-6901	"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"Rubisco shunt";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Methane metabolism";"Formaldehyde assimilation I (serine pathway)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Ethylene biosynthesis V (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation"
XP_053979404.1	27	Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5619107	"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"ISG15 antiviral mechanism";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)"
XP_053994785.1	8	Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Mitotic Prometaphase"
XP_053988659.1	6	KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;Reactome: R-HSA-70370	"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALT can cause Galactosemia";"Stachyose degradation";"Galactose catabolism"
XP_053973267.1	30	Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210	"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER"
XP_053980839.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053974727.1	2	Reactome: R-HSA-5620924;Reactome: R-HSA-5610787	"Intraflagellar transport";"Hedgehog 'off' state"
XP_053984176.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053986995.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053994524.1	6	MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;Reactome: R-HSA-9640463	"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis"
XP_053971572.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053984680.1	6	Reactome: R-HSA-8963889;Reactome: R-HSA-8957275;Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-381426;Reactome: R-HSA-8874211	"Assembly of active LPL and LIPC lipase complexes";"Post-translational protein phosphorylation";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"CREB3 factors activate genes"
XP_053992845.1	9	KEGG: 00564+1.1.1.94;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411	"Glycerophospholipid metabolism";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)"
XP_053972060.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053987886.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053972639.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053973188.1	7	Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270	"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes"
XP_053979505.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053984416.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053983373.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053978043.1	6	Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471	"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053981529.1	1	Reactome: R-HSA-70171	"Glycolysis"
XP_053992116.1	10	MetaCyc: PWY-6372;MetaCyc: PWY-6361;MetaCyc: PWY-6554;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6362;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol"
XP_053988618.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053982277.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053993278.1	8	Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_053984508.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053977691.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053970740.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053980259.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053983752.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053988433.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053985577.1	1	Reactome: R-HSA-196843	"Vitamin B2 (riboflavin) metabolism"
XP_053974033.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053972062.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053975951.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053980682.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594	"Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events"
XP_053974623.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_053972188.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing"
XP_053982070.1	20	Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-174411;Reactome: R-HSA-110314	"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053980508.1	13	MetaCyc: PWY-7254;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-8086;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-561;MetaCyc: PWY-6969;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-5913	"TCA cycle VII (acetate-producers)";"Pyruvate metabolism";"Methylaspartate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)"
XP_053991695.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053989857.1	7	Reactome: R-HSA-2691232;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606	"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053974704.1	1	Reactome: R-HSA-5693565	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053983125.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_053984701.1	5	Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977	"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling"
XP_053989622.1	17	Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-8951664	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation"
XP_053972029.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980416.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053992278.1	14	MetaCyc: PWY-7782;MetaCyc: PWY-8053;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51	"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism"
XP_053994507.1	1	Reactome: R-HSA-162658	"Golgi Cisternae Pericentriolar Stack Reorganization"
XP_053975797.1	2	Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053972141.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053986267.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053991266.1	5	Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3	"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism"
XP_053975462.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053979520.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_053991491.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053986249.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053970580.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053977051.1	7	Reactome: R-HSA-606279;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_053987054.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053989579.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053994400.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053983293.1	16	Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5749;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.4;KEGG: 00020+6.2.1.5	"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Itaconate degradation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citrate cycle (TCA cycle)"
XP_053989011.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053977495.1	6	Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-912446	"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Meiotic recombination"
XP_053978893.1	3	MetaCyc: PWY-6829;MetaCyc: PWY-7888;Reactome: R-HSA-6782315	"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol"
XP_053985859.1	27	Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-1169408	"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"ISG15 antiviral mechanism"
XP_053981833.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053978559.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053971477.1	3	MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3	"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis"
XP_053978195.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053980151.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6791226	"tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053993824.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053985110.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053980523.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053975789.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_053985239.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053984314.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053983102.1	7	Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220;Reactome: R-HSA-201688;Reactome: R-HSA-4086400;Reactome: R-HSA-201681;Reactome: R-HSA-5368598	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"RHO GTPases Activate Formins";"WNT mediated activation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins"
XP_053976125.1	1	Reactome: R-HSA-8854214	"TBC/RABGAPs"
XP_053978518.1	8	KEGG: 00010+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1	"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis"
XP_053974311.1	4	Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-5673001	"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade"
XP_053979547.1	11	Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594	"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events"
XP_053975053.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053984934.1	1	Reactome: R-HSA-6785807	"Interleukin-4 and Interleukin-13 signaling"
XP_053981357.1	3	Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)"
XP_053980314.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053975350.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053971039.1	3	KEGG: 00860+2.5.1.141;MetaCyc: PWY-7856;Reactome: R-HSA-189451	"Porphyrin and chlorophyll metabolism";"Heme a biosynthesis";"Heme biosynthesis"
XP_053987798.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_053976373.1	13	MetaCyc: PWY-7210;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_053986188.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053979522.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053978941.1	9	Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-3656535;Reactome: R-HSA-2173789;Reactome: R-HSA-3656532;Reactome: R-HSA-5689603	"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 LBD Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"TGFBR1 KD Mutants in Cancer";"UCH proteinases"
XP_053988944.1	2	Reactome: R-HSA-9020702;Reactome: R-HSA-6798695	"Interleukin-1 signaling";"Neutrophil degranulation"
XP_053983539.1	3	Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955	"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation"
XP_053994402.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053973329.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053988001.1	1	Reactome: R-HSA-209968	"Thyroxine biosynthesis"
XP_053980215.1	2	Reactome: R-HSA-8951664;Reactome: R-HSA-983168	"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053992848.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053983847.1	4	Reactome: R-HSA-1268020;Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453	"Mitochondrial protein import";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Regulation of HSF1-mediated heat shock response"
XP_053986557.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053976292.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053976971.1	7	KEGG: 00670+1.5.1.3;MetaCyc: PWY-6614;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;Reactome: R-HSA-1474151;Reactome: R-HSA-196757;MetaCyc: PWY-3841	"One carbon pool by folate";"Tetrahydrofolate biosynthesis";"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Metabolism of folate and pterines";"Folate transformations II (plants)"
XP_053974030.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053990581.1	3	MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65	"Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism"
XP_053992104.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053971490.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053974333.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053978040.1	6	Reactome: R-HSA-3299685;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241	"Detoxification of Reactive Oxygen Species";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import"
XP_053983370.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053978343.1	5	MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695	"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation"
XP_053990226.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends"
XP_053982657.1	2	Reactome: R-HSA-418555;Reactome: R-HSA-444821	"G alpha (s) signalling events";"Relaxin receptors"
XP_053992766.1	11	Reactome: R-HSA-4043916;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-6992;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881	"Defective MPI causes MPI-CDG (CDG-1b)";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"1,5-anhydrofructose degradation";"Mannitol degradation II";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis"
XP_053992963.1	12	Reactome: R-HSA-400253;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-68877;Reactome: R-HSA-141444;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2467813;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788	"Circadian Clock";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Separation of Sister Chromatids";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling"
XP_053989727.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_053994932.1	12	KEGG: 00010+6.2.1.1;KEGG: 00620+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-5132;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5133;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Lupulone and humulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Adlupulone and adhumulone biosynthesis";"Colupulone and cohumulone biosynthesis";"Cis-genanyl-coa degradation";"Propanoate metabolism"
XP_053979839.1	4	KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726	"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation"
XP_053994312.1	6	KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;MetaCyc: PWY-7382	"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)"
XP_053993104.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053972329.1	5	KEGG: 00270+4.2.1.109;Reactome: R-HSA-111458;MetaCyc: PWY-4361;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069	"Cysteine and methionine metabolism";"Formation of apoptosome";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway";"Regulation of the apoptosome activity"
XP_053990788.1	3	Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438	"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic"
XP_053979218.1	16	Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152	"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Neddylation";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053993766.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_053974743.1	6	Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568	"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053974913.1	2	KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"Purine metabolism";"Pentose phosphate pathway"
XP_053983822.1	5	Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-111447	"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria"
XP_053994581.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053982869.1	16	MetaCyc: PWY-5723;KEGG: 00010+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7124;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7218;MetaCyc: PWY-2221;Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Rubisco shunt";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Ethylene biosynthesis V (engineered)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Gluconeogenesis"
XP_053982073.1	1	Reactome: R-HSA-111465	"Apoptotic cleavage of cellular proteins"
XP_053992658.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053983657.1	3	Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681	"Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT"
XP_053977665.1	18	KEGG: 00250+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00710+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;MetaCyc: PWY-6638;KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00960+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7383	"Alanine, aspartate and glutamate metabolism";"Isoquinoline alkaloid biosynthesis";"(R)-cysteate degradation";"Carbon fixation in photosynthetic organisms";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine and proline metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)"
XP_053984215.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053992275.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_053994046.1	4	Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053982956.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053984427.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053990930.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053993596.1	8	MetaCyc: PWY-7268;MetaCyc: PWY-6855;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;KEGG: 00030+1.1.1.49;MetaCyc: PWY-5514;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004	"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glutathione metabolism";"Entner-Doudoroff pathway I"
XP_053989623.1	17	Reactome: R-HSA-174184;Reactome: R-HSA-8951664;Reactome: R-HSA-176412;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-179409	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Neddylation";"Phosphorylation of the APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A"
XP_053974622.1	6	Reactome: R-HSA-3769402;Reactome: R-HSA-8951664;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841	"Deactivation of the beta-catenin transactivating complex";"Neddylation";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines"
XP_053976964.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053987456.1	1	Reactome: R-HSA-419771	"Opsins"
XP_053991698.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053972136.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053980505.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053983820.1	29	Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167246	"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Dual incision in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript"
XP_053989704.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053976097.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053970647.1	14	MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5972;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602	"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Fatty acid elongation";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)"
XP_053981811.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_053972450.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053976290.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053972063.1	8	MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9609736	"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Assembly and cell surface presentation of NMDA receptors"
XP_053994428.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053983956.1	22	MetaCyc: PWY-5659;MetaCyc: PWY-621;MetaCyc: PWY-5514;KEGG: 00010+5.3.1.9;KEGG: 00500+5.3.1.9;Reactome: R-HSA-70171;Reactome: R-HSA-6798695;Reactome: R-HSA-70263;MetaCyc: PWY-5054;Reactome: R-HSA-5628897;MetaCyc: PWY-6981;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-7347;KEGG: 00520+5.3.1.9;MetaCyc: PWY-8013;KEGG: 00030+5.3.1.9;MetaCyc: PWY-622;MetaCyc: PWY-7385;MetaCyc: PWY-6992;MetaCyc: PWY-5384;MetaCyc: PWY-6142	"GDP-mannose biosynthesis";"Sucrose degradation III (sucrose invertase)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Glycolysis";"Neutrophil degranulation";"Gluconeogenesis";"D-sorbitol biosynthesis I";"TP53 Regulates Metabolic Genes";"Chitin biosynthesis";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Sucrose biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Pentose phosphate pathway";"Starch biosynthesis";"1,3-propanediol biosynthesis (engineered)";"1,5-anhydrofructose degradation";"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)"
XP_053993275.1	8	Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_053974032.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053984683.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053979416.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053983753.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053984442.1	11	Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-5610787	"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (s) signalling events";"G alpha (z) signalling events";"Adenylate cyclase inhibitory pathway";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state"
XP_053978042.1	6	Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389957	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053991409.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053983372.1	1	Reactome: R-HSA-373753	"Nephrin family interactions"
XP_053982089.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_053993619.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053979508.1	14	Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9018519;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897	"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"Estrogen-dependent gene expression";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes"
XP_053990046.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053994930.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053973289.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053985811.1	18	Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409	"Acyl chain remodelling of PI";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)"
XP_053980850.1	1	Reactome: R-HSA-1474151	"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"
XP_053970782.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053970938.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053994157.1	17	Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-2559585;Reactome: R-HSA-2173796;Reactome: R-HSA-2559580;Reactome: R-HSA-111448;Reactome: R-HSA-1362300;Reactome: R-HSA-1912408;Reactome: R-HSA-139915;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-113501;Reactome: R-HSA-69231;Reactome: R-HSA-9616222	"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Oncogene Induced Senescence";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Oxidative Stress Induced Senescence";"Activation of NOXA and translocation to mitochondria";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Pre-NOTCH Transcription and Translation";"Activation of PUMA and translocation to mitochondria";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"G1/S-Specific Transcription";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin D associated events in G1";"Transcriptional regulation of granulopoiesis"
XP_053975492.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053980232.1	2	Reactome: R-HSA-425366;Reactome: R-HSA-1483191	"Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC"
XP_053983739.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053974601.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053977571.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053984604.1	1	MetaCyc: PWY-6829	"Trna methylation (yeast)"
XP_053994745.1	8	KEGG: 00010+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;Reactome: R-HSA-70268;MetaCyc: PWY-8086;MetaCyc: PWY-5481;KEGG: 00640+1.1.1.27;KEGG: 00270+1.1.1.27	"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Propanoate metabolism";"Cysteine and methionine metabolism"
XP_053990335.1	6	MetaCyc: PWY-7234;MetaCyc: PWY-6123;MetaCyc: PWY-6124;KEGG: 00230+4.3.2.2;KEGG: 00250+4.3.2.2;MetaCyc: PWY-7219	"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis"
XP_053972652.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053983263.1	20	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Translesion synthesis by POLI";"Polymerase switching";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER"
XP_053982349.1	5	KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;MetaCyc: PWY-8010;KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347	"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Serine biosynthesis"
XP_053988630.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_053978382.1	4	MetaCyc: PWY-6834;Reactome: R-HSA-351202;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50	"Spermidine biosynthesis III";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism"
XP_053979722.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053988020.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053982739.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053989783.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053983367.1	5	MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822	"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)"
XP_053977355.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053991575.1	4	Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295	"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation"
XP_053979747.1	3	Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis"
XP_053972289.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053979233.1	1	Reactome: R-HSA-5620922	"BBSome-mediated cargo-targeting to cilium"
XP_053992458.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_053979155.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_053987791.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053984232.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase"
XP_053974938.1	3	Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation"
XP_053986393.1	4	Reactome: R-HSA-196741;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011;Reactome: R-HSA-3359462	"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1"
XP_053972965.1	3	KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823	"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053984850.1	1	Reactome: R-HSA-6803204	"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release"
XP_053992179.1	13	KEGG: 00230+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-6545;MetaCyc: PWY-7198;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943	"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053980723.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053985563.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053980640.1	1	Reactome: R-HSA-532668	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053991474.1	6	Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706	"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053988022.1	6	Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053984119.1	11	Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-69473;Reactome: R-HSA-5693568	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053974422.1	4	KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268	"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)"
XP_053979853.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053980483.1	5	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-427413;Reactome: R-HSA-5334118	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"DNA methylation"
XP_053983975.1	2	Reactome: R-HSA-8854518;Reactome: R-HSA-6804756	"AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation"
XP_053987656.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053978759.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053992065.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053985996.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053984230.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053970359.1	3	Reactome: R-HSA-202433;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482	"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation"
XP_053978201.1	1	Reactome: R-HSA-6811438	"Intra-Golgi traffic"
XP_053970469.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053972377.1	1	Reactome: R-HSA-6809371	"Formation of the cornified envelope"
XP_053984852.1	10	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"RSK activation";"PI3K-Akt signaling pathway";"Recycling pathway of L1";"Relaxin signaling pathway";"Human papillomavirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human cytomegalovirus infection"
XP_053986092.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-390471	"Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053980642.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053991609.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053976550.1	2	Reactome: R-HSA-5694530;Reactome: R-HSA-204005	"Cargo concentration in the ER";"COPII-mediated vesicle transport"
XP_053974015.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053988415.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053972273.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053970780.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_053975573.1	5	KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109	"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis"
XP_053984037.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053989779.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053988047.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053974447.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053992183.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053989687.1	7	KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-8964539;MetaCyc: PWY-5921;Reactome: R-HSA-210500	"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutamate and glutamine metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle"
XP_053983801.1	22	Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5675221;Reactome: R-HSA-141444;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5358752;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5467337	"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of MAPK pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"T41 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants have impaired AXIN binding"
XP_053992391.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"ATP biosynthesis";"Insulin receptor recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport"
XP_053972650.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053988632.1	2	Reactome: R-HSA-2032785;Reactome: R-HSA-8951671	"YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription"
XP_053994628.1	7	KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.16	"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism"
XP_053987475.1	6	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex"
XP_053978380.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053980119.1	10	KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484;Reactome: R-HSA-70171	"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis"
XP_053975039.1	1	Reactome: R-HSA-399956	"CRMPs in Sema3A signaling"
XP_053994600.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053983899.1	7	MetaCyc: PWY-5129;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7836;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838	"Sphingolipid biosynthesis (plants)";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis"
XP_053992309.1	56	Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-4641258;Reactome: R-HSA-180585	"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G"
XP_053984705.1	2	Reactome: R-HSA-1237112;Reactome: R-HSA-8950505	"Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"
XP_053992796.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053975662.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053986653.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69091	"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching"
XP_053980705.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053976229.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053987831.1	5	Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026	"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)"
XP_053977834.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053989504.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053971677.1	6	MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6606	"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II"
XP_053993993.1	16	Reactome: R-HSA-174154;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-2559582;Reactome: R-HSA-174084	"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C"
XP_053975955.1	6	Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052	"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state"
XP_053986270.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053982553.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053977695.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053988305.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20	"Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism"
XP_053981472.1	4	Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216	"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen chain trimerization"
XP_053981239.1	5	Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994	"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053977254.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053993566.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053987251.1	1	Reactome: R-HSA-6814848	"Glycerophospholipid catabolism"
XP_053995055.1	2	KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661	"Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis"
XP_053988921.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053976978.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053987709.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053986272.1	1	Reactome: R-HSA-1296061	"HCN channels"
XP_053981859.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053976994.1	2	KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859	"Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053973107.1	2	Reactome: R-HSA-446203;Reactome: R-HSA-1799339	"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053975477.1	5	MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18	"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism"
XP_053990588.1	13	Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7226;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222	"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II"
XP_053981470.1	4	Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216	"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization"
XP_053971352.1	1	Reactome: R-HSA-389957	"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053970408.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053971462.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053992651.1	16	Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-5693554;Reactome: R-HSA-201722;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942	"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Formation of the beta-catenin:TCF transactivating complex";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)"
XP_053994602.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053972093.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053972107.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-532668	"Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"
XP_053990234.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053979211.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053971773.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053975660.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053985535.1	7	KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1	"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway"
XP_053975002.1	13	KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52	"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series"
XP_053972217.1	5	Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-3214815	"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones"
XP_053972933.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053986621.1	14	Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-203927;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700;Reactome: R-HSA-9018519;Reactome: R-HSA-426496	"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs"
XP_053988817.1	4	Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-196108;Reactome: R-HSA-211976	"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis";"Endogenous sterols"
XP_053993912.1	2	Reactome: R-HSA-5628897;Reactome: R-HSA-611105	"TP53 Regulates Metabolic Genes";"Respiratory electron transport"
XP_053987016.1	1	Reactome: R-HSA-418990	"Adherens junctions interactions"
XP_053978835.1	5	Reactome: R-HSA-9627069;Reactome: R-HSA-111469;Reactome: R-HSA-111463;Reactome: R-HSA-111464;Reactome: R-HSA-111457	"Regulation of the apoptosome activity";"SMAC, XIAP-regulated apoptotic response";"SMAC (DIABLO) binds to IAPs";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria"
XP_053987043.1	7	KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277	"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis"
XP_053978886.1	11	Reactome: R-HSA-9664565;Reactome: R-HSA-6785631;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1257604	"Signaling by ERBB2 KD Mutants";"ERBB2 Regulates Cell Motility";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"PIP3 activates AKT signaling"
XP_053982235.1	1	Reactome: R-HSA-1971475	"A tetrasaccharide linker sequence is required for GAG synthesis"
XP_053980970.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053972524.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053976703.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053992332.1	5	Reactome: R-HSA-4755579;MetaCyc: PWY-6129;KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate"
XP_053988076.1	2	Reactome: R-HSA-8866654;MetaCyc: PWY-7511	"E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination"
XP_053989963.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053989140.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053978694.1	1	Reactome: R-HSA-427652	"Sodium-coupled phosphate cotransporters"
XP_053975224.1	4	Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606	"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants"
XP_053985221.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053992727.1	57	Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577	"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21"
XP_053987304.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981634.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053974929.1	16	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053990453.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053991305.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053986444.1	3	Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053973217.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053970845.1	1	Reactome: R-HSA-388844	"Receptor-type tyrosine-protein phosphatases"
XP_053973933.1	3	Reactome: R-HSA-8868766;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470	"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion"
XP_053979056.1	1	Reactome: R-HSA-9037629	"Lewis blood group biosynthesis"
XP_053983153.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053977280.1	11	Reactome: R-HSA-975634;Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3656237;Reactome: R-HSA-202733;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3560783	"Retinoid metabolism and transport";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective EXT2 causes exostoses 2";"Cell surface interactions at the vascular wall";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B4GALT7 causes EDS, progeroid type"
XP_053989658.1	17	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053970962.1	7	MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-4702	"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Phytate degradation I"
XP_053994249.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053976034.1	8	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-6804115;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053978066.1	10	Reactome: R-HSA-2122947;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-210744	"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells"
XP_053982488.1	2	Reactome: R-HSA-5689603;Reactome: R-HSA-5689880	"UCH proteinases";"Ub-specific processing proteases"
XP_053989127.1	3	Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837	"Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases"
XP_053992623.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053983855.1	1	Reactome: R-HSA-8876725	"Protein methylation"
XP_053981244.1	14	Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110312	"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Polymerase switching";"Translesion synthesis by REV1"
XP_053971241.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053974294.1	2	Reactome: R-HSA-8866904;Reactome: R-HSA-8866907	"Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors"
XP_053990639.1	3	MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661	"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis"
XP_053991921.1	3	Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-72163	"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway"
XP_053973425.1	1	Reactome: R-HSA-1855231	"Synthesis of IPs in the ER lumen"
XP_053989619.1	14	Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-1632852;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Macroautophagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_053977282.1	13	Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053970960.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51	"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation"
XP_053994880.1	1	MetaCyc: PWY-7942	"5-oxo-L-proline metabolism"
XP_053993330.1	5	Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825	"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis"
XP_053977659.1	1	Reactome: R-HSA-71384	"Ethanol oxidation"
XP_053975000.1	13	Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52	"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series"
XP_053983488.1	2	Reactome: R-HSA-5576893;Reactome: R-HSA-5576892	"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation"
XP_053993910.1	2	Reactome: R-HSA-8949613;Reactome: R-HSA-163210	"Cristae formation";"Formation of ATP by chemiosmotic coupling"
XP_053970294.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053984187.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053980291.1	6	MetaCyc: PWY-5269;MetaCyc: PWY-5668;Reactome: R-HSA-1483148;MetaCyc: PWY-7817;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166	"Cardiolipin biosynthesis II";"Cardiolipin biosynthesis I";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Synthesis of PA"
XP_053994639.1	6	Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+4.1.1.33;Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-446199	"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Synthesis of Dolichyl-phosphate"
XP_053975044.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053993704.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053983645.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053980356.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053981381.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053981193.1	17	Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167290;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16	"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Th1 and Th2 cell differentiation";"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053973507.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053980466.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053988351.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-983168	"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053975189.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053971969.1	2	Reactome: R-HSA-212676;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053975901.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053986312.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053979555.1	11	Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170670	"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway"
XP_053975028.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053971717.1	7	Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69231	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1"
XP_053972896.1	1	Reactome: R-HSA-264876	"Insulin processing"
XP_053971947.1	3	Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11	"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism"
XP_053980751.1	3	Reactome: R-HSA-445989;Reactome: R-HSA-933542;Reactome: R-HSA-1810476	"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1"
XP_053985710.1	7	Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171	"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions"
XP_053970754.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053985626.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5610780	"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome"
XP_053979371.1	22	MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7049;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7035;MetaCyc: PWY-7726;MetaCyc: PWY-6958;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-5353;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-7592	"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)"
XP_053974754.1	1	Reactome: R-HSA-8866654	"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053989398.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053985036.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053983681.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053978111.1	1	KEGG: 00480+3.4.11.1	"Glutathione metabolism"
XP_053988114.1	10	Reactome: R-HSA-8939243;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6814122	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Neutrophil degranulation";"Synthesis of PC";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053975638.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053971922.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053987174.1	10	Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-5689880;Reactome: R-HSA-9635644;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-9636383;Reactome: R-HSA-8856828	"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Ub-specific processing proteases";"Inhibition of membrane repair";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"Prevention of phagosomal-lysosomal fusion";"Clathrin-mediated endocytosis"
XP_053975875.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053980558.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053975413.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053991323.1	18	Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246	"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript"
XP_053976150.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_053995156.1	11	KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1	"Relaxin signaling pathway";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Human cytomegalovirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis"
XP_053987414.1	7	Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2467813	"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids"
XP_053985927.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053971646.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053971920.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482	"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events"
XP_053992583.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053984696.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053976648.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053980071.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053984519.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis"
XP_053991047.1	20	Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5696397;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135	"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Polymerase switching";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER"
XP_053981426.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053982334.1	2	Reactome: R-HSA-983231;Reactome: R-HSA-8949215	"Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport"
XP_053986310.1	5	Reactome: R-HSA-376172;Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24	"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"mTOR signaling pathway"
XP_053979364.1	1	KEGG: 00760+2.3.1.286	"Nicotinate and nicotinamide metabolism"
XP_053983914.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053991873.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_053993583.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221	"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway"
XP_053983744.1	2	Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism"
XP_053970881.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053989451.1	6	Reactome: R-HSA-913709;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;Reactome: R-HSA-5083632	"O-linked glycosylation of mucins";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)"
XP_053977399.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053979454.1	7	Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053985712.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053986335.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_053984274.1	7	Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-76071	"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter"
XP_053991387.1	10	Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167172	"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome"
XP_053980803.1	19	Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-3000497;Reactome: R-HSA-5686938;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8964041;Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-8963888	"VLDL assembly";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Chylomicron clearance";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Scavenging by Class H Receptors";"Regulation of TLR by endogenous ligand";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"LDL remodeling";"LDL clearance";"Platelet sensitization by LDL";"Chylomicron assembly"
XP_053973707.1	4	KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;Reactome: R-HSA-212300	"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"DNA methylation";"PRC2 methylates histones and DNA"
XP_053985426.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053995047.1	3	Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862	"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK"
XP_053994393.1	1	Reactome: R-HSA-432722	"Golgi Associated Vesicle Biogenesis"
XP_053990297.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053991430.1	1	Reactome: R-HSA-6804756	"Regulation of TP53 Activity through Phosphorylation"
XP_053994181.1	1	Reactome: R-HSA-5221030	"TET1,2,3 and TDG demethylate DNA"
XP_053994090.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053979295.1	6	Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430;Reactome: R-HSA-4411364	"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling";"Binding of TCF/LEF:CTNNB1 to target gene promoters"
XP_053995069.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053988556.1	12	Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_053981942.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053988661.1	6	Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187	"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress"
XP_053994909.1	57	Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-6798695;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813	"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Neutrophil degranulation";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids"
XP_053972484.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053982481.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053978664.1	14	MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8052;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;Reactome: R-HSA-75109;KEGG: 00565+3.1.3.4;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969	"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Triglyceride biosynthesis";"Ether lipid metabolism";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina"
XP_053986157.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053991156.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053987532.1	4	Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69205;Reactome: R-HSA-68962	"Unwinding of DNA";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription";"Activation of the pre-replicative complex"
XP_053979802.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053992504.1	7	MetaCyc: PWY-5084;Reactome: R-HSA-71403;Reactome: R-HSA-389661;Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citric acid cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine catabolism";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_053971173.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053975920.1	6	Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413	"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression"
XP_053994297.1	5	MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2	"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism"
XP_053983481.1	33	Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159230;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-68877;Reactome: R-HSA-1169408	"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP Dependant Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Mitotic Prometaphase";"ISG15 antiviral mechanism"
XP_053980298.1	2	Reactome: R-HSA-6787450;Reactome: R-HSA-6782315	"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol"
XP_053986915.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053985979.1	7	Reactome: R-HSA-71064;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71403;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;KEGG: 00310+2.3.1.61	"Lysine catabolism";"Tryptophan metabolism";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation"
XP_053984803.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053980274.1	3	Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097	"Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway"
XP_053975438.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053993527.1	5	KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749	"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I"
XP_053979800.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981085.1	2	Reactome: R-HSA-5357905;Reactome: R-HSA-5357956	"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway"
XP_053985345.1	12	MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803	"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing"
XP_053985228.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053984105.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053986628.1	14	Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-203927;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8948700	"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation"
XP_053979844.1	4	Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17;KEGG: 00860+6.1.1.17	"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism"
XP_053974264.1	13	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053977611.1	3	Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54	"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism"
XP_053976026.1	5	Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614	"Pyrimidine catabolism";"Pyrimidine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage"
XP_053995020.1	2	KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10	"One carbon pool by folate";"Glycine, serine and threonine metabolism"
XP_053973603.1	16	Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8934593;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-426496	"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Oncogene Induced Senescence";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Regulation of RUNX1 Expression and Activity";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs"
XP_053973585.1	5	Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387	"Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling"
XP_053976636.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053972724.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053988409.1	3	Reactome: R-HSA-2559580;Reactome: R-HSA-8939243;Reactome: R-HSA-8943724	"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription"
XP_053974009.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053993405.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053991615.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053980105.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053976448.1	1	Reactome: R-HSA-5662702	"Melanin biosynthesis"
XP_053972536.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053985786.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214	"Formation of Incision Complex in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins"
XP_053994092.1	2	KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20	"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis"
XP_053981626.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053975947.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053981163.1	3	KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2	"Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism"
XP_053981940.1	1	Reactome: R-HSA-352230	"Amino acid transport across the plasma membrane"
XP_053975717.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053975236.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053987082.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053970455.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053988491.1	14	Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-69091;Reactome: R-HSA-5656121	"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Polymerase switching";"Translesion synthesis by POLI"
XP_053993935.1	4	KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943	"Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates"
XP_053990816.1	7	MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;MetaCyc: PWY-7255;Reactome: R-HSA-5578999	"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)"
XP_053978494.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053986854.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053983544.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053971999.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053984949.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053977418.1	2	Reactome: R-HSA-6814122;Reactome: R-HSA-418594	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events"
XP_053981041.1	1	Reactome: R-HSA-3000471	"Scavenging by Class B Receptors"
XP_053971044.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053992315.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053980825.1	13	Reactome: R-HSA-2243919;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-1474244;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171	"Crosslinking of collagen fibrils";"Integrin cell surface interactions";"Collagen chain trimerization";"NCAM1 interactions";"Signaling by PDGF";"Anchoring fibril formation";"ECM proteoglycans";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"Extracellular matrix organization";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Non-integrin membrane-ECM interactions"
XP_053983500.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053972866.1	3	Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840	"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle"
XP_053978159.1	13	Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-1799339	"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane"
XP_053992783.1	6	MetaCyc: PWY-7980;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2	"ATP biosynthesis";"Mitochondrial protein import";"Oxidative phosphorylation";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis"
XP_053992935.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053986600.1	13	Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-6804757;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852	"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy"
XP_053983326.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053973748.1	3	Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_053983212.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053989458.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053985244.1	2	Reactome: R-HSA-2142691;Reactome: R-HSA-2142700	"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)"
XP_053980719.1	1	Reactome: R-HSA-75105	"Fatty acyl-CoA biosynthesis"
XP_053995008.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053980949.1	8	MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105	"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation"
XP_053993315.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053979828.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_053976641.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053982500.1	7	Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00010+2.3.1.12;KEGG: 00620+2.3.1.12;Reactome: R-HSA-204174;KEGG: 00020+2.3.1.12	"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)"
XP_053988055.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053977023.1	6	KEGG: 00680+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11	"Methane metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism"
XP_053985200.1	3	Reactome: R-HSA-9645722;Reactome: R-HSA-140837;Reactome: R-HSA-111471	"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response"
XP_053985024.1	7	MetaCyc: PWY-7586;MetaCyc: PWY-7456;MetaCyc: PWY-882;KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00051+5.4.2.8	"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Fructose and mannose metabolism"
XP_053983210.1	4	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_053980758.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053979122.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-983231	"Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production"
XP_053982445.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053984666.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053972086.1	5	Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-983170	"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_053972035.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053992423.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053987287.1	8	MetaCyc: PWY-7817;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5668	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis I"
XP_053974068.1	56	Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949	"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin"
XP_053993687.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053990757.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053977178.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053987080.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053987191.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053976231.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-8866654	"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins"
XP_053978810.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-9033500	"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins"
XP_053980123.1	5	Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740	"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs"
XP_053979169.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053972625.1	27	Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-1169408;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-4551638;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-170822	"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"ISG15 antiviral mechanism";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein"
XP_053970554.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-8953750	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6"
XP_053985510.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053986781.1	3	Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9	"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis"
XP_053989183.1	19	Reactome: R-HSA-3214858;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-8876725;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"RMTs methylate histone arginines";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Protein methylation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_053992018.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053977369.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_053975631.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053983502.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053994052.1	11	Reactome: R-HSA-8939236;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-428890;Reactome: R-HSA-5685938;Reactome: R-HSA-8940973;Reactome: R-HSA-983231;Reactome: R-HSA-5663213	"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Myogenesis";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"HDR through Single Strand Annealing (SSA)";"RUNX2 regulates osteoblast differentiation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate WASPs and WAVEs"
XP_053981481.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053984130.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053980366.1	1	Reactome: R-HSA-3238698	"WNT ligand biogenesis and trafficking"
XP_053972248.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053975548.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_053980456.1	8	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053984675.1	1	Reactome: R-HSA-9033241	"Peroxisomal protein import"
XP_053993283.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053977032.1	7	Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_053987505.1	10	KEGG: 00410+2.6.1.19;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;Reactome: R-HSA-916853;KEGG: 00650+2.6.1.19;MetaCyc: PWY-6537;MetaCyc: PWY-5022;MetaCyc: PWY-4321	"beta-Alanine metabolism";"4-aminobutanoate degradation I";"Propanoate metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"Degradation of GABA";"Butanoate metabolism";"4-aminobutanoate degradation II";"4-aminobutanoate degradation V";"L-glutamate degradation IV"
XP_053984219.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053974950.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_053983388.1	3	Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214	"Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs"
XP_053983927.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053992387.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053988963.1	2	KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383	"Other glycan degradation";"Lysosomal oligosaccharide catabolism"
XP_053976809.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_053988766.1	2	Reactome: R-HSA-909733;Reactome: R-HSA-8983711	"Interferon alpha/beta signaling";"OAS antiviral response"
XP_053992283.1	33	Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-3108214;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-1169408	"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Mitotic Prometaphase";"ISG15 antiviral mechanism"
XP_053987427.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053980838.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053985914.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053986302.1	2	Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29	"Threonine catabolism";"Glycine, serine and threonine metabolism"
XP_053985744.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053975741.1	8	KEGG: 00030+5.3.1.6;KEGG: 00051+5.3.1.6;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6;Reactome: R-HSA-5659996	"Pentose phosphate pathway";"Fructose and mannose metabolism";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of R5P to RU5P"
XP_053973325.1	5	MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855	"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)"
XP_053980675.1	2	Reactome: R-HSA-8949664;Reactome: R-HSA-8949215	"Processing of SMDT1";"Mitochondrial calcium ion transport"
XP_053978056.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053984456.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053993387.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053972173.1	1	Reactome: R-HSA-5617833	"Cilium Assembly"
XP_053977622.1	11	Reactome: R-HSA-109704;Reactome: R-HSA-1632852;Reactome: R-HSA-1660499;MetaCyc: PWY-6352;Reactome: R-HSA-168138;KEGG: 04070+2.7.1.137;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-5668599;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517	"PI3K Cascade";"Macroautophagy";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"Toll Like Receptor 9 (TLR9) Cascade";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane"
XP_053991504.1	7	MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8	"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism"
XP_053988275.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053993432.1	1	Reactome: R-HSA-156842	"Eukaryotic Translation Elongation"
XP_053993279.1	8	Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897	"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes"
XP_053976538.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053984509.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053972446.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053970952.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053978776.1	1	Reactome: R-HSA-6799198	"Complex I biogenesis"
XP_053983163.1	20	Reactome: R-HSA-380972;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371571;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1257604;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-165159	"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"HSF1-dependent transactivation";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Thermogenesis";"PIP3 activates AKT signaling";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Human cytomegalovirus infection";"TP53 Regulates Metabolic Genes";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"mTOR signalling"
XP_053986300.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053970376.1	7	KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1	"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection"
XP_053977716.1	6	MetaCyc: PWY-3341;MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6922	"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis"
XP_053977237.1	1	Reactome: R-HSA-212300	"PRC2 methylates histones and DNA"
XP_053986197.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis"
XP_053972638.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053990353.1	1	Reactome: R-HSA-2559584	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"
XP_053988619.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053973901.1	8	Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68867	"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex"
XP_053983904.1	8	Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747	"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Degradation";"Regulation of PTEN localization"
XP_053986344.1	2	Reactome: R-HSA-5578775;Reactome: R-HSA-2672351	"Ion homeostasis";"Stimuli-sensing channels"
XP_053995011.1	9	Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_053987787.1	1	Reactome: R-HSA-1483191	"Synthesis of PC"
XP_053980132.1	5	Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-5620924	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport"
XP_053975896.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053976731.1	2	Reactome: R-HSA-6796648;Reactome: R-HSA-6783310	"TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway"
XP_053987404.1	4	Reactome: R-HSA-8875555;Reactome: R-HSA-8875656;Reactome: R-HSA-912631;Reactome: R-HSA-186763	"MET activates RAP1 and RAC1";"MET receptor recycling";"Regulation of signaling by CBL";"Downstream signal transduction"
XP_053982626.1	6	Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-73856	"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination"
XP_053970665.1	24	Reactome: R-HSA-202424;Reactome: R-HSA-5218920;KEGG: 05163+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-9634635;Reactome: R-HSA-2871837;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-5625740;Reactome: R-HSA-5607764;Reactome: R-HSA-165158;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;KEGG: 04150+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-6804757	"Downstream TCR signaling";"VEGFR2 mediated vascular permeability";"Human cytomegalovirus infection";"CD28 dependent PI3K/Akt signaling";"Human papillomavirus infection";"PIP3 activates AKT signaling";"Estrogen-stimulated signaling through PRKCZ";"FCERI mediated NF-kB activation";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"RHO GTPases activate PKNs";"CLEC7A (Dectin-1) signaling";"Activation of AKT2";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RSK activation";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"mTOR signaling pathway";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Regulation of TP53 Degradation"
XP_053977401.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053988596.1	3	Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053971603.1	2	Reactome: R-HSA-9033241;Reactome: R-HSA-389661	"Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation"
XP_053971585.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053989953.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053994463.1	3	KEGG: 00051+1.1.1.271;KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639	"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis"
XP_053973413.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053992279.1	4	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695;Reactome: R-HSA-5694530	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Neutrophil degranulation";"Cargo concentration in the ER"
XP_053992432.1	10	KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13	"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism"
XP_053971536.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053982904.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053983036.1	3	Reactome: R-HSA-5657562;Reactome: R-HSA-70350;KEGG: 00051+2.7.1.3	"Essential fructosuria";"Fructose catabolism";"Fructose and mannose metabolism"
XP_053986526.1	5	MetaCyc: PWY-7082;MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8	"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation"
XP_053971724.1	2	Reactome: R-HSA-72702;Reactome: R-HSA-72706	"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053981721.1	6	Reactome: R-HSA-76005;Reactome: R-HSA-114516;Reactome: R-HSA-5099900;Reactome: R-HSA-418597;Reactome: R-HSA-416993;KEGG: 04070+2.7.11.13	"Response to elevated platelet cytosolic Ca2+";"Disinhibition of SNARE formation";"WNT5A-dependent internalization of FZD4";"G alpha (z) signalling events";"Trafficking of GluR2-containing AMPA receptors";"Phosphatidylinositol signaling system"
XP_053972189.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_053984798.1	4	Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18;MetaCyc: PWY-5874;Reactome: R-HSA-189483	"Iron uptake and transport";"Porphyrin and chlorophyll metabolism";"Heme degradation I";"Heme degradation"
XP_053979354.1	1	Reactome: R-HSA-400253	"Circadian Clock"
XP_053987934.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053991315.1	18	Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-113418;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-167200	"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of the Early Elongation Complex";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat"
XP_053977499.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053994951.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_053973207.1	3	Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648	"Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK"
XP_053979464.1	56	Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-8852276;Reactome: R-HSA-4608870;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-5687128;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664	"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Asymmetric localization of PCP proteins";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"MAPK6/MAPK4 signaling";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation"
XP_053981326.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-3214847	"Ub-specific processing proteases";"HATs acetylate histones"
XP_053982434.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053990797.1	19	Reactome: R-HSA-5627123;Reactome: R-HSA-194840;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-5663220;Reactome: R-HSA-983231;Reactome: R-HSA-8950505;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-182971;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-5663213;Reactome: R-HSA-5626467	"RHO GTPases activate PAKs";"Rho GTPase cycle";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases Activate Formins";"Factors involved in megakaryocyte development and platelet production";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"EGFR downregulation";"Myogenesis";"CD28 dependent Vav1 pathway";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate IQGAPs"
XP_053980591.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC"
XP_053971918.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits"
XP_053994134.1	1	Reactome: R-HSA-8856828	"Clathrin-mediated endocytosis"
XP_053974578.1	1	KEGG: 00531+3.2.1.35	"Glycosaminoglycan degradation"
XP_053971338.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053975012.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053985645.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053974594.1	1	Reactome: R-HSA-83936	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane"
XP_053994797.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053976868.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053989114.1	3	Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533	"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis"
XP_053975507.1	2	Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15	"Detoxification of Reactive Oxygen Species";"Glutathione metabolism"
XP_053985488.1	7	KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1	"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway"
XP_053976746.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053991986.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053983434.1	2	Reactome: R-HSA-4090294;Reactome: R-HSA-383280	"SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway"
XP_053970771.1	3	Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700	"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)"
XP_053986245.1	18	MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482839	"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Ether lipid metabolism";"Acyl chain remodelling of PI";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE"
XP_053981544.1	42	Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-3214841;Reactome: R-HSA-5693565;Reactome: R-HSA-427413;Reactome: R-HSA-201722;Reactome: R-HSA-2559582;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-110328;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-912446;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-9610379;Reactome: R-HSA-2299718;Reactome: R-HSA-5334118;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-2559586	"PRC2 methylates histones and DNA";"Amyloid fiber formation";"PKMTs methylate histone lysines";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NoRC negatively regulates rRNA expression";"Formation of the beta-catenin:TCF transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"HCMV Early Events";"RMTs methylate histone arginines";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Meiotic recombination";"Estrogen-dependent gene expression";"Meiotic synapsis";"HDACs deacetylate histones";"HCMV Late Events";"Condensation of Prophase Chromosomes";"DNA methylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence"
XP_053991783.1	2	Reactome: R-HSA-6784531;Reactome: R-HSA-6785470	"tRNA processing in the nucleus";"tRNA processing in the mitochondrion"
XP_053991935.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053975010.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053981017.1	16	Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-9018519;Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568	"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Estrogen-dependent gene expression";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053993900.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination"
XP_053981688.1	3	Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4	"Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis"
XP_053973224.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053985728.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053993099.1	6	Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-69473	"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint"
XP_053983535.1	2	KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7	"Pyruvate metabolism";"Aminobenzoate degradation"
XP_053974764.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053981876.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053983586.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053989474.1	12	MetaCyc: PWY-5857;MetaCyc: PWY-5871;Reactome: R-HSA-2142789;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-7233;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-5870;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5872;MetaCyc: PWY-7230	"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)"
XP_053982221.1	3	Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148	"VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053972224.1	6	Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;KEGG: 00190+7.1.2.2	"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Oxidative phosphorylation"
XP_053976088.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053978821.1	7	Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052	"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion"
XP_053992099.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053986635.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053978199.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation"
XP_053992900.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription"
XP_053980761.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053985286.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053976129.1	2	Reactome: R-HSA-383280;Reactome: R-HSA-210745	"Nuclear Receptor transcription pathway";"Regulation of gene expression in beta cells"
XP_053972517.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053988361.1	12	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation"
XP_053985235.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053992714.1	10	Reactome: R-HSA-156827;Reactome: R-HSA-72731;Reactome: R-HSA-381042;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-72649;Reactome: R-HSA-382556;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"Translation initiation complex formation";"ABC-family proteins mediated transport";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053978454.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053986923.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053980396.1	9	KEGG: 00010+1.2.1.12;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70171;Reactome: R-HSA-70263	"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Gluconeogenesis"
XP_053991727.1	1	Reactome: R-HSA-1483101	"Synthesis of PS"
XP_053986610.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053980709.1	5	Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693565	"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053971524.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053983202.1	22	MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7035;MetaCyc: PWY-8041;MetaCyc: PWY-7728;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7592;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7049;Reactome: R-HSA-75876;MetaCyc: PWY-7602;KEGG: 00062+4.2.1.134	"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation"
XP_053981153.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-6799198	"Respiratory electron transport";"Complex I biogenesis"
XP_053976531.1	5	Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880	"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Ub-specific processing proteases"
XP_053993305.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053994806.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053985210.1	4	Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737	"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis"
XP_053980251.1	8	Reactome: R-HSA-1855183;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-6664	"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis"
XP_053989661.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053971217.1	1	Reactome: R-HSA-3371453	"Regulation of HSF1-mediated heat shock response"
XP_053979664.1	4	KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024	"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"DARPP-32 events"
XP_053971736.1	1	Reactome: R-HSA-3214842	"HDMs demethylate histones"
XP_053988993.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053985688.1	16	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053982202.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053985017.1	2	Reactome: R-HSA-975577;Reactome: R-HSA-2022854	"N-Glycan antennae elongation";"Keratan sulfate biosynthesis"
XP_053972908.1	5	KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-6317	"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)"
XP_053990806.1	3	Reactome: R-HSA-6791226;Reactome: R-HSA-8951664;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation";"rRNA modification in the nucleus and cytosol"
XP_053975086.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053987587.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053976738.1	1	Reactome: R-HSA-5666185	"RHO GTPases Activate Rhotekin and Rhophilins"
XP_053992305.1	29	Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-3371511;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-3108214;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-6804756;Reactome: R-HSA-110312;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-5656169;Reactome: R-HSA-69473	"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HSF1 activation";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"SUMOylation of DNA damage response and repair proteins";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Regulation of TP53 Activity through Phosphorylation";"Translesion synthesis by REV1";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"Termination of translesion DNA synthesis";"G2/M DNA damage checkpoint"
XP_053982024.1	2	KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981	"Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis"
XP_053976982.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053978576.1	1	Reactome: R-HSA-5693607	"Processing of DNA double-strand break ends"
XP_053982200.1	1	Reactome: R-HSA-2028269	"Signaling by Hippo"
XP_053981645.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053986149.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053971507.1	7	KEGG: 00030+3.1.1.31;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514;MetaCyc: PWY-8004;Reactome: R-HSA-71336;MetaCyc: PWY-6855;MetaCyc: PWY-6906	"Pentose phosphate pathway";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Entner-Doudoroff pathway I";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Chitin derivatives degradation"
XP_053973384.1	1	Reactome: R-HSA-418594	"G alpha (i) signalling events"
XP_053992921.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053983007.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053982244.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053986167.1	1	Reactome: R-HSA-1483148	"Synthesis of PG"
XP_053991166.1	29	Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-427413;Reactome: R-HSA-73863	"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination"
XP_053978844.1	2	Reactome: R-HSA-416476;Reactome: R-HSA-389397	"G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors"
XP_053991623.1	1	Reactome: R-HSA-3299685	"Detoxification of Reactive Oxygen Species"
XP_053975541.1	11	MetaCyc: PWY-7791;KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00250+6.3.5.5;KEGG: 00250+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-5154;MetaCyc: PWY-7400;KEGG: 00240+2.1.3.2;KEGG: 00240+6.3.5.5	"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Pyrimidine metabolism"
XP_053971425.1	14	Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167287	"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery"
XP_053982381.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053975866.1	2	MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11	"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis"
XP_053986612.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053995059.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053989409.1	15	MetaCyc: PWY-6886;MetaCyc: PWY-5484;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-2221;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7218	"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Purine metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)"
XP_053994570.1	7	MetaCyc: PWY-7185;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-6545;KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7198	"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Thiamine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_053988566.1	12	Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813	"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids"
XP_053980831.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781	"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression"
XP_053977206.1	1	KEGG: 00970+6.3.5.7	"Aminoacyl-tRNA biosynthesis"
XP_053985326.1	1	Reactome: R-HSA-525793	"Myogenesis"
XP_053981855.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053986435.1	16	Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957	"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053975918.1	12	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-381038;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"XBP1(S) activates chaperone genes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane"
XP_053991487.1	24	Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434;Reactome: R-HSA-9646399;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-437239;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-8955332;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833	"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic";"Aggrephagy";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recycling pathway of L1";"Gap junction assembly";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Carboxyterminal post-translational modifications of tubulin";"Kinesins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Activation of AMPK downstream of NMDARs";"Cilium Assembly"
XP_053987705.1	3	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053972285.1	1	Reactome: R-HSA-202733	"Cell surface interactions at the vascular wall"
XP_053972947.1	1	Reactome: R-HSA-69231	"Cyclin D associated events in G1"
XP_053993242.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053984768.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053993889.1	8	KEGG: 00051+5.3.1.6;KEGG: 00030+5.3.1.6;Reactome: R-HSA-71336;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6	"Fructose and mannose metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms"
XP_053972717.1	2	Reactome: R-HSA-2672351;Reactome: R-HSA-5578775	"Stimuli-sensing channels";"Ion homeostasis"
XP_053972236.1	1	Reactome: R-HSA-5389840	"Mitochondrial translation elongation"
XP_053987642.1	2	Reactome: R-HSA-5693568;Reactome: R-HSA-6783310	"Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway"
XP_053971896.1	5	KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317	"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053982983.1	2	Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198	"Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis"
XP_053975536.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053977359.1	3	KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783	"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis"
XP_053982735.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053975603.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053982786.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_053976203.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053972969.1	2	Reactome: R-HSA-5578999;Reactome: R-HSA-174403	"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling"
XP_053973922.1	4	Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970	"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1"
XP_053984846.1	11	KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695;MetaCyc: PWY-7185;MetaCyc: PWY-6596;KEGG: 00230+3.1.3.5;MetaCyc: PWY-6607;KEGG: 00240+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7821;MetaCyc: PWY-6606;MetaCyc: PWY-6608	"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"UTP and CTP dephosphorylation I";"Adenosine nucleotides degradation I";"Purine metabolism";"Guanosine nucleotides degradation I";"Pyrimidine metabolism";"Pyridine nucleotide cycling (plants)";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III"
XP_053985721.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053992630.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053979159.1	1	Reactome: R-HSA-5620912	"Anchoring of the basal body to the plasma membrane"
XP_053980656.1	3	Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476	"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053974564.1	7	KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;Reactome: R-HSA-210500	"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Glutamate Neurotransmitter Release Cycle"
XP_053980813.1	1	Reactome: R-HSA-4551638	"SUMOylation of chromatin organization proteins"
XP_053983786.1	1	Reactome: R-HSA-5624958	"ARL13B-mediated ciliary trafficking of INPP5E"
XP_053992020.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053977422.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053978120.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053976307.1	5	Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23	"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism"
XP_053982228.1	11	Reactome: R-HSA-9018519;Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082	"Estrogen-dependent gene expression";"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression"
XP_053988179.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053990339.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053977780.1	3	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing"
XP_053982979.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_053989775.1	17	Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1	"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Thermogenesis";"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection"
XP_053972438.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053980957.1	7	Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912	"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane"
XP_053971741.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053980574.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053993069.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053978122.1	2	Reactome: R-HSA-390471;Reactome: R-HSA-1660662	"Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism"
XP_053974019.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053979276.1	3	MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3	"Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism"
XP_053993873.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-9010553	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs"
XP_053991583.1	9	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053971911.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053992240.1	6	Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827	"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053980598.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053989358.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_053984791.1	5	Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-430039	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease"
XP_053976192.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053972646.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053993632.1	30	Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-73776;Reactome: R-HSA-2564830;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053974794.1	1	Reactome: R-HSA-2393930	"Phosphate bond hydrolysis by NUDT proteins"
XP_053989468.1	3	Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434	"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053981700.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053983426.1	4	Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.16	"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism"
XP_053975707.1	2	MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222	"Psilocybin biosynthesis";"Indole alkaloid biosynthesis"
XP_053994958.1	3	Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6	"Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism"
XP_053990958.1	9	Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776	"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape"
XP_053978755.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053993240.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053987723.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053990597.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053979810.1	1	Reactome: R-HSA-5689603	"UCH proteinases"
XP_053988256.1	1	Reactome: R-HSA-6787450	"tRNA modification in the mitochondrion"
XP_053993022.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"Peptide chain elongation";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053972856.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053971548.1	2	Reactome: R-HSA-1236394;Reactome: R-HSA-977443	"Signaling by ERBB4";"GABA receptor activation"
XP_053978394.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053988183.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689	"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits"
XP_053988391.1	5	Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482	"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation"
XP_053984574.1	2	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878	"Intra-Golgi traffic";"COPI-mediated anterograde transport"
XP_053993204.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053970465.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053978147.1	7	MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039	"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule"
XP_053973920.1	2	Reactome: R-HSA-381038;Reactome: R-HSA-1799339	"XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane"
XP_053994126.1	13	Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-5607763	"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation"
XP_053992632.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053986864.1	33	Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-73776;Reactome: R-HSA-69656;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-69273;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-69231;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-69202;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-8939236;Reactome: R-HSA-75955;Reactome: R-HSA-6796648	"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin D associated events in G1";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin E associated events during G1/S transition";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053994663.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053970355.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053981349.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053993114.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053994302.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053989902.1	5	MetaCyc: PWY-7863;MetaCyc: PWY-6168;KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523	"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)";"Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)"
XP_053992461.1	1	Reactome: R-HSA-5676934	"Protein repair"
XP_053981367.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163	"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway"
XP_053975063.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053974706.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053975879.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053975360.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053974399.1	7	Reactome: R-HSA-204174;Reactome: R-HSA-5362517;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism"
XP_053986837.1	7	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection"
XP_053984205.1	1	Reactome: R-HSA-430039	"mRNA decay by 5' to 3' exoribonuclease"
XP_053993575.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053988579.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053980414.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053985128.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053975450.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_053980205.1	9	MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12	"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis";"Glycolysis / Gluconeogenesis"
XP_053978014.1	14	MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;Reactome: R-HSA-975634;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803	"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing"
XP_053985372.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053984414.1	16	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation"
XP_053970399.1	1	Reactome: R-HSA-8849932	"Synaptic adhesion-like molecules"
XP_053970903.1	3	Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942	"Glutathione synthesis and recycling";"Glutathione metabolism";"5-oxo-L-proline metabolism"
XP_053993296.1	5	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-390450	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Folding of actin by CCT/TriC"
XP_053971289.1	1	Reactome: R-HSA-198933	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"
XP_053987696.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053971842.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053979559.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053991368.1	5	Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185	"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"UTP and CTP dephosphorylation I"
XP_053977074.1	10	MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453	"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis"
XP_053985370.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053979195.1	12	Reactome: R-HSA-2660826;Reactome: R-HSA-1251985;Reactome: R-HSA-75893;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-5362798;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-982772;Reactome: R-HSA-1442490	"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Nuclear signaling by ERBB4";"TNF signaling";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Release of Hh-Np from the secreting cell";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Growth hormone receptor signaling";"Collagen degradation"
XP_053990344.1	3	Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097	"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway"
XP_053986353.1	22	Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-195253;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-196299;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-141444;Reactome: R-HSA-5358752	"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"Degradation of beta-catenin by the destruction complex";"RAF activation";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Beta-catenin phosphorylation cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated"
XP_053979406.1	6	KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107	"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism"
XP_053971840.1	2	Reactome: R-HSA-2132295;Reactome: R-HSA-877300	"MHC class II antigen presentation";"Interferon gamma signaling"
XP_053991419.1	3	MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23	"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism"
XP_053985847.1	3	Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984198.1	5	Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949	"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin"
XP_053990300.1	5	Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053983497.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_053979518.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-1268020	"Respiratory electron transport";"Mitochondrial protein import"
XP_053994526.1	12	Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246	"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript"
XP_053994003.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053976146.1	2	Reactome: R-HSA-2243919;Reactome: R-HSA-1566948	"Crosslinking of collagen fibrils";"Elastic fibre formation"
XP_053972692.1	2	Reactome: R-HSA-8939243;Reactome: R-HSA-3214858	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines"
XP_053994300.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053995140.1	3	KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347	"Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis"
XP_053991183.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053987064.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053977061.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053980174.1	9	Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-2173796;Reactome: R-HSA-167290;Reactome: R-HSA-167152	"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat"
XP_053982497.1	1	Reactome: R-HSA-216083	"Integrin cell surface interactions"
XP_053986257.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053980515.1	14	MetaCyc: PWY-7589;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587	"Palmitoleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)"
XP_053995104.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053970537.1	4	Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497	"Estrogen-dependent gene expression";"ESR-mediated signaling";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)"
XP_053994197.1	2	Reactome: R-HSA-1169408;Reactome: R-HSA-168276	"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways"
XP_053979711.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_053989714.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_053970282.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053979004.1	3	KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355	"Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction"
XP_053977960.1	1	Reactome: R-HSA-442660	"Na+/Cl- dependent neurotransmitter transporters"
XP_053980327.1	10	Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6527;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-6317	"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)"
XP_053985102.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053983472.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053989430.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053987187.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286	"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation"
XP_053984342.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053974925.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053988332.1	3	KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369	"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis"
XP_053994245.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994987.1	4	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes"
XP_053971392.1	3	MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814	"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes"
XP_053983966.1	2	Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53	"DARPP-32 events";"Purine metabolism"
XP_053983110.1	3	MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887	"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation"
XP_053972053.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053976577.1	6	Reactome: R-HSA-173599;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00053+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7346	"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Ascorbate and aldarate metabolism";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)"
XP_053972789.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053988912.1	10	Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607	"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends"
XP_053974867.1	1	MetaCyc: PWY-7799	"Arg/N-end rule pathway (eukaryotic)"
XP_053979247.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053979985.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053971124.1	52	Reactome: R-HSA-167243;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-113418;Reactome: R-HSA-73780;Reactome: R-HSA-73762;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167162;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-72203;Reactome: R-HSA-6782135;Reactome: R-HSA-203927;Reactome: R-HSA-167200;Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-167238;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-5250924;Reactome: R-HSA-5578749;Reactome: R-HSA-5601884	"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"Formation of the Early Elongation Complex";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Transcription Initiation";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processing of Capped Intron-Containing Pre-mRNA";"Dual incision in TC-NER";"MicroRNA (miRNA) biogenesis";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"B-WICH complex positively regulates rRNA expression";"Transcriptional regulation by small RNAs";"PIWI-interacting RNA (piRNA) biogenesis"
XP_053978218.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes"
XP_053994172.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053981121.1	29	KEGG: 05163+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693548;Reactome: R-HSA-349425;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693579;KEGG: 04926+2.7.11.1;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-6796648;Reactome: R-HSA-6804757;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6804760;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-69541;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-6803204;Reactome: R-HSA-5693571;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607	"Human cytomegalovirus infection";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Sensing of DNA Double Strand Breaks";"Autodegradation of the E3 ubiquitin ligase COP1";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Thermogenesis";"Homologous DNA Pairing and Strand Exchange";"Relaxin signaling pathway";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Degradation";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Activity through Methylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Stabilization of p53";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Nonhomologous End-Joining (NHEJ)";"PI3K-Akt signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends"
XP_053990987.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053973053.1	11	Reactome: R-HSA-5687128;Reactome: R-HSA-8943724;Reactome: R-HSA-8862803;Reactome: R-HSA-2871796;Reactome: R-HSA-6796648;Reactome: R-HSA-1912408;Reactome: R-HSA-2559582;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-450341	"MAPK6/MAPK4 signaling";"Regulation of PTEN gene transcription";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"FCERI mediated MAPK activation";"TP53 Regulates Transcription of DNA Repair Genes";"Pre-NOTCH Transcription and Translation";"Senescence-Associated Secretory Phenotype (SASP)";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the AP-1 family of transcription factors"
XP_053977278.1	1	Reactome: R-HSA-71288	"Creatine metabolism"
XP_053982966.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053993691.1	1	Reactome: R-HSA-176974	"Unwinding of DNA"
XP_053973350.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053986134.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053987291.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053984732.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_053993076.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053982470.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053970301.1	11	Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-389948;Reactome: R-HSA-391160;Reactome: R-HSA-512988;Reactome: R-HSA-877312;Reactome: R-HSA-210990;Reactome: R-HSA-432142;Reactome: R-HSA-388841;Reactome: R-HSA-909733	"GPVI-mediated activation cascade";"Interleukin-37 signaling";"Regulation of IFNA signaling";"PD-1 signaling";"Signal regulatory protein family interactions";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Regulation of IFNG signaling";"PECAM1 interactions";"Platelet sensitization by LDL";"Costimulation by the CD28 family";"Interferon alpha/beta signaling"
XP_053975995.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053988910.1	15	Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-174154	"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin"
XP_053982859.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053988166.1	9	Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001	"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"EPHB-mediated forward signaling";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade"
XP_053991841.1	1	Reactome: R-HSA-425381	"Bicarbonate transporters"
XP_053983667.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053992668.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_053994170.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053980043.1	14	KEGG: 00720+1.3.5.1;MetaCyc: PWY-7254;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-3781;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;KEGG: 00650+1.3.5.1	"Carbon fixation pathways in prokaryotes";"TCA cycle VII (acetate-producers)";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Butanoate metabolism"
XP_053984730.1	6	Reactome: R-HSA-2046105;Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045;Reactome: R-HSA-9603798	"Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Class I peroxisomal membrane protein import"
XP_053983649.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053974280.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053994412.1	1	Reactome: R-HSA-2514853	"Condensation of Prometaphase Chromosomes"
XP_053972773.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053983859.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053977962.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_053993668.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-9608290;Reactome: R-HSA-110328	"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Defective MUTYH substrate processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_053987268.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_053992756.1	2	Reactome: R-HSA-5619061;Reactome: R-HSA-425397	"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules"
XP_053984340.1	2	Reactome: R-HSA-429958;Reactome: R-HSA-390471	"mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis"
XP_053990878.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053984043.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053992953.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8951664;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5632684;Reactome: R-HSA-69601	"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Neddylation";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A"
XP_053988330.1	3	MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167	"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol"
XP_053990170.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053978682.1	10	MetaCyc: PWY-6365;Reactome: R-HSA-983231;MetaCyc: PWY-6362;Reactome: R-HSA-1855167;MetaCyc: PWY-6366;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-4661;MetaCyc: PWY-6554;Reactome: R-HSA-1855204;KEGG: 04070+2.7.1.159	"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system"
XP_053988033.1	6	Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642	"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle"
XP_053989615.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053972462.1	3	Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841	"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines"
XP_053971390.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_053974301.1	1	Reactome: R-HSA-6811436	"COPI-independent Golgi-to-ER retrograde traffic"
XP_053978508.1	1	Reactome: R-HSA-5628897	"TP53 Regulates Metabolic Genes"
XP_053979220.1	3	Reactome: R-HSA-3000171;Reactome: R-HSA-3000157;Reactome: R-HSA-8874081	"Non-integrin membrane-ECM interactions";"Laminin interactions";"MET activates PTK2 signaling"
XP_053980287.1	16	Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695	"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Neddylation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events"
XP_053980945.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053987375.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053984191.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053984080.1	9	Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-9656255	"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding"
XP_053970737.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053974347.1	2	Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28	"Digestion of dietary carbohydrate";"Starch and sucrose metabolism"
XP_053990610.1	5	Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-983170	"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC"
XP_053975093.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053974459.1	3	Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2	"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism"
XP_053976560.1	1	Reactome: R-HSA-6811440	"Retrograde transport at the Trans-Golgi-Network"
XP_053981808.1	3	KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221	"Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis"
XP_053993319.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-8866427;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-437239	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Recycling pathway of L1"
XP_053978722.1	13	Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits"
XP_053988986.1	15	MetaCyc: PWY-5723;MetaCyc: PWY-7383;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-1042;MetaCyc: PWY-7003;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-8004;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-2221;Reactome: R-HSA-70171	"Rubisco shunt";"Anaerobic energy metabolism (invertebrates, cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Pyruvate metabolism";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Entner-Doudoroff pathway I";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis"
XP_053988935.1	2	Reactome: R-HSA-416482;Reactome: R-HSA-456926	"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)"
XP_053989323.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053994923.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053984862.1	1	Reactome: R-HSA-426486	"Small interfering RNA (siRNA) biogenesis"
XP_053979718.1	9	Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501	"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_053989889.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-141444	"Aggrephagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal"
XP_053970459.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053973660.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053980829.1	3	Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053974243.1	3	KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1	"Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism"
XP_053992319.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053987551.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-375276	"G alpha (i) signalling events";"Peptide ligand-binding receptors"
XP_053974216.1	1	Reactome: R-HSA-1474228	"Degradation of the extracellular matrix"
XP_053974322.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823	"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex"
XP_053984945.1	3	Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066	"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter"
XP_053986806.1	2	Reactome: R-HSA-4641262;Reactome: R-HSA-196299	"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade"
XP_053984287.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053982253.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053986570.1	10	MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6361;MetaCyc: PWY-6369;KEGG: 00562+2.7.1.158;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;Reactome: R-HSA-1855167	"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol diphosphates biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of pyrophosphates in the cytosol"
XP_053989022.1	4	Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9	"Metabolism of folate and pterines";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis"
XP_053985121.1	1	KEGG: 00230+4.6.1.2	"Purine metabolism"
XP_053984379.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_053975124.1	1	Reactome: R-HSA-9633012	"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053979759.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053994612.1	7	KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16	"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism"
XP_053973662.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053978599.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053984168.1	2	Reactome: R-HSA-2408522;Reactome: R-HSA-379716	"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation"
XP_053977365.1	3	MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807	"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis"
XP_053983357.1	1	Reactome: R-HSA-5649702	"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"
XP_053992358.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053994486.1	14	MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-5972;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035	"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis"
XP_053979201.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053980082.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053988423.1	4	Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400	"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Dual Incision in GG-NER"
XP_053983467.1	4	MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581	"[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis"
XP_053974633.1	19	Reactome: R-HSA-3000497;Reactome: R-HSA-381426;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-3000471;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-8964041;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-5686938	"Scavenging by Class H Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"VLDL clearance";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Chylomicron clearance";"Scavenging by Class B Receptors";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"VLDL assembly";"Chylomicron assembly";"Platelet sensitization by LDL";"LDL clearance";"LDL remodeling";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand"
XP_053984082.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053987078.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053979437.1	5	MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210	"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine"
XP_053977091.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053993775.1	1	Reactome: R-HSA-425561	"Sodium/Calcium exchangers"
XP_053990435.1	2	Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation"
XP_053989047.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053983186.1	2	MetaCyc: PWY-7799;MetaCyc: PWY-7802	"Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)"
XP_053977888.1	9	Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952	"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions"
XP_053987719.1	2	Reactome: R-HSA-5658442;Reactome: R-HSA-6802953	"Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants"
XP_053988018.1	6	Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053983670.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053994167.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053978643.1	2	Reactome: R-HSA-611105;Reactome: R-HSA-71403	"Respiratory electron transport";"Citric acid cycle (TCA cycle)"
XP_053979380.1	2	KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7	"Aminobenzoate degradation";"Pyruvate metabolism"
XP_053993358.1	1	Reactome: R-HSA-6811434	"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053994871.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053979907.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053981657.1	17	KEGG: 04714+2.7.11.1;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9022692;Reactome: R-HSA-174178;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4615885;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-141444;Reactome: R-HSA-68877;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2467813	"Thermogenesis";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Regulation of MECP2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Human papillomavirus infection";"SUMOylation of DNA replication proteins";"Human cytomegalovirus infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Relaxin signaling pathway";"Separation of Sister Chromatids"
XP_053977009.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053980614.1	5	Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2	"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism"
XP_053971362.1	1	KEGG: 00970+6.1.1.9	"Aminoacyl-tRNA biosynthesis"
XP_053970897.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-171319	"HATs acetylate histones";"Telomere Extension By Telomerase"
XP_053994084.1	13	Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827	"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression"
XP_053991848.1	7	Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201	"Mitochondrial protein import";"ATP biosynthesis";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis"
XP_053981370.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72163	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway"
XP_053981869.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053987105.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-4086398	"cGMP effects";"Ca2+ pathway"
XP_053988504.1	7	Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69205	"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"G1/S-Specific Transcription"
XP_053986339.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053974308.1	8	Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-113501	"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Inhibition of replication initiation of damaged DNA by RB1/E2F1"
XP_053993661.1	7	Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73780	"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation"
XP_053974611.1	2	KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation"
XP_053995065.1	10	MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051	"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I"
XP_053975840.1	8	KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;Reactome: R-HSA-9639288;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-917977	"Photosynthesis";"Insulin receptor recycling";"Ion channel transport";"Oxidative phosphorylation";"Amino acids regulate mTORC1";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling"
XP_053971329.1	7	Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813	"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Separation of Sister Chromatids"
XP_053973490.1	13	KEGG: 00531+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2160916	"Glycosaminoglycan degradation";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Keratan sulfate degradation";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Hyaluronan uptake and degradation"
XP_053990871.1	3	KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16	"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway"
XP_053989305.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053981372.1	4	Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856	"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination"
XP_053974005.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053983697.1	1	Reactome: R-HSA-72203	"Processing of Capped Intron-Containing Pre-mRNA"
XP_053980981.1	2	Reactome: R-HSA-163210;Reactome: R-HSA-8949613	"Formation of ATP by chemiosmotic coupling";"Cristae formation"
XP_053975842.1	14	Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-2565942;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-380270;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025	"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Regulation of PLK1 Activity at G2/M Transition";"Mitotic Prometaphase";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Recruitment of mitotic centrosome proteins and complexes";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation"
XP_053986663.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053994864.1	2	Reactome: R-HSA-8856825;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis"
XP_053987803.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053981820.1	7	Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes"
XP_053976138.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053984109.1	1	Reactome: R-HSA-611105	"Respiratory electron transport"
XP_053993698.1	2	Reactome: R-HSA-72706;Reactome: R-HSA-72702	"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition"
XP_053977271.1	20	MetaCyc: PWY-7288;MetaCyc: PWY-7291;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7337;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7854;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-6920;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7606	"Fatty acid beta-oxidation VII (yeast peroxisome)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoate metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)"
XP_053993674.1	5	Reactome: R-HSA-110330;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287;Reactome: R-HSA-110357;Reactome: R-HSA-110331	"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine"
XP_053987274.1	4	Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;KEGG: 00983+2.7.1.48	"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Drug metabolism - other enzymes"
XP_053981089.1	2	Reactome: R-HSA-5357956;Reactome: R-HSA-5357905	"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling"
XP_053990864.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053992409.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-430039	"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease"
XP_053974984.1	3	Reactome: R-HSA-913709;Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117	"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis"
XP_053984981.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053972492.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053971063.1	14	MetaCyc: PWY-6433;MetaCyc: PWY-7602;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7035;MetaCyc: PWY-8041	"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Fatty acid elongation";"(9Z)-tricosene biosynthesis";"Ultra-long-chain fatty acid biosynthesis"
XP_053986958.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053988214.1	8	KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1	"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection"
XP_053977419.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053977065.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053983057.1	4	Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037	"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions"
XP_053978158.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053974323.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;KEGG: 00513+2.4.1.257+2.4.1.132	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Various types of N-glycan biosynthesis"
XP_053979715.1	1	Reactome: R-HSA-418886	"Netrin mediated repulsion signals"
XP_053986490.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053990236.1	2	Reactome: R-HSA-110320;Reactome: R-HSA-5689880	"Translesion Synthesis by POLH";"Ub-specific processing proteases"
XP_053990717.1	10	MetaCyc: PWY-6891;MetaCyc: PWY-6901;KEGG: 00710+2.2.1.1;KEGG: 00030+2.2.1.1;MetaCyc: PWY-6892;MetaCyc: PWY-5723;MetaCyc: PWY-1861;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;KEGG: 00730+2.2.1.7	"Thiazole biosynthesis II (aerobic bacteria)";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiamine metabolism"
XP_053982250.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053978479.1	6	KEGG: 00261+4.3.3.7;MetaCyc: PWY-8088;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2941;MetaCyc: PWY-2942;MetaCyc: PWY-5097	"Monobactam biosynthesis";"Dipicolinate biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"L-lysine biosynthesis VI"
XP_053970514.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-8876198	"RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs"
XP_053971557.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053989737.1	4	Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828	"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis"
XP_053975092.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053984511.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053979829.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053977256.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053978723.1	2	Reactome: R-HSA-804914;Reactome: R-HSA-9029569	"Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"
XP_053978640.1	13	KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;Reactome: R-HSA-4341670;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2022857;Reactome: R-HSA-2206308;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;KEGG: 00511+3.2.1.23;Reactome: R-HSA-1660662	"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Defective NEU1 causes sialidosis";"Sphingolipid metabolism";"HS-GAG degradation";"Galactose metabolism";"Keratan sulfate degradation";"MPS IV - Morquio syndrome B";"Neutrophil degranulation";"Sialic acid metabolism";"Other glycan degradation";"Glycosphingolipid metabolism"
XP_053989194.1	3	KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16	"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer"
XP_053972339.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053983673.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053974227.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-1989781	"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression"
XP_053976996.1	4	Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265	"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes"
XP_053984382.1	3	Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300	"SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors"
XP_053976793.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_053973919.1	2	Reactome: R-HSA-1799339;Reactome: R-HSA-381038	"SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes"
XP_053978604.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053987394.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053989459.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053995009.1	2	Reactome: R-HSA-6804115;Reactome: R-HSA-429947	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA"
XP_053978037.1	8	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053975090.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053993355.1	2	Reactome: R-HSA-204174;Reactome: R-HSA-5362517	"Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid"
XP_053975181.1	3	Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events"
XP_053977885.1	9	Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802948;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695	"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling by high-kinase activity BRAF mutants";"MAP2K and MAPK activation";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation"
XP_053989506.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053980201.1	16	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex"
XP_053988015.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053974415.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-4570464;Reactome: R-HSA-9610379;Reactome: R-HSA-72203	"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins";"HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA"
XP_053982689.1	2	Reactome: R-HSA-975957;Reactome: R-HSA-975956	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"
XP_053989633.1	19	Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-399719;Reactome: R-HSA-3371571	"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Trafficking of AMPA receptors";"HSF1-dependent transactivation"
XP_053978483.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053993794.1	1	Reactome: R-HSA-1237044	"Erythrocytes take up carbon dioxide and release oxygen"
XP_053984380.1	3	Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294	"SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors"
XP_053982777.1	5	Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438	"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic"
XP_053988447.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit"
XP_053974047.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-445095	"Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins"
XP_053980759.1	1	Reactome: R-HSA-1445148	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"
XP_053984759.1	2	Reactome: R-HSA-8856828;Reactome: R-HSA-8856825	"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis"
XP_053992465.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053976697.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053992019.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781	"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression"
XP_053980380.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053994438.1	16	Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-2467813;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174184	"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Separation of Sister Chromatids";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A"
XP_053978119.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053970632.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053980083.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053977368.1	3	MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807	"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis"
XP_053991098.1	6	Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994	"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress"
XP_053992355.1	1	Reactome: R-HSA-5656169	"Termination of translesion DNA synthesis"
XP_053984201.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053993571.1	2	MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10	"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism"
XP_053989023.1	4	KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757	"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines"
XP_053982252.1	1	Reactome: R-HSA-4615885	"SUMOylation of DNA replication proteins"
XP_053975297.1	2	Reactome: R-HSA-8963888;Reactome: R-HSA-8866423	"Chylomicron assembly";"VLDL assembly"
XP_053973663.1	7	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053979168.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053992794.1	1	Reactome: R-HSA-6790901	"rRNA modification in the nucleus and cytosol"
XP_053976811.1	1	Reactome: R-HSA-110320	"Translesion Synthesis by POLH"
XP_053983777.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053986660.1	4	Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712	"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport"
XP_053979530.1	2	Reactome: R-HSA-416993;Reactome: R-HSA-202733	"Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall"
XP_053995068.1	1	Reactome: R-HSA-72163	"mRNA Splicing - Major Pathway"
XP_053982560.1	2	Reactome: R-HSA-73980;Reactome: R-HSA-749476	"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation"
XP_053984907.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053971060.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-5972	"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_053993254.1	8	Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69091	"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Polymerase switching"
XP_053972572.1	4	MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2	"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism"
XP_053991476.1	1	Reactome: R-HSA-2465910	"MASTL Facilitates Mitotic Progression"
XP_053975439.1	1	Reactome: R-HSA-8873719	"RAB geranylgeranylation"
XP_053980299.1	6	MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 00564+2.7.8.5;Reactome: R-HSA-1483166;Reactome: R-HSA-1483148;MetaCyc: PWY-7817	"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Synthesis of PA";"Synthesis of PG";"Type I lipoteichoic acid biosynthesis (S. aureus)"
XP_053985978.1	7	KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;Reactome: R-HSA-389661;Reactome: R-HSA-71403;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;KEGG: 00020+2.3.1.61	"Tryptophan metabolism";"Lysine catabolism";"Glyoxylate metabolism and glycine degradation";"Citric acid cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)"
XP_053983792.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053972806.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_053971062.1	14	KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-8041;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5972	"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Stearate biosynthesis I (animals)"
XP_053972570.1	5	KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661	"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation"
XP_053972493.1	1	Reactome: R-HSA-390648	"Muscarinic acetylcholine receptors"
XP_053980606.1	3	MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689	"Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I"
XP_053979109.1	3	Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081	"Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling"
XP_053975270.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053986955.1	1	Reactome: R-HSA-5689880	"Ub-specific processing proteases"
XP_053986117.1	1	Reactome: R-HSA-3214815	"HDACs deacetylate histones"
XP_053991960.1	7	Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-5620922	"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium"
XP_053993695.1	14	Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-674695	"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events"
XP_053983562.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053985229.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053976135.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053995091.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053984924.1	2	Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053986662.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053992834.1	12	KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5	"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Propanoate metabolism";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)"
XP_053982790.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053991278.1	42	Reactome: R-HSA-212300;Reactome: R-HSA-977225;Reactome: R-HSA-5693565;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-2559582;Reactome: R-HSA-427359;Reactome: R-HSA-171306;Reactome: R-HSA-5693571;Reactome: R-HSA-1912408;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-5578749;Reactome: R-HSA-5250924;Reactome: R-HSA-110329;Reactome: R-HSA-4551638;Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9609690;Reactome: R-HSA-3214858;Reactome: R-HSA-3214847;Reactome: R-HSA-73772;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-110328;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-9616222;Reactome: R-HSA-8939236;Reactome: R-HSA-9018519;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-3214815;Reactome: R-HSA-9610379;Reactome: R-HSA-2299718;Reactome: R-HSA-5334118;Reactome: R-HSA-427389;Reactome: R-HSA-73728;Reactome: R-HSA-69473;Reactome: R-HSA-2559586	"PRC2 methylates histones and DNA";"Amyloid fiber formation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"Senescence-Associated Secretory Phenotype (SASP)";"SIRT1 negatively regulates rRNA expression";"Packaging Of Telomere Ends";"Nonhomologous End-Joining (NHEJ)";"Pre-NOTCH Transcription and Translation";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Transcriptional regulation by small RNAs";"B-WICH complex positively regulates rRNA expression";"Cleavage of the damaged pyrimidine";"SUMOylation of chromatin organization proteins";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"HCMV Early Events";"RMTs methylate histone arginines";"HATs acetylate histones";"RNA Polymerase I Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Estrogen-dependent gene expression";"Meiotic recombination";"Meiotic synapsis";"HDACs deacetylate histones";"HCMV Late Events";"Condensation of Prophase Chromosomes";"DNA methylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Opening";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence"
XP_053973570.1	2	Reactome: R-HSA-8866423;Reactome: R-HSA-8963888	"VLDL assembly";"Chylomicron assembly"
XP_053989005.1	13	Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-6791226	"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053975077.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053981373.1	4	Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187	"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing"
XP_053971188.1	2	Reactome: R-HSA-430039;Reactome: R-HSA-72163	"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway"
XP_053975968.1	2	Reactome: R-HSA-3214847;Reactome: R-HSA-6804758	"HATs acetylate histones";"Regulation of TP53 Activity through Acetylation"
XP_053976357.1	1	Reactome: R-HSA-112126	"ALKBH3 mediated reversal of alkylation damage"
XP_053988408.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053974008.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053994241.1	17	Reactome: R-HSA-200425;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5789;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-6722;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381	"Carnitine metabolism";"Aflatoxin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Propanoate metabolism";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism";"Jadomycin biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)"
XP_053993771.1	3	MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546	"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)"
XP_053990431.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053972797.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_053971843.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053989411.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053975880.1	1	Reactome: R-HSA-2151201	"Transcriptional activation of mitochondrial biogenesis"
XP_053979414.1	6	MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107	"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Glycerophospholipid metabolism"
XP_053992594.1	2	Reactome: R-HSA-72163;Reactome: R-HSA-72165	"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway"
XP_053983577.1	1	Reactome: R-HSA-8955332	"Carboxyterminal post-translational modifications of tubulin"
XP_053992578.1	16	Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-6811558;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-194840;Reactome: R-HSA-912631;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-114604;Reactome: R-HSA-1433557	"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Rho GTPase cycle";"Regulation of signaling by CBL";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"RET signaling";"GPVI-mediated activation cascade";"Signaling by SCF-KIT"
XP_053985070.1	2	Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77	"Methionine salvage pathway";"Cysteine and methionine metabolism"
XP_053984559.1	2	Reactome: R-HSA-3108214;Reactome: R-HSA-5685938	"SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)"
XP_053975188.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053985373.1	1	Reactome: R-HSA-5658442	"Regulation of RAS by GAPs"
XP_053971077.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053981262.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053971968.1	2	Reactome: R-HSA-181429;Reactome: R-HSA-212676	"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle"
XP_053986053.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053970902.1	1	Reactome: R-HSA-2132295	"MHC class II antigen presentation"
XP_053993594.1	1	Reactome: R-HSA-110362	"POLB-Dependent Long Patch Base Excision Repair"
XP_053980893.1	2	Reactome: R-HSA-9010553;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053975062.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053993578.1	22	Reactome: R-HSA-196299;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5467340;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-195253	"Beta-catenin phosphorylation cascade";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Separation of Sister Chromatids";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RAF activation";"Degradation of beta-catenin by the destruction complex"
XP_053994044.1	4	Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-975957	"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"
XP_053982954.1	1	KEGG: 04070+2.7.11.13	"Phosphatidylinositol signaling system"
XP_053971270.1	2	Reactome: R-HSA-204005;Reactome: R-HSA-8876198	"COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs"
XP_053973797.1	6	Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-6731;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.1;MetaCyc: PWY-6737	"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch degradation III";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V"
XP_053980559.1	1	Reactome: R-HSA-5250924	"B-WICH complex positively regulates rRNA expression"
XP_053977451.1	1	Reactome: R-HSA-169911	"Regulation of Apoptosis"
XP_053995116.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053987454.1	1	Reactome: R-HSA-70221	"Glycogen breakdown (glycogenolysis)"
XP_053979205.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053994000.1	2	Reactome: R-HSA-3238698;Reactome: R-HSA-373080	"WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)"
XP_053991091.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053975639.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053989706.1	1	Reactome: R-HSA-6798163	"Choline catabolism"
XP_053989903.1	5	MetaCyc: PWY-6168;MetaCyc: PWY-7863;MetaCyc: PWY-5523;Reactome: R-HSA-196843;KEGG: 00740+2.7.1.26	"Flavin biosynthesis III (fungi)";"Roseoflavin biosynthesis";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Riboflavin metabolism"
XP_053991180.1	1	Reactome: R-HSA-432047	"Passive transport by Aquaporins"
XP_053994431.1	13	Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9633012	"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency"
XP_053981067.1	7	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis"
XP_053975060.1	2	Reactome: R-HSA-1296052;Reactome: R-HSA-418457	"Ca2+ activated K+ channels";"cGMP effects"
XP_053978934.1	1	Reactome: R-HSA-2022377	"Metabolism of Angiotensinogen to Angiotensins"
XP_053975453.1	1	Reactome: R-HSA-5693568	"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053971272.1	182	Reactome: R-HSA-937042;Reactome: R-HSA-75815;Reactome: R-HSA-72764;Reactome: R-HSA-445989;Reactome: R-HSA-2691232;Reactome: R-HSA-9637628;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-1799339;Reactome: R-HSA-2122948;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-5696394;Reactome: R-HSA-9613829;Reactome: R-HSA-8849469;Reactome: R-HSA-937041;Reactome: R-HSA-110312;Reactome: R-HSA-2672351;Reactome: R-HSA-6781827;Reactome: R-HSA-2644606;Reactome: R-HSA-6783310;Reactome: R-HSA-168928;Reactome: R-HSA-69231;Reactome: R-HSA-9013507;Reactome: R-HSA-72649;Reactome: R-HSA-937039;Reactome: R-HSA-977225;Reactome: R-HSA-8866654;Reactome: R-HSA-8876493;Reactome: R-HSA-1169408;Reactome: R-HSA-5656121;Reactome: R-HSA-2122947;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827;Reactome: R-HSA-5675482;Reactome: R-HSA-2979096;Reactome: R-HSA-5654732;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-72702;Reactome: R-HSA-936964;Reactome: R-HSA-6804757;Reactome: R-HSA-5654727;Reactome: R-HSA-180534;Reactome: R-HSA-9636383;Reactome: R-HSA-2173795;Reactome: R-HSA-192823;Reactome: R-HSA-8854050;Reactome: R-HSA-975163;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-174048;Reactome: R-HSA-202424;Reactome: R-HSA-5696395;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-201681;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-532668;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5357956;Reactome: R-HSA-8866652;Reactome: R-HSA-5684264;Reactome: R-HSA-5693607;Reactome: R-HSA-901032;Reactome: R-HSA-72695;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-5655862;Reactome: R-HSA-209543;Reactome: R-HSA-9013973;Reactome: R-HSA-450321;Reactome: R-HSA-1236974;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-6791226;Reactome: R-HSA-917937;Reactome: R-HSA-174154;Reactome: R-HSA-5696397;Reactome: R-HSA-182971;Reactome: R-HSA-2173788;Reactome: R-HSA-5693565;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-5205685;Reactome: R-HSA-9615710;Reactome: R-HSA-8863795;Reactome: R-HSA-9646399;Reactome: R-HSA-4641263;Reactome: R-HSA-5676590;Reactome: R-HSA-9645460;Reactome: R-HSA-5689901;Reactome: R-HSA-1169091;Reactome: R-HSA-400253;Reactome: R-HSA-1236382;Reactome: R-HSA-8951664;Reactome: R-HSA-9033241;Reactome: R-HSA-5610783;Reactome: R-HSA-187577;Reactome: R-HSA-175474;Reactome: R-HSA-6804760;Reactome: R-HSA-8948747;Reactome: R-HSA-3785653;Reactome: R-HSA-1295596;Reactome: R-HSA-3322077;Reactome: R-HSA-180585;Reactome: R-HSA-69541;Reactome: R-HSA-4641258;Reactome: R-HSA-5689877;Reactome: R-HSA-5675221;Reactome: R-HSA-3769402;Reactome: R-HSA-912631;Reactome: R-HSA-4608870;Reactome: R-HSA-1358803;Reactome: R-HSA-937072;Reactome: R-HSA-5357905;Reactome: R-HSA-2173791;Reactome: R-HSA-9633012;Reactome: R-HSA-68949;Reactome: R-HSA-110314;Reactome: R-HSA-975957;Reactome: R-HSA-2565942;Reactome: R-HSA-110320;Reactome: R-HSA-6782210;Reactome: R-HSA-382556;Reactome: R-HSA-6782135;Reactome: R-HSA-8875360;Reactome: R-HSA-2559585;Reactome: R-HSA-2559582;Reactome: R-HSA-4641257;Reactome: R-HSA-156902;Reactome: R-HSA-5689603;Reactome: R-HSA-1253288;Reactome: R-HSA-72689;Reactome: R-HSA-6781823;Reactome: R-HSA-6807004;Reactome: R-HSA-174178;Reactome: R-HSA-2173796;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5656169;Reactome: R-HSA-5654733;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-5696400;Reactome: R-HSA-3134975;Reactome: R-HSA-156827;Reactome: R-HSA-975110;Reactome: R-HSA-2408557;Reactome: R-HSA-209560;Reactome: R-HSA-211733;Reactome: R-HSA-8856825;Reactome: R-HSA-168638;Reactome: R-HSA-9014325;Reactome: R-HSA-450302;Reactome: R-HSA-5689896;Reactome: R-HSA-174490;Reactome: R-HSA-5607761;Reactome: R-HSA-5654726;Reactome: R-HSA-6804756;Reactome: R-HSA-917729;Reactome: R-HSA-5685942;Reactome: R-HSA-162588;Reactome: R-HSA-975144;Reactome: R-HSA-168927;Reactome: R-HSA-8856828;Reactome: R-HSA-1234176;Reactome: R-HSA-2894862;Reactome: R-HSA-936440;Reactome: R-HSA-205043;Reactome: R-HSA-2467813	"IRAK2 mediated activation of TAK1 complex";"Ubiquitin-dependent degradation of Cyclin D";"Eukaryotic Translation Termination";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Modulation by Mtb of host immune system";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"SRP-dependent cotranslational protein targeting to membrane";"Activated NOTCH1 Transmits Signal to the Nucleus";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"DNA Damage Recognition in GG-NER";"Chaperone Mediated Autophagy";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"IKK complex recruitment mediated by RIP1";"Translesion synthesis by REV1";"Stimuli-sensing channels";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Fanconi Anemia Pathway";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Cyclin D associated events in G1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Translation initiation complex formation";"IRAK1 recruits IKK complex";"Amyloid fiber formation";"E3 ubiquitin ligases ubiquitinate target proteins";"InlA-mediated entry of Listeria monocytogenes into host cells";"ISG15 antiviral mechanism";"Translesion synthesis by POLI";"NOTCH1 Intracellular Domain Regulates Transcription";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of necroptotic cell death";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Negative regulation of FGFR3 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Ribosomal scanning and start codon recognition";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Regulation of TP53 Degradation";"Negative regulation of FGFR2 signaling";"Vpu mediated degradation of CD4";"Prevention of phagosomal-lysosomal fusion";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Viral mRNA Translation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Downstream TCR signaling";"Formation of Incision Complex in GG-NER";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"TCF dependent signaling in response to WNT";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"TNFR1-induced NFkappaB signaling pathway";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Processing of DNA double-strand break ends";"ER Quality Control Compartment (ERQC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Translesion synthesis by POLK";"p75NTR recruits signalling complexes";"TICAM1-dependent activation of IRF3/IRF7";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"ER-Phagosome pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Major pathway of rRNA processing in the nucleolus and cytosol";"Iron uptake and transport";"APC/C:Cdc20 mediated degradation of Securin";"Gap-filling DNA repair synthesis and ligation in GG-NER";"EGFR downregulation";"Downregulation of TGF-beta receptor signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Pink/Parkin Mediated Mitophagy";"Late endosomal microautophagy";"Downregulation of ERBB2 signaling";"Aggrephagy";"Regulation of FZD by ubiquitination";"NIK-->noncanonical NF-kB signaling";"Alpha-protein kinase 1 signaling pathway";"Metalloprotease DUBs";"Activation of NF-kappaB in B cells";"Circadian Clock";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Neddylation";"Peroxisomal protein import";"Degradation of GLI2 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Assembly Of The HIV Virion";"Regulation of TP53 Activity through Methylation";"Regulation of PTEN localization";"Myoclonic epilepsy of Lafora";"Spry regulation of FGF signaling";"Glycogen synthesis";"Vif-mediated degradation of APOBEC3G";"Stabilization of p53";"Degradation of DVL";"Josephin domain DUBs";"Negative regulation of MAPK pathway";"Deactivation of the beta-catenin transactivating complex";"Regulation of signaling by CBL";"Asymmetric localization of PCP proteins";"Downregulation of ERBB2:ERBB3 signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Regulation of TNFR1 signaling";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Orc1 removal from chromatin";"Recognition of DNA damage by PCNA-containing replication complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of PLK1 Activity at G2/M Transition";"Translesion Synthesis by POLH";"Gap-filling DNA repair synthesis and ligation in TC-NER";"ABC-family proteins mediated transport";"Dual incision in TC-NER";"InlB-mediated entry of Listeria monocytogenes into host cell";"Oncogene Induced Senescence";"Senescence-Associated Secretory Phenotype (SASP)";"Degradation of AXIN";"Peptide chain elongation";"UCH proteinases";"Downregulation of ERBB4 signaling";"Formation of a pool of free 40S subunits";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of MET activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Termination of translesion DNA synthesis";"Negative regulation of FGFR4 signaling";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Dual Incision in GG-NER";"Regulation of innate immune responses to cytosolic DNA";"L13a-mediated translational silencing of Ceruloplasmin expression";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Selenocysteine synthesis";"NF-kB is activated and signals survival";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Cargo recognition for clathrin-mediated endocytosis";"NOD1/2 Signaling Pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"activated TAK1 mediates p38 MAPK activation";"Ovarian tumor domain proteases";"Membrane binding and targetting of GAG proteins";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of FGFR1 signaling";"Regulation of TP53 Activity through Phosphorylation";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HDR through Homologous Recombination (HRR)";"Budding and maturation of HIV virion";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"TICAM1, RIP1-mediated IKK complex recruitment";"Clathrin-mediated endocytosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Negative regulators of DDX58/IFIH1 signaling";"NRIF signals cell death from the nucleus";"Separation of Sister Chromatids"
XP_053973549.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053980518.1	14	MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-5981;MetaCyc: PWY-7589	"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Palmitoleate biosynthesis III (cyanobacteria)"
XP_053984941.1	1	Reactome: R-HSA-6803157	"Antimicrobial peptides"
XP_053972693.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053994002.1	2	Reactome: R-HSA-373080;Reactome: R-HSA-3238698	"Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking"
XP_053974714.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053978151.1	6	Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877	"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase"
XP_053991182.1	2	Reactome: R-HSA-380320;Reactome: R-HSA-380270	"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes"
XP_053991977.1	6	Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450604	"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA"
XP_053990002.1	1	Reactome: R-HSA-5419276	"Mitochondrial translation termination"
XP_053985750.1	3	Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340	"Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053992106.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053985072.1	10	KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-8001;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041	"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle"
XP_053972567.1	4	Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261	"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis"
XP_053988311.1	2	Reactome: R-HSA-1483166;Reactome: R-HSA-1483148	"Synthesis of PA";"Synthesis of PG"
XP_053981260.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053993051.1	2	MetaCyc: PWY-5697;KEGG: 00230+3.5.3.4	"Allantoin degradation to ureidoglycolate I (urea producing)";"Purine metabolism"
XP_053992764.1	11	Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-5659;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;MetaCyc: PWY-6992	"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Mannitol biosynthesis";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation"
XP_053970900.1	1	Reactome: R-HSA-9617828	"FOXO-mediated transcription of cell cycle genes"
XP_053975267.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053984733.1	2	Reactome: R-HSA-195253;Reactome: R-HSA-5689896	"Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases"
XP_053989867.1	3	Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902	"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity"
XP_053980316.1	4	Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing"
XP_053984985.1	1	Reactome: R-HSA-5620924	"Intraflagellar transport"
XP_053992826.1	4	KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;MetaCyc: PWY-6902	"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)"
XP_053984936.1	5	MetaCyc: PWY-7536;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37	"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Glycine, serine and threonine metabolism"
XP_053995098.1	17	Reactome: R-HSA-5696397;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-174417;Reactome: R-HSA-5358565;Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-110314	"Gap-filling DNA repair synthesis and ligation in GG-NER";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex"
XP_053970928.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053979988.1	7	Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-5628897;Reactome: R-HSA-165181	"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB"
XP_053993950.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053982590.1	3	Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276	"Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination"
XP_053980004.1	1	Reactome: R-HSA-428359	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"
XP_053978215.1	7	Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380284	"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome"
XP_053994173.1	1	Reactome: R-HSA-426048	"Arachidonate production from DAG"
XP_053985290.1	4	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates"
XP_053970430.1	3	Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1	"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway"
XP_053988913.1	10	Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-912446	"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Meiotic recombination"
XP_053981184.1	17	Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167158;Reactome: R-HSA-113418;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-112382;KEGG: 04660+3.1.3.16	"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Th1 and Th2 cell differentiation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"T cell receptor signaling pathway"
XP_053985097.1	4	KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;MetaCyc: PWY-6483	"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Ceramide degradation (generic)"
XP_053988030.1	6	Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-388844	"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases"
XP_053982729.1	2	Reactome: R-HSA-5696394;Reactome: R-HSA-5689603	"DNA Damage Recognition in GG-NER";"UCH proteinases"
XP_053988333.1	3	MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21	"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system"
XP_053994248.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053980269.1	3	Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2	"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway"
XP_053974001.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053972052.1	2	KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053989659.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053993826.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053974928.1	1	Reactome: R-HSA-983231	"Factors involved in megakaryocyte development and platelet production"
XP_053972770.1	2	Reactome: R-HSA-525793;Reactome: R-HSA-373752	"Myogenesis";"Netrin-1 signaling"
XP_053992950.1	56	Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174154;Reactome: R-HSA-8854050	"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis"
XP_053980936.1	26	Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-3371497;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5626467;Reactome: R-HSA-389977;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025	"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Gap junction assembly";"Recycling pathway of L1";"Mitotic Prometaphase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"RHO GTPases activate IQGAPs";"Post-chaperonin tubulin folding pathway";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation"
XP_053984343.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053985103.1	4	Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-352230	"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Tryptophan catabolism";"Amino acid transport across the plasma membrane"
XP_053984316.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053980247.1	2	Reactome: R-HSA-8873719;Reactome: R-HSA-6803205	"RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"
XP_053972463.1	3	Reactome: R-HSA-3214841;Reactome: R-HSA-8936459;Reactome: R-HSA-383280	"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nuclear Receptor transcription pathway"
XP_053988032.1	6	Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181429	"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle"
XP_053987101.1	2	Reactome: R-HSA-4086398;Reactome: R-HSA-418457	"Ca2+ pathway";"cGMP effects"
XP_053983146.1	4	Reactome: R-HSA-6782315;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285	"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis"
XP_053989301.1	1	Reactome: R-HSA-435368	"Zinc efflux and compartmentalization by the SLC30 family"
XP_053984220.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053984637.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053977963.1	6	Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930	"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor"
XP_053972772.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053995061.1	1	Reactome: R-HSA-6784531	"tRNA processing in the nucleus"
XP_053992952.1	56	Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-68827	"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CDT1 association with the CDC6:ORC:origin complex"
XP_053984042.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053973257.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053987265.1	3	KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161	"Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation"
XP_053974615.1	1	KEGG: 00970+6.1.1.21	"Aminoacyl-tRNA biosynthesis"
XP_053993665.1	9	Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-110328;Reactome: R-HSA-9608290;Reactome: R-HSA-9608287;Reactome: R-HSA-110331;Reactome: R-HSA-110330	"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective MUTYH substrate processing";"Defective MUTYH substrate binding";"Cleavage of the damaged purine";"Recognition and association of DNA glycosylase with site containing an affected purine"
XP_053988669.1	6	Reactome: R-HSA-5609978;MetaCyc: PWY-6527;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317	"Defective GALT can cause Galactosemia";"Stachyose degradation";"Galactose catabolism";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)"
XP_053973353.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6	"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism"
XP_053970615.1	9	Reactome: R-HSA-165159;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972	"mTOR signalling";"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Neutrophil degranulation";"MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK"
XP_053982146.1	4	Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75	"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis"
XP_053991264.1	5	KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043	"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis"
XP_053982113.1	1	Reactome: R-HSA-2022928	"HS-GAG biosynthesis"
XP_053984027.1	7	KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053973463.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053980637.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053993952.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053977658.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053992665.1	2	KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10	"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism"
XP_053982592.1	12	KEGG: 00010+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00051+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171	"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Fructose and mannose metabolism";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis"
XP_053983489.1	2	Reactome: R-HSA-5576892;Reactome: R-HSA-5576893	"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase"
XP_053972257.1	6	Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949	"Unwinding of DNA";"Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin"
XP_053985292.1	4	Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221	"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis"
XP_053985971.1	1	Reactome: R-HSA-162710	"Synthesis of glycosylphosphatidylinositol (GPI)"
XP_053975557.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053994638.1	7	MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7	"Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis"
XP_053979730.1	1	Reactome: R-HSA-3214841	"PKMTs methylate histone lysines"
XP_053977196.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053991237.1	1	Reactome: R-HSA-5689877	"Josephin domain DUBs"
XP_053983898.1	29	Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-73762;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782210;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-77075	"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase I Transcription Initiation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE"
XP_053992897.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053986947.1	12	KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1	"Human papillomavirus infection";"Rho GTPase cycle";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"Relaxin signaling pathway";"NRAGE signals death through JNK";"mTOR signaling pathway";"Signaling by FGFR1 in disease";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection"
XP_053991946.1	5	Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710	"Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy"
XP_053970556.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920	"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability"
XP_053977405.1	2	MetaCyc: PWY-6854;Reactome: R-HSA-3299685	"Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species"
XP_053976983.1	1	Reactome: R-HSA-8854691	"Interleukin-20 family signaling"
XP_053989254.1	2	KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936	"Indole alkaloid biosynthesis";"Psilocybin biosynthesis"
XP_053977542.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053979396.1	1	Reactome: R-HSA-8949613	"Cristae formation"
XP_053985636.1	57	Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-6798695;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-9020702;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-69481;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-5610783;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-5610780;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180534;Reactome: R-HSA-8948751;Reactome: R-HSA-5678895;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-1234176;Reactome: R-HSA-4641257;Reactome: R-HSA-5607764;Reactome: R-HSA-2467813;Reactome: R-HSA-5632684;Reactome: R-HSA-69601;Reactome: R-HSA-450408;Reactome: R-HSA-349425;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-174113;Reactome: R-HSA-68949	"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Neutrophil degranulation";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Interleukin-1 signaling";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"G2/M Checkpoints";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI2 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vpu mediated degradation of CD4";"Regulation of PTEN stability and activity";"Defective CFTR causes cystic fibrosis";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of AXIN";"CLEC7A (Dectin-1) signaling";"Separation of Sister Chromatids";"Hedgehog 'on' state";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Autodegradation of the E3 ubiquitin ligase COP1";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin"
XP_053973084.1	6	Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-983168;Reactome: R-HSA-2173788	"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of TGF-beta receptor signaling"
XP_053981819.1	7	Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518	"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2"
XP_053985026.1	7	MetaCyc: PWY-7456;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8	"Beta-(1,4)-mannan degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism"
XP_053988992.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053982307.1	1	Reactome: R-HSA-156588	"Glucuronidation"
XP_053981238.1	3	MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1	"Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis"
XP_053976345.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053976228.1	1	Reactome: R-HSA-1799339	"SRP-dependent cotranslational protein targeting to membrane"
XP_053974661.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053977214.1	5	MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;MetaCyc: PWY-7919	"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)"
XP_053986922.1	2	Reactome: R-HSA-418594;Reactome: R-HSA-6814122	"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053981152.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053983203.1	22	MetaCyc: PWY-7049;MetaCyc: PWY-6433;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5353;MetaCyc: PWY-7606;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7592;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7726;MetaCyc: PWY-7728;MetaCyc: PWY-8041	"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis"
XP_053993005.1	2	Reactome: R-HSA-1296072;Reactome: R-HSA-5576894	"Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels"
XP_053981858.1	1	Reactome: R-HSA-8964038	"LDL clearance"
XP_053983324.1	2	Reactome: R-HSA-3214858;Reactome: R-HSA-8939243	"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"
XP_053982546.1	1	Reactome: R-HSA-420499	"Class C/3 (Metabotropic glutamate/pheromone receptors)"
XP_053987708.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053991669.1	56	Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5610780;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-8939236;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-8939902;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-1236974;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-4608870	"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI1 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX2 expression and activity";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"ER-Phagosome pathway";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins"
XP_053988990.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053985246.1	4	Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-3000170	"Integrin cell surface interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Syndecan interactions"
XP_053986646.1	1	Reactome: R-HSA-5368286	"Mitochondrial translation initiation"
XP_053983861.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053981150.1	1	Reactome: R-HSA-112308	"Presynaptic depolarization and calcium channel opening"
XP_053980671.1	2	Reactome: R-HSA-2022928;MetaCyc: PWY-6558	"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)"
XP_053975157.1	5	KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-5083	"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation"
XP_053991622.1	6	Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385	"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"
XP_053990492.1	1	KEGG: 00970+6.1.1.20	"Aminoacyl-tRNA biosynthesis"
XP_053987501.1	1	Reactome: R-HSA-6798695	"Neutrophil degranulation"
XP_053979831.1	6	MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107	"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism"
XP_053978105.1	4	Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722	"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex"
XP_053986856.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053983546.1	1	Reactome: R-HSA-606279	"Deposition of new CENPA-containing nucleosomes at the centromere"
XP_053977540.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053982861.1	1	Reactome: R-HSA-426117	"Cation-coupled Chloride cotransporters"
XP_053972864.1	3	Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-194840	"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Rho GTPase cycle"
XP_053975386.1	2	Reactome: R-HSA-6791226;Reactome: R-HSA-6790901	"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol"
XP_053988264.1	1	Reactome: R-HSA-156584	"Cytosolic sulfonation of small molecules"
XP_053980765.1	4	Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052	"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion"
XP_053972923.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053976634.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053979561.1	1	Reactome: R-HSA-425986	"Sodium/Proton exchangers"
XP_053980159.1	26	Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-69205;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-5358606;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-1362277;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-4615885;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-6782135;Reactome: R-HSA-8866654;Reactome: R-HSA-6804114;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-174411	"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"G1/S-Specific Transcription";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Transcription of E2F targets under negative control by DREAM complex";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"SUMOylation of DNA replication proteins";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Dual incision in TC-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Translesion synthesis by POLI";"Polymerase switching";"Polymerase switching on the C-strand of the telomere"
XP_053981703.1	1	Reactome: R-HSA-6783310	"Fanconi Anemia Pathway"
XP_053977423.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053988455.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053973288.1	7	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053992322.1	5	Reactome: R-HSA-4755579;KEGG: 00510+1.3.1.94;Reactome: R-HSA-446199;MetaCyc: PWY-6129;Reactome: R-HSA-193048	"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Dolichol and dolichyl phosphate biosynthesis";"Androgen biosynthesis"
XP_053982531.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436	"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway"
XP_053976895.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053988365.1	12	KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1	"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"mTOR signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection"
XP_053975234.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053991580.1	9	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053985231.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053981624.1	1	Reactome: R-HSA-381753	"Olfactory Signaling Pathway"
XP_053988091.1	5	Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571	"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)"
XP_053984494.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053978078.1	5	Reactome: R-HSA-3371571;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-198323	"HSF1-dependent transactivation";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"AKT phosphorylates targets in the cytosol"
XP_053976202.1	1	Reactome: R-HSA-3214847	"HATs acetylate histones"
XP_053983225.1	2	Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1	"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053985407.1	2	Reactome: R-HSA-6798695;Reactome: R-HSA-8964038	"Neutrophil degranulation";"LDL clearance"
XP_053983177.1	8	Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-7199	"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides salvage"
XP_053992178.1	13	MetaCyc: PWY-7210;MetaCyc: PWY-7226;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7220;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198	"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV"
XP_053984812.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053992194.1	8	Reactome: R-HSA-917977;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712	"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport"
XP_053982738.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053992870.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053974266.1	13	KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-2029485;MetaCyc: PWY-6367;Reactome: R-HSA-9027277;Reactome: R-HSA-2424491;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-202433;Reactome: R-HSA-2871809;Reactome: R-HSA-2871796;MetaCyc: PWY-6351	"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis";"D-myo-inositol-5-phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"DAP12 signaling";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Generation of second messenger molecules";"FCERI mediated Ca+2 mobilization";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis"
XP_053993216.1	9	Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533	"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Drug metabolism - other enzymes";"Glutathione metabolism";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis"
XP_053987720.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053993243.1	1	Reactome: R-HSA-936837	"Ion transport by P-type ATPases"
XP_053979475.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053975588.1	7	Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490	"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation"
XP_053977687.1	2	Reactome: R-HSA-6783310;Reactome: R-HSA-5693568	"Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates"
XP_053972288.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053992459.1	1	Reactome: R-HSA-203754	"NOSIP mediated eNOS trafficking"
XP_053975602.1	1	Reactome: R-HSA-390696	"Adrenoceptors"
XP_053981441.1	5	Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72187	"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing"
XP_053976024.1	1	Reactome: R-HSA-204626	"Hypusine synthesis from eIF5A-lysine"
XP_053983531.1	2	Reactome: R-HSA-5682910;Reactome: R-HSA-5250971	"LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)"
XP_053982982.1	1	Reactome: R-HSA-380320	"Recruitment of NuMA to mitotic centrosomes"
XP_053984765.1	9	Reactome: R-HSA-196780;MetaCyc: PWY-8086;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-70263;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00620+6.4.1.1	"Biotin transport and metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Pyruvate metabolism"
XP_053993322.1	13	Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-437239	"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"LDL clearance";"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Recycling pathway of L1"
XP_053991154.1	2	Reactome: R-HSA-983189;Reactome: R-HSA-6811434	"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053994662.1	1	Reactome: R-HSA-3214858	"RMTs methylate histone arginines"
XP_053989137.1	1	Reactome: R-HSA-381038	"XBP1(S) activates chaperone genes"
XP_053992633.1	1	Reactome: R-HSA-1268020	"Mitochondrial protein import"
XP_053970468.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053984810.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053987722.1	1	Reactome: R-HSA-913709	"O-linked glycosylation of mucins"
XP_053971545.1	2	Reactome: R-HSA-977443;Reactome: R-HSA-1236394	"GABA receptor activation";"Signaling by ERBB4"
XP_053986241.1	1	Reactome: R-HSA-8951664	"Neddylation"
XP_053972167.1	3	MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646	"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification"
XP_053984118.1	3	MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581	"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis"
XP_053993023.1	13	Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764	"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination"
XP_053981607.1	10	KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3214847;KEGG: 04714+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1	"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"HATs acetylate histones";"Thermogenesis";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway"
XP_053987337.1	9	Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809	"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"Rho GTPase cycle";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization"
XP_053979957.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053978758.1	1	Reactome: R-HSA-212436	"Generic Transcription Pathway"
XP_053993320.1	13	Reactome: R-HSA-177504;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-437239;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-8856828;Reactome: R-HSA-5140745;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825	"Retrograde neurotrophin signalling";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Recycling pathway of L1";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"LDL clearance";"VLDLR internalisation and degradation";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis"
XP_053982980.1	5	Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729	"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)"
XP_053993633.1	30	Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-2564830;Reactome: R-HSA-73776;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167160;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-112382	"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex"
XP_053972612.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053989465.1	6	MetaCyc: PWY-4261;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3	"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Synthesis of PA";"Glycerophospholipid metabolism"
XP_053976193.1	1	Reactome: R-HSA-390522	"Striated Muscle Contraction"
XP_053984276.1	9	Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053982045.1	11	Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519	"Generic Transcription Pathway";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression"
XP_053994955.1	3	MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217	"Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage"
XP_053977783.1	33	Reactome: R-HSA-168325;Reactome: R-HSA-6784531;Reactome: R-HSA-2467813;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-168276	"Viral Messenger RNA Synthesis";"tRNA processing in the nucleus";"Separation of Sister Chromatids";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"SUMOylation of RNA binding proteins";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways"
XP_053977935.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053980118.1	10	MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11	"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Galactose metabolism"
XP_053989355.1	3	Reactome: R-HSA-9609690;Reactome: R-HSA-6804757;Reactome: R-HSA-3899300	"HCMV Early Events";"Regulation of TP53 Degradation";"SUMOylation of transcription cofactors"
XP_053985424.1	1	Reactome: R-HSA-977347	"Serine biosynthesis"
XP_053982417.1	6	Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68949	"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Orc1 removal from chromatin"
XP_053985851.1	3	Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation"
XP_053992320.1	1	Reactome: R-HSA-203927	"MicroRNA (miRNA) biogenesis"
XP_053980595.1	1	Reactome: R-HSA-1221632	"Meiotic synapsis"
XP_053990662.1	1	Reactome: R-HSA-9609523	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"
XP_053978666.1	14	KEGG: 00600+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;MetaCyc: PWY-7782;Reactome: R-HSA-1483191;MetaCyc: PWY-8055;Reactome: R-HSA-75109;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;KEGG: 00565+3.1.3.4;MetaCyc: PWY-6453	"Sphingolipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Synthesis of PC";"Palmitoyl ethanolamide biosynthesis";"Triglyceride biosynthesis";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Anandamide biosynthesis I";"Ether lipid metabolism";"Stigma estolide biosynthesis"
XP_053989778.1	1	Reactome: R-HSA-9639288	"Amino acids regulate mTORC1"
XP_053988977.1	4	KEGG: 00970+6.1.1.18;Reactome: R-HSA-379716;Reactome: R-HSA-379726;Reactome: R-HSA-2408522	"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism"
XP_053991582.1	9	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1	"Human cytomegalovirus infection";"Human papillomavirus infection";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis"
XP_053988554.1	12	Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878	"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"COPI-mediated anterograde transport"
XP_053979791.1	2	Reactome: R-HSA-5689880;Reactome: R-HSA-5689896	"Ub-specific processing proteases";"Ovarian tumor domain proteases"
XP_053978123.1	1	Reactome: R-HSA-5610787	"Hedgehog 'off' state"
XP_053972435.1	3	Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339	"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane"
XP_053988655.1	18	Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-166208;Reactome: R-HSA-192823	"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"mTORC1-mediated signalling";"Viral mRNA Translation"
XP_053977910.1	17	KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-176187;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-69473;Reactome: R-HSA-1433557;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8953750;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-75035;Reactome: R-HSA-6796648	"Human cytomegalovirus infection";"Human papillomavirus infection";"Activation of ATR in response to replication stress";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"G2/M DNA damage checkpoint";"Signaling by SCF-KIT";"Relaxin signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Transcriptional Regulation by E2F6";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Transcription of DNA Repair Genes"
XP_053976041.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053981424.1	7	Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749	"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs"
XP_053971421.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053990350.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053992282.1	33	Reactome: R-HSA-6784531;Reactome: R-HSA-168325;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-159230;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-4570464;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-168276	"tRNA processing in the nucleus";"Viral Messenger RNA Synthesis";"Separation of Sister Chromatids";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP Dependant Mature mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of RNA binding proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways"
XP_053992849.1	1	Reactome: R-HSA-912446	"Meiotic recombination"
XP_053973245.1	1	KEGG: 00970+6.1.1.2	"Aminoacyl-tRNA biosynthesis"
XP_053976434.1	6	Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513	"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA"
XP_053973328.1	2	Reactome: R-HSA-5083635;Reactome: R-HSA-5173214	"Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins"
XP_053973987.1	2	MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8	"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism"
XP_053979456.1	4	Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664	"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation"
XP_053983746.1	2	Reactome: R-HSA-375276;Reactome: R-HSA-416476	"Peptide ligand-binding receptors";"G alpha (q) signalling events"
XP_053980835.1	3	Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340	"PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation"
XP_053986000.1	5	Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-5221030;Reactome: R-HSA-110328	"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine"
XP_053983916.1	2	Reactome: R-HSA-983168;MetaCyc: PWY-7511	"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination"
XP_053990677.1	1	Reactome: R-HSA-162791	"Attachment of GPI anchor to uPAR"
XP_053995154.1	11	KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170670	"Purine metabolism";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (s) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway"
XP_053983385.1	3	Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840	"Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation"
XP_053992925.1	2	Reactome: R-HSA-429947;Reactome: R-HSA-6804115	"Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"
XP_053979675.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053979130.1	2	Reactome: R-HSA-6790901;Reactome: R-HSA-6791226	"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053981641.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053988962.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053993867.1	1	Reactome: R-HSA-191859	"snRNP Assembly"
XP_053984694.1	5	Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855	"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)"
XP_053975545.1	2	Reactome: R-HSA-5218920;Reactome: R-HSA-418990	"VEGFR2 mediated vascular permeability";"Adherens junctions interactions"
XP_053974691.1	2	Reactome: R-HSA-2151201;Reactome: R-HSA-400253	"Transcriptional activation of mitochondrial biogenesis";"Circadian Clock"
XP_053994350.1	5	Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588	"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion"
XP_053994053.1	5	Reactome: R-HSA-9646399;Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5689877	"Aggrephagy";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Josephin domain DUBs"
XP_053979219.1	16	Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-180585;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-8951664	"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Vif-mediated degradation of APOBEC3G";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Neddylation"
XP_053988845.1	24	Reactome: R-HSA-418592;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-392451;Reactome: R-HSA-392170;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-416476;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-381676;Reactome: R-HSA-202040;Reactome: R-HSA-6814122	"ADP signalling through P2Y purinoceptor 1";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PI3Kgamma";"ADP signalling through P2Y purinoceptor 12";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G alpha (q) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (s) signalling events";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"
XP_053994460.1	3	KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271	"Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism"
XP_053985607.1	1	Reactome: R-HSA-189085	"Digestion of dietary carbohydrate"
XP_053977330.1	3	Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840	"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation"
XP_053972328.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053972245.1	1	Reactome: R-HSA-2672351	"Stimuli-sensing channels"
XP_053991699.1	3	Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961	"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II"
XP_053985034.1	1	MetaCyc: PWY-7511	"Protein ubiquitination"
XP_053989376.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053983617.1	1	Reactome: R-HSA-1632852	"Macroautophagy"
XP_053992618.1	2	Reactome: R-HSA-5173214;Reactome: R-HSA-5083635	"O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)"
XP_053975400.1	1	Reactome: R-HSA-70895	"Branched-chain amino acid catabolism"
XP_053979132.1	7	MetaCyc: PWY-6471;Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;MetaCyc: PWY-5265;MetaCyc: PWY-6385	"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis III (mycobacteria)"
XP_053984255.1	2	Reactome: R-HSA-445355;Reactome: R-HSA-390522	"Smooth Muscle Contraction";"Striated Muscle Contraction"
XP_053988116.1	10	Reactome: R-HSA-6798695;Reactome: R-HSA-201688;Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756;Reactome: R-HSA-8939243;Reactome: R-HSA-8934903	"Neutrophil degranulation";"WNT mediated activation of DVL";"Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Receptor Mediated Mitophagy"
XP_053988960.1	1	Reactome: R-HSA-159236	"Transport of Mature mRNA derived from an Intron-Containing Transcript"
XP_053981407.1	3	Reactome: R-HSA-8964058;Reactome: R-HSA-9029569;Reactome: R-HSA-1369062	"HDL remodeling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis"
XP_053984133.1	1	Reactome: R-HSA-6782315	"tRNA modification in the nucleus and cytosol"
XP_053983891.1	3	Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440	"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network"
XP_053975444.1	1	Reactome: R-HSA-1369062	"ABC transporters in lipid homeostasis"
XP_053992433.1	10	MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;KEGG: 00680+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-7385;KEGG: 00010+4.1.2.13	"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Fructose and mannose metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis"
XP_053993280.1	1	Reactome: R-HSA-1660499	"Synthesis of PIPs at the plasma membrane"
XP_053994462.1	3	KEGG: 00520+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00051+1.1.1.271	"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"Fructose and mannose metabolism"
XP_053989952.1	5	Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-5668599	"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases"
XP_053993087.1	1	Reactome: R-HSA-5663220	"RHO GTPases Activate Formins"
XP_053987218.1	2	Reactome: R-HSA-379726;KEGG: 00970+6.1.1.4	"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"
XP_053993618.1	3	KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16	"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway"
XP_053986224.1	12	MetaCyc: PWY-5855;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5871;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-6708;MetaCyc: PWY-5856;MetaCyc: PWY-5873;MetaCyc: PWY-7233;MetaCyc: PWY-7230;MetaCyc: PWY-5872;MetaCyc: PWY-5870	"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)"
XP_053980133.1	5	Reactome: R-HSA-1445148;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intraflagellar transport";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053985703.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-983189	"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins"
XP_053979509.1	14	Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-426486;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-203927	"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"Small interfering RNA (siRNA) biogenesis";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis"
XP_053990352.1	2	Reactome: R-HSA-6807878;Reactome: R-HSA-6811434	"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic"
XP_053989665.1	1	Reactome: R-HSA-204005	"COPII-mediated vesicle transport"
XP_053980255.1	4	Reactome: R-HSA-6798695;Reactome: R-HSA-2162123;Reactome: R-HSA-499943;KEGG: 00590+5.3.99.3	"Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Arachidonic acid metabolism"
XP_053971781.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053985624.1	57	Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-180534;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-5689603;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-68827;Reactome: R-HSA-349425;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-5607761;Reactome: R-HSA-68949;Reactome: R-HSA-174113;Reactome: R-HSA-5689880;Reactome: R-HSA-8941858;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-69481;Reactome: R-HSA-8939902;Reactome: R-HSA-5668541;Reactome: R-HSA-5358346;Reactome: R-HSA-350562;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-5610783;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-8939236;Reactome: R-HSA-5658442;Reactome: R-HSA-5610780;Reactome: R-HSA-983168	"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Vpu mediated degradation of CD4";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"UCH proteinases";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of the E3 ubiquitin ligase COP1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Orc1 removal from chromatin";"SCF-beta-TrCP mediated degradation of Emi1";"Ub-specific processing proteases";"Regulation of RUNX3 expression and activity";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"G2/M Checkpoints";"Regulation of RUNX2 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog ligand biogenesis";"Regulation of ornithine decarboxylase (ODC)";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Degradation of GLI2 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RAS by GAPs";"Degradation of GLI1 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053976586.1	1	Reactome: R-HSA-194840	"Rho GTPase cycle"
XP_053978291.1	5	Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-77595	"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs"
XP_053994429.1	26	Reactome: R-HSA-6807878;Reactome: R-HSA-389977;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-190840;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-389960;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-983189;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833	"COPI-mediated anterograde transport";"Post-chaperonin tubulin folding pathway";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Kinesins";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"HCMV Early Events";"Cilium Assembly"
XP_053988278.1	2	Reactome: R-HSA-380270;Reactome: R-HSA-380320	"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes"
XP_053970953.1	1	Reactome: R-HSA-429958	"mRNA decay by 3' to 5' exoribonuclease"
XP_053993301.1	6	Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389957	"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053986002.1	3	Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676	"Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle"
XP_053984111.1	11	Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554	"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)"
XP_053986325.1	2	Reactome: R-HSA-3299685;MetaCyc: PWY-6854	"Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)"
XP_053986248.1	1	Reactome: R-HSA-6794361	"Neurexins and neuroligins"
XP_053989578.1	1	Reactome: R-HSA-6807505	"RNA polymerase II transcribes snRNA genes"
XP_053992411.1	2	Reactome: R-HSA-6803205;Reactome: R-HSA-8873719	"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation"
XP_053990690.1	3	Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436	"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway"
XP_053993706.1	7	Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-8950505;Reactome: R-HSA-389957	"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Prefoldin mediated transfer of substrate to CCT/TriC"
XP_053975013.1	1	Reactome: R-HSA-383280	"Nuclear Receptor transcription pathway"
XP_053975046.1	2	Reactome: R-HSA-418457;Reactome: R-HSA-1296052	"cGMP effects";"Ca2+ activated K+ channels"
XP_053980464.1	1	Reactome: R-HSA-8963889	"Assembly of active LPL and LIPC lipase complexes"
XP_053977605.1	13	KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7226	"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis I"
XP_053974575.1	1	Reactome: R-HSA-2514859	"Inactivation, recovery and regulation of the phototransduction cascade"
XP_053970461.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053971386.1	3	Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2;MetaCyc: PWY-7894	"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism";"Procollagen hydroxylation and glycosylation"
XP_053984464.1	1	Reactome: R-HSA-5576886	"Phase 4 - resting membrane potential"
XP_053970575.1	6	Reactome: R-HSA-9640463;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884	"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I"
XP_053984354.1	2	Reactome: R-HSA-390522;Reactome: R-HSA-445355	"Striated Muscle Contraction";"Smooth Muscle Contraction"
XP_053981937.1	1	Reactome: R-HSA-983168	"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053986173.1	16	Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702	"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition"
XP_053976927.1	5	Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610787;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780	"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'off' state";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome"
XP_053992903.1	5	Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-350054	"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway"
XP_053991318.1	18	Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-112382	"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of RNA Pol II elongation complex"
XP_053980111.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"
XP_053993537.1	1	Reactome: R-HSA-6791226	"Major pathway of rRNA processing in the nucleolus and cytosol"
XP_053986446.1	5	MetaCyc: PWY-7176;MetaCyc: PWY-7177;MetaCyc: PWY-7185;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2	"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism"
XP_053983284.1	3	Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311	"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance"
XP_053975788.1	5	Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389	"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"
XP_053985238.1	1	Reactome: R-HSA-432720	"Lysosome Vesicle Biogenesis"
XP_053978519.1	8	KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1	"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism"
XP_053973734.1	15	Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-5693565	"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"
XP_053989051.1	3	KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2	"Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism"
XP_053991015.1	1	KEGG: 04150+2.7.11.24	"mTOR signaling pathway"
XP_053991469.1	14	Reactome: R-HSA-68877;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-2173788;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-9634638;Reactome: R-HSA-3769402	"Mitotic Prometaphase";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Downregulation of TGF-beta receptor signaling";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Deactivation of the beta-catenin transactivating complex"
XP_053979054.1	4	Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-373753	"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Nephrin family interactions"
XP_053972344.1	1	Reactome: R-HSA-2299718	"Condensation of Prophase Chromosomes"
XP_053982341.1	4	Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825	"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis"
XP_053976710.1	1	KEGG: 00480+3.4.11.2	"Glutathione metabolism"
XP_053972734.1	3	Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438	"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic"
XP_053982731.1	1	Reactome: R-HSA-1296072	"Voltage gated Potassium channels"
XP_053988881.1	7	Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-6807878	"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Neutrophil degranulation";"Nephrin family interactions";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport"
XP_053983538.1	3	Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695	"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events"
XP_053991780.1	2	Reactome: R-HSA-6811434;Reactome: R-HSA-6807878	"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport"
XP_053992537.1	10	MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11	"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism"
XP_053988074.1	2	MetaCyc: PWY-7511;Reactome: R-HSA-983168	"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation"
XP_053985725.1	1	Reactome: R-HSA-189200	"Cellular hexose transport"
XP_053980565.1	1	Reactome: R-HSA-71403	"Citric acid cycle (TCA cycle)"
XP_053973344.1	5	MetaCyc: PWY-6855;MetaCyc: PWY-6906;Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514	"Chitin degradation I (archaea)";"Chitin derivatives degradation";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II"
XP_053984471.1	1	Reactome: R-HSA-8876198	"RAB GEFs exchange GTP for GDP on RABs"
XP_053986901.1	5	Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920	"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability"
XP_053981636.1	1	Reactome: R-HSA-8949664	"Processing of SMDT1"
XP_053986189.1	1	Reactome: R-HSA-6802952	"Signaling by BRAF and RAF fusions"
XP_053973197.1	1	Reactome: R-HSA-1660661	"Sphingolipid de novo biosynthesis"
XP_053978696.1	1	Reactome: R-HSA-373080	"Class B/2 (Secretin family receptors)"