Pathway_ID Pathway_Name Accession_Count Accessions KEGG: 00604+3.2.1.23 Glycosphingolipid biosynthesis - ganglio series 6 LFUL006883-PA;LFUL012258-PA;LFUL010554-PA;LFUL010553-PA;LFUL010555-PA;LFUL012024-PA Reactome: R-HSA-8853659 RET signaling 1 LFUL014130-PA KEGG: 00561+3.1.1.3 Glycerolipid metabolism 3 LFUL009402-PA;LFUL009404-PA;LFUL009398-PA Reactome: R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 5 LFUL018800-PA;LFUL009310-PA;LFUL015628-PA;LFUL014137-PA;LFUL014130-PA KEGG: 00680+5.4.2.11 Methane metabolism 1 LFUL008386-PA KEGG: 00230+3.6.1.17 Purine metabolism 1 LFUL000236-PA KEGG: 00380+2.6.1.7 Tryptophan metabolism 2 LFUL013723-PA;LFUL013724-PA MetaCyc: PWY-7663 Gondoate biosynthesis (anaerobic) 1 LFUL006083-PA Reactome: R-HSA-114508 Effects of PIP2 hydrolysis 12 LFUL006065-PA;LFUL009249-PA;LFUL006064-PA;LFUL006554-PA;LFUL000379-PA;LFUL006553-PA;LFUL009246-PA;LFUL016206-PA;LFUL019695-PA;LFUL016207-PA;LFUL015114-PA;LFUL018399-PA Reactome: R-HSA-5578999 Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) 3 LFUL008713-PA;LFUL004028-PA;LFUL019657-PA MetaCyc: PWY-5723 Rubisco shunt 5 LFUL011112-PA;LFUL005639-PA;LFUL001192-PA;LFUL012465-PA;LFUL002759-PA KEGG: 00520+2.7.7.12 Amino sugar and nucleotide sugar metabolism 1 LFUL015403-PA Reactome: R-HSA-983712 Ion channel transport 15 LFUL018924-PA;LFUL006212-PA;LFUL006476-PA;LFUL010201-PA;LFUL009771-PA;LFUL010191-PA;LFUL010662-PA;LFUL006787-PA;LFUL008406-PA;LFUL009162-PA;LFUL003394-PA;LFUL011204-PA;LFUL011205-PA;LFUL011203-PA;LFUL008957-PA KEGG: 00920+2.7.7.4 Sulfur metabolism 1 LFUL019316-PA Reactome: R-HSA-5620912 Anchoring of the basal body to the plasma membrane 23 LFUL007649-PA;LFUL015311-PA;LFUL015517-PA;LFUL001299-PA;LFUL004301-PA;LFUL005472-PA;LFUL017541-PA;LFUL002675-PA;LFUL009638-PA;LFUL010789-PA;LFUL001762-PA;LFUL011516-PA;LFUL014621-PA;LFUL009597-PA;LFUL009757-PA;LFUL016216-PA;LFUL005946-PA;LFUL018303-PA;LFUL010041-PA;LFUL001298-PA;LFUL009096-PA;LFUL003889-PA;LFUL004460-PA KEGG: 00950+1.14.16.2 Isoquinoline alkaloid biosynthesis 2 LFUL004046-PA;LFUL004047-PA MetaCyc: PWY-7165 L-ascorbate biosynthesis VI (engineered pathway) 2 LFUL004102-PA;LFUL001189-PA MetaCyc: PWY-6608 Guanosine nucleotides degradation III 5 LFUL011206-PA;LFUL011578-PA;LFUL011207-PA;LFUL011577-PA;LFUL011735-PA MetaCyc: PWY-7725 Arachidonate biosynthesis V (8-detaturase, mammals) 18 LFUL012361-PA;LFUL002423-PA;LFUL006533-PA;LFUL015420-PA;LFUL013815-PA;LFUL013814-PA;LFUL010698-PA;LFUL012359-PA;LFUL017948-PA;LFUL001095-PA;LFUL001272-PA;LFUL015422-PA;LFUL013818-PA;LFUL004766-PA;LFUL012360-PA;LFUL013817-PA;LFUL013816-PA;LFUL007078-PA KEGG: 00071+2.3.1.21 Fatty acid degradation 1 LFUL004873-PA Reactome: R-HSA-1266695 Interleukin-7 signaling 1 LFUL014130-PA KEGG: 00240+2.1.3.2 Pyrimidine metabolism 1 LFUL014037-PA Reactome: R-HSA-8939236 RUNX1 regulates transcription of genes involved in differentiation of HSCs 49 LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL015402-PA;LFUL009514-PA;LFUL002340-PA;LFUL017219-PA;LFUL017218-PA;LFUL009515-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL005608-PA;LFUL009516-PA;LFUL014805-PA;LFUL001413-PA;LFUL010468-PA;LFUL001632-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL009513-PA;LFUL006416-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL013396-PA;LFUL001667-PA;LFUL007901-PA;LFUL005657-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL009759-PA;LFUL010467-PA;LFUL013254-PA;LFUL006784-PA;LFUL010456-PA;LFUL003914-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL005128-PA KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35 Butanoate metabolism 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA MetaCyc: PWY-7586 Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation 2 LFUL006253-PA;LFUL000192-PA Reactome: R-HSA-2660826 Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant 6 LFUL004221-PA;LFUL015476-PA;LFUL009679-PA;LFUL019751-PA;LFUL009003-PA;LFUL000121-PA MetaCyc: PWY-6129 Dolichol and dolichyl phosphate biosynthesis 2 LFUL006417-PA;LFUL009957-PA KEGG: 00281+4.2.1.17 Geraniol degradation 1 LFUL017943-PA KEGG: 00561+2.3.1.20 Glycerolipid metabolism 3 LFUL002264-PA;LFUL001220-PA;LFUL000328-PA KEGG: 00380+1.14.14.1 Tryptophan metabolism 2 LFUL019543-PA;LFUL007894-PA MetaCyc: PWY-6453 Stigma estolide biosynthesis 10 LFUL011020-PA;LFUL016045-PA;LFUL016603-PA;LFUL002099-PA;LFUL017634-PA;LFUL014100-PA;LFUL005920-PA;LFUL009878-PA;LFUL008878-PA;LFUL011019-PA Reactome: R-HSA-3371453 Regulation of HSF1-mediated heat shock response 43 LFUL014137-PA;LFUL011396-PA;LFUL019322-PA;LFUL013801-PA;LFUL000978-PA;LFUL018131-PA;LFUL009840-PA;LFUL015687-PA;LFUL005156-PA;LFUL010552-PA;LFUL000977-PA;LFUL016880-PA;LFUL000200-PA;LFUL006358-PA;LFUL005157-PA;LFUL015754-PA;LFUL011549-PA;LFUL015267-PA;LFUL001450-PA;LFUL000581-PA;LFUL001437-PA;LFUL014947-PA;LFUL014325-PA;LFUL016186-PA;LFUL014078-PA;LFUL002532-PA;LFUL002666-PA;LFUL006936-PA;LFUL006282-PA;LFUL005736-PA;LFUL014080-PA;LFUL014081-PA;LFUL005565-PA;LFUL019661-PA;LFUL010864-PA;LFUL008059-PA;LFUL002533-PA;LFUL012403-PA;LFUL010119-PA;LFUL015518-PA;LFUL013881-PA;LFUL009305-PA;LFUL009303-PA KEGG: 00240+2.7.4.14 Pyrimidine metabolism 1 LFUL006106-PA MetaCyc: PWY-6483 Ceramide degradation (generic) 3 LFUL016446-PA;LFUL012328-PA;LFUL012329-PA KEGG: 00061+6.4.1.2 Fatty acid biosynthesis 1 LFUL005606-PA MetaCyc: PWY-7656 Spodoptera littoralis pheromone biosynthesis 21 LFUL012813-PA;LFUL012820-PA;LFUL012814-PA;LFUL018646-PA;LFUL002995-PA;LFUL012817-PA;LFUL012393-PA;LFUL010158-PA;LFUL013657-PA;LFUL012816-PA;LFUL018766-PA;LFUL017943-PA;LFUL012818-PA;LFUL012811-PA;LFUL008789-PA;LFUL012819-PA;LFUL018767-PA;LFUL013655-PA;LFUL013656-PA;LFUL013658-PA;LFUL010157-PA Reactome: R-HSA-433137 Sodium-coupled sulphate, di- and tri-carboxylate transporters 1 LFUL004291-PA MetaCyc: PWY-7900 Glycogen biosynthesis III (from alpha-maltose 1-phosphate) 3 LFUL014478-PA;LFUL007973-PA;LFUL014477-PA MetaCyc: PWY-7277 Sphingolipid biosynthesis (mammals) 1 LFUL009479-PA Reactome: R-HSA-5467337 APC truncation mutants have impaired AXIN binding 4 LFUL009310-PA;LFUL010552-PA;LFUL015628-PA;LFUL007844-PA Reactome: R-HSA-937042 IRAK2 mediated activation of TAK1 complex 4 LFUL004537-PA;LFUL018125-PA;LFUL005189-PA;LFUL018127-PA KEGG: 00500+3.2.1.4 Starch and sucrose metabolism 1 LFUL015102-PA Reactome: R-HSA-380095 Tachykinin receptors bind tachykinins 1 LFUL010575-PA MetaCyc: PWY-7401 Crotonate fermentation (to acetate and cyclohexane carboxylate) 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA KEGG: 00720+1.5.1.20 Carbon fixation pathways in prokaryotes 1 LFUL015994-PA KEGG: 00710+5.1.3.1 Carbon fixation in photosynthetic organisms 1 LFUL012465-PA MetaCyc: PWY-5366 Palmitoleate biosynthesis II (plants and bacteria) 1 LFUL006083-PA Reactome: R-HSA-389661 Glyoxylate metabolism and glycine degradation 19 LFUL010747-PA;LFUL005148-PA;LFUL011761-PA;LFUL004145-PA;LFUL012268-PA;LFUL008261-PA;LFUL013088-PA;LFUL006667-PA;LFUL003940-PA;LFUL001879-PA;LFUL001880-PA;LFUL006924-PA;LFUL000757-PA;LFUL018068-PA;LFUL014588-PA;LFUL018107-PA;LFUL004144-PA;LFUL003022-PA;LFUL014938-PA Reactome: R-HSA-975957 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 96 LFUL010852-PA;LFUL011000-PA;LFUL014935-PA;LFUL000563-PA;LFUL004418-PA;LFUL000565-PA;LFUL001329-PA;LFUL013995-PA;LFUL004537-PA;LFUL002673-PA;LFUL003261-PA;LFUL000695-PA;LFUL001717-PA;LFUL016822-PA;LFUL001669-PA;LFUL006688-PA;LFUL003221-PA;LFUL018450-PA;LFUL006255-PA;LFUL009485-PA;LFUL019500-PA;LFUL007167-PA;LFUL000050-PA;LFUL005935-PA;LFUL003726-PA;LFUL013851-PA;LFUL017436-PA;LFUL018996-PA;LFUL009487-PA;LFUL016060-PA;LFUL016059-PA;LFUL012852-PA;LFUL012372-PA;LFUL010697-PA;LFUL005171-PA;LFUL010275-PA;LFUL015591-PA;LFUL014785-PA;LFUL001176-PA;LFUL004636-PA;LFUL004420-PA;LFUL002950-PA;LFUL015920-PA;LFUL016069-PA;LFUL006902-PA;LFUL011563-PA;LFUL008330-PA;LFUL004637-PA;LFUL006788-PA;LFUL005594-PA;LFUL017793-PA;LFUL007358-PA;LFUL009630-PA;LFUL002148-PA;LFUL007583-PA;LFUL012702-PA;LFUL019578-PA;LFUL019054-PA;LFUL009684-PA;LFUL008016-PA;LFUL003947-PA;LFUL012271-PA;LFUL006720-PA;LFUL004974-PA;LFUL018532-PA;LFUL018953-PA;LFUL001102-PA;LFUL001681-PA;LFUL017656-PA;LFUL002208-PA;LFUL014893-PA;LFUL011278-PA;LFUL006093-PA;LFUL014225-PA;LFUL018534-PA;LFUL016786-PA;LFUL018531-PA;LFUL019701-PA;LFUL006675-PA;LFUL011123-PA;LFUL014007-PA;LFUL002249-PA;LFUL018772-PA;LFUL017285-PA;LFUL015696-PA;LFUL014304-PA;LFUL018435-PA;LFUL002925-PA;LFUL008661-PA;LFUL010862-PA;LFUL008669-PA;LFUL003725-PA;LFUL017447-PA;LFUL000564-PA;LFUL007452-PA;LFUL004596-PA KEGG: 00330+1.14.13.39 Arginine and proline metabolism 1 LFUL001456-PA Reactome: R-HSA-166166 MyD88-independent TLR4 cascade 1 LFUL014668-PA MetaCyc: PWY-6737 Starch degradation V 2 LFUL012958-PA;LFUL003990-PA MetaCyc: PWY-7285 Methylwyosine biosynthesis 4 LFUL011055-PA;LFUL002182-PA;LFUL003742-PA;LFUL011912-PA Reactome: R-HSA-167160 RNA Pol II CTD phosphorylation and interaction with CE during HIV infection 24 LFUL000254-PA;LFUL004554-PA;LFUL016324-PA;LFUL006931-PA;LFUL015513-PA;LFUL010364-PA;LFUL008825-PA;LFUL014212-PA;LFUL006150-PA;LFUL010620-PA;LFUL003284-PA;LFUL013037-PA;LFUL018856-PA;LFUL006416-PA;LFUL006932-PA;LFUL010468-PA;LFUL016326-PA;LFUL001373-PA;LFUL010456-PA;LFUL010467-PA;LFUL008827-PA;LFUL013636-PA;LFUL008550-PA;LFUL003393-PA KEGG: 00510+2.4.1.83 N-Glycan biosynthesis 1 LFUL005787-PA MetaCyc: PWY-5690 TCA cycle II (plants and fungi) 11 LFUL008263-PA;LFUL004029-PA;LFUL004113-PA;LFUL015809-PA;LFUL004114-PA;LFUL001123-PA;LFUL017635-PA;LFUL006472-PA;LFUL005914-PA;LFUL016366-PA;LFUL017636-PA KEGG: 04070+3.1.3.64 Phosphatidylinositol signaling system 1 LFUL012230-PA KEGG: 00380+3.5.1.9 Tryptophan metabolism 1 LFUL015273-PA Reactome: R-HSA-418594 G alpha (i) signalling events 21 LFUL000400-PA;LFUL012141-PA;LFUL003893-PA;LFUL010531-PA;LFUL017104-PA;LFUL010285-PA;LFUL008742-PA;LFUL008021-PA;LFUL000404-PA;LFUL016095-PA;LFUL008741-PA;LFUL008845-PA;LFUL014754-PA;LFUL000754-PA;LFUL000640-PA;LFUL000620-PA;LFUL000171-PA;LFUL004880-PA;LFUL012255-PA;LFUL014398-PA;LFUL019738-PA KEGG: 00510+2.4.1.265 N-Glycan biosynthesis 1 LFUL015953-PA Reactome: R-HSA-3134975 Regulation of innate immune responses to cytosolic DNA 1 LFUL004537-PA Reactome: R-HSA-425561 Sodium/Calcium exchangers 11 LFUL015840-PA;LFUL015839-PA;LFUL004625-PA;LFUL013584-PA;LFUL013581-PA;LFUL010819-PA;LFUL010820-PA;LFUL010300-PA;LFUL012445-PA;LFUL000706-PA;LFUL004627-PA Reactome: R-HSA-196843 Vitamin B2 (riboflavin) metabolism 4 LFUL009983-PA;LFUL005319-PA;LFUL004709-PA;LFUL001659-PA Reactome: R-HSA-6811555 PI5P Regulates TP53 Acetylation 1 LFUL009193-PA Reactome: R-HSA-76042 RNA Polymerase II Transcription Initiation And Promoter Clearance 35 LFUL001373-PA;LFUL005318-PA;LFUL010468-PA;LFUL008827-PA;LFUL013636-PA;LFUL003393-PA;LFUL016338-PA;LFUL004051-PA;LFUL016703-PA;LFUL013957-PA;LFUL019760-PA;LFUL018855-PA;LFUL015513-PA;LFUL008825-PA;LFUL018856-PA;LFUL010620-PA;LFUL014887-PA;LFUL006932-PA;LFUL000689-PA;LFUL008550-PA;LFUL010456-PA;LFUL010467-PA;LFUL014888-PA;LFUL006931-PA;LFUL004554-PA;LFUL017944-PA;LFUL006416-PA;LFUL004052-PA;LFUL016337-PA;LFUL010364-PA;LFUL014212-PA;LFUL015240-PA;LFUL003284-PA;LFUL004050-PA;LFUL013037-PA Reactome: R-HSA-71064 Lysine catabolism 1 LFUL002004-PA KEGG: 00052+2.7.7.9 Galactose metabolism 1 LFUL008565-PA Reactome: R-HSA-975956 Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) 80 LFUL013851-PA;LFUL017436-PA;LFUL000050-PA;LFUL005935-PA;LFUL003221-PA;LFUL018450-PA;LFUL006255-PA;LFUL009485-PA;LFUL019500-PA;LFUL016822-PA;LFUL000695-PA;LFUL001717-PA;LFUL006688-PA;LFUL004537-PA;LFUL013995-PA;LFUL002673-PA;LFUL003261-PA;LFUL000565-PA;LFUL001329-PA;LFUL004418-PA;LFUL010852-PA;LFUL011000-PA;LFUL004637-PA;LFUL008330-PA;LFUL006788-PA;LFUL006902-PA;LFUL011563-PA;LFUL002950-PA;LFUL015920-PA;LFUL016069-PA;LFUL001176-PA;LFUL004636-PA;LFUL004420-PA;LFUL015591-PA;LFUL010275-PA;LFUL016059-PA;LFUL012372-PA;LFUL012852-PA;LFUL010697-PA;LFUL005171-PA;LFUL016060-PA;LFUL018996-PA;LFUL009487-PA;LFUL001681-PA;LFUL017656-PA;LFUL002208-PA;LFUL011278-PA;LFUL014893-PA;LFUL008016-PA;LFUL003947-PA;LFUL004974-PA;LFUL012271-PA;LFUL006720-PA;LFUL018953-PA;LFUL001102-PA;LFUL019054-PA;LFUL012702-PA;LFUL007583-PA;LFUL007358-PA;LFUL009630-PA;LFUL017793-PA;LFUL007452-PA;LFUL004596-PA;LFUL010862-PA;LFUL008669-PA;LFUL017447-PA;LFUL000564-PA;LFUL008661-PA;LFUL018772-PA;LFUL015696-PA;LFUL018435-PA;LFUL002925-PA;LFUL014304-PA;LFUL002249-PA;LFUL006675-PA;LFUL011123-PA;LFUL019701-PA;LFUL014007-PA;LFUL014225-PA;LFUL006093-PA MetaCyc: PWY-7176 UTP and CTP de novo biosynthesis 10 LFUL003026-PA;LFUL003025-PA;LFUL005981-PA;LFUL008636-PA;LFUL011295-PA;LFUL005983-PA;LFUL017852-PA;LFUL006106-PA;LFUL017739-PA;LFUL013982-PA MetaCyc: PWY-5874 Heme degradation I 1 LFUL005036-PA Reactome: R-HSA-389977 Post-chaperonin tubulin folding pathway 15 LFUL004646-PA;LFUL013555-PA;LFUL013557-PA;LFUL014799-PA;LFUL014801-PA;LFUL017836-PA;LFUL000186-PA;LFUL014793-PA;LFUL013561-PA;LFUL003377-PA;LFUL000187-PA;LFUL013560-PA;LFUL014800-PA;LFUL000188-PA;LFUL014795-PA KEGG: 00760+2.7.1.173+2.7.1.22 Nicotinate and nicotinamide metabolism 1 LFUL015755-PA Reactome: R-HSA-69481 G2/M Checkpoints 40 LFUL005128-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL003914-PA;LFUL013254-PA;LFUL006784-PA;LFUL009759-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL015255-PA;LFUL004537-PA;LFUL007901-PA;LFUL001667-PA;LFUL013396-PA;LFUL005657-PA;LFUL017243-PA;LFUL013520-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL001183-PA;LFUL010331-PA;LFUL001632-PA;LFUL001413-PA;LFUL014805-PA;LFUL005608-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL009758-PA;LFUL004900-PA KEGG: 00230+3.5.4.4 Purine metabolism 1 LFUL003389-PA Reactome: R-HSA-176409 APC/C:Cdc20 mediated degradation of mitotic proteins 11 LFUL002279-PA;LFUL011826-PA;LFUL011394-PA;LFUL001285-PA;LFUL011827-PA;LFUL006691-PA;LFUL008983-PA;LFUL004085-PA;LFUL006381-PA;LFUL000448-PA;LFUL013953-PA MetaCyc: PWY-7053 Docosahexaenoate biosynthesis I (lower eukaryotes) 2 LFUL001272-PA;LFUL010698-PA Reactome: R-HSA-6807004 Negative regulation of MET activity 4 LFUL005095-PA;LFUL004537-PA;LFUL017488-PA;LFUL013808-PA Reactome: R-HSA-4720489 Defective ALG12 causes ALG12-CDG (CDG-1g) 1 LFUL013830-PA MetaCyc: PWY-5921 Glutaminyl-trnagln biosynthesis via transamidation 1 LFUL003072-PA KEGG: 00900+2.7.4.2 Terpenoid backbone biosynthesis 1 LFUL015364-PA Reactome: R-HSA-400511 Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) 4 LFUL015737-PA;LFUL017551-PA;LFUL006145-PA;LFUL005015-PA KEGG: 00220+6.3.1.2 Arginine biosynthesis 1 LFUL012349-PA KEGG: 00051+4.2.1.47 Fructose and mannose metabolism 1 LFUL002512-PA Reactome: R-HSA-375280 Amine ligand-binding receptors 1 LFUL001446-PA MetaCyc: PWY-3821 D-galactose detoxification 4 LFUL010337-PA;LFUL010336-PA;LFUL006901-PA;LFUL004776-PA Reactome: R-HSA-2206292 MPS VII - Sly syndrome 2 LFUL012024-PA;LFUL006883-PA Reactome: R-HSA-168333 NEP/NS2 Interacts with the Cellular Export Machinery 24 LFUL010864-PA;LFUL004116-PA;LFUL000581-PA;LFUL012019-PA;LFUL000200-PA;LFUL005157-PA;LFUL006358-PA;LFUL011549-PA;LFUL005565-PA;LFUL016880-PA;LFUL013881-PA;LFUL002532-PA;LFUL009305-PA;LFUL009303-PA;LFUL002533-PA;LFUL008059-PA;LFUL016186-PA;LFUL002666-PA;LFUL005156-PA;LFUL015687-PA;LFUL006282-PA;LFUL018131-PA;LFUL009840-PA;LFUL013801-PA KEGG: 00380+3.7.1.3 Tryptophan metabolism 2 LFUL008866-PA;LFUL008867-PA Reactome: R-HSA-8949664 Processing of SMDT1 11 LFUL001829-PA;LFUL008721-PA;LFUL001828-PA;LFUL002088-PA;LFUL002365-PA;LFUL007541-PA;LFUL000699-PA;LFUL019602-PA;LFUL013401-PA;LFUL019517-PA;LFUL010326-PA KEGG: 00071+1.3.3.6 Fatty acid degradation 2 LFUL001448-PA;LFUL001447-PA Reactome: R-HSA-77289 Mitochondrial Fatty Acid Beta-Oxidation 3 LFUL014938-PA;LFUL015795-PA;LFUL010702-PA Reactome: R-HSA-2682334 EPH-Ephrin signaling 2 LFUL012274-PA;LFUL008114-PA MetaCyc: PWY-6174 Mevalonate pathway II (archaea) 2 LFUL007555-PA;LFUL008593-PA KEGG: 00450+2.7.7.4 Selenocompound metabolism 1 LFUL019316-PA KEGG: 00514+2.4.1.221 Other types of O-glycan biosynthesis 1 LFUL000252-PA MetaCyc: PWY-5104 L-isoleucine biosynthesis IV 1 LFUL019679-PA Reactome: R-HSA-5467340 AXIN missense mutants destabilize the destruction complex 4 LFUL007844-PA;LFUL015628-PA;LFUL010552-PA;LFUL009310-PA MetaCyc: PWY-6308 L-cysteine biosynthesis II (tRNA-dependent) 4 LFUL010674-PA;LFUL004630-PA;LFUL012547-PA;LFUL006393-PA KEGG: 00270+6.3.2.3 Cysteine and methionine metabolism 1 LFUL003123-PA Reactome: R-HSA-6785470 tRNA processing in the mitochondrion 4 LFUL003742-PA;LFUL006827-PA;LFUL011215-PA;LFUL005951-PA KEGG: 00520+5.4.2.8 Amino sugar and nucleotide sugar metabolism 1 LFUL000192-PA Reactome: R-HSA-418457 cGMP effects 5 LFUL016516-PA;LFUL010272-PA;LFUL007947-PA;LFUL010274-PA;LFUL014374-PA MetaCyc: PWY-7466 Acetone degradation III (to propane-1,2-diol) 2 LFUL019543-PA;LFUL007894-PA MetaCyc: PWY-7942 5-oxo-L-proline metabolism 5 LFUL013079-PA;LFUL011898-PA;LFUL007632-PA;LFUL012272-PA;LFUL011897-PA MetaCyc: PWY-5084 2-oxoglutarate decarboxylation to succinyl-CoA 5 LFUL006666-PA;LFUL003936-PA;LFUL006667-PA;LFUL003940-PA;LFUL003935-PA MetaCyc: PWY-1861 Formaldehyde assimilation II (assimilatory RuMP Cycle) 6 LFUL011355-PA;LFUL005639-PA;LFUL012465-PA;LFUL011354-PA;LFUL002759-PA;LFUL011512-PA KEGG: 04070+2.7.1.158 Phosphatidylinositol signaling system 2 LFUL014713-PA;LFUL019642-PA MetaCyc: PWY-5028 L-histidine degradation II 1 LFUL004916-PA Reactome: R-HSA-1362409 Mitochondrial iron-sulfur cluster biogenesis 9 LFUL008950-PA;LFUL012594-PA;LFUL016787-PA;LFUL007911-PA;LFUL004606-PA;LFUL016505-PA;LFUL007210-PA;LFUL008951-PA;LFUL003519-PA Reactome: R-HSA-5626978 TNFR1-mediated ceramide production 1 LFUL007500-PA Reactome: R-HSA-174411 Polymerase switching on the C-strand of the telomere 15 LFUL002760-PA;LFUL003903-PA;LFUL007960-PA;LFUL014494-PA;LFUL011672-PA;LFUL005720-PA;LFUL009032-PA;LFUL011668-PA;LFUL013345-PA;LFUL011669-PA;LFUL008688-PA;LFUL007804-PA;LFUL006665-PA;LFUL002178-PA;LFUL001174-PA Reactome: R-HSA-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 1 LFUL013218-PA Reactome: R-HSA-9022692 Regulation of MECP2 expression and activity 16 LFUL006660-PA;LFUL009909-PA;LFUL002885-PA;LFUL009903-PA;LFUL005454-PA;LFUL019805-PA;LFUL019785-PA;LFUL008336-PA;LFUL009777-PA;LFUL009902-PA;LFUL006745-PA;LFUL009908-PA;LFUL009904-PA;LFUL015531-PA;LFUL015532-PA;LFUL004232-PA Reactome: R-HSA-381676 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 8 LFUL015154-PA;LFUL000620-PA;LFUL017104-PA;LFUL009246-PA;LFUL003893-PA;LFUL012255-PA;LFUL000640-PA;LFUL009249-PA Reactome: R-HSA-380270 Recruitment of mitotic centrosome proteins and complexes 25 LFUL010290-PA;LFUL003889-PA;LFUL009096-PA;LFUL010041-PA;LFUL018303-PA;LFUL004460-PA;LFUL014621-PA;LFUL009757-PA;LFUL006471-PA;LFUL004344-PA;LFUL012256-PA;LFUL001762-PA;LFUL011516-PA;LFUL010789-PA;LFUL009638-PA;LFUL012510-PA;LFUL004301-PA;LFUL015517-PA;LFUL015876-PA;LFUL007649-PA;LFUL015311-PA;LFUL002675-PA;LFUL017541-PA;LFUL012132-PA;LFUL010291-PA Reactome: R-HSA-373752 Netrin-1 signaling 2 LFUL016977-PA;LFUL001403-PA Reactome: R-HSA-1369007 Mitochondrial ABC transporters 1 LFUL019677-PA MetaCyc: PWY-5129 Sphingolipid biosynthesis (plants) 2 LFUL016336-PA;LFUL014857-PA MetaCyc: PWY-3961 Phosphopantothenate biosynthesis II 2 LFUL012867-PA;LFUL016820-PA MetaCyc: PWY-7921 Protein O-mannosylation I (yeast) 8 LFUL005787-PA;LFUL003052-PA;LFUL007240-PA;LFUL002764-PA;LFUL003866-PA;LFUL003867-PA;LFUL009334-PA;LFUL003439-PA Reactome: R-HSA-73776 RNA Polymerase II Promoter Escape 35 LFUL008550-PA;LFUL000689-PA;LFUL010467-PA;LFUL014888-PA;LFUL010456-PA;LFUL014887-PA;LFUL006932-PA;LFUL004052-PA;LFUL016337-PA;LFUL006416-PA;LFUL003284-PA;LFUL004050-PA;LFUL013037-PA;LFUL015240-PA;LFUL014212-PA;LFUL010364-PA;LFUL006931-PA;LFUL017944-PA;LFUL004554-PA;LFUL003393-PA;LFUL008827-PA;LFUL013636-PA;LFUL016338-PA;LFUL005318-PA;LFUL001373-PA;LFUL010468-PA;LFUL019760-PA;LFUL018855-PA;LFUL010620-PA;LFUL018856-PA;LFUL015513-PA;LFUL008825-PA;LFUL013957-PA;LFUL016703-PA;LFUL004051-PA KEGG: 00510+3.6.1.43 N-Glycan biosynthesis 1 LFUL011884-PA MetaCyc: PWY-7546 Diphthamide biosynthesis II (eukaryotes) 4 LFUL000574-PA;LFUL014729-PA;LFUL015679-PA;LFUL015678-PA KEGG: 00590+1.14.14.1 Arachidonic acid metabolism 2 LFUL019543-PA;LFUL007894-PA Reactome: R-HSA-6799198 Complex I biogenesis 40 LFUL008865-PA;LFUL009318-PA;LFUL014938-PA;LFUL009677-PA;LFUL008249-PA;LFUL012650-PA;LFUL013541-PA;LFUL017726-PA;LFUL013496-PA;LFUL008459-PA;LFUL001525-PA;LFUL001009-PA;LFUL002690-PA;LFUL017527-PA;LFUL006179-PA;LFUL017526-PA;LFUL009243-PA;LFUL005596-PA;LFUL013539-PA;LFUL016410-PA;LFUL015837-PA;LFUL003448-PA;LFUL002526-PA;LFUL002014-PA;LFUL005932-PA;LFUL000213-PA;LFUL005172-PA;LFUL011296-PA;LFUL008168-PA;LFUL016323-PA;LFUL008184-PA;LFUL007720-PA;LFUL006872-PA;LFUL015048-PA;LFUL004382-PA;LFUL004491-PA;LFUL004490-PA;LFUL000692-PA;LFUL015629-PA;LFUL001978-PA MetaCyc: PWY-7185 UTP and CTP dephosphorylation I 6 LFUL003025-PA;LFUL011206-PA;LFUL003026-PA;LFUL011207-PA;LFUL005425-PA;LFUL002917-PA MetaCyc: PWY-7400 L-arginine biosynthesis IV (archaebacteria) 4 LFUL014041-PA;LFUL014039-PA;LFUL014040-PA;LFUL014042-PA Reactome: R-HSA-5221030 TET1,2,3 and TDG demethylate DNA 2 LFUL014854-PA;LFUL012299-PA Reactome: R-HSA-1475029 Reversible hydration of carbon dioxide 4 LFUL010584-PA;LFUL012803-PA;LFUL017492-PA;LFUL012802-PA Reactome: R-HSA-4717374 Defective DPM1 causes DPM1-CDG (CDG-1e) 2 LFUL007324-PA;LFUL005787-PA Reactome: R-HSA-111457 Release of apoptotic factors from the mitochondria 2 LFUL002198-PA;LFUL007046-PA Reactome: R-HSA-2565942 Regulation of PLK1 Activity at G2/M Transition 21 LFUL015886-PA;LFUL009757-PA;LFUL014621-PA;LFUL004460-PA;LFUL010041-PA;LFUL018303-PA;LFUL003889-PA;LFUL016470-PA;LFUL009096-PA;LFUL019705-PA;LFUL002675-PA;LFUL017541-PA;LFUL007649-PA;LFUL015311-PA;LFUL004301-PA;LFUL015517-PA;LFUL004537-PA;LFUL001762-PA;LFUL011516-PA;LFUL009638-PA;LFUL010789-PA Reactome: R-HSA-4755609 Defective DHDDS causes retinitis pigmentosa 59 1 LFUL013534-PA KEGG: 00983+2.4.2.10 Drug metabolism - other enzymes 1 LFUL006717-PA Reactome: R-HSA-2160916 Hyaluronan uptake and degradation 9 LFUL003458-PA;LFUL003459-PA;LFUL001685-PA;LFUL006883-PA;LFUL007928-PA;LFUL003457-PA;LFUL012024-PA;LFUL003460-PA;LFUL005521-PA Reactome: R-HSA-165181 Inhibition of TSC complex formation by PKB 3 LFUL012151-PA;LFUL004580-PA;LFUL004581-PA Reactome: R-HSA-3000170 Syndecan interactions 2 LFUL005814-PA;LFUL003428-PA KEGG: 00230+3.5.4.10+2.1.2.3 Purine metabolism 2 LFUL015685-PA;LFUL015684-PA KEGG: 00250+3.5.1.1 Alanine, aspartate and glutamate metabolism 1 LFUL004768-PA MetaCyc: PWY-5973 Cis-vaccenate biosynthesis 1 LFUL006083-PA Reactome: R-HSA-8866907 Activation of the TFAP2 (AP-2) family of transcription factors 5 LFUL008074-PA;LFUL003362-PA;LFUL003363-PA;LFUL003361-PA;LFUL008073-PA Reactome: R-HSA-5083629 Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2 5 LFUL004915-PA;LFUL004914-PA;LFUL003866-PA;LFUL003867-PA;LFUL009334-PA Reactome: R-HSA-5632684 Hedgehog 'on' state 45 LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL014805-PA;LFUL005608-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL008156-PA;LFUL001413-PA;LFUL005059-PA;LFUL001632-PA;LFUL017243-PA;LFUL016392-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL005657-PA;LFUL013396-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL016449-PA;LFUL003914-PA;LFUL009759-PA;LFUL005058-PA;LFUL013254-PA;LFUL006784-PA;LFUL005128-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA KEGG: 00480+1.1.1.42 Glutathione metabolism 2 LFUL012684-PA;LFUL006558-PA Reactome: R-HSA-68689 CDC6 association with the ORC:origin complex 6 LFUL002734-PA;LFUL015871-PA;LFUL012084-PA;LFUL012083-PA;LFUL012409-PA;LFUL014903-PA Reactome: R-HSA-4085377 SUMOylation of SUMOylation proteins 22 LFUL002666-PA;LFUL015687-PA;LFUL006282-PA;LFUL005156-PA;LFUL013801-PA;LFUL018131-PA;LFUL009840-PA;LFUL000581-PA;LFUL010864-PA;LFUL016880-PA;LFUL005565-PA;LFUL000200-PA;LFUL005157-PA;LFUL006358-PA;LFUL011549-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL002533-PA;LFUL008059-PA;LFUL016186-PA Reactome: R-HSA-8854518 AURKA Activation by TPX2 19 LFUL015517-PA;LFUL004301-PA;LFUL007649-PA;LFUL015311-PA;LFUL017541-PA;LFUL002675-PA;LFUL009638-PA;LFUL010789-PA;LFUL011516-PA;LFUL001762-PA;LFUL009882-PA;LFUL009757-PA;LFUL014621-PA;LFUL005521-PA;LFUL003889-PA;LFUL009096-PA;LFUL018303-PA;LFUL010041-PA;LFUL004460-PA Reactome: R-HSA-110357 Displacement of DNA glycosylase by APEX1 8 LFUL017500-PA;LFUL008002-PA;LFUL004339-PA;LFUL014324-PA;LFUL014854-PA;LFUL013973-PA;LFUL004576-PA;LFUL016664-PA Reactome: R-HSA-9617324 Negative regulation of NMDA receptor-mediated neuronal transmission 4 LFUL010848-PA;LFUL018841-PA;LFUL010847-PA;LFUL002885-PA KEGG: 00480+1.11.1.15 Glutathione metabolism 8 LFUL010428-PA;LFUL017725-PA;LFUL019187-PA;LFUL011882-PA;LFUL005665-PA;LFUL001915-PA;LFUL007825-PA;LFUL006005-PA Reactome: R-HSA-5357956 TNFR1-induced NFkappaB signaling pathway 8 LFUL012769-PA;LFUL018125-PA;LFUL005189-PA;LFUL012768-PA;LFUL004537-PA;LFUL013163-PA;LFUL018127-PA;LFUL010280-PA MetaCyc: PWY-7187 Pyrimidine deoxyribonucleotides de novo biosynthesis II 12 LFUL017852-PA;LFUL005983-PA;LFUL013982-PA;LFUL017739-PA;LFUL011295-PA;LFUL008636-PA;LFUL000002-PA;LFUL002258-PA;LFUL003582-PA;LFUL005981-PA;LFUL002259-PA;LFUL014206-PA KEGG: 00591+1.14.14.1 Linoleic acid metabolism 2 LFUL007894-PA;LFUL019543-PA Reactome: R-HSA-937041 IKK complex recruitment mediated by RIP1 3 LFUL014668-PA;LFUL010280-PA;LFUL004537-PA Reactome: R-HSA-170670 Adenylate cyclase inhibitory pathway 6 LFUL000754-PA;LFUL004880-PA;LFUL008742-PA;LFUL010531-PA;LFUL008741-PA;LFUL014754-PA KEGG: 00010+5.3.1.1 Glycolysis / Gluconeogenesis 1 LFUL005591-PA KEGG: 00930+4.2.1.17 Caprolactam degradation 1 LFUL017943-PA Reactome: R-HSA-2468052 Establishment of Sister Chromatid Cohesion 6 LFUL000175-PA;LFUL001864-PA;LFUL001103-PA;LFUL008627-PA;LFUL012129-PA;LFUL006602-PA Reactome: R-HSA-5173214 O-glycosylation of TSR domain-containing proteins 26 LFUL010351-PA;LFUL006829-PA;LFUL005672-PA;LFUL006832-PA;LFUL016899-PA;LFUL006833-PA;LFUL005249-PA;LFUL008472-PA;LFUL006830-PA;LFUL005671-PA;LFUL014661-PA;LFUL015588-PA;LFUL004425-PA;LFUL011650-PA;LFUL013848-PA;LFUL008146-PA;LFUL011651-PA;LFUL005250-PA;LFUL008065-PA;LFUL000325-PA;LFUL014662-PA;LFUL008471-PA;LFUL008066-PA;LFUL000153-PA;LFUL005670-PA;LFUL000326-PA KEGG: 00515+2.7.1.183 Mannose type O-glycan biosynthesis 1 LFUL017446-PA MetaCyc: PWY-5870 Ubiquinol-8 biosynthesis (eukaryotic) 4 LFUL000814-PA;LFUL017908-PA;LFUL017907-PA;LFUL002067-PA Reactome: R-HSA-168325 Viral Messenger RNA Synthesis 33 LFUL008825-PA;LFUL002532-PA;LFUL010620-PA;LFUL018856-PA;LFUL016186-PA;LFUL000581-PA;LFUL016880-PA;LFUL000200-PA;LFUL005157-PA;LFUL006358-PA;LFUL011549-PA;LFUL015687-PA;LFUL005156-PA;LFUL013801-PA;LFUL008827-PA;LFUL018131-PA;LFUL009840-PA;LFUL001373-PA;LFUL010364-PA;LFUL009305-PA;LFUL013881-PA;LFUL003284-PA;LFUL013037-PA;LFUL009303-PA;LFUL002533-PA;LFUL008059-PA;LFUL010864-PA;LFUL006931-PA;LFUL005565-PA;LFUL006282-PA;LFUL008550-PA;LFUL006932-PA;LFUL002666-PA Reactome: R-HSA-5654693 FRS-mediated FGFR1 signaling 1 LFUL006796-PA Reactome: R-HSA-174403 Glutathione synthesis and recycling 10 LFUL007701-PA;LFUL012272-PA;LFUL008713-PA;LFUL003123-PA;LFUL004028-PA;LFUL011543-PA;LFUL019657-PA;LFUL007702-PA;LFUL011898-PA;LFUL011897-PA Reactome: R-HSA-1660662 Glycosphingolipid metabolism 22 LFUL012329-PA;LFUL015350-PA;LFUL001653-PA;LFUL003457-PA;LFUL008412-PA;LFUL015348-PA;LFUL007500-PA;LFUL005717-PA;LFUL008313-PA;LFUL003458-PA;LFUL002937-PA;LFUL002276-PA;LFUL008414-PA;LFUL010970-PA;LFUL007147-PA;LFUL007928-PA;LFUL012328-PA;LFUL003460-PA;LFUL009479-PA;LFUL003459-PA;LFUL001685-PA;LFUL014857-PA KEGG: 00960+2.6.1.1 Tropane, piperidine and pyridine alkaloid biosynthesis 2 LFUL003406-PA;LFUL011379-PA MetaCyc: PWY-381 Nitrate reduction II (assimilatory) 1 LFUL012349-PA KEGG: 00190+7.1.1.8 Oxidative phosphorylation 1 LFUL009172-PA Reactome: R-HSA-196025 Formation of annular gap junctions 2 LFUL007853-PA;LFUL003059-PA MetaCyc: PWY-7158 L-phenylalanine degradation V 2 LFUL004045-PA;LFUL000107-PA Reactome: R-HSA-8963889 Assembly of active LPL and LIPC lipase complexes 2 LFUL002083-PA;LFUL007808-PA Reactome: R-HSA-5696397 Gap-filling DNA repair synthesis and ligation in GG-NER 18 LFUL009325-PA;LFUL007277-PA;LFUL019536-PA;LFUL007279-PA;LFUL014494-PA;LFUL002760-PA;LFUL006665-PA;LFUL008688-PA;LFUL013345-PA;LFUL011669-PA;LFUL011672-PA;LFUL005720-PA;LFUL004537-PA;LFUL007960-PA;LFUL003903-PA;LFUL001437-PA;LFUL011668-PA;LFUL005736-PA Reactome: R-HSA-191273 Cholesterol biosynthesis 5 LFUL011043-PA;LFUL008593-PA;LFUL007555-PA;LFUL015364-PA;LFUL019357-PA KEGG: 00561+2.7.1.107 Glycerolipid metabolism 9 LFUL016207-PA;LFUL015114-PA;LFUL019695-PA;LFUL016206-PA;LFUL006554-PA;LFUL006553-PA;LFUL006064-PA;LFUL000379-PA;LFUL006065-PA MetaCyc: PWY-6610 Adenine salvage 1 LFUL004695-PA Reactome: R-HSA-427589 Type II Na+/Pi cotransporters 1 LFUL017667-PA Reactome: R-HSA-9635644 Inhibition of membrane repair 1 LFUL013808-PA MetaCyc: PWY-6019 Pseudouridine degradation 1 LFUL015553-PA Reactome: R-HSA-418359 Reduction of cytosolic Ca++ levels 7 LFUL006995-PA;LFUL006994-PA;LFUL004627-PA;LFUL013584-PA;LFUL013581-PA;LFUL009789-PA;LFUL006996-PA MetaCyc: PWY-7117 C4 photosynthetic carbon assimilation cycle, PEPCK type 7 LFUL012802-PA;LFUL017492-PA;LFUL011379-PA;LFUL003406-PA;LFUL010584-PA;LFUL012803-PA;LFUL004391-PA Reactome: R-HSA-192456 Digestion of dietary lipid 3 LFUL009402-PA;LFUL009398-PA;LFUL009404-PA Reactome: R-HSA-3769402 Deactivation of the beta-catenin transactivating complex 11 LFUL005993-PA;LFUL004116-PA;LFUL015174-PA;LFUL002553-PA;LFUL008435-PA;LFUL000579-PA;LFUL011069-PA;LFUL010269-PA;LFUL007844-PA;LFUL004537-PA;LFUL010270-PA MetaCyc: PWY-8086 (S)-lactate fermentation to propanoate, acetate and hydrogen 6 LFUL015809-PA;LFUL017636-PA;LFUL004113-PA;LFUL017635-PA;LFUL004114-PA;LFUL015394-PA Reactome: R-HSA-8943724 Regulation of PTEN gene transcription 23 LFUL010410-PA;LFUL001476-PA;LFUL012362-PA;LFUL016180-PA;LFUL016716-PA;LFUL011021-PA;LFUL009328-PA;LFUL009057-PA;LFUL004570-PA;LFUL004849-PA;LFUL002061-PA;LFUL010339-PA;LFUL001193-PA;LFUL001475-PA;LFUL014905-PA;LFUL014137-PA;LFUL009573-PA;LFUL012765-PA;LFUL002108-PA;LFUL006345-PA;LFUL007465-PA;LFUL004571-PA;LFUL006140-PA KEGG: 00564+2.3.1.15 Glycerophospholipid metabolism 2 LFUL014100-PA;LFUL016603-PA KEGG: 00920+2.7.1.25 Sulfur metabolism 1 LFUL014566-PA Reactome: R-HSA-191859 snRNP Assembly 37 LFUL006282-PA;LFUL009206-PA;LFUL000483-PA;LFUL016599-PA;LFUL002666-PA;LFUL000565-PA;LFUL009303-PA;LFUL013881-PA;LFUL009305-PA;LFUL008059-PA;LFUL002533-PA;LFUL010864-PA;LFUL012952-PA;LFUL005565-PA;LFUL015835-PA;LFUL015687-PA;LFUL000564-PA;LFUL005156-PA;LFUL013801-PA;LFUL009060-PA;LFUL009840-PA;LFUL018131-PA;LFUL015342-PA;LFUL012599-PA;LFUL002532-PA;LFUL016186-PA;LFUL013089-PA;LFUL013519-PA;LFUL000581-PA;LFUL017230-PA;LFUL007830-PA;LFUL016290-PA;LFUL016880-PA;LFUL011549-PA;LFUL006358-PA;LFUL000200-PA;LFUL005157-PA MetaCyc: PWY-7220 Adenosine deoxyribonucleotides de novo biosynthesis II 26 LFUL008636-PA;LFUL013982-PA;LFUL004400-PA;LFUL018976-PA;LFUL016612-PA;LFUL013124-PA;LFUL017179-PA;LFUL001680-PA;LFUL008100-PA;LFUL019301-PA;LFUL004087-PA;LFUL005981-PA;LFUL013859-PA;LFUL008033-PA;LFUL015842-PA;LFUL005848-PA;LFUL011295-PA;LFUL017739-PA;LFUL003861-PA;LFUL006960-PA;LFUL017852-PA;LFUL019261-PA;LFUL005983-PA;LFUL014063-PA;LFUL019252-PA;LFUL014941-PA Reactome: R-HSA-5620922 BBSome-mediated cargo-targeting to cilium 9 LFUL013637-PA;LFUL016392-PA;LFUL017103-PA;LFUL009343-PA;LFUL009144-PA;LFUL007016-PA;LFUL003712-PA;LFUL003684-PA;LFUL004185-PA Reactome: R-HSA-9665247 Resistance of ERBB2 KD mutants to osimertinib 1 LFUL010369-PA Reactome: R-HSA-4549356 Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 1 LFUL006200-PA MetaCyc: PWY-6383 Mono-trans, poly-cis decaprenyl phosphate biosynthesis 3 LFUL008593-PA;LFUL011744-PA;LFUL004955-PA Reactome: R-HSA-5607763 CLEC7A (Dectin-1) induces NFAT activation 2 LFUL009246-PA;LFUL009249-PA Reactome: R-HSA-5696395 Formation of Incision Complex in GG-NER 20 LFUL000317-PA;LFUL010468-PA;LFUL013636-PA;LFUL009780-PA;LFUL003393-PA;LFUL010456-PA;LFUL006135-PA;LFUL010467-PA;LFUL001333-PA;LFUL005736-PA;LFUL008596-PA;LFUL006338-PA;LFUL001437-PA;LFUL004554-PA;LFUL004061-PA;LFUL011164-PA;LFUL004537-PA;LFUL006416-PA;LFUL014212-PA;LFUL015513-PA MetaCyc: PWY-7589 Palmitoleate biosynthesis III (cyanobacteria) 5 LFUL016045-PA;LFUL008878-PA;LFUL009878-PA;LFUL002099-PA;LFUL017634-PA Reactome: R-HSA-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors 3 LFUL003361-PA;LFUL003362-PA;LFUL003363-PA MetaCyc: PWY-7887 Protein SAMPylation and SAMP-mediated thiolation 2 LFUL003909-PA;LFUL001536-PA KEGG: 00620+6.2.1.1 Pyruvate metabolism 2 LFUL006868-PA;LFUL001222-PA Reactome: R-HSA-9613354 Lipophagy 2 LFUL001585-PA;LFUL005590-PA KEGG: 00860+1.3.3.3 Porphyrin and chlorophyll metabolism 2 LFUL001554-PA;LFUL001555-PA Reactome: R-HSA-5632681 Ligand-receptor interactions 4 LFUL017925-PA;LFUL000313-PA;LFUL005058-PA;LFUL005059-PA MetaCyc: PWY-4061 Glutathione-mediated detoxification I 8 LFUL012058-PA;LFUL012059-PA;LFUL004307-PA;LFUL016403-PA;LFUL016402-PA;LFUL014136-PA;LFUL015031-PA;LFUL003732-PA Reactome: R-HSA-6802955 Paradoxical activation of RAF signaling by kinase inactive BRAF 6 LFUL001132-PA;LFUL014137-PA;LFUL015596-PA;LFUL015597-PA;LFUL011508-PA;LFUL002885-PA MetaCyc: PWY-2161B Glutamate removal from folates 1 LFUL006877-PA KEGG: 00230+2.7.6.1 Purine metabolism 3 LFUL006507-PA;LFUL006506-PA;LFUL002929-PA Reactome: R-HSA-170660 Adenylate cyclase activating pathway 6 LFUL000754-PA;LFUL004880-PA;LFUL008742-PA;LFUL010531-PA;LFUL008741-PA;LFUL014754-PA Reactome: R-HSA-6793080 rRNA modification in the mitochondrion 1 LFUL011677-PA KEGG: 00051+4.1.2.13 Fructose and mannose metabolism 1 LFUL011512-PA KEGG: 00983+3.5.4.5 Drug metabolism - other enzymes 1 LFUL011652-PA KEGG: 00020+1.2.4.1 Citrate cycle (TCA cycle) 1 LFUL010747-PA Reactome: R-HSA-196819 Vitamin B1 (thiamin) metabolism 3 LFUL006365-PA;LFUL003755-PA;LFUL009445-PA KEGG: 00480+1.1.1.49 Glutathione metabolism 1 LFUL018313-PA MetaCyc: PWY-6122 5-aminoimidazole ribonucleotide biosynthesis II 3 LFUL013571-PA;LFUL017016-PA;LFUL013568-PA MetaCyc: PWY-8072 Alanine racemization 1 LFUL007185-PA Reactome: R-HSA-5579026 Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) 2 LFUL007911-PA;LFUL003519-PA Reactome: R-HSA-5602680 MyD88 deficiency (TLR5) 1 LFUL018800-PA Reactome: R-HSA-428930 Thromboxane signalling through TP receptor 5 LFUL012255-PA;LFUL000620-PA;LFUL003893-PA;LFUL017104-PA;LFUL000640-PA KEGG: 00970+6.1.1.20 Aminoacyl-tRNA biosynthesis 6 LFUL015053-PA;LFUL013395-PA;LFUL013369-PA;LFUL002381-PA;LFUL003005-PA;LFUL002380-PA Reactome: R-HSA-3232142 SUMOylation of ubiquitinylation proteins 23 LFUL002666-PA;LFUL005156-PA;LFUL012646-PA;LFUL006282-PA;LFUL015687-PA;LFUL018131-PA;LFUL009840-PA;LFUL013801-PA;LFUL010864-PA;LFUL000581-PA;LFUL005157-PA;LFUL000200-PA;LFUL006358-PA;LFUL011549-PA;LFUL016880-PA;LFUL005565-PA;LFUL009305-PA;LFUL002532-PA;LFUL013881-PA;LFUL009303-PA;LFUL008059-PA;LFUL002533-PA;LFUL016186-PA Reactome: R-HSA-163210 Formation of ATP by chemiosmotic coupling 11 LFUL014803-PA;LFUL014557-PA;LFUL008719-PA;LFUL008428-PA;LFUL016356-PA;LFUL000166-PA;LFUL017101-PA;LFUL014223-PA;LFUL014521-PA;LFUL017269-PA;LFUL007276-PA Reactome: R-HSA-8953750 Transcriptional Regulation by E2F6 13 LFUL016074-PA;LFUL003633-PA;LFUL007465-PA;LFUL019463-PA;LFUL009750-PA;LFUL009237-PA;LFUL009289-PA;LFUL004849-PA;LFUL012191-PA;LFUL016716-PA;LFUL018372-PA;LFUL000180-PA;LFUL000101-PA Reactome: R-HSA-83936 Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 6 LFUL005020-PA;LFUL003387-PA;LFUL015579-PA;LFUL002163-PA;LFUL005032-PA;LFUL005031-PA KEGG: 00564+3.1.3.27 Glycerophospholipid metabolism 1 LFUL014211-PA KEGG: 00480+4.3.2.9 Glutathione metabolism 2 LFUL007701-PA;LFUL007702-PA KEGG: 00520+5.3.1.9 Amino sugar and nucleotide sugar metabolism 1 LFUL001099-PA Reactome: R-HSA-450321 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 4 LFUL018125-PA;LFUL004537-PA;LFUL018127-PA;LFUL005189-PA Reactome: R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA 12 LFUL006413-PA;LFUL000541-PA;LFUL005320-PA;LFUL003231-PA;LFUL015271-PA;LFUL010888-PA;LFUL015691-PA;LFUL003227-PA;LFUL013449-PA;LFUL008668-PA;LFUL011544-PA;LFUL018238-PA Reactome: R-HSA-72086 mRNA Capping 26 LFUL006416-PA;LFUL010620-PA;LFUL003284-PA;LFUL013037-PA;LFUL018856-PA;LFUL006150-PA;LFUL014212-PA;LFUL000565-PA;LFUL015513-PA;LFUL010364-PA;LFUL008825-PA;LFUL006931-PA;LFUL016324-PA;LFUL004554-PA;LFUL000254-PA;LFUL003393-PA;LFUL008550-PA;LFUL008827-PA;LFUL013636-PA;LFUL010467-PA;LFUL000564-PA;LFUL010456-PA;LFUL001373-PA;LFUL016326-PA;LFUL010468-PA;LFUL006932-PA Reactome: R-HSA-425397 Transport of vitamins, nucleosides, and related molecules 1 LFUL011999-PA Reactome: R-HSA-1169091 Activation of NF-kappaB in B cells 45 LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL009758-PA;LFUL004900-PA;LFUL013520-PA;LFUL010327-PA;LFUL018065-PA;LFUL017608-PA;LFUL010331-PA;LFUL001183-PA;LFUL001632-PA;LFUL015886-PA;LFUL001413-PA;LFUL014805-PA;LFUL010280-PA;LFUL005608-PA;LFUL018125-PA;LFUL000664-PA;LFUL016970-PA;LFUL003567-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL017243-PA;LFUL005128-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL003914-PA;LFUL016470-PA;LFUL013254-PA;LFUL006784-PA;LFUL009759-PA;LFUL018127-PA Reactome: R-HSA-180585 Vif-mediated degradation of APOBEC3G 42 LFUL017243-PA;LFUL015255-PA;LFUL005657-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL000664-PA;LFUL016970-PA;LFUL002212-PA;LFUL003567-PA;LFUL004885-PA;LFUL003914-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL005128-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL014805-PA;LFUL005608-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL010331-PA;LFUL001183-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA KEGG: 00010+2.7.1.40 Glycolysis / Gluconeogenesis 1 LFUL001192-PA KEGG: 00380+1.11.1.6 Tryptophan metabolism 2 LFUL005869-PA;LFUL019446-PA Reactome: R-HSA-109704 PI3K Cascade 1 LFUL004611-PA Reactome: R-HSA-8853884 Transcriptional Regulation by VENTX 16 LFUL006691-PA;LFUL011394-PA;LFUL004232-PA;LFUL015532-PA;LFUL015531-PA;LFUL006745-PA;LFUL004085-PA;LFUL008983-PA;LFUL011827-PA;LFUL001285-PA;LFUL011826-PA;LFUL002279-PA;LFUL005454-PA;LFUL013953-PA;LFUL000448-PA;LFUL006381-PA KEGG: 00970+6.1.1.11 Aminoacyl-tRNA biosynthesis 4 LFUL014709-PA;LFUL008058-PA;LFUL011093-PA;LFUL014710-PA Reactome: R-HSA-9013973 TICAM1-dependent activation of IRF3/IRF7 2 LFUL004537-PA;LFUL018695-PA Reactome: R-HSA-2046106 alpha-linolenic acid (ALA) metabolism 1 LFUL000576-PA KEGG: 00670+2.1.2.9 One carbon pool by folate 1 LFUL000378-PA KEGG: 00240+6.3.4.2 Pyrimidine metabolism 2 LFUL003025-PA;LFUL003026-PA KEGG: 00790+1.14.16.2 Folate biosynthesis 2 LFUL004046-PA;LFUL004047-PA KEGG: 00510+2.4.1.257+2.4.1.132 N-Glycan biosynthesis 1 LFUL013826-PA Reactome: R-HSA-2470946 Cohesin Loading onto Chromatin 11 LFUL001864-PA;LFUL002058-PA;LFUL019640-PA;LFUL019739-PA;LFUL016025-PA;LFUL008627-PA;LFUL006602-PA;LFUL006511-PA;LFUL000175-PA;LFUL001671-PA;LFUL012129-PA Reactome: R-HSA-9665246 Resistance of ERBB2 KD mutants to neratinib 1 LFUL010369-PA KEGG: 00640+6.2.1.1 Propanoate metabolism 2 LFUL006868-PA;LFUL001222-PA KEGG: 00511+3.2.1.23 Other glycan degradation 6 LFUL010554-PA;LFUL010555-PA;LFUL010553-PA;LFUL006883-PA;LFUL012258-PA;LFUL012024-PA KEGG: 00240+4.1.1.23 Pyrimidine metabolism 1 LFUL006715-PA Reactome: R-HSA-68877 Mitotic Prometaphase 51 LFUL005882-PA;LFUL004579-PA;LFUL009096-PA;LFUL002590-PA;LFUL004646-PA;LFUL015628-PA;LFUL000922-PA;LFUL010682-PA;LFUL006593-PA;LFUL002666-PA;LFUL013560-PA;LFUL007223-PA;LFUL019068-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL000365-PA;LFUL014793-PA;LFUL011743-PA;LFUL013555-PA;LFUL009310-PA;LFUL010864-PA;LFUL015769-PA;LFUL014800-PA;LFUL001537-PA;LFUL004116-PA;LFUL004301-PA;LFUL002593-PA;LFUL003377-PA;LFUL005565-PA;LFUL015687-PA;LFUL013557-PA;LFUL014799-PA;LFUL010213-PA;LFUL006582-PA;LFUL002592-PA;LFUL012256-PA;LFUL014116-PA;LFUL004963-PA;LFUL010681-PA;LFUL010020-PA;LFUL014801-PA;LFUL014795-PA;LFUL009240-PA;LFUL015753-PA;LFUL000200-PA;LFUL000435-PA;LFUL016557-PA;LFUL013561-PA;LFUL008457-PA;LFUL016880-PA Reactome: R-HSA-422356 Regulation of insulin secretion 3 LFUL009249-PA;LFUL009246-PA;LFUL013791-PA Reactome: R-HSA-388844 Receptor-type tyrosine-protein phosphatases 3 LFUL010867-PA;LFUL010868-PA;LFUL010866-PA Reactome: R-HSA-167287 HIV elongation arrest and recovery 24 LFUL001415-PA;LFUL002536-PA;LFUL016326-PA;LFUL001373-PA;LFUL008343-PA;LFUL006932-PA;LFUL008550-PA;LFUL004885-PA;LFUL008827-PA;LFUL002212-PA;LFUL006931-PA;LFUL000398-PA;LFUL008342-PA;LFUL016324-PA;LFUL014608-PA;LFUL003397-PA;LFUL003797-PA;LFUL007672-PA;LFUL010620-PA;LFUL003284-PA;LFUL018856-PA;LFUL013037-PA;LFUL008825-PA;LFUL010364-PA KEGG: 00520+2.4.1.16 Amino sugar and nucleotide sugar metabolism 4 LFUL017831-PA;LFUL017833-PA;LFUL005668-PA;LFUL017830-PA KEGG: 00562+3.1.3.56 Inositol phosphate metabolism 1 LFUL009747-PA Reactome: R-HSA-5624138 Trafficking of myristoylated proteins to the cilium 1 LFUL011295-PA Reactome: R-HSA-418217 G beta:gamma signalling through PLC beta 6 LFUL012255-PA;LFUL000620-PA;LFUL000640-PA;LFUL006196-PA;LFUL003893-PA;LFUL017104-PA MetaCyc: PWY-6906 Chitin derivatives degradation 4 LFUL009918-PA;LFUL003416-PA;LFUL003224-PA;LFUL005858-PA KEGG: 00010+6.2.1.1 Glycolysis / Gluconeogenesis 2 LFUL001222-PA;LFUL006868-PA Reactome: R-HSA-5603027 IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR) 1 LFUL010280-PA MetaCyc: PWY-6749 CMP-legionaminate biosynthesis I 5 LFUL002889-PA;LFUL002432-PA;LFUL002430-PA;LFUL012198-PA;LFUL012196-PA KEGG: 00860+1.16.3.1 Porphyrin and chlorophyll metabolism 1 LFUL007210-PA MetaCyc: PWY-7409 Phospholipid remodeling (phosphatidylethanolamine, yeast) 20 LFUL019491-PA;LFUL013309-PA;LFUL013311-PA;LFUL016033-PA;LFUL013307-PA;LFUL010843-PA;LFUL004585-PA;LFUL013308-PA;LFUL012016-PA;LFUL002720-PA;LFUL016034-PA;LFUL016035-PA;LFUL012592-PA;LFUL016031-PA;LFUL016881-PA;LFUL002721-PA;LFUL016032-PA;LFUL002722-PA;LFUL011621-PA;LFUL013310-PA MetaCyc: PWY-7416 Phospholipid remodeling (phosphatidylcholine, yeast) 20 LFUL016035-PA;LFUL016034-PA;LFUL002720-PA;LFUL013310-PA;LFUL002722-PA;LFUL011621-PA;LFUL016032-PA;LFUL016881-PA;LFUL002721-PA;LFUL016031-PA;LFUL012592-PA;LFUL013309-PA;LFUL019491-PA;LFUL012016-PA;LFUL013308-PA;LFUL004585-PA;LFUL013311-PA;LFUL016033-PA;LFUL013307-PA;LFUL010843-PA Reactome: R-HSA-418886 Netrin mediated repulsion signals 2 LFUL007771-PA;LFUL017211-PA MetaCyc: PWY-7426 Complex N-linked glycan biosynthesis (vertebrates) 3 LFUL011017-PA;LFUL018519-PA;LFUL006201-PA KEGG: 00230+3.6.1.9 Purine metabolism 2 LFUL000002-PA;LFUL014206-PA Reactome: R-HSA-1236382 Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants 2 LFUL010369-PA;LFUL004537-PA Reactome: R-HSA-6803207 TP53 Regulates Transcription of Caspase Activators and Caspases 6 LFUL008399-PA;LFUL008605-PA;LFUL003920-PA;LFUL018372-PA;LFUL006936-PA;LFUL016074-PA MetaCyc: PWY-6638 Sulfolactate degradation III 2 LFUL011379-PA;LFUL003406-PA MetaCyc: PWY-6369 Inositol diphosphates biosynthesis 4 LFUL000654-PA;LFUL000653-PA;LFUL019642-PA;LFUL014713-PA Reactome: R-HSA-170968 Frs2-mediated activation 1 LFUL014137-PA Reactome: R-HSA-5576890 Phase 3 - rapid repolarisation 1 LFUL006730-PA Reactome: R-HSA-8939246 RUNX1 regulates transcription of genes involved in differentiation of myeloid cells 4 LFUL009513-PA;LFUL009515-PA;LFUL009514-PA;LFUL009516-PA Reactome: R-HSA-427359 SIRT1 negatively regulates rRNA expression 3 LFUL011953-PA;LFUL008061-PA;LFUL011954-PA MetaCyc: PWY-7765 3-hydroxy-4-methyl-anthranilate biosynthesis II 1 LFUL015273-PA MetaCyc: PWY-7233 Ubiquinol-6 bypass biosynthesis (eukaryotic) 2 LFUL002067-PA;LFUL000814-PA KEGG: 00410+1.3.3.6 beta-Alanine metabolism 2 LFUL001447-PA;LFUL001448-PA MetaCyc: PWY-6886 1-butanol autotrophic biosynthesis (engineered) 3 LFUL008549-PA;LFUL001192-PA;LFUL011112-PA Reactome: R-HSA-5607761 Dectin-1 mediated noncanonical NF-kB signaling 44 LFUL016470-PA;LFUL003914-PA;LFUL001478-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL005128-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL017243-PA;LFUL004537-PA;LFUL007901-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL015255-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL002709-PA;LFUL014805-PA;LFUL005608-PA;LFUL010331-PA;LFUL001183-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL013520-PA;LFUL001413-PA;LFUL015886-PA;LFUL001632-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA MetaCyc: PWY-6352 3-phosphoinositide biosynthesis 5 LFUL017404-PA;LFUL004611-PA;LFUL018428-PA;LFUL002586-PA;LFUL018426-PA Reactome: R-HSA-8851708 Signaling by FGFR2 IIIa TM 13 LFUL008825-PA;LFUL010364-PA;LFUL000565-PA;LFUL000564-PA;LFUL018856-PA;LFUL003284-PA;LFUL013037-PA;LFUL010620-PA;LFUL008827-PA;LFUL008550-PA;LFUL006932-PA;LFUL006931-PA;LFUL001373-PA KEGG: 00360+4.2.1.17 Phenylalanine metabolism 3 LFUL018646-PA;LFUL017943-PA;LFUL012393-PA MetaCyc: PWY-8049 Pederin biosynthesis 1 LFUL006083-PA Reactome: R-HSA-3371571 HSF1-dependent transactivation 8 LFUL002885-PA;LFUL004571-PA;LFUL006140-PA;LFUL010339-PA;LFUL004570-PA;LFUL006443-PA;LFUL001476-PA;LFUL001475-PA MetaCyc: PWY-7115 C4 photosynthetic carbon assimilation cycle, NAD-ME type 10 LFUL015809-PA;LFUL004113-PA;LFUL011379-PA;LFUL010584-PA;LFUL004391-PA;LFUL012802-PA;LFUL017492-PA;LFUL004114-PA;LFUL003406-PA;LFUL012803-PA Reactome: R-HSA-9608290 Defective MUTYH substrate processing 1 LFUL014324-PA Reactome: R-HSA-8876493 InlA-mediated entry of Listeria monocytogenes into host cells 1 LFUL004537-PA MetaCyc: PWY-7445 Luteolin triglucuronide degradation 7 LFUL019366-PA;LFUL004976-PA;LFUL010195-PA;LFUL006897-PA;LFUL006904-PA;LFUL010193-PA;LFUL010194-PA KEGG: 04714+2.7.11.1 Thermogenesis 50 LFUL018447-PA;LFUL002766-PA;LFUL000251-PA;LFUL016885-PA;LFUL018448-PA;LFUL001476-PA;LFUL004673-PA;LFUL013749-PA;LFUL000247-PA;LFUL008438-PA;LFUL006034-PA;LFUL010552-PA;LFUL000550-PA;LFUL004423-PA;LFUL010551-PA;LFUL013361-PA;LFUL017285-PA;LFUL000058-PA;LFUL016077-PA;LFUL012699-PA;LFUL004296-PA;LFUL001475-PA;LFUL009466-PA;LFUL000059-PA;LFUL016685-PA;LFUL000924-PA;LFUL015097-PA;LFUL006336-PA;LFUL006176-PA;LFUL000250-PA;LFUL001467-PA;LFUL003791-PA;LFUL015598-PA;LFUL019451-PA;LFUL000248-PA;LFUL015336-PA;LFUL003065-PA;LFUL010118-PA;LFUL012191-PA;LFUL014180-PA;LFUL008160-PA;LFUL001132-PA;LFUL015132-PA;LFUL006936-PA;LFUL014459-PA;LFUL000249-PA;LFUL014316-PA;LFUL003125-PA;LFUL005999-PA;LFUL000595-PA Reactome: R-HSA-202427 Phosphorylation of CD3 and TCR zeta chains 1 LFUL017488-PA KEGG: 00040+5.1.3.1 Pentose and glucuronate interconversions 1 LFUL012465-PA MetaCyc: PWY-5484 Glycolysis II (from fructose 6-phosphate) 11 LFUL001192-PA;LFUL005591-PA;LFUL011512-PA;LFUL000566-PA;LFUL011354-PA;LFUL000567-PA;LFUL011112-PA;LFUL008386-PA;LFUL011355-PA;LFUL008549-PA;LFUL015710-PA Reactome: R-HSA-381070 IRE1alpha activates chaperones 1 LFUL015267-PA KEGG: 00240+2.7.1.21 Pyrimidine metabolism 1 LFUL015135-PA KEGG: 00562+1.13.99.1 Inositol phosphate metabolism 1 LFUL005679-PA MetaCyc: PWY-7920 Complex N-linked glycan biosynthesis (plants) 1 LFUL018519-PA KEGG: 00513+2.4.1.143 Various types of N-glycan biosynthesis 1 LFUL018519-PA Reactome: R-HSA-5624958 ARL13B-mediated ciliary trafficking of INPP5E 1 LFUL001019-PA KEGG: 00020+4.1.1.32 Citrate cycle (TCA cycle) 1 LFUL010175-PA Reactome: R-HSA-9028731 Activated NTRK2 signals through FRS2 and FRS3 1 LFUL006796-PA Reactome: R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors 1 LFUL008605-PA Reactome: R-HSA-1234158 Regulation of gene expression by Hypoxia-inducible Factor 3 LFUL014616-PA;LFUL008073-PA;LFUL008074-PA Reactome: R-HSA-163560 Triglyceride catabolism 4 LFUL000334-PA;LFUL014700-PA;LFUL006251-PA;LFUL019762-PA Reactome: R-HSA-6781823 Formation of TC-NER Pre-Incision Complex 40 LFUL002488-PA;LFUL011081-PA;LFUL008550-PA;LFUL010456-PA;LFUL010467-PA;LFUL011082-PA;LFUL000317-PA;LFUL006932-PA;LFUL004537-PA;LFUL006416-PA;LFUL003758-PA;LFUL014212-PA;LFUL005659-PA;LFUL010364-PA;LFUL015346-PA;LFUL003284-PA;LFUL013037-PA;LFUL013502-PA;LFUL006931-PA;LFUL008596-PA;LFUL015756-PA;LFUL004554-PA;LFUL011164-PA;LFUL013636-PA;LFUL000113-PA;LFUL003393-PA;LFUL001373-PA;LFUL006986-PA;LFUL000305-PA;LFUL008562-PA;LFUL001890-PA;LFUL006876-PA;LFUL010468-PA;LFUL019465-PA;LFUL000117-PA;LFUL014365-PA;LFUL000593-PA;LFUL015513-PA;LFUL007187-PA;LFUL010620-PA KEGG: 00362+4.2.1.17+1.1.1.35 Benzoate degradation 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA KEGG: 00860+4.99.1.1 Porphyrin and chlorophyll metabolism 1 LFUL011673-PA Reactome: R-HSA-913709 O-linked glycosylation of mucins 15 LFUL005147-PA;LFUL006976-PA;LFUL007585-PA;LFUL018255-PA;LFUL006974-PA;LFUL019183-PA;LFUL004586-PA;LFUL002612-PA;LFUL003639-PA;LFUL003637-PA;LFUL004932-PA;LFUL003233-PA;LFUL019109-PA;LFUL012979-PA;LFUL005787-PA Reactome: R-HSA-438066 Unblocking of NMDA receptors, glutamate binding and activation 4 LFUL010848-PA;LFUL010847-PA;LFUL002885-PA;LFUL018841-PA KEGG: 00790+3.4.19.9 Folate biosynthesis 1 LFUL006877-PA Reactome: R-HSA-202424 Downstream TCR signaling 46 LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL004900-PA;LFUL009758-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL001413-PA;LFUL015886-PA;LFUL001632-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL018065-PA;LFUL017608-PA;LFUL013520-PA;LFUL005608-PA;LFUL010280-PA;LFUL014805-PA;LFUL003567-PA;LFUL016970-PA;LFUL000664-PA;LFUL018125-PA;LFUL000924-PA;LFUL017243-PA;LFUL005657-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL015255-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL005128-PA;LFUL018127-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL016470-PA;LFUL003914-PA KEGG: 00900+5.3.3.2 Terpenoid backbone biosynthesis 1 LFUL008593-PA KEGG: 00072+4.1.3.4 Synthesis and degradation of ketone bodies 1 LFUL018576-PA Reactome: R-HSA-9617629 Regulation of FOXO transcriptional activity by acetylation 2 LFUL008074-PA;LFUL008073-PA Reactome: R-HSA-1368082 RORA activates gene expression 4 LFUL008073-PA;LFUL015835-PA;LFUL008074-PA;LFUL018367-PA Reactome: R-HSA-2465910 MASTL Facilitates Mitotic Progression 1 LFUL014744-PA KEGG: 04070+2.7.11.13 Phosphatidylinositol signaling system 7 LFUL001813-PA;LFUL016458-PA;LFUL002774-PA;LFUL018399-PA;LFUL007151-PA;LFUL002773-PA;LFUL002776-PA MetaCyc: PWY-6365 D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis 1 LFUL007957-PA Reactome: R-HSA-196807 Nicotinate metabolism 6 LFUL000818-PA;LFUL009108-PA;LFUL007256-PA;LFUL005193-PA;LFUL015996-PA;LFUL019532-PA Reactome: R-HSA-5368598 Negative regulation of TCF-dependent signaling by DVL-interacting proteins 1 LFUL016359-PA MetaCyc: PWY-6519 8-amino-7-oxononanoate biosynthesis I 1 LFUL006083-PA Reactome: R-HSA-983170 Antigen Presentation: Folding, assembly and peptide loading of class I MHC 4 LFUL006151-PA;LFUL005822-PA;LFUL015267-PA;LFUL013881-PA Reactome: R-HSA-112409 RAF-independent MAPK1/3 activation 2 LFUL014137-PA;LFUL002524-PA Reactome: R-HSA-3214842 HDMs demethylate histones 4 LFUL006342-PA;LFUL001825-PA;LFUL015643-PA;LFUL001826-PA Reactome: R-HSA-2122947 NOTCH1 Intracellular Domain Regulates Transcription 19 LFUL000579-PA;LFUL008073-PA;LFUL015886-PA;LFUL016295-PA;LFUL017465-PA;LFUL001835-PA;LFUL005551-PA;LFUL003040-PA;LFUL017466-PA;LFUL015321-PA;LFUL012088-PA;LFUL001836-PA;LFUL017464-PA;LFUL009829-PA;LFUL016227-PA;LFUL008074-PA;LFUL003223-PA;LFUL004537-PA;LFUL017467-PA Reactome: R-HSA-418597 G alpha (z) signalling events 13 LFUL010531-PA;LFUL017104-PA;LFUL003893-PA;LFUL008742-PA;LFUL007151-PA;LFUL004880-PA;LFUL000620-PA;LFUL018399-PA;LFUL000640-PA;LFUL000754-PA;LFUL012255-PA;LFUL014754-PA;LFUL008741-PA Reactome: R-HSA-6791462 TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P 1 LFUL002759-PA Reactome: R-HSA-6802952 Signaling by BRAF and RAF fusions 9 LFUL001132-PA;LFUL004314-PA;LFUL002885-PA;LFUL015596-PA;LFUL004860-PA;LFUL010591-PA;LFUL006278-PA;LFUL014137-PA;LFUL015597-PA MetaCyc: PWY-5675 Nitrate reduction V (assimilatory) 1 LFUL012349-PA KEGG: 04070+3.1.3.56 Phosphatidylinositol signaling system 1 LFUL009747-PA Reactome: R-HSA-203615 eNOS activation 2 LFUL002747-PA;LFUL013047-PA KEGG: 00330+1.5.5.2 Arginine and proline metabolism 3 LFUL014994-PA;LFUL011522-PA;LFUL014993-PA Reactome: R-HSA-5657655 MGMT-mediated DNA damage reversal 1 LFUL001228-PA Reactome: R-HSA-4043916 Defective MPI causes MPI-CDG (CDG-1b) 1 LFUL006253-PA Reactome: R-HSA-375165 NCAM signaling for neurite out-growth 1 LFUL014137-PA KEGG: 00270+3.1.3.77 Cysteine and methionine metabolism 2 LFUL004263-PA;LFUL004262-PA KEGG: 00903+4.2.1.17 Limonene and pinene degradation 3 LFUL012393-PA;LFUL017943-PA;LFUL018646-PA Reactome: R-HSA-5621575 CD209 (DC-SIGN) signaling 2 LFUL008074-PA;LFUL008073-PA MetaCyc: PWY-5855 Ubiquinol-7 biosynthesis (prokaryotic) 4 LFUL002067-PA;LFUL017907-PA;LFUL000814-PA;LFUL017908-PA KEGG: 00510+2.4.1.144 N-Glycan biosynthesis 1 LFUL006201-PA MetaCyc: PWY-7888 Trna-uridine 2-thiolation (cytoplasmic) 1 LFUL005873-PA Reactome: R-HSA-2424491 DAP12 signaling 1 LFUL001462-PA Reactome: R-HSA-6802946 Signaling by moderate kinase activity BRAF mutants 6 LFUL002885-PA;LFUL011508-PA;LFUL015597-PA;LFUL015596-PA;LFUL014137-PA;LFUL001132-PA Reactome: R-HSA-141444 Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 36 LFUL013881-PA;LFUL009305-PA;LFUL009303-PA;LFUL000365-PA;LFUL011743-PA;LFUL009310-PA;LFUL015769-PA;LFUL010864-PA;LFUL001537-PA;LFUL004116-PA;LFUL002593-PA;LFUL004301-PA;LFUL005565-PA;LFUL005882-PA;LFUL004579-PA;LFUL009096-PA;LFUL002590-PA;LFUL000922-PA;LFUL015628-PA;LFUL006593-PA;LFUL002666-PA;LFUL019068-PA;LFUL007223-PA;LFUL014116-PA;LFUL004963-PA;LFUL009240-PA;LFUL000435-PA;LFUL000200-PA;LFUL015753-PA;LFUL016557-PA;LFUL016880-PA;LFUL008457-PA;LFUL015687-PA;LFUL006582-PA;LFUL010213-PA;LFUL002592-PA MetaCyc: PWY-5367 Petroselinate biosynthesis 1 LFUL006083-PA Reactome: R-HSA-933542 TRAF6 mediated NF-kB activation 2 LFUL010280-PA;LFUL003145-PA Reactome: R-HSA-112043 PLC beta mediated events 6 LFUL006196-PA;LFUL006197-PA;LFUL014147-PA;LFUL009246-PA;LFUL009249-PA;LFUL000404-PA Reactome: R-HSA-2173796 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription 8 LFUL016227-PA;LFUL008343-PA;LFUL008342-PA;LFUL002553-PA;LFUL000101-PA;LFUL013765-PA;LFUL004537-PA;LFUL015321-PA Reactome: R-HSA-5632927 Defective Mismatch Repair Associated With MSH3 1 LFUL000900-PA Reactome: R-HSA-8964026 Chylomicron clearance 5 LFUL018058-PA;LFUL005945-PA;LFUL018059-PA;LFUL019397-PA;LFUL013535-PA Reactome: R-HSA-977443 GABA receptor activation 1 LFUL018415-PA Reactome: R-HSA-176974 Unwinding of DNA 15 LFUL011919-PA;LFUL009340-PA;LFUL007704-PA;LFUL007817-PA;LFUL006670-PA;LFUL004598-PA;LFUL017714-PA;LFUL019733-PA;LFUL012288-PA;LFUL006063-PA;LFUL017711-PA;LFUL011731-PA;LFUL012130-PA;LFUL004865-PA;LFUL018575-PA KEGG: 00562+2.7.1.134+2.7.1.159 Inositol phosphate metabolism 1 LFUL007957-PA Reactome: R-HSA-6804760 Regulation of TP53 Activity through Methylation 5 LFUL004537-PA;LFUL001324-PA;LFUL000868-PA;LFUL006936-PA;LFUL013089-PA Reactome: R-HSA-3000178 ECM proteoglycans 6 LFUL003428-PA;LFUL019569-PA;LFUL002807-PA;LFUL009021-PA;LFUL004915-PA;LFUL004914-PA Reactome: R-HSA-190873 Gap junction degradation 3 LFUL003059-PA;LFUL019442-PA;LFUL007853-PA Reactome: R-HSA-379716 Cytosolic tRNA aminoacylation 21 LFUL003958-PA;LFUL004441-PA;LFUL003447-PA;LFUL013267-PA;LFUL010289-PA;LFUL009161-PA;LFUL002380-PA;LFUL002381-PA;LFUL004311-PA;LFUL017102-PA;LFUL014891-PA;LFUL010797-PA;LFUL014709-PA;LFUL011768-PA;LFUL000216-PA;LFUL003005-PA;LFUL016047-PA;LFUL001438-PA;LFUL015627-PA;LFUL003522-PA;LFUL003004-PA Reactome: R-HSA-6787639 GDP-fucose biosynthesis 2 LFUL002512-PA;LFUL017954-PA KEGG: 00970+6.1.1.10 Aminoacyl-tRNA biosynthesis 2 LFUL014405-PA;LFUL004311-PA Reactome: R-HSA-5694530 Cargo concentration in the ER 6 LFUL004109-PA;LFUL005822-PA;LFUL006151-PA;LFUL000429-PA;LFUL001626-PA;LFUL017724-PA KEGG: 00970+6.1.1.9 Aminoacyl-tRNA biosynthesis 3 LFUL007665-PA;LFUL007666-PA;LFUL005078-PA Reactome: R-HSA-1433559 Regulation of KIT signaling 1 LFUL002193-PA Reactome: R-HSA-5668599 RHO GTPases Activate NADPH Oxidases 3 LFUL014137-PA;LFUL004611-PA;LFUL009193-PA KEGG: 00983+2.4.2.3 Drug metabolism - other enzymes 1 LFUL006725-PA MetaCyc: PWY-5890 Menaquinol-10 biosynthesis 2 LFUL006592-PA;LFUL006594-PA KEGG: 00562+3.1.3.66 Inositol phosphate metabolism 2 LFUL012052-PA;LFUL012051-PA Reactome: R-HSA-432047 Passive transport by Aquaporins 10 LFUL015665-PA;LFUL011696-PA;LFUL003509-PA;LFUL018400-PA;LFUL010975-PA;LFUL003510-PA;LFUL003508-PA;LFUL011695-PA;LFUL009114-PA;LFUL003511-PA KEGG: 00240+1.3.5.2 Pyrimidine metabolism 1 LFUL003607-PA MetaCyc: PWY-7574 Propanoyl-coa degradation II 2 LFUL001447-PA;LFUL001448-PA KEGG: 00270+4.1.1.50 Cysteine and methionine metabolism 1 LFUL011332-PA Reactome: R-HSA-381771 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 5 LFUL015737-PA;LFUL000640-PA;LFUL006145-PA;LFUL017551-PA;LFUL005015-PA Reactome: R-HSA-163615 PKA activation 7 LFUL000754-PA;LFUL008742-PA;LFUL004880-PA;LFUL010531-PA;LFUL008741-PA;LFUL014754-PA;LFUL015154-PA Reactome: R-HSA-351906 Apoptotic cleavage of cell adhesion proteins 1 LFUL007567-PA Reactome: R-HSA-181429 Serotonin Neurotransmitter Release Cycle 3 LFUL014216-PA;LFUL010866-PA;LFUL010868-PA KEGG: 00230+6.3.2.6 Purine metabolism 1 LFUL017018-PA MetaCyc: PWY-5686 UMP biosynthesis I 8 LFUL014041-PA;LFUL006715-PA;LFUL014037-PA;LFUL014040-PA;LFUL003607-PA;LFUL014042-PA;LFUL006717-PA;LFUL014039-PA MetaCyc: PWY-6118 Glycerol-3-phosphate shuttle 1 LFUL000334-PA Reactome: R-HSA-168276 NS1 Mediated Effects on Host Pathways 25 LFUL000581-PA;LFUL010864-PA;LFUL016880-PA;LFUL005565-PA;LFUL000200-PA;LFUL005157-PA;LFUL006358-PA;LFUL011549-PA;LFUL004473-PA;LFUL002532-PA;LFUL013881-PA;LFUL009305-PA;LFUL009303-PA;LFUL002533-PA;LFUL008059-PA;LFUL000747-PA;LFUL016186-PA;LFUL002666-PA;LFUL006282-PA;LFUL006167-PA;LFUL015687-PA;LFUL005156-PA;LFUL013801-PA;LFUL018131-PA;LFUL009840-PA Reactome: R-HSA-164944 Nef and signal transduction 1 LFUL001602-PA KEGG: 00330+2.3.1.57 Arginine and proline metabolism 1 LFUL017216-PA MetaCyc: PWY-6147 6-hydroxymethyl-dihydropterin diphosphate biosynthesis I 2 LFUL019539-PA;LFUL004602-PA Reactome: R-HSA-5140745 WNT5A-dependent internalization of FZD2, FZD5 and ROR2 4 LFUL007853-PA;LFUL003059-PA;LFUL007491-PA;LFUL000575-PA KEGG: 00600+1.14.19.17 Sphingolipid metabolism 1 LFUL016336-PA Reactome: R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling 2 LFUL015585-PA;LFUL000232-PA KEGG: 00630+3.5.1.9 Glyoxylate and dicarboxylate metabolism 1 LFUL015273-PA MetaCyc: PWY-6731 Starch degradation III 1 LFUL012958-PA MetaCyc: PWY-7996 Menaquinol-4 biosynthesis I 2 LFUL006594-PA;LFUL006592-PA Reactome: R-HSA-5223345 Miscellaneous transport and binding events 3 LFUL000432-PA;LFUL000496-PA;LFUL014088-PA KEGG: 00310+2.1.1.60 Lysine degradation 1 LFUL000797-PA Reactome: R-HSA-2206282 MPS IIIB - Sanfilippo syndrome B 1 LFUL018950-PA Reactome: R-HSA-9665244 Resistance of ERBB2 KD mutants to sapitinib 1 LFUL010369-PA KEGG: 00750+1.4.3.5 Vitamin B6 metabolism 2 LFUL012528-PA;LFUL013559-PA Reactome: R-HSA-4551638 SUMOylation of chromatin organization proteins 25 LFUL016186-PA;LFUL008059-PA;LFUL002533-PA;LFUL009303-PA;LFUL013881-PA;LFUL002532-PA;LFUL009305-PA;LFUL005565-PA;LFUL016880-PA;LFUL011549-PA;LFUL000200-PA;LFUL005157-PA;LFUL006358-PA;LFUL000581-PA;LFUL010864-PA;LFUL006209-PA;LFUL013801-PA;LFUL007465-PA;LFUL017105-PA;LFUL009840-PA;LFUL018131-PA;LFUL006282-PA;LFUL015687-PA;LFUL005156-PA;LFUL002666-PA Reactome: R-HSA-432040 Vasopressin regulates renal water homeostasis via Aquaporins 12 LFUL003893-PA;LFUL010531-PA;LFUL017104-PA;LFUL008742-PA;LFUL004880-PA;LFUL015154-PA;LFUL000620-PA;LFUL000754-PA;LFUL000640-PA;LFUL012255-PA;LFUL008741-PA;LFUL014754-PA Reactome: R-HSA-8869496 TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation 2 LFUL008430-PA;LFUL015235-PA Reactome: R-HSA-8936459 RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function 18 LFUL001592-PA;LFUL012798-PA;LFUL008336-PA;LFUL009516-PA;LFUL005454-PA;LFUL010269-PA;LFUL019672-PA;LFUL009515-PA;LFUL015532-PA;LFUL015531-PA;LFUL004232-PA;LFUL009514-PA;LFUL011069-PA;LFUL006745-PA;LFUL015175-PA;LFUL009513-PA;LFUL010270-PA;LFUL004906-PA Reactome: R-HSA-381033 ATF6 (ATF6-alpha) activates chaperones 2 LFUL015267-PA;LFUL002083-PA MetaCyc: PWY-6613 Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate 2 LFUL003915-PA;LFUL014192-PA KEGG: 00240+2.4.2.4 Pyrimidine metabolism 1 LFUL005855-PA Reactome: R-HSA-5654712 FRS-mediated FGFR4 signaling 1 LFUL006796-PA KEGG: 00600+3.1.3.4 Sphingolipid metabolism 3 LFUL011020-PA;LFUL005920-PA;LFUL011019-PA MetaCyc: PWY-5340 Sulfate activation for sulfonation 2 LFUL014566-PA;LFUL019316-PA MetaCyc: PWY-6348 Phosphate acquisition 3 LFUL001985-PA;LFUL016357-PA;LFUL017688-PA Reactome: R-HSA-9619483 Activation of AMPK downstream of NMDARs 18 LFUL003377-PA;LFUL013561-PA;LFUL014795-PA;LFUL014800-PA;LFUL014801-PA;LFUL010020-PA;LFUL013555-PA;LFUL010681-PA;LFUL014793-PA;LFUL012256-PA;LFUL013560-PA;LFUL014799-PA;LFUL010682-PA;LFUL004646-PA;LFUL013557-PA;LFUL005590-PA;LFUL008160-PA;LFUL001585-PA Reactome: R-HSA-901042 Calnexin/calreticulin cycle 3 LFUL017984-PA;LFUL014908-PA;LFUL014909-PA Reactome: R-HSA-381038 XBP1(S) activates chaperone genes 7 LFUL004764-PA;LFUL012892-PA;LFUL017168-PA;LFUL001624-PA;LFUL017541-PA;LFUL013554-PA;LFUL004765-PA Reactome: R-HSA-156581 Methylation 4 LFUL003488-PA;LFUL012283-PA;LFUL003042-PA;LFUL011154-PA KEGG: 00983+1.17.4.1 Drug metabolism - other enzymes 19 LFUL008033-PA;LFUL015842-PA;LFUL005848-PA;LFUL003861-PA;LFUL006960-PA;LFUL019261-PA;LFUL014063-PA;LFUL019252-PA;LFUL014941-PA;LFUL004400-PA;LFUL018976-PA;LFUL016612-PA;LFUL013124-PA;LFUL017179-PA;LFUL001680-PA;LFUL008100-PA;LFUL019301-PA;LFUL004087-PA;LFUL013859-PA Reactome: R-HSA-2046105 Linoleic acid (LA) metabolism 1 LFUL000576-PA Reactome: R-HSA-110330 Recognition and association of DNA glycosylase with site containing an affected purine 2 LFUL014324-PA;LFUL004576-PA MetaCyc: PWY-6803 Phosphatidylcholine acyl editing 21 LFUL013309-PA;LFUL019491-PA;LFUL012016-PA;LFUL004585-PA;LFUL013308-PA;LFUL016033-PA;LFUL013311-PA;LFUL013307-PA;LFUL010843-PA;LFUL016034-PA;LFUL016035-PA;LFUL015933-PA;LFUL002720-PA;LFUL013310-PA;LFUL002722-PA;LFUL011621-PA;LFUL016032-PA;LFUL016881-PA;LFUL002721-PA;LFUL016031-PA;LFUL012592-PA MetaCyc: PWY-5133 Colupulone and cohumulone biosynthesis 2 LFUL006868-PA;LFUL001222-PA Reactome: R-HSA-5654726 Negative regulation of FGFR1 signaling 2 LFUL004537-PA;LFUL014137-PA KEGG: 00230+1.17.4.1 Purine metabolism 19 LFUL015842-PA;LFUL005848-PA;LFUL008033-PA;LFUL019261-PA;LFUL006960-PA;LFUL003861-PA;LFUL019252-PA;LFUL014063-PA;LFUL014941-PA;LFUL016612-PA;LFUL004400-PA;LFUL018976-PA;LFUL008100-PA;LFUL019301-PA;LFUL013124-PA;LFUL017179-PA;LFUL001680-PA;LFUL004087-PA;LFUL013859-PA MetaCyc: PWY-5103 L-isoleucine biosynthesis III 1 LFUL019679-PA Reactome: R-HSA-156584 Cytosolic sulfonation of small molecules 1 LFUL004306-PA KEGG: 00010+1.2.4.1 Glycolysis / Gluconeogenesis 1 LFUL010747-PA Reactome: R-HSA-179409 APC-Cdc20 mediated degradation of Nek2A 12 LFUL008983-PA;LFUL004085-PA;LFUL006691-PA;LFUL011827-PA;LFUL001285-PA;LFUL011394-PA;LFUL002279-PA;LFUL011826-PA;LFUL004537-PA;LFUL000448-PA;LFUL013953-PA;LFUL006381-PA KEGG: 00970+6.1.1.4 Aminoacyl-tRNA biosynthesis 2 LFUL007703-PA;LFUL001438-PA MetaCyc: PWY-6368 3-phosphoinositide degradation 6 LFUL008439-PA;LFUL012052-PA;LFUL012230-PA;LFUL012051-PA;LFUL008204-PA;LFUL014591-PA Reactome: R-HSA-4724325 Defective ALG8 causes ALG8-CDG (CDG-1h) 1 LFUL015953-PA Reactome: R-HSA-5637810 Constitutive Signaling by EGFRvIII 1 LFUL010369-PA Reactome: R-HSA-168164 Toll Like Receptor 3 (TLR3) Cascade 1 LFUL014668-PA MetaCyc: PWY-7894 Procollagen hydroxylation and glycosylation 1 LFUL012323-PA Reactome: R-HSA-203927 MicroRNA (miRNA) biogenesis 23 LFUL004526-PA;LFUL012019-PA;LFUL006931-PA;LFUL003284-PA;LFUL013037-PA;LFUL010620-PA;LFUL017051-PA;LFUL016298-PA;LFUL010364-PA;LFUL016297-PA;LFUL004525-PA;LFUL014131-PA;LFUL016296-PA;LFUL019785-PA;LFUL011518-PA;LFUL006932-PA;LFUL004524-PA;LFUL001373-PA;LFUL019805-PA;LFUL008550-PA;LFUL006660-PA;LFUL004969-PA;LFUL004968-PA MetaCyc: PWY-6134 L-tyrosine biosynthesis IV 1 LFUL004045-PA Reactome: R-HSA-110312 Translesion synthesis by REV1 14 LFUL011672-PA;LFUL002760-PA;LFUL004537-PA;LFUL003903-PA;LFUL014494-PA;LFUL000715-PA;LFUL006665-PA;LFUL001437-PA;LFUL013345-PA;LFUL011668-PA;LFUL005736-PA;LFUL011669-PA;LFUL000714-PA;LFUL008688-PA MetaCyc: PWY-5884 Wax esters biosynthesis I 18 LFUL010158-PA;LFUL002995-PA;LFUL012817-PA;LFUL012813-PA;LFUL012814-PA;LFUL012820-PA;LFUL012818-PA;LFUL012811-PA;LFUL018766-PA;LFUL012816-PA;LFUL013657-PA;LFUL018767-PA;LFUL012819-PA;LFUL008789-PA;LFUL013658-PA;LFUL010157-PA;LFUL013655-PA;LFUL013656-PA KEGG: 00310+4.2.1.17+1.1.1.35 Lysine degradation 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA Reactome: R-HSA-1362300 Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1 4 LFUL014149-PA;LFUL013765-PA;LFUL000101-PA;LFUL014016-PA Reactome: R-HSA-1296052 Ca2+ activated K+ channels 4 LFUL005338-PA;LFUL010274-PA;LFUL005339-PA;LFUL010272-PA KEGG: 00670+2.1.2.1 One carbon pool by folate 3 LFUL009609-PA;LFUL004544-PA;LFUL001565-PA Reactome: R-HSA-5205685 Pink/Parkin Mediated Mitophagy 10 LFUL015758-PA;LFUL015071-PA;LFUL004537-PA;LFUL017691-PA;LFUL018364-PA;LFUL012905-PA;LFUL018365-PA;LFUL001182-PA;LFUL008718-PA;LFUL014937-PA MetaCyc: PWY-1722 Formate assimilation into 5,10-methylenetetrahydrofolate 2 LFUL003915-PA;LFUL014192-PA Reactome: R-HSA-3371497 HSP90 chaperone cycle for steroid hormone receptors (SHR) 28 LFUL016557-PA;LFUL009755-PA;LFUL013561-PA;LFUL003377-PA;LFUL002675-PA;LFUL017541-PA;LFUL014299-PA;LFUL001537-PA;LFUL014800-PA;LFUL014795-PA;LFUL010681-PA;LFUL000669-PA;LFUL014793-PA;LFUL010020-PA;LFUL014801-PA;LFUL014303-PA;LFUL013555-PA;LFUL013560-PA;LFUL016457-PA;LFUL006593-PA;LFUL007212-PA;LFUL012256-PA;LFUL003889-PA;LFUL014799-PA;LFUL013557-PA;LFUL004646-PA;LFUL010682-PA;LFUL005184-PA MetaCyc: PWY-7179-1 Purine deoxyribonucleosides degradation II 3 LFUL011578-PA;LFUL011577-PA;LFUL003389-PA MetaCyc: PWY-1187 Glucosinolate biosynthesis from homomethionine 2 LFUL013724-PA;LFUL013723-PA MetaCyc: PWY-7224 Purine deoxyribonucleosides salvage 7 LFUL005983-PA;LFUL017852-PA;LFUL005981-PA;LFUL013982-PA;LFUL017739-PA;LFUL008636-PA;LFUL011295-PA MetaCyc: PWY-6556 Pyrimidine ribonucleosides salvage II 1 LFUL011652-PA MetaCyc: PWY-8051 Anandamide biosynthesis I 31 LFUL013307-PA;LFUL016033-PA;LFUL013311-PA;LFUL010843-PA;LFUL011019-PA;LFUL004585-PA;LFUL013308-PA;LFUL012016-PA;LFUL005920-PA;LFUL002099-PA;LFUL019491-PA;LFUL011020-PA;LFUL013309-PA;LFUL012592-PA;LFUL016031-PA;LFUL002721-PA;LFUL016881-PA;LFUL016032-PA;LFUL008878-PA;LFUL002722-PA;LFUL011621-PA;LFUL013310-PA;LFUL009878-PA;LFUL017634-PA;LFUL014100-PA;LFUL002720-PA;LFUL015933-PA;LFUL016045-PA;LFUL016603-PA;LFUL016034-PA;LFUL016035-PA MetaCyc: PWY-3341 L-proline biosynthesis III (from L-ornithine) 1 LFUL014392-PA Reactome: R-HSA-5358751 S45 mutants of beta-catenin aren't phosphorylated 4 LFUL015628-PA;LFUL007844-PA;LFUL010552-PA;LFUL009310-PA KEGG: 00720+4.2.1.3 Carbon fixation pathways in prokaryotes 2 LFUL013084-PA;LFUL012627-PA KEGG: 00790+3.5.4.16 Folate biosynthesis 2 LFUL004602-PA;LFUL019539-PA KEGG: 00564+2.7.7.41 Glycerophospholipid metabolism 2 LFUL007247-PA;LFUL013010-PA MetaCyc: PWY-6920 6-gingerol analog biosynthesis (engineered) 2 LFUL001447-PA;LFUL001448-PA MetaCyc: PWY-5826 Hypoglycin biosynthesis 6 LFUL016402-PA;LFUL003732-PA;LFUL015031-PA;LFUL016403-PA;LFUL012059-PA;LFUL012058-PA Reactome: R-HSA-2894862 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants 30 LFUL015476-PA;LFUL016295-PA;LFUL000671-PA;LFUL005973-PA;LFUL017465-PA;LFUL001835-PA;LFUL009003-PA;LFUL015886-PA;LFUL008073-PA;LFUL003906-PA;LFUL017466-PA;LFUL015321-PA;LFUL003040-PA;LFUL005551-PA;LFUL009829-PA;LFUL018390-PA;LFUL004221-PA;LFUL016227-PA;LFUL019751-PA;LFUL012088-PA;LFUL009679-PA;LFUL001836-PA;LFUL017464-PA;LFUL004537-PA;LFUL008785-PA;LFUL017467-PA;LFUL000121-PA;LFUL008074-PA;LFUL003223-PA;LFUL000672-PA Reactome: R-HSA-8854691 Interleukin-20 family signaling 1 LFUL000232-PA Reactome: R-HSA-432720 Lysosome Vesicle Biogenesis 3 LFUL010059-PA;LFUL003059-PA;LFUL013808-PA MetaCyc: PWY-6606 Guanosine nucleotides degradation II 3 LFUL011206-PA;LFUL011735-PA;LFUL011207-PA Reactome: R-HSA-9033500 TYSND1 cleaves peroxisomal proteins 4 LFUL018155-PA;LFUL015964-PA;LFUL015965-PA;LFUL018152-PA Reactome: R-HSA-1295596 Spry regulation of FGF signaling 2 LFUL014137-PA;LFUL004537-PA Reactome: R-HSA-5693571 Nonhomologous End-Joining (NHEJ) 15 LFUL011445-PA;LFUL013202-PA;LFUL004631-PA;LFUL009951-PA;LFUL001126-PA;LFUL011470-PA;LFUL006936-PA;LFUL014004-PA;LFUL015191-PA;LFUL005423-PA;LFUL002949-PA;LFUL004632-PA;LFUL002948-PA;LFUL001094-PA;LFUL013266-PA MetaCyc: PWY-6471 Peptidoglycan biosynthesis IV (Enterococcus faecium) 2 LFUL009636-PA;LFUL006200-PA KEGG: 00020+4.2.1.3 Citrate cycle (TCA cycle) 2 LFUL013084-PA;LFUL012627-PA MetaCyc: PWY-5523 5,6-dimethylbenzimidazole biosynthesis I (aerobic) 1 LFUL005319-PA Reactome: R-HSA-77350 Beta oxidation of hexanoyl-CoA to butanoyl-CoA 1 LFUL017943-PA KEGG: 00760+3.6.1.9 Nicotinate and nicotinamide metabolism 2 LFUL000002-PA;LFUL014206-PA KEGG: 00220+2.6.1.1 Arginine biosynthesis 2 LFUL011379-PA;LFUL003406-PA Reactome: R-HSA-879415 Advanced glycosylation endproduct receptor signaling 5 LFUL014908-PA;LFUL014137-PA;LFUL014909-PA;LFUL002678-PA;LFUL017984-PA KEGG: 00261+4.3.3.7 Monobactam biosynthesis 1 LFUL009128-PA Reactome: R-HSA-72649 Translation initiation complex formation 49 LFUL011563-PA;LFUL004637-PA;LFUL001962-PA;LFUL006788-PA;LFUL018772-PA;LFUL001176-PA;LFUL004420-PA;LFUL002925-PA;LFUL018435-PA;LFUL000390-PA;LFUL015341-PA;LFUL004636-PA;LFUL016269-PA;LFUL015920-PA;LFUL006675-PA;LFUL012852-PA;LFUL019701-PA;LFUL016059-PA;LFUL005171-PA;LFUL014007-PA;LFUL015591-PA;LFUL018996-PA;LFUL006873-PA;LFUL004229-PA;LFUL012271-PA;LFUL006720-PA;LFUL003947-PA;LFUL005935-PA;LFUL001102-PA;LFUL002208-PA;LFUL001681-PA;LFUL014893-PA;LFUL005636-PA;LFUL013851-PA;LFUL001717-PA;LFUL006688-PA;LFUL001937-PA;LFUL017288-PA;LFUL012702-PA;LFUL009762-PA;LFUL006445-PA;LFUL017793-PA;LFUL010852-PA;LFUL010424-PA;LFUL011000-PA;LFUL002211-PA;LFUL009630-PA;LFUL004418-PA;LFUL002324-PA MetaCyc: PWY-7039 Phosphatidate metabolism, as a signaling molecule 18 LFUL015114-PA;LFUL016207-PA;LFUL001462-PA;LFUL000379-PA;LFUL006064-PA;LFUL001461-PA;LFUL006196-PA;LFUL001109-PA;LFUL015148-PA;LFUL009158-PA;LFUL016206-PA;LFUL019695-PA;LFUL006554-PA;LFUL006553-PA;LFUL006065-PA;LFUL014147-PA;LFUL006197-PA;LFUL016455-PA Reactome: R-HSA-3301854 Nuclear Pore Complex (NPC) Disassembly 22 LFUL002666-PA;LFUL005156-PA;LFUL015687-PA;LFUL006282-PA;LFUL018131-PA;LFUL009840-PA;LFUL013801-PA;LFUL010864-PA;LFUL000581-PA;LFUL006358-PA;LFUL000200-PA;LFUL005157-PA;LFUL011549-PA;LFUL005565-PA;LFUL016880-PA;LFUL002532-PA;LFUL013881-PA;LFUL009305-PA;LFUL009303-PA;LFUL002533-PA;LFUL008059-PA;LFUL016186-PA KEGG: 00053+1.1.1.22 Ascorbate and aldarate metabolism 1 LFUL010590-PA Reactome: R-HSA-3772470 Negative regulation of TCF-dependent signaling by WNT ligand antagonists 1 LFUL000815-PA Reactome: R-HSA-3371599 Defective HLCS causes multiple carboxylase deficiency 2 LFUL004188-PA;LFUL006146-PA KEGG: 00730+3.1.3.1 Thiamine metabolism 17 LFUL013507-PA;LFUL012877-PA;LFUL012940-PA;LFUL014750-PA;LFUL015106-PA;LFUL012876-PA;LFUL019741-PA;LFUL010694-PA;LFUL013506-PA;LFUL018478-PA;LFUL000809-PA;LFUL013511-PA;LFUL018215-PA;LFUL014439-PA;LFUL013510-PA;LFUL010693-PA;LFUL014437-PA KEGG: 00240+3.1.3.5 Pyrimidine metabolism 2 LFUL011206-PA;LFUL011207-PA KEGG: 00513+2.4.1.258 Various types of N-glycan biosynthesis 1 LFUL008581-PA KEGG: 00980+1.14.14.1 Metabolism of xenobiotics by cytochrome P450 2 LFUL007894-PA;LFUL019543-PA KEGG: 00240+4.2.1.70 Pyrimidine metabolism 1 LFUL015553-PA MetaCyc: PWY-6583 Pyruvate fermentation to butanol I 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA MetaCyc: PWY-7790 UMP biosynthesis II 7 LFUL014041-PA;LFUL006717-PA;LFUL014039-PA;LFUL014037-PA;LFUL006715-PA;LFUL014040-PA;LFUL014042-PA KEGG: 00230+2.7.7.4 Purine metabolism 1 LFUL019316-PA Reactome: R-HSA-8949613 Cristae formation 16 LFUL008777-PA;LFUL008719-PA;LFUL017101-PA;LFUL000166-PA;LFUL008428-PA;LFUL007276-PA;LFUL002547-PA;LFUL017269-PA;LFUL014307-PA;LFUL014521-PA;LFUL005405-PA;LFUL007141-PA;LFUL014557-PA;LFUL014803-PA;LFUL014223-PA;LFUL016356-PA Reactome: R-HSA-975110 TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling 2 LFUL004537-PA;LFUL018800-PA Reactome: R-HSA-5358346 Hedgehog ligand biogenesis 46 LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL013277-PA;LFUL004108-PA;LFUL007684-PA;LFUL009774-PA;LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL001413-PA;LFUL005059-PA;LFUL001632-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL010331-PA;LFUL001183-PA;LFUL013520-PA;LFUL005608-PA;LFUL014805-PA;LFUL003567-PA;LFUL017168-PA;LFUL016970-PA;LFUL000664-PA;LFUL017243-PA;LFUL015255-PA;LFUL001667-PA;LFUL004537-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL005128-PA;LFUL009759-PA;LFUL005006-PA;LFUL007460-PA;LFUL005058-PA;LFUL013254-PA;LFUL006784-PA;LFUL003914-PA MetaCyc: PWY-6964 Ammonia assimilation cycle II 1 LFUL012349-PA Reactome: R-HSA-2408557 Selenocysteine synthesis 78 LFUL011278-PA;LFUL014893-PA;LFUL001681-PA;LFUL002208-PA;LFUL017656-PA;LFUL018953-PA;LFUL001102-PA;LFUL008016-PA;LFUL003947-PA;LFUL006720-PA;LFUL012271-PA;LFUL004974-PA;LFUL019054-PA;LFUL012702-PA;LFUL007583-PA;LFUL009630-PA;LFUL007358-PA;LFUL017793-PA;LFUL007452-PA;LFUL004596-PA;LFUL008669-PA;LFUL017447-PA;LFUL010862-PA;LFUL008661-PA;LFUL015696-PA;LFUL014304-PA;LFUL002925-PA;LFUL018772-PA;LFUL002249-PA;LFUL014007-PA;LFUL006675-PA;LFUL011123-PA;LFUL019701-PA;LFUL019613-PA;LFUL014225-PA;LFUL006093-PA;LFUL013851-PA;LFUL017436-PA;LFUL000050-PA;LFUL005935-PA;LFUL006255-PA;LFUL009485-PA;LFUL019500-PA;LFUL018450-PA;LFUL003221-PA;LFUL006688-PA;LFUL001717-PA;LFUL000695-PA;LFUL002673-PA;LFUL003261-PA;LFUL004537-PA;LFUL001329-PA;LFUL004418-PA;LFUL011000-PA;LFUL010852-PA;LFUL006788-PA;LFUL004637-PA;LFUL008330-PA;LFUL006902-PA;LFUL011563-PA;LFUL014709-PA;LFUL015920-PA;LFUL016479-PA;LFUL016069-PA;LFUL002950-PA;LFUL004636-PA;LFUL004420-PA;LFUL001176-PA;LFUL015591-PA;LFUL010275-PA;LFUL010697-PA;LFUL005171-PA;LFUL016059-PA;LFUL012852-PA;LFUL012372-PA;LFUL016060-PA;LFUL009487-PA;LFUL018996-PA Reactome: R-HSA-176412 Phosphorylation of the APC/C 11 LFUL006381-PA;LFUL013953-PA;LFUL000448-PA;LFUL006691-PA;LFUL011827-PA;LFUL001285-PA;LFUL004085-PA;LFUL008983-PA;LFUL011826-PA;LFUL002279-PA;LFUL011394-PA KEGG: 00380+1.2.4.2 Tryptophan metabolism 5 LFUL003940-PA;LFUL006667-PA;LFUL003935-PA;LFUL006666-PA;LFUL003936-PA Reactome: R-HSA-8948747 Regulation of PTEN localization 2 LFUL004537-PA;LFUL008562-PA KEGG: 00790+1.1.1.153 Folate biosynthesis 1 LFUL013047-PA MetaCyc: PWY-7347 Sucrose biosynthesis III 1 LFUL001099-PA MetaCyc: PWY-5381 Pyridine nucleotide cycling (plants) 4 LFUL011206-PA;LFUL011944-PA;LFUL015755-PA;LFUL011207-PA KEGG: 00480+1.8.4.2 Glutathione metabolism 1 LFUL005011-PA KEGG: 00020+2.3.1.12 Citrate cycle (TCA cycle) 1 LFUL008261-PA KEGG: 00603+3.2.1.22 Glycosphingolipid biosynthesis - globo and isoglobo series 2 LFUL015843-PA;LFUL015844-PA Reactome: R-HSA-5678520 Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2 1 LFUL001420-PA Reactome: R-HSA-5358606 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) 8 LFUL005736-PA;LFUL000900-PA;LFUL007836-PA;LFUL006665-PA;LFUL001437-PA;LFUL016724-PA;LFUL007960-PA;LFUL005720-PA Reactome: R-HSA-2022377 Metabolism of Angiotensinogen to Angiotensins 5 LFUL012137-PA;LFUL017101-PA;LFUL010621-PA;LFUL011540-PA;LFUL014330-PA Reactome: R-HSA-5602636 IKBKB deficiency causes SCID 1 LFUL010280-PA KEGG: 00062+2.3.1.199 Fatty acid elongation 16 LFUL013814-PA;LFUL012359-PA;LFUL015420-PA;LFUL013815-PA;LFUL006533-PA;LFUL012361-PA;LFUL002423-PA;LFUL013817-PA;LFUL007078-PA;LFUL013816-PA;LFUL015422-PA;LFUL013818-PA;LFUL004766-PA;LFUL012360-PA;LFUL017948-PA;LFUL001095-PA KEGG: 00450+2.7.9.3 Selenocompound metabolism 2 LFUL010732-PA;LFUL018958-PA Reactome: R-HSA-174178 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 51 LFUL009758-PA;LFUL004900-PA;LFUL017218-PA;LFUL017219-PA;LFUL015402-PA;LFUL011816-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL000448-PA;LFUL013953-PA;LFUL005608-PA;LFUL014805-PA;LFUL001632-PA;LFUL001413-PA;LFUL011826-PA;LFUL002279-PA;LFUL004085-PA;LFUL013520-PA;LFUL010331-PA;LFUL001183-PA;LFUL018065-PA;LFUL010327-PA;LFUL011827-PA;LFUL017608-PA;LFUL004537-PA;LFUL013396-PA;LFUL001667-PA;LFUL005657-PA;LFUL007901-PA;LFUL015255-PA;LFUL017243-PA;LFUL011394-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL006691-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL006381-PA;LFUL003914-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL008983-PA;LFUL005128-PA;LFUL001285-PA Reactome: R-HSA-2980766 Nuclear Envelope Breakdown 2 LFUL015121-PA;LFUL002005-PA KEGG: 00510+2.4.1.68 N-Glycan biosynthesis 1 LFUL011017-PA Reactome: R-HSA-480985 Synthesis of dolichyl-phosphate-glucose 1 LFUL000120-PA Reactome: R-HSA-180534 Vpu mediated degradation of CD4 41 LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL004900-PA;LFUL009758-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL001413-PA;LFUL015886-PA;LFUL001632-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL013520-PA;LFUL005608-PA;LFUL014805-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL017243-PA;LFUL001667-PA;LFUL004537-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL015255-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL005128-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL003914-PA KEGG: 00230+3.6.1.66 Purine metabolism 1 LFUL014206-PA MetaCyc: PWY-5269 Cardiolipin biosynthesis II 2 LFUL014211-PA;LFUL001902-PA MetaCyc: PWY-5665 Vanillin biosynthesis I 2 LFUL019543-PA;LFUL007894-PA MetaCyc: PWY-6281 L-selenocysteine biosynthesis II (archaea and eukaryotes) 8 LFUL008058-PA;LFUL010732-PA;LFUL011093-PA;LFUL018958-PA;LFUL014709-PA;LFUL016479-PA;LFUL019613-PA;LFUL014710-PA KEGG: 00620+4.1.1.32 Pyruvate metabolism 1 LFUL010175-PA KEGG: 00983+2.7.4.6 Drug metabolism - other enzymes 7 LFUL008636-PA;LFUL011295-PA;LFUL005983-PA;LFUL017852-PA;LFUL005981-PA;LFUL017739-PA;LFUL013982-PA Reactome: R-HSA-435368 Zinc efflux and compartmentalization by the SLC30 family 3 LFUL018263-PA;LFUL008953-PA;LFUL008340-PA KEGG: 00520+2.7.1.59 Amino sugar and nucleotide sugar metabolism 1 LFUL003416-PA MetaCyc: PWY-5669 Phosphatidylserine and phosphatidylethanolamine biosynthesis I 1 LFUL011031-PA MetaCyc: PWY-5049 Rosmarinic acid biosynthesis II 2 LFUL004047-PA;LFUL004046-PA KEGG: 00720+6.2.1.1 Carbon fixation pathways in prokaryotes 2 LFUL006868-PA;LFUL001222-PA MetaCyc: PWY-7664 Oleate biosynthesis IV (anaerobic) 1 LFUL006083-PA MetaCyc: PWY-6837 Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent) 2 LFUL001448-PA;LFUL001447-PA Reactome: R-HSA-4549349 Defective ALG2 causes ALG2-CDG (CDG-1i) 1 LFUL013826-PA MetaCyc: PWY-6111 Mitochondrial L-carnitine shuttle 1 LFUL004873-PA Reactome: R-HSA-8950505 Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation 8 LFUL005913-PA;LFUL006774-PA;LFUL006775-PA;LFUL002759-PA;LFUL005324-PA;LFUL000159-PA;LFUL009144-PA;LFUL006786-PA MetaCyc: PWY-7857 Adlupulone and adhumulone biosynthesis 2 LFUL006868-PA;LFUL001222-PA Reactome: R-HSA-9665249 Resistance of ERBB2 KD mutants to afatinib 1 LFUL010369-PA Reactome: R-HSA-77387 Insulin receptor recycling 15 LFUL010201-PA;LFUL006476-PA;LFUL009771-PA;LFUL018924-PA;LFUL006212-PA;LFUL008406-PA;LFUL009162-PA;LFUL010191-PA;LFUL010662-PA;LFUL006787-PA;LFUL011205-PA;LFUL011203-PA;LFUL003394-PA;LFUL011204-PA;LFUL008957-PA KEGG: 00230+4.3.2.2 Purine metabolism 1 LFUL001229-PA Reactome: R-HSA-8849469 PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 1 LFUL004537-PA Reactome: R-HSA-3299685 Detoxification of Reactive Oxygen Species 28 LFUL010428-PA;LFUL007459-PA;LFUL017725-PA;LFUL019187-PA;LFUL019446-PA;LFUL005665-PA;LFUL000524-PA;LFUL008369-PA;LFUL000523-PA;LFUL013822-PA;LFUL006005-PA;LFUL004250-PA;LFUL011210-PA;LFUL007112-PA;LFUL013424-PA;LFUL000482-PA;LFUL002660-PA;LFUL007214-PA;LFUL010734-PA;LFUL007046-PA;LFUL011882-PA;LFUL000236-PA;LFUL000159-PA;LFUL001915-PA;LFUL013423-PA;LFUL002198-PA;LFUL000521-PA;LFUL007825-PA MetaCyc: PWY-6397 Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis 1 LFUL006901-PA MetaCyc: PWY-7205 CMP phosphorylation 7 LFUL008636-PA;LFUL011295-PA;LFUL005983-PA;LFUL017852-PA;LFUL005981-PA;LFUL013982-PA;LFUL017739-PA MetaCyc: PWY-7255 Ergothioneine biosynthesis I (bacteria) 2 LFUL008713-PA;LFUL019657-PA Reactome: R-HSA-77285 Beta oxidation of myristoyl-CoA to lauroyl-CoA 1 LFUL017943-PA KEGG: 00290+4.2.1.9 Valine, leucine and isoleucine biosynthesis 1 LFUL019679-PA Reactome: R-HSA-209543 p75NTR recruits signalling complexes 3 LFUL018800-PA;LFUL012905-PA;LFUL004537-PA Reactome: R-HSA-8986944 Transcriptional Regulation by MECP2 11 LFUL004232-PA;LFUL015532-PA;LFUL015531-PA;LFUL019785-PA;LFUL005454-PA;LFUL016296-PA;LFUL006660-PA;LFUL016297-PA;LFUL016298-PA;LFUL019805-PA;LFUL006745-PA MetaCyc: PWY-2821 Glucosinolate biosynthesis from phenylalanine 2 LFUL013723-PA;LFUL013724-PA KEGG: 00230+2.7.1.20 Purine metabolism 1 LFUL017738-PA Reactome: R-HSA-9033241 Peroxisomal protein import 18 LFUL015964-PA;LFUL011326-PA;LFUL019446-PA;LFUL002782-PA;LFUL015965-PA;LFUL001447-PA;LFUL010581-PA;LFUL013004-PA;LFUL018152-PA;LFUL014588-PA;LFUL018619-PA;LFUL002209-PA;LFUL007854-PA;LFUL018072-PA;LFUL018155-PA;LFUL002783-PA;LFUL004537-PA;LFUL007246-PA Reactome: R-HSA-5083632 Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) 3 LFUL018255-PA;LFUL004586-PA;LFUL019109-PA MetaCyc: PWY-2301 Myo-inositol biosynthesis 2 LFUL003784-PA;LFUL014193-PA KEGG: 00564+1.1.1.94 Glycerophospholipid metabolism 2 LFUL016130-PA;LFUL016131-PA Reactome: R-HSA-1234176 Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 44 LFUL014805-PA;LFUL012646-PA;LFUL005608-PA;LFUL013520-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL001632-PA;LFUL001413-PA;LFUL017218-PA;LFUL017219-PA;LFUL014616-PA;LFUL015402-PA;LFUL011816-PA;LFUL009758-PA;LFUL004900-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL003914-PA;LFUL004885-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL005128-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL001667-PA;LFUL004537-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL015255-PA;LFUL017243-PA;LFUL002212-PA;LFUL000664-PA;LFUL016970-PA;LFUL003567-PA KEGG: 00260+1.4.4.2 Glycine, serine and threonine metabolism 2 LFUL013283-PA;LFUL013747-PA KEGG: 00240+2.4.2.3 Pyrimidine metabolism 1 LFUL006725-PA Reactome: R-HSA-389957 Prefoldin mediated transfer of substrate to CCT/TriC 15 LFUL011755-PA;LFUL012348-PA;LFUL001900-PA;LFUL010663-PA;LFUL007840-PA;LFUL017103-PA;LFUL009144-PA;LFUL005926-PA;LFUL001283-PA;LFUL007016-PA;LFUL007809-PA;LFUL001282-PA;LFUL016588-PA;LFUL000920-PA;LFUL004185-PA Reactome: R-HSA-140180 COX reactions 1 LFUL002455-PA Reactome: R-HSA-4419969 Depolymerisation of the Nuclear Lamina 5 LFUL015121-PA;LFUL002005-PA;LFUL001684-PA;LFUL011020-PA;LFUL011019-PA MetaCyc: PWY-7661 Protein N-glycosylation (Haloferax volcanii) 1 LFUL005787-PA MetaCyc: PWY-8013 UDP-N-acetyl-D-galactosamine biosynthesis III 2 LFUL002889-PA;LFUL001099-PA KEGG: 00720+6.4.1.2 Carbon fixation pathways in prokaryotes 1 LFUL005606-PA MetaCyc: PWY-7238 Sucrose biosynthesis II 4 LFUL012958-PA;LFUL008565-PA;LFUL001099-PA;LFUL003990-PA MetaCyc: PWY-7654 (8E,10E)-dodeca-8,10-dienol biosynthesis 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA Reactome: R-HSA-5609977 Defective GALE can cause Epimerase-deficiency galactosemia (EDG) 1 LFUL006901-PA MetaCyc: PWY-7343 UDP-alpha-D-glucose biosynthesis I 1 LFUL008565-PA KEGG: 00130+2.1.1.222+2.1.1.64 Ubiquinone and other terpenoid-quinone biosynthesis 1 LFUL002067-PA Reactome: R-HSA-75955 RNA Polymerase II Transcription Elongation 41 LFUL010468-PA;LFUL004921-PA;LFUL002536-PA;LFUL008815-PA;LFUL008343-PA;LFUL001373-PA;LFUL002527-PA;LFUL003393-PA;LFUL013636-PA;LFUL008827-PA;LFUL008342-PA;LFUL016324-PA;LFUL007352-PA;LFUL010620-PA;LFUL018856-PA;LFUL015513-PA;LFUL008825-PA;LFUL004531-PA;LFUL010850-PA;LFUL004208-PA;LFUL003397-PA;LFUL006932-PA;LFUL001415-PA;LFUL016326-PA;LFUL010467-PA;LFUL010456-PA;LFUL008550-PA;LFUL004885-PA;LFUL004554-PA;LFUL016449-PA;LFUL002212-PA;LFUL006931-PA;LFUL000398-PA;LFUL007672-PA;LFUL013037-PA;LFUL003284-PA;LFUL010364-PA;LFUL014212-PA;LFUL014608-PA;LFUL006416-PA;LFUL003797-PA Reactome: R-HSA-8948751 Regulation of PTEN stability and activity 47 LFUL005608-PA;LFUL014805-PA;LFUL001413-PA;LFUL001632-PA;LFUL001183-PA;LFUL010331-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL013520-PA;LFUL004900-PA;LFUL012890-PA;LFUL009758-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL003913-PA;LFUL012888-PA;LFUL011817-PA;LFUL010441-PA;LFUL013277-PA;LFUL007162-PA;LFUL009774-PA;LFUL007684-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL005953-PA;LFUL003914-PA;LFUL012889-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL005128-PA;LFUL004665-PA;LFUL017243-PA;LFUL004537-PA;LFUL007901-PA;LFUL001667-PA;LFUL013396-PA;LFUL005657-PA;LFUL004666-PA;LFUL015255-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA MetaCyc: PWY-5664 Erythro-tetrahydrobiopterin biosynthesis II 3 LFUL010398-PA;LFUL004602-PA;LFUL019539-PA Reactome: R-HSA-428890 Role of ABL in ROBO-SLIT signaling 3 LFUL002340-PA;LFUL009096-PA;LFUL015332-PA KEGG: 00230+2.7.1.25 Purine metabolism 1 LFUL014566-PA Reactome: R-HSA-381183 ATF6 (ATF6-alpha) activates chaperone genes 4 LFUL001175-PA;LFUL008294-PA;LFUL015112-PA;LFUL015267-PA MetaCyc: PWY-5136 Fatty acid beta-oxidation II (plant peroxisome) 5 LFUL018646-PA;LFUL001447-PA;LFUL001448-PA;LFUL017943-PA;LFUL012393-PA MetaCyc: PWY-5892 Menaquinol-12 biosynthesis 2 LFUL006592-PA;LFUL006594-PA KEGG: 00740+3.1.3.2 Riboflavin metabolism 3 LFUL017688-PA;LFUL001985-PA;LFUL016357-PA KEGG: 00020+2.3.3.8 Citrate cycle (TCA cycle) 1 LFUL016366-PA KEGG: 00600+2.4.1.80 Sphingolipid metabolism 1 LFUL014857-PA MetaCyc: PWY-5537 Pyruvate fermentation to acetate V 4 LFUL006472-PA;LFUL005914-PA;LFUL004029-PA;LFUL016366-PA MetaCyc: PWY-7805 (aminomethyl)phosphonate degradation 4 LFUL004386-PA;LFUL004778-PA;LFUL004695-PA;LFUL007408-PA KEGG: 00052+5.1.3.2 Galactose metabolism 1 LFUL006901-PA KEGG: 00562+5.5.1.4 Inositol phosphate metabolism 1 LFUL014193-PA MetaCyc: PWY-7159 3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent) 4 LFUL001555-PA;LFUL001554-PA;LFUL007802-PA;LFUL000195-PA Reactome: R-HSA-399997 Acetylcholine regulates insulin secretion 1 LFUL006196-PA MetaCyc: PWY-5177 Glutaryl-coa degradation 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA KEGG: 00680+2.1.2.1 Methane metabolism 3 LFUL009609-PA;LFUL004544-PA;LFUL001565-PA MetaCyc: PWY-6883 Pyruvate fermentation to butanol II (engineered) 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA Reactome: R-HSA-1482801 Acyl chain remodelling of PS 13 LFUL012016-PA;LFUL008299-PA;LFUL004585-PA;LFUL013308-PA;LFUL008298-PA;LFUL011621-PA;LFUL016881-PA;LFUL013311-PA;LFUL008296-PA;LFUL013309-PA;LFUL002457-PA;LFUL008302-PA;LFUL008301-PA Reactome: R-HSA-8951671 RUNX3 regulates YAP1-mediated transcription 4 LFUL015463-PA;LFUL015462-PA;LFUL000001-PA;LFUL015464-PA KEGG: 00460+2.3.2.2 Cyanoamino acid metabolism 6 LFUL012059-PA;LFUL012058-PA;LFUL016403-PA;LFUL016402-PA;LFUL015031-PA;LFUL003732-PA MetaCyc: PWY-2941 L-lysine biosynthesis II 1 LFUL009128-PA KEGG: 00510+2.4.1.267 N-Glycan biosynthesis 1 LFUL008663-PA KEGG: 00520+2.7.1.1 Amino sugar and nucleotide sugar metabolism 3 LFUL004281-PA;LFUL003646-PA;LFUL004280-PA KEGG: 00471+3.5.1.2 D-Glutamine and D-glutamate metabolism 1 LFUL003072-PA Reactome: R-HSA-5689877 Josephin domain DUBs 6 LFUL005006-PA;LFUL002689-PA;LFUL006338-PA;LFUL006095-PA;LFUL008718-PA;LFUL004537-PA Reactome: R-HSA-5649702 APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway 1 LFUL013770-PA KEGG: 00332+2.7.2.11+1.2.1.41 Carbapenem biosynthesis 1 LFUL013157-PA Reactome: R-HSA-4720475 Defective ALG3 causes ALG3-CDG (CDG-1d) 1 LFUL008581-PA Reactome: R-HSA-71737 Pyrophosphate hydrolysis 2 LFUL004778-PA;LFUL004386-PA Reactome: R-HSA-611105 Respiratory electron transport 61 LFUL007406-PA;LFUL011296-PA;LFUL008184-PA;LFUL008168-PA;LFUL010627-PA;LFUL013397-PA;LFUL015993-PA;LFUL004931-PA;LFUL002377-PA;LFUL002526-PA;LFUL003448-PA;LFUL005932-PA;LFUL000213-PA;LFUL001123-PA;LFUL012076-PA;LFUL015629-PA;LFUL000692-PA;LFUL006294-PA;LFUL002198-PA;LFUL017055-PA;LFUL010397-PA;LFUL015048-PA;LFUL004382-PA;LFUL001874-PA;LFUL006872-PA;LFUL004490-PA;LFUL007046-PA;LFUL017278-PA;LFUL004491-PA;LFUL014938-PA;LFUL009677-PA;LFUL008249-PA;LFUL004515-PA;LFUL017369-PA;LFUL007423-PA;LFUL013541-PA;LFUL012650-PA;LFUL012961-PA;LFUL008865-PA;LFUL008432-PA;LFUL007407-PA;LFUL006179-PA;LFUL009243-PA;LFUL017526-PA;LFUL012347-PA;LFUL002690-PA;LFUL013398-PA;LFUL017054-PA;LFUL001081-PA;LFUL017527-PA;LFUL008263-PA;LFUL005596-PA;LFUL016410-PA;LFUL013539-PA;LFUL015837-PA;LFUL002772-PA;LFUL003931-PA;LFUL001525-PA;LFUL001009-PA;LFUL003021-PA;LFUL008459-PA Reactome: R-HSA-73856 RNA Polymerase II Transcription Termination 39 LFUL002379-PA;LFUL018008-PA;LFUL016230-PA;LFUL014935-PA;LFUL002148-PA;LFUL000565-PA;LFUL001011-PA;LFUL016879-PA;LFUL011823-PA;LFUL017090-PA;LFUL016599-PA;LFUL001669-PA;LFUL005876-PA;LFUL009571-PA;LFUL003133-PA;LFUL003763-PA;LFUL005874-PA;LFUL017088-PA;LFUL016290-PA;LFUL016786-PA;LFUL004759-PA;LFUL005950-PA;LFUL011758-PA;LFUL002514-PA;LFUL003765-PA;LFUL017089-PA;LFUL014785-PA;LFUL005875-PA;LFUL001187-PA;LFUL004758-PA;LFUL004782-PA;LFUL006595-PA;LFUL015919-PA;LFUL001010-PA;LFUL005901-PA;LFUL000564-PA;LFUL017085-PA;LFUL009060-PA;LFUL011279-PA MetaCyc: PWY-6549 L-glutamine biosynthesis III 3 LFUL012684-PA;LFUL006558-PA;LFUL012349-PA Reactome: R-HSA-2426168 Activation of gene expression by SREBF (SREBP) 10 LFUL001175-PA;LFUL011043-PA;LFUL005724-PA;LFUL018367-PA;LFUL015835-PA;LFUL007555-PA;LFUL015112-PA;LFUL006083-PA;LFUL005606-PA;LFUL015364-PA Reactome: R-HSA-175474 Assembly Of The HIV Virion 1 LFUL004537-PA KEGG: 00511+3.2.1.51 Other glycan degradation 1 LFUL012072-PA MetaCyc: PWY-5905 Hypusine biosynthesis 1 LFUL010233-PA KEGG: 00010+2.7.2.3 Glycolysis / Gluconeogenesis 1 LFUL008549-PA Reactome: R-HSA-1660517 Synthesis of PIPs at the late endosome membrane 2 LFUL002733-PA;LFUL004611-PA KEGG: 00563+3.5.1.89 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 1 LFUL007603-PA MetaCyc: PWY-7417 Phospholipid remodeling (phosphatidate, yeast) 25 LFUL016033-PA;LFUL013307-PA;LFUL013311-PA;LFUL010843-PA;LFUL013308-PA;LFUL004585-PA;LFUL012016-PA;LFUL002099-PA;LFUL019491-PA;LFUL013309-PA;LFUL012592-PA;LFUL016031-PA;LFUL002721-PA;LFUL016881-PA;LFUL016032-PA;LFUL008878-PA;LFUL011621-PA;LFUL002722-PA;LFUL013310-PA;LFUL009878-PA;LFUL017634-PA;LFUL002720-PA;LFUL016045-PA;LFUL016035-PA;LFUL016034-PA MetaCyc: PWY-4041 Gamma-glutamyl cycle 8 LFUL003732-PA;LFUL015031-PA;LFUL007702-PA;LFUL016403-PA;LFUL007701-PA;LFUL012059-PA;LFUL012058-PA;LFUL016402-PA MetaCyc: PWY-5142 Acyl-[acyl-carrier protein] thioesterase pathway 1 LFUL006083-PA MetaCyc: PWY-6823 Molybdenum cofactor biosynthesis 5 LFUL009929-PA;LFUL004972-PA;LFUL004970-PA;LFUL003909-PA;LFUL009927-PA Reactome: R-HSA-674695 RNA Polymerase II Pre-transcription Events 58 LFUL016703-PA;LFUL004051-PA;LFUL016324-PA;LFUL008342-PA;LFUL013957-PA;LFUL007352-PA;LFUL015513-PA;LFUL008825-PA;LFUL010620-PA;LFUL018856-PA;LFUL018855-PA;LFUL019760-PA;LFUL004208-PA;LFUL010850-PA;LFUL003397-PA;LFUL004531-PA;LFUL004921-PA;LFUL010468-PA;LFUL001373-PA;LFUL008343-PA;LFUL008815-PA;LFUL005318-PA;LFUL002536-PA;LFUL002527-PA;LFUL016338-PA;LFUL000564-PA;LFUL013636-PA;LFUL008827-PA;LFUL003393-PA;LFUL016449-PA;LFUL017944-PA;LFUL004554-PA;LFUL000398-PA;LFUL006931-PA;LFUL002212-PA;LFUL000565-PA;LFUL015240-PA;LFUL014212-PA;LFUL010364-PA;LFUL004050-PA;LFUL003284-PA;LFUL013037-PA;LFUL007672-PA;LFUL003797-PA;LFUL016337-PA;LFUL004052-PA;LFUL014608-PA;LFUL006416-PA;LFUL006932-PA;LFUL016326-PA;LFUL014887-PA;LFUL001415-PA;LFUL010456-PA;LFUL010467-PA;LFUL014888-PA;LFUL004885-PA;LFUL008550-PA;LFUL000689-PA Reactome: R-HSA-9027277 Erythropoietin activates Phospholipase C gamma (PLCG) 1 LFUL001462-PA MetaCyc: PWY-7573 GDP-mycosamine biosynthesis 1 LFUL002512-PA MetaCyc: PWY-8043 Ophthalmate biosynthesis 3 LFUL003123-PA;LFUL008713-PA;LFUL019657-PA Reactome: R-HSA-9604323 Negative regulation of NOTCH4 signaling 40 LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL009758-PA;LFUL001183-PA;LFUL010331-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL013520-PA;LFUL001413-PA;LFUL015886-PA;LFUL001632-PA;LFUL014805-PA;LFUL005608-PA;LFUL000664-PA;LFUL016970-PA;LFUL017243-PA;LFUL007901-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL015255-PA;LFUL005128-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL003914-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA KEGG: 00983+2.3.1.5 Drug metabolism - other enzymes 1 LFUL000219-PA Reactome: R-HSA-77075 RNA Pol II CTD phosphorylation and interaction with CE 24 LFUL016326-PA;LFUL001373-PA;LFUL006932-PA;LFUL010468-PA;LFUL003393-PA;LFUL008550-PA;LFUL013636-PA;LFUL008827-PA;LFUL010467-PA;LFUL010456-PA;LFUL006931-PA;LFUL004554-PA;LFUL016324-PA;LFUL000254-PA;LFUL006416-PA;LFUL006150-PA;LFUL003284-PA;LFUL010620-PA;LFUL018856-PA;LFUL013037-PA;LFUL015513-PA;LFUL008825-PA;LFUL010364-PA;LFUL014212-PA Reactome: R-HSA-159418 Recycling of bile acids and salts 1 LFUL001420-PA Reactome: R-HSA-6791461 RPIA deficiency: failed conversion of RU5P to R5P 1 LFUL005639-PA KEGG: 00310+4.2.1.17 Lysine degradation 1 LFUL017943-PA Reactome: R-HSA-8856825 Cargo recognition for clathrin-mediated endocytosis 28 LFUL000575-PA;LFUL007491-PA;LFUL011081-PA;LFUL005095-PA;LFUL002488-PA;LFUL013732-PA;LFUL016812-PA;LFUL007853-PA;LFUL005945-PA;LFUL000305-PA;LFUL001890-PA;LFUL011082-PA;LFUL000199-PA;LFUL018058-PA;LFUL006876-PA;LFUL019465-PA;LFUL004537-PA;LFUL014734-PA;LFUL013808-PA;LFUL018059-PA;LFUL005659-PA;LFUL015346-PA;LFUL019397-PA;LFUL013535-PA;LFUL003059-PA;LFUL001802-PA;LFUL002676-PA;LFUL015756-PA KEGG: 00670+1.5.1.5+3.5.4.9 One carbon pool by folate 2 LFUL014192-PA;LFUL003915-PA Reactome: R-HSA-434316 Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion 1 LFUL006196-PA MetaCyc: PWY-5872 Ubiquinol-10 biosynthesis (eukaryotic) 4 LFUL002067-PA;LFUL017908-PA;LFUL000814-PA;LFUL017907-PA KEGG: 00860+2.3.1.37 Porphyrin and chlorophyll metabolism 1 LFUL017816-PA KEGG: 00630+2.1.2.1 Glyoxylate and dicarboxylate metabolism 3 LFUL001565-PA;LFUL004544-PA;LFUL009609-PA MetaCyc: PWY-622 Starch biosynthesis 4 LFUL014478-PA;LFUL014477-PA;LFUL007973-PA;LFUL001099-PA MetaCyc: PWY-6364 D-myo-inositol (1,3,4)-trisphosphate biosynthesis 1 LFUL009747-PA Reactome: R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling 3 LFUL004533-PA;LFUL004116-PA;LFUL014137-PA Reactome: R-HSA-6811438 Intra-Golgi traffic 25 LFUL001925-PA;LFUL000528-PA;LFUL017267-PA;LFUL017228-PA;LFUL012651-PA;LFUL012613-PA;LFUL015280-PA;LFUL001812-PA;LFUL018558-PA;LFUL014962-PA;LFUL018561-PA;LFUL000842-PA;LFUL003767-PA;LFUL005788-PA;LFUL015279-PA;LFUL003212-PA;LFUL008800-PA;LFUL019233-PA;LFUL012653-PA;LFUL014961-PA;LFUL014963-PA;LFUL003472-PA;LFUL008799-PA;LFUL018560-PA;LFUL014959-PA KEGG: 04070+2.7.1.107 Phosphatidylinositol signaling system 9 LFUL019695-PA;LFUL016206-PA;LFUL015114-PA;LFUL016207-PA;LFUL006065-PA;LFUL006554-PA;LFUL006064-PA;LFUL000379-PA;LFUL006553-PA KEGG: 00592+3.1.1.4 alpha-Linolenic acid metabolism 20 LFUL011621-PA;LFUL002722-PA;LFUL013310-PA;LFUL016031-PA;LFUL012592-PA;LFUL016032-PA;LFUL016881-PA;LFUL002721-PA;LFUL016034-PA;LFUL016035-PA;LFUL002720-PA;LFUL013308-PA;LFUL004585-PA;LFUL012016-PA;LFUL013311-PA;LFUL016033-PA;LFUL013307-PA;LFUL010843-PA;LFUL013309-PA;LFUL019491-PA Reactome: R-HSA-171319 Telomere Extension By Telomerase 6 LFUL003424-PA;LFUL011456-PA;LFUL005368-PA;LFUL005367-PA;LFUL006279-PA;LFUL005366-PA Reactome: R-HSA-193692 Regulated proteolysis of p75NTR 5 LFUL009003-PA;LFUL008785-PA;LFUL005973-PA;LFUL003906-PA;LFUL018390-PA MetaCyc: PWY-7602 Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes) 18 LFUL015420-PA;LFUL013815-PA;LFUL010698-PA;LFUL013814-PA;LFUL012359-PA;LFUL012361-PA;LFUL002423-PA;LFUL006533-PA;LFUL004766-PA;LFUL015422-PA;LFUL013818-PA;LFUL012360-PA;LFUL013817-PA;LFUL013816-PA;LFUL007078-PA;LFUL017948-PA;LFUL001095-PA;LFUL001272-PA KEGG: 00520+5.1.3.2 Amino sugar and nucleotide sugar metabolism 1 LFUL006901-PA KEGG: 00970+6.1.1.5 Aminoacyl-tRNA biosynthesis 2 LFUL000481-PA;LFUL004441-PA Reactome: R-HSA-189085 Digestion of dietary carbohydrate 72 LFUL004317-PA;LFUL013923-PA;LFUL000237-PA;LFUL007946-PA;LFUL000208-PA;LFUL016105-PA;LFUL016564-PA;LFUL013261-PA;LFUL006573-PA;LFUL017281-PA;LFUL017951-PA;LFUL014661-PA;LFUL009233-PA;LFUL009656-PA;LFUL015301-PA;LFUL009227-PA;LFUL013111-PA;LFUL009225-PA;LFUL011270-PA;LFUL013525-PA;LFUL004318-PA;LFUL007053-PA;LFUL000955-PA;LFUL009222-PA;LFUL013264-PA;LFUL014895-PA;LFUL000545-PA;LFUL004319-PA;LFUL014064-PA;LFUL003499-PA;LFUL007054-PA;LFUL009229-PA;LFUL003500-PA;LFUL009217-PA;LFUL009234-PA;LFUL009221-PA;LFUL014518-PA;LFUL003830-PA;LFUL016103-PA;LFUL014519-PA;LFUL012001-PA;LFUL006576-PA;LFUL015782-PA;LFUL014516-PA;LFUL012000-PA;LFUL017388-PA;LFUL009230-PA;LFUL000780-PA;LFUL016805-PA;LFUL007976-PA;LFUL012427-PA;LFUL011393-PA;LFUL009232-PA;LFUL007038-PA;LFUL001844-PA;LFUL013262-PA;LFUL000209-PA;LFUL000212-PA;LFUL009218-PA;LFUL016106-PA;LFUL015151-PA;LFUL009231-PA;LFUL010625-PA;LFUL009226-PA;LFUL013924-PA;LFUL013085-PA;LFUL007259-PA;LFUL007973-PA;LFUL013263-PA;LFUL009223-PA;LFUL009655-PA;LFUL013357-PA KEGG: 05170+2.7.11.1 Human immunodeficiency virus 1 infection 50 LFUL000550-PA;LFUL010552-PA;LFUL004423-PA;LFUL000247-PA;LFUL013749-PA;LFUL004673-PA;LFUL006034-PA;LFUL008438-PA;LFUL012699-PA;LFUL016077-PA;LFUL000058-PA;LFUL017285-PA;LFUL009466-PA;LFUL000059-PA;LFUL001475-PA;LFUL004296-PA;LFUL010551-PA;LFUL013361-PA;LFUL002766-PA;LFUL018447-PA;LFUL018448-PA;LFUL016885-PA;LFUL001476-PA;LFUL000251-PA;LFUL010118-PA;LFUL001132-PA;LFUL015132-PA;LFUL008160-PA;LFUL014180-PA;LFUL012191-PA;LFUL000248-PA;LFUL019451-PA;LFUL003065-PA;LFUL015336-PA;LFUL005999-PA;LFUL003125-PA;LFUL014316-PA;LFUL000595-PA;LFUL014459-PA;LFUL006936-PA;LFUL000249-PA;LFUL000250-PA;LFUL006176-PA;LFUL016685-PA;LFUL000924-PA;LFUL006336-PA;LFUL015097-PA;LFUL003791-PA;LFUL015598-PA;LFUL001467-PA Reactome: R-HSA-73863 RNA Polymerase I Transcription Termination 25 LFUL013636-PA;LFUL003393-PA;LFUL010456-PA;LFUL010467-PA;LFUL001373-PA;LFUL011953-PA;LFUL009752-PA;LFUL000106-PA;LFUL002481-PA;LFUL010061-PA;LFUL001785-PA;LFUL010468-PA;LFUL006932-PA;LFUL006416-PA;LFUL014212-PA;LFUL010364-PA;LFUL015513-PA;LFUL013037-PA;LFUL003284-PA;LFUL010060-PA;LFUL001784-PA;LFUL006931-PA;LFUL011954-PA;LFUL003875-PA;LFUL004554-PA KEGG: 00630+6.4.1.3 Glyoxylate and dicarboxylate metabolism 1 LFUL006146-PA KEGG: 00360+1.14.16.1 Phenylalanine metabolism 1 LFUL004045-PA MetaCyc: PWY-7282 4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis 5 LFUL006014-PA;LFUL013559-PA;LFUL012528-PA;LFUL017016-PA;LFUL009425-PA MetaCyc: PWY-7901 Glucosinolate biosynthesis from tyrosine 2 LFUL013724-PA;LFUL013723-PA KEGG: 00040+2.7.7.9 Pentose and glucuronate interconversions 1 LFUL008565-PA MetaCyc: PWY-8099 Tetrahydropteridine recycling 1 LFUL000107-PA Reactome: R-HSA-111464 SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes 5 LFUL016074-PA;LFUL004784-PA;LFUL018372-PA;LFUL002198-PA;LFUL007046-PA Reactome: R-HSA-3000497 Scavenging by Class H Receptors 5 LFUL018059-PA;LFUL005945-PA;LFUL018058-PA;LFUL013535-PA;LFUL019397-PA Reactome: R-HSA-77108 Utilization of Ketone Bodies 1 LFUL003985-PA Reactome: R-HSA-141430 Inactivation of APC/C via direct inhibition of the APC/C complex 11 LFUL002279-PA;LFUL011826-PA;LFUL011394-PA;LFUL006691-PA;LFUL011827-PA;LFUL001285-PA;LFUL008983-PA;LFUL004085-PA;LFUL006381-PA;LFUL013953-PA;LFUL000448-PA Reactome: R-HSA-416572 Sema4D induced cell migration and growth-cone collapse 1 LFUL000248-PA Reactome: R-HSA-5685942 HDR through Homologous Recombination (HRR) 38 LFUL007277-PA;LFUL019536-PA;LFUL009325-PA;LFUL004632-PA;LFUL007471-PA;LFUL004270-PA;LFUL003753-PA;LFUL007279-PA;LFUL003121-PA;LFUL001598-PA;LFUL008688-PA;LFUL006936-PA;LFUL007832-PA;LFUL011672-PA;LFUL008071-PA;LFUL003903-PA;LFUL007960-PA;LFUL004537-PA;LFUL004631-PA;LFUL005736-PA;LFUL011668-PA;LFUL014004-PA;LFUL011482-PA;LFUL002760-PA;LFUL014494-PA;LFUL006665-PA;LFUL002671-PA;LFUL007096-PA;LFUL011669-PA;LFUL001126-PA;LFUL007979-PA;LFUL013345-PA;LFUL007836-PA;LFUL005720-PA;LFUL005650-PA;LFUL014965-PA;LFUL001437-PA;LFUL010680-PA KEGG: 00330+2.5.1.22 Arginine and proline metabolism 1 LFUL005994-PA MetaCyc: PWY-5642 2,4-dinitrotoluene degradation 1 LFUL014148-PA Reactome: R-HSA-9645460 Alpha-protein kinase 1 signaling pathway 4 LFUL018125-PA;LFUL004537-PA;LFUL005189-PA;LFUL018127-PA KEGG: 00052+5.1.3.3 Galactose metabolism 1 LFUL002992-PA Reactome: R-HSA-194313 VEGF ligand-receptor interactions 2 LFUL006738-PA;LFUL006737-PA Reactome: R-HSA-193681 Ceramide signalling 1 LFUL007500-PA Reactome: R-HSA-201722 Formation of the beta-catenin:TCF transactivating complex 16 LFUL002527-PA;LFUL010269-PA;LFUL000059-PA;LFUL005993-PA;LFUL008073-PA;LFUL000579-PA;LFUL000058-PA;LFUL008074-PA;LFUL010270-PA;LFUL011069-PA;LFUL016449-PA;LFUL015174-PA;LFUL002553-PA;LFUL008435-PA;LFUL006279-PA;LFUL014004-PA Reactome: R-HSA-450513 Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA 12 LFUL010888-PA;LFUL015271-PA;LFUL003231-PA;LFUL005320-PA;LFUL000541-PA;LFUL006413-PA;LFUL018238-PA;LFUL011544-PA;LFUL008668-PA;LFUL003227-PA;LFUL013449-PA;LFUL015691-PA MetaCyc: PWY-6517 N-acetylglucosamine degradation II 1 LFUL003416-PA MetaCyc: PWY-7886 Cell-surface glycoconjugate-linked phosphocholine biosynthesis 1 LFUL001619-PA MetaCyc: PWY-5097 L-lysine biosynthesis VI 1 LFUL009128-PA KEGG: 00240+3.6.1.6 Pyrimidine metabolism 1 LFUL002917-PA Reactome: R-HSA-427413 NoRC negatively regulates rRNA expression 33 LFUL010061-PA;LFUL001785-PA;LFUL006932-PA;LFUL019792-PA;LFUL011953-PA;LFUL000106-PA;LFUL003902-PA;LFUL010456-PA;LFUL010467-PA;LFUL011954-PA;LFUL003875-PA;LFUL004554-PA;LFUL006931-PA;LFUL014212-PA;LFUL010364-PA;LFUL003284-PA;LFUL013037-PA;LFUL010060-PA;LFUL006416-PA;LFUL008336-PA;LFUL010468-PA;LFUL019841-PA;LFUL001373-PA;LFUL009752-PA;LFUL002481-PA;LFUL004703-PA;LFUL013636-PA;LFUL003393-PA;LFUL013705-PA;LFUL002298-PA;LFUL003226-PA;LFUL015513-PA;LFUL001784-PA KEGG: 00480+1.1.1.44 Glutathione metabolism 1 LFUL013845-PA Reactome: R-HSA-201681 TCF dependent signaling in response to WNT 10 LFUL004666-PA;LFUL004537-PA;LFUL000815-PA;LFUL012890-PA;LFUL014776-PA;LFUL004665-PA;LFUL000173-PA;LFUL016359-PA;LFUL012889-PA;LFUL012888-PA KEGG: 00860+1.14.14.18 Porphyrin and chlorophyll metabolism 1 LFUL005036-PA Reactome: R-HSA-6781827 Transcription-Coupled Nucleotide Excision Repair (TC-NER) 29 LFUL006931-PA;LFUL008596-PA;LFUL004554-PA;LFUL011164-PA;LFUL000117-PA;LFUL014365-PA;LFUL004537-PA;LFUL003758-PA;LFUL006416-PA;LFUL000593-PA;LFUL010364-PA;LFUL015513-PA;LFUL014212-PA;LFUL013502-PA;LFUL013037-PA;LFUL007187-PA;LFUL003284-PA;LFUL010620-PA;LFUL008562-PA;LFUL001373-PA;LFUL006986-PA;LFUL010468-PA;LFUL006932-PA;LFUL000113-PA;LFUL013636-PA;LFUL003393-PA;LFUL008550-PA;LFUL010456-PA;LFUL010467-PA Reactome: R-HSA-3270619 IRF3-mediated induction of type I IFN 4 LFUL004631-PA;LFUL002948-PA;LFUL004632-PA;LFUL002949-PA KEGG: 00531+3.2.1.35 Glycosaminoglycan degradation 2 LFUL005974-PA;LFUL017350-PA Reactome: R-HSA-5545619 XAV939 inhibits tankyrase, stabilizing AXIN 2 LFUL004666-PA;LFUL004665-PA Reactome: R-HSA-1482883 Acyl chain remodeling of DAG and TAG 1 LFUL000328-PA KEGG: 00510+2.4.1.143 N-Glycan biosynthesis 1 LFUL018519-PA MetaCyc: PWY-7291 Oleate beta-oxidation (isomerase-dependent, yeast) 2 LFUL001448-PA;LFUL001447-PA MetaCyc: PWY-7734 Quinoxaline-2-carboxylate biosynthesis 1 LFUL015273-PA Reactome: R-HSA-1799339 SRP-dependent cotranslational protein targeting to membrane 97 LFUL015591-PA;LFUL010275-PA;LFUL005171-PA;LFUL010697-PA;LFUL012852-PA;LFUL012372-PA;LFUL002678-PA;LFUL016059-PA;LFUL016060-PA;LFUL006716-PA;LFUL009487-PA;LFUL018996-PA;LFUL006788-PA;LFUL008330-PA;LFUL006280-PA;LFUL004637-PA;LFUL011563-PA;LFUL006902-PA;LFUL016069-PA;LFUL014252-PA;LFUL015920-PA;LFUL002950-PA;LFUL006214-PA;LFUL004420-PA;LFUL001119-PA;LFUL004636-PA;LFUL000923-PA;LFUL001176-PA;LFUL003261-PA;LFUL002673-PA;LFUL004537-PA;LFUL001329-PA;LFUL008532-PA;LFUL004418-PA;LFUL015737-PA;LFUL013554-PA;LFUL011000-PA;LFUL012468-PA;LFUL010852-PA;LFUL017436-PA;LFUL013851-PA;LFUL005935-PA;LFUL000050-PA;LFUL019500-PA;LFUL009485-PA;LFUL006255-PA;LFUL018450-PA;LFUL003221-PA;LFUL006688-PA;LFUL005642-PA;LFUL000695-PA;LFUL001717-PA;LFUL002249-PA;LFUL005015-PA;LFUL014007-PA;LFUL006675-PA;LFUL011123-PA;LFUL019701-PA;LFUL014225-PA;LFUL006093-PA;LFUL007452-PA;LFUL004596-PA;LFUL007350-PA;LFUL017447-PA;LFUL008669-PA;LFUL019630-PA;LFUL010862-PA;LFUL008661-PA;LFUL002925-PA;LFUL014304-PA;LFUL015696-PA;LFUL010677-PA;LFUL018772-PA;LFUL013105-PA;LFUL012702-PA;LFUL007583-PA;LFUL009630-PA;LFUL008356-PA;LFUL007358-PA;LFUL017793-PA;LFUL014893-PA;LFUL011278-PA;LFUL002208-PA;LFUL017656-PA;LFUL001681-PA;LFUL001102-PA;LFUL018953-PA;LFUL006720-PA;LFUL012271-PA;LFUL004974-PA;LFUL006145-PA;LFUL008016-PA;LFUL017551-PA;LFUL003947-PA;LFUL012892-PA;LFUL008997-PA;LFUL019054-PA KEGG: 00592+4.2.1.17 alpha-Linolenic acid metabolism 3 LFUL012393-PA;LFUL017943-PA;LFUL018646-PA MetaCyc: PWY-7411 Phosphatidate biosynthesis (yeast) 7 LFUL017634-PA;LFUL014100-PA;LFUL002099-PA;LFUL016603-PA;LFUL016045-PA;LFUL008878-PA;LFUL009878-PA KEGG: 00350+3.7.1.2 Tyrosine metabolism 1 LFUL016091-PA MetaCyc: PWY-5123 Trans, trans-farnesyl diphosphate biosynthesis 3 LFUL011744-PA;LFUL004955-PA;LFUL008593-PA Reactome: R-HSA-9652282 Drug-mediated inhibition of ERBB2 signaling 1 LFUL010369-PA KEGG: 00480+2.3.2.2+3.4.19.13 Glutathione metabolism 6 LFUL012059-PA;LFUL012058-PA;LFUL016403-PA;LFUL016402-PA;LFUL015031-PA;LFUL003732-PA Reactome: R-HSA-9648025 EML4 and NUDC in mitotic spindle formation 51 LFUL013560-PA;LFUL002666-PA;LFUL006593-PA;LFUL007223-PA;LFUL019068-PA;LFUL005882-PA;LFUL004579-PA;LFUL009096-PA;LFUL002590-PA;LFUL015628-PA;LFUL004646-PA;LFUL010682-PA;LFUL000922-PA;LFUL015769-PA;LFUL010864-PA;LFUL009310-PA;LFUL004116-PA;LFUL014800-PA;LFUL001537-PA;LFUL004301-PA;LFUL002593-PA;LFUL005565-PA;LFUL003377-PA;LFUL009303-PA;LFUL013881-PA;LFUL009305-PA;LFUL000365-PA;LFUL011743-PA;LFUL014793-PA;LFUL013555-PA;LFUL006582-PA;LFUL010213-PA;LFUL002592-PA;LFUL012256-PA;LFUL015687-PA;LFUL014799-PA;LFUL013557-PA;LFUL009240-PA;LFUL014795-PA;LFUL016557-PA;LFUL000200-PA;LFUL015753-PA;LFUL000435-PA;LFUL008457-PA;LFUL016880-PA;LFUL013561-PA;LFUL014116-PA;LFUL010681-PA;LFUL004963-PA;LFUL014801-PA;LFUL010020-PA MetaCyc: PWY-5386 Methylglyoxal degradation I 2 LFUL015126-PA;LFUL006267-PA MetaCyc: PWY-5147 Oleate biosynthesis I (plants) 1 LFUL006083-PA Reactome: R-HSA-1614517 Sulfide oxidation to sulfate 4 LFUL013289-PA;LFUL013288-PA;LFUL008793-PA;LFUL008792-PA KEGG: 00650+4.2.1.17+1.1.1.35 Butanoate metabolism 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA Reactome: R-HSA-354192 Integrin signaling 1 LFUL000924-PA Reactome: R-HSA-388841 Costimulation by the CD28 family 1 LFUL014130-PA Reactome: R-HSA-389359 CD28 dependent Vav1 pathway 1 LFUL005324-PA KEGG: 00531+3.2.1.23 Glycosaminoglycan degradation 6 LFUL012024-PA;LFUL012258-PA;LFUL006883-PA;LFUL010553-PA;LFUL010555-PA;LFUL010554-PA KEGG: 00270+2.5.1.22 Cysteine and methionine metabolism 1 LFUL005994-PA KEGG: 00970+6.1.1.22 Aminoacyl-tRNA biosynthesis 2 LFUL009056-PA;LFUL000290-PA KEGG: 00270+3.3.1.1 Cysteine and methionine metabolism 2 LFUL018302-PA;LFUL008955-PA Reactome: R-HSA-4641263 Regulation of FZD by ubiquitination 1 LFUL004537-PA MetaCyc: PWY-4983 Nitric oxide biosynthesis II (mammals) 1 LFUL001456-PA KEGG: 00970+2.9.1.2 Aminoacyl-tRNA biosynthesis 2 LFUL019613-PA;LFUL016479-PA Reactome: R-HSA-111459 Activation of caspases through apoptosome-mediated cleavage 5 LFUL007046-PA;LFUL002198-PA;LFUL018372-PA;LFUL004784-PA;LFUL016074-PA Reactome: R-HSA-196741 Cobalamin (Cbl, vitamin B12) transport and metabolism 2 LFUL006598-PA;LFUL006260-PA Reactome: R-HSA-5675221 Negative regulation of MAPK pathway 7 LFUL002524-PA;LFUL009310-PA;LFUL005424-PA;LFUL015628-PA;LFUL014137-PA;LFUL004537-PA;LFUL011508-PA KEGG: 00983+2.7.1.21 Drug metabolism - other enzymes 1 LFUL015135-PA Reactome: R-HSA-5651801 PCNA-Dependent Long Patch Base Excision Repair 18 LFUL007277-PA;LFUL009325-PA;LFUL002760-PA;LFUL007279-PA;LFUL014494-PA;LFUL006665-PA;LFUL013345-PA;LFUL011669-PA;LFUL008688-PA;LFUL011672-PA;LFUL005720-PA;LFUL003903-PA;LFUL007960-PA;LFUL001437-PA;LFUL008002-PA;LFUL011668-PA;LFUL009126-PA;LFUL005736-PA KEGG: 00982+2.5.1.18 Drug metabolism - cytochrome P450 2 LFUL014136-PA;LFUL004307-PA KEGG: 00513+2.4.1.260 Various types of N-glycan biosynthesis 1 LFUL013830-PA Reactome: R-HSA-264870 Caspase-mediated cleavage of cytoskeletal proteins 2 LFUL016177-PA;LFUL003920-PA MetaCyc: PWY-7999 Vitamin K-epoxide cycle 2 LFUL006033-PA;LFUL001171-PA MetaCyc: PWY-7290 Escherichia coli serotype O86 O-antigen biosynthesis 3 LFUL018255-PA;LFUL004586-PA;LFUL019109-PA Reactome: R-HSA-352230 Amino acid transport across the plasma membrane 2 LFUL002403-PA;LFUL003571-PA Reactome: R-HSA-5334118 DNA methylation 3 LFUL019792-PA;LFUL003902-PA;LFUL019841-PA KEGG: 00790+3.1.3.1 Folate biosynthesis 17 LFUL010694-PA;LFUL019741-PA;LFUL014750-PA;LFUL012940-PA;LFUL015106-PA;LFUL012876-PA;LFUL012877-PA;LFUL013507-PA;LFUL010693-PA;LFUL014437-PA;LFUL014439-PA;LFUL013510-PA;LFUL013506-PA;LFUL000809-PA;LFUL018478-PA;LFUL013511-PA;LFUL018215-PA KEGG: 00760+6.3.1.5 Nicotinate and nicotinamide metabolism 1 LFUL000818-PA MetaCyc: PWY-6788 Cellulose degradation II (fungi) 1 LFUL015102-PA Reactome: R-HSA-110314 Recognition of DNA damage by PCNA-containing replication complex 21 LFUL011672-PA;LFUL005720-PA;LFUL012544-PA;LFUL004537-PA;LFUL007960-PA;LFUL012096-PA;LFUL003903-PA;LFUL001437-PA;LFUL011164-PA;LFUL008596-PA;LFUL011668-PA;LFUL005736-PA;LFUL009325-PA;LFUL007277-PA;LFUL007279-PA;LFUL014494-PA;LFUL002760-PA;LFUL006665-PA;LFUL008688-PA;LFUL013345-PA;LFUL011669-PA MetaCyc: PWY-3561 Choline biosynthesis III 1 LFUL009158-PA MetaCyc: PWY-7442 Drosopterin and aurodrosopterin biosynthesis 4 LFUL011735-PA;LFUL010398-PA;LFUL019539-PA;LFUL004602-PA Reactome: R-HSA-6783310 Fanconi Anemia Pathway 32 LFUL017965-PA;LFUL012544-PA;LFUL004537-PA;LFUL016435-PA;LFUL000716-PA;LFUL008007-PA;LFUL005736-PA;LFUL017265-PA;LFUL011502-PA;LFUL001396-PA;LFUL012429-PA;LFUL018853-PA;LFUL012559-PA;LFUL008821-PA;LFUL010557-PA;LFUL018992-PA;LFUL001092-PA;LFUL008424-PA;LFUL006792-PA;LFUL001437-PA;LFUL011501-PA;LFUL011053-PA;LFUL001675-PA;LFUL003194-PA;LFUL016730-PA;LFUL004851-PA;LFUL006135-PA;LFUL011576-PA;LFUL008425-PA;LFUL010332-PA;LFUL015323-PA;LFUL011503-PA Reactome: R-HSA-4641262 Disassembly of the destruction complex and recruitment of AXIN to the membrane 6 LFUL010552-PA;LFUL005304-PA;LFUL009310-PA;LFUL016359-PA;LFUL007844-PA;LFUL015628-PA MetaCyc: PWY-7119 Ceramide and sphingolipid recycling and degradation (yeast) 3 LFUL012329-PA;LFUL016446-PA;LFUL012328-PA Reactome: R-HSA-5358749 S37 mutants of beta-catenin aren't phosphorylated 4 LFUL010552-PA;LFUL009310-PA;LFUL007844-PA;LFUL015628-PA KEGG: 00640+6.4.1.2 Propanoate metabolism 1 LFUL005606-PA Reactome: R-HSA-2408550 Metabolism of ingested H2SeO4 and H2SeO3 into H2Se 2 LFUL019316-PA;LFUL014566-PA KEGG: 00500+2.4.1.1 Starch and sucrose metabolism 1 LFUL012958-PA MetaCyc: PWY-7288 Fatty acid beta-oxidation VII (yeast peroxisome) 2 LFUL001447-PA;LFUL001448-PA MetaCyc: PWY-7395 D-galactosamine and N-acetyl-D-galactosamine degradation 1 LFUL003224-PA Reactome: R-HSA-162699 Synthesis of dolichyl-phosphate mannose 2 LFUL007324-PA;LFUL005787-PA Reactome: R-HSA-418889 Caspase activation via Dependence Receptors in the absence of ligand 1 LFUL004784-PA KEGG: 00240+6.3.5.5 Pyrimidine metabolism 4 LFUL014039-PA;LFUL014041-PA;LFUL014042-PA;LFUL014040-PA KEGG: 00650+4.2.1.17 Butanoate metabolism 1 LFUL017943-PA KEGG: 00430+1.13.11.20 Taurine and hypotaurine metabolism 2 LFUL001559-PA;LFUL001560-PA KEGG: 00640+6.2.1.4 Propanoate metabolism 1 LFUL004029-PA Reactome: R-HSA-73817 Purine ribonucleoside monophosphate biosynthesis 10 LFUL017018-PA;LFUL017382-PA;LFUL017381-PA;LFUL013571-PA;LFUL017016-PA;LFUL019525-PA;LFUL013568-PA;LFUL001229-PA;LFUL015685-PA;LFUL015684-PA MetaCyc: PWY-6824 Justicidin B biosynthesis 7 LFUL004976-PA;LFUL019366-PA;LFUL006897-PA;LFUL006904-PA;LFUL010195-PA;LFUL010194-PA;LFUL010193-PA KEGG: 00330+2.7.2.11 Arginine and proline metabolism 1 LFUL013157-PA Reactome: R-HSA-512988 Interleukin-3, Interleukin-5 and GM-CSF signaling 1 LFUL014130-PA KEGG: 00900+1.1.1.34 Terpenoid backbone biosynthesis 1 LFUL007555-PA Reactome: R-HSA-166058 MyD88:MAL(TIRAP) cascade initiated on plasma membrane 2 LFUL013496-PA;LFUL018800-PA KEGG: 00620+1.2.4.1 Pyruvate metabolism 1 LFUL010747-PA Reactome: R-HSA-159230 Transport of the SLBP Dependant Mature mRNA 25 LFUL010864-PA;LFUL000581-PA;LFUL006358-PA;LFUL000200-PA;LFUL005157-PA;LFUL011549-PA;LFUL016880-PA;LFUL005565-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL000565-PA;LFUL002533-PA;LFUL008059-PA;LFUL016186-PA;LFUL002666-PA;LFUL003133-PA;LFUL000564-PA;LFUL005156-PA;LFUL006282-PA;LFUL015687-PA;LFUL018131-PA;LFUL009840-PA;LFUL013801-PA MetaCyc: PWY-7388 Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) 1 LFUL006083-PA KEGG: 00052+3.2.1.22 Galactose metabolism 2 LFUL015843-PA;LFUL015844-PA KEGG: 00230+3.1.3.5 Purine metabolism 2 LFUL011206-PA;LFUL011207-PA KEGG: 00051+3.1.3.11 Fructose and mannose metabolism 2 LFUL000566-PA;LFUL000567-PA KEGG: 00514+2.4.1.122 Other types of O-glycan biosynthesis 3 LFUL019109-PA;LFUL004586-PA;LFUL018255-PA Reactome: R-HSA-4719377 Defective DPM2 causes DPM2-CDG (CDG-1u) 2 LFUL005787-PA;LFUL007324-PA KEGG: 00561+3.2.1.22 Glycerolipid metabolism 2 LFUL015843-PA;LFUL015844-PA MetaCyc: PWY-7717 3-hydroxy-4-methyl-anthranilate biosynthesis I 1 LFUL015273-PA KEGG: 00020+4.2.1.2 Citrate cycle (TCA cycle) 2 LFUL017635-PA;LFUL017636-PA Reactome: R-HSA-5696394 DNA Damage Recognition in GG-NER 28 LFUL015346-PA;LFUL005659-PA;LFUL004224-PA;LFUL004537-PA;LFUL015690-PA;LFUL019465-PA;LFUL004061-PA;LFUL011164-PA;LFUL015756-PA;LFUL012951-PA;LFUL006338-PA;LFUL009763-PA;LFUL015692-PA;LFUL007336-PA;LFUL008596-PA;LFUL008306-PA;LFUL006279-PA;LFUL001333-PA;LFUL004222-PA;LFUL010109-PA;LFUL004223-PA;LFUL011081-PA;LFUL002488-PA;LFUL006876-PA;LFUL001890-PA;LFUL002836-PA;LFUL011082-PA;LFUL000305-PA KEGG: 00983+2.7.1.48 Drug metabolism - other enzymes 2 LFUL018006-PA;LFUL017794-PA MetaCyc: PWY-7854 Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered) 2 LFUL001447-PA;LFUL001448-PA Reactome: R-HSA-1655829 Regulation of cholesterol biosynthesis by SREBP (SREBF) 6 LFUL012019-PA;LFUL005822-PA;LFUL006151-PA;LFUL019075-PA;LFUL008309-PA;LFUL002083-PA Reactome: R-HSA-5658442 Regulation of RAS by GAPs 48 LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL005128-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL003914-PA;LFUL003567-PA;LFUL004335-PA;LFUL016970-PA;LFUL000664-PA;LFUL003295-PA;LFUL017243-PA;LFUL001667-PA;LFUL004537-PA;LFUL007901-PA;LFUL013396-PA;LFUL005657-PA;LFUL015255-PA;LFUL001413-PA;LFUL003296-PA;LFUL001632-PA;LFUL010331-PA;LFUL001183-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL003292-PA;LFUL013520-PA;LFUL013314-PA;LFUL005608-PA;LFUL014805-PA;LFUL001806-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL013315-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL004900-PA;LFUL013313-PA;LFUL009758-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA Reactome: R-HSA-5674135 MAP2K and MAPK activation 6 LFUL002108-PA;LFUL001132-PA;LFUL001193-PA;LFUL014137-PA;LFUL015597-PA;LFUL015596-PA Reactome: R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane 35 LFUL004364-PA;LFUL004647-PA;LFUL005590-PA;LFUL001585-PA;LFUL013557-PA;LFUL014799-PA;LFUL002531-PA;LFUL012256-PA;LFUL014617-PA;LFUL014801-PA;LFUL010020-PA;LFUL010681-PA;LFUL014795-PA;LFUL014118-PA;LFUL013561-PA;LFUL008322-PA;LFUL013894-PA;LFUL013119-PA;LFUL010682-PA;LFUL004646-PA;LFUL004648-PA;LFUL007117-PA;LFUL015328-PA;LFUL003097-PA;LFUL007698-PA;LFUL013560-PA;LFUL011881-PA;LFUL013893-PA;LFUL013555-PA;LFUL014793-PA;LFUL014800-PA;LFUL012655-PA;LFUL013117-PA;LFUL003377-PA;LFUL007699-PA KEGG: 00970+6.1.1.3 Aminoacyl-tRNA biosynthesis 4 LFUL001134-PA;LFUL003888-PA;LFUL013867-PA;LFUL001787-PA Reactome: R-HSA-71384 Ethanol oxidation 3 LFUL009238-PA;LFUL008022-PA;LFUL003019-PA KEGG: 00860+2.5.1.141 Porphyrin and chlorophyll metabolism 1 LFUL015294-PA KEGG: 00230+4.6.1.1 Purine metabolism 7 LFUL010531-PA;LFUL000754-PA;LFUL008742-PA;LFUL004880-PA;LFUL009445-PA;LFUL008741-PA;LFUL014754-PA KEGG: 00480+2.5.1.22 Glutathione metabolism 1 LFUL005994-PA KEGG: 00240+2.7.4.9 Pyrimidine metabolism 1 LFUL003582-PA Reactome: R-HSA-1483101 Synthesis of PS 2 LFUL006577-PA;LFUL002837-PA MetaCyc: PWY-6983 Threo-tetrahydrobiopterin biosynthesis 3 LFUL010398-PA;LFUL004602-PA;LFUL019539-PA KEGG: 00900+2.5.1.58 Terpenoid backbone biosynthesis 1 LFUL009288-PA KEGG: 00564+2.7.1.107 Glycerophospholipid metabolism 9 LFUL019695-PA;LFUL016206-PA;LFUL016207-PA;LFUL015114-PA;LFUL006065-PA;LFUL006554-PA;LFUL000379-PA;LFUL006064-PA;LFUL006553-PA KEGG: 00020+1.1.1.37 Citrate cycle (TCA cycle) 3 LFUL015809-PA;LFUL004113-PA;LFUL004114-PA KEGG: 00020+1.3.5.1 Citrate cycle (TCA cycle) 2 LFUL001123-PA;LFUL008263-PA Reactome: R-HSA-195253 Degradation of beta-catenin by the destruction complex 46 LFUL010441-PA;LFUL003913-PA;LFUL004013-PA;LFUL011817-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL009758-PA;LFUL004900-PA;LFUL017218-PA;LFUL017219-PA;LFUL007844-PA;LFUL015402-PA;LFUL011816-PA;LFUL015886-PA;LFUL001632-PA;LFUL001413-PA;LFUL013520-PA;LFUL010331-PA;LFUL001183-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL005608-PA;LFUL010552-PA;LFUL014805-PA;LFUL003567-PA;LFUL009310-PA;LFUL016970-PA;LFUL000664-PA;LFUL001667-PA;LFUL004537-PA;LFUL013396-PA;LFUL005657-PA;LFUL007901-PA;LFUL015255-PA;LFUL017243-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL005128-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL003914-PA;LFUL015628-PA Reactome: R-HSA-74259 Purine catabolism 7 LFUL011578-PA;LFUL014206-PA;LFUL011735-PA;LFUL011577-PA;LFUL019532-PA;LFUL015996-PA;LFUL007256-PA KEGG: 00970+6.1.1.17 Aminoacyl-tRNA biosynthesis 1 LFUL007798-PA KEGG: 00440+4.1.1.82 Phosphonate and phosphinate metabolism 1 LFUL003189-PA Reactome: R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer 14 LFUL004580-PA;LFUL010339-PA;LFUL004784-PA;LFUL000924-PA;LFUL006140-PA;LFUL005288-PA;LFUL010552-PA;LFUL010551-PA;LFUL004581-PA;LFUL006443-PA;LFUL001476-PA;LFUL001475-PA;LFUL019533-PA;LFUL007170-PA KEGG: 00770+4.2.1.9 Pantothenate and CoA biosynthesis 1 LFUL019679-PA KEGG: 00270+5.3.1.23 Cysteine and methionine metabolism 4 LFUL003374-PA;LFUL010188-PA;LFUL018466-PA;LFUL019224-PA Reactome: R-HSA-205043 NRIF signals cell death from the nucleus 6 LFUL018390-PA;LFUL003906-PA;LFUL012905-PA;LFUL008785-PA;LFUL005973-PA;LFUL004537-PA Reactome: R-HSA-5683371 Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7) 1 LFUL019677-PA KEGG: 00970+6.1.1.1 Aminoacyl-tRNA biosynthesis 2 LFUL016047-PA;LFUL005459-PA MetaCyc: PWY-3661 Glycine betaine degradation I 3 LFUL004544-PA;LFUL009609-PA;LFUL001565-PA Reactome: R-HSA-75896 Plasmalogen biosynthesis 4 LFUL018155-PA;LFUL015964-PA;LFUL015965-PA;LFUL018152-PA MetaCyc: PWY-7230 Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast) 2 LFUL002067-PA;LFUL000814-PA KEGG: 00280+4.1.3.4 Valine, leucine and isoleucine degradation 1 LFUL018576-PA Reactome: R-HSA-5663213 RHO GTPases Activate WASPs and WAVEs 20 LFUL014137-PA;LFUL015508-PA;LFUL017955-PA;LFUL006478-PA;LFUL005434-PA;LFUL013420-PA;LFUL000512-PA;LFUL010301-PA;LFUL006764-PA;LFUL005511-PA;LFUL018067-PA;LFUL002340-PA;LFUL007345-PA;LFUL009182-PA;LFUL007866-PA;LFUL018066-PA;LFUL007319-PA;LFUL005324-PA;LFUL007646-PA;LFUL007647-PA KEGG: 00340+4.2.1.49 Histidine metabolism 1 LFUL004916-PA Reactome: R-HSA-5659996 RPIA deficiency: failed conversion of R5P to RU5P 1 LFUL005639-PA KEGG: 00250+2.4.2.14 Alanine, aspartate and glutamate metabolism 1 LFUL017016-PA Reactome: R-HSA-209905 Catecholamine biosynthesis 2 LFUL004046-PA;LFUL004047-PA Reactome: R-HSA-3295583 TRP channels 12 LFUL013481-PA;LFUL016016-PA;LFUL005984-PA;LFUL005124-PA;LFUL003407-PA;LFUL000931-PA;LFUL010050-PA;LFUL005045-PA;LFUL000932-PA;LFUL013480-PA;LFUL018616-PA;LFUL005154-PA Reactome: R-HSA-162791 Attachment of GPI anchor to uPAR 7 LFUL011370-PA;LFUL001098-PA;LFUL004686-PA;LFUL013524-PA;LFUL008442-PA;LFUL008446-PA;LFUL018351-PA KEGG: 00330+3.5.1.96 Arginine and proline metabolism 1 LFUL005906-PA Reactome: R-HSA-6804756 Regulation of TP53 Activity through Phosphorylation 45 LFUL002760-PA;LFUL013749-PA;LFUL014494-PA;LFUL002498-PA;LFUL005590-PA;LFUL001585-PA;LFUL016338-PA;LFUL013345-PA;LFUL001126-PA;LFUL007836-PA;LFUL002536-PA;LFUL009882-PA;LFUL002671-PA;LFUL007096-PA;LFUL019760-PA;LFUL018855-PA;LFUL005650-PA;LFUL007162-PA;LFUL010680-PA;LFUL004051-PA;LFUL018628-PA;LFUL016703-PA;LFUL001437-PA;LFUL014965-PA;LFUL013957-PA;LFUL000689-PA;LFUL008160-PA;LFUL012191-PA;LFUL014888-PA;LFUL004632-PA;LFUL014887-PA;LFUL001415-PA;LFUL006936-PA;LFUL014459-PA;LFUL008688-PA;LFUL004537-PA;LFUL008071-PA;LFUL016337-PA;LFUL004052-PA;LFUL015240-PA;LFUL007832-PA;LFUL005736-PA;LFUL014004-PA;LFUL004631-PA;LFUL009193-PA Reactome: R-HSA-1483148 Synthesis of PG 5 LFUL014211-PA;LFUL001902-PA;LFUL009158-PA;LFUL014348-PA;LFUL010965-PA MetaCyc: PWY-7385 1,3-propanediol biosynthesis (engineered) 4 LFUL011512-PA;LFUL011354-PA;LFUL001099-PA;LFUL011355-PA Reactome: R-HSA-3000480 Scavenging by Class A Receptors 5 LFUL018059-PA;LFUL018058-PA;LFUL005945-PA;LFUL019397-PA;LFUL013535-PA Reactome: R-HSA-5693554 Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) 20 LFUL004632-PA;LFUL011482-PA;LFUL003753-PA;LFUL004270-PA;LFUL007471-PA;LFUL007096-PA;LFUL003121-PA;LFUL002671-PA;LFUL007836-PA;LFUL006936-PA;LFUL001598-PA;LFUL007979-PA;LFUL001126-PA;LFUL007832-PA;LFUL008071-PA;LFUL005650-PA;LFUL004631-PA;LFUL014965-PA;LFUL014004-PA;LFUL010680-PA MetaCyc: PWY-7221 Guanosine ribonucleotides de novo biosynthesis 13 LFUL011295-PA;LFUL008636-PA;LFUL017852-PA;LFUL006399-PA;LFUL005983-PA;LFUL017739-PA;LFUL013982-PA;LFUL010899-PA;LFUL013781-PA;LFUL004726-PA;LFUL006099-PA;LFUL005981-PA;LFUL018652-PA Reactome: R-HSA-422085 Synthesis, secretion, and deacylation of Ghrelin 6 LFUL005015-PA;LFUL015737-PA;LFUL008159-PA;LFUL006473-PA;LFUL017551-PA;LFUL006145-PA KEGG: 00510+3.2.1.106 N-Glycan biosynthesis 1 LFUL012875-PA Reactome: R-HSA-2871796 FCERI mediated MAPK activation 3 LFUL001462-PA;LFUL014137-PA;LFUL014905-PA Reactome: R-HSA-350054 Notch-HLH transcription pathway 15 LFUL006223-PA;LFUL005551-PA;LFUL003040-PA;LFUL003223-PA;LFUL018752-PA;LFUL017466-PA;LFUL017467-PA;LFUL012088-PA;LFUL017464-PA;LFUL001836-PA;LFUL016295-PA;LFUL009829-PA;LFUL017465-PA;LFUL001835-PA;LFUL016227-PA KEGG: 00930+4.2.1.17+1.1.1.35 Caprolactam degradation 3 LFUL012393-PA;LFUL017943-PA;LFUL018646-PA Reactome: R-HSA-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases 2 LFUL001602-PA;LFUL001806-PA Reactome: R-HSA-6803157 Antimicrobial peptides 23 LFUL014143-PA;LFUL012352-PA;LFUL012351-PA;LFUL008795-PA;LFUL012355-PA;LFUL008797-PA;LFUL009705-PA;LFUL006113-PA;LFUL008796-PA;LFUL009033-PA;LFUL012354-PA;LFUL012353-PA;LFUL002714-PA;LFUL008978-PA;LFUL015023-PA;LFUL018580-PA;LFUL003381-PA;LFUL019530-PA;LFUL012357-PA;LFUL012356-PA;LFUL014142-PA;LFUL008977-PA;LFUL014141-PA Reactome: R-HSA-110329 Cleavage of the damaged pyrimidine 5 LFUL016664-PA;LFUL014854-PA;LFUL017500-PA;LFUL014324-PA;LFUL013973-PA Reactome: R-HSA-1614603 Cysteine formation from homocysteine 2 LFUL001927-PA;LFUL014104-PA Reactome: R-HSA-977225 Amyloid fiber formation 7 LFUL018390-PA;LFUL004537-PA;LFUL002364-PA;LFUL008785-PA;LFUL005973-PA;LFUL008718-PA;LFUL016763-PA MetaCyc: PWY-5743 3-hydroxypropanoate cycle 9 LFUL010584-PA;LFUL004391-PA;LFUL005606-PA;LFUL012803-PA;LFUL010442-PA;LFUL017492-PA;LFUL012802-PA;LFUL009296-PA;LFUL006146-PA MetaCyc: PWY-6969 TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase) 13 LFUL012684-PA;LFUL004114-PA;LFUL001123-PA;LFUL017635-PA;LFUL006472-PA;LFUL005914-PA;LFUL016366-PA;LFUL006558-PA;LFUL017636-PA;LFUL008263-PA;LFUL004029-PA;LFUL004113-PA;LFUL015809-PA KEGG: 00281+4.1.3.4 Geraniol degradation 1 LFUL018576-PA KEGG: 00051+2.7.1.1 Fructose and mannose metabolism 3 LFUL003646-PA;LFUL004280-PA;LFUL004281-PA Reactome: R-HSA-3928665 EPH-ephrin mediated repulsion of cells 10 LFUL005973-PA;LFUL003059-PA;LFUL018390-PA;LFUL008114-PA;LFUL007853-PA;LFUL000575-PA;LFUL008785-PA;LFUL012274-PA;LFUL003906-PA;LFUL007491-PA Reactome: R-HSA-936964 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon 3 LFUL014668-PA;LFUL018695-PA;LFUL004537-PA MetaCyc: PWY-5469 Sesamin biosynthesis 7 LFUL010195-PA;LFUL006904-PA;LFUL006897-PA;LFUL010194-PA;LFUL010193-PA;LFUL019366-PA;LFUL004976-PA KEGG: 00480+3.4.11.1 Glutathione metabolism 5 LFUL003033-PA;LFUL008900-PA;LFUL014401-PA;LFUL014400-PA;LFUL014402-PA MetaCyc: PWY-7328 Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis 1 LFUL006901-PA MetaCyc: PWY-6854 Ethylene biosynthesis III (microbes) 8 LFUL011210-PA;LFUL004250-PA;LFUL013424-PA;LFUL000482-PA;LFUL002660-PA;LFUL013423-PA;LFUL013822-PA;LFUL000159-PA KEGG: 00511+3.2.1.52 Other glycan degradation 11 LFUL006590-PA;LFUL003459-PA;LFUL010431-PA;LFUL001685-PA;LFUL003458-PA;LFUL015340-PA;LFUL003460-PA;LFUL003417-PA;LFUL006704-PA;LFUL003457-PA;LFUL007928-PA MetaCyc: PWY-7559 Glutathione degradation (DUG pathway 6 LFUL015031-PA;LFUL003732-PA;LFUL016402-PA;LFUL012058-PA;LFUL012059-PA;LFUL016403-PA Reactome: R-HSA-163754 Insulin effects increased synthesis of Xylulose-5-Phosphate 1 LFUL002759-PA Reactome: R-HSA-168928 DDX58/IFIH1-mediated induction of interferon-alpha/beta 2 LFUL004537-PA;LFUL016507-PA Reactome: R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA 12 LFUL000541-PA;LFUL006413-PA;LFUL010888-PA;LFUL015271-PA;LFUL003231-PA;LFUL000163-PA;LFUL013449-PA;LFUL003227-PA;LFUL015691-PA;LFUL018238-PA;LFUL011544-PA;LFUL008668-PA Reactome: R-HSA-73980 RNA Polymerase III Transcription Termination 19 LFUL010364-PA;LFUL010060-PA;LFUL003284-PA;LFUL013037-PA;LFUL010149-PA;LFUL011471-PA;LFUL010762-PA;LFUL006931-PA;LFUL003390-PA;LFUL003911-PA;LFUL014294-PA;LFUL000388-PA;LFUL010148-PA;LFUL017259-PA;LFUL010061-PA;LFUL006932-PA;LFUL014846-PA;LFUL001373-PA;LFUL002481-PA KEGG: 00230+2.4.2.14 Purine metabolism 1 LFUL017016-PA KEGG: 00640+6.4.1.3 Propanoate metabolism 1 LFUL006146-PA MetaCyc: PWY-6946 Cholesterol degradation to androstenedione II (cholesterol dehydrogenase) 3 LFUL018646-PA;LFUL017943-PA;LFUL012393-PA MetaCyc: PWY-2161 Folate polyglutamylation 5 LFUL004544-PA;LFUL009609-PA;LFUL008282-PA;LFUL001565-PA;LFUL003915-PA MetaCyc: PWY-7799 Arg/N-end rule pathway (eukaryotic) 7 LFUL007629-PA;LFUL006276-PA;LFUL008335-PA;LFUL013955-PA;LFUL002374-PA;LFUL000406-PA;LFUL009105-PA KEGG: 00630+6.2.1.1 Glyoxylate and dicarboxylate metabolism 2 LFUL001222-PA;LFUL006868-PA KEGG: 00860+1.3.3.4 Porphyrin and chlorophyll metabolism 1 LFUL007802-PA Reactome: R-HSA-9609690 HCMV Early Events 45 LFUL006282-PA;LFUL004646-PA;LFUL007465-PA;LFUL010682-PA;LFUL002666-PA;LFUL013560-PA;LFUL006593-PA;LFUL004849-PA;LFUL009303-PA;LFUL009305-PA;LFUL013881-PA;LFUL013555-PA;LFUL009777-PA;LFUL008059-PA;LFUL014793-PA;LFUL002533-PA;LFUL014800-PA;LFUL001537-PA;LFUL010864-PA;LFUL005565-PA;LFUL003377-PA;LFUL016716-PA;LFUL015687-PA;LFUL005156-PA;LFUL013801-PA;LFUL014799-PA;LFUL013557-PA;LFUL009840-PA;LFUL018131-PA;LFUL012256-PA;LFUL016450-PA;LFUL002532-PA;LFUL014801-PA;LFUL010020-PA;LFUL010681-PA;LFUL016186-PA;LFUL000581-PA;LFUL014795-PA;LFUL016880-PA;LFUL013561-PA;LFUL016557-PA;LFUL011549-PA;LFUL006358-PA;LFUL000200-PA;LFUL005157-PA Reactome: R-HSA-68962 Activation of the pre-replicative complex 28 LFUL012083-PA;LFUL004865-PA;LFUL002563-PA;LFUL014586-PA;LFUL017711-PA;LFUL012288-PA;LFUL019733-PA;LFUL001437-PA;LFUL001174-PA;LFUL005736-PA;LFUL002734-PA;LFUL007817-PA;LFUL015871-PA;LFUL012084-PA;LFUL007277-PA;LFUL009325-PA;LFUL009032-PA;LFUL012130-PA;LFUL006063-PA;LFUL007279-PA;LFUL002178-PA;LFUL004598-PA;LFUL012409-PA;LFUL014903-PA;LFUL017714-PA;LFUL007704-PA;LFUL009340-PA;LFUL007804-PA Reactome: R-HSA-5685939 HDR through MMEJ (alt-NHEJ) 6 LFUL004631-PA;LFUL008781-PA;LFUL004632-PA;LFUL009126-PA;LFUL001126-PA;LFUL013900-PA KEGG: 05163+2.7.11.1 Human cytomegalovirus infection 50 LFUL018447-PA;LFUL002766-PA;LFUL000251-PA;LFUL001476-PA;LFUL016885-PA;LFUL018448-PA;LFUL008438-PA;LFUL006034-PA;LFUL013749-PA;LFUL004673-PA;LFUL000247-PA;LFUL004423-PA;LFUL010552-PA;LFUL000550-PA;LFUL013361-PA;LFUL010551-PA;LFUL001475-PA;LFUL004296-PA;LFUL000059-PA;LFUL009466-PA;LFUL000058-PA;LFUL017285-PA;LFUL012699-PA;LFUL016077-PA;LFUL015097-PA;LFUL006336-PA;LFUL000924-PA;LFUL016685-PA;LFUL006176-PA;LFUL000250-PA;LFUL001467-PA;LFUL015598-PA;LFUL003791-PA;LFUL015336-PA;LFUL003065-PA;LFUL019451-PA;LFUL000248-PA;LFUL012191-PA;LFUL014180-PA;LFUL008160-PA;LFUL015132-PA;LFUL001132-PA;LFUL010118-PA;LFUL000249-PA;LFUL006936-PA;LFUL014459-PA;LFUL000595-PA;LFUL014316-PA;LFUL003125-PA;LFUL005999-PA KEGG: 00650+1.3.5.1 Butanoate metabolism 2 LFUL001123-PA;LFUL008263-PA Reactome: R-HSA-3928663 EPHA-mediated growth cone collapse 1 LFUL000248-PA KEGG: 00270+2.5.1.16 Cysteine and methionine metabolism 2 LFUL005994-PA;LFUL016360-PA MetaCyc: PWY-5101 L-isoleucine biosynthesis II 1 LFUL019679-PA MetaCyc: PWY-5384 Sucrose degradation IV (sucrose phosphorylase) 1 LFUL001099-PA Reactome: R-HSA-2500257 Resolution of Sister Chromatid Cohesion 56 LFUL001864-PA;LFUL000365-PA;LFUL013881-PA;LFUL009305-PA;LFUL009303-PA;LFUL013555-PA;LFUL014793-PA;LFUL011743-PA;LFUL014800-PA;LFUL001537-PA;LFUL004116-PA;LFUL009310-PA;LFUL015769-PA;LFUL010864-PA;LFUL003377-PA;LFUL012129-PA;LFUL005565-PA;LFUL004301-PA;LFUL002593-PA;LFUL004579-PA;LFUL005882-PA;LFUL015628-PA;LFUL004646-PA;LFUL010682-PA;LFUL000922-PA;LFUL002590-PA;LFUL009096-PA;LFUL000175-PA;LFUL019068-PA;LFUL007223-PA;LFUL006593-PA;LFUL013560-PA;LFUL002666-PA;LFUL014116-PA;LFUL010020-PA;LFUL014801-PA;LFUL004963-PA;LFUL010681-PA;LFUL014795-PA;LFUL009240-PA;LFUL013561-PA;LFUL008457-PA;LFUL016880-PA;LFUL000435-PA;LFUL000200-PA;LFUL015753-PA;LFUL016557-PA;LFUL015687-PA;LFUL008627-PA;LFUL006602-PA;LFUL013557-PA;LFUL014799-PA;LFUL002592-PA;LFUL010213-PA;LFUL006582-PA;LFUL012256-PA MetaCyc: PWY-5531 3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic) 1 LFUL000195-PA KEGG: 04070+2.7.1.67 Phosphatidylinositol signaling system 3 LFUL018426-PA;LFUL018428-PA;LFUL017404-PA Reactome: R-HSA-167152 Formation of HIV elongation complex in the absence of HIV Tat 35 LFUL007672-PA;LFUL013037-PA;LFUL003284-PA;LFUL010364-PA;LFUL000565-PA;LFUL014212-PA;LFUL014608-PA;LFUL006416-PA;LFUL003797-PA;LFUL004554-PA;LFUL002212-PA;LFUL006931-PA;LFUL000398-PA;LFUL010467-PA;LFUL010456-PA;LFUL008550-PA;LFUL004885-PA;LFUL006932-PA;LFUL001415-PA;LFUL016326-PA;LFUL010620-PA;LFUL018856-PA;LFUL015513-PA;LFUL008825-PA;LFUL003397-PA;LFUL016324-PA;LFUL008342-PA;LFUL000564-PA;LFUL003393-PA;LFUL013636-PA;LFUL008827-PA;LFUL010468-PA;LFUL002536-PA;LFUL008343-PA;LFUL001373-PA KEGG: 00600+3.2.1.23 Sphingolipid metabolism 6 LFUL012024-PA;LFUL010553-PA;LFUL010555-PA;LFUL010554-PA;LFUL006883-PA;LFUL012258-PA Reactome: R-HSA-174437 Removal of the Flap Intermediate from the C-strand 7 LFUL009126-PA;LFUL007960-PA;LFUL005736-PA;LFUL005650-PA;LFUL001437-PA;LFUL006665-PA;LFUL005720-PA MetaCyc: PWY-7227 Adenosine deoxyribonucleotides de novo biosynthesis 26 LFUL008636-PA;LFUL016612-PA;LFUL013982-PA;LFUL018976-PA;LFUL004400-PA;LFUL008100-PA;LFUL019301-PA;LFUL013124-PA;LFUL017179-PA;LFUL001680-PA;LFUL004087-PA;LFUL013859-PA;LFUL005981-PA;LFUL015842-PA;LFUL011295-PA;LFUL005848-PA;LFUL008033-PA;LFUL017852-PA;LFUL019261-PA;LFUL005983-PA;LFUL017739-PA;LFUL003861-PA;LFUL006960-PA;LFUL019252-PA;LFUL014063-PA;LFUL014941-PA Reactome: R-HSA-140837 Intrinsic Pathway of Fibrin Clot Formation 3 LFUL016095-PA;LFUL010237-PA;LFUL010285-PA Reactome: R-HSA-8963684 Tyrosine catabolism 4 LFUL009335-PA;LFUL012336-PA;LFUL016091-PA;LFUL012337-PA Reactome: R-HSA-5693565 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 13 LFUL015191-PA;LFUL005424-PA;LFUL004632-PA;LFUL004537-PA;LFUL013266-PA;LFUL002340-PA;LFUL000854-PA;LFUL013202-PA;LFUL004631-PA;LFUL001126-PA;LFUL006936-PA;LFUL011470-PA;LFUL014004-PA MetaCyc: PWY-6981 Chitin biosynthesis 5 LFUL005668-PA;LFUL017830-PA;LFUL001099-PA;LFUL017831-PA;LFUL017833-PA KEGG: 00500+3.2.1.1 Starch and sucrose metabolism 2 LFUL007976-PA;LFUL007973-PA Reactome: R-HSA-5173105 O-linked glycosylation 12 LFUL014492-PA;LFUL003867-PA;LFUL009334-PA;LFUL016141-PA;LFUL003866-PA;LFUL014010-PA;LFUL015026-PA;LFUL004914-PA;LFUL016229-PA;LFUL015024-PA;LFUL017446-PA;LFUL004915-PA Reactome: R-HSA-5654727 Negative regulation of FGFR2 signaling 2 LFUL014137-PA;LFUL004537-PA Reactome: R-HSA-176034 Interactions of Tat with host cellular proteins 2 LFUL008343-PA;LFUL008342-PA Reactome: R-HSA-4085001 Sialic acid metabolism 3 LFUL005909-PA;LFUL010970-PA;LFUL001305-PA Reactome: R-HSA-210744 Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells 6 LFUL008074-PA;LFUL001836-PA;LFUL008073-PA;LFUL005551-PA;LFUL016227-PA;LFUL001835-PA KEGG: 00900+2.5.1.10+2.5.1.1 Terpenoid backbone biosynthesis 2 LFUL004955-PA;LFUL011744-PA KEGG: 04070+3.1.3.78 Phosphatidylinositol signaling system 1 LFUL014591-PA Reactome: R-HSA-390247 Beta-oxidation of very long chain fatty acids 2 LFUL000576-PA;LFUL013004-PA MetaCyc: PWY-7338 10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast) 2 LFUL001447-PA;LFUL001448-PA Reactome: R-HSA-390450 Folding of actin by CCT/TriC 9 LFUL004185-PA;LFUL000920-PA;LFUL001282-PA;LFUL007016-PA;LFUL005926-PA;LFUL001283-PA;LFUL009144-PA;LFUL017103-PA;LFUL010663-PA KEGG: 04070+2.7.7.41 Phosphatidylinositol signaling system 2 LFUL007247-PA;LFUL013010-PA KEGG: 00270+2.6.1.1 Cysteine and methionine metabolism 2 LFUL003406-PA;LFUL011379-PA KEGG: 00030+3.1.3.11 Pentose phosphate pathway 2 LFUL000567-PA;LFUL000566-PA Reactome: R-HSA-4724289 Defective ALG6 causes ALG6-CDG (CDG-1c) 1 LFUL008663-PA Reactome: R-HSA-71288 Creatine metabolism 2 LFUL005623-PA;LFUL005622-PA Reactome: R-HSA-8964038 LDL clearance 13 LFUL004825-PA;LFUL003174-PA;LFUL013535-PA;LFUL019397-PA;LFUL004259-PA;LFUL018058-PA;LFUL007491-PA;LFUL012173-PA;LFUL000575-PA;LFUL004260-PA;LFUL005945-PA;LFUL007853-PA;LFUL018059-PA MetaCyc: PWY-7268 NAD/NADP-NADH/NADPH cytosolic interconversion (yeast) 5 LFUL009108-PA;LFUL012684-PA;LFUL018313-PA;LFUL006558-PA;LFUL005193-PA MetaCyc: PWY-3861 Mannitol degradation II 1 LFUL006253-PA Reactome: R-HSA-5632987 Defective Mismatch Repair Associated With PMS2 1 LFUL016724-PA MetaCyc: PWY-7346 UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose) 1 LFUL010590-PA KEGG: 00071+4.2.1.17+1.1.1.35 Fatty acid degradation 3 LFUL012393-PA;LFUL017943-PA;LFUL018646-PA Reactome: R-HSA-177504 Retrograde neurotrophin signalling 3 LFUL000575-PA;LFUL007491-PA;LFUL007853-PA Reactome: R-HSA-3656532 TGFBR1 KD Mutants in Cancer 1 LFUL011859-PA Reactome: R-HSA-73779 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening 35 LFUL018855-PA;LFUL019760-PA;LFUL015513-PA;LFUL008825-PA;LFUL010620-PA;LFUL018856-PA;LFUL004051-PA;LFUL016703-PA;LFUL013957-PA;LFUL008827-PA;LFUL013636-PA;LFUL003393-PA;LFUL016338-PA;LFUL001373-PA;LFUL005318-PA;LFUL010468-PA;LFUL006416-PA;LFUL004052-PA;LFUL016337-PA;LFUL010364-PA;LFUL015240-PA;LFUL014212-PA;LFUL003284-PA;LFUL004050-PA;LFUL013037-PA;LFUL006931-PA;LFUL004554-PA;LFUL017944-PA;LFUL000689-PA;LFUL008550-PA;LFUL010456-PA;LFUL010467-PA;LFUL014888-PA;LFUL014887-PA;LFUL006932-PA KEGG: 00450+2.9.1.2 Selenocompound metabolism 2 LFUL016479-PA;LFUL019613-PA KEGG: 00680+3.1.2.12 Methane metabolism 1 LFUL017391-PA Reactome: R-HSA-8949215 Mitochondrial calcium ion transport 7 LFUL001454-PA;LFUL008721-PA;LFUL019602-PA;LFUL017175-PA;LFUL010326-PA;LFUL014196-PA;LFUL002365-PA Reactome: R-HSA-3878781 Glycogen storage disease type IV (GBE1) 2 LFUL014478-PA;LFUL014477-PA Reactome: R-HSA-156588 Glucuronidation 25 LFUL019799-PA;LFUL019840-PA;LFUL019782-PA;LFUL019797-PA;LFUL019800-PA;LFUL019769-PA;LFUL019794-PA;LFUL019825-PA;LFUL019798-PA;LFUL019292-PA;LFUL019814-PA;LFUL019795-PA;LFUL019838-PA;LFUL018357-PA;LFUL019837-PA;LFUL019839-PA;LFUL019775-PA;LFUL019803-PA;LFUL009359-PA;LFUL019802-PA;LFUL019819-PA;LFUL019793-PA;LFUL019801-PA;LFUL019781-PA;LFUL019796-PA KEGG: 00500+3.2.1.28 Starch and sucrose metabolism 1 LFUL017388-PA Reactome: R-HSA-75876 Synthesis of very long-chain fatty acyl-CoAs 18 LFUL015420-PA;LFUL013815-PA;LFUL010698-PA;LFUL013814-PA;LFUL012359-PA;LFUL012361-PA;LFUL002423-PA;LFUL006533-PA;LFUL013818-PA;LFUL015422-PA;LFUL004766-PA;LFUL012360-PA;LFUL013817-PA;LFUL007078-PA;LFUL013816-PA;LFUL017948-PA;LFUL001095-PA;LFUL001272-PA KEGG: 04151+2.7.11.1 PI3K-Akt signaling pathway 50 LFUL006034-PA;LFUL008438-PA;LFUL000247-PA;LFUL004673-PA;LFUL013749-PA;LFUL004423-PA;LFUL000550-PA;LFUL010552-PA;LFUL013361-PA;LFUL010551-PA;LFUL000059-PA;LFUL009466-PA;LFUL001475-PA;LFUL004296-PA;LFUL016077-PA;LFUL012699-PA;LFUL000058-PA;LFUL017285-PA;LFUL018447-PA;LFUL002766-PA;LFUL000251-PA;LFUL001476-PA;LFUL016885-PA;LFUL018448-PA;LFUL015336-PA;LFUL003065-PA;LFUL000248-PA;LFUL019451-PA;LFUL015132-PA;LFUL001132-PA;LFUL014180-PA;LFUL008160-PA;LFUL012191-PA;LFUL010118-PA;LFUL000249-PA;LFUL014459-PA;LFUL006936-PA;LFUL000595-PA;LFUL005999-PA;LFUL014316-PA;LFUL003125-PA;LFUL006336-PA;LFUL015097-PA;LFUL016685-PA;LFUL000924-PA;LFUL000250-PA;LFUL006176-PA;LFUL001467-PA;LFUL015598-PA;LFUL003791-PA MetaCyc: PWY-6978 Plastoquinol-9 biosynthesis II 2 LFUL017908-PA;LFUL017907-PA KEGG: 00500+2.4.1.11 Starch and sucrose metabolism 1 LFUL005603-PA Reactome: R-HSA-2197563 NOTCH2 intracellular domain regulates transcription 1 LFUL005551-PA KEGG: 00030+3.1.1.17 Pentose phosphate pathway 2 LFUL001189-PA;LFUL004102-PA Reactome: R-HSA-192823 Viral mRNA Translation 75 LFUL017793-PA;LFUL009630-PA;LFUL007358-PA;LFUL007583-PA;LFUL012702-PA;LFUL019054-PA;LFUL001102-PA;LFUL018953-PA;LFUL004974-PA;LFUL012271-PA;LFUL006720-PA;LFUL003947-PA;LFUL008016-PA;LFUL011278-PA;LFUL014893-PA;LFUL002208-PA;LFUL017656-PA;LFUL001681-PA;LFUL006093-PA;LFUL014225-PA;LFUL014007-PA;LFUL006675-PA;LFUL019701-PA;LFUL011123-PA;LFUL002249-PA;LFUL002925-PA;LFUL014304-PA;LFUL015696-PA;LFUL018772-PA;LFUL008661-PA;LFUL017447-PA;LFUL008669-PA;LFUL010862-PA;LFUL007452-PA;LFUL004596-PA;LFUL011000-PA;LFUL010852-PA;LFUL004418-PA;LFUL001329-PA;LFUL003261-PA;LFUL002673-PA;LFUL004537-PA;LFUL006688-PA;LFUL001717-PA;LFUL000695-PA;LFUL019500-PA;LFUL009485-PA;LFUL006255-PA;LFUL018450-PA;LFUL003221-PA;LFUL005935-PA;LFUL000050-PA;LFUL017436-PA;LFUL013851-PA;LFUL009487-PA;LFUL018996-PA;LFUL016060-PA;LFUL005171-PA;LFUL010697-PA;LFUL012852-PA;LFUL012372-PA;LFUL016059-PA;LFUL015591-PA;LFUL010275-PA;LFUL004420-PA;LFUL004636-PA;LFUL001176-PA;LFUL016069-PA;LFUL015920-PA;LFUL002950-PA;LFUL011563-PA;LFUL006902-PA;LFUL006788-PA;LFUL008330-PA;LFUL004637-PA Reactome: R-HSA-6807878 COPI-mediated anterograde transport 59 LFUL016557-PA;LFUL018560-PA;LFUL013561-PA;LFUL002675-PA;LFUL012653-PA;LFUL009164-PA;LFUL014795-PA;LFUL010681-PA;LFUL003659-PA;LFUL010020-PA;LFUL000215-PA;LFUL014801-PA;LFUL008800-PA;LFUL007212-PA;LFUL003767-PA;LFUL000842-PA;LFUL012256-PA;LFUL007953-PA;LFUL003889-PA;LFUL017228-PA;LFUL003661-PA;LFUL014799-PA;LFUL017267-PA;LFUL013557-PA;LFUL017223-PA;LFUL005184-PA;LFUL014191-PA;LFUL005085-PA;LFUL009755-PA;LFUL008799-PA;LFUL000616-PA;LFUL003377-PA;LFUL017541-PA;LFUL007845-PA;LFUL014800-PA;LFUL001537-PA;LFUL000669-PA;LFUL014793-PA;LFUL008449-PA;LFUL009649-PA;LFUL013555-PA;LFUL017615-PA;LFUL015279-PA;LFUL013560-PA;LFUL016457-PA;LFUL006593-PA;LFUL018561-PA;LFUL014707-PA;LFUL005086-PA;LFUL015280-PA;LFUL001812-PA;LFUL018558-PA;LFUL012613-PA;LFUL012651-PA;LFUL000569-PA;LFUL004646-PA;LFUL000528-PA;LFUL010682-PA;LFUL001925-PA KEGG: 00720+6.2.1.5 Carbon fixation pathways in prokaryotes 4 LFUL004029-PA;LFUL005914-PA;LFUL016366-PA;LFUL006472-PA KEGG: 00590+5.3.99.3 Arachidonic acid metabolism 1 LFUL007664-PA KEGG: 00561+2.7.1.30 Glycerolipid metabolism 1 LFUL014953-PA Reactome: R-HSA-8863795 Downregulation of ERBB2 signaling 3 LFUL010369-PA;LFUL004537-PA;LFUL005953-PA KEGG: 00562+2.7.8.11 Inositol phosphate metabolism 1 LFUL002586-PA Reactome: R-HSA-75105 Fatty acyl-CoA biosynthesis 10 LFUL013547-PA;LFUL010916-PA;LFUL006083-PA;LFUL016085-PA;LFUL010633-PA;LFUL007906-PA;LFUL007035-PA;LFUL015166-PA;LFUL016366-PA;LFUL005724-PA Reactome: R-HSA-174430 Telomere C-strand synthesis initiation 7 LFUL007804-PA;LFUL007279-PA;LFUL007277-PA;LFUL002178-PA;LFUL009325-PA;LFUL009032-PA;LFUL001174-PA Reactome: R-HSA-2142789 Ubiquinol biosynthesis 8 LFUL017907-PA;LFUL017908-PA;LFUL006594-PA;LFUL002067-PA;LFUL000814-PA;LFUL006592-PA;LFUL002194-PA;LFUL008192-PA Reactome: R-HSA-167590 Nef Mediated CD4 Down-regulation 6 LFUL007491-PA;LFUL011203-PA;LFUL011205-PA;LFUL000575-PA;LFUL011204-PA;LFUL007853-PA MetaCyc: PWY-5740 GDP-L-colitose biosynthesis 1 LFUL002512-PA MetaCyc: PWY-5392 Reductive TCA cycle II 9 LFUL004029-PA;LFUL004113-PA;LFUL015809-PA;LFUL004114-PA;LFUL017635-PA;LFUL006472-PA;LFUL016366-PA;LFUL005914-PA;LFUL017636-PA MetaCyc: PWY-7180 2-deoxy-alpha-D-ribose 1-phosphate degradation 1 LFUL012294-PA Reactome: R-HSA-445095 Interaction between L1 and Ankyrins 4 LFUL000846-PA;LFUL011441-PA;LFUL000847-PA;LFUL009649-PA Reactome: R-HSA-6785631 ERBB2 Regulates Cell Motility 1 LFUL000028-PA KEGG: 00565+3.1.1.4 Ether lipid metabolism 20 LFUL013308-PA;LFUL004585-PA;LFUL012016-PA;LFUL013307-PA;LFUL016033-PA;LFUL013311-PA;LFUL010843-PA;LFUL013309-PA;LFUL019491-PA;LFUL002722-PA;LFUL011621-PA;LFUL013310-PA;LFUL016031-PA;LFUL012592-PA;LFUL016032-PA;LFUL016881-PA;LFUL002721-PA;LFUL016034-PA;LFUL016035-PA;LFUL002720-PA MetaCyc: PWY-7226 Guanosine deoxyribonucleotides de novo biosynthesis I 26 LFUL014941-PA;LFUL014063-PA;LFUL019252-PA;LFUL017739-PA;LFUL006960-PA;LFUL003861-PA;LFUL005983-PA;LFUL017852-PA;LFUL019261-PA;LFUL008033-PA;LFUL011295-PA;LFUL015842-PA;LFUL005848-PA;LFUL013859-PA;LFUL005981-PA;LFUL004087-PA;LFUL001680-PA;LFUL013124-PA;LFUL017179-PA;LFUL019301-PA;LFUL008100-PA;LFUL018976-PA;LFUL004400-PA;LFUL013982-PA;LFUL016612-PA;LFUL008636-PA Reactome: R-HSA-5627117 RHO GTPases Activate ROCKs 1 LFUL000248-PA Reactome: R-HSA-3560801 Defective B3GAT3 causes JDSSDHD 4 LFUL005814-PA;LFUL009642-PA;LFUL002623-PA;LFUL002624-PA MetaCyc: PWY-8055 Palmitoyl ethanolamide biosynthesis 10 LFUL011019-PA;LFUL009878-PA;LFUL008878-PA;LFUL017634-PA;LFUL014100-PA;LFUL002099-PA;LFUL005920-PA;LFUL011020-PA;LFUL016045-PA;LFUL016603-PA Reactome: R-HSA-9665245 Resistance of ERBB2 KD mutants to tesevatinib 1 LFUL010369-PA KEGG: 00240+2.1.1.45 Pyrimidine metabolism 2 LFUL002259-PA;LFUL002258-PA MetaCyc: PWY-6124 Inosine-5'-phosphate biosynthesis II 4 LFUL015685-PA;LFUL015684-PA;LFUL001229-PA;LFUL017018-PA KEGG: 00521+2.7.1.1 Streptomycin biosynthesis 3 LFUL003646-PA;LFUL004280-PA;LFUL004281-PA MetaCyc: PWY-7936 Psilocybin biosynthesis 12 LFUL017515-PA;LFUL017514-PA;LFUL011077-PA;LFUL003119-PA;LFUL001435-PA;LFUL008577-PA;LFUL016788-PA;LFUL017513-PA;LFUL002420-PA;LFUL014877-PA;LFUL016065-PA;LFUL006589-PA Reactome: R-HSA-8850843 Phosphate bond hydrolysis by NTPDase proteins 2 LFUL000275-PA;LFUL008761-PA KEGG: 00362+4.2.1.17 Benzoate degradation 1 LFUL017943-PA Reactome: R-HSA-2467813 Separation of Sister Chromatids 107 LFUL004579-PA;LFUL006784-PA;LFUL006381-PA;LFUL005882-PA;LFUL000922-PA;LFUL004646-PA;LFUL010682-PA;LFUL003914-PA;LFUL009096-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL007223-PA;LFUL006593-PA;LFUL002666-PA;LFUL001864-PA;LFUL000365-PA;LFUL015255-PA;LFUL004537-PA;LFUL007901-PA;LFUL011394-PA;LFUL014800-PA;LFUL003567-PA;LFUL009310-PA;LFUL015769-PA;LFUL006691-PA;LFUL004301-PA;LFUL000664-PA;LFUL013953-PA;LFUL015687-PA;LFUL013557-PA;LFUL008627-PA;LFUL001632-PA;LFUL002592-PA;LFUL006582-PA;LFUL011826-PA;LFUL002279-PA;LFUL010213-PA;LFUL012256-PA;LFUL013520-PA;LFUL004085-PA;LFUL011827-PA;LFUL018065-PA;LFUL010331-PA;LFUL014116-PA;LFUL004900-PA;LFUL017218-PA;LFUL004963-PA;LFUL015402-PA;LFUL010681-PA;LFUL014795-PA;LFUL009240-PA;LFUL013561-PA;LFUL009774-PA;LFUL000200-PA;LFUL016557-PA;LFUL013254-PA;LFUL009759-PA;LFUL015628-PA;LFUL002590-PA;LFUL000175-PA;LFUL005128-PA;LFUL019068-PA;LFUL008983-PA;LFUL001285-PA;LFUL013560-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL013555-PA;LFUL001667-PA;LFUL013396-PA;LFUL005657-PA;LFUL017243-PA;LFUL014793-PA;LFUL011743-PA;LFUL001537-PA;LFUL004116-PA;LFUL010864-PA;LFUL012129-PA;LFUL003377-PA;LFUL005565-PA;LFUL002593-PA;LFUL016970-PA;LFUL000448-PA;LFUL005608-PA;LFUL006602-PA;LFUL014799-PA;LFUL014805-PA;LFUL001413-PA;LFUL017608-PA;LFUL010327-PA;LFUL001183-PA;LFUL009758-PA;LFUL017219-PA;LFUL014801-PA;LFUL010020-PA;LFUL011816-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL007684-PA;LFUL008457-PA;LFUL016880-PA;LFUL015753-PA;LFUL000435-PA;LFUL013277-PA MetaCyc: PWY-5849 Menaquinol-6 biosynthesis 2 LFUL006594-PA;LFUL006592-PA KEGG: 00190+3.6.1.1 Oxidative phosphorylation 3 LFUL004778-PA;LFUL004386-PA;LFUL007408-PA KEGG: 00564+2.7.8.11 Glycerophospholipid metabolism 1 LFUL002586-PA Reactome: R-HSA-1253288 Downregulation of ERBB4 signaling 1 LFUL004537-PA Reactome: R-HSA-8941333 RUNX2 regulates genes involved in differentiation of myeloid cells 4 LFUL009513-PA;LFUL009515-PA;LFUL009514-PA;LFUL009516-PA Reactome: R-HSA-1251985 Nuclear signaling by ERBB4 5 LFUL009003-PA;LFUL008785-PA;LFUL005973-PA;LFUL003906-PA;LFUL018390-PA Reactome: R-HSA-4086398 Ca2+ pathway 23 LFUL000620-PA;LFUL018125-PA;LFUL009246-PA;LFUL004232-PA;LFUL015532-PA;LFUL015531-PA;LFUL008435-PA;LFUL012255-PA;LFUL016516-PA;LFUL006196-PA;LFUL007947-PA;LFUL014374-PA;LFUL009249-PA;LFUL006745-PA;LFUL005993-PA;LFUL003893-PA;LFUL017104-PA;LFUL019785-PA;LFUL005454-PA;LFUL006660-PA;LFUL019805-PA;LFUL000640-PA;LFUL018127-PA MetaCyc: PWY-5856 Ubiquinol-9 biosynthesis (prokaryotic) 4 LFUL017907-PA;LFUL017908-PA;LFUL000814-PA;LFUL002067-PA Reactome: R-HSA-606279 Deposition of new CENPA-containing nucleosomes at the centromere 8 LFUL011198-PA;LFUL000365-PA;LFUL011199-PA;LFUL010213-PA;LFUL006582-PA;LFUL011201-PA;LFUL007223-PA;LFUL006279-PA Reactome: R-HSA-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol 1 LFUL001420-PA KEGG: 00511+3.2.1.96 Other glycan degradation 1 LFUL008556-PA Reactome: R-HSA-6803205 TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain 4 LFUL016785-PA;LFUL017209-PA;LFUL017992-PA;LFUL008605-PA Reactome: R-HSA-3359463 Defective CUBN causes hereditary megaloblastic anemia 1 1 LFUL006260-PA MetaCyc: PWY-7094 Fatty acid salvage 3 LFUL018646-PA;LFUL017943-PA;LFUL012393-PA KEGG: 00510+2.4.1.258 N-Glycan biosynthesis 1 LFUL008581-PA Reactome: R-HSA-5545483 Defective Mismatch Repair Associated With MLH1 1 LFUL016724-PA KEGG: 00030+1.1.1.49 Pentose phosphate pathway 1 LFUL018313-PA Reactome: R-HSA-73930 Abasic sugar-phosphate removal via the single-nucleotide replacement pathway 1 LFUL008002-PA KEGG: 00500+5.3.1.9 Starch and sucrose metabolism 1 LFUL001099-PA KEGG: 00230+2.7.4.8 Purine metabolism 6 LFUL010899-PA;LFUL018652-PA;LFUL006099-PA;LFUL004726-PA;LFUL006399-PA;LFUL013781-PA MetaCyc: PWY-7210 Pyrimidine deoxyribonucleotides biosynthesis from CTP 31 LFUL013859-PA;LFUL003582-PA;LFUL005981-PA;LFUL002258-PA;LFUL004087-PA;LFUL019301-PA;LFUL008100-PA;LFUL001680-PA;LFUL013124-PA;LFUL017179-PA;LFUL016612-PA;LFUL002917-PA;LFUL005425-PA;LFUL004400-PA;LFUL018976-PA;LFUL013982-PA;LFUL008636-PA;LFUL014941-PA;LFUL019252-PA;LFUL002259-PA;LFUL014063-PA;LFUL005983-PA;LFUL017852-PA;LFUL019261-PA;LFUL006960-PA;LFUL017739-PA;LFUL003861-PA;LFUL005848-PA;LFUL015842-PA;LFUL011295-PA;LFUL008033-PA MetaCyc: PWYG-321 2 LFUL006146-PA;LFUL006083-PA Reactome: R-HSA-201451 Signaling by BMP 1 LFUL002941-PA Reactome: R-HSA-5693616 Presynaptic phase of homologous DNA pairing and strand exchange 23 LFUL005650-PA;LFUL008071-PA;LFUL007832-PA;LFUL014004-PA;LFUL010680-PA;LFUL005736-PA;LFUL004631-PA;LFUL001437-PA;LFUL014965-PA;LFUL018628-PA;LFUL014494-PA;LFUL002760-PA;LFUL011482-PA;LFUL004632-PA;LFUL012191-PA;LFUL007836-PA;LFUL006936-PA;LFUL008688-PA;LFUL007979-PA;LFUL013345-PA;LFUL001126-PA;LFUL007096-PA;LFUL002671-PA Reactome: R-HSA-5576892 Phase 0 - rapid depolarisation 11 LFUL000846-PA;LFUL015922-PA;LFUL011901-PA;LFUL013366-PA;LFUL002885-PA;LFUL011441-PA;LFUL011903-PA;LFUL014649-PA;LFUL014650-PA;LFUL011579-PA;LFUL000847-PA Reactome: R-HSA-6809371 Formation of the cornified envelope 7 LFUL009944-PA;LFUL009945-PA;LFUL009941-PA;LFUL009946-PA;LFUL001116-PA;LFUL009947-PA;LFUL009942-PA KEGG: 00190+1.3.5.1 Oxidative phosphorylation 2 LFUL008263-PA;LFUL001123-PA Reactome: R-HSA-1482798 Acyl chain remodeling of CL 1 LFUL017943-PA Reactome: R-HSA-416993 Trafficking of GluR2-containing AMPA receptors 5 LFUL001925-PA;LFUL007853-PA;LFUL007151-PA;LFUL000575-PA;LFUL007491-PA KEGG: 00562+3.1.4.11 Inositol phosphate metabolism 8 LFUL015148-PA;LFUL001462-PA;LFUL001109-PA;LFUL006196-PA;LFUL014147-PA;LFUL006197-PA;LFUL016455-PA;LFUL001461-PA Reactome: R-HSA-167827 The proton buffering model 1 LFUL014201-PA MetaCyc: PWY-6839 2-aminoethylphosphonate biosynthesis 1 LFUL003189-PA Reactome: R-HSA-5663220 RHO GTPases Activate Formins 57 LFUL005882-PA;LFUL004579-PA;LFUL003795-PA;LFUL009096-PA;LFUL002590-PA;LFUL004646-PA;LFUL015628-PA;LFUL010682-PA;LFUL000922-PA;LFUL019507-PA;LFUL016359-PA;LFUL006593-PA;LFUL002666-PA;LFUL013560-PA;LFUL019508-PA;LFUL007223-PA;LFUL019068-PA;LFUL013881-PA;LFUL009305-PA;LFUL009303-PA;LFUL000365-PA;LFUL005324-PA;LFUL014793-PA;LFUL011743-PA;LFUL013555-PA;LFUL009310-PA;LFUL010864-PA;LFUL015769-PA;LFUL001537-PA;LFUL014800-PA;LFUL004116-PA;LFUL004301-PA;LFUL002593-PA;LFUL003377-PA;LFUL005565-PA;LFUL015687-PA;LFUL004533-PA;LFUL013557-PA;LFUL014799-PA;LFUL010213-PA;LFUL006582-PA;LFUL002592-PA;LFUL012256-PA;LFUL014116-PA;LFUL004963-PA;LFUL010681-PA;LFUL010020-PA;LFUL014801-PA;LFUL014795-PA;LFUL009240-PA;LFUL000200-PA;LFUL015753-PA;LFUL000435-PA;LFUL016557-PA;LFUL013561-PA;LFUL008457-PA;LFUL016880-PA Reactome: R-HSA-162658 Golgi Cisternae Pericentriolar Stack Reorganization 4 LFUL010745-PA;LFUL018098-PA;LFUL014707-PA;LFUL014137-PA Reactome: R-HSA-380320 Recruitment of NuMA to mitotic centrosomes 44 LFUL004301-PA;LFUL015517-PA;LFUL015876-PA;LFUL003377-PA;LFUL017541-PA;LFUL010291-PA;LFUL014800-PA;LFUL014793-PA;LFUL013555-PA;LFUL013560-PA;LFUL014621-PA;LFUL004344-PA;LFUL002327-PA;LFUL009096-PA;LFUL018303-PA;LFUL004646-PA;LFUL010682-PA;LFUL004460-PA;LFUL014798-PA;LFUL013561-PA;LFUL015311-PA;LFUL007649-PA;LFUL002675-PA;LFUL012132-PA;LFUL014795-PA;LFUL010681-PA;LFUL011516-PA;LFUL010020-PA;LFUL014801-PA;LFUL010399-PA;LFUL001762-PA;LFUL009638-PA;LFUL010789-PA;LFUL012510-PA;LFUL014797-PA;LFUL006471-PA;LFUL009757-PA;LFUL012256-PA;LFUL010290-PA;LFUL003889-PA;LFUL014799-PA;LFUL010041-PA;LFUL013557-PA;LFUL000416-PA MetaCyc: PWY-6142 Gluconeogenesis II (Methanobacterium thermoautotrophicum) 10 LFUL011512-PA;LFUL010584-PA;LFUL001099-PA;LFUL004391-PA;LFUL001192-PA;LFUL005591-PA;LFUL012802-PA;LFUL012803-PA;LFUL011112-PA;LFUL017492-PA KEGG: 00450+6.1.1.10 Selenocompound metabolism 2 LFUL014405-PA;LFUL004311-PA Reactome: R-HSA-4793952 Defective MGAT2 causes MGAT2-CDG (CDG-2a) 1 LFUL018519-PA KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35 Fatty acid degradation 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA KEGG: 00940+1.11.1.7 Phenylpropanoid biosynthesis 7 LFUL019366-PA;LFUL004976-PA;LFUL010195-PA;LFUL006897-PA;LFUL006904-PA;LFUL010193-PA;LFUL010194-PA KEGG: 00600+3.1.4.12 Sphingolipid metabolism 1 LFUL009479-PA Reactome: R-HSA-5654732 Negative regulation of FGFR3 signaling 2 LFUL004537-PA;LFUL014137-PA KEGG: 00030+2.7.1.15 Pentose phosphate pathway 1 LFUL014002-PA Reactome: R-HSA-203754 NOSIP mediated eNOS trafficking 1 LFUL003805-PA Reactome: R-HSA-9648895 Response of EIF2AK1 (HRI) to heme deficiency 4 LFUL006181-PA;LFUL002211-PA;LFUL008294-PA;LFUL005206-PA MetaCyc: PWY-6596 Adenosine nucleotides degradation I 3 LFUL011206-PA;LFUL011207-PA;LFUL000108-PA MetaCyc: PWY-7883 Anhydromuropeptides recycling II 11 LFUL001685-PA;LFUL003459-PA;LFUL010431-PA;LFUL003458-PA;LFUL006590-PA;LFUL003457-PA;LFUL007928-PA;LFUL006704-PA;LFUL003417-PA;LFUL003460-PA;LFUL015340-PA Reactome: R-HSA-210500 Glutamate Neurotransmitter Release Cycle 3 LFUL003072-PA;LFUL010866-PA;LFUL010868-PA KEGG: 00230+1.7.1.7 Purine metabolism 1 LFUL017374-PA Reactome: R-HSA-191650 Regulation of gap junction activity 1 LFUL007567-PA Reactome: R-HSA-3359462 Defective AMN causes hereditary megaloblastic anemia 1 1 LFUL006260-PA Reactome: R-HSA-3134963 DEx/H-box helicases activate type I IFN and inflammatory cytokines production 1 LFUL018800-PA KEGG: 00020+6.2.1.5 Citrate cycle (TCA cycle) 4 LFUL006472-PA;LFUL004029-PA;LFUL016366-PA;LFUL005914-PA KEGG: 00250+6.3.4.4 Alanine, aspartate and glutamate metabolism 3 LFUL017381-PA;LFUL017382-PA;LFUL019525-PA MetaCyc: PWY-7839 Lacto-series glycosphingolipids biosynthesis 1 LFUL014857-PA KEGG: 00860+6.1.1.17 Porphyrin and chlorophyll metabolism 1 LFUL007798-PA Reactome: R-HSA-426117 Cation-coupled Chloride cotransporters 9 LFUL007271-PA;LFUL007270-PA;LFUL012199-PA;LFUL002019-PA;LFUL000053-PA;LFUL002023-PA;LFUL007342-PA;LFUL012406-PA;LFUL012407-PA Reactome: R-HSA-196108 Pregnenolone biosynthesis 4 LFUL003519-PA;LFUL000649-PA;LFUL007911-PA;LFUL000648-PA Reactome: R-HSA-167826 The fatty acid cycling model 1 LFUL014201-PA KEGG: 00330+4.1.1.50 Arginine and proline metabolism 1 LFUL011332-PA MetaCyc: PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis 12 LFUL015148-PA;LFUL017404-PA;LFUL001462-PA;LFUL018426-PA;LFUL001461-PA;LFUL016455-PA;LFUL002586-PA;LFUL014147-PA;LFUL018428-PA;LFUL006197-PA;LFUL006196-PA;LFUL001109-PA KEGG: 00760+2.3.1.286 Nicotinate and nicotinamide metabolism 6 LFUL008149-PA;LFUL016890-PA;LFUL006676-PA;LFUL015326-PA;LFUL004757-PA;LFUL001905-PA Reactome: R-HSA-114608 Platelet degranulation 12 LFUL006738-PA;LFUL015596-PA;LFUL016095-PA;LFUL001787-PA;LFUL006737-PA;LFUL015267-PA;LFUL001330-PA;LFUL002973-PA;LFUL010285-PA;LFUL014108-PA;LFUL015597-PA;LFUL014109-PA MetaCyc: PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) 4 LFUL019642-PA;LFUL014713-PA;LFUL007957-PA;LFUL009747-PA MetaCyc: PWY-5188 Tetrapyrrole biosynthesis I (from glutamate) 4 LFUL005083-PA;LFUL011432-PA;LFUL007835-PA;LFUL007798-PA KEGG: 00564+3.1.1.4+3.1.1.5 Glycerophospholipid metabolism 11 LFUL016034-PA;LFUL019491-PA;LFUL016035-PA;LFUL002720-PA;LFUL002722-PA;LFUL016031-PA;LFUL016033-PA;LFUL010843-PA;LFUL012592-PA;LFUL016032-PA;LFUL002721-PA Reactome: R-HSA-2564830 Cytosolic iron-sulfur cluster assembly 7 LFUL003151-PA;LFUL003150-PA;LFUL014847-PA;LFUL016908-PA;LFUL003149-PA;LFUL001160-PA;LFUL014212-PA KEGG: 00983+2.4.2.4 Drug metabolism - other enzymes 1 LFUL005855-PA MetaCyc: PWY-7199 Pyrimidine deoxyribonucleosides salvage 4 LFUL002259-PA;LFUL011652-PA;LFUL015135-PA;LFUL002258-PA KEGG: 00280+6.4.1.3 Valine, leucine and isoleucine degradation 1 LFUL006146-PA MetaCyc: PWY-7736 Stellatic acid biosynthesis 2 LFUL004955-PA;LFUL011744-PA MetaCyc: PWY-7727 Docosahexaenoate biosynthesis IV (4-desaturase, mammals) 2 LFUL001272-PA;LFUL010698-PA MetaCyc: PWY-6853 Ethylene biosynthesis II (microbes) 1 LFUL012268-PA Reactome: R-HSA-3214815 HDACs deacetylate histones 9 LFUL012088-PA;LFUL014619-PA;LFUL016295-PA;LFUL003226-PA;LFUL009328-PA;LFUL003040-PA;LFUL013705-PA;LFUL009777-PA;LFUL002061-PA Reactome: R-HSA-202433 Generation of second messenger molecules 3 LFUL011853-PA;LFUL001462-PA;LFUL007345-PA MetaCyc: PWY-5971 Palmitate biosynthesis II (bacteria and plant cytoplasm) 1 LFUL006083-PA Reactome: R-HSA-5654733 Negative regulation of FGFR4 signaling 2 LFUL014137-PA;LFUL004537-PA MetaCyc: PWY-7726 (4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase) 7 LFUL001448-PA;LFUL001447-PA;LFUL017943-PA;LFUL012393-PA;LFUL010698-PA;LFUL001272-PA;LFUL018646-PA Reactome: R-HSA-111463 SMAC (DIABLO) binds to IAPs 5 LFUL007046-PA;LFUL002198-PA;LFUL016074-PA;LFUL004784-PA;LFUL018372-PA Reactome: R-HSA-8955332 Carboxyterminal post-translational modifications of tubulin 28 LFUL014800-PA;LFUL014795-PA;LFUL014258-PA;LFUL008546-PA;LFUL003377-PA;LFUL013561-PA;LFUL001741-PA;LFUL012006-PA;LFUL010971-PA;LFUL014793-PA;LFUL010681-PA;LFUL010490-PA;LFUL013555-PA;LFUL014801-PA;LFUL010020-PA;LFUL003948-PA;LFUL002295-PA;LFUL013560-PA;LFUL012256-PA;LFUL006528-PA;LFUL016808-PA;LFUL010682-PA;LFUL004646-PA;LFUL013557-PA;LFUL018451-PA;LFUL014799-PA;LFUL013152-PA;LFUL011570-PA MetaCyc: PWY-7181 Pyrimidine deoxyribonucleosides degradation 2 LFUL011652-PA;LFUL005855-PA Reactome: R-HSA-211981 Xenobiotics 8 LFUL013284-PA;LFUL019092-PA;LFUL018961-PA;LFUL018496-PA;LFUL016762-PA;LFUL007894-PA;LFUL019543-PA;LFUL008509-PA Reactome: R-HSA-1566948 Elastic fibre formation 1 LFUL004008-PA Reactome: R-HSA-432722 Golgi Associated Vesicle Biogenesis 12 LFUL005721-PA;LFUL006677-PA;LFUL013821-PA;LFUL010059-PA;LFUL019133-PA;LFUL018714-PA;LFUL004754-PA;LFUL018711-PA;LFUL014967-PA;LFUL017722-PA;LFUL009119-PA;LFUL009309-PA KEGG: 00910+6.3.1.2 Nitrogen metabolism 1 LFUL012349-PA Reactome: R-HSA-419037 NCAM1 interactions 3 LFUL009021-PA;LFUL013366-PA;LFUL019569-PA MetaCyc: PWY-7587 Oleate biosynthesis III (cyanobacteria) 7 LFUL016045-PA;LFUL016603-PA;LFUL008878-PA;LFUL009878-PA;LFUL002099-PA;LFUL017634-PA;LFUL014100-PA Reactome: R-HSA-110331 Cleavage of the damaged purine 2 LFUL014324-PA;LFUL004576-PA MetaCyc: PWY-8067 Methylphosphonate biosynthesis 1 LFUL003189-PA Reactome: R-HSA-77595 Processing of Intronless Pre-mRNAs 14 LFUL001011-PA;LFUL017088-PA;LFUL000565-PA;LFUL017085-PA;LFUL011758-PA;LFUL000564-PA;LFUL004759-PA;LFUL017090-PA;LFUL011823-PA;LFUL017089-PA;LFUL002514-PA;LFUL001010-PA;LFUL015919-PA;LFUL004758-PA Reactome: R-HSA-2408522 Selenoamino acid metabolism 12 LFUL003447-PA;LFUL013267-PA;LFUL004441-PA;LFUL003958-PA;LFUL003522-PA;LFUL014891-PA;LFUL000216-PA;LFUL003004-PA;LFUL010289-PA;LFUL001438-PA;LFUL004311-PA;LFUL015627-PA KEGG: 00534+5.1.3.17 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 1 LFUL004864-PA MetaCyc: PWY-5789 3-hydroxypropanoate/4-hydroxybutanate cycle 12 LFUL006146-PA;LFUL012393-PA;LFUL009296-PA;LFUL012802-PA;LFUL017492-PA;LFUL010442-PA;LFUL018646-PA;LFUL012803-PA;LFUL017943-PA;LFUL005606-PA;LFUL010584-PA;LFUL004391-PA Reactome: R-HSA-70171 Glycolysis 13 LFUL011512-PA;LFUL005858-PA;LFUL011354-PA;LFUL005591-PA;LFUL001192-PA;LFUL001099-PA;LFUL004281-PA;LFUL004280-PA;LFUL008549-PA;LFUL015710-PA;LFUL011112-PA;LFUL011355-PA;LFUL003646-PA Reactome: R-HSA-9018519 Estrogen-dependent gene expression 37 LFUL006745-PA;LFUL010620-PA;LFUL018856-PA;LFUL008825-PA;LFUL009514-PA;LFUL014303-PA;LFUL009515-PA;LFUL008342-PA;LFUL009516-PA;LFUL006602-PA;LFUL005454-PA;LFUL008827-PA;LFUL008073-PA;LFUL005318-PA;LFUL008343-PA;LFUL001373-PA;LFUL008074-PA;LFUL009513-PA;LFUL013037-PA;LFUL003284-PA;LFUL010364-PA;LFUL003829-PA;LFUL015532-PA;LFUL015531-PA;LFUL012546-PA;LFUL014299-PA;LFUL004232-PA;LFUL018367-PA;LFUL014004-PA;LFUL006931-PA;LFUL019805-PA;LFUL008550-PA;LFUL006660-PA;LFUL006932-PA;LFUL014905-PA;LFUL019785-PA;LFUL000175-PA Reactome: R-HSA-6811436 COPI-independent Golgi-to-ER retrograde traffic 34 LFUL005184-PA;LFUL003889-PA;LFUL014799-PA;LFUL013557-PA;LFUL018221-PA;LFUL007212-PA;LFUL012256-PA;LFUL010681-PA;LFUL010020-PA;LFUL014801-PA;LFUL002675-PA;LFUL011413-PA;LFUL014795-PA;LFUL016557-PA;LFUL003969-PA;LFUL018220-PA;LFUL013561-PA;LFUL004646-PA;LFUL017271-PA;LFUL010682-PA;LFUL013560-PA;LFUL006593-PA;LFUL016457-PA;LFUL000669-PA;LFUL014793-PA;LFUL011411-PA;LFUL013555-PA;LFUL017541-PA;LFUL014800-PA;LFUL001537-PA;LFUL018219-PA;LFUL004301-PA;LFUL009755-PA;LFUL003377-PA Reactome: R-HSA-5423646 Aflatoxin activation and detoxification 2 LFUL000874-PA;LFUL007710-PA Reactome: R-HSA-74749 Signal attenuation 1 LFUL014137-PA KEGG: 00281+4.2.1.17+1.1.1.35 Geraniol degradation 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA Reactome: R-HSA-69202 Cyclin E associated events during G1/S transition 8 LFUL010468-PA;LFUL000101-PA;LFUL014016-PA;LFUL010456-PA;LFUL010467-PA;LFUL014149-PA;LFUL009289-PA;LFUL006416-PA Reactome: R-HSA-425986 Sodium/Proton exchangers 7 LFUL005557-PA;LFUL005559-PA;LFUL005558-PA;LFUL000605-PA;LFUL009519-PA;LFUL009518-PA;LFUL000604-PA MetaCyc: PWY-7863 Roseoflavin biosynthesis 1 LFUL005319-PA MetaCyc: PWY-7102 Bisabolene biosynthesis (engineered) 3 LFUL004955-PA;LFUL011744-PA;LFUL008593-PA KEGG: 00562+5.3.1.1 Inositol phosphate metabolism 1 LFUL005591-PA Reactome: R-HSA-4086400 PCP/CE pathway 5 LFUL016359-PA;LFUL005667-PA;LFUL004540-PA;LFUL005666-PA;LFUL004541-PA MetaCyc: PWY-5189 Tetrapyrrole biosynthesis II (from glycine) 4 LFUL005083-PA;LFUL011432-PA;LFUL007835-PA;LFUL017816-PA Reactome: R-HSA-1433557 Signaling by SCF-KIT 3 LFUL012191-PA;LFUL014233-PA;LFUL014130-PA MetaCyc: PWY-6842 Glutathione-mediated detoxification II 10 LFUL013724-PA;LFUL013723-PA;LFUL016403-PA;LFUL012059-PA;LFUL004307-PA;LFUL012058-PA;LFUL016402-PA;LFUL014136-PA;LFUL003732-PA;LFUL015031-PA KEGG: 00020+6.2.1.4 Citrate cycle (TCA cycle) 1 LFUL004029-PA KEGG: 00860+2.5.1.61 Porphyrin and chlorophyll metabolism 1 LFUL005083-PA Reactome: R-HSA-9630221 Defective NTHL1 substrate processing 1 LFUL014324-PA Reactome: R-HSA-2173791 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 1 LFUL004537-PA Reactome: R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry 8 LFUL010456-PA;LFUL014149-PA;LFUL010467-PA;LFUL009289-PA;LFUL006416-PA;LFUL010468-PA;LFUL000101-PA;LFUL014016-PA KEGG: 00250+6.3.1.2 Alanine, aspartate and glutamate metabolism 1 LFUL012349-PA KEGG: 00510+1.3.1.94 N-Glycan biosynthesis 1 LFUL009957-PA Reactome: R-HSA-5687128 MAPK6/MAPK4 signaling 52 LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL006745-PA;LFUL009758-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA;LFUL014805-PA;LFUL005454-PA;LFUL005608-PA;LFUL000664-PA;LFUL016970-PA;LFUL015531-PA;LFUL015532-PA;LFUL003567-PA;LFUL004116-PA;LFUL004232-PA;LFUL017243-PA;LFUL001667-PA;LFUL004537-PA;LFUL005657-PA;LFUL013396-PA;LFUL007901-PA;LFUL015255-PA;LFUL005324-PA;LFUL005128-PA;LFUL019785-PA;LFUL014905-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL006660-PA;LFUL003914-PA;LFUL009759-PA;LFUL006784-PA;LFUL019805-PA;LFUL014180-PA;LFUL013254-PA Reactome: R-HSA-5083635 Defective B3GALTL causes Peters-plus syndrome (PpS) 26 LFUL008471-PA;LFUL014662-PA;LFUL000153-PA;LFUL008066-PA;LFUL005670-PA;LFUL000326-PA;LFUL008146-PA;LFUL011651-PA;LFUL005250-PA;LFUL000325-PA;LFUL008065-PA;LFUL006833-PA;LFUL005249-PA;LFUL008472-PA;LFUL006830-PA;LFUL005671-PA;LFUL011650-PA;LFUL013848-PA;LFUL014661-PA;LFUL004425-PA;LFUL015588-PA;LFUL010351-PA;LFUL005672-PA;LFUL006829-PA;LFUL006832-PA;LFUL016899-PA Reactome: R-HSA-4641265 Repression of WNT target genes 4 LFUL000579-PA;LFUL008435-PA;LFUL005993-PA;LFUL016876-PA Reactome: R-HSA-1170546 Prolactin receptor signaling 1 LFUL015886-PA Reactome: R-HSA-5578998 Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) 1 LFUL011543-PA Reactome: R-HSA-1237112 Methionine salvage pathway 8 LFUL004262-PA;LFUL001636-PA;LFUL004263-PA;LFUL006786-PA;LFUL006774-PA;LFUL005625-PA;LFUL010188-PA;LFUL006775-PA Reactome: R-HSA-917729 Endosomal Sorting Complex Required For Transport (ESCRT) 13 LFUL012304-PA;LFUL008608-PA;LFUL004537-PA;LFUL002956-PA;LFUL003450-PA;LFUL001539-PA;LFUL006398-PA;LFUL013808-PA;LFUL010679-PA;LFUL010282-PA;LFUL012732-PA;LFUL012973-PA;LFUL002957-PA KEGG: 00790+2.10.1.1 Folate biosynthesis 2 LFUL009927-PA;LFUL009929-PA Reactome: R-HSA-933541 TRAF6 mediated IRF7 activation 3 LFUL008073-PA;LFUL008074-PA;LFUL018695-PA MetaCyc: PWY-7222 Guanosine deoxyribonucleotides de novo biosynthesis II 26 LFUL016612-PA;LFUL004400-PA;LFUL018976-PA;LFUL013982-PA;LFUL008636-PA;LFUL005981-PA;LFUL013859-PA;LFUL004087-PA;LFUL019301-PA;LFUL008100-PA;LFUL001680-PA;LFUL013124-PA;LFUL017179-PA;LFUL005983-PA;LFUL017852-PA;LFUL019261-PA;LFUL003861-PA;LFUL017739-PA;LFUL006960-PA;LFUL015842-PA;LFUL005848-PA;LFUL011295-PA;LFUL008033-PA;LFUL014941-PA;LFUL019252-PA;LFUL014063-PA Reactome: R-HSA-8934593 Regulation of RUNX1 Expression and Activity 12 LFUL005454-PA;LFUL006660-PA;LFUL009516-PA;LFUL009514-PA;LFUL019805-PA;LFUL006745-PA;LFUL009513-PA;LFUL004232-PA;LFUL009515-PA;LFUL015532-PA;LFUL015531-PA;LFUL019785-PA Reactome: R-HSA-159236 Transport of Mature mRNA derived from an Intron-Containing Transcript 48 LFUL016186-PA;LFUL003765-PA;LFUL014785-PA;LFUL002532-PA;LFUL005950-PA;LFUL006358-PA;LFUL000200-PA;LFUL005157-PA;LFUL011549-PA;LFUL012680-PA;LFUL016786-PA;LFUL016880-PA;LFUL010423-PA;LFUL000581-PA;LFUL018131-PA;LFUL011279-PA;LFUL009840-PA;LFUL013801-PA;LFUL005156-PA;LFUL000564-PA;LFUL015687-PA;LFUL004782-PA;LFUL006595-PA;LFUL005901-PA;LFUL005875-PA;LFUL001187-PA;LFUL002533-PA;LFUL008059-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL002148-PA;LFUL016879-PA;LFUL000565-PA;LFUL014935-PA;LFUL005565-PA;LFUL002379-PA;LFUL010864-PA;LFUL016230-PA;LFUL018008-PA;LFUL008524-PA;LFUL005874-PA;LFUL006282-PA;LFUL009571-PA;LFUL002666-PA;LFUL003763-PA;LFUL001669-PA;LFUL005876-PA MetaCyc: PWY-5532 Nucleoside and nucleotide degradation (archaea) 3 LFUL011577-PA;LFUL006725-PA;LFUL011578-PA KEGG: 00230+3.6.1.6 Purine metabolism 1 LFUL002917-PA KEGG: 00770+2.7.1.33 Pantothenate and CoA biosynthesis 2 LFUL012867-PA;LFUL016820-PA Reactome: R-HSA-166208 mTORC1-mediated signalling 19 LFUL004637-PA;LFUL006140-PA;LFUL004571-PA;LFUL002108-PA;LFUL009573-PA;LFUL006345-PA;LFUL016269-PA;LFUL001475-PA;LFUL004636-PA;LFUL018435-PA;LFUL010339-PA;LFUL001193-PA;LFUL011021-PA;LFUL004570-PA;LFUL009057-PA;LFUL016180-PA;LFUL012362-PA;LFUL001476-PA;LFUL006443-PA MetaCyc: PWY-6435 4-hydroxybenzoate biosynthesis III (plants) 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA Reactome: R-HSA-1483152 Hydrolysis of LPE 2 LFUL013371-PA;LFUL013370-PA MetaCyc: PWY-7902 Glucosylglycerol biosynthesis 2 LFUL016131-PA;LFUL016130-PA Reactome: R-HSA-1679131 Trafficking and processing of endosomal TLR 1 LFUL007858-PA Reactome: R-HSA-5576894 Phase 1 - inactivation of fast Na+ channels 2 LFUL008930-PA;LFUL008928-PA Reactome: R-HSA-8849473 PTK6 Expression 2 LFUL014616-PA;LFUL012371-PA Reactome: R-HSA-6802948 Signaling by high-kinase activity BRAF mutants 4 LFUL015596-PA;LFUL015597-PA;LFUL014137-PA;LFUL001132-PA Reactome: R-HSA-1855167 Synthesis of pyrophosphates in the cytosol 5 LFUL000654-PA;LFUL000653-PA;LFUL019642-PA;LFUL014713-PA;LFUL007957-PA Reactome: R-HSA-165054 Rev-mediated nuclear export of HIV RNA 24 LFUL005156-PA;LFUL006282-PA;LFUL015687-PA;LFUL009840-PA;LFUL018131-PA;LFUL013801-PA;LFUL002666-PA;LFUL009303-PA;LFUL013881-PA;LFUL002532-PA;LFUL009305-PA;LFUL016186-PA;LFUL008059-PA;LFUL002533-PA;LFUL010864-PA;LFUL000581-PA;LFUL004116-PA;LFUL011549-PA;LFUL000200-PA;LFUL012019-PA;LFUL005157-PA;LFUL006358-PA;LFUL005565-PA;LFUL016880-PA Reactome: R-HSA-4090294 SUMOylation of intracellular receptors 6 LFUL002701-PA;LFUL001143-PA;LFUL013730-PA;LFUL002401-PA;LFUL001142-PA;LFUL001141-PA MetaCyc: PWY-4302 Aerobic respiration III (alternative oxidase pathway) 2 LFUL008263-PA;LFUL001123-PA KEGG: 00533+2.4.1.68 Glycosaminoglycan biosynthesis - keratan sulfate 1 LFUL011017-PA Reactome: R-HSA-5693548 Sensing of DNA Double Strand Breaks 5 LFUL004632-PA;LFUL004631-PA;LFUL014004-PA;LFUL006936-PA;LFUL001126-PA KEGG: 00900+2.7.7.60 Terpenoid backbone biosynthesis 1 LFUL006367-PA KEGG: 00520+4.2.1.47 Amino sugar and nucleotide sugar metabolism 1 LFUL002512-PA KEGG: 00380+1.13.11.11 Tryptophan metabolism 3 LFUL019496-PA;LFUL016193-PA;LFUL016192-PA Reactome: R-HSA-5660862 Defective SLC7A7 causes lysinuric protein intolerance (LPI) 1 LFUL003571-PA KEGG: 00240+2.7.1.48 Pyrimidine metabolism 2 LFUL017794-PA;LFUL018006-PA MetaCyc: PWY-5514 UDP-N-acetyl-D-galactosamine biosynthesis II 3 LFUL001099-PA;LFUL005858-PA;LFUL009918-PA KEGG: 00510+2.4.1.131 N-Glycan biosynthesis 1 LFUL011924-PA KEGG: 00052+2.7.7.12 Galactose metabolism 1 LFUL015403-PA Reactome: R-HSA-3371511 HSF1 activation 3 LFUL001437-PA;LFUL005006-PA;LFUL005736-PA KEGG: 00790+4.2.1.96 Folate biosynthesis 1 LFUL000107-PA MetaCyc: PWY-5737 (5R)-carbapenem carboxylate biosynthesis 3 LFUL014993-PA;LFUL014994-PA;LFUL011522-PA KEGG: 00062+3.1.2.22 Fatty acid elongation 1 LFUL010633-PA KEGG: 00010+2.3.1.12 Glycolysis / Gluconeogenesis 1 LFUL008261-PA KEGG: 04070+2.7.4.24+2.7.4.21 Phosphatidylinositol signaling system 2 LFUL000653-PA;LFUL000654-PA MetaCyc: PWY-5912 2'-deoxymugineic acid phytosiderophore biosynthesis 1 LFUL012283-PA MetaCyc: PWY-7049 Icosapentaenoate biosynthesis II (6-desaturase, mammals) 2 LFUL010698-PA;LFUL001272-PA KEGG: 00270+1.1.1.27 Cysteine and methionine metabolism 1 LFUL015394-PA KEGG: 00514+2.4.1.255 Other types of O-glycan biosynthesis 2 LFUL012676-PA;LFUL012677-PA Reactome: R-HSA-975574 Reactions specific to the hybrid N-glycan synthesis pathway 1 LFUL006201-PA MetaCyc: PWY-8052 2-arachidonoylglycerol biosynthesis 11 LFUL011020-PA;LFUL005920-PA;LFUL015148-PA;LFUL016455-PA;LFUL001109-PA;LFUL006197-PA;LFUL014147-PA;LFUL006196-PA;LFUL001461-PA;LFUL001462-PA;LFUL011019-PA Reactome: R-HSA-525793 Myogenesis 7 LFUL016977-PA;LFUL003462-PA;LFUL002340-PA;LFUL018141-PA;LFUL017925-PA;LFUL004533-PA;LFUL005324-PA KEGG: 00410+4.2.1.17 beta-Alanine metabolism 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA MetaCyc: PWY-6901 Superpathway of glucose and xylose degradation 5 LFUL008549-PA;LFUL015710-PA;LFUL011112-PA;LFUL001192-PA;LFUL015394-PA Reactome: R-HSA-71032 Propionyl-CoA catabolism 1 LFUL006146-PA Reactome: R-HSA-167246 Tat-mediated elongation of the HIV-1 transcript 33 LFUL004554-PA;LFUL002212-PA;LFUL006931-PA;LFUL000398-PA;LFUL010364-PA;LFUL014212-PA;LFUL007672-PA;LFUL013037-PA;LFUL003284-PA;LFUL003797-PA;LFUL014608-PA;LFUL006416-PA;LFUL006932-PA;LFUL016326-PA;LFUL001415-PA;LFUL010456-PA;LFUL010467-PA;LFUL004885-PA;LFUL008550-PA;LFUL016324-PA;LFUL008342-PA;LFUL015513-PA;LFUL008825-PA;LFUL018856-PA;LFUL010620-PA;LFUL003397-PA;LFUL010468-PA;LFUL001373-PA;LFUL008343-PA;LFUL002536-PA;LFUL008827-PA;LFUL013636-PA;LFUL003393-PA Reactome: R-HSA-5358565 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) 8 LFUL007836-PA;LFUL000900-PA;LFUL005736-PA;LFUL016724-PA;LFUL001437-PA;LFUL006665-PA;LFUL007960-PA;LFUL005720-PA Reactome: R-HSA-194840 Rho GTPase cycle 52 LFUL001301-PA;LFUL008496-PA;LFUL003790-PA;LFUL006286-PA;LFUL005633-PA;LFUL007978-PA;LFUL002046-PA;LFUL001155-PA;LFUL002755-PA;LFUL019649-PA;LFUL002246-PA;LFUL018420-PA;LFUL008382-PA;LFUL014579-PA;LFUL014180-PA;LFUL002048-PA;LFUL009483-PA;LFUL018708-PA;LFUL013756-PA;LFUL003791-PA;LFUL004437-PA;LFUL001466-PA;LFUL007723-PA;LFUL013612-PA;LFUL018422-PA;LFUL008439-PA;LFUL000806-PA;LFUL013454-PA;LFUL001912-PA;LFUL005324-PA;LFUL013611-PA;LFUL001156-PA;LFUL003730-PA;LFUL004562-PA;LFUL002386-PA;LFUL005322-PA;LFUL008398-PA;LFUL001877-PA;LFUL004002-PA;LFUL013046-PA;LFUL016932-PA;LFUL019644-PA;LFUL018421-PA;LFUL011214-PA;LFUL001303-PA;LFUL007977-PA;LFUL010619-PA;LFUL005183-PA;LFUL004990-PA;LFUL017019-PA;LFUL008198-PA;LFUL006470-PA KEGG: 00410+4.1.1.9 beta-Alanine metabolism 1 LFUL013004-PA Reactome: R-HSA-500657 Presynaptic function of Kainate receptors 6 LFUL012255-PA;LFUL000620-PA;LFUL006196-PA;LFUL003893-PA;LFUL017104-PA;LFUL000640-PA Reactome: R-HSA-2514859 Inactivation, recovery and regulation of the phototransduction cascade 5 LFUL004930-PA;LFUL000797-PA;LFUL004928-PA;LFUL006276-PA;LFUL009288-PA MetaCyc: PWY-5154 L-arginine biosynthesis III (via N-acetyl-L-citrulline) 4 LFUL014042-PA;LFUL014040-PA;LFUL014039-PA;LFUL014041-PA Reactome: R-HSA-165158 Activation of AKT2 2 LFUL006181-PA;LFUL000924-PA MetaCyc: PWY-3385 Choline biosynthesis I 1 LFUL001619-PA Reactome: R-HSA-5673000 RAF activation 4 LFUL011508-PA;LFUL002885-PA;LFUL015628-PA;LFUL009310-PA KEGG: 00051+5.3.1.5 Fructose and mannose metabolism 1 LFUL014343-PA Reactome: R-HSA-8939245 RUNX1 regulates transcription of genes involved in BCR signaling 4 LFUL009516-PA;LFUL009514-PA;LFUL009515-PA;LFUL009513-PA Reactome: R-HSA-1474228 Degradation of the extracellular matrix 9 LFUL003564-PA;LFUL005509-PA;LFUL006439-PA;LFUL008785-PA;LFUL010053-PA;LFUL004620-PA;LFUL012080-PA;LFUL003566-PA;LFUL008752-PA MetaCyc: PWY-6722 Candicidin biosynthesis 3 LFUL010442-PA;LFUL005606-PA;LFUL009296-PA KEGG: 00513+2.4.1.142 Various types of N-glycan biosynthesis 1 LFUL007469-PA Reactome: R-HSA-69273 Cyclin A/B1/B2 associated events during G2/M transition 8 LFUL008405-PA;LFUL008385-PA;LFUL006416-PA;LFUL010456-PA;LFUL010467-PA;LFUL007962-PA;LFUL004116-PA;LFUL010468-PA KEGG: 00480+6.3.2.3 Glutathione metabolism 1 LFUL003123-PA KEGG: 00710+5.3.1.1 Carbon fixation in photosynthetic organisms 1 LFUL005591-PA Reactome: R-HSA-6782135 Dual incision in TC-NER 49 LFUL006416-PA;LFUL003758-PA;LFUL004537-PA;LFUL003903-PA;LFUL007960-PA;LFUL003284-PA;LFUL013037-PA;LFUL013502-PA;LFUL011672-PA;LFUL014212-PA;LFUL010364-PA;LFUL008596-PA;LFUL011668-PA;LFUL006931-PA;LFUL005736-PA;LFUL011164-PA;LFUL004554-PA;LFUL007279-PA;LFUL008550-PA;LFUL010467-PA;LFUL009325-PA;LFUL010456-PA;LFUL007277-PA;LFUL019536-PA;LFUL008688-PA;LFUL006932-PA;LFUL000317-PA;LFUL000593-PA;LFUL000117-PA;LFUL014365-PA;LFUL007187-PA;LFUL010620-PA;LFUL005720-PA;LFUL015513-PA;LFUL001437-PA;LFUL009780-PA;LFUL003393-PA;LFUL014494-PA;LFUL002760-PA;LFUL013636-PA;LFUL000113-PA;LFUL006135-PA;LFUL013345-PA;LFUL006986-PA;LFUL001373-PA;LFUL008562-PA;LFUL011669-PA;LFUL010468-PA;LFUL006665-PA MetaCyc: PWY-5663 Erythro-tetrahydrobiopterin biosynthesis I 3 LFUL010398-PA;LFUL019539-PA;LFUL004602-PA MetaCyc: PWY-7437 Protein O-[N-acetyl]-glucosylation 3 LFUL012677-PA;LFUL012676-PA;LFUL017539-PA KEGG: 00970+6.1.1.7 Aminoacyl-tRNA biosynthesis 2 LFUL015523-PA;LFUL010797-PA Reactome: R-HSA-211976 Endogenous sterols 4 LFUL008509-PA;LFUL007911-PA;LFUL003519-PA;LFUL013284-PA Reactome: R-HSA-190861 Gap junction assembly 15 LFUL014793-PA;LFUL010681-PA;LFUL013557-PA;LFUL004646-PA;LFUL010682-PA;LFUL013555-PA;LFUL014799-PA;LFUL010020-PA;LFUL014801-PA;LFUL013560-PA;LFUL012256-PA;LFUL003377-PA;LFUL013561-PA;LFUL014795-PA;LFUL014800-PA Reactome: R-HSA-9613829 Chaperone Mediated Autophagy 2 LFUL000787-PA;LFUL004537-PA MetaCyc: PWY-8004 Entner-Doudoroff pathway I 7 LFUL018313-PA;LFUL015710-PA;LFUL009918-PA;LFUL008549-PA;LFUL001192-PA;LFUL008386-PA;LFUL011112-PA MetaCyc: PWY-6829 Trna methylation (yeast) 9 LFUL006754-PA;LFUL007169-PA;LFUL002182-PA;LFUL003742-PA;LFUL011055-PA;LFUL002928-PA;LFUL011125-PA;LFUL005873-PA;LFUL006400-PA KEGG: 00051+4.2.1.68 Fructose and mannose metabolism 1 LFUL012781-PA MetaCyc: PWY-5265 Peptidoglycan biosynthesis II (staphylococci) 2 LFUL009636-PA;LFUL006200-PA KEGG: 00520+3.5.1.25 Amino sugar and nucleotide sugar metabolism 1 LFUL003224-PA MetaCyc: PWY-1801 Formaldehyde oxidation II (glutathione-dependent) 1 LFUL017391-PA Reactome: R-HSA-983189 Kinesins 48 LFUL004949-PA;LFUL012318-PA;LFUL000076-PA;LFUL002040-PA;LFUL012256-PA;LFUL019746-PA;LFUL007048-PA;LFUL001638-PA;LFUL014209-PA;LFUL013557-PA;LFUL014799-PA;LFUL014210-PA;LFUL014795-PA;LFUL007390-PA;LFUL013561-PA;LFUL008322-PA;LFUL013045-PA;LFUL005812-PA;LFUL003722-PA;LFUL012319-PA;LFUL005850-PA;LFUL010681-PA;LFUL005851-PA;LFUL019594-PA;LFUL010020-PA;LFUL014801-PA;LFUL018877-PA;LFUL007047-PA;LFUL007367-PA;LFUL013560-PA;LFUL011528-PA;LFUL005811-PA;LFUL005915-PA;LFUL000696-PA;LFUL004646-PA;LFUL010682-PA;LFUL004639-PA;LFUL014800-PA;LFUL009670-PA;LFUL003377-PA;LFUL012286-PA;LFUL007592-PA;LFUL014793-PA;LFUL008594-PA;LFUL013555-PA;LFUL014915-PA;LFUL007049-PA;LFUL002129-PA Reactome: R-HSA-189483 Heme degradation 2 LFUL005036-PA;LFUL019455-PA Reactome: R-HSA-69183 Processive synthesis on the lagging strand 7 LFUL005720-PA;LFUL006665-PA;LFUL002178-PA;LFUL009032-PA;LFUL001174-PA;LFUL007960-PA;LFUL007804-PA Reactome: R-HSA-376176 Signaling by ROBO receptors 1 LFUL011853-PA Reactome: R-HSA-9022538 Loss of MECP2 binding ability to 5mC-DNA 1 LFUL008336-PA MetaCyc: PWY-7769 Phosalacine biosynthesis 1 LFUL003189-PA KEGG: 00564+3.1.4.4 Glycerophospholipid metabolism 1 LFUL009158-PA Reactome: R-HSA-5619061 Defective SLC33A1 causes spastic paraplegia 42 (SPG42) 1 LFUL011999-PA MetaCyc: PWY-7356 Thiamine salvage IV (yeast) 1 LFUL006365-PA KEGG: 00500+3.6.1.9 Starch and sucrose metabolism 2 LFUL014206-PA;LFUL000002-PA KEGG: 00600+3.5.1.23 Sphingolipid metabolism 3 LFUL016446-PA;LFUL012328-PA;LFUL012329-PA Reactome: R-HSA-442720 CREB1 phosphorylation through the activation of Adenylate Cyclase 1 LFUL015154-PA KEGG: 00520+1.1.1.22 Amino sugar and nucleotide sugar metabolism 1 LFUL010590-PA Reactome: R-HSA-76066 RNA Polymerase III Transcription Initiation From Type 2 Promoter 24 LFUL014846-PA;LFUL001373-PA;LFUL010063-PA;LFUL002481-PA;LFUL010061-PA;LFUL006932-PA;LFUL011294-PA;LFUL001093-PA;LFUL014294-PA;LFUL003911-PA;LFUL017259-PA;LFUL000388-PA;LFUL005061-PA;LFUL006931-PA;LFUL015757-PA;LFUL003390-PA;LFUL006422-PA;LFUL015504-PA;LFUL011471-PA;LFUL010762-PA;LFUL010364-PA;LFUL013037-PA;LFUL003284-PA;LFUL010060-PA Reactome: R-HSA-216083 Integrin cell surface interactions 26 LFUL019380-PA;LFUL008964-PA;LFUL012003-PA;LFUL013097-PA;LFUL007502-PA;LFUL008962-PA;LFUL001504-PA;LFUL009021-PA;LFUL012568-PA;LFUL003427-PA;LFUL012570-PA;LFUL007501-PA;LFUL012569-PA;LFUL008963-PA;LFUL012002-PA;LFUL019566-PA;LFUL017506-PA;LFUL003428-PA;LFUL017505-PA;LFUL001503-PA;LFUL012571-PA;LFUL010054-PA;LFUL017504-PA;LFUL001505-PA;LFUL008965-PA;LFUL019569-PA Reactome: R-HSA-8964011 HDL clearance 1 LFUL006260-PA MetaCyc: PWY-6922 L-Ndelta-acetylornithine biosynthesis 5 LFUL014993-PA;LFUL014392-PA;LFUL011522-PA;LFUL013157-PA;LFUL014994-PA Reactome: R-HSA-1296072 Voltage gated Potassium channels 19 LFUL008592-PA;LFUL000491-PA;LFUL011751-PA;LFUL010322-PA;LFUL008929-PA;LFUL011607-PA;LFUL011646-PA;LFUL008928-PA;LFUL011605-PA;LFUL019604-PA;LFUL001142-PA;LFUL011604-PA;LFUL000490-PA;LFUL002824-PA;LFUL014682-PA;LFUL008930-PA;LFUL009140-PA;LFUL006730-PA;LFUL010323-PA Reactome: R-HSA-5617472 Activation of anterior HOX genes in hindbrain development during early embryogenesis 19 LFUL010269-PA;LFUL007465-PA;LFUL008550-PA;LFUL001373-PA;LFUL006098-PA;LFUL008073-PA;LFUL014905-PA;LFUL006932-PA;LFUL011069-PA;LFUL011253-PA;LFUL010364-PA;LFUL010620-PA;LFUL003284-PA;LFUL010270-PA;LFUL004849-PA;LFUL013037-PA;LFUL008074-PA;LFUL006931-PA;LFUL016716-PA MetaCyc: PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis 5 LFUL015744-PA;LFUL011055-PA;LFUL002182-PA;LFUL011912-PA;LFUL003742-PA Reactome: R-HSA-983695 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers 2 LFUL009246-PA;LFUL009249-PA Reactome: R-HSA-69473 G2/M DNA damage checkpoint 25 LFUL001126-PA;LFUL013345-PA;LFUL008688-PA;LFUL007836-PA;LFUL006936-PA;LFUL011470-PA;LFUL002671-PA;LFUL007096-PA;LFUL002760-PA;LFUL014494-PA;LFUL012191-PA;LFUL004632-PA;LFUL005736-PA;LFUL010680-PA;LFUL014004-PA;LFUL018628-PA;LFUL013202-PA;LFUL014965-PA;LFUL004631-PA;LFUL001437-PA;LFUL005650-PA;LFUL008071-PA;LFUL013266-PA;LFUL007832-PA;LFUL015191-PA Reactome: R-HSA-8937144 Aryl hydrocarbon receptor signalling 2 LFUL008509-PA;LFUL013284-PA Reactome: R-HSA-446199 Synthesis of Dolichyl-phosphate 5 LFUL011884-PA;LFUL009957-PA;LFUL006417-PA;LFUL011043-PA;LFUL013534-PA MetaCyc: PWY-2201 Folate transformations I 6 LFUL003915-PA;LFUL015994-PA;LFUL001565-PA;LFUL009609-PA;LFUL014192-PA;LFUL004544-PA MetaCyc: PWY-5491 Diethylphosphate degradation 17 LFUL013507-PA;LFUL012877-PA;LFUL012940-PA;LFUL014750-PA;LFUL012876-PA;LFUL015106-PA;LFUL019741-PA;LFUL010694-PA;LFUL000809-PA;LFUL018478-PA;LFUL013506-PA;LFUL018215-PA;LFUL013511-PA;LFUL014439-PA;LFUL013510-PA;LFUL010693-PA;LFUL014437-PA Reactome: R-HSA-4655427 SUMOylation of DNA methylation proteins 3 LFUL019841-PA;LFUL019792-PA;LFUL003902-PA MetaCyc: PWY-7817 Type I lipoteichoic acid biosynthesis (S. aureus) 14 LFUL006065-PA;LFUL014211-PA;LFUL013010-PA;LFUL008565-PA;LFUL000379-PA;LFUL006554-PA;LFUL006553-PA;LFUL006064-PA;LFUL016206-PA;LFUL019695-PA;LFUL001902-PA;LFUL016207-PA;LFUL015114-PA;LFUL007247-PA Reactome: R-HSA-3560783 Defective B4GALT7 causes EDS, progeroid type 4 LFUL005814-PA;LFUL009642-PA;LFUL002623-PA;LFUL002624-PA MetaCyc: PWY-5122 Geranyl diphosphate biosynthesis 2 LFUL011744-PA;LFUL004955-PA Reactome: R-HSA-2151201 Transcriptional activation of mitochondrial biogenesis 18 LFUL011677-PA;LFUL019623-PA;LFUL007046-PA;LFUL018284-PA;LFUL016629-PA;LFUL012911-PA;LFUL000811-PA;LFUL018367-PA;LFUL016890-PA;LFUL010028-PA;LFUL002198-PA;LFUL000159-PA;LFUL017915-PA;LFUL008149-PA;LFUL003799-PA;LFUL015835-PA;LFUL008872-PA;LFUL016356-PA MetaCyc: PWY-6433 Hydroxylated fatty acid biosynthesis (plants) 18 LFUL001095-PA;LFUL017948-PA;LFUL001272-PA;LFUL012360-PA;LFUL015422-PA;LFUL013818-PA;LFUL004766-PA;LFUL013816-PA;LFUL007078-PA;LFUL013817-PA;LFUL002423-PA;LFUL012361-PA;LFUL006533-PA;LFUL013815-PA;LFUL015420-PA;LFUL012359-PA;LFUL013814-PA;LFUL010698-PA MetaCyc: PWY-7118 Chitin degradation to ethanol 2 LFUL001222-PA;LFUL006868-PA Reactome: R-HSA-442982 Ras activation upon Ca2+ influx through NMDA receptor 5 LFUL010847-PA;LFUL002885-PA;LFUL018841-PA;LFUL010848-PA;LFUL009416-PA Reactome: R-HSA-9635465 Suppression of apoptosis 1 LFUL014137-PA MetaCyc: PWY-8088 Dipicolinate biosynthesis 1 LFUL009128-PA Reactome: R-HSA-73943 Reversal of alkylation damage by DNA dioxygenases 1 LFUL000385-PA Reactome: R-HSA-8939247 RUNX1 regulates transcription of genes involved in interleukin signaling 4 LFUL009513-PA;LFUL009515-PA;LFUL009514-PA;LFUL009516-PA Reactome: R-HSA-77348 Beta oxidation of octanoyl-CoA to hexanoyl-CoA 1 LFUL017943-PA KEGG: 00680+6.2.1.1 Methane metabolism 2 LFUL006868-PA;LFUL001222-PA Reactome: R-HSA-1660516 Synthesis of PIPs at the early endosome membrane 7 LFUL018428-PA;LFUL012051-PA;LFUL017404-PA;LFUL012052-PA;LFUL004611-PA;LFUL018426-PA;LFUL002733-PA KEGG: 00643+3.7.1.2 Styrene degradation 1 LFUL016091-PA Reactome: R-HSA-2219530 Constitutive Signaling by Aberrant PI3K in Cancer 1 LFUL014130-PA KEGG: 00970+2.1.2.9 Aminoacyl-tRNA biosynthesis 1 LFUL000378-PA MetaCyc: PWY-6708 Ubiquinol-8 biosynthesis (prokaryotic) 4 LFUL002067-PA;LFUL017907-PA;LFUL017908-PA;LFUL000814-PA KEGG: 00240+3.6.1.9 Pyrimidine metabolism 2 LFUL014206-PA;LFUL000002-PA Reactome: R-HSA-174362 Transport and synthesis of PAPS 2 LFUL019316-PA;LFUL014566-PA MetaCyc: PWY-6385 Peptidoglycan biosynthesis III (mycobacteria) 1 LFUL009636-PA MetaCyc: PWY-6168 Flavin biosynthesis III (fungi) 1 LFUL005319-PA KEGG: 00332+2.7.2.11 Carbapenem biosynthesis 1 LFUL013157-PA Reactome: R-HSA-2132295 MHC class II antigen presentation 54 LFUL016113-PA;LFUL016457-PA;LFUL006593-PA;LFUL013560-PA;LFUL016112-PA;LFUL007858-PA;LFUL007491-PA;LFUL006151-PA;LFUL003917-PA;LFUL004419-PA;LFUL000429-PA;LFUL004646-PA;LFUL010682-PA;LFUL017541-PA;LFUL004639-PA;LFUL003142-PA;LFUL014800-PA;LFUL001537-PA;LFUL007860-PA;LFUL017040-PA;LFUL009755-PA;LFUL003377-PA;LFUL013881-PA;LFUL016850-PA;LFUL012286-PA;LFUL005822-PA;LFUL014793-PA;LFUL000669-PA;LFUL013555-PA;LFUL004421-PA;LFUL000693-PA;LFUL012256-PA;LFUL007212-PA;LFUL007853-PA;LFUL005184-PA;LFUL001638-PA;LFUL003889-PA;LFUL013557-PA;LFUL014799-PA;LFUL000575-PA;LFUL002675-PA;LFUL014795-PA;LFUL007861-PA;LFUL016557-PA;LFUL013561-PA;LFUL013045-PA;LFUL008322-PA;LFUL016327-PA;LFUL010970-PA;LFUL019459-PA;LFUL007859-PA;LFUL010681-PA;LFUL014801-PA;LFUL010020-PA KEGG: 00730+3.1.3.2 Thiamine metabolism 3 LFUL017688-PA;LFUL016357-PA;LFUL001985-PA KEGG: 00980+2.5.1.18 Metabolism of xenobiotics by cytochrome P450 2 LFUL004307-PA;LFUL014136-PA MetaCyc: PWY-7721 Methyl phomopsenoate biosynthesis 2 LFUL004955-PA;LFUL011744-PA Reactome: R-HSA-1971475 A tetrasaccharide linker sequence is required for GAG synthesis 8 LFUL005514-PA;LFUL009642-PA;LFUL005513-PA;LFUL005814-PA;LFUL018892-PA;LFUL002623-PA;LFUL002624-PA;LFUL018893-PA KEGG: 00010+5.1.3.15 Glycolysis / Gluconeogenesis 1 LFUL008360-PA MetaCyc: PWY-7818 Type IV lipoteichoic acid biosynthesis (S. pneumoniae) 1 LFUL001619-PA Reactome: R-HSA-162588 Budding and maturation of HIV virion 8 LFUL002957-PA;LFUL012973-PA;LFUL010679-PA;LFUL001539-PA;LFUL003450-PA;LFUL002956-PA;LFUL004537-PA;LFUL012304-PA MetaCyc: PWY-6992 1,5-anhydrofructose degradation 4 LFUL006253-PA;LFUL019543-PA;LFUL001099-PA;LFUL007894-PA Reactome: R-HSA-5579006 Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) 1 LFUL003123-PA Reactome: R-HSA-450408 AUF1 (hnRNP D0) binds and destabilizes mRNA 41 LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL009758-PA;LFUL001183-PA;LFUL010331-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL013520-PA;LFUL001413-PA;LFUL018435-PA;LFUL001632-PA;LFUL014805-PA;LFUL005608-PA;LFUL000664-PA;LFUL016970-PA;LFUL003567-PA;LFUL017243-PA;LFUL013396-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL005657-PA;LFUL015255-PA;LFUL005128-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL003914-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA Reactome: R-HSA-456926 Thrombin signalling through proteinase activated receptors (PARs) 8 LFUL005446-PA;LFUL003526-PA;LFUL012255-PA;LFUL000640-PA;LFUL000620-PA;LFUL014137-PA;LFUL017104-PA;LFUL003893-PA KEGG: 00480+4.3.2.7 Glutathione metabolism 3 LFUL011898-PA;LFUL012272-PA;LFUL011897-PA KEGG: 04150+2.7.11.24 mTOR signaling pathway 3 LFUL014137-PA;LFUL014138-PA;LFUL004667-PA Reactome: R-HSA-202040 G-protein activation 6 LFUL012255-PA;LFUL000620-PA;LFUL000640-PA;LFUL000404-PA;LFUL003893-PA;LFUL017104-PA Reactome: R-HSA-2129379 Molecules associated with elastic fibres 5 LFUL008110-PA;LFUL008111-PA;LFUL011271-PA;LFUL003428-PA;LFUL004227-PA KEGG: 00620+4.4.1.5 Pyruvate metabolism 1 LFUL015126-PA KEGG: 00260+5.4.2.11 Glycine, serine and threonine metabolism 1 LFUL008386-PA Reactome: R-HSA-111448 Activation of NOXA and translocation to mitochondria 1 LFUL000101-PA MetaCyc: PWY-6972 Oleandomycin activation/inactivation 1 LFUL019455-PA KEGG: 00760+2.7.1.23 Nicotinate and nicotinamide metabolism 2 LFUL009108-PA;LFUL005193-PA Reactome: R-HSA-111458 Formation of apoptosome 6 LFUL018372-PA;LFUL004784-PA;LFUL016074-PA;LFUL001636-PA;LFUL002198-PA;LFUL007046-PA Reactome: R-HSA-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex 4 LFUL012191-PA;LFUL013894-PA;LFUL013893-PA;LFUL015328-PA Reactome: R-HSA-5610780 Degradation of GLI1 by the proteasome 42 LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL003914-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL005128-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL007901-PA;LFUL015255-PA;LFUL017243-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL005608-PA;LFUL014805-PA;LFUL015886-PA;LFUL001632-PA;LFUL001413-PA;LFUL008156-PA;LFUL013520-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL009758-PA;LFUL004900-PA;LFUL017218-PA;LFUL017219-PA;LFUL015402-PA;LFUL011816-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA KEGG: 00565+3.1.3.4 Ether lipid metabolism 3 LFUL011019-PA;LFUL005920-PA;LFUL011020-PA Reactome: R-HSA-113501 Inhibition of replication initiation of damaged DNA by RB1/E2F1 5 LFUL007804-PA;LFUL002178-PA;LFUL001174-PA;LFUL000101-PA;LFUL009032-PA Reactome: R-HSA-444257 RSK activation 2 LFUL014137-PA;LFUL000924-PA KEGG: 00790+2.8.1.12 Folate biosynthesis 1 LFUL003909-PA Reactome: R-HSA-1489509 DAG and IP3 signaling 3 LFUL018399-PA;LFUL009249-PA;LFUL009246-PA KEGG: 00051+5.4.2.8 Fructose and mannose metabolism 1 LFUL000192-PA Reactome: R-HSA-1614635 Sulfur amino acid metabolism 2 LFUL002123-PA;LFUL002702-PA KEGG: 00512+2.4.1.122 Mucin type O-glycan biosynthesis 3 LFUL018255-PA;LFUL019109-PA;LFUL004586-PA Reactome: R-HSA-8875360 InlB-mediated entry of Listeria monocytogenes into host cell 3 LFUL013808-PA;LFUL004537-PA;LFUL005095-PA KEGG: 00062+4.2.1.17+1.1.1.211 Fatty acid elongation 1 LFUL017943-PA Reactome: R-HSA-5689901 Metalloprotease DUBs 8 LFUL011470-PA;LFUL001928-PA;LFUL013202-PA;LFUL004282-PA;LFUL013266-PA;LFUL004537-PA;LFUL001667-PA;LFUL001929-PA Reactome: R-HSA-1482839 Acyl chain remodelling of PE 13 LFUL002457-PA;LFUL013309-PA;LFUL008296-PA;LFUL008301-PA;LFUL008302-PA;LFUL012016-PA;LFUL011621-PA;LFUL004585-PA;LFUL008298-PA;LFUL013308-PA;LFUL008299-PA;LFUL016881-PA;LFUL013311-PA MetaCyc: PWY-4702 Phytate degradation I 1 LFUL003784-PA Reactome: R-HSA-390650 Histamine receptors 1 LFUL011364-PA Reactome: R-HSA-9636383 Prevention of phagosomal-lysosomal fusion 3 LFUL013321-PA;LFUL013808-PA;LFUL004537-PA Reactome: R-HSA-8866423 VLDL assembly 10 LFUL018059-PA;LFUL000686-PA;LFUL013537-PA;LFUL005945-PA;LFUL009525-PA;LFUL018058-PA;LFUL012561-PA;LFUL019397-PA;LFUL013535-PA;LFUL018063-PA KEGG: 00051+2.7.1.105+3.1.3.46 Fructose and mannose metabolism 2 LFUL005759-PA;LFUL010045-PA Reactome: R-HSA-2142691 Synthesis of Leukotrienes (LT) and Eoxins (EX) 3 LFUL000104-PA;LFUL000874-PA;LFUL000084-PA Reactome: R-HSA-8849175 Threonine catabolism 2 LFUL014152-PA;LFUL014729-PA Reactome: R-HSA-167158 Formation of the HIV-1 Early Elongation Complex 29 LFUL000564-PA;LFUL010467-PA;LFUL010456-PA;LFUL003393-PA;LFUL008550-PA;LFUL008827-PA;LFUL013636-PA;LFUL006932-PA;LFUL010468-PA;LFUL016326-PA;LFUL001373-PA;LFUL007672-PA;LFUL003284-PA;LFUL010620-PA;LFUL018856-PA;LFUL013037-PA;LFUL015513-PA;LFUL008825-PA;LFUL010364-PA;LFUL014212-PA;LFUL000565-PA;LFUL014608-PA;LFUL006416-PA;LFUL003397-PA;LFUL003797-PA;LFUL004554-PA;LFUL016324-PA;LFUL006931-PA;LFUL000398-PA KEGG: 00730+2.7.6.2 Thiamine metabolism 1 LFUL006365-PA Reactome: R-HSA-211897 Cytochrome P450 - arranged by substrate type 1 LFUL002651-PA KEGG: 00770+2.7.1.24 Pantothenate and CoA biosynthesis 2 LFUL013489-PA;LFUL001707-PA KEGG: 00071+1.14.14.1 Fatty acid degradation 2 LFUL007894-PA;LFUL019543-PA KEGG: 00330+2.6.1.13 Arginine and proline metabolism 1 LFUL014392-PA KEGG: 00650+4.1.3.4 Butanoate metabolism 1 LFUL018576-PA Reactome: R-HSA-5693579 Homologous DNA Pairing and Strand Exchange 20 LFUL001598-PA;LFUL007836-PA;LFUL006936-PA;LFUL001126-PA;LFUL007979-PA;LFUL007096-PA;LFUL002671-PA;LFUL003121-PA;LFUL003753-PA;LFUL007471-PA;LFUL004270-PA;LFUL004632-PA;LFUL011482-PA;LFUL014004-PA;LFUL010680-PA;LFUL014965-PA;LFUL004631-PA;LFUL008071-PA;LFUL005650-PA;LFUL007832-PA MetaCyc: PWY-6700 Queuosine biosynthesis I (de novo) 2 LFUL003796-PA;LFUL001075-PA MetaCyc: PWY-7821 Tunicamycin biosynthesis 4 LFUL011207-PA;LFUL000002-PA;LFUL014206-PA;LFUL011206-PA Reactome: R-HSA-8951936 RUNX3 regulates p14-ARF 4 LFUL009516-PA;LFUL009514-PA;LFUL009515-PA;LFUL009513-PA MetaCyc: PWY-4841 UDP-alpha-D-glucuronate biosynthesis (from myo-inositol) 1 LFUL005679-PA Reactome: R-HSA-3065676 SUMO is conjugated to E1 (UBA2:SAE1) 1 LFUL009574-PA MetaCyc: PWY-7766 Heme b biosynthesis IV (Gram-positive bacteria) 1 LFUL000195-PA Reactome: R-HSA-1912399 Pre-NOTCH Processing in the Endoplasmic Reticulum 3 LFUL006223-PA;LFUL018752-PA;LFUL000252-PA Reactome: R-HSA-5635838 Activation of SMO 7 LFUL005058-PA;LFUL003136-PA;LFUL005059-PA;LFUL003137-PA;LFUL000313-PA;LFUL017925-PA;LFUL016392-PA Reactome: R-HSA-168638 NOD1/2 Signaling Pathway 6 LFUL004537-PA;LFUL004784-PA;LFUL018125-PA;LFUL010280-PA;LFUL005189-PA;LFUL018127-PA MetaCyc: PWY-7141 (3S)-linalool biosynthesis 2 LFUL004955-PA;LFUL011744-PA Reactome: R-HSA-9010553 Regulation of expression of SLITs and ROBOs 132 LFUL009774-PA;LFUL009487-PA;LFUL014785-PA;LFUL017218-PA;LFUL015591-PA;LFUL005171-PA;LFUL004900-PA;LFUL012852-PA;LFUL012372-PA;LFUL016069-PA;LFUL010331-PA;LFUL013520-PA;LFUL004420-PA;LFUL004636-PA;LFUL001176-PA;LFUL006788-PA;LFUL004637-PA;LFUL006902-PA;LFUL004418-PA;LFUL000664-PA;LFUL014935-PA;LFUL003261-PA;LFUL002673-PA;LFUL015255-PA;LFUL007901-PA;LFUL019500-PA;LFUL009485-PA;LFUL003221-PA;LFUL006688-PA;LFUL015825-PA;LFUL016822-PA;LFUL000695-PA;LFUL001717-PA;LFUL019638-PA;LFUL017436-PA;LFUL013851-PA;LFUL003914-PA;LFUL005935-PA;LFUL013277-PA;LFUL016786-PA;LFUL011817-PA;LFUL010441-PA;LFUL011816-PA;LFUL009758-PA;LFUL011123-PA;LFUL001183-PA;LFUL014304-PA;LFUL001413-PA;LFUL018435-PA;LFUL015696-PA;LFUL008669-PA;LFUL010862-PA;LFUL004914-PA;LFUL005594-PA;LFUL017243-PA;LFUL005657-PA;LFUL013396-PA;LFUL007583-PA;LFUL019054-PA;LFUL011278-PA;LFUL014893-PA;LFUL002208-PA;LFUL017656-PA;LFUL001681-PA;LFUL009759-PA;LFUL018953-PA;LFUL018532-PA;LFUL008016-PA;LFUL016060-PA;LFUL018996-PA;LFUL015402-PA;LFUL010275-PA;LFUL010697-PA;LFUL016059-PA;LFUL018065-PA;LFUL015920-PA;LFUL002950-PA;LFUL001632-PA;LFUL008330-PA;LFUL004915-PA;LFUL011563-PA;LFUL002212-PA;LFUL003567-PA;LFUL011000-PA;LFUL010852-PA;LFUL004537-PA;LFUL001329-PA;LFUL000565-PA;LFUL006255-PA;LFUL018450-PA;LFUL001669-PA;LFUL017408-PA;LFUL004885-PA;LFUL000050-PA;LFUL006784-PA;LFUL018531-PA;LFUL014225-PA;LFUL018534-PA;LFUL007684-PA;LFUL003913-PA;LFUL006093-PA;LFUL017219-PA;LFUL002249-PA;LFUL014007-PA;LFUL019701-PA;LFUL006675-PA;LFUL010327-PA;LFUL017608-PA;LFUL008661-PA;LFUL002925-PA;LFUL018772-PA;LFUL014805-PA;LFUL004596-PA;LFUL007452-PA;LFUL017447-PA;LFUL000564-PA;LFUL005608-PA;LFUL009630-PA;LFUL016970-PA;LFUL007358-PA;LFUL017793-PA;LFUL012702-PA;LFUL001667-PA;LFUL002148-PA;LFUL005128-PA;LFUL019578-PA;LFUL001102-PA;LFUL004974-PA;LFUL006720-PA;LFUL013254-PA;LFUL012271-PA;LFUL003947-PA Reactome: R-HSA-9609736 Assembly and cell surface presentation of NMDA receptors 19 LFUL012256-PA;LFUL013560-PA;LFUL010848-PA;LFUL014799-PA;LFUL004646-PA;LFUL010682-PA;LFUL013557-PA;LFUL010847-PA;LFUL002885-PA;LFUL014795-PA;LFUL014800-PA;LFUL013561-PA;LFUL003377-PA;LFUL014801-PA;LFUL010020-PA;LFUL018841-PA;LFUL013555-PA;LFUL010681-PA;LFUL014793-PA KEGG: 00670+4.3.1.4+2.1.2.5 One carbon pool by folate 1 LFUL005329-PA KEGG: 00230+4.1.1.21 Purine metabolism 1 LFUL017018-PA Reactome: R-HSA-425393 Transport of inorganic cations/anions and amino acids/oligopeptides 1 LFUL000432-PA Reactome: R-HSA-5576893 Phase 2 - plateau phase 8 LFUL006730-PA;LFUL014649-PA;LFUL014650-PA;LFUL011579-PA;LFUL015922-PA;LFUL011901-PA;LFUL013366-PA;LFUL011903-PA Reactome: R-HSA-1855183 Synthesis of IP2, IP, and Ins in the cytosol 8 LFUL003784-PA;LFUL008204-PA;LFUL012052-PA;LFUL005679-PA;LFUL014193-PA;LFUL009747-PA;LFUL012051-PA;LFUL008439-PA MetaCyc: PWY-7800 Ac/N-end rule pathway 3 LFUL006276-PA;LFUL000406-PA;LFUL008335-PA KEGG: 00010+4.1.2.13 Glycolysis / Gluconeogenesis 1 LFUL011512-PA KEGG: 00620+3.6.1.7 Pyruvate metabolism 1 LFUL009013-PA Reactome: R-HSA-68827 CDT1 association with the CDC6:ORC:origin complex 47 LFUL001413-PA;LFUL001632-PA;LFUL001183-PA;LFUL010331-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL013520-PA;LFUL005608-PA;LFUL014805-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL015871-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL004900-PA;LFUL012083-PA;LFUL009758-PA;LFUL015402-PA;LFUL014586-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL014903-PA;LFUL012409-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL005128-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL003914-PA;LFUL003567-PA;LFUL012084-PA;LFUL016970-PA;LFUL000664-PA;LFUL002734-PA;LFUL017243-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL005657-PA;LFUL015255-PA Reactome: R-HSA-6796648 TP53 Regulates Transcription of DNA Repair Genes 43 LFUL002536-PA;LFUL011503-PA;LFUL008343-PA;LFUL001373-PA;LFUL010468-PA;LFUL003393-PA;LFUL008827-PA;LFUL013636-PA;LFUL000900-PA;LFUL016324-PA;LFUL008342-PA;LFUL011501-PA;LFUL016724-PA;LFUL004061-PA;LFUL003397-PA;LFUL001092-PA;LFUL010620-PA;LFUL018856-PA;LFUL015513-PA;LFUL008825-PA;LFUL001415-PA;LFUL006936-PA;LFUL016326-PA;LFUL014905-PA;LFUL006932-PA;LFUL011502-PA;LFUL008550-PA;LFUL004885-PA;LFUL010467-PA;LFUL012191-PA;LFUL010456-PA;LFUL000398-PA;LFUL006931-PA;LFUL002212-PA;LFUL004554-PA;LFUL006416-PA;LFUL014608-PA;LFUL003797-PA;LFUL013037-PA;LFUL003284-PA;LFUL007672-PA;LFUL014212-PA;LFUL010364-PA Reactome: R-HSA-418592 ADP signalling through P2Y purinoceptor 1 5 LFUL012255-PA;LFUL000620-PA;LFUL003893-PA;LFUL017104-PA;LFUL000640-PA Reactome: R-HSA-349425 Autodegradation of the E3 ubiquitin ligase COP1 42 LFUL003567-PA;LFUL016970-PA;LFUL000664-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL007901-PA;LFUL001667-PA;LFUL013396-PA;LFUL005657-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL006936-PA;LFUL005128-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL003914-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL001413-PA;LFUL001632-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL014403-PA;LFUL005608-PA;LFUL014805-PA KEGG: 04926+2.7.11.1 Relaxin signaling pathway 50 LFUL018447-PA;LFUL002766-PA;LFUL000251-PA;LFUL018448-PA;LFUL016885-PA;LFUL001476-PA;LFUL000247-PA;LFUL013749-PA;LFUL004673-PA;LFUL006034-PA;LFUL008438-PA;LFUL000550-PA;LFUL010552-PA;LFUL004423-PA;LFUL010551-PA;LFUL013361-PA;LFUL016077-PA;LFUL012699-PA;LFUL000058-PA;LFUL017285-PA;LFUL000059-PA;LFUL009466-PA;LFUL001475-PA;LFUL004296-PA;LFUL016685-PA;LFUL000924-PA;LFUL006336-PA;LFUL015097-PA;LFUL000250-PA;LFUL006176-PA;LFUL001467-PA;LFUL003791-PA;LFUL015598-PA;LFUL000248-PA;LFUL019451-PA;LFUL003065-PA;LFUL015336-PA;LFUL010118-PA;LFUL001132-PA;LFUL015132-PA;LFUL012191-PA;LFUL014180-PA;LFUL008160-PA;LFUL014459-PA;LFUL006936-PA;LFUL000249-PA;LFUL005999-PA;LFUL014316-PA;LFUL003125-PA;LFUL000595-PA Reactome: R-HSA-159227 Transport of the SLBP independent Mature mRNA 24 LFUL002666-PA;LFUL000564-PA;LFUL005156-PA;LFUL015687-PA;LFUL006282-PA;LFUL018131-PA;LFUL009840-PA;LFUL013801-PA;LFUL010864-PA;LFUL000581-PA;LFUL005157-PA;LFUL000200-PA;LFUL006358-PA;LFUL011549-PA;LFUL005565-PA;LFUL016880-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL000565-PA;LFUL002533-PA;LFUL008059-PA;LFUL016186-PA Reactome: R-HSA-2979096 NOTCH2 Activation and Transmission of Signal to the Nucleus 11 LFUL000672-PA;LFUL000121-PA;LFUL008785-PA;LFUL004537-PA;LFUL003906-PA;LFUL009679-PA;LFUL019751-PA;LFUL005973-PA;LFUL000671-PA;LFUL004221-PA;LFUL018390-PA KEGG: 00230+2.4.2.7 Purine metabolism 1 LFUL004695-PA Reactome: R-HSA-4341670 Defective NEU1 causes sialidosis 1 LFUL010970-PA Reactome: R-HSA-8866427 VLDLR internalisation and degradation 4 LFUL011104-PA;LFUL007853-PA;LFUL007491-PA;LFUL000575-PA MetaCyc: PWY-7111 Pyruvate fermentation to isobutanol (engineered) 1 LFUL019679-PA Reactome: R-HSA-71336 Pentose phosphate pathway 8 LFUL014002-PA;LFUL012465-PA;LFUL013845-PA;LFUL006583-PA;LFUL012294-PA;LFUL009918-PA;LFUL002759-PA;LFUL005639-PA KEGG: 00130+1.17.4.4 Ubiquinone and other terpenoid-quinone biosynthesis 1 LFUL001171-PA KEGG: 00760+3.1.3.5 Nicotinate and nicotinamide metabolism 2 LFUL011206-PA;LFUL011207-PA KEGG: 00270+2.1.1.37 Cysteine and methionine metabolism 4 LFUL019841-PA;LFUL013804-PA;LFUL003902-PA;LFUL019792-PA Reactome: R-HSA-211733 Regulation of activated PAK-2p34 by proteasome mediated degradation 40 LFUL005608-PA;LFUL014805-PA;LFUL001632-PA;LFUL001413-PA;LFUL013520-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL018065-PA;LFUL017608-PA;LFUL009758-PA;LFUL004900-PA;LFUL017218-PA;LFUL017219-PA;LFUL015402-PA;LFUL011816-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL003914-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL005128-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL007901-PA;LFUL015255-PA;LFUL017243-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA Reactome: R-HSA-167242 Abortive elongation of HIV-1 transcript in the absence of Tat 20 LFUL006931-PA;LFUL000398-PA;LFUL016324-PA;LFUL014608-PA;LFUL003397-PA;LFUL003797-PA;LFUL007672-PA;LFUL003284-PA;LFUL010620-PA;LFUL018856-PA;LFUL013037-PA;LFUL008825-PA;LFUL010364-PA;LFUL000565-PA;LFUL016326-PA;LFUL001373-PA;LFUL006932-PA;LFUL008550-PA;LFUL008827-PA;LFUL000564-PA KEGG: 00340+2.1.1.22 Histidine metabolism 1 LFUL010993-PA MetaCyc: PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I 3 LFUL013571-PA;LFUL013568-PA;LFUL017016-PA Reactome: R-HSA-174084 Autodegradation of Cdh1 by Cdh1:APC/C 50 LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL009758-PA;LFUL004900-PA;LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL001632-PA;LFUL002279-PA;LFUL011826-PA;LFUL001413-PA;LFUL013520-PA;LFUL004085-PA;LFUL011827-PA;LFUL010327-PA;LFUL018065-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL000448-PA;LFUL013953-PA;LFUL005608-PA;LFUL014805-PA;LFUL011394-PA;LFUL006691-PA;LFUL016970-PA;LFUL000664-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL017243-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL005128-PA;LFUL008983-PA;LFUL001285-PA;LFUL013254-PA;LFUL006784-PA;LFUL006381-PA;LFUL009759-PA;LFUL003914-PA KEGG: 00230+6.3.4.13 Purine metabolism 1 LFUL013571-PA MetaCyc: PWY-7820 Teichuronic acid biosynthesis (B. subtilis 168) 1 LFUL010590-PA Reactome: R-HSA-425381 Bicarbonate transporters 4 LFUL019618-PA;LFUL000333-PA;LFUL000332-PA;LFUL014177-PA Reactome: R-HSA-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 18 LFUL000920-PA;LFUL004185-PA;LFUL008021-PA;LFUL000404-PA;LFUL005926-PA;LFUL007016-PA;LFUL017104-PA;LFUL003893-PA;LFUL009144-PA;LFUL000640-PA;LFUL010663-PA;LFUL007162-PA;LFUL001282-PA;LFUL000620-PA;LFUL001283-PA;LFUL017103-PA;LFUL012255-PA;LFUL019738-PA KEGG: 00240+2.4.2.10 Pyrimidine metabolism 1 LFUL006717-PA Reactome: R-HSA-9630222 Defective NTHL1 substrate binding 1 LFUL014324-PA KEGG: 00230+6.3.4.4 Purine metabolism 3 LFUL017382-PA;LFUL017381-PA;LFUL019525-PA KEGG: 00010+1.1.1.27 Glycolysis / Gluconeogenesis 1 LFUL015394-PA KEGG: 00195+7.1.2.2 Photosynthesis 5 LFUL016356-PA;LFUL014557-PA;LFUL014559-PA;LFUL006212-PA;LFUL003394-PA Reactome: R-HSA-167162 RNA Polymerase II HIV Promoter Escape 35 LFUL017944-PA;LFUL004554-PA;LFUL006931-PA;LFUL014212-PA;LFUL015240-PA;LFUL010364-PA;LFUL013037-PA;LFUL004050-PA;LFUL003284-PA;LFUL016337-PA;LFUL004052-PA;LFUL006416-PA;LFUL006932-PA;LFUL014887-PA;LFUL010456-PA;LFUL014888-PA;LFUL010467-PA;LFUL000689-PA;LFUL008550-PA;LFUL004051-PA;LFUL016703-PA;LFUL013957-PA;LFUL008825-PA;LFUL015513-PA;LFUL010620-PA;LFUL018856-PA;LFUL019760-PA;LFUL018855-PA;LFUL010468-PA;LFUL001373-PA;LFUL005318-PA;LFUL016338-PA;LFUL008827-PA;LFUL013636-PA;LFUL003393-PA MetaCyc: PWY-7384 Anaerobic energy metabolism (invertebrates, mitochondrial) 7 LFUL017635-PA;LFUL017636-PA;LFUL006146-PA;LFUL016366-PA;LFUL004029-PA;LFUL005914-PA;LFUL006472-PA Reactome: R-HSA-6806664 Metabolism of vitamin K 2 LFUL001171-PA;LFUL008229-PA Reactome: R-HSA-381753 Olfactory Signaling Pathway 2 LFUL013841-PA;LFUL000235-PA MetaCyc: PWY-6958 Icosapentaenoate biosynthesis I (lower eukaryotes) 2 LFUL010698-PA;LFUL001272-PA Reactome: R-HSA-9620244 Long-term potentiation 4 LFUL018841-PA;LFUL002885-PA;LFUL010847-PA;LFUL010848-PA Reactome: R-HSA-2559585 Oncogene Induced Senescence 8 LFUL014137-PA;LFUL015531-PA;LFUL015532-PA;LFUL000101-PA;LFUL004232-PA;LFUL004537-PA;LFUL005454-PA;LFUL006745-PA MetaCyc: PWY-5738 GDP-6-deoxy-D-talose biosynthesis 1 LFUL002512-PA KEGG: 00521+3.1.3.25 Streptomycin biosynthesis 1 LFUL003784-PA KEGG: 00970+6.1.1.14 Aminoacyl-tRNA biosynthesis 1 LFUL011768-PA Reactome: R-HSA-1483166 Synthesis of PA 21 LFUL000334-PA;LFUL013311-PA;LFUL012016-PA;LFUL017312-PA;LFUL013308-PA;LFUL004585-PA;LFUL016131-PA;LFUL002099-PA;LFUL010965-PA;LFUL013309-PA;LFUL013338-PA;LFUL016881-PA;LFUL009878-PA;LFUL011621-PA;LFUL008878-PA;LFUL016130-PA;LFUL014100-PA;LFUL017634-PA;LFUL016045-PA;LFUL009158-PA;LFUL016603-PA Reactome: R-HSA-4615885 SUMOylation of DNA replication proteins 26 LFUL009840-PA;LFUL018131-PA;LFUL013801-PA;LFUL005156-PA;LFUL006282-PA;LFUL015687-PA;LFUL002666-PA;LFUL019068-PA;LFUL006665-PA;LFUL016186-PA;LFUL008059-PA;LFUL002533-PA;LFUL009303-PA;LFUL013881-PA;LFUL002532-PA;LFUL009305-PA;LFUL011549-PA;LFUL006358-PA;LFUL000200-PA;LFUL005157-PA;LFUL007608-PA;LFUL005565-PA;LFUL016880-PA;LFUL010864-PA;LFUL000581-PA;LFUL007607-PA Reactome: R-HSA-5625970 RHO GTPases activate KTN1 2 LFUL001638-PA;LFUL005324-PA KEGG: 00513+2.4.1.131 Various types of N-glycan biosynthesis 1 LFUL011924-PA MetaCyc: PWY-6932 Selenate reduction 1 LFUL019316-PA MetaCyc: PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) 3 LFUL014713-PA;LFUL007957-PA;LFUL019642-PA Reactome: R-HSA-3785653 Myoclonic epilepsy of Lafora 1 LFUL004537-PA Reactome: R-HSA-5625900 RHO GTPases activate CIT 2 LFUL016885-PA;LFUL013236-PA MetaCyc: PWY-6642 (R)-cysteate degradation 2 LFUL003406-PA;LFUL011379-PA KEGG: 00400+1.14.16.1 Phenylalanine, tyrosine and tryptophan biosynthesis 1 LFUL004045-PA KEGG: 00230+4.6.1.2 Purine metabolism 7 LFUL016952-PA;LFUL003347-PA;LFUL015110-PA;LFUL012580-PA;LFUL015111-PA;LFUL004870-PA;LFUL003623-PA KEGG: 00720+4.2.1.17 Carbon fixation pathways in prokaryotes 1 LFUL017943-PA KEGG: 00030+5.3.1.9 Pentose phosphate pathway 1 LFUL001099-PA MetaCyc: PWY-2942 L-lysine biosynthesis III 1 LFUL009128-PA Reactome: R-HSA-70688 Proline catabolism 4 LFUL014994-PA;LFUL011522-PA;LFUL012268-PA;LFUL014993-PA Reactome: R-HSA-947581 Molybdenum cofactor biosynthesis 8 LFUL008950-PA;LFUL003909-PA;LFUL004970-PA;LFUL008951-PA;LFUL009927-PA;LFUL004972-PA;LFUL009929-PA;LFUL007012-PA KEGG: 00970+6.1.1.21 Aminoacyl-tRNA biosynthesis 1 LFUL009161-PA Reactome: R-HSA-432142 Platelet sensitization by LDL 7 LFUL009310-PA;LFUL018058-PA;LFUL005945-PA;LFUL018059-PA;LFUL015628-PA;LFUL013535-PA;LFUL019397-PA MetaCyc: PWY-6598 Sciadonate biosynthesis 18 LFUL006533-PA;LFUL012361-PA;LFUL002423-PA;LFUL013814-PA;LFUL010698-PA;LFUL012359-PA;LFUL015420-PA;LFUL013815-PA;LFUL001272-PA;LFUL017948-PA;LFUL001095-PA;LFUL013817-PA;LFUL013816-PA;LFUL007078-PA;LFUL004766-PA;LFUL015422-PA;LFUL013818-PA;LFUL012360-PA MetaCyc: PWY-5497 Purine nucleobases degradation II (anaerobic) 7 LFUL001565-PA;LFUL011735-PA;LFUL005329-PA;LFUL003915-PA;LFUL004544-PA;LFUL014192-PA;LFUL009609-PA Reactome: R-HSA-4608870 Asymmetric localization of PCP proteins 42 LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL005666-PA;LFUL003914-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL005128-PA;LFUL017243-PA;LFUL015255-PA;LFUL001667-PA;LFUL004537-PA;LFUL007901-PA;LFUL013396-PA;LFUL005657-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL005608-PA;LFUL014805-PA;LFUL001413-PA;LFUL001632-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL010331-PA;LFUL001183-PA;LFUL013520-PA;LFUL005667-PA;LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA MetaCyc: PWY-5857 Ubiquinol-10 biosynthesis (prokaryotic) 4 LFUL017908-PA;LFUL000814-PA;LFUL017907-PA;LFUL002067-PA MetaCyc: PWY-7831 ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide 4 LFUL015209-PA;LFUL014202-PA;LFUL008153-PA;LFUL004664-PA Reactome: R-HSA-8876725 Protein methylation 8 LFUL007466-PA;LFUL018858-PA;LFUL003931-PA;LFUL015533-PA;LFUL015591-PA;LFUL011674-PA;LFUL005006-PA;LFUL000797-PA Reactome: R-HSA-380259 Loss of Nlp from mitotic centrosomes 17 LFUL003889-PA;LFUL009096-PA;LFUL018303-PA;LFUL010041-PA;LFUL004460-PA;LFUL014621-PA;LFUL009757-PA;LFUL010789-PA;LFUL009638-PA;LFUL011516-PA;LFUL001762-PA;LFUL015517-PA;LFUL004301-PA;LFUL007649-PA;LFUL015311-PA;LFUL017541-PA;LFUL002675-PA Reactome: R-HSA-8951911 RUNX3 regulates RUNX1-mediated transcription 4 LFUL009516-PA;LFUL009514-PA;LFUL009515-PA;LFUL009513-PA Reactome: R-HSA-139915 Activation of PUMA and translocation to mitochondria 2 LFUL000101-PA;LFUL008605-PA KEGG: 00254+6.4.1.2 Aflatoxin biosynthesis 1 LFUL005606-PA KEGG: 00250+2.6.1.1 Alanine, aspartate and glutamate metabolism 2 LFUL003406-PA;LFUL011379-PA Reactome: R-HSA-8939902 Regulation of RUNX2 expression and activity 47 LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL009515-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL011816-PA;LFUL009514-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA;LFUL015886-PA;LFUL009516-PA;LFUL014805-PA;LFUL005608-PA;LFUL010552-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL005657-PA;LFUL009513-PA;LFUL005128-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL005953-PA;LFUL003914-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA Reactome: R-HSA-1296061 HCN channels 1 LFUL000206-PA KEGG: 00550+2.7.8.13 Peptidoglycan biosynthesis 1 LFUL006200-PA Reactome: R-HSA-5578775 Ion homeostasis 14 LFUL009247-PA;LFUL006995-PA;LFUL006994-PA;LFUL009246-PA;LFUL009412-PA;LFUL013584-PA;LFUL013581-PA;LFUL009789-PA;LFUL002885-PA;LFUL006996-PA;LFUL004627-PA;LFUL009411-PA;LFUL009249-PA;LFUL003076-PA Reactome: R-HSA-168138 Toll Like Receptor 9 (TLR9) Cascade 1 LFUL004611-PA KEGG: 00010+1.2.1.12 Glycolysis / Gluconeogenesis 1 LFUL015710-PA Reactome: R-HSA-196299 Beta-catenin phosphorylation cascade 5 LFUL007844-PA;LFUL015628-PA;LFUL005304-PA;LFUL009310-PA;LFUL010552-PA Reactome: R-HSA-8849932 Synaptic adhesion-like molecules 7 LFUL018841-PA;LFUL010847-PA;LFUL017918-PA;LFUL002596-PA;LFUL002597-PA;LFUL010848-PA;LFUL017919-PA Reactome: R-HSA-9617828 FOXO-mediated transcription of cell cycle genes 1 LFUL010367-PA KEGG: 00480+6.3.2.2 Glutathione metabolism 2 LFUL008713-PA;LFUL019657-PA MetaCyc: PWY-6963 Ammonia assimilation cycle I 1 LFUL012349-PA Reactome: R-HSA-2206291 MPS IIIC - Sanfilippo syndrome C 1 LFUL003653-PA MetaCyc: PWY-7807 Glyphosate degradation III 4 LFUL004386-PA;LFUL004778-PA;LFUL004695-PA;LFUL007408-PA Reactome: R-HSA-1368108 BMAL1:CLOCK,NPAS2 activates circadian gene expression 2 LFUL015835-PA;LFUL018367-PA Reactome: R-HSA-176187 Activation of ATR in response to replication stress 26 LFUL014494-PA;LFUL002760-PA;LFUL006063-PA;LFUL012130-PA;LFUL012191-PA;LFUL008688-PA;LFUL013345-PA;LFUL007704-PA;LFUL009340-PA;LFUL017714-PA;LFUL012409-PA;LFUL014903-PA;LFUL004598-PA;LFUL017711-PA;LFUL002563-PA;LFUL012083-PA;LFUL004865-PA;LFUL012084-PA;LFUL015871-PA;LFUL007817-PA;LFUL002734-PA;LFUL005736-PA;LFUL001437-PA;LFUL019733-PA;LFUL012288-PA;LFUL018628-PA Reactome: R-HSA-5467348 Truncations of AMER1 destabilize the destruction complex 4 LFUL007844-PA;LFUL015628-PA;LFUL010552-PA;LFUL009310-PA MetaCyc: PWY-6545 Pyrimidine deoxyribonucleotides de novo biosynthesis III 30 LFUL014941-PA;LFUL019252-PA;LFUL014206-PA;LFUL014063-PA;LFUL005983-PA;LFUL019261-PA;LFUL017852-PA;LFUL017739-PA;LFUL006960-PA;LFUL003861-PA;LFUL015842-PA;LFUL005848-PA;LFUL011295-PA;LFUL008033-PA;LFUL005981-PA;LFUL013859-PA;LFUL003582-PA;LFUL004087-PA;LFUL019301-PA;LFUL008100-PA;LFUL001680-PA;LFUL013124-PA;LFUL017179-PA;LFUL016612-PA;LFUL005425-PA;LFUL004400-PA;LFUL018976-PA;LFUL013982-PA;LFUL000002-PA;LFUL008636-PA MetaCyc: PWY-8053 Anandamide biosynthesis II 30 LFUL013310-PA;LFUL009878-PA;LFUL008878-PA;LFUL011621-PA;LFUL002722-PA;LFUL002721-PA;LFUL016881-PA;LFUL016032-PA;LFUL012592-PA;LFUL016031-PA;LFUL016035-PA;LFUL016034-PA;LFUL016045-PA;LFUL016603-PA;LFUL002720-PA;LFUL014100-PA;LFUL017634-PA;LFUL012016-PA;LFUL013308-PA;LFUL004585-PA;LFUL011019-PA;LFUL016033-PA;LFUL010843-PA;LFUL013307-PA;LFUL013311-PA;LFUL019491-PA;LFUL011020-PA;LFUL013309-PA;LFUL002099-PA;LFUL005920-PA KEGG: 00020+1.2.4.2 Citrate cycle (TCA cycle) 5 LFUL003936-PA;LFUL006666-PA;LFUL003935-PA;LFUL006667-PA;LFUL003940-PA Reactome: R-HSA-8983711 OAS antiviral response 1 LFUL010863-PA KEGG: 00520+3.5.99.6 Amino sugar and nucleotide sugar metabolism 2 LFUL009918-PA;LFUL005858-PA Reactome: R-HSA-390648 Muscarinic acetylcholine receptors 1 LFUL015037-PA Reactome: R-HSA-5619039 Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN) 1 LFUL012406-PA MetaCyc: PWY-7177 UTP and CTP dephosphorylation II 2 LFUL003025-PA;LFUL003026-PA Reactome: R-HSA-4420097 VEGFA-VEGFR2 Pathway 13 LFUL001108-PA;LFUL007866-PA;LFUL000248-PA;LFUL007647-PA;LFUL007646-PA;LFUL005324-PA;LFUL001602-PA;LFUL018066-PA;LFUL000512-PA;LFUL017955-PA;LFUL018067-PA;LFUL006764-PA;LFUL009466-PA Reactome: R-HSA-9608287 Defective MUTYH substrate binding 1 LFUL014324-PA KEGG: 00603+3.2.1.52 Glycosphingolipid biosynthesis - globo and isoglobo series 11 LFUL003459-PA;LFUL010431-PA;LFUL001685-PA;LFUL003458-PA;LFUL006590-PA;LFUL007928-PA;LFUL003457-PA;LFUL003417-PA;LFUL006704-PA;LFUL003460-PA;LFUL015340-PA KEGG: 00280+1.2.1.27 Valine, leucine and isoleucine degradation 1 LFUL014148-PA KEGG: 00770+6.3.2.5 Pantothenate and CoA biosynthesis 1 LFUL006727-PA Reactome: R-HSA-983168 Antigen processing: Ubiquitination & Proteasome degradation 150 LFUL002212-PA;LFUL011297-PA;LFUL006691-PA;LFUL014721-PA;LFUL013275-PA;LFUL003567-PA;LFUL011298-PA;LFUL004537-PA;LFUL011530-PA;LFUL018149-PA;LFUL006820-PA;LFUL001254-PA;LFUL006508-PA;LFUL017408-PA;LFUL017892-PA;LFUL009236-PA;LFUL004885-PA;LFUL007983-PA;LFUL005953-PA;LFUL006784-PA;LFUL014936-PA;LFUL006381-PA;LFUL011407-PA;LFUL005464-PA;LFUL015406-PA;LFUL009702-PA;LFUL015402-PA;LFUL002710-PA;LFUL008199-PA;LFUL004085-PA;LFUL006914-PA;LFUL018148-PA;LFUL018065-PA;LFUL001867-PA;LFUL001632-PA;LFUL002279-PA;LFUL011826-PA;LFUL000319-PA;LFUL016970-PA;LFUL008316-PA;LFUL001667-PA;LFUL008483-PA;LFUL005465-PA;LFUL002045-PA;LFUL009423-PA;LFUL005128-PA;LFUL006278-PA;LFUL001285-PA;LFUL013254-PA;LFUL001406-PA;LFUL008981-PA;LFUL007684-PA;LFUL018299-PA;LFUL017651-PA;LFUL009894-PA;LFUL003913-PA;LFUL017219-PA;LFUL009576-PA;LFUL004212-PA;LFUL002195-PA;LFUL010327-PA;LFUL002708-PA;LFUL017608-PA;LFUL005810-PA;LFUL011529-PA;LFUL002709-PA;LFUL001997-PA;LFUL014805-PA;LFUL001480-PA;LFUL012646-PA;LFUL005608-PA;LFUL014711-PA;LFUL015428-PA;LFUL000664-PA;LFUL011394-PA;LFUL007901-PA;LFUL015255-PA;LFUL015405-PA;LFUL002919-PA;LFUL015191-PA;LFUL000944-PA;LFUL019638-PA;LFUL015825-PA;LFUL009675-PA;LFUL016875-PA;LFUL003914-PA;LFUL016470-PA;LFUL004595-PA;LFUL001478-PA;LFUL015189-PA;LFUL009774-PA;LFUL009424-PA;LFUL005954-PA;LFUL009122-PA;LFUL000079-PA;LFUL003505-PA;LFUL017218-PA;LFUL000078-PA;LFUL015987-PA;LFUL004900-PA;LFUL013331-PA;LFUL013520-PA;LFUL010331-PA;LFUL011827-PA;LFUL015886-PA;LFUL015407-PA;LFUL014156-PA;LFUL013953-PA;LFUL004210-PA;LFUL002044-PA;LFUL010036-PA;LFUL018300-PA;LFUL010585-PA;LFUL000615-PA;LFUL005657-PA;LFUL013396-PA;LFUL001205-PA;LFUL017243-PA;LFUL010453-PA;LFUL002382-PA;LFUL008983-PA;LFUL000596-PA;LFUL005598-PA;LFUL011122-PA;LFUL006397-PA;LFUL009759-PA;LFUL008484-PA;LFUL010426-PA;LFUL013277-PA;LFUL003941-PA;LFUL016951-PA;LFUL003841-PA;LFUL002973-PA;LFUL011817-PA;LFUL010441-PA;LFUL011816-PA;LFUL007969-PA;LFUL009758-PA;LFUL001361-PA;LFUL002975-PA;LFUL010014-PA;LFUL018621-PA;LFUL001183-PA;LFUL008718-PA;LFUL004005-PA;LFUL001413-PA;LFUL013244-PA;LFUL010229-PA;LFUL014990-PA;LFUL001360-PA Reactome: R-HSA-8957275 Post-translational protein phosphorylation 14 LFUL014908-PA;LFUL016095-PA;LFUL014909-PA;LFUL018059-PA;LFUL005945-PA;LFUL013535-PA;LFUL019397-PA;LFUL002086-PA;LFUL017984-PA;LFUL001330-PA;LFUL001624-PA;LFUL010285-PA;LFUL002553-PA;LFUL018058-PA Reactome: R-HSA-447038 NrCAM interactions 1 LFUL018841-PA KEGG: 00052+3.2.1.23 Galactose metabolism 6 LFUL012024-PA;LFUL012258-PA;LFUL006883-PA;LFUL010554-PA;LFUL010553-PA;LFUL010555-PA MetaCyc: PWY-6859 All-trans-farnesol biosynthesis 3 LFUL008593-PA;LFUL011744-PA;LFUL004955-PA Reactome: R-HSA-186763 Downstream signal transduction 2 LFUL002707-PA;LFUL001806-PA Reactome: R-HSA-975144 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation 4 LFUL004537-PA;LFUL014254-PA;LFUL010280-PA;LFUL014255-PA Reactome: R-HSA-380994 ATF4 activates genes in response to endoplasmic reticulum stress 16 LFUL018238-PA;LFUL011544-PA;LFUL005206-PA;LFUL000163-PA;LFUL015691-PA;LFUL010888-PA;LFUL015271-PA;LFUL015112-PA;LFUL001175-PA;LFUL008294-PA;LFUL008668-PA;LFUL003227-PA;LFUL013449-PA;LFUL003231-PA;LFUL000541-PA;LFUL006413-PA Reactome: R-HSA-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest 3 LFUL000101-PA;LFUL013765-PA;LFUL006665-PA Reactome: R-HSA-351202 Metabolism of polyamines 3 LFUL011332-PA;LFUL016360-PA;LFUL005994-PA Reactome: R-HSA-170822 Regulation of Glucokinase by Glucokinase Regulatory Protein 22 LFUL016186-PA;LFUL008059-PA;LFUL002533-PA;LFUL009303-PA;LFUL002532-PA;LFUL013881-PA;LFUL009305-PA;LFUL011549-PA;LFUL000200-PA;LFUL006358-PA;LFUL005157-PA;LFUL005565-PA;LFUL016880-PA;LFUL010864-PA;LFUL000581-PA;LFUL009840-PA;LFUL018131-PA;LFUL013801-PA;LFUL005156-PA;LFUL015687-PA;LFUL006282-PA;LFUL002666-PA MetaCyc: PWY-6724 Starch degradation II 1 LFUL003990-PA Reactome: R-HSA-5693607 Processing of DNA double-strand break ends 31 LFUL012602-PA;LFUL008071-PA;LFUL010359-PA;LFUL005650-PA;LFUL013266-PA;LFUL004537-PA;LFUL007832-PA;LFUL015191-PA;LFUL014004-PA;LFUL010680-PA;LFUL005736-PA;LFUL014965-PA;LFUL004631-PA;LFUL001437-PA;LFUL018628-PA;LFUL013202-PA;LFUL014494-PA;LFUL017172-PA;LFUL002760-PA;LFUL004632-PA;LFUL007228-PA;LFUL014198-PA;LFUL012191-PA;LFUL008688-PA;LFUL011470-PA;LFUL007836-PA;LFUL006936-PA;LFUL001126-PA;LFUL013345-PA;LFUL007096-PA;LFUL002671-PA KEGG: 04070+2.7.1.159 Phosphatidylinositol signaling system 1 LFUL007957-PA Reactome: R-HSA-8931987 RUNX1 regulates estrogen receptor mediated transcription 4 LFUL009515-PA;LFUL009513-PA;LFUL009516-PA;LFUL009514-PA KEGG: 00550+2.4.1.227 Peptidoglycan biosynthesis 1 LFUL009636-PA KEGG: 00564+2.7.1.32+2.7.1.82 Glycerophospholipid metabolism 1 LFUL001619-PA KEGG: 00520+3.2.1.52 Amino sugar and nucleotide sugar metabolism 11 LFUL006704-PA;LFUL003417-PA;LFUL007928-PA;LFUL003457-PA;LFUL015340-PA;LFUL003460-PA;LFUL003458-PA;LFUL001685-PA;LFUL003459-PA;LFUL010431-PA;LFUL006590-PA KEGG: 05165+2.7.11.1 Human papillomavirus infection 50 LFUL002766-PA;LFUL018447-PA;LFUL018448-PA;LFUL016885-PA;LFUL001476-PA;LFUL000251-PA;LFUL000550-PA;LFUL010552-PA;LFUL004423-PA;LFUL000247-PA;LFUL013749-PA;LFUL004673-PA;LFUL006034-PA;LFUL008438-PA;LFUL016077-PA;LFUL012699-PA;LFUL017285-PA;LFUL000058-PA;LFUL000059-PA;LFUL009466-PA;LFUL001475-PA;LFUL004296-PA;LFUL010551-PA;LFUL013361-PA;LFUL000250-PA;LFUL006176-PA;LFUL000924-PA;LFUL016685-PA;LFUL006336-PA;LFUL015097-PA;LFUL003791-PA;LFUL015598-PA;LFUL001467-PA;LFUL010118-PA;LFUL001132-PA;LFUL015132-PA;LFUL008160-PA;LFUL014180-PA;LFUL012191-PA;LFUL000248-PA;LFUL019451-PA;LFUL003065-PA;LFUL015336-PA;LFUL005999-PA;LFUL014316-PA;LFUL003125-PA;LFUL000595-PA;LFUL014459-PA;LFUL006936-PA;LFUL000249-PA MetaCyc: PWY-6619 Adenine and adenosine salvage VI 1 LFUL017738-PA KEGG: 00970+6.1.1.18 Aminoacyl-tRNA biosynthesis 1 LFUL003447-PA Reactome: R-HSA-9033807 ABO blood group biosynthesis 4 LFUL008153-PA;LFUL004664-PA;LFUL015209-PA;LFUL014202-PA KEGG: 00564+3.1.1.4 Glycerophospholipid metabolism 9 LFUL013309-PA;LFUL012016-PA;LFUL013310-PA;LFUL011621-PA;LFUL013308-PA;LFUL004585-PA;LFUL016881-PA;LFUL013311-PA;LFUL013307-PA MetaCyc: PWY-6679 Jadomycin biosynthesis 1 LFUL005606-PA Reactome: R-HSA-391160 Signal regulatory protein family interactions 2 LFUL013097-PA;LFUL001108-PA Reactome: R-HSA-1660661 Sphingolipid de novo biosynthesis 9 LFUL007538-PA;LFUL002773-PA;LFUL014880-PA;LFUL010227-PA;LFUL012011-PA;LFUL002774-PA;LFUL005823-PA;LFUL002776-PA;LFUL016336-PA Reactome: R-HSA-389357 CD28 dependent PI3K/Akt signaling 10 LFUL005288-PA;LFUL006140-PA;LFUL000924-PA;LFUL010339-PA;LFUL007170-PA;LFUL019533-PA;LFUL001475-PA;LFUL001476-PA;LFUL014130-PA;LFUL006181-PA KEGG: 00592+1.3.3.6 alpha-Linolenic acid metabolism 2 LFUL001448-PA;LFUL001447-PA KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14 Fatty acid biosynthesis 1 LFUL006083-PA MetaCyc: PWY-5989 Stearate biosynthesis II (bacteria and plants) 1 LFUL006083-PA Reactome: R-HSA-8866654 E3 ubiquitin ligases ubiquitinate target proteins 22 LFUL017996-PA;LFUL017998-PA;LFUL005006-PA;LFUL018619-PA;LFUL002527-PA;LFUL018001-PA;LFUL011128-PA;LFUL011326-PA;LFUL006665-PA;LFUL010318-PA;LFUL010850-PA;LFUL004531-PA;LFUL004537-PA;LFUL012096-PA;LFUL007352-PA;LFUL002209-PA;LFUL007854-PA;LFUL019616-PA;LFUL018072-PA;LFUL002435-PA;LFUL011127-PA;LFUL016449-PA Reactome: R-HSA-72203 Processing of Capped Intron-Containing Pre-mRNA 14 LFUL017940-PA;LFUL006932-PA;LFUL001373-PA;LFUL006931-PA;LFUL000565-PA;LFUL010364-PA;LFUL008825-PA;LFUL003284-PA;LFUL010620-PA;LFUL013037-PA;LFUL018856-PA;LFUL000564-PA;LFUL008827-PA;LFUL008550-PA Reactome: R-HSA-400042 Adrenaline,noradrenaline inhibits insulin secretion 5 LFUL017104-PA;LFUL003893-PA;LFUL000640-PA;LFUL000620-PA;LFUL012255-PA Reactome: R-HSA-167290 Pausing and recovery of HIV elongation 24 LFUL003797-PA;LFUL003397-PA;LFUL014608-PA;LFUL008825-PA;LFUL010364-PA;LFUL003284-PA;LFUL010620-PA;LFUL013037-PA;LFUL018856-PA;LFUL007672-PA;LFUL000398-PA;LFUL006931-PA;LFUL002212-PA;LFUL016324-PA;LFUL008342-PA;LFUL008827-PA;LFUL004885-PA;LFUL008550-PA;LFUL001373-PA;LFUL008343-PA;LFUL016326-PA;LFUL001415-PA;LFUL002536-PA;LFUL006932-PA KEGG: 00720+1.5.1.5+3.5.4.9 Carbon fixation pathways in prokaryotes 2 LFUL003915-PA;LFUL014192-PA Reactome: R-HSA-5654706 FRS-mediated FGFR3 signaling 1 LFUL006796-PA KEGG: 00330+1.2.1.88 Arginine and proline metabolism 1 LFUL012268-PA MetaCyc: PWY-7269 NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast) 2 LFUL005193-PA;LFUL009108-PA MetaCyc: PWY-5466 Matairesinol biosynthesis 7 LFUL010194-PA;LFUL010193-PA;LFUL006897-PA;LFUL006904-PA;LFUL010195-PA;LFUL004976-PA;LFUL019366-PA KEGG: 00270+6.3.2.2 Cysteine and methionine metabolism 2 LFUL008713-PA;LFUL019657-PA Reactome: R-HSA-382556 ABC-family proteins mediated transport 50 LFUL001157-PA;LFUL017243-PA;LFUL004537-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL015255-PA;LFUL016970-PA;LFUL000664-PA;LFUL002211-PA;LFUL003567-PA;LFUL013516-PA;LFUL003914-PA;LFUL016539-PA;LFUL005006-PA;LFUL009759-PA;LFUL003449-PA;LFUL006784-PA;LFUL013254-PA;LFUL007460-PA;LFUL005128-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL009774-PA;LFUL019455-PA;LFUL004108-PA;LFUL007684-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL014805-PA;LFUL005608-PA;LFUL001421-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA KEGG: 00531+3.2.1.52 Glycosaminoglycan degradation 11 LFUL003459-PA;LFUL010431-PA;LFUL001685-PA;LFUL003458-PA;LFUL006590-PA;LFUL003417-PA;LFUL006704-PA;LFUL007928-PA;LFUL003457-PA;LFUL015340-PA;LFUL003460-PA Reactome: R-HSA-5662702 Melanin biosynthesis 9 LFUL018537-PA;LFUL018618-PA;LFUL002224-PA;LFUL019370-PA;LFUL010170-PA;LFUL018535-PA;LFUL005805-PA;LFUL018539-PA;LFUL018540-PA MetaCyc: PWY-6317 D-galactose degradation I (Leloir pathway) 6 LFUL006901-PA;LFUL002992-PA;LFUL004776-PA;LFUL010337-PA;LFUL015403-PA;LFUL010336-PA Reactome: R-HSA-174417 Telomere C-strand (Lagging Strand) Synthesis 3 LFUL006665-PA;LFUL005720-PA;LFUL007960-PA Reactome: R-HSA-72706 GTP hydrolysis and joining of the 60S ribosomal subunit 92 LFUL015591-PA;LFUL010275-PA;LFUL005171-PA;LFUL010697-PA;LFUL012852-PA;LFUL012372-PA;LFUL016059-PA;LFUL016060-PA;LFUL009487-PA;LFUL006873-PA;LFUL018996-PA;LFUL001962-PA;LFUL006788-PA;LFUL004637-PA;LFUL008330-PA;LFUL011563-PA;LFUL006902-PA;LFUL016069-PA;LFUL016269-PA;LFUL015920-PA;LFUL002950-PA;LFUL004420-PA;LFUL004636-PA;LFUL015341-PA;LFUL001176-PA;LFUL003261-PA;LFUL002673-PA;LFUL006445-PA;LFUL001640-PA;LFUL004537-PA;LFUL001329-PA;LFUL004418-PA;LFUL011000-PA;LFUL010852-PA;LFUL017436-PA;LFUL013851-PA;LFUL005935-PA;LFUL000050-PA;LFUL019500-PA;LFUL009485-PA;LFUL006255-PA;LFUL003221-PA;LFUL018450-PA;LFUL006688-PA;LFUL000695-PA;LFUL001717-PA;LFUL002249-PA;LFUL014007-PA;LFUL006675-PA;LFUL019701-PA;LFUL011123-PA;LFUL004229-PA;LFUL014225-PA;LFUL001463-PA;LFUL006093-PA;LFUL007452-PA;LFUL004596-PA;LFUL017447-PA;LFUL008669-PA;LFUL010862-PA;LFUL008661-PA;LFUL018435-PA;LFUL014304-PA;LFUL000390-PA;LFUL002925-PA;LFUL015696-PA;LFUL018772-PA;LFUL012702-PA;LFUL009762-PA;LFUL007583-PA;LFUL017288-PA;LFUL009630-PA;LFUL002324-PA;LFUL007358-PA;LFUL002211-PA;LFUL017793-PA;LFUL010424-PA;LFUL014893-PA;LFUL011278-PA;LFUL005636-PA;LFUL002208-PA;LFUL017656-PA;LFUL001681-PA;LFUL001102-PA;LFUL018953-PA;LFUL012271-PA;LFUL004974-PA;LFUL006720-PA;LFUL008016-PA;LFUL003947-PA;LFUL001937-PA;LFUL019054-PA MetaCyc: PWY-5994 Palmitate biosynthesis (animals and fungi, cytoplasm) 1 LFUL006083-PA MetaCyc: PWY-1042 Glycolysis IV (plant cytosol) 8 LFUL011512-PA;LFUL011354-PA;LFUL001192-PA;LFUL005591-PA;LFUL008549-PA;LFUL015710-PA;LFUL011112-PA;LFUL011355-PA Reactome: R-HSA-196783 Coenzyme A biosynthesis 4 LFUL010292-PA;LFUL016820-PA;LFUL012867-PA;LFUL006727-PA Reactome: R-HSA-212300 PRC2 methylates histones and DNA 7 LFUL004849-PA;LFUL019841-PA;LFUL019792-PA;LFUL007465-PA;LFUL007754-PA;LFUL003902-PA;LFUL016716-PA Reactome: R-HSA-2029482 Regulation of actin dynamics for phagocytic cup formation 21 LFUL005324-PA;LFUL001602-PA;LFUL007319-PA;LFUL018066-PA;LFUL007647-PA;LFUL007646-PA;LFUL007345-PA;LFUL009182-PA;LFUL002340-PA;LFUL007866-PA;LFUL006764-PA;LFUL010301-PA;LFUL018067-PA;LFUL005511-PA;LFUL000512-PA;LFUL005434-PA;LFUL013420-PA;LFUL006478-PA;LFUL015508-PA;LFUL017955-PA;LFUL014137-PA MetaCyc: PWY-6123 Inosine-5'-phosphate biosynthesis I 4 LFUL001229-PA;LFUL017018-PA;LFUL015685-PA;LFUL015684-PA KEGG: 00240+3.5.4.5 Pyrimidine metabolism 1 LFUL011652-PA Reactome: R-HSA-1482922 Acyl chain remodelling of PI 13 LFUL016881-PA;LFUL013311-PA;LFUL012016-PA;LFUL011621-PA;LFUL013308-PA;LFUL004585-PA;LFUL008299-PA;LFUL008298-PA;LFUL013309-PA;LFUL002457-PA;LFUL008296-PA;LFUL008301-PA;LFUL008302-PA Reactome: R-HSA-5358747 S33 mutants of beta-catenin aren't phosphorylated 4 LFUL009310-PA;LFUL010552-PA;LFUL007844-PA;LFUL015628-PA KEGG: 00982+1.14.14.1 Drug metabolism - cytochrome P450 2 LFUL019543-PA;LFUL007894-PA Reactome: R-HSA-3656253 Defective EXT1 causes exostoses 1, TRPS2 and CHDS 7 LFUL009642-PA;LFUL005814-PA;LFUL003069-PA;LFUL002623-PA;LFUL003070-PA;LFUL002624-PA;LFUL003068-PA Reactome: R-HSA-420029 Tight junction interactions 2 LFUL001096-PA;LFUL008468-PA KEGG: 00230+3.6.1.15 Purine metabolism 1 LFUL005425-PA Reactome: R-HSA-426048 Arachidonate production from DAG 2 LFUL011925-PA;LFUL011856-PA KEGG: 00908+2.5.1.75 Zeatin biosynthesis 2 LFUL011679-PA;LFUL011678-PA KEGG: 00010+3.1.3.11 Glycolysis / Gluconeogenesis 2 LFUL000567-PA;LFUL000566-PA Reactome: R-HSA-5682910 LGI-ADAM interactions 2 LFUL012020-PA;LFUL012021-PA Reactome: R-HSA-5602498 MyD88 deficiency (TLR2/4) 1 LFUL018800-PA KEGG: 00510+2.4.1.260 N-Glycan biosynthesis 1 LFUL013830-PA KEGG: 00564+4.1.1.65 Glycerophospholipid metabolism 1 LFUL011031-PA Reactome: R-HSA-156711 Polo-like kinase mediated events 2 LFUL014149-PA;LFUL014016-PA KEGG: 00640+1.1.1.27 Propanoate metabolism 1 LFUL015394-PA Reactome: R-HSA-6803204 TP53 Regulates Transcription of Genes Involved in Cytochrome C Release 3 LFUL010236-PA;LFUL008605-PA;LFUL006936-PA Reactome: R-HSA-5467333 APC truncation mutants are not K63 polyubiquitinated 1 LFUL007844-PA Reactome: R-HSA-5578749 Transcriptional regulation by small RNAs 31 LFUL018131-PA;LFUL008550-PA;LFUL009840-PA;LFUL013801-PA;LFUL005156-PA;LFUL015687-PA;LFUL006282-PA;LFUL002666-PA;LFUL001373-PA;LFUL006932-PA;LFUL008059-PA;LFUL002533-PA;LFUL016186-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL013037-PA;LFUL003284-PA;LFUL010620-PA;LFUL010364-PA;LFUL006358-PA;LFUL012019-PA;LFUL000200-PA;LFUL005157-PA;LFUL011549-PA;LFUL006931-PA;LFUL005565-PA;LFUL016880-PA;LFUL010864-PA;LFUL000581-PA Reactome: R-HSA-2151209 Activation of PPARGC1A (PGC-1alpha) by phosphorylation 2 LFUL005590-PA;LFUL001585-PA KEGG: 00330+2.6.1.1 Arginine and proline metabolism 2 LFUL003406-PA;LFUL011379-PA Reactome: R-HSA-5685938 HDR through Single Strand Annealing (SSA) 22 LFUL001126-PA;LFUL013345-PA;LFUL008688-PA;LFUL007836-PA;LFUL006936-PA;LFUL002671-PA;LFUL007096-PA;LFUL002760-PA;LFUL014494-PA;LFUL004632-PA;LFUL006135-PA;LFUL005736-PA;LFUL010680-PA;LFUL014004-PA;LFUL018628-PA;LFUL014965-PA;LFUL004631-PA;LFUL001437-PA;LFUL008071-PA;LFUL002340-PA;LFUL005650-PA;LFUL007832-PA Reactome: R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) 14 LFUL004537-PA;LFUL006381-PA;LFUL000448-PA;LFUL013953-PA;LFUL006691-PA;LFUL001285-PA;LFUL011827-PA;LFUL004085-PA;LFUL014137-PA;LFUL008983-PA;LFUL014905-PA;LFUL002279-PA;LFUL011826-PA;LFUL011394-PA Reactome: R-HSA-9014325 TICAM1,TRAF6-dependent induction of TAK1 complex 4 LFUL018127-PA;LFUL005189-PA;LFUL004537-PA;LFUL018125-PA Reactome: R-HSA-73614 Pyrimidine salvage 7 LFUL006725-PA;LFUL015755-PA;LFUL015135-PA;LFUL018006-PA;LFUL005855-PA;LFUL011652-PA;LFUL017794-PA Reactome: R-HSA-3065678 SUMO is transferred from E1 to E2 (UBE2I, UBC9) 1 LFUL009574-PA Reactome: R-HSA-1482788 Acyl chain remodelling of PC 24 LFUL008302-PA;LFUL008301-PA;LFUL008296-PA;LFUL019491-PA;LFUL013309-PA;LFUL002457-PA;LFUL004585-PA;LFUL008298-PA;LFUL013308-PA;LFUL012016-PA;LFUL016033-PA;LFUL010843-PA;LFUL013311-PA;LFUL016035-PA;LFUL016034-PA;LFUL002720-PA;LFUL008299-PA;LFUL002722-PA;LFUL011621-PA;LFUL012592-PA;LFUL016031-PA;LFUL016881-PA;LFUL002721-PA;LFUL016032-PA MetaCyc: PWY-6898 Thiamine salvage III 1 LFUL006365-PA Reactome: R-HSA-201688 WNT mediated activation of DVL 2 LFUL007162-PA;LFUL016359-PA Reactome: R-HSA-159231 Transport of Mature mRNA Derived from an Intronless Transcript 31 LFUL017090-PA;LFUL016186-PA;LFUL017089-PA;LFUL002533-PA;LFUL008059-PA;LFUL000565-PA;LFUL009303-PA;LFUL002532-PA;LFUL004759-PA;LFUL013881-PA;LFUL009305-PA;LFUL005565-PA;LFUL016880-PA;LFUL011549-PA;LFUL005157-PA;LFUL000200-PA;LFUL006358-PA;LFUL000581-PA;LFUL010864-PA;LFUL013801-PA;LFUL009840-PA;LFUL018131-PA;LFUL017088-PA;LFUL006282-PA;LFUL015687-PA;LFUL017085-PA;LFUL000564-PA;LFUL005156-PA;LFUL002666-PA;LFUL015919-PA;LFUL004758-PA KEGG: 00240+2.7.4.6 Pyrimidine metabolism 7 LFUL008636-PA;LFUL011295-PA;LFUL005981-PA;LFUL013982-PA;LFUL017739-PA;LFUL005983-PA;LFUL017852-PA Reactome: R-HSA-446203 Asparagine N-linked glycosylation 4 LFUL008532-PA;LFUL002678-PA;LFUL008997-PA;LFUL017220-PA Reactome: R-HSA-8951430 RUNX3 regulates WNT signaling 2 LFUL008435-PA;LFUL005993-PA Reactome: R-HSA-193648 NRAGE signals death through JNK 16 LFUL013611-PA;LFUL001301-PA;LFUL003790-PA;LFUL015382-PA;LFUL001155-PA;LFUL019649-PA;LFUL018037-PA;LFUL014579-PA;LFUL014180-PA;LFUL019644-PA;LFUL003791-PA;LFUL001303-PA;LFUL013612-PA;LFUL001466-PA;LFUL004990-PA;LFUL008198-PA MetaCyc: PWY-6863 Pyruvate fermentation to hexanol (engineered) 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA MetaCyc: PWY-801 Homocysteine and cysteine interconversion 2 LFUL013723-PA;LFUL013724-PA Reactome: R-HSA-936440 Negative regulators of DDX58/IFIH1 signaling 6 LFUL018695-PA;LFUL015758-PA;LFUL004537-PA;LFUL001182-PA;LFUL009193-PA;LFUL017649-PA KEGG: 00130+1.14.99.60 Ubiquinone and other terpenoid-quinone biosynthesis 1 LFUL000814-PA MetaCyc: PWY-7601 Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes) 18 LFUL001272-PA;LFUL017948-PA;LFUL001095-PA;LFUL013817-PA;LFUL007078-PA;LFUL013816-PA;LFUL013818-PA;LFUL015422-PA;LFUL004766-PA;LFUL012360-PA;LFUL006533-PA;LFUL012361-PA;LFUL002423-PA;LFUL013814-PA;LFUL010698-PA;LFUL012359-PA;LFUL015420-PA;LFUL013815-PA MetaCyc: PWY-5083 NAD/NADH phosphorylation and dephosphorylation 2 LFUL005193-PA;LFUL009108-PA MetaCyc: PWY-7036 Very long chain fatty acid biosynthesis II 18 LFUL001272-PA;LFUL001095-PA;LFUL017948-PA;LFUL007078-PA;LFUL013816-PA;LFUL013817-PA;LFUL012360-PA;LFUL004766-PA;LFUL015422-PA;LFUL013818-PA;LFUL006533-PA;LFUL002423-PA;LFUL012361-PA;LFUL012359-PA;LFUL010698-PA;LFUL013814-PA;LFUL013815-PA;LFUL015420-PA Reactome: R-HSA-8964046 VLDL clearance 6 LFUL019397-PA;LFUL013535-PA;LFUL018059-PA;LFUL005945-PA;LFUL018058-PA;LFUL011104-PA Reactome: R-HSA-110362 POLB-Dependent Long Patch Base Excision Repair 5 LFUL017395-PA;LFUL003658-PA;LFUL009126-PA;LFUL008002-PA;LFUL017393-PA MetaCyc: PWY-7410 Ipsdienol biosynthesis 2 LFUL004955-PA;LFUL011744-PA Reactome: R-HSA-164939 Nef mediated downregulation of CD28 cell surface expression 1 LFUL007853-PA KEGG: 00515+2.4.1.109 Mannose type O-glycan biosynthesis 7 LFUL003439-PA;LFUL003052-PA;LFUL003866-PA;LFUL003867-PA;LFUL009334-PA;LFUL007240-PA;LFUL002764-PA KEGG: 00030+2.7.6.1 Pentose phosphate pathway 3 LFUL006507-PA;LFUL006506-PA;LFUL002929-PA MetaCyc: PWY-7193 Pyrimidine ribonucleosides salvage I 3 LFUL017794-PA;LFUL011652-PA;LFUL018006-PA Reactome: R-HSA-2122948 Activated NOTCH1 Transmits Signal to the Nucleus 13 LFUL009679-PA;LFUL009003-PA;LFUL019751-PA;LFUL005973-PA;LFUL000671-PA;LFUL015476-PA;LFUL004221-PA;LFUL018390-PA;LFUL000672-PA;LFUL000121-PA;LFUL008785-PA;LFUL004537-PA;LFUL003906-PA Reactome: R-HSA-68952 DNA replication initiation 7 LFUL002178-PA;LFUL007277-PA;LFUL009325-PA;LFUL009032-PA;LFUL001174-PA;LFUL007804-PA;LFUL007279-PA Reactome: R-HSA-110320 Translesion Synthesis by POLH 20 LFUL008688-PA;LFUL013345-PA;LFUL006914-PA;LFUL011669-PA;LFUL012033-PA;LFUL012029-PA;LFUL006665-PA;LFUL012031-PA;LFUL014494-PA;LFUL016875-PA;LFUL002760-PA;LFUL005006-PA;LFUL014502-PA;LFUL011668-PA;LFUL005736-PA;LFUL001437-PA;LFUL004537-PA;LFUL003903-PA;LFUL011672-PA;LFUL012030-PA Reactome: R-HSA-975155 MyD88 dependent cascade initiated on endosome 1 LFUL018800-PA KEGG: 00500+2.4.1.18 Starch and sucrose metabolism 3 LFUL014478-PA;LFUL007973-PA;LFUL014477-PA KEGG: 00970+6.1.1.15 Aminoacyl-tRNA biosynthesis 3 LFUL013267-PA;LFUL015627-PA;LFUL015626-PA Reactome: R-HSA-9616222 Transcriptional regulation of granulopoiesis 6 LFUL009516-PA;LFUL006695-PA;LFUL009514-PA;LFUL009515-PA;LFUL000101-PA;LFUL009513-PA Reactome: R-HSA-69166 Removal of the Flap Intermediate 11 LFUL009126-PA;LFUL005736-PA;LFUL007804-PA;LFUL002178-PA;LFUL006665-PA;LFUL001437-PA;LFUL001174-PA;LFUL005650-PA;LFUL007960-PA;LFUL005720-PA;LFUL009032-PA Reactome: R-HSA-912631 Regulation of signaling by CBL 3 LFUL004537-PA;LFUL014130-PA;LFUL002707-PA Reactome: R-HSA-429947 Deadenylation of mRNA 18 LFUL016269-PA;LFUL007365-PA;LFUL014931-PA;LFUL006098-PA;LFUL018435-PA;LFUL008408-PA;LFUL000511-PA;LFUL001139-PA;LFUL014924-PA;LFUL011911-PA;LFUL000163-PA;LFUL002731-PA;LFUL014926-PA;LFUL002732-PA;LFUL014923-PA;LFUL001140-PA;LFUL006347-PA;LFUL014929-PA KEGG: 00360+2.6.1.1 Phenylalanine metabolism 2 LFUL011379-PA;LFUL003406-PA MetaCyc: PWY-7778 2-methylpropene degradation 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA Reactome: R-HSA-5357905 Regulation of TNFR1 signaling 7 LFUL013163-PA;LFUL010280-PA;LFUL015733-PA;LFUL012768-PA;LFUL012769-PA;LFUL015734-PA;LFUL004537-PA Reactome: R-HSA-2730905 Role of LAT2/NTAL/LAB on calcium mobilization 1 LFUL000924-PA Reactome: R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures 6 LFUL009021-PA;LFUL000176-PA;LFUL013341-PA;LFUL007858-PA;LFUL019569-PA;LFUL008274-PA Reactome: R-HSA-3000171 Non-integrin membrane-ECM interactions 10 LFUL019569-PA;LFUL005332-PA;LFUL004915-PA;LFUL009021-PA;LFUL002807-PA;LFUL013341-PA;LFUL004914-PA;LFUL010340-PA;LFUL002806-PA;LFUL000176-PA KEGG: 00720+1.1.1.42 Carbon fixation pathways in prokaryotes 2 LFUL012684-PA;LFUL006558-PA Reactome: R-HSA-9634635 Estrogen-stimulated signaling through PRKCZ 1 LFUL000924-PA Reactome: R-HSA-159740 Gamma-carboxylation of protein precursors 1 LFUL006033-PA KEGG: 00380+4.2.1.17 Tryptophan metabolism 1 LFUL017943-PA Reactome: R-HSA-6782315 tRNA modification in the nucleus and cytosol 29 LFUL015627-PA;LFUL003488-PA;LFUL009836-PA;LFUL006072-PA;LFUL002189-PA;LFUL014407-PA;LFUL006754-PA;LFUL017092-PA;LFUL015272-PA;LFUL011678-PA;LFUL008958-PA;LFUL009835-PA;LFUL016637-PA;LFUL004569-PA;LFUL011663-PA;LFUL011125-PA;LFUL011055-PA;LFUL005873-PA;LFUL003143-PA;LFUL001075-PA;LFUL003353-PA;LFUL009539-PA;LFUL014459-PA;LFUL007916-PA;LFUL003796-PA;LFUL017053-PA;LFUL011662-PA;LFUL011679-PA;LFUL013267-PA MetaCyc: PWY-7204 Pyridoxal 5'-phosphate salvage II (plants) 4 LFUL009425-PA;LFUL012528-PA;LFUL013559-PA;LFUL006014-PA MetaCyc: PWY-2781 Cis-zeatin biosynthesis 2 LFUL011679-PA;LFUL011678-PA Reactome: R-HSA-189451 Heme biosynthesis 11 LFUL007802-PA;LFUL001554-PA;LFUL017816-PA;LFUL005083-PA;LFUL003153-PA;LFUL000195-PA;LFUL011673-PA;LFUL007835-PA;LFUL015294-PA;LFUL011432-PA;LFUL001555-PA Reactome: R-HSA-4551295 Defective ALG11 causes ALG11-CDG (CDG-1p) 1 LFUL011924-PA KEGG: 00670+6.3.4.3 One carbon pool by folate 1 LFUL003915-PA Reactome: R-HSA-390522 Striated Muscle Contraction 9 LFUL019784-PB;LFUL019784-PD;LFUL019784-PA;LFUL019784-PC;LFUL019787-PA;LFUL004588-PA;LFUL019787-PB;LFUL004592-PA;LFUL004589-PA MetaCyc: PWY-7803 Trna splicing II 2 LFUL016205-PA;LFUL008437-PA Reactome: R-HSA-937039 IRAK1 recruits IKK complex 4 LFUL014255-PA;LFUL010280-PA;LFUL014254-PA;LFUL004537-PA KEGG: 00460+3.5.1.1 Cyanoamino acid metabolism 1 LFUL004768-PA Reactome: R-HSA-72702 Ribosomal scanning and start codon recognition 51 LFUL015920-PA;LFUL016269-PA;LFUL018772-PA;LFUL001176-PA;LFUL018435-PA;LFUL004420-PA;LFUL000390-PA;LFUL002925-PA;LFUL004636-PA;LFUL015341-PA;LFUL004637-PA;LFUL001962-PA;LFUL006788-PA;LFUL011563-PA;LFUL004229-PA;LFUL018996-PA;LFUL001463-PA;LFUL006873-PA;LFUL015591-PA;LFUL012852-PA;LFUL006675-PA;LFUL019701-PA;LFUL016059-PA;LFUL005171-PA;LFUL014007-PA;LFUL001937-PA;LFUL001717-PA;LFUL006688-PA;LFUL002208-PA;LFUL001681-PA;LFUL014893-PA;LFUL005636-PA;LFUL013851-PA;LFUL012271-PA;LFUL006720-PA;LFUL003947-PA;LFUL005935-PA;LFUL001102-PA;LFUL002211-PA;LFUL004418-PA;LFUL009630-PA;LFUL002324-PA;LFUL010852-PA;LFUL017793-PA;LFUL010424-PA;LFUL011000-PA;LFUL012702-PA;LFUL001640-PA;LFUL009762-PA;LFUL006445-PA;LFUL017288-PA Reactome: R-HSA-3304356 SMAD2/3 Phosphorylation Motif Mutants in Cancer 1 LFUL011859-PA MetaCyc: PWY-7184 Pyrimidine deoxyribonucleotides de novo biosynthesis I 32 LFUL008100-PA;LFUL013124-PA;LFUL017179-PA;LFUL003582-PA;LFUL013859-PA;LFUL000002-PA;LFUL019252-PA;LFUL014206-PA;LFUL015842-PA;LFUL005848-PA;LFUL011295-PA;LFUL008033-PA;LFUL017852-PA;LFUL017739-PA;LFUL019301-PA;LFUL001680-PA;LFUL005981-PA;LFUL004087-PA;LFUL002258-PA;LFUL008636-PA;LFUL016612-PA;LFUL005425-PA;LFUL018976-PA;LFUL004400-PA;LFUL013982-PA;LFUL002259-PA;LFUL014063-PA;LFUL014941-PA;LFUL005983-PA;LFUL019261-PA;LFUL006960-PA;LFUL003861-PA KEGG: 00260+2.1.2.10 Glycine, serine and threonine metabolism 4 LFUL000003-PA;LFUL017290-PA;LFUL012257-PA;LFUL004012-PA KEGG: 00640+6.2.1.5 Propanoate metabolism 4 LFUL016366-PA;LFUL004029-PA;LFUL005914-PA;LFUL006472-PA KEGG: 00710+1.2.1.12 Carbon fixation in photosynthetic organisms 1 LFUL015710-PA MetaCyc: PWY-6952 Glycerophosphodiester degradation 1 LFUL000334-PA KEGG: 00970+6.1.1.6 Aminoacyl-tRNA biosynthesis 1 LFUL014891-PA Reactome: R-HSA-70221 Glycogen breakdown (glycogenolysis) 8 LFUL017806-PA;LFUL012958-PA;LFUL017805-PA;LFUL017799-PA;LFUL003990-PA;LFUL010675-PA;LFUL017804-PA;LFUL017801-PA Reactome: R-HSA-264876 Insulin processing 11 LFUL004647-PA;LFUL004648-PA;LFUL006790-PA;LFUL012655-PA;LFUL014118-PA;LFUL014617-PA;LFUL013117-PA;LFUL003097-PA;LFUL007698-PA;LFUL007699-PA;LFUL013119-PA Reactome: R-HSA-174154 APC/C:Cdc20 mediated degradation of Securin 51 LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL005128-PA;LFUL008983-PA;LFUL001285-PA;LFUL013254-PA;LFUL006784-PA;LFUL006381-PA;LFUL009759-PA;LFUL003914-PA;LFUL011394-PA;LFUL003567-PA;LFUL000664-PA;LFUL006691-PA;LFUL016970-PA;LFUL015255-PA;LFUL007901-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL017243-PA;LFUL001632-PA;LFUL011826-PA;LFUL001413-PA;LFUL002279-PA;LFUL013520-PA;LFUL004085-PA;LFUL010327-PA;LFUL011827-PA;LFUL018065-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL013953-PA;LFUL000448-PA;LFUL005608-PA;LFUL014805-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL009758-PA;LFUL004900-PA;LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA Reactome: R-HSA-74217 Purine salvage 8 LFUL017374-PA;LFUL011578-PA;LFUL003389-PA;LFUL011577-PA;LFUL017738-PA;LFUL012012-PA;LFUL000108-PA;LFUL004695-PA KEGG: 00970+6.1.1.19 Aminoacyl-tRNA biosynthesis 1 LFUL003958-PA Reactome: R-HSA-5099900 WNT5A-dependent internalization of FZD4 5 LFUL003059-PA;LFUL007491-PA;LFUL000575-PA;LFUL007151-PA;LFUL007853-PA Reactome: R-HSA-209968 Thyroxine biosynthesis 3 LFUL016228-PA;LFUL004593-PA;LFUL003744-PA KEGG: 00680+2.7.1.11 Methane metabolism 2 LFUL011354-PA;LFUL011355-PA Reactome: R-HSA-975577 N-Glycan antennae elongation 5 LFUL005593-PA;LFUL002613-PA;LFUL015715-PA;LFUL003233-PA;LFUL010147-PA KEGG: 00261+2.7.7.4 Monobactam biosynthesis 1 LFUL019316-PA Reactome: R-HSA-975163 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation 4 LFUL005189-PA;LFUL018127-PA;LFUL004537-PA;LFUL018125-PA MetaCyc: PWY-5481 Pyruvate fermentation to (S)-lactate 1 LFUL015394-PA KEGG: 00500+2.7.7.9 Starch and sucrose metabolism 1 LFUL008565-PA MetaCyc: PWY-7592 Arachidonate biosynthesis III (6-desaturase, mammals) 2 LFUL001272-PA;LFUL010698-PA MetaCyc: PWY-7375 Mrna capping I 2 LFUL006150-PA;LFUL000254-PA Reactome: R-HSA-69601 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A 41 LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL010331-PA;LFUL001183-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA;LFUL014805-PA;LFUL005608-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL007901-PA;LFUL013396-PA;LFUL005128-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL003914-PA;LFUL009759-PA;LFUL013254-PA;LFUL012191-PA;LFUL006784-PA Reactome: R-HSA-8964616 G beta:gamma signalling through CDC42 6 LFUL000620-PA;LFUL012255-PA;LFUL000640-PA;LFUL005324-PA;LFUL017104-PA;LFUL003893-PA Reactome: R-HSA-9639288 Amino acids regulate mTORC1 41 LFUL006787-PA;LFUL010662-PA;LFUL013881-PA;LFUL004570-PA;LFUL006212-PA;LFUL018924-PA;LFUL010339-PA;LFUL001193-PA;LFUL009771-PA;LFUL008895-PA;LFUL008406-PA;LFUL006345-PA;LFUL002662-PA;LFUL011021-PA;LFUL009057-PA;LFUL009162-PA;LFUL001914-PA;LFUL010201-PA;LFUL001476-PA;LFUL008957-PA;LFUL012362-PA;LFUL002510-PA;LFUL011204-PA;LFUL003394-PA;LFUL016180-PA;LFUL011203-PA;LFUL011205-PA;LFUL008004-PA;LFUL008994-PA;LFUL013474-PA;LFUL009573-PA;LFUL002108-PA;LFUL015687-PA;LFUL018369-PA;LFUL002663-PA;LFUL001913-PA;LFUL004571-PA;LFUL006140-PA;LFUL006476-PA;LFUL001475-PA;LFUL013473-PA Reactome: R-HSA-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A 51 LFUL014805-PA;LFUL013953-PA;LFUL000448-PA;LFUL005608-PA;LFUL013520-PA;LFUL004085-PA;LFUL010327-PA;LFUL011827-PA;LFUL018065-PA;LFUL017608-PA;LFUL010331-PA;LFUL001183-PA;LFUL001632-PA;LFUL011826-PA;LFUL001413-PA;LFUL002279-PA;LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL009758-PA;LFUL004900-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL003914-PA;LFUL013254-PA;LFUL006784-PA;LFUL006381-PA;LFUL009759-PA;LFUL005128-PA;LFUL008983-PA;LFUL001285-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL015255-PA;LFUL013396-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL007901-PA;LFUL017243-PA;LFUL000664-PA;LFUL016970-PA;LFUL006691-PA;LFUL011394-PA;LFUL003567-PA KEGG: 00030+5.1.3.1 Pentose phosphate pathway 1 LFUL012465-PA Reactome: R-HSA-389960 Formation of tubulin folding intermediates by CCT/TriC 20 LFUL013560-PA;LFUL000920-PA;LFUL004185-PA;LFUL005926-PA;LFUL007016-PA;LFUL014799-PA;LFUL009144-PA;LFUL013557-PA;LFUL004646-PA;LFUL010663-PA;LFUL001282-PA;LFUL003377-PA;LFUL013561-PA;LFUL001283-PA;LFUL014795-PA;LFUL014800-PA;LFUL017103-PA;LFUL014793-PA;LFUL014801-PA;LFUL013555-PA MetaCyc: PWY-4981 L-proline biosynthesis II (from arginine) 1 LFUL014392-PA Reactome: R-HSA-2995383 Initiation of Nuclear Envelope Reformation 3 LFUL004519-PA;LFUL002005-PA;LFUL015121-PA Reactome: R-HSA-162710 Synthesis of glycosylphosphatidylinositol (GPI) 15 LFUL000267-PA;LFUL010474-PA;LFUL008455-PA;LFUL018014-PA;LFUL005976-PA;LFUL008993-PA;LFUL000610-PA;LFUL006006-PA;LFUL010473-PA;LFUL007603-PA;LFUL006272-PA;LFUL000582-PA;LFUL018968-PA;LFUL006341-PA;LFUL008208-PA Reactome: R-HSA-5603041 IRAK4 deficiency (TLR2/4) 1 LFUL018800-PA Reactome: R-HSA-5656121 Translesion synthesis by POLI 14 LFUL014494-PA;LFUL003903-PA;LFUL002760-PA;LFUL004537-PA;LFUL011672-PA;LFUL008688-PA;LFUL000714-PA;LFUL005736-PA;LFUL011669-PA;LFUL011668-PA;LFUL013345-PA;LFUL001437-PA;LFUL006665-PA;LFUL000715-PA Reactome: R-HSA-8941858 Regulation of RUNX3 expression and activity 43 LFUL014805-PA;LFUL009516-PA;LFUL005608-PA;LFUL013520-PA;LFUL010331-PA;LFUL001183-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL001632-PA;LFUL001413-PA;LFUL017218-PA;LFUL017219-PA;LFUL009514-PA;LFUL015402-PA;LFUL011816-PA;LFUL009758-PA;LFUL004900-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL009515-PA;LFUL003914-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL005128-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL004537-PA;LFUL005657-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL015255-PA;LFUL017243-PA;LFUL009513-PA;LFUL000664-PA;LFUL016970-PA KEGG: 00524+2.7.1.1 Neomycin, kanamycin and gentamicin biosynthesis 3 LFUL004281-PA;LFUL004280-PA;LFUL003646-PA MetaCyc: PWY-5041 S-adenosyl-L-methionine cycle II 3 LFUL012283-PA;LFUL008955-PA;LFUL018302-PA MetaCyc: PWY-7218 Photosynthetic 3-hydroxybutanoate biosynthesis (engineered) 2 LFUL001192-PA;LFUL011112-PA Reactome: R-HSA-5419276 Mitochondrial translation termination 65 LFUL006429-PA;LFUL005723-PA;LFUL015276-PA;LFUL000080-PA;LFUL007191-PA;LFUL010234-PA;LFUL008017-PA;LFUL014003-PA;LFUL015537-PA;LFUL012340-PA;LFUL014875-PA;LFUL000320-PA;LFUL007542-PA;LFUL004150-PA;LFUL011340-PA;LFUL007369-PA;LFUL012013-PA;LFUL017678-PA;LFUL005922-PA;LFUL013892-PA;LFUL015233-PA;LFUL002078-PA;LFUL000344-PA;LFUL007193-PA;LFUL004190-PA;LFUL009757-PA;LFUL014538-PA;LFUL010173-PA;LFUL001184-PA;LFUL007188-PA;LFUL017732-PA;LFUL004956-PA;LFUL017828-PA;LFUL003101-PA;LFUL009315-PA;LFUL002976-PA;LFUL009337-PA;LFUL005053-PA;LFUL003376-PA;LFUL001850-PA;LFUL011692-PA;LFUL007667-PA;LFUL005481-PA;LFUL007422-PA;LFUL014313-PA;LFUL004130-PA;LFUL001663-PA;LFUL001538-PA;LFUL017525-PA;LFUL019763-PA;LFUL003929-PA;LFUL004509-PA;LFUL001176-PA;LFUL006854-PA;LFUL007900-PA;LFUL002738-PA;LFUL000878-PA;LFUL010873-PA;LFUL003473-PA;LFUL001323-PA;LFUL004614-PA;LFUL001460-PA;LFUL008019-PA;LFUL007295-PA;LFUL000609-PA Reactome: R-HSA-4411364 Binding of TCF/LEF:CTNNB1 to target gene promoters 2 LFUL005993-PA;LFUL008435-PA MetaCyc: PWY-6689 Trna splicing I 2 LFUL008437-PA;LFUL016205-PA Reactome: R-HSA-163125 Post-translational modification: synthesis of GPI-anchored proteins 1 LFUL010486-PA MetaCyc: PWY-5172 Acetyl-coa biosynthesis III (from citrate) 1 LFUL016366-PA MetaCyc: PWY-6902 Chitin degradation II (Vibrio) 19 LFUL003417-PA;LFUL006704-PA;LFUL007928-PA;LFUL000955-PA;LFUL003460-PA;LFUL003459-PA;LFUL001685-PA;LFUL006590-PA;LFUL000956-PA;LFUL009655-PA;LFUL003457-PA;LFUL003501-PA;LFUL009656-PA;LFUL013525-PA;LFUL015340-PA;LFUL001844-PA;LFUL010999-PA;LFUL010431-PA;LFUL003458-PA Reactome: R-HSA-6787450 tRNA modification in the mitochondrion 8 LFUL002840-PA;LFUL003742-PA;LFUL016637-PA;LFUL011678-PA;LFUL011679-PA;LFUL001536-PA;LFUL006827-PA;LFUL014036-PA MetaCyc: PWY-6857 Retinol biosynthesis 3 LFUL009402-PA;LFUL009398-PA;LFUL009404-PA Reactome: R-HSA-3238698 WNT ligand biogenesis and trafficking 16 LFUL010713-PA;LFUL018894-PA;LFUL014904-PA;LFUL006782-PA;LFUL005535-PA;LFUL008806-PA;LFUL006466-PA;LFUL006781-PA;LFUL008807-PA;LFUL006465-PA;LFUL004541-PA;LFUL009527-PA;LFUL014552-PA;LFUL004540-PA;LFUL004539-PA;LFUL017368-PA Reactome: R-HSA-186797 Signaling by PDGF 3 LFUL009021-PA;LFUL004342-PA;LFUL019569-PA Reactome: R-HSA-9627069 Regulation of the apoptosome activity 7 LFUL001636-PA;LFUL002198-PA;LFUL007046-PA;LFUL014137-PA;LFUL018372-PA;LFUL004784-PA;LFUL016074-PA MetaCyc: PWY-4661 1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza) 4 LFUL019642-PA;LFUL007957-PA;LFUL014713-PA;LFUL014193-PA Reactome: R-HSA-975138 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation 2 LFUL013496-PA;LFUL018800-PA MetaCyc: PWY-7003 Glycerol degradation to butanol 5 LFUL015710-PA;LFUL008549-PA;LFUL005591-PA;LFUL011112-PA;LFUL001192-PA MetaCyc: PWY-6113 Superpathway of mycolate biosynthesis 1 LFUL006083-PA KEGG: 00710+2.7.2.3 Carbon fixation in photosynthetic organisms 1 LFUL008549-PA KEGG: 00250+1.2.1.88 Alanine, aspartate and glutamate metabolism 1 LFUL012268-PA Reactome: R-HSA-76061 RNA Polymerase III Transcription Initiation From Type 1 Promoter 24 LFUL003390-PA;LFUL015757-PA;LFUL005061-PA;LFUL006931-PA;LFUL006422-PA;LFUL010762-PA;LFUL011471-PA;LFUL015504-PA;LFUL010060-PA;LFUL013037-PA;LFUL003284-PA;LFUL010364-PA;LFUL010063-PA;LFUL002481-PA;LFUL001373-PA;LFUL014846-PA;LFUL006932-PA;LFUL010061-PA;LFUL001093-PA;LFUL011294-PA;LFUL000388-PA;LFUL017259-PA;LFUL003911-PA;LFUL014294-PA KEGG: 00062+4.2.1.17+1.1.1.35 Fatty acid elongation 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA KEGG: 00790+4.2.3.12 Folate biosynthesis 1 LFUL010398-PA KEGG: 00450+4.4.1.13 Selenocompound metabolism 2 LFUL013724-PA;LFUL013723-PA KEGG: 00053+1.13.99.1 Ascorbate and aldarate metabolism 1 LFUL005679-PA Reactome: R-HSA-5617833 Cilium Assembly 16 LFUL014799-PA;LFUL017971-PA;LFUL004646-PA;LFUL013557-PA;LFUL010682-PA;LFUL012256-PA;LFUL013560-PA;LFUL014801-PA;LFUL010020-PA;LFUL013555-PA;LFUL010681-PA;LFUL014793-PA;LFUL003377-PA;LFUL013561-PA;LFUL014800-PA;LFUL014795-PA Reactome: R-HSA-9603798 Class I peroxisomal membrane protein import 9 LFUL005295-PA;LFUL018619-PA;LFUL009454-PA;LFUL007854-PA;LFUL002301-PA;LFUL018391-PA;LFUL000576-PA;LFUL002209-PA;LFUL005298-PA MetaCyc: PWY-5451 Acetone degradation I (to methylglyoxal) 2 LFUL019543-PA;LFUL007894-PA MetaCyc: PWY-7379 Mrna capping II 1 LFUL011933-PA Reactome: R-HSA-5678895 Defective CFTR causes cystic fibrosis 46 LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL013277-PA;LFUL007684-PA;LFUL004108-PA;LFUL009774-PA;LFUL005608-PA;LFUL014805-PA;LFUL001413-PA;LFUL001632-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL010331-PA;LFUL001183-PA;LFUL013520-PA;LFUL001157-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL013396-PA;LFUL001667-PA;LFUL007901-PA;LFUL005657-PA;LFUL003567-PA;LFUL013516-PA;LFUL000664-PA;LFUL016970-PA;LFUL009759-PA;LFUL005006-PA;LFUL013254-PA;LFUL007460-PA;LFUL003449-PA;LFUL006784-PA;LFUL003914-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL005128-PA Reactome: R-HSA-8943723 Regulation of PTEN mRNA translation 8 LFUL004232-PA;LFUL015531-PA;LFUL019785-PA;LFUL015532-PA;LFUL019805-PA;LFUL006745-PA;LFUL005454-PA;LFUL006660-PA KEGG: 04150+2.7.11.1 mTOR signaling pathway 50 LFUL006176-PA;LFUL000250-PA;LFUL016685-PA;LFUL000924-PA;LFUL015097-PA;LFUL006336-PA;LFUL003791-PA;LFUL015598-PA;LFUL001467-PA;LFUL010118-PA;LFUL008160-PA;LFUL014180-PA;LFUL012191-PA;LFUL001132-PA;LFUL015132-PA;LFUL019451-PA;LFUL000248-PA;LFUL015336-PA;LFUL003065-PA;LFUL003125-PA;LFUL014316-PA;LFUL005999-PA;LFUL000595-PA;LFUL006936-PA;LFUL014459-PA;LFUL000249-PA;LFUL002766-PA;LFUL018447-PA;LFUL016885-PA;LFUL018448-PA;LFUL001476-PA;LFUL000251-PA;LFUL010552-PA;LFUL000550-PA;LFUL004423-PA;LFUL013749-PA;LFUL004673-PA;LFUL000247-PA;LFUL008438-PA;LFUL006034-PA;LFUL000058-PA;LFUL017285-PA;LFUL016077-PA;LFUL012699-PA;LFUL001475-PA;LFUL004296-PA;LFUL000059-PA;LFUL009466-PA;LFUL010551-PA;LFUL013361-PA MetaCyc: PWY-7182 Linalool biosynthesis I 2 LFUL004955-PA;LFUL011744-PA MetaCyc: PWY-6527 Stachyose degradation 8 LFUL004776-PA;LFUL010337-PA;LFUL015403-PA;LFUL010336-PA;LFUL006901-PA;LFUL015844-PA;LFUL008565-PA;LFUL015843-PA KEGG: 00520+2.6.1.16 Amino sugar and nucleotide sugar metabolism 1 LFUL002889-PA Reactome: R-HSA-1660499 Synthesis of PIPs at the plasma membrane 11 LFUL012051-PA;LFUL018428-PA;LFUL011881-PA;LFUL018426-PA;LFUL012230-PA;LFUL004611-PA;LFUL012052-PA;LFUL017404-PA;LFUL019454-PA;LFUL014130-PA;LFUL008204-PA MetaCyc: PWY-8060 2-deoxy-D-ribose degradation I 1 LFUL012294-PA Reactome: R-HSA-4793954 Defective MOGS causes MOGS-CDG (CDG-2b) 1 LFUL012875-PA Reactome: R-HSA-8866376 Reelin signalling pathway 1 LFUL011104-PA Reactome: R-HSA-68867 Assembly of the pre-replicative complex 16 LFUL019733-PA;LFUL012288-PA;LFUL007817-PA;LFUL015871-PA;LFUL012084-PA;LFUL002734-PA;LFUL012083-PA;LFUL004865-PA;LFUL014586-PA;LFUL014903-PA;LFUL012409-PA;LFUL004598-PA;LFUL009340-PA;LFUL007704-PA;LFUL012130-PA;LFUL006063-PA MetaCyc: PWY-0 Putrescine degradation III 1 LFUL017216-PA MetaCyc: PWY-7826 Amaryllidacea alkaloids biosynthesis 2 LFUL019543-PA;LFUL007894-PA Reactome: R-HSA-1250196 SHC1 events in ERBB2 signaling 1 LFUL018399-PA Reactome: R-HSA-70268 Pyruvate metabolism 4 LFUL015394-PA;LFUL010747-PA;LFUL015126-PA;LFUL008261-PA Reactome: R-HSA-68949 Orc1 removal from chromatin 57 LFUL005608-PA;LFUL014805-PA;LFUL001632-PA;LFUL004598-PA;LFUL015886-PA;LFUL001413-PA;LFUL009340-PA;LFUL013520-PA;LFUL007704-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL009758-PA;LFUL004865-PA;LFUL004900-PA;LFUL012083-PA;LFUL017219-PA;LFUL017218-PA;LFUL014586-PA;LFUL011816-PA;LFUL015402-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL007684-PA;LFUL009774-PA;LFUL015871-PA;LFUL013277-PA;LFUL013254-PA;LFUL006784-PA;LFUL009759-PA;LFUL012130-PA;LFUL006063-PA;LFUL003914-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL014903-PA;LFUL012409-PA;LFUL005128-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL017243-PA;LFUL012288-PA;LFUL019733-PA;LFUL003567-PA;LFUL002734-PA;LFUL007817-PA;LFUL012084-PA;LFUL016970-PA;LFUL000664-PA Reactome: R-HSA-8963901 Chylomicron remodeling 5 LFUL018059-PA;LFUL005945-PA;LFUL018058-PA;LFUL013535-PA;LFUL019397-PA Reactome: R-HSA-1369062 ABC transporters in lipid homeostasis 18 LFUL000502-PA;LFUL000576-PA;LFUL003018-PA;LFUL005298-PA;LFUL012423-PA;LFUL005295-PA;LFUL014014-PA;LFUL000027-PA;LFUL018229-PA;LFUL012421-PA;LFUL018391-PA;LFUL010073-PA;LFUL007026-PA;LFUL000500-PA;LFUL005301-PA;LFUL009871-PA;LFUL010070-PA;LFUL012260-PA MetaCyc: PWY-7112 4-hydroxy-2-nonenal detoxification 8 LFUL016402-PA;LFUL004307-PA;LFUL012058-PA;LFUL012059-PA;LFUL016403-PA;LFUL015031-PA;LFUL003732-PA;LFUL014136-PA MetaCyc: PWY-7858 (5Z)-dodecenoate biosynthesis II 3 LFUL001447-PA;LFUL001448-PA;LFUL006083-PA MetaCyc: PWY-7536 2-amino-3-hydroxycyclopent-2-enone biosynthesis 1 LFUL017816-PA KEGG: 00562+3.1.3.25 Inositol phosphate metabolism 1 LFUL003784-PA Reactome: R-HSA-5684045 Defective ABCD1 causes adrenoleukodystrophy (ALD) 1 LFUL000576-PA Reactome: R-HSA-8964315 G beta:gamma signalling through BTK 5 LFUL000620-PA;LFUL012255-PA;LFUL017104-PA;LFUL003893-PA;LFUL000640-PA MetaCyc: PWY-561 Superpathway of glyoxylate cycle and fatty acid degradation 7 LFUL008263-PA;LFUL017635-PA;LFUL001123-PA;LFUL004114-PA;LFUL004113-PA;LFUL017636-PA;LFUL015809-PA KEGG: 00564+2.3.1.51 Glycerophospholipid metabolism 5 LFUL009878-PA;LFUL008878-PA;LFUL016045-PA;LFUL017634-PA;LFUL002099-PA MetaCyc: PWY-3801 Sucrose degradation II (sucrose synthase) 2 LFUL008565-PA;LFUL001099-PA KEGG: 00232+1.14.14.1 Caffeine metabolism 2 LFUL007894-PA;LFUL019543-PA MetaCyc: PWY-6807 Xyloglucan degradation II (exoglucanase) 7 LFUL012072-PA;LFUL012024-PA;LFUL012258-PA;LFUL006883-PA;LFUL010553-PA;LFUL010555-PA;LFUL010554-PA Reactome: R-HSA-9609523 Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 8 LFUL004545-PA;LFUL014433-PA;LFUL000923-PA;LFUL010677-PA;LFUL014880-PA;LFUL016054-PA;LFUL000515-PA;LFUL002350-PA MetaCyc: PWY-7659 Viridicatumtoxin biosynthesis 2 LFUL004955-PA;LFUL011744-PA KEGG: 00230+2.7.4.6 Purine metabolism 5 LFUL011295-PA;LFUL008636-PA;LFUL017739-PA;LFUL013982-PA;LFUL017852-PA Reactome: R-HSA-5579007 Defective ACY1 causes encephalopathy 1 LFUL007710-PA Reactome: R-HSA-73621 Pyrimidine catabolism 7 LFUL007256-PA;LFUL010923-PA;LFUL006725-PA;LFUL015996-PA;LFUL019532-PA;LFUL005855-PA;LFUL018602-PA KEGG: 00051+5.3.1.6 Fructose and mannose metabolism 1 LFUL005639-PA MetaCyc: PWY-6133 (S)-reticuline biosynthesis II 2 LFUL004047-PA;LFUL004046-PA Reactome: R-HSA-173599 Formation of the active cofactor, UDP-glucuronate 2 LFUL008565-PA;LFUL010590-PA Reactome: R-HSA-381340 Transcriptional regulation of white adipocyte differentiation 35 LFUL006689-PA;LFUL002649-PA;LFUL009542-PA;LFUL000702-PA;LFUL004729-PA;LFUL006641-PA;LFUL004728-PA;LFUL008074-PA;LFUL013287-PA;LFUL005014-PA;LFUL003829-PA;LFUL011231-PA;LFUL008563-PA;LFUL013458-PA;LFUL002120-PA;LFUL018367-PA;LFUL006081-PA;LFUL001163-PA;LFUL001690-PA;LFUL008015-PA;LFUL015835-PA;LFUL008921-PA;LFUL015321-PA;LFUL000453-PA;LFUL005476-PA;LFUL011232-PA;LFUL008073-PA;LFUL018610-PA;LFUL010110-PA;LFUL006789-PA;LFUL003007-PA;LFUL018952-PA;LFUL000701-PA;LFUL009817-PA;LFUL009339-PA KEGG: 00592+3.1.1.32 alpha-Linolenic acid metabolism 1 LFUL015933-PA Reactome: R-HSA-3232118 SUMOylation of transcription factors 1 LFUL002401-PA KEGG: 04070+3.1.3.66 Phosphatidylinositol signaling system 2 LFUL012052-PA;LFUL012051-PA Reactome: R-HSA-6782861 Synthesis of wybutosine at G37 of tRNA(Phe) 5 LFUL015744-PA;LFUL000687-PA;LFUL011912-PA;LFUL003701-PA;LFUL002182-PA MetaCyc: PWY-241 C4 photosynthetic carbon assimilation cycle, NADP-ME type 5 LFUL017492-PA;LFUL012803-PA;LFUL010584-PA;LFUL004391-PA;LFUL012802-PA KEGG: 00520+2.7.1.6 Amino sugar and nucleotide sugar metabolism 3 LFUL004776-PA;LFUL010337-PA;LFUL010336-PA KEGG: 00860+4.1.1.37 Porphyrin and chlorophyll metabolism 1 LFUL000195-PA KEGG: 00720+4.2.1.17+1.1.1.35 Carbon fixation pathways in prokaryotes 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA Reactome: R-HSA-429958 mRNA decay by 3' to 5' exoribonuclease 19 LFUL007322-PA;LFUL015271-PA;LFUL010888-PA;LFUL012106-PA;LFUL015691-PA;LFUL013044-PA;LFUL011544-PA;LFUL018238-PA;LFUL016194-PA;LFUL006413-PA;LFUL017316-PA;LFUL002868-PA;LFUL003231-PA;LFUL017313-PA;LFUL013449-PA;LFUL003227-PA;LFUL016915-PA;LFUL008668-PA;LFUL017317-PA KEGG: 00710+4.1.2.13 Carbon fixation in photosynthetic organisms 1 LFUL011512-PA Reactome: R-HSA-5627123 RHO GTPases activate PAKs 1 LFUL005324-PA MetaCyc: PWY-5891 Menaquinol-11 biosynthesis 2 LFUL006594-PA;LFUL006592-PA Reactome: R-HSA-2173788 Downregulation of TGF-beta receptor signaling 7 LFUL011859-PA;LFUL006251-PA;LFUL014700-PA;LFUL004116-PA;LFUL005953-PA;LFUL004537-PA;LFUL001811-PA Reactome: R-HSA-167243 Tat-mediated HIV elongation arrest and recovery 24 LFUL014608-PA;LFUL003397-PA;LFUL003797-PA;LFUL007672-PA;LFUL010620-PA;LFUL003284-PA;LFUL018856-PA;LFUL013037-PA;LFUL010364-PA;LFUL008825-PA;LFUL006931-PA;LFUL002212-PA;LFUL000398-PA;LFUL016324-PA;LFUL008342-PA;LFUL008550-PA;LFUL004885-PA;LFUL008827-PA;LFUL002536-PA;LFUL001415-PA;LFUL016326-PA;LFUL001373-PA;LFUL008343-PA;LFUL006932-PA Reactome: R-HSA-975634 Retinoid metabolism and transport 20 LFUL010843-PA;LFUL016033-PA;LFUL018059-PA;LFUL013535-PA;LFUL002624-PA;LFUL019397-PA;LFUL019491-PA;LFUL005814-PA;LFUL016032-PA;LFUL002721-PA;LFUL016031-PA;LFUL012592-PA;LFUL005945-PA;LFUL002722-PA;LFUL002720-PA;LFUL002623-PA;LFUL016034-PA;LFUL016035-PA;LFUL018058-PA;LFUL009642-PA Reactome: R-HSA-399956 CRMPs in Sema3A signaling 1 LFUL010552-PA KEGG: 00500+2.4.1.15 Starch and sucrose metabolism 2 LFUL015612-PA;LFUL012953-PA MetaCyc: PWY-7980 ATP biosynthesis 5 LFUL014557-PA;LFUL016356-PA;LFUL003394-PA;LFUL006212-PA;LFUL014559-PA Reactome: R-HSA-5610785 GLI3 is processed to GLI3R by the proteasome 43 LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL005128-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL003914-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL004537-PA;LFUL005657-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL015255-PA;LFUL017243-PA;LFUL015886-PA;LFUL001632-PA;LFUL001413-PA;LFUL008156-PA;LFUL013520-PA;LFUL001183-PA;LFUL010331-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL010552-PA;LFUL005608-PA;LFUL014805-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL009758-PA;LFUL004900-PA;LFUL017218-PA;LFUL017219-PA;LFUL015402-PA;LFUL011816-PA KEGG: 00053+3.1.1.17 Ascorbate and aldarate metabolism 2 LFUL001189-PA;LFUL004102-PA MetaCyc: PWY-7197 Pyrimidine deoxyribonucleotide phosphorylation 8 LFUL003582-PA;LFUL005981-PA;LFUL013982-PA;LFUL017739-PA;LFUL017852-PA;LFUL005983-PA;LFUL011295-PA;LFUL008636-PA Reactome: R-HSA-72165 mRNA Splicing - Minor Pathway 35 LFUL006074-PA;LFUL000564-PA;LFUL008410-PA;LFUL009060-PA;LFUL010238-PA;LFUL008689-PA;LFUL001105-PA;LFUL008827-PA;LFUL002035-PA;LFUL006595-PA;LFUL001373-PA;LFUL003378-PA;LFUL005950-PA;LFUL010620-PA;LFUL018856-PA;LFUL011233-PA;LFUL008825-PA;LFUL016290-PA;LFUL017484-PA;LFUL011935-PA;LFUL019480-PA;LFUL017230-PA;LFUL008550-PA;LFUL016599-PA;LFUL009321-PA;LFUL006932-PA;LFUL000483-PA;LFUL002815-PA;LFUL003284-PA;LFUL013037-PA;LFUL004058-PA;LFUL010364-PA;LFUL000565-PA;LFUL001998-PA;LFUL006931-PA MetaCyc: PWY-7337 10-cis-heptadecenoyl-CoA degradation (yeast) 2 LFUL001447-PA;LFUL001448-PA KEGG: 00983+2.5.1.18 Drug metabolism - other enzymes 2 LFUL014136-PA;LFUL004307-PA KEGG: 00270+1.13.11.20 Cysteine and methionine metabolism 2 LFUL001559-PA;LFUL001560-PA MetaCyc: PWY-3581 (S)-reticuline biosynthesis I 2 LFUL004047-PA;LFUL004046-PA Reactome: R-HSA-5601884 PIWI-interacting RNA (piRNA) biogenesis 12 LFUL006215-PA;LFUL008550-PA;LFUL002947-PA;LFUL010364-PA;LFUL010620-PA;LFUL003284-PA;LFUL013037-PA;LFUL006931-PA;LFUL011405-PA;LFUL001373-PA;LFUL019823-PA;LFUL006932-PA MetaCyc: PWY-7779 Methyl tert-butyl ether degradation 3 LFUL018646-PA;LFUL017943-PA;LFUL012393-PA Reactome: R-HSA-73843 5-Phosphoribose 1-diphosphate biosynthesis 1 LFUL006506-PA Reactome: R-HSA-77346 Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA 1 LFUL017943-PA Reactome: R-HSA-5674499 Negative feedback regulation of MAPK pathway 1 LFUL014137-PA MetaCyc: PWY-7619 Juniperonate biosynthesis 18 LFUL001272-PA;LFUL001095-PA;LFUL017948-PA;LFUL007078-PA;LFUL013816-PA;LFUL013817-PA;LFUL012360-PA;LFUL004766-PA;LFUL015422-PA;LFUL013818-PA;LFUL006533-PA;LFUL002423-PA;LFUL012361-PA;LFUL012359-PA;LFUL013814-PA;LFUL010698-PA;LFUL013815-PA;LFUL015420-PA MetaCyc: PWY-7456 Beta-(1,4)-mannan degradation 2 LFUL000192-PA;LFUL006253-PA Reactome: R-HSA-2022857 Keratan sulfate degradation 6 LFUL001685-PA;LFUL003459-PA;LFUL003457-PA;LFUL007928-PA;LFUL003458-PA;LFUL003460-PA MetaCyc: PWY-6558 Heparan sulfate biosynthesis (late stages) 5 LFUL004864-PA;LFUL003070-PA;LFUL001319-PA;LFUL003068-PA;LFUL003069-PA Reactome: R-HSA-164843 2-LTR circle formation 4 LFUL005423-PA;LFUL002949-PA;LFUL002948-PA;LFUL001094-PA MetaCyc: PWY-7606 Docosahexaenoate biosynthesis III (6-desaturase, mammals) 7 LFUL018646-PA;LFUL001272-PA;LFUL010698-PA;LFUL012393-PA;LFUL001447-PA;LFUL001448-PA;LFUL017943-PA Reactome: R-HSA-1236978 Cross-presentation of soluble exogenous antigens (endosomes) 39 LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL009758-PA;LFUL004900-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL014805-PA;LFUL005608-PA;LFUL013520-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL001183-PA;LFUL010331-PA;LFUL001632-PA;LFUL001413-PA;LFUL015255-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL005657-PA;LFUL017243-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL003914-PA;LFUL013254-PA;LFUL006784-PA;LFUL009759-PA;LFUL005128-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA Reactome: R-HSA-8873719 RAB geranylgeranylation 7 LFUL011881-PA;LFUL016215-PA;LFUL017209-PA;LFUL016785-PA;LFUL004517-PA;LFUL001380-PA;LFUL017992-PA Reactome: R-HSA-937072 TRAF6-mediated induction of TAK1 complex within TLR4 complex 5 LFUL018125-PA;LFUL004537-PA;LFUL018127-PA;LFUL005189-PA;LFUL014668-PA Reactome: R-HSA-5676590 NIK-->noncanonical NF-kB signaling 44 LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL017243-PA;LFUL015255-PA;LFUL007901-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL005128-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA;LFUL016470-PA;LFUL003914-PA;LFUL009759-PA;LFUL001478-PA;LFUL013254-PA;LFUL006784-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA;LFUL015886-PA;LFUL014805-PA;LFUL002709-PA;LFUL005608-PA Reactome: R-HSA-1483226 Synthesis of PI 1 LFUL002586-PA Reactome: R-HSA-156902 Peptide chain elongation 75 LFUL001176-PA;LFUL004636-PA;LFUL004420-PA;LFUL002950-PA;LFUL015920-PA;LFUL016069-PA;LFUL006902-PA;LFUL011563-PA;LFUL004637-PA;LFUL008330-PA;LFUL006788-PA;LFUL018996-PA;LFUL009487-PA;LFUL016060-PA;LFUL016059-PA;LFUL012852-PA;LFUL012372-PA;LFUL010697-PA;LFUL005171-PA;LFUL010275-PA;LFUL015591-PA;LFUL001717-PA;LFUL000695-PA;LFUL006688-PA;LFUL003221-PA;LFUL018450-PA;LFUL006255-PA;LFUL019500-PA;LFUL009485-PA;LFUL000050-PA;LFUL005935-PA;LFUL013851-PA;LFUL017436-PA;LFUL010852-PA;LFUL011000-PA;LFUL004418-PA;LFUL001329-PA;LFUL004537-PA;LFUL002673-PA;LFUL003261-PA;LFUL018772-PA;LFUL015696-PA;LFUL002925-PA;LFUL014304-PA;LFUL008661-PA;LFUL010862-PA;LFUL008669-PA;LFUL017447-PA;LFUL004596-PA;LFUL007452-PA;LFUL006093-PA;LFUL014225-PA;LFUL006675-PA;LFUL019701-PA;LFUL011123-PA;LFUL014007-PA;LFUL002249-PA;LFUL019054-PA;LFUL008016-PA;LFUL003947-PA;LFUL006720-PA;LFUL012271-PA;LFUL004974-PA;LFUL018953-PA;LFUL001102-PA;LFUL001681-PA;LFUL002208-PA;LFUL017656-PA;LFUL011278-PA;LFUL014893-PA;LFUL017793-PA;LFUL007358-PA;LFUL009630-PA;LFUL007583-PA;LFUL012702-PA Reactome: R-HSA-380284 Loss of proteins required for interphase microtubule organization from the centrosome 17 LFUL004460-PA;LFUL003889-PA;LFUL009096-PA;LFUL018303-PA;LFUL010041-PA;LFUL014621-PA;LFUL009757-PA;LFUL010789-PA;LFUL009638-PA;LFUL011516-PA;LFUL001762-PA;LFUL017541-PA;LFUL002675-PA;LFUL015517-PA;LFUL004301-PA;LFUL007649-PA;LFUL015311-PA KEGG: 00590+1.14.99.1 Arachidonic acid metabolism 1 LFUL002455-PA Reactome: R-HSA-5655302 Signaling by FGFR1 in disease 3 LFUL019436-PA;LFUL008510-PA;LFUL014291-PA MetaCyc: PWY-5278 Sulfite oxidation III 1 LFUL019316-PA KEGG: 00970+6.3.5.7 Aminoacyl-tRNA biosynthesis 9 LFUL008916-PA;LFUL001742-PA;LFUL005575-PA;LFUL016050-PA;LFUL016051-PA;LFUL008915-PA;LFUL001747-PA;LFUL001748-PA;LFUL008054-PA KEGG: 00640+1.2.1.27 Propanoate metabolism 1 LFUL014148-PA KEGG: 00230+2.7.4.6+2.7.4.3 Purine metabolism 2 LFUL005981-PA;LFUL005983-PA MetaCyc: PWY-7234 Inosine-5'-phosphate biosynthesis III 4 LFUL015685-PA;LFUL015684-PA;LFUL001229-PA;LFUL017018-PA Reactome: R-HSA-8868766 rRNA processing in the mitochondrion 3 LFUL005951-PA;LFUL003742-PA;LFUL006827-PA Reactome: R-HSA-450302 activated TAK1 mediates p38 MAPK activation 5 LFUL009466-PA;LFUL005189-PA;LFUL018127-PA;LFUL004537-PA;LFUL018125-PA Reactome: R-HSA-977347 Serine biosynthesis 1 LFUL012864-PA Reactome: R-HSA-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) 9 LFUL002813-PA;LFUL019546-PA;LFUL011800-PA;LFUL014701-PA;LFUL002812-PA;LFUL019547-PA;LFUL000557-PA;LFUL002811-PA;LFUL011801-PA MetaCyc: PWY-5138 Fatty acid beta-oxidation IV (unsaturated, even number) 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA KEGG: 00561+2.3.1.51 Glycerolipid metabolism 5 LFUL009878-PA;LFUL008878-PA;LFUL016045-PA;LFUL002099-PA;LFUL017634-PA Reactome: R-HSA-3000157 Laminin interactions 6 LFUL010340-PA;LFUL009021-PA;LFUL002806-PA;LFUL002807-PA;LFUL005332-PA;LFUL019569-PA Reactome: R-HSA-428359 Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA 1 LFUL005583-PA KEGG: 00230+2.4.2.1 Purine metabolism 2 LFUL011577-PA;LFUL011578-PA MetaCyc: PWY-6987 Lipoate biosynthesis and incorporation III (Bacillus) 5 LFUL008960-PA;LFUL004145-PA;LFUL004144-PA;LFUL003022-PA;LFUL002318-PA MetaCyc: PWY-7856 Heme a biosynthesis 1 LFUL015294-PA Reactome: R-HSA-1483191 Synthesis of PC 11 LFUL006473-PA;LFUL011020-PA;LFUL007162-PA;LFUL015300-PA;LFUL001619-PA;LFUL012259-PA;LFUL008159-PA;LFUL001917-PA;LFUL015299-PA;LFUL011019-PA;LFUL006383-PA KEGG: 00380+4.2.1.17+1.1.1.35 Tryptophan metabolism 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA Reactome: R-HSA-936837 Ion transport by P-type ATPases 34 LFUL014159-PA;LFUL019365-PA;LFUL006995-PA;LFUL006994-PA;LFUL001083-PA;LFUL003634-PA;LFUL000068-PA;LFUL003687-PA;LFUL007282-PA;LFUL012866-PA;LFUL000381-PA;LFUL015334-PA;LFUL018829-PA;LFUL012254-PA;LFUL016210-PA;LFUL001084-PA;LFUL009789-PA;LFUL016208-PA;LFUL015324-PA;LFUL012628-PA;LFUL006996-PA;LFUL010258-PA;LFUL011922-PA;LFUL018938-PA;LFUL001082-PA;LFUL014409-PA;LFUL018830-PA;LFUL003688-PA;LFUL017521-PA;LFUL018828-PA;LFUL011921-PA;LFUL016209-PA;LFUL002885-PA;LFUL007283-PA Reactome: R-HSA-451308 Activation of Ca-permeable Kainate Receptor 1 LFUL018841-PA Reactome: R-HSA-75953 RNA Polymerase II Transcription Initiation 35 LFUL006931-PA;LFUL017944-PA;LFUL004554-PA;LFUL016337-PA;LFUL004052-PA;LFUL006416-PA;LFUL014212-PA;LFUL015240-PA;LFUL010364-PA;LFUL003284-PA;LFUL013037-PA;LFUL004050-PA;LFUL014887-PA;LFUL006932-PA;LFUL000689-PA;LFUL008550-PA;LFUL010456-PA;LFUL010467-PA;LFUL014888-PA;LFUL016703-PA;LFUL004051-PA;LFUL013957-PA;LFUL018855-PA;LFUL019760-PA;LFUL015513-PA;LFUL008825-PA;LFUL010620-PA;LFUL018856-PA;LFUL001373-PA;LFUL005318-PA;LFUL010468-PA;LFUL008827-PA;LFUL013636-PA;LFUL003393-PA;LFUL016338-PA MetaCyc: PWY-6367 D-myo-inositol-5-phosphate metabolism 9 LFUL015148-PA;LFUL014591-PA;LFUL001462-PA;LFUL016455-PA;LFUL014147-PA;LFUL001109-PA;LFUL006197-PA;LFUL006196-PA;LFUL001461-PA Reactome: R-HSA-210991 Basigin interactions 1 LFUL003571-PA KEGG: 00073+2.3.1.20 Cutin, suberine and wax biosynthesis 3 LFUL002264-PA;LFUL001220-PA;LFUL000328-PA MetaCyc: PWY-6482 Diphthamide biosynthesis I (archaea) 4 LFUL015678-PA;LFUL000574-PA;LFUL014729-PA;LFUL015679-PA KEGG: 00030+5.3.1.6 Pentose phosphate pathway 1 LFUL005639-PA Reactome: R-HSA-5673001 RAF/MAP kinase cascade 7 LFUL006796-PA;LFUL009416-PA;LFUL010848-PA;LFUL014137-PA;LFUL018841-PA;LFUL010847-PA;LFUL002885-PA Reactome: R-HSA-420092 Glucagon-type ligand receptors 5 LFUL012255-PA;LFUL000620-PA;LFUL000640-PA;LFUL003893-PA;LFUL017104-PA Reactome: R-HSA-163765 ChREBP activates metabolic gene expression 5 LFUL005606-PA;LFUL005724-PA;LFUL005055-PA;LFUL006083-PA;LFUL016366-PA MetaCyc: PWY-5109 Fermentation to 2-methylbutanoate 3 LFUL012393-PA;LFUL017943-PA;LFUL018646-PA KEGG: 00720+1.1.1.37 Carbon fixation pathways in prokaryotes 3 LFUL004114-PA;LFUL004113-PA;LFUL015809-PA KEGG: 00730+2.7.4.3 Thiamine metabolism 9 LFUL008697-PA;LFUL005981-PA;LFUL000260-PA;LFUL012071-PA;LFUL009370-PA;LFUL003006-PA;LFUL005983-PA;LFUL006106-PA;LFUL000226-PA KEGG: 00565+3.1.4.4 Ether lipid metabolism 1 LFUL009158-PA Reactome: R-HSA-9614657 FOXO-mediated transcription of cell death genes 5 LFUL008074-PA;LFUL008073-PA;LFUL013749-PA;LFUL001175-PA;LFUL015112-PA KEGG: 00401+2.6.1.1 Novobiocin biosynthesis 2 LFUL011379-PA;LFUL003406-PA Reactome: R-HSA-2395516 Electron transport from NADPH to Ferredoxin 2 LFUL003519-PA;LFUL007911-PA KEGG: 00627+4.2.1.17 Aminobenzoate degradation 3 LFUL012393-PA;LFUL017943-PA;LFUL018646-PA Reactome: R-HSA-167172 Transcription of the HIV genome 35 LFUL004052-PA;LFUL016337-PA;LFUL006416-PA;LFUL014212-PA;LFUL015240-PA;LFUL010364-PA;LFUL004050-PA;LFUL013037-PA;LFUL003284-PA;LFUL006931-PA;LFUL017944-PA;LFUL004554-PA;LFUL008550-PA;LFUL000689-PA;LFUL010456-PA;LFUL014888-PA;LFUL010467-PA;LFUL014887-PA;LFUL006932-PA;LFUL018855-PA;LFUL019760-PA;LFUL015513-PA;LFUL008825-PA;LFUL010620-PA;LFUL018856-PA;LFUL004051-PA;LFUL016703-PA;LFUL013957-PA;LFUL008827-PA;LFUL013636-PA;LFUL003393-PA;LFUL016338-PA;LFUL001373-PA;LFUL005318-PA;LFUL010468-PA Reactome: R-HSA-5083630 Defective LFNG causes SCDO3 2 LFUL006223-PA;LFUL018752-PA Reactome: R-HSA-193048 Androgen biosynthesis 1 LFUL009957-PA MetaCyc: PWY-2221 Entner-Doudoroff pathway III (semi-phosphorylative) 4 LFUL011112-PA;LFUL001192-PA;LFUL004102-PA;LFUL001189-PA Reactome: R-HSA-380972 Energy dependent regulation of mTOR by LKB1-AMPK 22 LFUL004580-PA;LFUL010339-PA;LFUL001193-PA;LFUL011021-PA;LFUL009057-PA;LFUL004570-PA;LFUL012362-PA;LFUL016180-PA;LFUL001476-PA;LFUL004571-PA;LFUL006140-PA;LFUL013749-PA;LFUL012151-PA;LFUL009573-PA;LFUL002108-PA;LFUL005590-PA;LFUL008160-PA;LFUL006345-PA;LFUL001585-PA;LFUL006171-PA;LFUL004581-PA;LFUL001475-PA MetaCyc: PWY-7791 UMP biosynthesis III 7 LFUL006715-PA;LFUL014037-PA;LFUL014039-PA;LFUL006717-PA;LFUL014041-PA;LFUL014042-PA;LFUL014040-PA Reactome: R-HSA-8964208 Phenylalanine metabolism 2 LFUL004045-PA;LFUL004768-PA KEGG: 00330+2.7.2.11+1.2.1.41 Arginine and proline metabolism 1 LFUL013157-PA KEGG: 00250+3.5.1.2 Alanine, aspartate and glutamate metabolism 1 LFUL003072-PA Reactome: R-HSA-70350 Fructose catabolism 2 LFUL018837-PA;LFUL016507-PA Reactome: R-HSA-2022928 HS-GAG biosynthesis 12 LFUL015478-PA;LFUL016067-PA;LFUL001319-PA;LFUL003068-PA;LFUL009642-PA;LFUL010840-PA;LFUL003069-PA;LFUL005814-PA;LFUL002623-PA;LFUL003070-PA;LFUL002624-PA;LFUL004864-PA MetaCyc: PWY-7852 6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium) 2 LFUL019539-PA;LFUL004602-PA MetaCyc: PWY-7340 9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast) 2 LFUL001447-PA;LFUL001448-PA Reactome: R-HSA-112382 Formation of RNA Pol II elongation complex 43 LFUL007352-PA;LFUL008342-PA;LFUL016324-PA;LFUL004531-PA;LFUL010850-PA;LFUL004208-PA;LFUL003397-PA;LFUL015513-PA;LFUL008825-PA;LFUL010620-PA;LFUL018856-PA;LFUL008343-PA;LFUL001373-PA;LFUL008815-PA;LFUL002536-PA;LFUL004921-PA;LFUL010468-PA;LFUL013636-PA;LFUL008827-PA;LFUL003393-PA;LFUL002527-PA;LFUL000564-PA;LFUL002212-PA;LFUL006931-PA;LFUL000398-PA;LFUL016449-PA;LFUL004554-PA;LFUL003797-PA;LFUL006416-PA;LFUL014608-PA;LFUL010364-PA;LFUL000565-PA;LFUL014212-PA;LFUL007672-PA;LFUL013037-PA;LFUL003284-PA;LFUL016326-PA;LFUL001415-PA;LFUL006932-PA;LFUL004885-PA;LFUL008550-PA;LFUL010456-PA;LFUL010467-PA Reactome: R-HSA-174048 APC/C:Cdc20 mediated degradation of Cyclin B 12 LFUL013953-PA;LFUL000448-PA;LFUL006381-PA;LFUL004537-PA;LFUL011394-PA;LFUL002279-PA;LFUL011826-PA;LFUL004085-PA;LFUL008983-PA;LFUL001285-PA;LFUL011827-PA;LFUL006691-PA KEGG: 00010+2.7.1.11 Glycolysis / Gluconeogenesis 2 LFUL011354-PA;LFUL011355-PA MetaCyc: PWY-7420 Monoacylglycerol metabolism (yeast) 1 LFUL011856-PA KEGG: 00513+2.4.1.261 Various types of N-glycan biosynthesis 1 LFUL004439-PA Reactome: R-HSA-425366 Transport of bile salts and organic acids, metal ions and amine compounds 5 LFUL006383-PA;LFUL015300-PA;LFUL005039-PA;LFUL015299-PA;LFUL001917-PA Reactome: R-HSA-8935964 RUNX1 regulates expression of components of tight junctions 5 LFUL009514-PA;LFUL009516-PA;LFUL007567-PA;LFUL009513-PA;LFUL009515-PA Reactome: R-HSA-416476 G alpha (q) signalling events 25 LFUL012255-PA;LFUL000646-PA;LFUL000647-PA;LFUL006196-PA;LFUL002137-PA;LFUL000620-PA;LFUL011364-PA;LFUL014130-PA;LFUL001446-PA;LFUL010575-PA;LFUL000645-PA;LFUL003791-PA;LFUL017763-PA;LFUL016095-PA;LFUL008845-PA;LFUL006197-PA;LFUL016376-PA;LFUL014147-PA;LFUL001779-PA;LFUL014180-PA;LFUL000640-PA;LFUL003893-PA;LFUL017104-PA;LFUL010285-PA;LFUL003538-PA KEGG: 00513+2.4.1.68 Various types of N-glycan biosynthesis 1 LFUL011017-PA KEGG: 00030+3.1.1.31 Pentose phosphate pathway 1 LFUL009918-PA MetaCyc: PWY-7007 Methyl ketone biosynthesis (engineered) 5 LFUL018646-PA;LFUL001447-PA;LFUL017943-PA;LFUL001448-PA;LFUL012393-PA Reactome: R-HSA-8866652 Synthesis of active ubiquitin: roles of E1 and E2 enzymes 2 LFUL004537-PA;LFUL008562-PA Reactome: R-HSA-165159 mTOR signalling 15 LFUL001475-PA;LFUL006443-PA;LFUL001476-PA;LFUL016180-PA;LFUL012362-PA;LFUL006345-PA;LFUL004570-PA;LFUL009057-PA;LFUL002108-PA;LFUL011021-PA;LFUL009573-PA;LFUL006140-PA;LFUL004571-PA;LFUL001193-PA;LFUL010339-PA MetaCyc: PWY-6672 Cis-genanyl-coa degradation 2 LFUL006868-PA;LFUL001222-PA Reactome: R-HSA-1614558 Degradation of cysteine and homocysteine 4 LFUL001927-PA;LFUL001560-PA;LFUL001559-PA;LFUL011342-PA KEGG: 00604+3.2.1.52 Glycosphingolipid biosynthesis - ganglio series 11 LFUL003417-PA;LFUL006704-PA;LFUL007928-PA;LFUL003457-PA;LFUL015340-PA;LFUL003460-PA;LFUL001685-PA;LFUL003459-PA;LFUL010431-PA;LFUL003458-PA;LFUL006590-PA Reactome: R-HSA-168271 Transport of Ribonucleoproteins into the Host Nucleus 22 LFUL002666-PA;LFUL015687-PA;LFUL006282-PA;LFUL005156-PA;LFUL013801-PA;LFUL009840-PA;LFUL018131-PA;LFUL000581-PA;LFUL010864-PA;LFUL005565-PA;LFUL016880-PA;LFUL011549-PA;LFUL000200-PA;LFUL006358-PA;LFUL005157-PA;LFUL009303-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL016186-PA;LFUL002533-PA;LFUL008059-PA Reactome: R-HSA-9615017 FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes 3 LFUL000159-PA;LFUL019446-PA;LFUL008336-PA KEGG: 00562+2.7.1.67 Inositol phosphate metabolism 3 LFUL018426-PA;LFUL018428-PA;LFUL017404-PA Reactome: R-HSA-4755583 Defective DOLK causes DOLK-CDG (CDG-1m) 1 LFUL006417-PA Reactome: R-HSA-69541 Stabilization of p53 2 LFUL004537-PA;LFUL006936-PA Reactome: R-HSA-445355 Smooth Muscle Contraction 8 LFUL015597-PA;LFUL003623-PA;LFUL004588-PA;LFUL016952-PA;LFUL004589-PA;LFUL015110-PA;LFUL004592-PA;LFUL015596-PA Reactome: R-HSA-5609978 Defective GALT can cause Galactosemia 1 LFUL015403-PA MetaCyc: PWY-6936 Seleno-amino acid biosynthesis (plants) 2 LFUL013724-PA;LFUL013723-PA KEGG: 00430+2.3.2.2 Taurine and hypotaurine metabolism 6 LFUL003732-PA;LFUL015031-PA;LFUL016402-PA;LFUL016403-PA;LFUL012059-PA;LFUL012058-PA Reactome: R-HSA-390651 Dopamine receptors 1 LFUL001628-PA Reactome: R-HSA-388479 Vasopressin-like receptors 2 LFUL016376-PA;LFUL002137-PA Reactome: R-HSA-352238 Breakdown of the nuclear lamina 1 LFUL003920-PA Reactome: R-HSA-2024101 CS/DS degradation 6 LFUL003459-PA;LFUL001685-PA;LFUL003457-PA;LFUL007928-PA;LFUL003458-PA;LFUL003460-PA Reactome: R-HSA-5362517 Signaling by Retinoic Acid 3 LFUL008261-PA;LFUL010747-PA;LFUL016974-PA KEGG: 00030+2.7.1.11 Pentose phosphate pathway 2 LFUL011354-PA;LFUL011355-PA Reactome: R-HSA-5218921 VEGFR2 mediated cell proliferation 4 LFUL000924-PA;LFUL001806-PA;LFUL009249-PA;LFUL009246-PA MetaCyc: PWY-6908 Thiamine diphosphate biosynthesis IV (eukaryotes) 1 LFUL006365-PA Reactome: R-HSA-1839117 Signaling by cytosolic FGFR1 fusion mutants 3 LFUL014291-PA;LFUL008510-PA;LFUL019436-PA KEGG: 00860+4.2.1.75 Porphyrin and chlorophyll metabolism 1 LFUL011432-PA Reactome: R-HSA-2029485 Role of phospholipids in phagocytosis 6 LFUL005920-PA;LFUL001462-PA;LFUL018399-PA;LFUL009246-PA;LFUL009158-PA;LFUL009249-PA Reactome: R-HSA-6794361 Neurexins and neuroligins 7 LFUL010847-PA;LFUL005799-PA;LFUL010848-PA;LFUL016177-PA;LFUL009803-PA;LFUL000705-PA;LFUL005782-PA MetaCyc: PWY-8040 Ansatrienin biosynthesis 1 LFUL007185-PA Reactome: R-HSA-5250924 B-WICH complex positively regulates rRNA expression 21 LFUL010552-PA;LFUL009752-PA;LFUL000106-PA;LFUL002481-PA;LFUL001373-PA;LFUL011953-PA;LFUL001835-PA;LFUL001785-PA;LFUL006932-PA;LFUL010061-PA;LFUL003284-PA;LFUL013037-PA;LFUL004058-PA;LFUL010060-PA;LFUL001784-PA;LFUL010364-PA;LFUL004763-PA;LFUL006931-PA;LFUL003875-PA;LFUL011954-PA;LFUL001836-PA MetaCyc: PWY-5739 GDP-D-perosamine biosynthesis 1 LFUL002512-PA Reactome: R-HSA-5666185 RHO GTPases Activate Rhotekin and Rhophilins 2 LFUL004287-PA;LFUL004492-PA KEGG: 00052+2.7.1.1 Galactose metabolism 3 LFUL004280-PA;LFUL003646-PA;LFUL004281-PA MetaCyc: PWY-6627 Salinosporamide A biosynthesis 2 LFUL011577-PA;LFUL011578-PA KEGG: 00770+3.6.1.9 Pantothenate and CoA biosynthesis 2 LFUL014206-PA;LFUL000002-PA Reactome: R-HSA-5684264 MAP3K8 (TPL2)-dependent MAPK1/3 activation 4 LFUL016470-PA;LFUL004537-PA;LFUL010280-PA;LFUL015886-PA KEGG: 00720+4.2.1.2 Carbon fixation pathways in prokaryotes 2 LFUL017635-PA;LFUL017636-PA KEGG: 00300+4.3.3.7 Lysine biosynthesis 1 LFUL009128-PA MetaCyc: PWY-5132 Lupulone and humulone biosynthesis 2 LFUL001222-PA;LFUL006868-PA KEGG: 00660+6.2.1.5 C5-Branched dibasic acid metabolism 4 LFUL006472-PA;LFUL016366-PA;LFUL004029-PA;LFUL005914-PA Reactome: R-HSA-9646399 Aggrephagy 22 LFUL004646-PA;LFUL013557-PA;LFUL010682-PA;LFUL014799-PA;LFUL005006-PA;LFUL012256-PA;LFUL006593-PA;LFUL013560-PA;LFUL008718-PA;LFUL013555-PA;LFUL004537-PA;LFUL010020-PA;LFUL014801-PA;LFUL014793-PA;LFUL010681-PA;LFUL013561-PA;LFUL003377-PA;LFUL000787-PA;LFUL016557-PA;LFUL014800-PA;LFUL014795-PA;LFUL001537-PA Reactome: R-HSA-1483255 PI Metabolism 1 LFUL011144-PA Reactome: R-HSA-4641257 Degradation of AXIN 46 LFUL003567-PA;LFUL016970-PA;LFUL000664-PA;LFUL004665-PA;LFUL017243-PA;LFUL004537-PA;LFUL001667-PA;LFUL013396-PA;LFUL005657-PA;LFUL007901-PA;LFUL015255-PA;LFUL004666-PA;LFUL012889-PA;LFUL019638-PA;LFUL015825-PA;LFUL017408-PA;LFUL005128-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL003914-PA;LFUL010441-PA;LFUL003913-PA;LFUL012888-PA;LFUL011817-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL004900-PA;LFUL009758-PA;LFUL012890-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL001413-PA;LFUL001632-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL018065-PA;LFUL017608-PA;LFUL000173-PA;LFUL013520-PA;LFUL005608-PA;LFUL014805-PA Reactome: R-HSA-76071 RNA Polymerase III Transcription Initiation From Type 3 Promoter 24 LFUL003390-PA;LFUL000035-PA;LFUL006931-PA;LFUL011471-PA;LFUL010762-PA;LFUL009113-PA;LFUL011565-PA;LFUL012358-PA;LFUL010060-PA;LFUL013037-PA;LFUL003284-PA;LFUL010364-PA;LFUL015295-PA;LFUL002481-PA;LFUL002583-PA;LFUL014846-PA;LFUL001373-PA;LFUL006932-PA;LFUL010061-PA;LFUL011294-PA;LFUL000388-PA;LFUL017259-PA;LFUL003911-PA;LFUL014294-PA KEGG: 00130+2.1.1.163 Ubiquinone and other terpenoid-quinone biosynthesis 2 LFUL006594-PA;LFUL006592-PA Reactome: R-HSA-2173789 TGF-beta receptor signaling activates SMADs 1 LFUL011859-PA MetaCyc: PWY-6855 Chitin degradation I (archaea) 10 LFUL000956-PA;LFUL009918-PA;LFUL010999-PA;LFUL001844-PA;LFUL005858-PA;LFUL013525-PA;LFUL000955-PA;LFUL009656-PA;LFUL003501-PA;LFUL009655-PA Reactome: R-HSA-2672351 Stimuli-sensing channels 35 LFUL004847-PA;LFUL009201-PA;LFUL004874-PA;LFUL000790-PA;LFUL009411-PA;LFUL018172-PA;LFUL010618-PA;LFUL009200-PA;LFUL013487-PA;LFUL019020-PA;LFUL018074-PA;LFUL013486-PA;LFUL004433-PA;LFUL005958-PA;LFUL007919-PA;LFUL001868-PA;LFUL007150-PA;LFUL013354-PA;LFUL001381-PA;LFUL006217-PA;LFUL009412-PA;LFUL005143-PA;LFUL004537-PA;LFUL017769-PA;LFUL000066-PA;LFUL008662-PA;LFUL012780-PA;LFUL002522-PA;LFUL004846-PA;LFUL012879-PA;LFUL003076-PA;LFUL012366-PA;LFUL008419-PA;LFUL001382-PA;LFUL006218-PA Reactome: R-HSA-6791055 TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P 1 LFUL002759-PA Reactome: R-HSA-112308 Presynaptic depolarization and calcium channel opening 5 LFUL013366-PA;LFUL013791-PA;LFUL002969-PA;LFUL011490-PA;LFUL011488-PA Reactome: R-HSA-72695 Formation of the ternary complex, and subsequently, the 43S complex 47 LFUL001937-PA;LFUL001717-PA;LFUL006688-PA;LFUL002208-PA;LFUL001681-PA;LFUL014893-PA;LFUL005636-PA;LFUL013851-PA;LFUL006720-PA;LFUL012271-PA;LFUL003947-PA;LFUL001102-PA;LFUL005935-PA;LFUL002211-PA;LFUL009630-PA;LFUL004418-PA;LFUL002324-PA;LFUL010852-PA;LFUL017793-PA;LFUL010424-PA;LFUL011000-PA;LFUL012702-PA;LFUL009762-PA;LFUL006445-PA;LFUL017288-PA;LFUL015920-PA;LFUL018772-PA;LFUL001176-PA;LFUL004420-PA;LFUL002925-PA;LFUL000390-PA;LFUL015341-PA;LFUL004636-PA;LFUL004637-PA;LFUL001962-PA;LFUL006788-PA;LFUL011563-PA;LFUL004229-PA;LFUL018996-PA;LFUL006873-PA;LFUL015591-PA;LFUL006675-PA;LFUL012852-PA;LFUL019701-PA;LFUL016059-PA;LFUL005171-PA;LFUL014007-PA Reactome: R-HSA-5656169 Termination of translesion DNA synthesis 21 LFUL004537-PA;LFUL007960-PA;LFUL003903-PA;LFUL011672-PA;LFUL005720-PA;LFUL011668-PA;LFUL005736-PA;LFUL010253-PA;LFUL006982-PA;LFUL001437-PA;LFUL002760-PA;LFUL007279-PA;LFUL014494-PA;LFUL007277-PA;LFUL019536-PA;LFUL004599-PA;LFUL009325-PA;LFUL013345-PA;LFUL011669-PA;LFUL008688-PA;LFUL006665-PA Reactome: R-HSA-5619107 Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) 22 LFUL011549-PA;LFUL005157-PA;LFUL000200-PA;LFUL006358-PA;LFUL005565-PA;LFUL016880-PA;LFUL010864-PA;LFUL000581-PA;LFUL016186-PA;LFUL002533-PA;LFUL008059-PA;LFUL009303-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL002666-PA;LFUL009840-PA;LFUL018131-PA;LFUL013801-PA;LFUL005156-PA;LFUL015687-PA;LFUL006282-PA Reactome: R-HSA-6798695 Neutrophil degranulation 104 LFUL017488-PA;LFUL005006-PA;LFUL012072-PA;LFUL012294-PA;LFUL006784-PA;LFUL001653-PA;LFUL007594-PA;LFUL004957-PA;LFUL004260-PA;LFUL009236-PA;LFUL013097-PA;LFUL017408-PA;LFUL019638-PA;LFUL004825-PA;LFUL004185-PA;LFUL016177-PA;LFUL001193-PA;LFUL012173-PA;LFUL009771-PA;LFUL015255-PA;LFUL007901-PA;LFUL018198-PA;LFUL009755-PA;LFUL019474-PA;LFUL002948-PA;LFUL009064-PA;LFUL006877-PA;LFUL003389-PA;LFUL005717-PA;LFUL003507-PA;LFUL014252-PA;LFUL018065-PA;LFUL010227-PA;LFUL010331-PA;LFUL012024-PA;LFUL004900-PA;LFUL009162-PA;LFUL002678-PA;LFUL019530-PA;LFUL000593-PA;LFUL008899-PA;LFUL011944-PA;LFUL006498-PA;LFUL003505-PA;LFUL014880-PA;LFUL004259-PA;LFUL006014-PA;LFUL013690-PA;LFUL000429-PA;LFUL008797-PA;LFUL009705-PA;LFUL000328-PA;LFUL003990-PA;LFUL006278-PA;LFUL006883-PA;LFUL007858-PA;LFUL018372-PA;LFUL003653-PA;LFUL002917-PA;LFUL007664-PA;LFUL011881-PA;LFUL013396-PA;LFUL001667-PA;LFUL013171-PA;LFUL014142-PA;LFUL004695-PA;LFUL001099-PA;LFUL015334-PA;LFUL005608-PA;LFUL012351-PA;LFUL002108-PA;LFUL011578-PA;LFUL016074-PA;LFUL012355-PA;LFUL015596-PA;LFUL011577-PA;LFUL009425-PA;LFUL010621-PA;LFUL019446-PA;LFUL014512-PA;LFUL011803-PA;LFUL002276-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL015597-PA;LFUL009057-PA;LFUL010970-PA;LFUL002949-PA;LFUL015023-PA;LFUL007319-PA;LFUL013709-PA;LFUL017103-PA;LFUL008785-PA;LFUL011652-PA;LFUL011741-PA;LFUL010441-PA;LFUL007835-PA;LFUL009164-PA;LFUL007162-PA;LFUL013277-PA;LFUL007684-PA;LFUL006425-PA;LFUL016366-PA Reactome: R-HSA-182218 Nef Mediated CD8 Down-regulation 6 LFUL011204-PA;LFUL000575-PA;LFUL011203-PA;LFUL007491-PA;LFUL011205-PA;LFUL007853-PA KEGG: 00071+4.2.1.17+1.1.1.211 Fatty acid degradation 1 LFUL017943-PA KEGG: 00623+1.1.1.35 Toluene degradation 3 LFUL018646-PA;LFUL017943-PA;LFUL012393-PA KEGG: 00670+2.1.1.45 One carbon pool by folate 2 LFUL002258-PA;LFUL002259-PA Reactome: R-HSA-72689 Formation of a pool of free 40S subunits 87 LFUL004418-PA;LFUL011000-PA;LFUL010852-PA;LFUL003261-PA;LFUL002673-PA;LFUL006445-PA;LFUL004537-PA;LFUL001329-PA;LFUL009485-PA;LFUL019500-PA;LFUL006255-PA;LFUL018450-PA;LFUL003221-PA;LFUL006688-PA;LFUL000695-PA;LFUL001717-PA;LFUL017436-PA;LFUL013851-PA;LFUL005935-PA;LFUL000050-PA;LFUL016060-PA;LFUL009487-PA;LFUL006873-PA;LFUL018996-PA;LFUL010275-PA;LFUL015591-PA;LFUL005171-PA;LFUL010697-PA;LFUL012852-PA;LFUL012372-PA;LFUL016059-PA;LFUL016069-PA;LFUL015920-PA;LFUL002950-PA;LFUL004420-PA;LFUL015341-PA;LFUL004636-PA;LFUL001176-PA;LFUL001962-PA;LFUL006788-PA;LFUL008330-PA;LFUL004637-PA;LFUL011563-PA;LFUL006902-PA;LFUL009630-PA;LFUL002324-PA;LFUL007358-PA;LFUL017793-PA;LFUL010424-PA;LFUL012702-PA;LFUL009762-PA;LFUL007583-PA;LFUL017288-PA;LFUL001937-PA;LFUL019054-PA;LFUL011278-PA;LFUL014893-PA;LFUL005636-PA;LFUL002208-PA;LFUL017656-PA;LFUL001681-PA;LFUL001102-PA;LFUL018953-PA;LFUL006720-PA;LFUL012271-PA;LFUL004974-PA;LFUL003947-PA;LFUL008016-PA;LFUL004229-PA;LFUL014225-PA;LFUL006093-PA;LFUL002249-PA;LFUL014007-PA;LFUL006675-PA;LFUL011123-PA;LFUL019701-PA;LFUL008661-PA;LFUL002925-PA;LFUL014304-PA;LFUL000390-PA;LFUL015696-PA;LFUL018772-PA;LFUL004596-PA;LFUL007452-PA;LFUL017447-PA;LFUL008669-PA;LFUL010862-PA MetaCyc: PWY-7383 Anaerobic energy metabolism (invertebrates, cytosol) 8 LFUL003406-PA;LFUL007185-PA;LFUL004114-PA;LFUL001192-PA;LFUL010175-PA;LFUL011379-PA;LFUL004113-PA;LFUL015809-PA Reactome: R-HSA-912446 Meiotic recombination 15 LFUL005173-PA;LFUL004270-PA;LFUL012609-PA;LFUL007471-PA;LFUL007486-PA;LFUL004632-PA;LFUL007979-PA;LFUL001126-PA;LFUL005736-PA;LFUL006936-PA;LFUL010680-PA;LFUL010792-PA;LFUL001437-PA;LFUL004631-PA;LFUL016724-PA KEGG: 00051+2.7.1.11 Fructose and mannose metabolism 2 LFUL011355-PA;LFUL011354-PA Reactome: R-HSA-167161 HIV Transcription Initiation 35 LFUL000689-PA;LFUL008550-PA;LFUL010456-PA;LFUL010467-PA;LFUL014888-PA;LFUL014887-PA;LFUL006932-PA;LFUL016337-PA;LFUL004052-PA;LFUL006416-PA;LFUL014212-PA;LFUL015240-PA;LFUL010364-PA;LFUL003284-PA;LFUL013037-PA;LFUL004050-PA;LFUL006931-PA;LFUL017944-PA;LFUL004554-PA;LFUL013636-PA;LFUL008827-PA;LFUL003393-PA;LFUL016338-PA;LFUL001373-PA;LFUL005318-PA;LFUL010468-PA;LFUL018855-PA;LFUL019760-PA;LFUL015513-PA;LFUL008825-PA;LFUL018856-PA;LFUL010620-PA;LFUL004051-PA;LFUL016703-PA;LFUL013957-PA Reactome: R-HSA-8941856 RUNX3 regulates NOTCH signaling 6 LFUL008074-PA;LFUL005551-PA;LFUL001836-PA;LFUL008073-PA;LFUL001835-PA;LFUL016227-PA Reactome: R-HSA-8939211 ESR-mediated signaling 4 LFUL005424-PA;LFUL014299-PA;LFUL014137-PA;LFUL014303-PA MetaCyc: PWY-8047 Bryostatin biosynthesis 1 LFUL006083-PA KEGG: 00480+1.17.4.1 Glutathione metabolism 19 LFUL014063-PA;LFUL019252-PA;LFUL014941-PA;LFUL008033-PA;LFUL015842-PA;LFUL005848-PA;LFUL003861-PA;LFUL006960-PA;LFUL019261-PA;LFUL013124-PA;LFUL017179-PA;LFUL001680-PA;LFUL008100-PA;LFUL019301-PA;LFUL004087-PA;LFUL013859-PA;LFUL004400-PA;LFUL018976-PA;LFUL016612-PA Reactome: R-HSA-399719 Trafficking of AMPA receptors 3 LFUL018841-PA;LFUL019442-PA;LFUL002885-PA Reactome: R-HSA-5603037 IRAK4 deficiency (TLR5) 1 LFUL018800-PA Reactome: R-HSA-9664565 Signaling by ERBB2 KD Mutants 1 LFUL010369-PA MetaCyc: PWY-6644 Fluoroacetate and fluorothreonine biosynthesis 2 LFUL011578-PA;LFUL011577-PA Reactome: R-HSA-4570464 SUMOylation of RNA binding proteins 22 LFUL015687-PA;LFUL006282-PA;LFUL005156-PA;LFUL013801-PA;LFUL018131-PA;LFUL009840-PA;LFUL002666-PA;LFUL013881-PA;LFUL002532-PA;LFUL009305-PA;LFUL009303-PA;LFUL002533-PA;LFUL008059-PA;LFUL016186-PA;LFUL000581-PA;LFUL010864-PA;LFUL016880-PA;LFUL005565-PA;LFUL000200-PA;LFUL005157-PA;LFUL006358-PA;LFUL011549-PA KEGG: 00010+5.1.3.3 Glycolysis / Gluconeogenesis 1 LFUL002992-PA Reactome: R-HSA-8941326 RUNX2 regulates bone development 4 LFUL009514-PA;LFUL009516-PA;LFUL009513-PA;LFUL009515-PA Reactome: R-HSA-1483213 Synthesis of PE 4 LFUL001619-PA;LFUL011031-PA;LFUL011019-PA;LFUL011020-PA KEGG: 00230+2.7.4.3 Purine metabolism 9 LFUL006106-PA;LFUL000226-PA;LFUL005983-PA;LFUL009370-PA;LFUL003006-PA;LFUL012071-PA;LFUL000260-PA;LFUL005981-PA;LFUL008697-PA Reactome: R-HSA-8875656 MET receptor recycling 2 LFUL004517-PA;LFUL002707-PA Reactome: R-HSA-212436 Generic Transcription Pathway 24 LFUL006689-PA;LFUL001690-PA;LFUL009542-PA;LFUL015321-PA;LFUL008921-PA;LFUL013968-PA;LFUL000702-PA;LFUL011232-PA;LFUL004729-PA;LFUL018610-PA;LFUL006789-PA;LFUL010110-PA;LFUL004728-PA;LFUL013287-PA;LFUL003007-PA;LFUL005014-PA;LFUL009817-PA;LFUL000701-PA;LFUL011231-PA;LFUL013458-PA;LFUL015327-PA;LFUL009339-PA;LFUL001163-PA;LFUL018367-PA Reactome: R-HSA-427601 Multifunctional anion exchangers 3 LFUL010846-PA;LFUL000193-PA;LFUL009396-PA Reactome: R-HSA-933543 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 1 LFUL010280-PA KEGG: 00785+6.3.1.20 Lipoic acid metabolism 1 LFUL003022-PA Reactome: R-HSA-204626 Hypusine synthesis from eIF5A-lysine 2 LFUL010589-PA;LFUL010233-PA MetaCyc: PWY-6799 Fatty acid biosynthesis initiation (plant mitochondria) 1 LFUL006083-PA Reactome: R-HSA-69231 Cyclin D associated events in G1 12 LFUL002485-PA;LFUL013765-PA;LFUL010468-PA;LFUL000101-PA;LFUL015886-PA;LFUL010250-PA;LFUL006416-PA;LFUL010251-PA;LFUL002340-PA;LFUL004537-PA;LFUL010467-PA;LFUL010456-PA Reactome: R-HSA-8948216 Collagen chain trimerization 5 LFUL000176-PA;LFUL013341-PA;LFUL009021-PA;LFUL008274-PA;LFUL019569-PA MetaCyc: PWY-7723 Bacterial bioluminescence 1 LFUL006083-PA MetaCyc: PWY-1622 Formaldehyde assimilation I (serine pathway) 8 LFUL015809-PA;LFUL004113-PA;LFUL001565-PA;LFUL004114-PA;LFUL004544-PA;LFUL011112-PA;LFUL008386-PA;LFUL009609-PA Reactome: R-HSA-447043 Neurofascin interactions 1 LFUL002336-PA KEGG: 00030+4.1.2.4 Pentose phosphate pathway 1 LFUL012294-PA Reactome: R-HSA-202670 ERKs are inactivated 1 LFUL014137-PA KEGG: 00983+2.7.4.14 Drug metabolism - other enzymes 1 LFUL006106-PA KEGG: 04070+2.7.8.11 Phosphatidylinositol signaling system 1 LFUL002586-PA Reactome: R-HSA-9017802 Noncanonical activation of NOTCH3 4 LFUL008785-PA;LFUL005973-PA;LFUL018390-PA;LFUL003906-PA Reactome: R-HSA-2028269 Signaling by Hippo 3 LFUL007567-PA;LFUL011230-PA;LFUL003065-PA Reactome: R-HSA-5632928 Defective Mismatch Repair Associated With MSH2 1 LFUL000900-PA MetaCyc: PWY-5530 Sorbitol biosynthesis II 2 LFUL001189-PA;LFUL004102-PA Reactome: R-HSA-72764 Eukaryotic Translation Termination 77 LFUL008669-PA;LFUL017447-PA;LFUL010862-PA;LFUL007452-PA;LFUL004596-PA;LFUL015696-PA;LFUL014304-PA;LFUL002925-PA;LFUL018772-PA;LFUL008661-PA;LFUL014007-PA;LFUL019701-PA;LFUL006675-PA;LFUL011123-PA;LFUL002249-PA;LFUL006093-PA;LFUL014225-PA;LFUL018953-PA;LFUL001102-PA;LFUL003947-PA;LFUL008016-PA;LFUL004974-PA;LFUL012271-PA;LFUL006720-PA;LFUL011278-PA;LFUL014893-PA;LFUL001681-PA;LFUL017656-PA;LFUL002208-PA;LFUL019054-PA;LFUL007583-PA;LFUL003488-PA;LFUL012702-PA;LFUL017793-PA;LFUL009630-PA;LFUL007358-PA;LFUL006902-PA;LFUL011563-PA;LFUL006788-PA;LFUL004637-PA;LFUL008330-PA;LFUL004636-PA;LFUL004420-PA;LFUL001176-PA;LFUL015920-PA;LFUL016069-PA;LFUL002950-PA;LFUL010697-PA;LFUL005171-PA;LFUL016059-PA;LFUL012852-PA;LFUL012372-PA;LFUL015591-PA;LFUL010275-PA;LFUL009487-PA;LFUL018996-PA;LFUL016060-PA;LFUL000050-PA;LFUL005935-PA;LFUL013851-PA;LFUL017436-PA;LFUL006688-PA;LFUL001717-PA;LFUL016822-PA;LFUL000695-PA;LFUL006255-PA;LFUL019500-PA;LFUL009485-PA;LFUL018450-PA;LFUL003221-PA;LFUL001329-PA;LFUL002673-PA;LFUL003261-PA;LFUL004537-PA;LFUL011000-PA;LFUL010852-PA;LFUL004418-PA Reactome: R-HSA-1834949 Cytosolic sensors of pathogen-associated DNA 21 LFUL006931-PA;LFUL003390-PA;LFUL004631-PA;LFUL011471-PA;LFUL010762-PA;LFUL010364-PA;LFUL003284-PA;LFUL013037-PA;LFUL002949-PA;LFUL010060-PA;LFUL001373-PA;LFUL014846-PA;LFUL002481-PA;LFUL010061-PA;LFUL006932-PA;LFUL003911-PA;LFUL014294-PA;LFUL017259-PA;LFUL002948-PA;LFUL004632-PA;LFUL000388-PA Reactome: R-HSA-418885 DCC mediated attractive signaling 2 LFUL005324-PA;LFUL003791-PA Reactome: R-HSA-71262 Carnitine synthesis 2 LFUL014296-PA;LFUL007321-PA KEGG: 00565+3.1.1.47 Ether lipid metabolism 2 LFUL006702-PA;LFUL012539-PA MetaCyc: PWY-7838 Globo-series glycosphingolipids biosynthesis 1 LFUL014857-PA Reactome: R-HSA-1227986 Signaling by ERBB2 1 LFUL010369-PA Reactome: R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 14 LFUL014908-PA;LFUL016095-PA;LFUL014909-PA;LFUL018059-PA;LFUL005945-PA;LFUL013535-PA;LFUL002086-PA;LFUL019397-PA;LFUL001330-PA;LFUL017984-PA;LFUL018058-PA;LFUL002553-PA;LFUL001624-PA;LFUL010285-PA MetaCyc: PWY-66 GDP-L-fucose biosynthesis I (from GDP-D-mannose) 1 LFUL002512-PA Reactome: R-HSA-1663150 The activation of arylsulfatases 2 LFUL008412-PA;LFUL008414-PA Reactome: R-HSA-400253 Circadian Clock 17 LFUL008073-PA;LFUL014700-PA;LFUL015886-PA;LFUL000172-PA;LFUL015835-PA;LFUL019818-PA;LFUL019815-PA;LFUL018367-PA;LFUL012911-PA;LFUL019822-PA;LFUL006251-PA;LFUL011779-PA;LFUL004537-PA;LFUL016740-PA;LFUL016741-PA;LFUL011778-PA;LFUL008074-PA MetaCyc: PWY-7279 Aerobic respiration II (cytochrome c) (yeast) 3 LFUL001123-PA;LFUL009172-PA;LFUL008263-PA Reactome: R-HSA-189200 Cellular hexose transport 23 LFUL008982-PA;LFUL007292-PA;LFUL008427-PA;LFUL017625-PA;LFUL019464-PA;LFUL011829-PA;LFUL005013-PA;LFUL003411-PA;LFUL007536-PA;LFUL003413-PA;LFUL003414-PA;LFUL014604-PA;LFUL003409-PA;LFUL003410-PA;LFUL008429-PA;LFUL001990-PA;LFUL005570-PA;LFUL012026-PA;LFUL004107-PA;LFUL003408-PA;LFUL003412-PA;LFUL007293-PA;LFUL003415-PA Reactome: R-HSA-72731 Recycling of eIF2:GDP 3 LFUL015888-PA;LFUL018466-PA;LFUL002211-PA Reactome: R-HSA-180910 Vpr-mediated nuclear import of PICs 22 LFUL016186-PA;LFUL008059-PA;LFUL002533-PA;LFUL009303-PA;LFUL009305-PA;LFUL002532-PA;LFUL013881-PA;LFUL016880-PA;LFUL005565-PA;LFUL011549-PA;LFUL000200-PA;LFUL006358-PA;LFUL005157-PA;LFUL000581-PA;LFUL010864-PA;LFUL013801-PA;LFUL009840-PA;LFUL018131-PA;LFUL015687-PA;LFUL006282-PA;LFUL005156-PA;LFUL002666-PA Reactome: R-HSA-5610787 Hedgehog 'off' state 16 LFUL016392-PA;LFUL011026-PA;LFUL004973-PA;LFUL004880-PA;LFUL002151-PA;LFUL014754-PA;LFUL008741-PA;LFUL008080-PA;LFUL000754-PA;LFUL002509-PA;LFUL015154-PA;LFUL008156-PA;LFUL011025-PA;LFUL006192-PA;LFUL008742-PA;LFUL010531-PA MetaCyc: PWY-6840 Homoglutathione biosynthesis 2 LFUL019657-PA;LFUL008713-PA KEGG: 00220+3.5.1.2 Arginine biosynthesis 1 LFUL003072-PA KEGG: 00190+7.1.2.2 Oxidative phosphorylation 5 LFUL014557-PA;LFUL016356-PA;LFUL003394-PA;LFUL006212-PA;LFUL014559-PA Reactome: R-HSA-499943 Interconversion of nucleotide di- and triphosphates 37 LFUL014941-PA;LFUL002259-PA;LFUL014063-PA;LFUL003025-PA;LFUL019261-PA;LFUL005983-PA;LFUL003861-PA;LFUL006960-PA;LFUL004087-PA;LFUL002258-PA;LFUL005981-PA;LFUL019301-PA;LFUL001680-PA;LFUL003006-PA;LFUL016612-PA;LFUL013982-PA;LFUL018976-PA;LFUL004400-PA;LFUL008636-PA;LFUL019252-PA;LFUL000260-PA;LFUL003026-PA;LFUL012071-PA;LFUL009370-PA;LFUL000226-PA;LFUL005848-PA;LFUL015842-PA;LFUL008033-PA;LFUL008697-PA;LFUL003582-PA;LFUL013859-PA;LFUL008100-PA;LFUL013124-PA;LFUL017179-PA;LFUL006399-PA;LFUL006106-PA;LFUL007664-PA KEGG: 00901+2.7.1.222 Indole alkaloid biosynthesis 12 LFUL008577-PA;LFUL016788-PA;LFUL017515-PA;LFUL017514-PA;LFUL011077-PA;LFUL003119-PA;LFUL001435-PA;LFUL016065-PA;LFUL014877-PA;LFUL002420-PA;LFUL006589-PA;LFUL017513-PA Reactome: R-HSA-163359 Glucagon signaling in metabolic regulation 10 LFUL010531-PA;LFUL003893-PA;LFUL004880-PA;LFUL008742-PA;LFUL000620-PA;LFUL000640-PA;LFUL000754-PA;LFUL012255-PA;LFUL014754-PA;LFUL008741-PA KEGG: 00250+2.6.1.16 Alanine, aspartate and glutamate metabolism 1 LFUL002889-PA MetaCyc: PWY-5353 Arachidonate biosynthesis I (6-desaturase, lower eukaryotes) 2 LFUL010698-PA;LFUL001272-PA Reactome: R-HSA-1855191 Synthesis of IPs in the nucleus 2 LFUL019642-PA;LFUL014713-PA MetaCyc: PWY-6733 Sporopollenin precursors biosynthesis 18 LFUL013656-PA;LFUL013655-PA;LFUL010157-PA;LFUL013658-PA;LFUL008789-PA;LFUL018767-PA;LFUL012819-PA;LFUL012816-PA;LFUL013657-PA;LFUL012811-PA;LFUL012818-PA;LFUL018766-PA;LFUL012814-PA;LFUL012820-PA;LFUL012813-PA;LFUL010158-PA;LFUL002995-PA;LFUL012817-PA KEGG: 00590+3.1.1.4 Arachidonic acid metabolism 20 LFUL013309-PA;LFUL019491-PA;LFUL016033-PA;LFUL013307-PA;LFUL010843-PA;LFUL013311-PA;LFUL013308-PA;LFUL004585-PA;LFUL012016-PA;LFUL002720-PA;LFUL016034-PA;LFUL016035-PA;LFUL016031-PA;LFUL012592-PA;LFUL016032-PA;LFUL016881-PA;LFUL002721-PA;LFUL002722-PA;LFUL011621-PA;LFUL013310-PA Reactome: R-HSA-69091 Polymerase switching 15 LFUL007804-PA;LFUL008688-PA;LFUL013345-PA;LFUL011668-PA;LFUL011669-PA;LFUL001174-PA;LFUL002178-PA;LFUL006665-PA;LFUL014494-PA;LFUL002760-PA;LFUL007960-PA;LFUL003903-PA;LFUL009032-PA;LFUL011672-PA;LFUL005720-PA Reactome: R-HSA-9665251 Resistance of ERBB2 KD mutants to lapatinib 1 LFUL010369-PA KEGG: 00310+1.2.4.2 Lysine degradation 5 LFUL006666-PA;LFUL003936-PA;LFUL003940-PA;LFUL006667-PA;LFUL003935-PA MetaCyc: PWY-6398 Melatonin degradation I 2 LFUL019543-PA;LFUL007894-PA MetaCyc: PWY-5668 Cardiolipin biosynthesis I 2 LFUL014211-PA;LFUL001902-PA Reactome: R-HSA-195399 VEGF binds to VEGFR leading to receptor dimerization 2 LFUL006738-PA;LFUL006737-PA Reactome: R-HSA-390918 Peroxisomal lipid metabolism 1 LFUL010581-PA Reactome: R-HSA-156590 Glutathione conjugation 3 LFUL014136-PA;LFUL017391-PA;LFUL009335-PA KEGG: 00740+3.6.1.9 Riboflavin metabolism 2 LFUL000002-PA;LFUL014206-PA Reactome: R-HSA-3214847 HATs acetylate histones 60 LFUL015760-PA;LFUL015853-PA;LFUL013851-PA;LFUL018836-PA;LFUL000689-PA;LFUL011402-PA;LFUL013833-PA;LFUL018913-PA;LFUL015505-PA;LFUL005368-PA;LFUL012677-PA;LFUL018073-PA;LFUL000376-PA;LFUL019717-PA;LFUL008341-PA;LFUL012345-PA;LFUL002544-PA;LFUL001835-PA;LFUL008992-PA;LFUL008074-PA;LFUL015240-PA;LFUL002794-PA;LFUL001286-PA;LFUL004098-PA;LFUL009631-PA;LFUL000658-PA;LFUL004489-PA;LFUL006231-PA;LFUL012344-PA;LFUL011401-PA;LFUL013887-PA;LFUL016629-PA;LFUL015854-PA;LFUL012676-PA;LFUL002686-PA;LFUL014004-PA;LFUL015692-PA;LFUL005366-PA;LFUL017434-PA;LFUL000519-PA;LFUL002546-PA;LFUL011400-PA;LFUL004097-PA;LFUL000058-PA;LFUL008073-PA;LFUL000059-PA;LFUL003848-PA;LFUL003060-PA;LFUL017078-PA;LFUL012092-PA;LFUL006229-PA;LFUL018912-PA;LFUL005367-PA;LFUL015690-PA;LFUL008275-PA;LFUL002298-PA;LFUL001836-PA;LFUL004653-PA;LFUL005654-PA;LFUL006279-PA Reactome: R-HSA-5358493 Synthesis of diphthamide-EEF2 6 LFUL015678-PA;LFUL015030-PA;LFUL008272-PA;LFUL000574-PA;LFUL014729-PA;LFUL015679-PA Reactome: R-HSA-68616 Assembly of the ORC complex at the origin of replication 5 LFUL012083-PA;LFUL014903-PA;LFUL012409-PA;LFUL002734-PA;LFUL012084-PA KEGG: 00240+3.1.3.89 Pyrimidine metabolism 1 LFUL011037-PA MetaCyc: PWY-5394 Betalamic acid biosynthesis 2 LFUL004047-PA;LFUL004046-PA KEGG: 00720+2.3.3.8 Carbon fixation pathways in prokaryotes 1 LFUL016366-PA Reactome: R-HSA-3000484 Scavenging by Class F Receptors 5 LFUL013535-PA;LFUL019397-PA;LFUL018059-PA;LFUL005945-PA;LFUL018058-PA MetaCyc: PWY-7625 Phosphatidylinositol biosynthesis II (eukaryotes) 1 LFUL002586-PA Reactome: R-HSA-8875555 MET activates RAP1 and RAC1 1 LFUL002707-PA Reactome: R-HSA-2514853 Condensation of Prometaphase Chromosomes 12 LFUL017215-PA;LFUL006469-PA;LFUL006468-PA;LFUL007162-PA;LFUL014386-PA;LFUL019478-PA;LFUL018115-PA;LFUL017764-PA;LFUL017214-PA;LFUL011584-PA;LFUL017213-PA;LFUL011339-PA Reactome: R-HSA-202733 Cell surface interactions at the vascular wall 10 LFUL012742-PA;LFUL013535-PA;LFUL019397-PA;LFUL018058-PA;LFUL013097-PA;LFUL005814-PA;LFUL012739-PA;LFUL012744-PA;LFUL005945-PA;LFUL018059-PA Reactome: R-HSA-450341 Activation of the AP-1 family of transcription factors 2 LFUL014137-PA;LFUL014905-PA MetaCyc: PWY-5744 Glyoxylate assimilation 8 LFUL017492-PA;LFUL010442-PA;LFUL012803-PA;LFUL009296-PA;LFUL012802-PA;LFUL004391-PA;LFUL010584-PA;LFUL005606-PA Reactome: R-HSA-5689880 Ub-specific processing proteases 71 LFUL016970-PA;LFUL011154-PA;LFUL015240-PA;LFUL017175-PA;LFUL005657-PA;LFUL001667-PA;LFUL013396-PA;LFUL000800-PA;LFUL012544-PA;LFUL017243-PA;LFUL005128-PA;LFUL013254-PA;LFUL014502-PA;LFUL009759-PA;LFUL018303-PA;LFUL011349-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL006279-PA;LFUL007684-PA;LFUL013277-PA;LFUL012890-PA;LFUL009758-PA;LFUL017219-PA;LFUL011816-PA;LFUL013413-PA;LFUL001413-PA;LFUL008562-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL014196-PA;LFUL005608-PA;LFUL013189-PA;LFUL014805-PA;LFUL003567-PA;LFUL018125-PA;LFUL000664-PA;LFUL004665-PA;LFUL004666-PA;LFUL015255-PA;LFUL004537-PA;LFUL007901-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL012889-PA;LFUL018871-PA;LFUL006784-PA;LFUL018127-PA;LFUL003914-PA;LFUL018836-PA;LFUL004061-PA;LFUL009125-PA;LFUL012888-PA;LFUL009774-PA;LFUL013808-PA;LFUL017118-PA;LFUL004900-PA;LFUL017218-PA;LFUL015402-PA;LFUL001632-PA;LFUL000119-PA;LFUL000059-PA;LFUL000058-PA;LFUL013520-PA;LFUL000173-PA;LFUL018065-PA;LFUL010331-PA;LFUL003942-PA KEGG: 00230+2.7.1.40 Purine metabolism 1 LFUL001192-PA Reactome: R-HSA-9640463 Wax biosynthesis 18 LFUL013657-PA;LFUL012816-PA;LFUL018766-PA;LFUL012818-PA;LFUL012811-PA;LFUL012813-PA;LFUL012814-PA;LFUL012820-PA;LFUL012817-PA;LFUL002995-PA;LFUL010158-PA;LFUL013655-PA;LFUL013656-PA;LFUL013658-PA;LFUL010157-PA;LFUL008789-PA;LFUL012819-PA;LFUL018767-PA KEGG: 00220+3.5.1.14 Arginine biosynthesis 1 LFUL007710-PA Reactome: R-HSA-198753 ERK/MAPK targets 1 LFUL014137-PA Reactome: R-HSA-375281 Hormone ligand-binding receptors 1 LFUL001779-PA Reactome: R-HSA-437239 Recycling pathway of L1 19 LFUL013561-PA;LFUL003377-PA;LFUL002704-PA;LFUL014795-PA;LFUL014800-PA;LFUL013555-PA;LFUL010020-PA;LFUL014801-PA;LFUL014793-PA;LFUL010681-PA;LFUL012256-PA;LFUL013560-PA;LFUL004646-PA;LFUL010682-PA;LFUL013557-PA;LFUL014799-PA;LFUL000575-PA;LFUL007491-PA;LFUL007853-PA Reactome: R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling 3 LFUL018148-PA;LFUL018149-PA;LFUL004537-PA Reactome: R-HSA-5625740 RHO GTPases activate PKNs 5 LFUL013894-PA;LFUL013893-PA;LFUL015328-PA;LFUL001813-PA;LFUL000924-PA MetaCyc: PWY-3722 Glycine betaine biosynthesis II (Gram-positive bacteria) 1 LFUL008143-PA MetaCyc: PWY-6363 D-myo-inositol (1,4,5)-trisphosphate degradation 2 LFUL009747-PA;LFUL003784-PA Reactome: R-HSA-8856828 Clathrin-mediated endocytosis 24 LFUL005511-PA;LFUL002676-PA;LFUL000240-PA;LFUL003059-PA;LFUL019397-PA;LFUL013535-PA;LFUL013808-PA;LFUL018059-PA;LFUL007319-PA;LFUL014734-PA;LFUL004537-PA;LFUL018058-PA;LFUL000199-PA;LFUL015508-PA;LFUL002535-PA;LFUL008204-PA;LFUL005945-PA;LFUL007853-PA;LFUL013420-PA;LFUL016812-PA;LFUL005095-PA;LFUL007491-PA;LFUL000575-PA;LFUL006478-PA KEGG: 00900+3.4.24.84 Terpenoid backbone biosynthesis 1 LFUL016506-PA Reactome: R-HSA-77588 SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs 6 LFUL003133-PA;LFUL009060-PA;LFUL000565-PA;LFUL016290-PA;LFUL016599-PA;LFUL000564-PA Reactome: R-HSA-4755579 Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ 1 LFUL009957-PA Reactome: R-HSA-5655862 Translesion synthesis by POLK 15 LFUL006665-PA;LFUL000715-PA;LFUL001437-PA;LFUL011669-PA;LFUL005736-PA;LFUL011668-PA;LFUL013345-PA;LFUL008688-PA;LFUL000714-PA;LFUL019536-PA;LFUL011672-PA;LFUL003903-PA;LFUL002760-PA;LFUL004537-PA;LFUL014494-PA Reactome: R-HSA-2393930 Phosphate bond hydrolysis by NUDT proteins 4 LFUL002924-PA;LFUL019034-PA;LFUL018775-PA;LFUL018776-PA Reactome: R-HSA-375276 Peptide ligand-binding receptors 7 LFUL017763-PA;LFUL008845-PA;LFUL000646-PA;LFUL016095-PA;LFUL000645-PA;LFUL000647-PA;LFUL010285-PA KEGG: 00630+1.11.1.6 Glyoxylate and dicarboxylate metabolism 2 LFUL005869-PA;LFUL019446-PA Reactome: R-HSA-1474244 Extracellular matrix organization 2 LFUL019569-PA;LFUL009021-PA Reactome: R-HSA-2644606 Constitutive Signaling by NOTCH1 PEST Domain Mutants 30 LFUL003040-PA;LFUL005551-PA;LFUL017466-PA;LFUL003906-PA;LFUL015321-PA;LFUL009003-PA;LFUL008073-PA;LFUL015886-PA;LFUL015476-PA;LFUL016295-PA;LFUL000671-PA;LFUL005973-PA;LFUL017465-PA;LFUL001835-PA;LFUL000121-PA;LFUL008074-PA;LFUL003223-PA;LFUL000672-PA;LFUL004537-PA;LFUL008785-PA;LFUL017467-PA;LFUL019751-PA;LFUL012088-PA;LFUL009679-PA;LFUL017464-PA;LFUL001836-PA;LFUL009829-PA;LFUL004221-PA;LFUL018390-PA;LFUL016227-PA Reactome: R-HSA-427975 Proton/oligopeptide cotransporters 4 LFUL011506-PA;LFUL012140-PA;LFUL009195-PA;LFUL011505-PA Reactome: R-HSA-9013508 NOTCH3 Intracellular Domain Regulates Transcription 6 LFUL001835-PA;LFUL016227-PA;LFUL005551-PA;LFUL001836-PA;LFUL008073-PA;LFUL008074-PA Reactome: R-HSA-3371568 Attenuation phase 4 LFUL008074-PA;LFUL008073-PA;LFUL014299-PA;LFUL014303-PA MetaCyc: PWY-5080 Very long chain fatty acid biosynthesis I 18 LFUL013814-PA;LFUL010698-PA;LFUL012359-PA;LFUL015420-PA;LFUL013815-PA;LFUL006533-PA;LFUL012361-PA;LFUL002423-PA;LFUL013817-PA;LFUL013816-PA;LFUL007078-PA;LFUL015422-PA;LFUL013818-PA;LFUL004766-PA;LFUL012360-PA;LFUL001272-PA;LFUL017948-PA;LFUL001095-PA Reactome: R-HSA-111447 Activation of BAD and translocation to mitochondria 3 LFUL013893-PA;LFUL013894-PA;LFUL015328-PA Reactome: R-HSA-196757 Metabolism of folate and pterines 8 LFUL001565-PA;LFUL019090-PA;LFUL003915-PA;LFUL014192-PA;LFUL004544-PA;LFUL008282-PA;LFUL009609-PA;LFUL015994-PA Reactome: R-HSA-3322077 Glycogen synthesis 5 LFUL005603-PA;LFUL008565-PA;LFUL004537-PA;LFUL014477-PA;LFUL014478-PA MetaCyc: PWY-7524 Mevalonate pathway III (archaea) 2 LFUL007555-PA;LFUL008593-PA MetaCyc: PWY-6344 L-ornithine degradation II (Stickland reaction) 1 LFUL014392-PA KEGG: 00561+3.1.1.23 Glycerolipid metabolism 1 LFUL011856-PA KEGG: 00620+4.2.1.2 Pyruvate metabolism 2 LFUL017636-PA;LFUL017635-PA KEGG: 00620+1.1.1.37 Pyruvate metabolism 3 LFUL004113-PA;LFUL015809-PA;LFUL004114-PA Reactome: R-HSA-8948700 Competing endogenous RNAs (ceRNAs) regulate PTEN translation 8 LFUL005454-PA;LFUL006660-PA;LFUL019805-PA;LFUL006745-PA;LFUL004232-PA;LFUL015532-PA;LFUL019785-PA;LFUL015531-PA Reactome: R-HSA-1483115 Hydrolysis of LPC 8 LFUL008301-PA;LFUL008302-PA;LFUL013371-PA;LFUL002457-PA;LFUL008296-PA;LFUL013370-PA;LFUL008299-PA;LFUL008298-PA MetaCyc: PWY-7035 (9Z)-tricosene biosynthesis 18 LFUL013814-PA;LFUL010698-PA;LFUL012359-PA;LFUL015420-PA;LFUL013815-PA;LFUL006533-PA;LFUL012361-PA;LFUL002423-PA;LFUL013817-PA;LFUL013816-PA;LFUL007078-PA;LFUL004766-PA;LFUL015422-PA;LFUL013818-PA;LFUL012360-PA;LFUL001272-PA;LFUL017948-PA;LFUL001095-PA MetaCyc: PWY-5067 Glycogen biosynthesis II (from UDP-D-Glucose) 4 LFUL007973-PA;LFUL014477-PA;LFUL014478-PA;LFUL005603-PA KEGG: 00062+4.2.1.134 Fatty acid elongation 2 LFUL001272-PA;LFUL010698-PA KEGG: 00900+2.1.1.100 Terpenoid backbone biosynthesis 1 LFUL007591-PA KEGG: 00520+2.7.7.9 Amino sugar and nucleotide sugar metabolism 1 LFUL008565-PA Reactome: R-HSA-5607764 CLEC7A (Dectin-1) signaling 47 LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL014805-PA;LFUL005608-PA;LFUL010280-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA;LFUL015886-PA;LFUL017243-PA;LFUL000924-PA;LFUL015255-PA;LFUL007901-PA;LFUL004537-PA;LFUL001667-PA;LFUL013396-PA;LFUL005657-PA;LFUL018125-PA;LFUL000664-PA;LFUL016970-PA;LFUL003567-PA;LFUL016470-PA;LFUL003914-PA;LFUL009759-PA;LFUL018127-PA;LFUL013254-PA;LFUL006784-PA;LFUL005128-PA;LFUL005189-PA;LFUL015825-PA;LFUL017408-PA;LFUL019638-PA KEGG: 00710+3.1.3.11 Carbon fixation in photosynthetic organisms 2 LFUL000566-PA;LFUL000567-PA Reactome: R-HSA-373080 Class B/2 (Secretin family receptors) 23 LFUL014904-PA;LFUL005535-PA;LFUL006782-PA;LFUL018894-PA;LFUL006465-PA;LFUL005667-PA;LFUL013601-PA;LFUL008807-PA;LFUL016392-PA;LFUL006466-PA;LFUL008806-PA;LFUL006781-PA;LFUL005059-PA;LFUL013600-PA;LFUL014552-PA;LFUL008714-PA;LFUL009527-PA;LFUL004541-PA;LFUL005058-PA;LFUL018069-PA;LFUL004540-PA;LFUL004539-PA;LFUL005666-PA Reactome: R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 5 LFUL010398-PA;LFUL019090-PA;LFUL013047-PA;LFUL004602-PA;LFUL019539-PA KEGG: 00511+3.2.1.45 Other glycan degradation 1 LFUL008313-PA Reactome: R-HSA-75153 Apoptotic execution phase 1 LFUL017497-PA MetaCyc: PWY-6703 Preq0 biosynthesis 2 LFUL019539-PA;LFUL004602-PA Reactome: R-HSA-3656237 Defective EXT2 causes exostoses 2 7 LFUL009642-PA;LFUL003069-PA;LFUL005814-PA;LFUL003070-PA;LFUL002623-PA;LFUL003068-PA;LFUL002624-PA Reactome: R-HSA-75109 Triglyceride biosynthesis 3 LFUL000328-PA;LFUL011019-PA;LFUL011020-PA Reactome: R-HSA-8877330 RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) 4 LFUL009516-PA;LFUL009514-PA;LFUL009515-PA;LFUL009513-PA MetaCyc: PWY-5108 L-isoleucine biosynthesis V 2 LFUL001222-PA;LFUL006868-PA Reactome: R-HSA-2161541 Abacavir metabolism 1 LFUL006399-PA MetaCyc: PWY-5844 Menaquinol-9 biosynthesis 2 LFUL006594-PA;LFUL006592-PA Reactome: R-HSA-174414 Processive synthesis on the C-strand of the telomere 3 LFUL007960-PA;LFUL005720-PA;LFUL006665-PA Reactome: R-HSA-73772 RNA Polymerase I Promoter Escape 26 LFUL006416-PA;LFUL013037-PA;LFUL003284-PA;LFUL001784-PA;LFUL010060-PA;LFUL014212-PA;LFUL015513-PA;LFUL010364-PA;LFUL006931-PA;LFUL004554-PA;LFUL003875-PA;LFUL011954-PA;LFUL003393-PA;LFUL013636-PA;LFUL010467-PA;LFUL010456-PA;LFUL000106-PA;LFUL009752-PA;LFUL002481-PA;LFUL001373-PA;LFUL011953-PA;LFUL001785-PA;LFUL000180-PA;LFUL006932-PA;LFUL010468-PA;LFUL010061-PA Reactome: R-HSA-373753 Nephrin family interactions 1 LFUL008763-PA Reactome: R-HSA-9633012 Response of EIF2AK4 (GCN2) to amino acid deficiency 82 LFUL019054-PA;LFUL014893-PA;LFUL011278-PA;LFUL001681-PA;LFUL017656-PA;LFUL002208-PA;LFUL018953-PA;LFUL001102-PA;LFUL008016-PA;LFUL003947-PA;LFUL012271-PA;LFUL004974-PA;LFUL006720-PA;LFUL009630-PA;LFUL002211-PA;LFUL007358-PA;LFUL017793-PA;LFUL012702-PA;LFUL007583-PA;LFUL006181-PA;LFUL008661-PA;LFUL015696-PA;LFUL002925-PA;LFUL014304-PA;LFUL018772-PA;LFUL007452-PA;LFUL004596-PA;LFUL008669-PA;LFUL017447-PA;LFUL010862-PA;LFUL005634-PA;LFUL014225-PA;LFUL006093-PA;LFUL005206-PA;LFUL002249-PA;LFUL014007-PA;LFUL006675-PA;LFUL011123-PA;LFUL019701-PA;LFUL006255-PA;LFUL019500-PA;LFUL009485-PA;LFUL018450-PA;LFUL003221-PA;LFUL006688-PA;LFUL001717-PA;LFUL000695-PA;LFUL013851-PA;LFUL017436-PA;LFUL005635-PA;LFUL000050-PA;LFUL005935-PA;LFUL004418-PA;LFUL011000-PA;LFUL010852-PA;LFUL002673-PA;LFUL003261-PA;LFUL004537-PA;LFUL001329-PA;LFUL015920-PA;LFUL003757-PA;LFUL016069-PA;LFUL002950-PA;LFUL008294-PA;LFUL004636-PA;LFUL004420-PA;LFUL001176-PA;LFUL006788-PA;LFUL004637-PA;LFUL008330-PA;LFUL006902-PA;LFUL011563-PA;LFUL016060-PA;LFUL009487-PA;LFUL018996-PA;LFUL010275-PA;LFUL015591-PA;LFUL010697-PA;LFUL005171-PA;LFUL016059-PA;LFUL012372-PA;LFUL012852-PA Reactome: R-HSA-2160456 Phenylketonuria 1 LFUL004045-PA KEGG: 00010+5.3.1.9 Glycolysis / Gluconeogenesis 1 LFUL001099-PA KEGG: 00480+2.5.1.16 Glutathione metabolism 2 LFUL016360-PA;LFUL005994-PA MetaCyc: PWY-5981 CDP-diacylglycerol biosynthesis III 9 LFUL002099-PA;LFUL017634-PA;LFUL016131-PA;LFUL016130-PA;LFUL007247-PA;LFUL016045-PA;LFUL008878-PA;LFUL013010-PA;LFUL009878-PA KEGG: 00630+4.2.1.3 Glyoxylate and dicarboxylate metabolism 2 LFUL013084-PA;LFUL012627-PA KEGG: 00750+2.7.1.35 Vitamin B6 metabolism 2 LFUL009425-PA;LFUL006014-PA MetaCyc: PWY-7219 Adenosine ribonucleotides de novo biosynthesis 13 LFUL006106-PA;LFUL000226-PA;LFUL001229-PA;LFUL005983-PA;LFUL003006-PA;LFUL009370-PA;LFUL005981-PA;LFUL008697-PA;LFUL017381-PA;LFUL017382-PA;LFUL012071-PA;LFUL000260-PA;LFUL019525-PA MetaCyc: PWY-6728 Methylaspartate cycle 14 LFUL008263-PA;LFUL015809-PA;LFUL004113-PA;LFUL004029-PA;LFUL017635-PA;LFUL004114-PA;LFUL001123-PA;LFUL012684-PA;LFUL017636-PA;LFUL006558-PA;LFUL006146-PA;LFUL016366-PA;LFUL005914-PA;LFUL006472-PA KEGG: 00680+4.1.2.13 Methane metabolism 1 LFUL011512-PA Reactome: R-HSA-3000471 Scavenging by Class B Receptors 5 LFUL013535-PA;LFUL019397-PA;LFUL018059-PA;LFUL018058-PA;LFUL005945-PA KEGG: 00510+2.4.1.142 N-Glycan biosynthesis 1 LFUL007469-PA MetaCyc: PWY-735 Jasmonic acid biosynthesis 2 LFUL001447-PA;LFUL001448-PA Reactome: R-HSA-69017 CDK-mediated phosphorylation and removal of Cdc6 52 LFUL000664-PA;LFUL016970-PA;LFUL006691-PA;LFUL003567-PA;LFUL011394-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL005657-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL001285-PA;LFUL005128-PA;LFUL008983-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL003914-PA;LFUL006381-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL015871-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL010327-PA;LFUL011827-PA;LFUL017608-PA;LFUL018065-PA;LFUL010331-PA;LFUL001183-PA;LFUL013520-PA;LFUL004085-PA;LFUL011826-PA;LFUL002279-PA;LFUL001413-PA;LFUL001632-PA;LFUL014805-PA;LFUL005608-PA;LFUL000448-PA;LFUL013953-PA MetaCyc: PWY-6607 Guanosine nucleotides degradation I 2 LFUL011206-PA;LFUL011207-PA KEGG: 00680+1.1.1.37 Methane metabolism 3 LFUL004114-PA;LFUL015809-PA;LFUL004113-PA Reactome: R-HSA-426486 Small interfering RNA (siRNA) biogenesis 7 LFUL006660-PA;LFUL004968-PA;LFUL004524-PA;LFUL019785-PA;LFUL000655-PA;LFUL019805-PA;LFUL014268-PA MetaCyc: PWY-7344 UDP-alpha-D-galactose biosynthesis 1 LFUL006901-PA Reactome: R-HSA-8854050 FBXL7 down-regulates AURKA during mitotic entry and in early mitosis 41 LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL009758-PA;LFUL004900-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL014805-PA;LFUL005608-PA;LFUL013520-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL010331-PA;LFUL001183-PA;LFUL001632-PA;LFUL015886-PA;LFUL001413-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL005657-PA;LFUL013396-PA;LFUL017243-PA;LFUL000664-PA;LFUL016970-PA;LFUL003567-PA;LFUL003914-PA;LFUL013254-PA;LFUL006784-PA;LFUL009759-PA;LFUL005128-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA Reactome: R-HSA-5654700 FRS-mediated FGFR2 signaling 1 LFUL006796-PA Reactome: R-HSA-5626467 RHO GTPases activate IQGAPs 17 LFUL014799-PA;LFUL004646-PA;LFUL010682-PA;LFUL013557-PA;LFUL012256-PA;LFUL013560-PA;LFUL010020-PA;LFUL014801-PA;LFUL013555-PA;LFUL010681-PA;LFUL014793-PA;LFUL005324-PA;LFUL013561-PA;LFUL003377-PA;LFUL014800-PA;LFUL014795-PA;LFUL002553-PA KEGG: 00950+2.6.1.1 Isoquinoline alkaloid biosynthesis 2 LFUL003406-PA;LFUL011379-PA Reactome: R-HSA-9022699 MECP2 regulates neuronal receptors and channels 1 LFUL008336-PA Reactome: R-HSA-77288 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids 1 LFUL017943-PA KEGG: 00240+1.17.4.1 Pyrimidine metabolism 19 LFUL001680-PA;LFUL017179-PA;LFUL013124-PA;LFUL019301-PA;LFUL008100-PA;LFUL013859-PA;LFUL004087-PA;LFUL004400-PA;LFUL018976-PA;LFUL016612-PA;LFUL014063-PA;LFUL019252-PA;LFUL014941-PA;LFUL008033-PA;LFUL015842-PA;LFUL005848-PA;LFUL006960-PA;LFUL003861-PA;LFUL019261-PA MetaCyc: PWY-7783 Plasmalogen degradation 20 LFUL016033-PA;LFUL010843-PA;LFUL013307-PA;LFUL013311-PA;LFUL013308-PA;LFUL004585-PA;LFUL012016-PA;LFUL013309-PA;LFUL019491-PA;LFUL016031-PA;LFUL012592-PA;LFUL016032-PA;LFUL002721-PA;LFUL016881-PA;LFUL011621-PA;LFUL002722-PA;LFUL013310-PA;LFUL002720-PA;LFUL016035-PA;LFUL016034-PA MetaCyc: PWY-7841 Neolacto-series glycosphingolipids biosynthesis 1 LFUL014857-PA Reactome: R-HSA-113418 Formation of the Early Elongation Complex 29 LFUL006932-PA;LFUL010468-PA;LFUL016326-PA;LFUL001373-PA;LFUL000564-PA;LFUL010467-PA;LFUL010456-PA;LFUL003393-PA;LFUL008550-PA;LFUL013636-PA;LFUL008827-PA;LFUL004554-PA;LFUL016324-PA;LFUL006931-PA;LFUL000398-PA;LFUL007672-PA;LFUL010620-PA;LFUL003284-PA;LFUL013037-PA;LFUL018856-PA;LFUL015513-PA;LFUL010364-PA;LFUL008825-PA;LFUL000565-PA;LFUL014212-PA;LFUL006416-PA;LFUL014608-PA;LFUL003397-PA;LFUL003797-PA Reactome: R-HSA-446205 Synthesis of GDP-mannose 5 LFUL015612-PA;LFUL000192-PA;LFUL012953-PA;LFUL006343-PA;LFUL006253-PA Reactome: R-HSA-442660 Na+/Cl- dependent neurotransmitter transporters 1 LFUL012388-PA Reactome: R-HSA-73762 RNA Polymerase I Transcription Initiation 29 LFUL009328-PA;LFUL001784-PA;LFUL010060-PA;LFUL013037-PA;LFUL003284-PA;LFUL015513-PA;LFUL010364-PA;LFUL014212-PA;LFUL006416-PA;LFUL002061-PA;LFUL004554-PA;LFUL003875-PA;LFUL001836-PA;LFUL011954-PA;LFUL006931-PA;LFUL010467-PA;LFUL010456-PA;LFUL003393-PA;LFUL013636-PA;LFUL010468-PA;LFUL006932-PA;LFUL001785-PA;LFUL010061-PA;LFUL002481-PA;LFUL000106-PA;LFUL009752-PA;LFUL001835-PA;LFUL011953-PA;LFUL001373-PA Reactome: R-HSA-112311 Neurotransmitter clearance 2 LFUL008159-PA;LFUL006473-PA MetaCyc: PWY-7179 Purine deoxyribonucleosides degradation I 3 LFUL011577-PA;LFUL003389-PA;LFUL011578-PA Reactome: R-HSA-174113 SCF-beta-TrCP mediated degradation of Emi1 41 LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL004537-PA;LFUL005657-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL015255-PA;LFUL017243-PA;LFUL005128-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL003914-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL017218-PA;LFUL017219-PA;LFUL015402-PA;LFUL011816-PA;LFUL009758-PA;LFUL004900-PA;LFUL013520-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL015886-PA;LFUL001632-PA;LFUL001413-PA;LFUL014805-PA;LFUL005608-PA KEGG: 00260+2.3.1.37 Glycine, serine and threonine metabolism 1 LFUL017816-PA Reactome: R-HSA-162594 Early Phase of HIV Life Cycle 1 LFUL009126-PA Reactome: R-HSA-983231 Factors involved in megakaryocyte development and platelet production 43 LFUL018365-PA;LFUL001454-PA;LFUL014411-PA;LFUL001445-PA;LFUL014092-PA;LFUL000669-PA;LFUL018440-PA;LFUL000670-PA;LFUL005324-PA;LFUL016457-PA;LFUL015154-PA;LFUL002491-PA;LFUL004716-PA;LFUL015071-PA;LFUL004714-PA;LFUL014094-PA;LFUL018364-PA;LFUL015967-PA;LFUL014091-PA;LFUL018071-PA;LFUL002711-PA;LFUL014095-PA;LFUL018358-PA;LFUL010375-PA;LFUL002340-PA;LFUL019325-PA;LFUL011442-PA;LFUL019328-PA;LFUL014410-PA;LFUL019326-PA;LFUL002493-PA;LFUL002492-PA;LFUL017127-PA;LFUL015968-PA;LFUL002712-PA;LFUL003807-PA;LFUL007957-PA;LFUL019327-PA;LFUL008336-PA;LFUL017128-PA;LFUL010379-PA;LFUL014408-PA;LFUL002713-PA KEGG: 00260+2.1.2.1 Glycine, serine and threonine metabolism 3 LFUL001565-PA;LFUL009609-PA;LFUL004544-PA KEGG: 00790+1.5.1.3 Folate biosynthesis 1 LFUL019090-PA MetaCyc: PWY-7124 Ethylene biosynthesis V (engineered) 3 LFUL006558-PA;LFUL012684-PA;LFUL011112-PA Reactome: R-HSA-114604 GPVI-mediated activation cascade 3 LFUL005324-PA;LFUL014130-PA;LFUL000924-PA KEGG: 00350+2.6.1.1 Tyrosine metabolism 2 LFUL003406-PA;LFUL011379-PA Reactome: R-HSA-5339716 Misspliced GSK3beta mutants stabilize beta-catenin 4 LFUL010552-PA;LFUL009310-PA;LFUL015628-PA;LFUL007844-PA MetaCyc: PWY-6605 Adenine and adenosine salvage II 1 LFUL004695-PA Reactome: R-HSA-389513 CTLA4 inhibitory signaling 2 LFUL009310-PA;LFUL015628-PA Reactome: R-HSA-1912408 Pre-NOTCH Transcription and Translation 18 LFUL008073-PA;LFUL019785-PA;LFUL014905-PA;LFUL001835-PA;LFUL005551-PA;LFUL019805-PA;LFUL006223-PA;LFUL005454-PA;LFUL006660-PA;LFUL018752-PA;LFUL004232-PA;LFUL001836-PA;LFUL015532-PA;LFUL000101-PA;LFUL015531-PA;LFUL016227-PA;LFUL006745-PA;LFUL008074-PA KEGG: 04658+3.1.3.16 Th1 and Th2 cell differentiation 36 LFUL001158-PA;LFUL004450-PA;LFUL004449-PA;LFUL001499-PA;LFUL001498-PA;LFUL012152-PA;LFUL014700-PA;LFUL004453-PA;LFUL002996-PA;LFUL014533-PA;LFUL005424-PA;LFUL014211-PA;LFUL004454-PA;LFUL004452-PA;LFUL018043-PA;LFUL018101-PA;LFUL018100-PA;LFUL018679-PA;LFUL006251-PA;LFUL017164-PA;LFUL017117-PA;LFUL006643-PA;LFUL019606-PA;LFUL008095-PA;LFUL015075-PA;LFUL010894-PA;LFUL004309-PA;LFUL002610-PA;LFUL014885-PA;LFUL007186-PA;LFUL001904-PA;LFUL011767-PA;LFUL002524-PA;LFUL013098-PA;LFUL013235-PA;LFUL000398-PA MetaCyc: PWY-1361 Benzoyl-coa degradation I (aerobic) 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA Reactome: R-HSA-9013695 NOTCH4 Intracellular Domain Regulates Transcription 6 LFUL008074-PA;LFUL001836-PA;LFUL008073-PA;LFUL005551-PA;LFUL016227-PA;LFUL001835-PA MetaCyc: PWY-7254 TCA cycle VII (acetate-producers) 6 LFUL017635-PA;LFUL008263-PA;LFUL001123-PA;LFUL012684-PA;LFUL017636-PA;LFUL006558-PA Reactome: R-HSA-8949275 RUNX3 Regulates Immune Response and Cell Migration 4 LFUL009513-PA;LFUL009515-PA;LFUL009514-PA;LFUL009516-PA Reactome: R-HSA-5679001 Defective ABCC2 causes Dubin-Johnson syndrome 1 LFUL019455-PA Reactome: R-HSA-70895 Branched-chain amino acid catabolism 7 LFUL004411-PA;LFUL011720-PA;LFUL004412-PA;LFUL009768-PA;LFUL001062-PA;LFUL010267-PA;LFUL014148-PA KEGG: 00514+2.4.1.109 Other types of O-glycan biosynthesis 7 LFUL007240-PA;LFUL002764-PA;LFUL003439-PA;LFUL003052-PA;LFUL003866-PA;LFUL009334-PA;LFUL003867-PA MetaCyc: PWY-4261 Glycerol degradation I 2 LFUL000334-PA;LFUL014953-PA Reactome: R-HSA-2559580 Oxidative Stress Induced Senescence 14 LFUL016716-PA;LFUL014137-PA;LFUL000101-PA;LFUL015532-PA;LFUL015531-PA;LFUL014905-PA;LFUL009466-PA;LFUL010410-PA;LFUL004232-PA;LFUL005454-PA;LFUL007465-PA;LFUL004537-PA;LFUL006745-PA;LFUL004849-PA KEGG: 04070+3.1.4.11 Phosphatidylinositol signaling system 8 LFUL015148-PA;LFUL001462-PA;LFUL014147-PA;LFUL006196-PA;LFUL001109-PA;LFUL006197-PA;LFUL016455-PA;LFUL001461-PA Reactome: R-HSA-2243919 Crosslinking of collagen fibrils 3 LFUL004008-PA;LFUL009021-PA;LFUL019569-PA Reactome: R-HSA-111932 CaMK IV-mediated phosphorylation of CREB 1 LFUL002885-PA Reactome: R-HSA-6803211 TP53 Regulates Transcription of Death Receptors and Ligands 1 LFUL008605-PA MetaCyc: PWY-7533 Gliotoxin biosynthesis 5 LFUL017286-PA;LFUL002357-PA;LFUL000874-PA;LFUL004307-PA;LFUL014136-PA Reactome: R-HSA-1660514 Synthesis of PIPs at the Golgi membrane 5 LFUL004611-PA;LFUL017404-PA;LFUL018428-PA;LFUL002733-PA;LFUL018426-PA Reactome: R-HSA-917937 Iron uptake and transport 4 LFUL015886-PA;LFUL005036-PA;LFUL004537-PA;LFUL012627-PA KEGG: 00330+2.5.1.16 Arginine and proline metabolism 2 LFUL005994-PA;LFUL016360-PA MetaCyc: PWY-6361 1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3) 2 LFUL019642-PA;LFUL014713-PA KEGG: 00340+2.1.2.5 Histidine metabolism 1 LFUL005329-PA KEGG: 00785+2.8.1.8 Lipoic acid metabolism 2 LFUL004145-PA;LFUL004144-PA Reactome: R-HSA-8941332 RUNX2 regulates genes involved in cell migration 4 LFUL009514-PA;LFUL009516-PA;LFUL009513-PA;LFUL009515-PA KEGG: 00230+3.5.4.6 Purine metabolism 1 LFUL000108-PA Reactome: R-HSA-6783984 Glycine degradation 5 LFUL013088-PA;LFUL013283-PA;LFUL013747-PA;LFUL012257-PA;LFUL001198-PA Reactome: R-HSA-445989 TAK1 activates NFkB by phosphorylation and activation of IKKs complex 6 LFUL005189-PA;LFUL018127-PA;LFUL010280-PA;LFUL003145-PA;LFUL018125-PA;LFUL004537-PA Reactome: R-HSA-5675482 Regulation of necroptotic cell death 1 LFUL004537-PA MetaCyc: PWY-8041 Ultra-long-chain fatty acid biosynthesis 18 LFUL015420-PA;LFUL013815-PA;LFUL013814-PA;LFUL010698-PA;LFUL012359-PA;LFUL012361-PA;LFUL002423-PA;LFUL006533-PA;LFUL004766-PA;LFUL013818-PA;LFUL015422-PA;LFUL012360-PA;LFUL013817-PA;LFUL007078-PA;LFUL013816-PA;LFUL017948-PA;LFUL001095-PA;LFUL001272-PA KEGG: 00020+1.1.1.42 Citrate cycle (TCA cycle) 2 LFUL012684-PA;LFUL006558-PA KEGG: 00513+3.2.1.52 Various types of N-glycan biosynthesis 11 LFUL010431-PA;LFUL003459-PA;LFUL001685-PA;LFUL003458-PA;LFUL006590-PA;LFUL007928-PA;LFUL003457-PA;LFUL003417-PA;LFUL006704-PA;LFUL003460-PA;LFUL015340-PA KEGG: 00240+3.6.1.17 Pyrimidine metabolism 1 LFUL000236-PA Reactome: R-HSA-204005 COPII-mediated vesicle transport 25 LFUL013881-PA;LFUL011149-PA;LFUL005822-PA;LFUL000368-PA;LFUL016727-PA;LFUL008001-PA;LFUL001626-PA;LFUL017724-PA;LFUL005094-PA;LFUL004096-PA;LFUL018914-PA;LFUL017990-PA;LFUL001925-PA;LFUL002080-PA;LFUL001003-PA;LFUL010622-PA;LFUL004109-PA;LFUL006151-PA;LFUL003515-PA;LFUL000429-PA;LFUL012613-PA;LFUL014707-PA;LFUL010623-PA;LFUL003767-PA;LFUL003514-PA Reactome: R-HSA-1989781 PPARA activates gene expression 46 LFUL001421-PA;LFUL006181-PA;LFUL006789-PA;LFUL010110-PA;LFUL018610-PA;LFUL008073-PA;LFUL011232-PA;LFUL005476-PA;LFUL000453-PA;LFUL015321-PA;LFUL008921-PA;LFUL008015-PA;LFUL015835-PA;LFUL001690-PA;LFUL009339-PA;LFUL008509-PA;LFUL009817-PA;LFUL000701-PA;LFUL015112-PA;LFUL013284-PA;LFUL018952-PA;LFUL003007-PA;LFUL004728-PA;LFUL001175-PA;LFUL006641-PA;LFUL004729-PA;LFUL000702-PA;LFUL007555-PA;LFUL002649-PA;LFUL009542-PA;LFUL006689-PA;LFUL000811-PA;LFUL001163-PA;LFUL006081-PA;LFUL018367-PA;LFUL003721-PA;LFUL002120-PA;LFUL013458-PA;LFUL018284-PA;LFUL008563-PA;LFUL011231-PA;LFUL009777-PA;LFUL003829-PA;LFUL005014-PA;LFUL013287-PA;LFUL008074-PA Reactome: R-HSA-209560 NF-kB is activated and signals survival 2 LFUL004537-PA;LFUL012905-PA KEGG: 00030+1.1.1.44 Pentose phosphate pathway 1 LFUL013845-PA MetaCyc: PWY-6682 Dehydrophos biosynthesis 1 LFUL003189-PA KEGG: 00230+6.3.3.1 Purine metabolism 1 LFUL013568-PA KEGG: 00710+5.3.1.6 Carbon fixation in photosynthetic organisms 1 LFUL005639-PA KEGG: 00670+1.5.1.3 One carbon pool by folate 1 LFUL019090-PA Reactome: R-HSA-199220 Vitamin B5 (pantothenate) metabolism 2 LFUL006083-PA;LFUL005724-PA Reactome: R-HSA-392517 Rap1 signalling 1 LFUL007947-PA Reactome: R-HSA-5358752 T41 mutants of beta-catenin aren't phosphorylated 4 LFUL015628-PA;LFUL007844-PA;LFUL010552-PA;LFUL009310-PA Reactome: R-HSA-5696400 Dual Incision in GG-NER 29 LFUL011672-PA;LFUL014212-PA;LFUL015513-PA;LFUL005720-PA;LFUL004537-PA;LFUL007960-PA;LFUL003903-PA;LFUL001437-PA;LFUL011164-PA;LFUL004554-PA;LFUL004061-PA;LFUL011668-PA;LFUL005736-PA;LFUL008596-PA;LFUL007277-PA;LFUL019536-PA;LFUL006135-PA;LFUL009325-PA;LFUL013636-PA;LFUL002760-PA;LFUL009780-PA;LFUL007279-PA;LFUL014494-PA;LFUL003393-PA;LFUL000317-PA;LFUL006665-PA;LFUL013345-PA;LFUL011669-PA;LFUL008688-PA KEGG: 00860+4.2.1.24 Porphyrin and chlorophyll metabolism 1 LFUL007835-PA Reactome: R-HSA-8874211 CREB3 factors activate genes 2 LFUL002083-PA;LFUL013958-PA Reactome: R-HSA-392851 Prostacyclin signalling through prostacyclin receptor 5 LFUL012255-PA;LFUL000620-PA;LFUL000640-PA;LFUL003893-PA;LFUL017104-PA Reactome: R-HSA-6798163 Choline catabolism 23 LFUL002605-PA;LFUL001796-PA;LFUL009605-PA;LFUL002584-PA;LFUL002607-PA;LFUL002608-PA;LFUL009604-PA;LFUL015812-PA;LFUL002604-PA;LFUL002609-PA;LFUL008143-PA;LFUL002602-PA;LFUL002598-PA;LFUL002603-PA;LFUL001795-PA;LFUL002600-PA;LFUL000721-PA;LFUL002601-PA;LFUL019710-PA;LFUL008144-PA;LFUL002599-PA;LFUL011661-PA;LFUL002606-PA Reactome: R-HSA-5689896 Ovarian tumor domain proteases 7 LFUL017649-PA;LFUL004013-PA;LFUL005006-PA;LFUL007844-PA;LFUL014224-PA;LFUL004537-PA;LFUL000800-PA MetaCyc: PWY-6611 Adenine and adenosine salvage V 3 LFUL011577-PA;LFUL003389-PA;LFUL011578-PA Reactome: R-HSA-171007 p38MAPK events 1 LFUL009466-PA Reactome: R-HSA-1268020 Mitochondrial protein import 35 LFUL013445-PA;LFUL017637-PA;LFUL013846-PA;LFUL016478-PA;LFUL016356-PA;LFUL001647-PA;LFUL017691-PA;LFUL017908-PA;LFUL007612-PA;LFUL010579-PA;LFUL014937-PA;LFUL003057-PA;LFUL007210-PA;LFUL006424-PA;LFUL007842-PA;LFUL015235-PA;LFUL006133-PA;LFUL008777-PA;LFUL013084-PA;LFUL002088-PA;LFUL013847-PA;LFUL002198-PA;LFUL000665-PA;LFUL017828-PA;LFUL001100-PA;LFUL009677-PA;LFUL015870-PA;LFUL014557-PA;LFUL004016-PA;LFUL007681-PA;LFUL017286-PA;LFUL016787-PA;LFUL017907-PA;LFUL010700-PA;LFUL015872-PA MetaCyc: PWY-7892 Trna-uridine 2-thiolation and selenation (bacteria) 1 LFUL001536-PA MetaCyc: PWY-5331 Taurine biosynthesis I 2 LFUL001559-PA;LFUL001560-PA KEGG: 04070+3.1.3.36 Phosphatidylinositol signaling system 2 LFUL008204-PA;LFUL008439-PA Reactome: R-HSA-8934903 Receptor Mediated Mitophagy 3 LFUL001182-PA;LFUL015758-PA;LFUL007162-PA Reactome: R-HSA-912526 Interleukin receptor SHC signaling 1 LFUL014130-PA Reactome: R-HSA-426496 Post-transcriptional silencing by small RNAs 4 LFUL006660-PA;LFUL005454-PA;LFUL019785-PA;LFUL019805-PA Reactome: R-HSA-156842 Eukaryotic Translation Elongation 4 LFUL009489-PA;LFUL011937-PA;LFUL008759-PA;LFUL017528-PA KEGG: 00500+2.4.1.25 Starch and sucrose metabolism 1 LFUL003990-PA KEGG: 00030+2.2.1.2 Pentose phosphate pathway 1 LFUL002759-PA KEGG: 00670+1.5.1.20 One carbon pool by folate 1 LFUL015994-PA KEGG: 00790+1.14.16.1 Folate biosynthesis 1 LFUL004045-PA Reactome: R-HSA-2428928 IRS-related events triggered by IGF1R 1 LFUL018592-PA Reactome: R-HSA-418555 G alpha (s) signalling events 12 LFUL000620-PA;LFUL004880-PA;LFUL008742-PA;LFUL003893-PA;LFUL010531-PA;LFUL017104-PA;LFUL008741-PA;LFUL014754-PA;LFUL012255-PA;LFUL000754-PA;LFUL000640-PA;LFUL018069-PA Reactome: R-HSA-1855231 Synthesis of IPs in the ER lumen 2 LFUL000389-PA;LFUL003202-PA Reactome: R-HSA-6811434 COPI-dependent Golgi-to-ER retrograde traffic 71 LFUL003377-PA;LFUL000616-PA;LFUL000570-PA;LFUL007845-PA;LFUL014793-PA;LFUL011743-PA;LFUL008594-PA;LFUL013555-PA;LFUL007049-PA;LFUL002129-PA;LFUL007592-PA;LFUL013560-PA;LFUL012613-PA;LFUL007047-PA;LFUL000230-PA;LFUL001925-PA;LFUL000696-PA;LFUL000435-PA;LFUL013045-PA;LFUL014210-PA;LFUL001625-PA;LFUL009164-PA;LFUL005850-PA;LFUL010020-PA;LFUL014801-PA;LFUL003722-PA;LFUL012318-PA;LFUL000076-PA;LFUL014799-PA;LFUL019746-PA;LFUL001638-PA;LFUL007048-PA;LFUL009670-PA;LFUL004639-PA;LFUL014800-PA;LFUL008449-PA;LFUL014915-PA;LFUL017615-PA;LFUL014912-PA;LFUL012286-PA;LFUL007367-PA;LFUL010400-PA;LFUL005086-PA;LFUL010401-PA;LFUL004646-PA;LFUL010682-PA;LFUL000569-PA;LFUL011528-PA;LFUL005811-PA;LFUL005915-PA;LFUL013561-PA;LFUL007390-PA;LFUL008322-PA;LFUL005812-PA;LFUL014795-PA;LFUL003659-PA;LFUL010681-PA;LFUL005851-PA;LFUL019594-PA;LFUL000215-PA;LFUL018877-PA;LFUL012319-PA;LFUL012256-PA;LFUL002040-PA;LFUL003767-PA;LFUL003507-PA;LFUL004949-PA;LFUL013557-PA;LFUL014209-PA;LFUL003661-PA;LFUL005085-PA Reactome: R-HSA-376172 DSCAM interactions 2 LFUL011496-PA;LFUL006810-PA MetaCyc: PWY-6282 Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) 1 LFUL006083-PA Reactome: R-HSA-167238 Pausing and recovery of Tat-mediated HIV elongation 24 LFUL008827-PA;LFUL004885-PA;LFUL008550-PA;LFUL008343-PA;LFUL001373-PA;LFUL016326-PA;LFUL002536-PA;LFUL001415-PA;LFUL006932-PA;LFUL003797-PA;LFUL003397-PA;LFUL014608-PA;LFUL008825-PA;LFUL010364-PA;LFUL010620-PA;LFUL003284-PA;LFUL013037-PA;LFUL018856-PA;LFUL007672-PA;LFUL000398-PA;LFUL002212-PA;LFUL006931-PA;LFUL008342-PA;LFUL016324-PA Reactome: R-HSA-3134973 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production 2 LFUL008074-PA;LFUL008073-PA MetaCyc: PWY-7733 3-hydroxyquinaldate biosynthesis 1 LFUL015273-PA Reactome: R-HSA-2214320 Anchoring fibril formation 2 LFUL009021-PA;LFUL019569-PA Reactome: R-HSA-9665250 Resistance of ERBB2 KD mutants to AEE788 1 LFUL010369-PA Reactome: R-HSA-5632968 Defective Mismatch Repair Associated With MSH6 1 LFUL000900-PA MetaCyc: PWY-6834 Spermidine biosynthesis III 1 LFUL011332-PA MetaCyc: PWY-6683 Assimilatory sulfate reduction III 1 LFUL019316-PA Reactome: R-HSA-4570571 Defective RFT1 causes RFT1-CDG (CDG-1n) 1 LFUL006346-PA Reactome: R-HSA-110328 Recognition and association of DNA glycosylase with site containing an affected pyrimidine 5 LFUL017500-PA;LFUL013973-PA;LFUL014324-PA;LFUL016664-PA;LFUL014854-PA KEGG: 00630+1.1.1.37 Glyoxylate and dicarboxylate metabolism 3 LFUL004114-PA;LFUL015809-PA;LFUL004113-PA MetaCyc: PWY-7922 Protein O-mannosylation II (mammals, core M1 and core M2) 8 LFUL002764-PA;LFUL007240-PA;LFUL003867-PA;LFUL009334-PA;LFUL003866-PA;LFUL003439-PA;LFUL003052-PA;LFUL005787-PA MetaCyc: PWY-882 L-ascorbate biosynthesis I (L-galactose pathway) 2 LFUL000192-PA;LFUL006253-PA KEGG: 00330+1.14.11.2 Arginine and proline metabolism 1 LFUL012323-PA KEGG: 00564+2.7.8.5 Glycerophospholipid metabolism 1 LFUL001902-PA MetaCyc: PWY-6620 Guanine and guanosine salvage 2 LFUL011578-PA;LFUL011577-PA MetaCyc: PWY-7510 Rhizocticin A and B biosynthesis 1 LFUL003189-PA KEGG: 00785+2.3.1.181 Lipoic acid metabolism 3 LFUL003022-PA;LFUL008960-PA;LFUL002318-PA Reactome: R-HSA-9665233 Resistance of ERBB2 KD mutants to trastuzumab 1 LFUL010369-PA Reactome: R-HSA-6811440 Retrograde transport at the Trans-Golgi-Network 33 LFUL012653-PA;LFUL003472-PA;LFUL014963-PA;LFUL018560-PA;LFUL008800-PA;LFUL017747-PA;LFUL008404-PA;LFUL010892-PA;LFUL009177-PA;LFUL000842-PA;LFUL014962-PA;LFUL003767-PA;LFUL005788-PA;LFUL017267-PA;LFUL017228-PA;LFUL015998-PA;LFUL014961-PA;LFUL017881-PA;LFUL011727-PA;LFUL008799-PA;LFUL014959-PA;LFUL009371-PA;LFUL013628-PA;LFUL017882-PA;LFUL011728-PA;LFUL012613-PA;LFUL001812-PA;LFUL018558-PA;LFUL018561-PA;LFUL001925-PA;LFUL000528-PA;LFUL012651-PA;LFUL017751-PA KEGG: 00670+2.1.2.10 One carbon pool by folate 4 LFUL000003-PA;LFUL017290-PA;LFUL012257-PA;LFUL004012-PA Reactome: R-HSA-6804757 Regulation of TP53 Degradation 12 LFUL005288-PA;LFUL004537-PA;LFUL010339-PA;LFUL006140-PA;LFUL000924-PA;LFUL001475-PA;LFUL001476-PA;LFUL007170-PA;LFUL019533-PA;LFUL008562-PA;LFUL006936-PA;LFUL016450-PA Reactome: R-HSA-5686938 Regulation of TLR by endogenous ligand 5 LFUL018059-PA;LFUL005945-PA;LFUL018058-PA;LFUL019397-PA;LFUL013535-PA Reactome: R-HSA-1482925 Acyl chain remodelling of PG 7 LFUL013311-PA;LFUL016881-PA;LFUL013308-PA;LFUL004585-PA;LFUL011621-PA;LFUL012016-PA;LFUL013309-PA KEGG: 00790+6.3.2.17 Folate biosynthesis 1 LFUL008282-PA Reactome: R-HSA-9636467 Blockage of phagosome acidification 3 LFUL011205-PA;LFUL011203-PA;LFUL011204-PA KEGG: 00620+1.1.1.27 Pyruvate metabolism 1 LFUL015394-PA MetaCyc: PWY-6277 Superpathway of 5-aminoimidazole ribonucleotide biosynthesis 3 LFUL017016-PA;LFUL013568-PA;LFUL013571-PA KEGG: 00510+2.4.1.141 N-Glycan biosynthesis 1 LFUL009636-PA Reactome: R-HSA-6807505 RNA polymerase II transcribes snRNA genes 61 LFUL000035-PA;LFUL013957-PA;LFUL008342-PA;LFUL016324-PA;LFUL002017-PA;LFUL015284-PA;LFUL013519-PA;LFUL015525-PA;LFUL012358-PA;LFUL000292-PA;LFUL000291-PA;LFUL010620-PA;LFUL018856-PA;LFUL003924-PA;LFUL011994-PA;LFUL001377-PA;LFUL008825-PA;LFUL015295-PA;LFUL005318-PA;LFUL003925-PA;LFUL008343-PA;LFUL001373-PA;LFUL001935-PA;LFUL012152-PA;LFUL008827-PA;LFUL000564-PA;LFUL003281-PA;LFUL001837-PA;LFUL010346-PA;LFUL019448-PA;LFUL001934-PA;LFUL006931-PA;LFUL017938-PA;LFUL011767-PA;LFUL019512-PA;LFUL017944-PA;LFUL000433-PA;LFUL006416-PA;LFUL014608-PA;LFUL011565-PA;LFUL009113-PA;LFUL001933-PA;LFUL019447-PA;LFUL004050-PA;LFUL003284-PA;LFUL013037-PA;LFUL009867-PA;LFUL010364-PA;LFUL000565-PA;LFUL000617-PA;LFUL002583-PA;LFUL009866-PA;LFUL016326-PA;LFUL015330-PA;LFUL008904-PA;LFUL015283-PA;LFUL006932-PA;LFUL008550-PA;LFUL013956-PA;LFUL001376-PA;LFUL018609-PA KEGG: 00531+3.2.1.50 Glycosaminoglycan degradation 1 LFUL018950-PA MetaCyc: PWY-7802 N-end rule pathway II (prokaryotic) 2 LFUL007629-PA;LFUL013955-PA KEGG: 00565+2.5.1.26 Ether lipid metabolism 4 LFUL018155-PA;LFUL015964-PA;LFUL015965-PA;LFUL018152-PA KEGG: 00040+5.3.1.5 Pentose and glucuronate interconversions 1 LFUL014343-PA Reactome: R-HSA-350562 Regulation of ornithine decarboxylase (ODC) 39 LFUL003914-PA;LFUL013254-PA;LFUL006784-PA;LFUL009759-PA;LFUL005128-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL015255-PA;LFUL007901-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL017243-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL014805-PA;LFUL005608-PA;LFUL013520-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL001183-PA;LFUL010331-PA;LFUL001632-PA;LFUL001413-PA;LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL009758-PA;LFUL004900-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA Reactome: R-HSA-1650814 Collagen biosynthesis and modifying enzymes 6 LFUL012323-PA;LFUL008274-PA;LFUL019569-PA;LFUL009021-PA;LFUL013341-PA;LFUL000176-PA Reactome: R-HSA-391908 Prostanoid ligand receptors 2 LFUL016591-PA;LFUL016592-PA Reactome: R-HSA-72187 mRNA 3'-end processing 35 LFUL017089-PA;LFUL003765-PA;LFUL014785-PA;LFUL002514-PA;LFUL011758-PA;LFUL005950-PA;LFUL004759-PA;LFUL016786-PA;LFUL011279-PA;LFUL017085-PA;LFUL000564-PA;LFUL001010-PA;LFUL005901-PA;LFUL015919-PA;LFUL006595-PA;LFUL004758-PA;LFUL004782-PA;LFUL001187-PA;LFUL005875-PA;LFUL017090-PA;LFUL011823-PA;LFUL001011-PA;LFUL016879-PA;LFUL000565-PA;LFUL002148-PA;LFUL014935-PA;LFUL018008-PA;LFUL016230-PA;LFUL002379-PA;LFUL017088-PA;LFUL005874-PA;LFUL003763-PA;LFUL009571-PA;LFUL005876-PA;LFUL001669-PA Reactome: R-HSA-975871 MyD88 cascade initiated on plasma membrane 2 LFUL013496-PA;LFUL018800-PA Reactome: R-HSA-264642 Acetylcholine Neurotransmitter Release Cycle 2 LFUL010868-PA;LFUL010866-PA Reactome: R-HSA-8852276 The role of GTSE1 in G2/M progression after G2 checkpoint 55 LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL013560-PA;LFUL005128-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL004646-PA;LFUL010682-PA;LFUL003914-PA;LFUL003567-PA;LFUL014800-PA;LFUL016970-PA;LFUL000664-PA;LFUL003377-PA;LFUL017243-PA;LFUL014793-PA;LFUL015255-PA;LFUL013555-PA;LFUL005657-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL001413-PA;LFUL001632-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL010331-PA;LFUL001183-PA;LFUL013520-PA;LFUL012256-PA;LFUL005608-PA;LFUL014805-PA;LFUL013557-PA;LFUL014799-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL014795-PA;LFUL013277-PA;LFUL007684-PA;LFUL013561-PA;LFUL009774-PA;LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL010681-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL010020-PA;LFUL014801-PA KEGG: 00561+2.3.1.15 Glycerolipid metabolism 2 LFUL014100-PA;LFUL016603-PA Reactome: R-HSA-446193 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein 13 LFUL004439-PA;LFUL017161-PA;LFUL013830-PA;LFUL019759-PA;LFUL002634-PA;LFUL015953-PA;LFUL006200-PA;LFUL011924-PA;LFUL013826-PA;LFUL008581-PA;LFUL008663-PA;LFUL009636-PA;LFUL006346-PA Reactome: R-HSA-9603505 NTRK3 as a dependence receptor 1 LFUL007672-PA Reactome: R-HSA-749476 RNA Polymerase III Abortive And Retractive Initiation 32 LFUL011294-PA;LFUL001093-PA;LFUL014294-PA;LFUL003911-PA;LFUL002583-PA;LFUL010063-PA;LFUL014846-PA;LFUL006932-PA;LFUL010061-PA;LFUL009113-PA;LFUL011565-PA;LFUL011471-PA;LFUL010762-PA;LFUL013037-PA;LFUL003284-PA;LFUL010060-PA;LFUL010364-PA;LFUL005061-PA;LFUL006931-PA;LFUL006422-PA;LFUL017259-PA;LFUL010148-PA;LFUL000388-PA;LFUL002481-PA;LFUL015295-PA;LFUL001373-PA;LFUL010149-PA;LFUL012358-PA;LFUL015504-PA;LFUL015757-PA;LFUL003390-PA;LFUL000035-PA KEGG: 00270+4.2.1.109 Cysteine and methionine metabolism 1 LFUL001636-PA KEGG: 00860+4.4.1.17 Porphyrin and chlorophyll metabolism 1 LFUL016708-PA KEGG: 00270+2.5.1.6 Cysteine and methionine metabolism 1 LFUL012283-PA KEGG: 00790+4.1.99.22 Folate biosynthesis 2 LFUL004972-PA;LFUL004970-PA Reactome: R-HSA-392154 Nitric oxide stimulates guanylate cyclase 4 LFUL016952-PA;LFUL015110-PA;LFUL001456-PA;LFUL003623-PA MetaCyc: PWY-7198 Pyrimidine deoxyribonucleotides de novo biosynthesis IV 30 LFUL019261-PA;LFUL017852-PA;LFUL005983-PA;LFUL017739-PA;LFUL006960-PA;LFUL003861-PA;LFUL005848-PA;LFUL015842-PA;LFUL011295-PA;LFUL008033-PA;LFUL014941-PA;LFUL019252-PA;LFUL014063-PA;LFUL002259-PA;LFUL005425-PA;LFUL016612-PA;LFUL013982-PA;LFUL004400-PA;LFUL018976-PA;LFUL008636-PA;LFUL004087-PA;LFUL002258-PA;LFUL013859-PA;LFUL005981-PA;LFUL003582-PA;LFUL008100-PA;LFUL019301-PA;LFUL013124-PA;LFUL017179-PA;LFUL001680-PA KEGG: 00640+4.1.1.9 Propanoate metabolism 1 LFUL013004-PA Reactome: R-HSA-169911 Regulation of Apoptosis 2 LFUL012452-PA;LFUL012450-PA Reactome: R-HSA-2559586 DNA Damage/Telomere Stress Induced Senescence 5 LFUL001126-PA;LFUL006936-PA;LFUL014004-PA;LFUL004631-PA;LFUL004632-PA Reactome: R-HSA-9009391 Extra-nuclear estrogen signaling 6 LFUL014130-PA;LFUL000620-PA;LFUL012255-PA;LFUL000640-PA;LFUL017104-PA;LFUL003893-PA Reactome: R-HSA-445144 Signal transduction by L1 2 LFUL014137-PA;LFUL007162-PA KEGG: 00600+3.2.1.22 Sphingolipid metabolism 2 LFUL015844-PA;LFUL015843-PA Reactome: R-HSA-4720454 Defective ALG9 causes ALG9-CDG (CDG-1l) 1 LFUL004439-PA KEGG: 00534+2.4.1.224+2.4.1.225 Glycosaminoglycan biosynthesis - heparan sulfate / heparin 3 LFUL003069-PA;LFUL003070-PA;LFUL003068-PA KEGG: 00720+1.3.5.1 Carbon fixation pathways in prokaryotes 2 LFUL008263-PA;LFUL001123-PA Reactome: R-HSA-5368286 Mitochondrial translation initiation 66 LFUL001850-PA;LFUL011692-PA;LFUL007667-PA;LFUL005481-PA;LFUL007422-PA;LFUL014313-PA;LFUL002976-PA;LFUL009337-PA;LFUL005053-PA;LFUL003376-PA;LFUL002738-PA;LFUL003473-PA;LFUL010873-PA;LFUL001323-PA;LFUL004614-PA;LFUL001460-PA;LFUL008019-PA;LFUL007295-PA;LFUL000609-PA;LFUL004130-PA;LFUL001663-PA;LFUL001538-PA;LFUL017525-PA;LFUL000378-PA;LFUL019763-PA;LFUL003929-PA;LFUL001176-PA;LFUL004509-PA;LFUL006854-PA;LFUL007900-PA;LFUL014875-PA;LFUL000320-PA;LFUL007542-PA;LFUL004150-PA;LFUL011340-PA;LFUL007369-PA;LFUL012013-PA;LFUL017678-PA;LFUL005922-PA;LFUL013892-PA;LFUL005723-PA;LFUL006429-PA;LFUL000080-PA;LFUL015276-PA;LFUL007191-PA;LFUL010234-PA;LFUL008017-PA;LFUL014003-PA;LFUL015537-PA;LFUL012340-PA;LFUL008064-PA;LFUL001184-PA;LFUL007188-PA;LFUL017732-PA;LFUL004956-PA;LFUL017828-PA;LFUL003101-PA;LFUL009315-PA;LFUL015233-PA;LFUL002078-PA;LFUL000344-PA;LFUL007193-PA;LFUL004190-PA;LFUL009757-PA;LFUL014538-PA;LFUL010173-PA MetaCyc: PWY-7511 Protein ubiquitination 110 LFUL004075-PA;LFUL014721-PA;LFUL007598-PA;LFUL017168-PA;LFUL009041-PA;LFUL000227-PA;LFUL009797-PA;LFUL015428-PA;LFUL012335-PA;LFUL011297-PA;LFUL004078-PA;LFUL009796-PA;LFUL015191-PA;LFUL012144-PA;LFUL008200-PA;LFUL011298-PA;LFUL012096-PA;LFUL015405-PA;LFUL013409-PA;LFUL017221-PA;LFUL002919-PA;LFUL003758-PA;LFUL008618-PA;LFUL003046-PA;LFUL006508-PA;LFUL018871-PA;LFUL009675-PA;LFUL001396-PA;LFUL004074-PA;LFUL017892-PA;LFUL012889-PA;LFUL009236-PA;LFUL003842-PA;LFUL018149-PA;LFUL015292-PA;LFUL014936-PA;LFUL011341-PA;LFUL015189-PA;LFUL007983-PA;LFUL005953-PA;LFUL004156-PA;LFUL008619-PA;LFUL000079-PA;LFUL012888-PA;LFUL015406-PA;LFUL011535-PA;LFUL014255-PA;LFUL014693-PA;LFUL019616-PA;LFUL008199-PA;LFUL013331-PA;LFUL014254-PA;LFUL009702-PA;LFUL000078-PA;LFUL015407-PA;LFUL007458-PA;LFUL018148-PA;LFUL001867-PA;LFUL008231-PA;LFUL004210-PA;LFUL007813-PA;LFUL000319-PA;LFUL013171-PA;LFUL013020-PA;LFUL002435-PA;LFUL002044-PA;LFUL010036-PA;LFUL018300-PA;LFUL010585-PA;LFUL012656-PA;LFUL002382-PA;LFUL002045-PA;LFUL002344-PA;LFUL011948-PA;LFUL001205-PA;LFUL011128-PA;LFUL005453-PA;LFUL009423-PA;LFUL000671-PA;LFUL017224-PA;LFUL012527-PA;LFUL001406-PA;LFUL011122-PA;LFUL006397-PA;LFUL011127-PA;LFUL009040-PA;LFUL013363-PA;LFUL018299-PA;LFUL019676-PA;LFUL009894-PA;LFUL007969-PA;LFUL018453-PA;LFUL000672-PA;LFUL015392-PA;LFUL012890-PA;LFUL004212-PA;LFUL005891-PA;LFUL001361-PA;LFUL006020-PA;LFUL015391-PA;LFUL004005-PA;LFUL014403-PA;LFUL010014-PA;LFUL018621-PA;LFUL012657-PA;LFUL018454-PA;LFUL008230-PA;LFUL001360-PA;LFUL013244-PA;LFUL010229-PA Reactome: R-HSA-9037629 Lewis blood group biosynthesis 1 LFUL004984-PA Reactome: R-HSA-198323 AKT phosphorylates targets in the cytosol 6 LFUL006443-PA;LFUL010552-PA;LFUL004784-PA;LFUL004580-PA;LFUL004581-PA;LFUL010551-PA KEGG: 00564+3.1.1.32 Glycerophospholipid metabolism 1 LFUL015933-PA MetaCyc: PWY-7709 (3R)-linalool biosynthesis 2 LFUL011744-PA;LFUL004955-PA KEGG: 00052+3.5.1.25 Galactose metabolism 1 LFUL003224-PA Reactome: R-HSA-71240 Tryptophan catabolism 9 LFUL013723-PA;LFUL008867-PA;LFUL008866-PA;LFUL013724-PA;LFUL015273-PA;LFUL016193-PA;LFUL003571-PA;LFUL019496-PA;LFUL016192-PA Reactome: R-HSA-2032785 YAP1- and WWTR1 (TAZ)-stimulated gene expression 4 LFUL015462-PA;LFUL015464-PA;LFUL000001-PA;LFUL015463-PA KEGG: 00520+5.3.1.8 Amino sugar and nucleotide sugar metabolism 1 LFUL006253-PA KEGG: 00790+4.6.1.17 Folate biosynthesis 1 LFUL004970-PA Reactome: R-HSA-6784531 tRNA processing in the nucleus 44 LFUL000581-PA;LFUL000200-PA;LFUL012019-PA;LFUL005157-PA;LFUL006358-PA;LFUL014144-PA;LFUL011549-PA;LFUL011763-PA;LFUL016880-PA;LFUL002532-PA;LFUL008437-PA;LFUL008320-PA;LFUL016186-PA;LFUL001451-PA;LFUL009031-PA;LFUL019553-PA;LFUL001010-PA;LFUL007602-PA;LFUL005156-PA;LFUL017097-PA;LFUL015687-PA;LFUL018131-PA;LFUL009840-PA;LFUL013801-PA;LFUL008319-PA;LFUL010864-PA;LFUL009511-PA;LFUL005565-PA;LFUL013881-PA;LFUL009305-PA;LFUL011215-PA;LFUL009303-PA;LFUL001011-PA;LFUL002533-PA;LFUL008059-PA;LFUL010903-PA;LFUL002487-PA;LFUL008321-PA;LFUL016205-PA;LFUL002666-PA;LFUL005951-PA;LFUL008185-PA;LFUL015477-PA;LFUL006282-PA KEGG: 00010+2.7.1.1 Glycolysis / Gluconeogenesis 3 LFUL004281-PA;LFUL004280-PA;LFUL003646-PA Reactome: R-HSA-2142700 Synthesis of Lipoxins (LX) 2 LFUL000104-PA;LFUL000084-PA Reactome: R-HSA-200425 Carnitine metabolism 3 LFUL005590-PA;LFUL006242-PA;LFUL005606-PA Reactome: R-HSA-430039 mRNA decay by 5' to 3' exoribonuclease 14 LFUL006626-PA;LFUL001404-PA;LFUL005320-PA;LFUL014178-PA;LFUL000541-PA;LFUL004062-PA;LFUL006763-PA;LFUL008384-PA;LFUL006625-PA;LFUL018232-PA;LFUL013450-PA;LFUL017484-PA;LFUL014469-PA;LFUL003877-PA Reactome: R-HSA-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle 12 LFUL008556-PA;LFUL017984-PA;LFUL003913-PA;LFUL012875-PA;LFUL006498-PA;LFUL003914-PA;LFUL004537-PA;LFUL014908-PA;LFUL017221-PA;LFUL013521-PA;LFUL014909-PA;LFUL005006-PA KEGG: 00680+4.2.1.11 Methane metabolism 1 LFUL011112-PA MetaCyc: PWY-621 Sucrose degradation III (sucrose invertase) 1 LFUL001099-PA KEGG: 00520+5.4.2.10 Amino sugar and nucleotide sugar metabolism 4 LFUL012196-PA;LFUL012198-PA;LFUL002430-PA;LFUL002432-PA KEGG: 00270+1.13.11.54 Cysteine and methionine metabolism 1 LFUL005625-PA Reactome: R-HSA-5218920 VEGFR2 mediated vascular permeability 11 LFUL018250-PA;LFUL010339-PA;LFUL000924-PA;LFUL018097-PA;LFUL006140-PA;LFUL005288-PA;LFUL006181-PA;LFUL001476-PA;LFUL001475-PA;LFUL019533-PA;LFUL007170-PA Reactome: R-HSA-9013507 NOTCH3 Activation and Transmission of Signal to the Nucleus 11 LFUL003906-PA;LFUL008785-PA;LFUL004537-PA;LFUL000121-PA;LFUL000672-PA;LFUL018390-PA;LFUL004221-PA;LFUL005973-PA;LFUL000671-PA;LFUL009679-PA;LFUL019751-PA MetaCyc: PWY-7746 Mycobacterial sulfolipid biosynthesis 1 LFUL006083-PA Reactome: R-HSA-70921 Histidine catabolism 4 LFUL004916-PA;LFUL005502-PA;LFUL010993-PA;LFUL005329-PA KEGG: 00640+4.2.1.17 Propanoate metabolism 3 LFUL018646-PA;LFUL017943-PA;LFUL012393-PA KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41 Biotin metabolism 1 LFUL006083-PA Reactome: R-HSA-418890 Role of second messengers in netrin-1 signaling 7 LFUL013481-PA;LFUL018616-PA;LFUL005124-PA;LFUL010050-PA;LFUL013480-PA;LFUL005154-PA;LFUL005045-PA KEGG: 00510+2.7.1.108 N-Glycan biosynthesis 1 LFUL006417-PA KEGG: 00563+2.4.1.198 Glycosylphosphatidylinositol (GPI)-anchor biosynthesis 3 LFUL018014-PA;LFUL000582-PA;LFUL000610-PA Reactome: R-HSA-8854214 TBC/RABGAPs 8 LFUL008214-PA;LFUL002364-PA;LFUL004581-PA;LFUL004580-PA;LFUL016215-PA;LFUL007749-PA;LFUL012151-PA;LFUL007750-PA KEGG: 00480+2.5.1.18 Glutathione metabolism 2 LFUL014136-PA;LFUL004307-PA Reactome: R-HSA-71403 Citric acid cycle (TCA cycle) 20 LFUL005097-PA;LFUL010112-PA;LFUL013846-PA;LFUL004515-PA;LFUL017635-PA;LFUL001123-PA;LFUL012684-PA;LFUL017636-PA;LFUL006558-PA;LFUL006472-PA;LFUL013847-PA;LFUL008263-PA;LFUL006557-PA;LFUL013084-PA;LFUL015809-PA;LFUL004029-PA;LFUL002772-PA;LFUL016366-PA;LFUL005914-PA;LFUL001874-PA Reactome: R-HSA-9029569 NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux 9 LFUL015532-PA;LFUL019785-PA;LFUL015531-PA;LFUL004232-PA;LFUL006745-PA;LFUL019805-PA;LFUL006660-PA;LFUL009777-PA;LFUL005454-PA Reactome: R-HSA-9634285 Constitutive Signaling by Overexpressed ERBB2 1 LFUL010369-PA Reactome: R-HSA-111471 Apoptotic factor-mediated response 1 LFUL010237-PA Reactome: R-HSA-428543 Inactivation of CDC42 and RAC1 1 LFUL005324-PA Reactome: R-HSA-1912420 Pre-NOTCH Processing in Golgi 3 LFUL006223-PA;LFUL009789-PA;LFUL018752-PA Reactome: R-HSA-9637628 Modulation by Mtb of host immune system 1 LFUL004537-PA Reactome: R-HSA-156582 Acetylation 1 LFUL000219-PA Reactome: R-HSA-3214841 PKMTs methylate histone lysines 21 LFUL015879-PA;LFUL019672-PA;LFUL000348-PA;LFUL016716-PA;LFUL004906-PA;LFUL013113-PA;LFUL015175-PA;LFUL002871-PA;LFUL010270-PA;LFUL004849-PA;LFUL016378-PA;LFUL011069-PA;LFUL000349-PA;LFUL012073-PA;LFUL012798-PA;LFUL001592-PA;LFUL012693-PA;LFUL010269-PA;LFUL007465-PA;LFUL005001-PA;LFUL002872-PA Reactome: R-HSA-199418 Negative regulation of the PI3K/AKT network 1 LFUL006181-PA MetaCyc: PWY-5695 Inosine 5'-phosphate degradation 4 LFUL011207-PA;LFUL011577-PA;LFUL011206-PA;LFUL011578-PA KEGG: 00073+1.2.1.84 Cutin, suberine and wax biosynthesis 18 LFUL013655-PA;LFUL013656-PA;LFUL010157-PA;LFUL013658-PA;LFUL008789-PA;LFUL012819-PA;LFUL018767-PA;LFUL013657-PA;LFUL012816-PA;LFUL018766-PA;LFUL012818-PA;LFUL012811-PA;LFUL012813-PA;LFUL012814-PA;LFUL012820-PA;LFUL002995-PA;LFUL012817-PA;LFUL010158-PA MetaCyc: PWY-4361 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I 6 LFUL001636-PA;LFUL005625-PA;LFUL019224-PA;LFUL018466-PA;LFUL010188-PA;LFUL003374-PA Reactome: R-HSA-8951664 Neddylation 111 LFUL007734-PA;LFUL012369-PA;LFUL015448-PA;LFUL004537-PA;LFUL007901-PA;LFUL015255-PA;LFUL007799-PA;LFUL002866-PA;LFUL015128-PA;LFUL015756-PA;LFUL011164-PA;LFUL003567-PA;LFUL008596-PA;LFUL000664-PA;LFUL006691-PA;LFUL002212-PA;LFUL001478-PA;LFUL006784-PA;LFUL004595-PA;LFUL011081-PA;LFUL009295-PA;LFUL002488-PA;LFUL016470-PA;LFUL003914-PA;LFUL000150-PA;LFUL004885-PA;LFUL001016-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL004900-PA;LFUL014616-PA;LFUL015402-PA;LFUL002710-PA;LFUL017218-PA;LFUL004061-PA;LFUL006668-PA;LFUL018603-PA;LFUL009122-PA;LFUL003630-PA;LFUL009774-PA;LFUL000683-PA;LFUL011111-PA;LFUL005463-PA;LFUL014156-PA;LFUL011322-PA;LFUL009596-PA;LFUL006876-PA;LFUL015886-PA;LFUL012606-PA;LFUL001632-PA;LFUL010331-PA;LFUL018065-PA;LFUL001890-PA;LFUL000305-PA;LFUL013520-PA;LFUL015346-PA;LFUL005659-PA;LFUL017243-PA;LFUL008483-PA;LFUL013396-PA;LFUL001667-PA;LFUL005657-PA;LFUL011069-PA;LFUL009872-PA;LFUL016970-PA;LFUL013707-PA;LFUL008484-PA;LFUL009759-PA;LFUL002495-PA;LFUL013254-PA;LFUL003524-PA;LFUL002635-PA;LFUL011082-PA;LFUL005128-PA;LFUL009598-PA;LFUL002975-PA;LFUL009758-PA;LFUL014615-PA;LFUL011816-PA;LFUL019465-PA;LFUL017219-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL002973-PA;LFUL010207-PA;LFUL013277-PA;LFUL016951-PA;LFUL003941-PA;LFUL007684-PA;LFUL001798-PA;LFUL008981-PA;LFUL007705-PA;LFUL005608-PA;LFUL001480-PA;LFUL012646-PA;LFUL002709-PA;LFUL014805-PA;LFUL002193-PA;LFUL000296-PA;LFUL001013-PA;LFUL001413-PA;LFUL005810-PA;LFUL014512-PA;LFUL001183-PA;LFUL017608-PA;LFUL010327-PA;LFUL002708-PA;LFUL006986-PA;LFUL014403-PA MetaCyc: PWY-6614 Tetrahydrofolate biosynthesis 1 LFUL019090-PA Reactome: R-HSA-5628897 TP53 Regulates Metabolic Genes 49 LFUL002377-PA;LFUL004931-PA;LFUL015993-PA;LFUL004581-PA;LFUL001475-PA;LFUL005454-PA;LFUL004571-PA;LFUL006140-PA;LFUL009573-PA;LFUL002108-PA;LFUL005590-PA;LFUL001099-PA;LFUL001585-PA;LFUL012362-PA;LFUL016180-PA;LFUL013894-PA;LFUL001476-PA;LFUL007046-PA;LFUL006294-PA;LFUL012076-PA;LFUL011021-PA;LFUL003072-PA;LFUL017055-PA;LFUL006745-PA;LFUL002198-PA;LFUL009057-PA;LFUL000772-PA;LFUL012961-PA;LFUL019785-PA;LFUL017369-PA;LFUL006660-PA;LFUL015328-PA;LFUL012151-PA;LFUL008160-PA;LFUL019805-PA;LFUL007423-PA;LFUL006345-PA;LFUL004232-PA;LFUL015532-PA;LFUL015531-PA;LFUL004580-PA;LFUL013893-PA;LFUL017054-PA;LFUL001081-PA;LFUL010339-PA;LFUL001193-PA;LFUL012347-PA;LFUL007825-PA;LFUL004570-PA MetaCyc: PWY-3661-1 Glycine betaine degradation II (mammalian) 3 LFUL009609-PA;LFUL004544-PA;LFUL001565-PA Reactome: R-HSA-8964539 Glutamate and glutamine metabolism 4 LFUL013157-PA;LFUL017915-PA;LFUL012349-PA;LFUL003072-PA Reactome: R-HSA-9634600 Regulation of glycolysis by fructose 2,6-bisphosphate metabolism 2 LFUL010045-PA;LFUL005759-PA Reactome: R-HSA-3108214 SUMOylation of DNA damage response and repair proteins 34 LFUL000581-PA;LFUL000200-PA;LFUL006358-PA;LFUL005157-PA;LFUL011549-PA;LFUL001333-PA;LFUL016880-PA;LFUL002532-PA;LFUL005423-PA;LFUL016186-PA;LFUL002671-PA;LFUL005156-PA;LFUL015687-PA;LFUL018131-PA;LFUL009840-PA;LFUL006602-PA;LFUL013801-PA;LFUL010864-PA;LFUL000929-PA;LFUL005736-PA;LFUL005565-PA;LFUL013881-PA;LFUL009305-PA;LFUL009303-PA;LFUL007832-PA;LFUL000928-PA;LFUL015191-PA;LFUL002533-PA;LFUL008059-PA;LFUL000175-PA;LFUL002666-PA;LFUL014854-PA;LFUL004290-PA;LFUL006282-PA MetaCyc: PWY-6322 Phosphinothricin tripeptide biosynthesis 1 LFUL003189-PA Reactome: R-HSA-212676 Dopamine Neurotransmitter Release Cycle 3 LFUL010866-PA;LFUL010868-PA;LFUL014216-PA MetaCyc: PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis 1 LFUL007957-PA Reactome: R-HSA-6791226 Major pathway of rRNA processing in the nucleolus and cytosol 148 LFUL002940-PA;LFUL011123-PA;LFUL001918-PA;LFUL000768-PA;LFUL015696-PA;LFUL014304-PA;LFUL008668-PA;LFUL010862-PA;LFUL008669-PA;LFUL008611-PA;LFUL015598-PA;LFUL009872-PA;LFUL014741-PA;LFUL003541-PA;LFUL007583-PA;LFUL004687-PA;LFUL019054-PA;LFUL004565-PA;LFUL013342-PA;LFUL008016-PA;LFUL018953-PA;LFUL001681-PA;LFUL017656-PA;LFUL002208-PA;LFUL011278-PA;LFUL014893-PA;LFUL009487-PA;LFUL012852-PA;LFUL009163-PA;LFUL012372-PA;LFUL014323-PA;LFUL005171-PA;LFUL006622-PA;LFUL007907-PA;LFUL004066-PA;LFUL015591-PA;LFUL001176-PA;LFUL004636-PA;LFUL004420-PA;LFUL002127-PA;LFUL007098-PA;LFUL013239-PA;LFUL016069-PA;LFUL006902-PA;LFUL010925-PA;LFUL004637-PA;LFUL009098-PA;LFUL006788-PA;LFUL001616-PA;LFUL014335-PA;LFUL008319-PA;LFUL015691-PA;LFUL006337-PA;LFUL004418-PA;LFUL011333-PA;LFUL006176-PA;LFUL002673-PA;LFUL003261-PA;LFUL003227-PA;LFUL001717-PA;LFUL000695-PA;LFUL008612-PA;LFUL006688-PA;LFUL015236-PA;LFUL003221-PA;LFUL019182-PA;LFUL019500-PA;LFUL009485-PA;LFUL008185-PA;LFUL005935-PA;LFUL013344-PA;LFUL013851-PA;LFUL000677-PA;LFUL003396-PA;LFUL017436-PA;LFUL006093-PA;LFUL014225-PA;LFUL013536-PA;LFUL008320-PA;LFUL006675-PA;LFUL019701-PA;LFUL013238-PA;LFUL014007-PA;LFUL009607-PA;LFUL002249-PA;LFUL009314-PA;LFUL018772-PA;LFUL010371-PA;LFUL002925-PA;LFUL008661-PA;LFUL007908-PA;LFUL004353-PA;LFUL007434-PA;LFUL017447-PA;LFUL007452-PA;LFUL004596-PA;LFUL003662-PA;LFUL017793-PA;LFUL013323-PA;LFUL010404-PA;LFUL007358-PA;LFUL015740-PA;LFUL009630-PA;LFUL012371-PA;LFUL006075-PA;LFUL010888-PA;LFUL012702-PA;LFUL006624-PA;LFUL000595-PA;LFUL005093-PA;LFUL003947-PA;LFUL006720-PA;LFUL004974-PA;LFUL012271-PA;LFUL001102-PA;LFUL003231-PA;LFUL007470-PA;LFUL018996-PA;LFUL016060-PA;LFUL016059-PA;LFUL002939-PA;LFUL010697-PA;LFUL015271-PA;LFUL010275-PA;LFUL001204-PA;LFUL015338-PA;LFUL002950-PA;LFUL015920-PA;LFUL011563-PA;LFUL008330-PA;LFUL013343-PA;LFUL010852-PA;LFUL011000-PA;LFUL012669-PA;LFUL011544-PA;LFUL002448-PA;LFUL018238-PA;LFUL008422-PA;LFUL001329-PA;LFUL004537-PA;LFUL010903-PA;LFUL013449-PA;LFUL008321-PA;LFUL014614-PA;LFUL018450-PA;LFUL006255-PA;LFUL000050-PA;LFUL006413-PA Reactome: R-HSA-72662 Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S 2 LFUL018435-PA;LFUL016269-PA KEGG: 00230+3.5.4.3 Purine metabolism 1 LFUL011735-PA MetaCyc: PWY-8001 Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis 6 LFUL016403-PA;LFUL012058-PA;LFUL012059-PA;LFUL016402-PA;LFUL003732-PA;LFUL015031-PA KEGG: 00130+4.1.1.90 Ubiquinone and other terpenoid-quinone biosynthesis 1 LFUL006033-PA KEGG: 00400+2.6.1.1 Phenylalanine, tyrosine and tryptophan biosynthesis 2 LFUL011379-PA;LFUL003406-PA MetaCyc: PWY-7216 (R)- and (S)-3-hydroxybutanoate biosynthesis (engineered) 3 LFUL012393-PA;LFUL017943-PA;LFUL018646-PA Reactome: R-HSA-8939256 RUNX1 regulates transcription of genes involved in WNT signaling 4 LFUL009514-PA;LFUL009516-PA;LFUL009513-PA;LFUL009515-PA Reactome: R-HSA-1442490 Collagen degradation 8 LFUL000176-PA;LFUL009003-PA;LFUL007858-PA;LFUL015476-PA;LFUL013341-PA;LFUL009021-PA;LFUL008274-PA;LFUL019569-PA Reactome: R-HSA-4719360 Defective DPM3 causes DPM3-CDG (CDG-1o) 2 LFUL005787-PA;LFUL007324-PA MetaCyc: PWY-7909 Formaldehyde oxidation VII (THF pathway) 2 LFUL014192-PA;LFUL003915-PA Reactome: R-HSA-9615710 Late endosomal microautophagy 8 LFUL000787-PA;LFUL012973-PA;LFUL002957-PA;LFUL004537-PA;LFUL002956-PA;LFUL003450-PA;LFUL001539-PA;LFUL010679-PA MetaCyc: PWY-7214 Baicalein degradation (hydrogen peroxide detoxification) 7 LFUL010194-PA;LFUL010193-PA;LFUL010195-PA;LFUL006897-PA;LFUL006904-PA;LFUL004976-PA;LFUL019366-PA KEGG: 00710+2.6.1.1 Carbon fixation in photosynthetic organisms 2 LFUL003406-PA;LFUL011379-PA KEGG: 00130+2.5.1.39 Ubiquinone and other terpenoid-quinone biosynthesis 2 LFUL017907-PA;LFUL017908-PA KEGG: 00513+2.4.1.257+2.4.1.132 Various types of N-glycan biosynthesis 1 LFUL013826-PA KEGG: 00270+1.1.1.37 Cysteine and methionine metabolism 3 LFUL004114-PA;LFUL015809-PA;LFUL004113-PA Reactome: R-HSA-75893 TNF signaling 1 LFUL009003-PA KEGG: 00564+3.1.3.4 Glycerophospholipid metabolism 3 LFUL011019-PA;LFUL005920-PA;LFUL011020-PA MetaCyc: PWY-6907 Thiamine diphosphate biosynthesis III (Staphylococcus) 1 LFUL006365-PA KEGG: 00930+3.1.1.17 Caprolactam degradation 2 LFUL004102-PA;LFUL001189-PA KEGG: 00500+2.7.1.1 Starch and sucrose metabolism 3 LFUL004281-PA;LFUL004280-PA;LFUL003646-PA Reactome: R-HSA-163680 AMPK inhibits chREBP transcriptional activation activity 2 LFUL013749-PA;LFUL005590-PA KEGG: 00760+2.4.2.1 Nicotinate and nicotinamide metabolism 2 LFUL011577-PA;LFUL011578-PA Reactome: R-HSA-9013700 NOTCH4 Activation and Transmission of Signal to the Nucleus 4 LFUL003906-PA;LFUL018390-PA;LFUL008785-PA;LFUL005973-PA MetaCyc: PWY-7851 Coenzyme A biosynthesis II (eukaryotic) 2 LFUL013489-PA;LFUL001707-PA KEGG: 00600+3.2.1.45 Sphingolipid metabolism 1 LFUL008313-PA Reactome: R-HSA-390471 Association of TriC/CCT with target proteins during biosynthesis 17 LFUL009144-PA;LFUL000696-PA;LFUL004595-PA;LFUL010663-PA;LFUL000920-PA;LFUL004185-PA;LFUL007016-PA;LFUL002937-PA;LFUL005926-PA;LFUL017103-PA;LFUL007147-PA;LFUL002975-PA;LFUL005812-PA;LFUL001282-PA;LFUL002973-PA;LFUL001283-PA;LFUL012106-PA MetaCyc: PWY-7391 Isoprene biosynthesis II (engineered) 4 LFUL015364-PA;LFUL008593-PA;LFUL007555-PA;LFUL011043-PA Reactome: R-HSA-8874081 MET activates PTK2 signaling 6 LFUL005332-PA;LFUL010340-PA;LFUL002806-PA;LFUL000176-PA;LFUL002807-PA;LFUL013341-PA Reactome: R-HSA-211945 Phase I - Functionalization of compounds 3 LFUL008257-PA;LFUL013284-PA;LFUL008509-PA KEGG: 00562+3.1.3.64 Inositol phosphate metabolism 1 LFUL012230-PA Reactome: R-HSA-3899300 SUMOylation of transcription cofactors 6 LFUL008336-PA;LFUL008073-PA;LFUL008074-PA;LFUL002401-PA;LFUL016450-PA;LFUL000787-PA KEGG: 00010+4.1.1.32 Glycolysis / Gluconeogenesis 1 LFUL010175-PA Reactome: R-HSA-917977 Transferrin endocytosis and recycling 15 LFUL008406-PA;LFUL009162-PA;LFUL010662-PA;LFUL010191-PA;LFUL006787-PA;LFUL006476-PA;LFUL010201-PA;LFUL009771-PA;LFUL018924-PA;LFUL006212-PA;LFUL008957-PA;LFUL011205-PA;LFUL011203-PA;LFUL003394-PA;LFUL011204-PA KEGG: 00720+6.4.1.3 Carbon fixation pathways in prokaryotes 1 LFUL006146-PA MetaCyc: PWY-3841 Folate transformations II (plants) 9 LFUL015994-PA;LFUL009609-PA;LFUL014192-PA;LFUL002259-PA;LFUL004544-PA;LFUL003915-PA;LFUL001565-PA;LFUL019090-PA;LFUL002258-PA Reactome: R-HSA-1236394 Signaling by ERBB4 1 LFUL018415-PA Reactome: R-HSA-1362277 Transcription of E2F targets under negative control by DREAM complex 7 LFUL009289-PA;LFUL015871-PA;LFUL014016-PA;LFUL006665-PA;LFUL014149-PA;LFUL000101-PA;LFUL013765-PA MetaCyc: PWY-7433 Mucin core 1 and core 2 O-glycosylation 3 LFUL018255-PA;LFUL004586-PA;LFUL019109-PA Reactome: R-HSA-877300 Interferon gamma signaling 4 LFUL016850-PA;LFUL016327-PA;LFUL002885-PA;LFUL003917-PA KEGG: 00620+2.7.1.40 Pyruvate metabolism 1 LFUL001192-PA Reactome: R-HSA-416482 G alpha (12/13) signalling events 22 LFUL014579-PA;LFUL014180-PA;LFUL000640-PA;LFUL003526-PA;LFUL019649-PA;LFUL000248-PA;LFUL005446-PA;LFUL001155-PA;LFUL003893-PA;LFUL017104-PA;LFUL013611-PA;LFUL003790-PA;LFUL001301-PA;LFUL004990-PA;LFUL008198-PA;LFUL012255-PA;LFUL013612-PA;LFUL001466-PA;LFUL003791-PA;LFUL001303-PA;LFUL019644-PA;LFUL000620-PA Reactome: R-HSA-982772 Growth hormone receptor signaling 2 LFUL014137-PA;LFUL009003-PA MetaCyc: PWY-6692 Fe(II) oxidation 1 LFUL009172-PA MetaCyc: PWY-7250 [2Fe-2S] iron-sulfur cluster biosynthesis 2 LFUL008951-PA;LFUL008950-PA MetaCyc: PWY-6470 Peptidoglycan biosynthesis V (beta-lactam resistance) 2 LFUL009636-PA;LFUL006200-PA MetaCyc: PWY-6372 1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium) 3 LFUL014193-PA;LFUL014713-PA;LFUL019642-PA KEGG: 00564+1.1.5.3 Glycerophospholipid metabolism 1 LFUL000334-PA Reactome: R-HSA-2162123 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) 2 LFUL007664-PA;LFUL002455-PA MetaCyc: PWY-5913 Partial TCA cycle (obligate autotrophs) 13 LFUL011379-PA;LFUL004113-PA;LFUL015809-PA;LFUL004029-PA;LFUL017635-PA;LFUL003406-PA;LFUL012684-PA;LFUL004114-PA;LFUL006558-PA;LFUL017636-PA;LFUL006472-PA;LFUL005914-PA;LFUL016366-PA MetaCyc: PWY-7979 Protein O-mannosylation III (mammals, core M3) 9 LFUL007240-PA;LFUL002764-PA;LFUL003866-PA;LFUL003867-PA;LFUL009334-PA;LFUL003439-PA;LFUL017446-PA;LFUL005787-PA;LFUL003052-PA MetaCyc: PWY-7833 Biosynthesis of Lewis epitopes (H. pylori) 4 LFUL008153-PA;LFUL004664-PA;LFUL015209-PA;LFUL014202-PA KEGG: 00670+2.1.2.5 One carbon pool by folate 1 LFUL005329-PA Reactome: R-HSA-1236974 ER-Phagosome pathway 45 LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL003914-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL005128-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL007901-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL005608-PA;LFUL018800-PA;LFUL010280-PA;LFUL014805-PA;LFUL006280-PA;LFUL001413-PA;LFUL001632-PA;LFUL010677-PA;LFUL000923-PA;LFUL010327-PA;LFUL018065-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA Reactome: R-HSA-8939243 RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known 21 LFUL010410-PA;LFUL018622-PA;LFUL009515-PA;LFUL006362-PA;LFUL007162-PA;LFUL010816-PA;LFUL000742-PA;LFUL018025-PA;LFUL009513-PA;LFUL009658-PA;LFUL004988-PA;LFUL018026-PA;LFUL009514-PA;LFUL005566-PA;LFUL005567-PA;LFUL004989-PA;LFUL019711-PA;LFUL000743-PA;LFUL009237-PA;LFUL019463-PA;LFUL009516-PA Reactome: R-HSA-881907 Gastrin-CREB signalling pathway via PKC and MAPK 1 LFUL014137-PA Reactome: R-HSA-5658034 HHAT G278V abrogates palmitoylation of Hh-Np 2 LFUL005058-PA;LFUL005059-PA KEGG: 00760+6.3.4.21 Nicotinate and nicotinamide metabolism 1 LFUL011944-PA Reactome: R-HSA-6804758 Regulation of TP53 Activity through Acetylation 4 LFUL002061-PA;LFUL018073-PA;LFUL018912-PA;LFUL012345-PA Reactome: R-HSA-6803529 FGFR2 alternative splicing 13 LFUL000565-PA;LFUL008825-PA;LFUL010364-PA;LFUL010620-PA;LFUL003284-PA;LFUL018856-PA;LFUL013037-PA;LFUL000564-PA;LFUL008827-PA;LFUL008550-PA;LFUL006932-PA;LFUL001373-PA;LFUL006931-PA MetaCyc: PWY-6580 Phosphatidylinositol biosynthesis I (bacteria) 2 LFUL014193-PA;LFUL012230-PA MetaCyc: PWY-6643 Coenzyme M biosynthesis II 2 LFUL003406-PA;LFUL011379-PA MetaCyc: PWY-7919 Protein N-glycosylation processing phase (plants and animals) 1 LFUL012875-PA KEGG: 00620+3.1.2.6 Pyruvate metabolism 1 LFUL006267-PA KEGG: 00220+1.14.13.39 Arginine biosynthesis 1 LFUL001456-PA Reactome: R-HSA-77305 Beta oxidation of palmitoyl-CoA to myristoyl-CoA 1 LFUL017943-PA MetaCyc: PWY-7206 Pyrimidine deoxyribonucleotides dephosphorylation 2 LFUL000002-PA;LFUL014206-PA Reactome: R-HSA-392170 ADP signalling through P2Y purinoceptor 12 5 LFUL012255-PA;LFUL000620-PA;LFUL000640-PA;LFUL003893-PA;LFUL017104-PA Reactome: R-HSA-182971 EGFR downregulation 4 LFUL013808-PA;LFUL005324-PA;LFUL004537-PA;LFUL005095-PA Reactome: R-HSA-114516 Disinhibition of SNARE formation 1 LFUL007151-PA MetaCyc: PWY-5074 Mevalonate degradation 1 LFUL018576-PA Reactome: R-HSA-72163 mRNA Splicing - Major Pathway 99 LFUL017090-PA;LFUL009274-PA;LFUL001011-PA;LFUL010364-PA;LFUL002148-PA;LFUL012907-PA;LFUL016230-PA;LFUL012078-PA;LFUL008550-PA;LFUL018323-PA;LFUL011316-PA;LFUL002815-PA;LFUL005578-PA;LFUL000483-PA;LFUL017570-PA;LFUL000117-PA;LFUL014365-PA;LFUL007217-PA;LFUL017089-PA;LFUL012861-PA;LFUL016561-PA;LFUL001377-PA;LFUL011758-PA;LFUL008825-PA;LFUL006763-PA;LFUL006292-PA;LFUL004759-PA;LFUL016786-PA;LFUL019480-PA;LFUL004315-PA;LFUL014111-PA;LFUL011935-PA;LFUL008827-PA;LFUL001105-PA;LFUL000113-PA;LFUL009060-PA;LFUL000564-PA;LFUL001373-PA;LFUL016817-PA;LFUL014553-PA;LFUL001187-PA;LFUL011823-PA;LFUL003758-PA;LFUL000565-PA;LFUL014178-PA;LFUL013037-PA;LFUL003284-PA;LFUL004058-PA;LFUL006004-PA;LFUL016227-PA;LFUL014935-PA;LFUL006931-PA;LFUL009181-PA;LFUL018232-PA;LFUL014469-PA;LFUL003879-PA;LFUL018957-PA;LFUL017088-PA;LFUL015674-PA;LFUL001376-PA;LFUL009286-PA;LFUL007582-PA;LFUL013450-PA;LFUL001669-PA;LFUL006932-PA;LFUL016599-PA;LFUL009321-PA;LFUL000041-PA;LFUL014785-PA;LFUL000593-PA;LFUL002514-PA;LFUL017451-PA;LFUL011233-PA;LFUL018856-PA;LFUL005950-PA;LFUL003378-PA;LFUL010620-PA;LFUL006001-PA;LFUL003103-PA;LFUL017230-PA;LFUL002300-PA;LFUL017484-PA;LFUL016290-PA;LFUL011130-PA;LFUL001938-PA;LFUL003877-PA;LFUL018697-PA;LFUL010238-PA;LFUL017085-PA;LFUL001010-PA;LFUL005901-PA;LFUL000796-PA;LFUL015919-PA;LFUL006021-PA;LFUL006595-PA;LFUL004758-PA;LFUL006364-PA;LFUL011498-PA;LFUL001203-PA Reactome: R-HSA-500753 Pyrimidine biosynthesis 5 LFUL003607-PA;LFUL010923-PA;LFUL006717-PA;LFUL014037-PA;LFUL006715-PA KEGG: 00052+2.7.1.6 Galactose metabolism 3 LFUL010336-PA;LFUL010337-PA;LFUL004776-PA Reactome: R-HSA-901032 ER Quality Control Compartment (ERQC) 7 LFUL017168-PA;LFUL006462-PA;LFUL012656-PA;LFUL017221-PA;LFUL006461-PA;LFUL004537-PA;LFUL012657-PA KEGG: 00280+4.2.1.17 Valine, leucine and isoleucine degradation 1 LFUL017943-PA KEGG: 00250+4.3.2.2 Alanine, aspartate and glutamate metabolism 1 LFUL001229-PA Reactome: R-HSA-379726 Mitochondrial tRNA aminoacylation 11 LFUL007798-PA;LFUL003447-PA;LFUL013267-PA;LFUL007703-PA;LFUL015626-PA;LFUL011768-PA;LFUL013240-PA;LFUL015053-PA;LFUL012296-PA;LFUL014891-PA;LFUL005459-PA Reactome: R-HSA-164378 PKA activation in glucagon signalling 7 LFUL014754-PA;LFUL008741-PA;LFUL015154-PA;LFUL008742-PA;LFUL004880-PA;LFUL000754-PA;LFUL010531-PA Reactome: R-HSA-8941284 RUNX2 regulates chondrocyte maturation 4 LFUL009514-PA;LFUL009516-PA;LFUL009513-PA;LFUL009515-PA Reactome: R-HSA-9649948 Signaling downstream of RAS mutants 6 LFUL015596-PA;LFUL015597-PA;LFUL014137-PA;LFUL002885-PA;LFUL011508-PA;LFUL001132-PA Reactome: R-HSA-1257604 PIP3 activates AKT signaling 11 LFUL014130-PA;LFUL006181-PA;LFUL019533-PA;LFUL007170-PA;LFUL001476-PA;LFUL001475-PA;LFUL000924-PA;LFUL006140-PA;LFUL010339-PA;LFUL018800-PA;LFUL005288-PA Reactome: R-HSA-174490 Membrane binding and targetting of GAG proteins 7 LFUL004537-PA;LFUL002956-PA;LFUL003450-PA;LFUL012973-PA;LFUL002957-PA;LFUL001539-PA;LFUL010679-PA Reactome: R-HSA-5603029 IkBA variant leads to EDA-ID 1 LFUL010280-PA KEGG: 00627+3.6.1.7 Aminobenzoate degradation 1 LFUL009013-PA KEGG: 00510+2.7.8.15 N-Glycan biosynthesis 1 LFUL006200-PA Reactome: R-HSA-8963693 Aspartate and asparagine metabolism 6 LFUL002779-PA;LFUL002777-PA;LFUL002780-PA;LFUL019683-PA;LFUL005206-PA;LFUL002778-PA Reactome: R-HSA-69052 Switching of origins to a post-replicative state 8 LFUL006063-PA;LFUL004865-PA;LFUL012130-PA;LFUL007704-PA;LFUL009340-PA;LFUL019733-PA;LFUL012288-PA;LFUL004598-PA Reactome: R-HSA-168927 TICAM1, RIP1-mediated IKK complex recruitment 2 LFUL010280-PA;LFUL004537-PA KEGG: 00970+6.1.1.2 Aminoacyl-tRNA biosynthesis 2 LFUL012296-PA;LFUL003583-PA KEGG: 00521+5.5.1.4 Streptomycin biosynthesis 1 LFUL014193-PA Reactome: R-HSA-176407 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase 11 LFUL006381-PA;LFUL000448-PA;LFUL013953-PA;LFUL011827-PA;LFUL001285-PA;LFUL006691-PA;LFUL008983-PA;LFUL004085-PA;LFUL002279-PA;LFUL011826-PA;LFUL011394-PA Reactome: R-HSA-5683826 Surfactant metabolism 2 LFUL003389-PA;LFUL003252-PA MetaCyc: PWY-5873 Ubiquinol-7 biosynthesis (eukaryotic) 4 LFUL002067-PA;LFUL017907-PA;LFUL000814-PA;LFUL017908-PA Reactome: R-HSA-187577 SCF(Skp2)-mediated degradation of p27/p21 40 LFUL017218-PA;LFUL017219-PA;LFUL015402-PA;LFUL011816-PA;LFUL009758-PA;LFUL004900-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL014805-PA;LFUL005608-PA;LFUL013520-PA;LFUL010331-PA;LFUL001183-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL015886-PA;LFUL001632-PA;LFUL001413-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL005657-PA;LFUL015255-PA;LFUL017243-PA;LFUL016970-PA;LFUL000664-PA;LFUL003914-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL005128-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA MetaCyc: PWY-6938 NADH repair 2 LFUL001404-PA;LFUL001910-PA MetaCyc: PWY-7822 Chitin degradation III (Serratia) 19 LFUL009656-PA;LFUL003457-PA;LFUL003501-PA;LFUL009655-PA;LFUL001844-PA;LFUL015340-PA;LFUL013525-PA;LFUL003458-PA;LFUL010431-PA;LFUL010999-PA;LFUL000955-PA;LFUL007928-PA;LFUL003417-PA;LFUL006704-PA;LFUL003460-PA;LFUL003459-PA;LFUL001685-PA;LFUL000956-PA;LFUL006590-PA KEGG: 00730+2.8.1.7 Thiamine metabolism 2 LFUL008950-PA;LFUL008951-PA Reactome: R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs 50 LFUL004069-PA;LFUL005094-PA;LFUL016727-PA;LFUL018219-PA;LFUL014961-PA;LFUL014959-PA;LFUL009442-PA;LFUL007036-PA;LFUL004484-PA;LFUL011881-PA;LFUL011411-PA;LFUL011257-PA;LFUL005802-PA;LFUL002080-PA;LFUL005864-PA;LFUL012948-PA;LFUL001419-PA;LFUL017271-PA;LFUL011413-PA;LFUL010425-PA;LFUL003472-PA;LFUL004096-PA;LFUL014963-PA;LFUL008001-PA;LFUL004283-PA;LFUL004483-PA;LFUL018220-PA;LFUL005863-PA;LFUL005867-PA;LFUL006470-PA;LFUL006735-PA;LFUL002250-PA;LFUL004031-PA;LFUL001287-PA;LFUL014114-PA;LFUL001314-PA;LFUL005866-PA;LFUL015733-PA;LFUL015734-PA;LFUL011371-PA;LFUL018221-PA;LFUL012976-PA;LFUL014962-PA;LFUL010623-PA;LFUL010622-PA;LFUL006734-PA;LFUL017990-PA;LFUL015534-PA;LFUL010235-PA;LFUL015136-PA Reactome: R-HSA-111465 Apoptotic cleavage of cellular proteins 3 LFUL014815-PA;LFUL007844-PA;LFUL003920-PA Reactome: R-HSA-6782210 Gap-filling DNA repair synthesis and ligation in TC-NER 46 LFUL008550-PA;LFUL007279-PA;LFUL009325-PA;LFUL010467-PA;LFUL007277-PA;LFUL019536-PA;LFUL010456-PA;LFUL008688-PA;LFUL006932-PA;LFUL003758-PA;LFUL006416-PA;LFUL007960-PA;LFUL003903-PA;LFUL004537-PA;LFUL013502-PA;LFUL013037-PA;LFUL003284-PA;LFUL010364-PA;LFUL011672-PA;LFUL014212-PA;LFUL008596-PA;LFUL005736-PA;LFUL006931-PA;LFUL011668-PA;LFUL004554-PA;LFUL011164-PA;LFUL014494-PA;LFUL003393-PA;LFUL000113-PA;LFUL002760-PA;LFUL013636-PA;LFUL011669-PA;LFUL008562-PA;LFUL006986-PA;LFUL013345-PA;LFUL001373-PA;LFUL010468-PA;LFUL006665-PA;LFUL000593-PA;LFUL000117-PA;LFUL014365-PA;LFUL007187-PA;LFUL010620-PA;LFUL015513-PA;LFUL005720-PA;LFUL001437-PA Reactome: R-HSA-210455 Astrocytic Glutamate-Glutamine Uptake And Metabolism 1 LFUL012349-PA Reactome: R-HSA-5619052 Defective SLC9A9 causes autism 16 (AUTS16) 1 LFUL009519-PA KEGG: 00620+6.4.1.2 Pyruvate metabolism 1 LFUL005606-PA KEGG: 00510+2.4.1.256 N-Glycan biosynthesis 2 LFUL019759-PA;LFUL017161-PA Reactome: R-HSA-5668541 TNFR2 non-canonical NF-kB pathway 40 LFUL014805-PA;LFUL005608-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL011817-PA;LFUL003913-PA;LFUL010441-PA;LFUL003914-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL005128-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL017243-PA;LFUL015255-PA;LFUL007901-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL013396-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA Reactome: R-HSA-418990 Adherens junctions interactions 3 LFUL018258-PA;LFUL018097-PA;LFUL018250-PA Reactome: R-HSA-73933 Resolution of Abasic Sites (AP sites) 1 LFUL008002-PA Reactome: R-HSA-139853 Elevation of cytosolic Ca2+ levels 7 LFUL009246-PA;LFUL003556-PA;LFUL007272-PA;LFUL007630-PA;LFUL009249-PA;LFUL001443-PA;LFUL007631-PA Reactome: R-HSA-420499 Class C/3 (Metabotropic glutamate/pheromone receptors) 8 LFUL002841-PA;LFUL013351-PA;LFUL013350-PA;LFUL013353-PA;LFUL018659-PA;LFUL002843-PA;LFUL002845-PA;LFUL013005-PA KEGG: 00627+1.14.14.1 Aminobenzoate degradation 2 LFUL019543-PA;LFUL007894-PA Reactome: R-HSA-419771 Opsins 15 LFUL019770-PA;LFUL019835-PA;LFUL019778-PA;LFUL019832-PA;LFUL019788-PA;LFUL019777-PA;LFUL019833-PA;LFUL019836-PA;LFUL019831-PA;LFUL019786-PA;LFUL019824-PA;LFUL019834-PA;LFUL019776-PA;LFUL019804-PA;LFUL019783-PA Reactome: R-HSA-5676934 Protein repair 4 LFUL018009-PA;LFUL004568-PA;LFUL012363-PA;LFUL016529-PA Reactome: R-HSA-1855204 Synthesis of IP3 and IP4 in the cytosol 11 LFUL008439-PA;LFUL001461-PA;LFUL016455-PA;LFUL006197-PA;LFUL014147-PA;LFUL001109-PA;LFUL006196-PA;LFUL001462-PA;LFUL007957-PA;LFUL008204-PA;LFUL015148-PA Reactome: R-HSA-6804115 TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 14 LFUL001139-PA;LFUL001140-PA;LFUL014924-PA;LFUL014929-PA;LFUL006347-PA;LFUL008408-PA;LFUL002732-PA;LFUL014923-PA;LFUL011516-PA;LFUL000511-PA;LFUL002731-PA;LFUL014926-PA;LFUL014931-PA;LFUL006098-PA MetaCyc: PWY-5941 Glycogen degradation II 2 LFUL003990-PA;LFUL012958-PA Reactome: R-HSA-9029558 NR1H2 & NR1H3 regulate gene expression linked to lipogenesis 2 LFUL005724-PA;LFUL006083-PA KEGG: 00520+3.2.1.14 Amino sugar and nucleotide sugar metabolism 8 LFUL010999-PA;LFUL000956-PA;LFUL009655-PA;LFUL009656-PA;LFUL003501-PA;LFUL000955-PA;LFUL013525-PA;LFUL001844-PA Reactome: R-HSA-918233 TRAF3-dependent IRF activation pathway 3 LFUL008074-PA;LFUL008073-PA;LFUL018695-PA Reactome: R-HSA-5620916 VxPx cargo-targeting to cilium 10 LFUL012655-PA;LFUL014617-PA;LFUL014118-PA;LFUL013117-PA;LFUL003097-PA;LFUL007698-PA;LFUL007699-PA;LFUL013119-PA;LFUL004647-PA;LFUL004648-PA KEGG: 00513+2.4.1.141 Various types of N-glycan biosynthesis 1 LFUL009636-PA MetaCyc: PWY-5749 Itaconate degradation 1 LFUL004029-PA MetaCyc: PWY-5054 D-sorbitol biosynthesis I 1 LFUL001099-PA Reactome: R-HSA-196780 Biotin transport and metabolism 5 LFUL010442-PA;LFUL004188-PA;LFUL005606-PA;LFUL009296-PA;LFUL006146-PA KEGG: 00473+5.1.1.1 D-Alanine metabolism 1 LFUL007185-PA MetaCyc: PWY-8106 Queuosine biosynthesis III (queuosine salvage) 2 LFUL001075-PA;LFUL003796-PA Reactome: R-HSA-383280 Nuclear Receptor transcription pathway 39 LFUL002491-PA;LFUL005585-PA;LFUL016690-PA;LFUL008378-PA;LFUL014620-PA;LFUL001141-PA;LFUL001142-PA;LFUL004716-PA;LFUL005663-PA;LFUL001143-PA;LFUL000303-PA;LFUL000301-PA;LFUL006411-PA;LFUL004233-PA;LFUL005986-PA;LFUL018367-PA;LFUL003471-PA;LFUL004236-PA;LFUL012309-PA;LFUL005584-PA;LFUL006162-PA;LFUL012308-PA;LFUL009970-PA;LFUL004436-PA;LFUL013730-PA;LFUL006409-PA;LFUL002701-PA;LFUL007782-PA;LFUL004234-PA;LFUL005486-PA;LFUL004434-PA;LFUL018412-PA;LFUL002493-PA;LFUL002492-PA;LFUL007780-PA;LFUL015161-PA;LFUL015967-PA;LFUL018175-PA;LFUL017165-PA Reactome: R-HSA-180746 Nuclear import of Rev protein 23 LFUL005156-PA;LFUL006282-PA;LFUL015687-PA;LFUL018131-PA;LFUL009840-PA;LFUL013801-PA;LFUL002666-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL008059-PA;LFUL002533-PA;LFUL016186-PA;LFUL010864-PA;LFUL000581-PA;LFUL012019-PA;LFUL000200-PA;LFUL006358-PA;LFUL005157-PA;LFUL011549-PA;LFUL005565-PA;LFUL016880-PA Reactome: R-HSA-5633231 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) 2 LFUL002634-PA;LFUL009636-PA Reactome: R-HSA-4641258 Degradation of DVL 41 LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL005657-PA;LFUL001667-PA;LFUL013396-PA;LFUL007901-PA;LFUL003567-PA;LFUL000664-PA;LFUL016970-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL003914-PA;LFUL017408-PA;LFUL015825-PA;LFUL016359-PA;LFUL019638-PA;LFUL005128-PA;LFUL004900-PA;LFUL009758-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL017218-PA;LFUL003913-PA;LFUL011817-PA;LFUL010441-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL005608-PA;LFUL014805-PA;LFUL001413-PA;LFUL001632-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL001183-PA;LFUL010331-PA;LFUL013520-PA Reactome: R-HSA-5083627 Defective LARGE causes MDDGA6 and MDDGB6 5 LFUL016229-PA;LFUL014492-PA;LFUL014010-PA;LFUL015026-PA;LFUL015024-PA KEGG: 04070+2.7.1.137 Phosphatidylinositol signaling system 1 LFUL004611-PA Reactome: R-HSA-5083628 Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3 3 LFUL004915-PA;LFUL004914-PA;LFUL016141-PA MetaCyc: PWY-922 Mevalonate pathway I 4 LFUL007555-PA;LFUL008593-PA;LFUL011043-PA;LFUL015364-PA KEGG: 00562+2.7.1.137 Inositol phosphate metabolism 1 LFUL004611-PA Reactome: R-HSA-2691232 Constitutive Signaling by NOTCH1 HD Domain Mutants 9 LFUL000671-PA;LFUL004221-PA;LFUL015476-PA;LFUL009679-PA;LFUL009003-PA;LFUL019751-PA;LFUL004537-PA;LFUL000672-PA;LFUL000121-PA Reactome: R-HSA-5678771 Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1 1 LFUL001421-PA MetaCyc: PWY-5757 Fosfomycin biosynthesis 1 LFUL003189-PA KEGG: 00562+2.7.1.158 Inositol phosphate metabolism 2 LFUL019642-PA;LFUL014713-PA MetaCyc: PWY-7918 Protein N-glycosylation processing phase (yeast) 1 LFUL012875-PA KEGG: 00900+4.1.1.33 Terpenoid backbone biosynthesis 1 LFUL011043-PA Reactome: R-HSA-2871809 FCERI mediated Ca+2 mobilization 3 LFUL009246-PA;LFUL009249-PA;LFUL001462-PA MetaCyc: PWY-5659 GDP-mannose biosynthesis 3 LFUL006253-PA;LFUL001099-PA;LFUL000192-PA Reactome: R-HSA-9022537 Loss of MECP2 binding ability to the NCoR/SMRT complex 1 LFUL009777-PA KEGG: 00970+6.1.1.16 Aminoacyl-tRNA biosynthesis 3 LFUL006446-PA;LFUL010162-PA;LFUL010160-PA KEGG: 00643+1.13.11.5 Styrene degradation 2 LFUL012337-PA;LFUL012336-PA MetaCyc: PWY-7724 Icosapentaenoate biosynthesis III (8-desaturase, mammals) 18 LFUL017948-PA;LFUL001095-PA;LFUL001272-PA;LFUL004766-PA;LFUL015422-PA;LFUL013818-PA;LFUL012360-PA;LFUL013817-PA;LFUL007078-PA;LFUL013816-PA;LFUL012361-PA;LFUL002423-PA;LFUL006533-PA;LFUL015420-PA;LFUL013815-PA;LFUL013814-PA;LFUL010698-PA;LFUL012359-PA Reactome: R-HSA-2022854 Keratan sulfate biosynthesis 10 LFUL015715-PA;LFUL010147-PA;LFUL003233-PA;LFUL015024-PA;LFUL002613-PA;LFUL005593-PA;LFUL016229-PA;LFUL014010-PA;LFUL015026-PA;LFUL014492-PA KEGG: 00633+2.3.1.5 Nitrotoluene degradation 1 LFUL000219-PA Reactome: R-HSA-5689603 UCH proteinases 60 LFUL017243-PA;LFUL005657-PA;LFUL004537-PA;LFUL001667-PA;LFUL007901-PA;LFUL013396-PA;LFUL015255-PA;LFUL004224-PA;LFUL000664-PA;LFUL016970-PA;LFUL015692-PA;LFUL007336-PA;LFUL004222-PA;LFUL016629-PA;LFUL003567-PA;LFUL009763-PA;LFUL012951-PA;LFUL012676-PA;LFUL004223-PA;LFUL011349-PA;LFUL010109-PA;LFUL003914-PA;LFUL009759-PA;LFUL006784-PA;LFUL013254-PA;LFUL002836-PA;LFUL001811-PA;LFUL005128-PA;LFUL019638-PA;LFUL015825-PA;LFUL012677-PA;LFUL017408-PA;LFUL015402-PA;LFUL011816-PA;LFUL015690-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL015317-PA;LFUL009758-PA;LFUL008306-PA;LFUL013277-PA;LFUL009774-PA;LFUL006279-PA;LFUL007684-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL008637-PA;LFUL014805-PA;LFUL005608-PA;LFUL010331-PA;LFUL001183-PA;LFUL017608-PA;LFUL010327-PA;LFUL018065-PA;LFUL007881-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA KEGG: 00720+6.3.4.3 Carbon fixation pathways in prokaryotes 1 LFUL003915-PA MetaCyc: PWY-7494 Choline degradation IV 1 LFUL008143-PA MetaCyc: PWY-3881 Mannitol biosynthesis 1 LFUL006253-PA KEGG: 00561+2.7.7.9 Glycerolipid metabolism 1 LFUL008565-PA Reactome: R-HSA-5250971 Toxicity of botulinum toxin type C (BoNT/C) 2 LFUL012020-PA;LFUL012021-PA Reactome: R-HSA-5362798 Release of Hh-Np from the secreting cell 4 LFUL002086-PA;LFUL005058-PA;LFUL009003-PA;LFUL005059-PA Reactome: R-HSA-75815 Ubiquitin-dependent degradation of Cyclin D 41 LFUL003914-PA;LFUL013254-PA;LFUL006784-PA;LFUL009759-PA;LFUL005128-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL015255-PA;LFUL001667-PA;LFUL004537-PA;LFUL005657-PA;LFUL007901-PA;LFUL013396-PA;LFUL017243-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL014805-PA;LFUL005608-PA;LFUL010552-PA;LFUL013520-PA;LFUL010327-PA;LFUL018065-PA;LFUL017608-PA;LFUL001183-PA;LFUL010331-PA;LFUL001632-PA;LFUL001413-PA;LFUL017219-PA;LFUL017218-PA;LFUL011816-PA;LFUL015402-PA;LFUL009758-PA;LFUL004900-PA;LFUL007684-PA;LFUL009774-PA;LFUL013277-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA Reactome: R-HSA-70370 Galactose catabolism 2 LFUL006901-PA;LFUL015403-PA Reactome: R-HSA-197264 Nicotinamide salvaging 1 LFUL011944-PA Reactome: R-HSA-68884 Mitotic Telophase/Cytokinesis 3 LFUL013045-PA;LFUL012286-PA;LFUL004639-PA KEGG: 00051+5.3.1.8 Fructose and mannose metabolism 1 LFUL006253-PA KEGG: 00998+4.1.1.82 Biosynthesis of various secondary metabolites - part 2 1 LFUL003189-PA MetaCyc: PWY-6944 Androstenedione degradation 3 LFUL018646-PA;LFUL012393-PA;LFUL017943-PA MetaCyc: PWY-7836 Ganglio-series glycosphingolipids biosynthesis 1 LFUL014857-PA MetaCyc: PWY-7077 N-acetyl-D-galactosamine degradation 1 LFUL003224-PA Reactome: R-HSA-5576886 Phase 4 - resting membrane potential 7 LFUL004261-PA;LFUL015243-PA;LFUL004498-PA;LFUL001146-PA;LFUL001666-PA;LFUL008543-PA;LFUL012551-PA MetaCyc: PWY-5871 Ubiquinol-9 biosynthesis (eukaryotic) 4 LFUL017907-PA;LFUL017908-PA;LFUL000814-PA;LFUL002067-PA Reactome: R-HSA-9645722 Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function 1 LFUL010237-PA Reactome: R-HSA-163841 Gamma carboxylation, hypusine formation and arylsulfatase activation 2 LFUL002069-PA;LFUL007591-PA Reactome: R-HSA-9020702 Interleukin-1 signaling 50 LFUL014805-PA;LFUL005608-PA;LFUL018800-PA;LFUL010280-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL001183-PA;LFUL012905-PA;LFUL010331-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA;LFUL011803-PA;LFUL015886-PA;LFUL011816-PA;LFUL015402-PA;LFUL017219-PA;LFUL014254-PA;LFUL017218-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL007684-PA;LFUL009774-PA;LFUL014255-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL003914-PA;LFUL018127-PA;LFUL009759-PA;LFUL013254-PA;LFUL006784-PA;LFUL005128-PA;LFUL005189-PA;LFUL017408-PA;LFUL015825-PA;LFUL019638-PA;LFUL017243-PA;LFUL015255-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL007901-PA;LFUL013396-PA;LFUL018125-PA;LFUL000664-PA;LFUL016970-PA;LFUL003567-PA MetaCyc: PWY-6609 Adenine and adenosine salvage III 3 LFUL011578-PA;LFUL011577-PA;LFUL003389-PA Reactome: R-HSA-203641 NOSTRIN mediated eNOS trafficking 1 LFUL014120-PA MetaCyc: PWY-5538 Pyruvate fermentation to acetate VI 4 LFUL006472-PA;LFUL004029-PA;LFUL005914-PA;LFUL016366-PA KEGG: 00630+6.3.1.2 Glyoxylate and dicarboxylate metabolism 1 LFUL012349-PA KEGG: 00450+1.8.1.9 Selenocompound metabolism 2 LFUL014831-PA;LFUL011117-PA KEGG: 00562+3.1.3.36 Inositol phosphate metabolism 2 LFUL008439-PA;LFUL008204-PA Reactome: R-HSA-1221632 Meiotic synapsis 7 LFUL006602-PA;LFUL011405-PA;LFUL006719-PA;LFUL008534-PA;LFUL009541-PA;LFUL006718-PA;LFUL000175-PA Reactome: R-HSA-2644607 Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling 1 LFUL015886-PA KEGG: 00250+2.1.3.2 Alanine, aspartate and glutamate metabolism 1 LFUL014037-PA Reactome: R-HSA-1632852 Macroautophagy 42 LFUL001182-PA;LFUL008702-PA;LFUL006593-PA;LFUL006278-PA;LFUL008703-PA;LFUL010265-PA;LFUL006147-PA;LFUL015758-PA;LFUL012151-PA;LFUL008160-PA;LFUL016965-PA;LFUL006345-PA;LFUL019737-PA;LFUL012034-PA;LFUL004611-PA;LFUL004580-PA;LFUL004053-PA;LFUL010339-PA;LFUL001193-PA;LFUL008564-PA;LFUL004570-PA;LFUL003800-PA;LFUL017170-PA;LFUL004581-PA;LFUL019454-PA;LFUL004861-PA;LFUL000119-PA;LFUL006935-PA;LFUL001475-PA;LFUL004571-PA;LFUL006140-PA;LFUL009573-PA;LFUL002108-PA;LFUL005590-PA;LFUL001585-PA;LFUL012362-PA;LFUL016180-PA;LFUL003840-PA;LFUL001476-PA;LFUL001073-PA;LFUL011021-PA;LFUL009057-PA Reactome: R-HSA-156827 L13a-mediated translational silencing of Ceruloplasmin expression 90 LFUL007452-PA;LFUL004596-PA;LFUL010862-PA;LFUL008669-PA;LFUL017447-PA;LFUL008661-PA;LFUL018772-PA;LFUL015696-PA;LFUL018435-PA;LFUL000390-PA;LFUL014304-PA;LFUL002925-PA;LFUL002249-PA;LFUL019701-PA;LFUL006675-PA;LFUL011123-PA;LFUL014007-PA;LFUL014225-PA;LFUL004229-PA;LFUL006093-PA;LFUL001681-PA;LFUL002208-PA;LFUL017656-PA;LFUL005636-PA;LFUL014893-PA;LFUL011278-PA;LFUL008016-PA;LFUL003947-PA;LFUL004974-PA;LFUL012271-PA;LFUL006720-PA;LFUL018953-PA;LFUL001102-PA;LFUL001937-PA;LFUL019054-PA;LFUL009762-PA;LFUL012702-PA;LFUL017288-PA;LFUL007583-PA;LFUL007358-PA;LFUL002211-PA;LFUL002324-PA;LFUL009630-PA;LFUL010424-PA;LFUL017793-PA;LFUL004637-PA;LFUL008330-PA;LFUL006788-PA;LFUL001962-PA;LFUL006902-PA;LFUL011563-PA;LFUL002950-PA;LFUL015920-PA;LFUL016269-PA;LFUL016069-PA;LFUL001176-PA;LFUL015341-PA;LFUL004636-PA;LFUL004420-PA;LFUL015591-PA;LFUL010275-PA;LFUL016059-PA;LFUL012852-PA;LFUL012372-PA;LFUL010697-PA;LFUL005171-PA;LFUL016060-PA;LFUL018996-PA;LFUL006873-PA;LFUL009487-PA;LFUL013851-PA;LFUL017436-PA;LFUL000050-PA;LFUL005935-PA;LFUL003221-PA;LFUL018450-PA;LFUL006255-PA;LFUL019500-PA;LFUL009485-PA;LFUL001717-PA;LFUL000695-PA;LFUL006688-PA;LFUL004537-PA;LFUL002673-PA;LFUL006445-PA;LFUL003261-PA;LFUL001329-PA;LFUL004418-PA;LFUL010852-PA;LFUL011000-PA MetaCyc: PWY-5651 L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde 3 LFUL008866-PA;LFUL008867-PA;LFUL015273-PA Reactome: R-HSA-727802 Transport of nucleotide sugars 1 LFUL017954-PA KEGG: 00052+2.7.1.11 Galactose metabolism 2 LFUL011354-PA;LFUL011355-PA KEGG: 00510+2.4.1.259+2.4.1.261 N-Glycan biosynthesis 1 LFUL004439-PA MetaCyc: PWY-5667 CDP-diacylglycerol biosynthesis I 11 LFUL014100-PA;LFUL017634-PA;LFUL002099-PA;LFUL007247-PA;LFUL016130-PA;LFUL016131-PA;LFUL016045-PA;LFUL016603-PA;LFUL013010-PA;LFUL008878-PA;LFUL009878-PA Reactome: R-HSA-427389 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression 3 LFUL002061-PA;LFUL009328-PA;LFUL000180-PA Reactome: R-HSA-5693568 Resolution of D-loop Structures through Holliday Junction Intermediates 27 LFUL007096-PA;LFUL003121-PA;LFUL002671-PA;LFUL006936-PA;LFUL007836-PA;LFUL001598-PA;LFUL007979-PA;LFUL001126-PA;LFUL004632-PA;LFUL011482-PA;LFUL003753-PA;LFUL007471-PA;LFUL004270-PA;LFUL014611-PA;LFUL004631-PA;LFUL014965-PA;LFUL006792-PA;LFUL006344-PA;LFUL003194-PA;LFUL014004-PA;LFUL010680-PA;LFUL017965-PA;LFUL014612-PA;LFUL018992-PA;LFUL007832-PA;LFUL008071-PA;LFUL005650-PA Reactome: R-HSA-73780 RNA Polymerase III Chain Elongation 17 LFUL006931-PA;LFUL003390-PA;LFUL010364-PA;LFUL010060-PA;LFUL003284-PA;LFUL013037-PA;LFUL010762-PA;LFUL011471-PA;LFUL010061-PA;LFUL006932-PA;LFUL001373-PA;LFUL014846-PA;LFUL002481-PA;LFUL014294-PA;LFUL003911-PA;LFUL000388-PA;LFUL017259-PA Reactome: R-HSA-180024 DARPP-32 events 8 LFUL005115-PA;LFUL004449-PA;LFUL004450-PA;LFUL004452-PA;LFUL004454-PA;LFUL015154-PA;LFUL005116-PA;LFUL004453-PA Reactome: R-HSA-204174 Regulation of pyruvate dehydrogenase (PDH) complex 4 LFUL009335-PA;LFUL016974-PA;LFUL010747-PA;LFUL008261-PA MetaCyc: PWY-6117 Spermine and spermidine degradation I 1 LFUL017216-PA KEGG: 00561+3.1.3.4 Glycerolipid metabolism 3 LFUL011019-PA;LFUL005920-PA;LFUL011020-PA KEGG: 04660+3.1.3.16 T cell receptor signaling pathway 36 LFUL001158-PA;LFUL004450-PA;LFUL004449-PA;LFUL001499-PA;LFUL001498-PA;LFUL012152-PA;LFUL014700-PA;LFUL004453-PA;LFUL002996-PA;LFUL014533-PA;LFUL005424-PA;LFUL014211-PA;LFUL004454-PA;LFUL004452-PA;LFUL018043-PA;LFUL018100-PA;LFUL018101-PA;LFUL018679-PA;LFUL006251-PA;LFUL017164-PA;LFUL017117-PA;LFUL006643-PA;LFUL019606-PA;LFUL008095-PA;LFUL015075-PA;LFUL010894-PA;LFUL004309-PA;LFUL002610-PA;LFUL014885-PA;LFUL007186-PA;LFUL001904-PA;LFUL011767-PA;LFUL013098-PA;LFUL002524-PA;LFUL013235-PA;LFUL000398-PA KEGG: 00460+2.1.2.1 Cyanoamino acid metabolism 3 LFUL001565-PA;LFUL009609-PA;LFUL004544-PA KEGG: 00280+4.2.1.17+1.1.1.35 Valine, leucine and isoleucine degradation 3 LFUL017943-PA;LFUL012393-PA;LFUL018646-PA KEGG: 00480+3.4.11.2 Glutathione metabolism 11 LFUL009852-PA;LFUL010190-PA;LFUL009851-PA;LFUL015481-PA;LFUL019687-PA;LFUL015485-PA;LFUL015482-PA;LFUL015480-PA;LFUL015484-PA;LFUL010189-PA;LFUL015479-PA Reactome: R-HSA-1222556 ROS and RNS production in phagocytes 16 LFUL001456-PA;LFUL006476-PA;LFUL008406-PA;LFUL011205-PA;LFUL011203-PA;LFUL011204-PA;LFUL003394-PA;LFUL008957-PA;LFUL009771-PA;LFUL010201-PA;LFUL006212-PA;LFUL018924-PA;LFUL009162-PA;LFUL006787-PA;LFUL010191-PA;LFUL010662-PA KEGG: 00680+3.1.3.11 Methane metabolism 2 LFUL000567-PA;LFUL000566-PA Reactome: R-HSA-176408 Regulation of APC/C activators between G1/S and early anaphase 11 LFUL006381-PA;LFUL013953-PA;LFUL000448-PA;LFUL002279-PA;LFUL011826-PA;LFUL011394-PA;LFUL006691-PA;LFUL001285-PA;LFUL011827-PA;LFUL004085-PA;LFUL008983-PA Reactome: R-HSA-2173795 Downregulation of SMAD2/3:SMAD4 transcriptional activity 1 LFUL004537-PA KEGG: 00620+2.3.1.12 Pyruvate metabolism 1 LFUL008261-PA Reactome: R-HSA-1538133 G0 and Early G1 4 LFUL014016-PA;LFUL013765-PA;LFUL000101-PA;LFUL014149-PA Reactome: R-HSA-111367 SLBP independent Processing of Histone Pre-mRNAs 5 LFUL009060-PA;LFUL000565-PA;LFUL016599-PA;LFUL000564-PA;LFUL016290-PA Reactome: R-HSA-2871837 FCERI mediated NF-kB activation 47 LFUL016970-PA;LFUL000664-PA;LFUL018125-PA;LFUL003567-PA;LFUL017243-PA;LFUL000924-PA;LFUL013396-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL007901-PA;LFUL015255-PA;LFUL005128-PA;LFUL005189-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL016470-PA;LFUL003914-PA;LFUL009759-PA;LFUL018127-PA;LFUL006784-PA;LFUL013254-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL009758-PA;LFUL001183-PA;LFUL010331-PA;LFUL010327-PA;LFUL017608-PA;LFUL018065-PA;LFUL013520-PA;LFUL001413-PA;LFUL015886-PA;LFUL001632-PA;LFUL014805-PA;LFUL005608-PA;LFUL010280-PA KEGG: 00591+3.1.1.4 Linoleic acid metabolism 20 LFUL013309-PA;LFUL019491-PA;LFUL013307-PA;LFUL016033-PA;LFUL010843-PA;LFUL013311-PA;LFUL004585-PA;LFUL013308-PA;LFUL012016-PA;LFUL002720-PA;LFUL016035-PA;LFUL016034-PA;LFUL016031-PA;LFUL012592-PA;LFUL016032-PA;LFUL002721-PA;LFUL016881-PA;LFUL002722-PA;LFUL011621-PA;LFUL013310-PA Reactome: R-HSA-964975 Vitamins B6 activation to pyridoxal phosphate 4 LFUL006014-PA;LFUL009425-PA;LFUL013559-PA;LFUL012528-PA Reactome: R-HSA-5610783 Degradation of GLI2 by the proteasome 43 LFUL004537-PA;LFUL001667-PA;LFUL013396-PA;LFUL005657-PA;LFUL007901-PA;LFUL015255-PA;LFUL017243-PA;LFUL016970-PA;LFUL000664-PA;LFUL003567-PA;LFUL003914-PA;LFUL006784-PA;LFUL013254-PA;LFUL009759-PA;LFUL005128-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL017218-PA;LFUL017219-PA;LFUL015402-PA;LFUL011816-PA;LFUL009758-PA;LFUL004900-PA;LFUL009774-PA;LFUL007684-PA;LFUL013277-PA;LFUL010441-PA;LFUL003913-PA;LFUL011817-PA;LFUL014805-PA;LFUL010552-PA;LFUL005608-PA;LFUL008156-PA;LFUL013520-PA;LFUL001183-PA;LFUL010331-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL015886-PA;LFUL001632-PA;LFUL001413-PA KEGG: 00240+2.4.2.1 Pyrimidine metabolism 2 LFUL011577-PA;LFUL011578-PA Reactome: R-HSA-177929 Signaling by EGFR 2 LFUL009003-PA;LFUL015476-PA Reactome: R-HSA-1237044 Erythrocytes take up carbon dioxide and release oxygen 3 LFUL005879-PA;LFUL001746-PA;LFUL001395-PA KEGG: 00730+3.6.1.15 Thiamine metabolism 1 LFUL005425-PA KEGG: 00250+6.3.5.5 Alanine, aspartate and glutamate metabolism 4 LFUL014041-PA;LFUL014039-PA;LFUL014040-PA;LFUL014042-PA KEGG: 00640+1.3.3.6 Propanoate metabolism 2 LFUL001447-PA;LFUL001448-PA Reactome: R-HSA-76005 Response to elevated platelet cytosolic Ca2+ 1 LFUL007151-PA MetaCyc: PWY-7382 Lipoate biosynthesis and incorporation IV (yeast) 5 LFUL002318-PA;LFUL004144-PA;LFUL008960-PA;LFUL004145-PA;LFUL003022-PA Reactome: R-HSA-2024096 HS-GAG degradation 9 LFUL018950-PA;LFUL003653-PA;LFUL012024-PA;LFUL002624-PA;LFUL002623-PA;LFUL006883-PA;LFUL014772-PA;LFUL009642-PA;LFUL005814-PA Reactome: R-HSA-446210 Synthesis of UDP-N-acetyl-glucosamine 4 LFUL003416-PA;LFUL003224-PA;LFUL002889-PA;LFUL002126-PA MetaCyc: PWY-7728 (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase) 2 LFUL010698-PA;LFUL001272-PA Reactome: R-HSA-400206 Regulation of lipid metabolism by PPARalpha 3 LFUL015835-PA;LFUL008336-PA;LFUL018367-PA Reactome: R-HSA-69205 G1/S-Specific Transcription 15 LFUL019090-PA;LFUL002258-PA;LFUL015871-PA;LFUL014016-PA;LFUL007804-PA;LFUL002259-PA;LFUL006665-PA;LFUL017714-PA;LFUL012409-PA;LFUL013765-PA;LFUL000101-PA;LFUL015135-PA;LFUL017711-PA;LFUL014586-PA;LFUL014149-PA MetaCyc: PWY-7782 Plasmalogen biosynthesis 31 LFUL008789-PA;LFUL011020-PA;LFUL018767-PA;LFUL002099-PA;LFUL005920-PA;LFUL012819-PA;LFUL001619-PA;LFUL013655-PA;LFUL013656-PA;LFUL018155-PA;LFUL011019-PA;LFUL013658-PA;LFUL010157-PA;LFUL016045-PA;LFUL012813-PA;LFUL012820-PA;LFUL015965-PA;LFUL012814-PA;LFUL010158-PA;LFUL017634-PA;LFUL015964-PA;LFUL012817-PA;LFUL002995-PA;LFUL012816-PA;LFUL008878-PA;LFUL018152-PA;LFUL013657-PA;LFUL009878-PA;LFUL012818-PA;LFUL012811-PA;LFUL018766-PA Reactome: R-HSA-8963888 Chylomicron assembly 10 LFUL019397-PA;LFUL013535-PA;LFUL018063-PA;LFUL018058-PA;LFUL012561-PA;LFUL009525-PA;LFUL013537-PA;LFUL000686-PA;LFUL018059-PA;LFUL005945-PA KEGG: 00270+4.4.1.13 Cysteine and methionine metabolism 2 LFUL013723-PA;LFUL013724-PA KEGG: 00040+1.1.1.22 Pentose and glucuronate interconversions 1 LFUL010590-PA KEGG: 00010+4.2.1.11 Glycolysis / Gluconeogenesis 1 LFUL011112-PA MetaCyc: PWY-6664 Di-myo-inositol phosphate biosynthesis 1 LFUL014193-PA Reactome: R-HSA-418346 Platelet homeostasis 5 LFUL003556-PA;LFUL007272-PA;LFUL007630-PA;LFUL001443-PA;LFUL007631-PA MetaCyc: PWY-4202 Arsenate detoxification I (mammalian) 2 LFUL011578-PA;LFUL011577-PA KEGG: 04660+2.7.10.2 T cell receptor signaling pathway 7 LFUL000232-PA;LFUL005613-PA;LFUL004084-PA;LFUL002340-PA;LFUL001108-PA;LFUL014233-PA;LFUL016685-PA Reactome: R-HSA-2299718 Condensation of Prophase Chromosomes 5 LFUL006469-PA;LFUL006468-PA;LFUL016663-PA;LFUL007522-PA;LFUL014386-PA KEGG: 00290+4.2.1.33 Valine, leucine and isoleucine biosynthesis 2 LFUL012627-PA;LFUL013084-PA Reactome: R-HSA-8862803 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models 3 LFUL008385-PA;LFUL000159-PA;LFUL014905-PA Reactome: R-HSA-427652 Sodium-coupled phosphate cotransporters 4 LFUL010006-PA;LFUL010008-PA;LFUL010007-PA;LFUL010005-PA MetaCyc: PWY-4381 Fatty acid biosynthesis initiation (bacteria and plants) 4 LFUL010442-PA;LFUL006083-PA;LFUL009296-PA;LFUL005606-PA KEGG: 00350+1.13.11.5 Tyrosine metabolism 2 LFUL012336-PA;LFUL012337-PA MetaCyc: PWY-7174 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II 4 LFUL019224-PA;LFUL003374-PA;LFUL010188-PA;LFUL018466-PA Reactome: R-HSA-70263 Gluconeogenesis 11 LFUL011112-PA;LFUL008549-PA;LFUL015710-PA;LFUL001099-PA;LFUL010175-PA;LFUL005591-PA;LFUL011512-PA;LFUL004113-PA;LFUL015809-PA;LFUL000566-PA;LFUL000567-PA Reactome: R-HSA-909733 Interferon alpha/beta signaling 1 LFUL010863-PA Reactome: R-HSA-5619078 Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C) 1 LFUL017954-PA Reactome: R-HSA-9022702 MECP2 regulates transcription of neuronal ligands 1 LFUL008336-PA Reactome: R-HSA-3214858 RMTs methylate histone arginines 20 LFUL018622-PA;LFUL004898-PA;LFUL010816-PA;LFUL013681-PA;LFUL006362-PA;LFUL004988-PA;LFUL009658-PA;LFUL018025-PA;LFUL000742-PA;LFUL006199-PA;LFUL013089-PA;LFUL005566-PA;LFUL002644-PA;LFUL018026-PA;LFUL015591-PA;LFUL005567-PA;LFUL004989-PA;LFUL007175-PA;LFUL000743-PA;LFUL019711-PA Reactome: R-HSA-1299308 Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK) 1 LFUL004498-PA MetaCyc: PWY-5030 L-histidine degradation III 4 LFUL004916-PA;LFUL014192-PA;LFUL005329-PA;LFUL003915-PA MetaCyc: PWY-7560 Methylerythritol phosphate pathway II 2 LFUL008593-PA;LFUL006367-PA KEGG: 00140+1.14.14.1 Steroid hormone biosynthesis 2 LFUL007894-PA;LFUL019543-PA KEGG: 00910+4.2.1.1 Nitrogen metabolism 5 LFUL012802-PA;LFUL010584-PA;LFUL012803-PA;LFUL004391-PA;LFUL017492-PA Reactome: R-HSA-8964041 LDL remodeling 5 LFUL018058-PA;LFUL005945-PA;LFUL018059-PA;LFUL013535-PA;LFUL019397-PA Reactome: R-HSA-975578 Reactions specific to the complex N-glycan synthesis pathway 2 LFUL011017-PA;LFUL018519-PA KEGG: 00250+6.3.5.4 Alanine, aspartate and glutamate metabolism 1 LFUL005206-PA Reactome: R-HSA-392451 G beta:gamma signalling through PI3Kgamma 6 LFUL000924-PA;LFUL000620-PA;LFUL012255-PA;LFUL000640-PA;LFUL017104-PA;LFUL003893-PA MetaCyc: PWY-5972 Stearate biosynthesis I (animals) 16 LFUL001095-PA;LFUL017948-PA;LFUL012360-PA;LFUL015422-PA;LFUL013818-PA;LFUL004766-PA;LFUL007078-PA;LFUL013816-PA;LFUL013817-PA;LFUL002423-PA;LFUL012361-PA;LFUL006533-PA;LFUL013815-PA;LFUL015420-PA;LFUL012359-PA;LFUL013814-PA Reactome: R-HSA-110373 Resolution of AP sites via the multiple-nucleotide patch replacement pathway 1 LFUL008002-PA MetaCyc: PWY-5895 Menaquinol-13 biosynthesis 2 LFUL006592-PA;LFUL006594-PA Reactome: R-HSA-9610379 HCMV Late Events 32 LFUL002957-PA;LFUL000581-PA;LFUL000200-PA;LFUL005157-PA;LFUL006358-PA;LFUL010282-PA;LFUL011549-PA;LFUL012973-PA;LFUL016880-PA;LFUL002532-PA;LFUL010679-PA;LFUL006398-PA;LFUL008608-PA;LFUL016186-PA;LFUL001539-PA;LFUL005156-PA;LFUL015687-PA;LFUL018131-PA;LFUL009840-PA;LFUL003450-PA;LFUL013801-PA;LFUL010864-PA;LFUL012732-PA;LFUL005565-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL002533-PA;LFUL008059-PA;LFUL002666-PA;LFUL006282-PA;LFUL002956-PA MetaCyc: PWY-7082 Ammonia oxidation IV (autotrophic ammonia oxidizers) 1 LFUL009172-PA Reactome: R-HSA-2408508 Metabolism of ingested SeMet, Sec, MeSec into H2Se 3 LFUL001880-PA;LFUL001879-PA;LFUL001927-PA Reactome: R-HSA-5362768 Hh mutants that don't undergo autocatalytic processing are degraded by ERAD 44 LFUL017243-PA;LFUL013396-PA;LFUL004537-PA;LFUL001667-PA;LFUL005657-PA;LFUL007901-PA;LFUL015255-PA;LFUL000664-PA;LFUL016970-PA;LFUL003567-PA;LFUL017168-PA;LFUL003914-PA;LFUL005006-PA;LFUL009759-PA;LFUL006784-PA;LFUL007460-PA;LFUL013254-PA;LFUL005128-PA;LFUL019638-PA;LFUL017408-PA;LFUL015825-PA;LFUL015402-PA;LFUL011816-PA;LFUL017218-PA;LFUL017219-PA;LFUL004900-PA;LFUL009758-PA;LFUL013277-PA;LFUL009774-PA;LFUL007684-PA;LFUL004108-PA;LFUL003913-PA;LFUL010441-PA;LFUL011817-PA;LFUL014805-PA;LFUL005608-PA;LFUL001183-PA;LFUL010331-PA;LFUL018065-PA;LFUL010327-PA;LFUL017608-PA;LFUL013520-PA;LFUL001413-PA;LFUL001632-PA MetaCyc: PWY-3781 Aerobic respiration I (cytochrome c) 3 LFUL001123-PA;LFUL008263-PA;LFUL009172-PA Reactome: R-HSA-181430 Norepinephrine Neurotransmitter Release Cycle 2 LFUL010868-PA;LFUL010866-PA KEGG: 00830+1.14.14.1 Retinol metabolism 2 LFUL007894-PA;LFUL019543-PA Reactome: R-HSA-112126 ALKBH3 mediated reversal of alkylation damage 1 LFUL005795-PA Reactome: R-HSA-8940973 RUNX2 regulates osteoblast differentiation 6 LFUL009516-PA;LFUL009514-PA;LFUL002340-PA;LFUL014137-PA;LFUL009515-PA;LFUL009513-PA Reactome: R-HSA-5083633 Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1 5 LFUL009334-PA;LFUL003867-PA;LFUL003866-PA;LFUL004914-PA;LFUL004915-PA Reactome: R-HSA-381042 PERK regulates gene expression 3 LFUL002211-PA;LFUL008294-PA;LFUL015267-PA Reactome: R-HSA-450520 HuR (ELAVL1) binds and stabilizes mRNA 1 LFUL004116-PA KEGG: 00710+1.1.1.37 Carbon fixation in photosynthetic organisms 3 LFUL004114-PA;LFUL004113-PA;LFUL015809-PA Reactome: R-HSA-77310 Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA 1 LFUL017943-PA Reactome: R-HSA-6790901 rRNA modification in the nucleus and cytosol 51 LFUL015591-PA;LFUL009314-PA;LFUL002939-PA;LFUL009163-PA;LFUL009607-PA;LFUL006622-PA;LFUL015889-PA;LFUL007907-PA;LFUL013536-PA;LFUL002940-PA;LFUL002750-PA;LFUL004637-PA;LFUL013343-PA;LFUL009098-PA;LFUL008611-PA;LFUL002127-PA;LFUL004353-PA;LFUL007908-PA;LFUL006085-PA;LFUL001204-PA;LFUL004636-PA;LFUL015338-PA;LFUL003488-PA;LFUL006624-PA;LFUL003541-PA;LFUL006075-PA;LFUL008422-PA;LFUL006337-PA;LFUL008018-PA;LFUL014741-PA;LFUL002448-PA;LFUL011333-PA;LFUL017793-PA;LFUL012669-PA;LFUL011000-PA;LFUL013323-PA;LFUL003424-PA;LFUL009872-PA;LFUL010404-PA;LFUL011456-PA;LFUL002208-PA;LFUL008430-PA;LFUL007470-PA;LFUL003396-PA;LFUL013344-PA;LFUL011725-PA;LFUL005093-PA;LFUL019182-PA;LFUL008612-PA;LFUL004565-PA;LFUL013342-PA Reactome: R-HSA-1810476 RIP-mediated NFkB activation via ZBP1 3 LFUL003145-PA;LFUL018800-PA;LFUL010280-PA Reactome: R-HSA-5620924 Intraflagellar transport 18 LFUL006593-PA;LFUL011025-PA;LFUL014295-PA;LFUL006192-PA;LFUL009664-PA;LFUL003140-PA;LFUL008080-PA;LFUL011726-PA;LFUL002509-PA;LFUL008322-PA;LFUL003946-PA;LFUL005316-PA;LFUL002151-PA;LFUL002188-PA;LFUL006144-PA;LFUL016909-PA;LFUL007348-PA;LFUL011026-PA KEGG: 00232+2.3.1.5 Caffeine metabolism 1 LFUL000219-PA KEGG: 00670+2.1.2.3 One carbon pool by folate 2 LFUL015684-PA;LFUL015685-PA Reactome: R-HSA-8878166 Transcriptional regulation by RUNX2 4 LFUL009516-PA;LFUL009514-PA;LFUL009515-PA;LFUL009513-PA MetaCyc: PWY-601 Glucosinolate biosynthesis from tryptophan 2 LFUL013723-PA;LFUL013724-PA KEGG: 00051+5.3.1.1 Fructose and mannose metabolism 1 LFUL005591-PA Reactome: R-HSA-948021 Transport to the Golgi and subsequent modification 1 LFUL017724-PA Reactome: R-HSA-5389840 Mitochondrial translation elongation 68 LFUL004130-PA;LFUL001663-PA;LFUL017525-PA;LFUL001538-PA;LFUL004509-PA;LFUL001176-PA;LFUL007900-PA;LFUL006854-PA;LFUL019763-PA;LFUL003929-PA;LFUL003473-PA;LFUL010873-PA;LFUL002738-PA;LFUL000609-PA;LFUL004614-PA;LFUL001460-PA;LFUL001323-PA;LFUL008019-PA;LFUL007295-PA;LFUL009337-PA;LFUL002976-PA;LFUL003376-PA;LFUL005053-PA;LFUL011692-PA;LFUL001850-PA;LFUL007422-PA;LFUL005481-PA;LFUL014313-PA;LFUL007667-PA;LFUL007193-PA;LFUL004190-PA;LFUL002078-PA;LFUL015233-PA;LFUL000344-PA;LFUL010173-PA;LFUL010294-PA;LFUL009757-PA;LFUL014538-PA;LFUL017732-PA;LFUL007188-PA;LFUL011887-PA;LFUL001184-PA;LFUL017828-PA;LFUL009315-PA;LFUL003101-PA;LFUL004956-PA;LFUL007191-PA;LFUL008017-PA;LFUL010234-PA;LFUL015276-PA;LFUL000080-PA;LFUL006429-PA;LFUL005723-PA;LFUL012340-PA;LFUL002294-PA;LFUL012906-PA;LFUL014003-PA;LFUL015537-PA;LFUL007369-PA;LFUL000320-PA;LFUL007542-PA;LFUL014875-PA;LFUL011340-PA;LFUL004150-PA;LFUL017678-PA;LFUL013892-PA;LFUL005922-PA;LFUL012013-PA Reactome: R-HSA-113507 E2F-enabled inhibition of pre-replication complex formation 5 LFUL002734-PA;LFUL012084-PA;LFUL012083-PA;LFUL014903-PA;LFUL012409-PA Reactome: R-HSA-3928662 EPHB-mediated forward signaling 12 LFUL005511-PA;LFUL015508-PA;LFUL010848-PA;LFUL007319-PA;LFUL013420-PA;LFUL014180-PA;LFUL005324-PA;LFUL001806-PA;LFUL000248-PA;LFUL010847-PA;LFUL006478-PA;LFUL009182-PA KEGG: 00260+1.2.1.8+1.1.99.1 Glycine, serine and threonine metabolism 1 LFUL008143-PA KEGG: 05235+3.1.3.16 PD-L1 expression and PD-1 checkpoint pathway in cancer 36 LFUL002610-PA;LFUL007186-PA;LFUL014885-PA;LFUL019606-PA;LFUL008095-PA;LFUL015075-PA;LFUL010894-PA;LFUL004309-PA;LFUL011767-PA;LFUL002524-PA;LFUL013098-PA;LFUL013235-PA;LFUL000398-PA;LFUL001904-PA;LFUL001499-PA;LFUL001498-PA;LFUL012152-PA;LFUL014700-PA;LFUL004453-PA;LFUL002996-PA;LFUL014533-PA;LFUL001158-PA;LFUL004450-PA;LFUL004449-PA;LFUL006251-PA;LFUL017164-PA;LFUL017117-PA;LFUL006643-PA;LFUL005424-PA;LFUL014211-PA;LFUL004454-PA;LFUL004452-PA;LFUL018043-PA;LFUL018100-PA;LFUL018101-PA;LFUL018679-PA Reactome: R-HSA-190840 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 15 LFUL010682-PA;LFUL004646-PA;LFUL013557-PA;LFUL013555-PA;LFUL010020-PA;LFUL014801-PA;LFUL014799-PA;LFUL014793-PA;LFUL010681-PA;LFUL014800-PA;LFUL014795-PA;LFUL012256-PA;LFUL013561-PA;LFUL003377-PA;LFUL013560-PA KEGG: 00010+5.4.2.11 Glycolysis / Gluconeogenesis 1 LFUL008386-PA MetaCyc: PWY-5966-1 Fatty acid biosynthesis initiation (animals and fungi, cytoplasm) 2 LFUL006083-PA;LFUL005606-PA KEGG: 00350+1.14.16.2 Tyrosine metabolism 2 LFUL004046-PA;LFUL004047-PA Reactome: R-HSA-167200 Formation of HIV-1 elongation complex containing HIV-1 Tat 35 LFUL004554-PA;LFUL000398-PA;LFUL002212-PA;LFUL006931-PA;LFUL013037-PA;LFUL003284-PA;LFUL007672-PA;LFUL014212-PA;LFUL000565-PA;LFUL010364-PA;LFUL014608-PA;LFUL006416-PA;LFUL003797-PA;LFUL006932-PA;LFUL001415-PA;LFUL016326-PA;LFUL010467-PA;LFUL010456-PA;LFUL008550-PA;LFUL004885-PA;LFUL016324-PA;LFUL008342-PA;LFUL018856-PA;LFUL010620-PA;LFUL015513-PA;LFUL008825-PA;LFUL003397-PA;LFUL010468-PA;LFUL002536-PA;LFUL001373-PA;LFUL008343-PA;LFUL000564-PA;LFUL003393-PA;LFUL013636-PA;LFUL008827-PA MetaCyc: PWY-6945 Cholesterol degradation to androstenedione I (cholesterol oxidase) 3 LFUL018646-PA;LFUL017943-PA;LFUL012393-PA KEGG: 00710+2.7.1.14 Carbon fixation in photosynthetic organisms 1 LFUL006583-PA KEGG: 00030+4.1.2.13 Pentose phosphate pathway 1 LFUL011512-PA MetaCyc: PWY-5461 Betanidin degradation 7 LFUL010193-PA;LFUL010194-PA;LFUL010195-PA;LFUL006904-PA;LFUL006897-PA;LFUL004976-PA;LFUL019366-PA KEGG: 04070+3.1.3.25 Phosphatidylinositol signaling system 1 LFUL003784-PA MetaCyc: PWY-8012 Mupirocin biosynthesis 1 LFUL006083-PA KEGG: 00230+3.1.4.53 Purine metabolism 2 LFUL005116-PA;LFUL005115-PA KEGG: 00230+2.7.4.10 Purine metabolism 1 LFUL008697-PA Reactome: R-HSA-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes 4 LFUL009516-PA;LFUL009514-PA;LFUL009515-PA;LFUL009513-PA KEGG: 00740+2.7.1.26 Riboflavin metabolism 1 LFUL005319-PA Reactome: R-HSA-5339700 TCF7L2 mutants don't bind CTBP 1 LFUL016876-PA MetaCyc: PWY-5839 Menaquinol-7 biosynthesis 2 LFUL006592-PA;LFUL006594-PA MetaCyc: PWY-6309 L-tryptophan degradation XI (mammalian, via kynurenine) 5 LFUL013723-PA;LFUL008867-PA;LFUL008866-PA;LFUL015273-PA;LFUL013724-PA MetaCyc: PWY-181 Photorespiration 3 LFUL001565-PA;LFUL009609-PA;LFUL004544-PA Reactome: R-HSA-1169408 ISG15 antiviral mechanism 29 LFUL004473-PA;LFUL002532-PA;LFUL009305-PA;LFUL013881-PA;LFUL009303-PA;LFUL004537-PA;LFUL008059-PA;LFUL002533-PA;LFUL000747-PA;LFUL016186-PA;LFUL000581-PA;LFUL010864-PA;LFUL009193-PA;LFUL005565-PA;LFUL016880-PA;LFUL006358-PA;LFUL000200-PA;LFUL005157-PA;LFUL011549-PA;LFUL015687-PA;LFUL006282-PA;LFUL006167-PA;LFUL005156-PA;LFUL013801-PA;LFUL018131-PA;LFUL009840-PA;LFUL018435-PA;LFUL002666-PA;LFUL018437-PA Reactome: R-HSA-4420332 Defective B3GALT6 causes EDSP2 and SEMDJL1 4 LFUL005814-PA;LFUL009642-PA;LFUL002623-PA;LFUL002624-PA Reactome: R-HSA-1234174 Cellular response to hypoxia 2 LFUL005824-PA;LFUL014616-PA